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mayerdohn66 · 10 months

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Acute Pancreatitis: Signs, Treatment, Causes, And Issues

My wife and I just bought a model new house and were in the strategy of decorating it and putting within the landscaping. When gallstones cause a severe attack of acute pancreatitis, the remedy plan may include attempts to remove the stone(s). Unintended weight reduction is fairly common in individuals with pancreatic cancer. Veterinarians diagnose hepatic lipidosis based on a cat's history, bodily examination findings, blood tests, and abdominal ultrasonography. The diagnosis is confirmed by analyzing a sample of the liver taken with an ultrasound-guided needle. To diagnose some causes of hepatic lipidosis, a larger biopsy must be taken during surgery. This test is used to seek out out if you might have a condition that impacts your pancreas or salivary glands. The alpha-2 adrenergic receptor is a G-protein coupled receptor (GPCR) current in all kinds of tissues, corresponding to vascular clean muscle, coronary arteries, salivary glands and the gastrointestinal tract. Its particular actions on the gastrointestinal tract embody contraction of sphincters and decreased motility of the graceful muscle inside the gastrointestinal tract [4, 5]. Activation of the alpha-2 receptor causes contraction of the hepato-pancreatic sphincter (sphincter of oddi), resulting in obstruction of pancreatic enzyme move through the pancreatic duct, resulting in acute pancreatitis. Like IL-6, they're usually not utilized in clinical follow and are more expensive than sometimes used tests. Abdominal radiographs have a limited role in acute pancreatitis. In some circumstances, the inflammatory process might harm peripancreatic structures, resulting in a colon cut-off signal, a sentinel loop, or an ileus. The presence of calcifications within or across the pancreas might indicate persistent pancreatitis. Serum amylase and lipase levels are usually elevated in individuals with acute pancreatitis. In research research, amylase or lipase levels a minimal of 3 instances above the reference vary are typically considered diagnostic of acute pancreatitis. Thus, this method appears to carry promise for the therapy of patients with ALD. Although alcoholic beverages comprise energy, analysis means that underneath sure conditions these energy wouldn't have as much worth for the physique as those derived from other nutrients. In addition, many alcoholics suffer from malnutrition, which might result in liver harm and impaired liver perform. Many drinkers take in lower than the really helpful day by day quantity of carbohydrates, proteins, fats, nutritional vitamins (A, C, and B, especially thiamine [B1]), and minerals (such as calcium and iron). Of the three enzymes, GGT is one of the best indicator of excessive alcohol consumption, but GGT is present in lots of organs and is elevated by different medicine as well, so high GGT levels do not necessarily mean the patient is abusing alcohol. In addition, they could also have fever, loss of urge for food, weight loss, fatigue, night time sweats, joint pains and body aches. Celiac disease is a genetic autoimmune disorder that impacts both kids and grownup. If a child has celiac illness, consuming gluten will cause harm to finger-like projections, called villi, in the lining of the kid's small intestines. This, in flip, interferes with the small intestine’s capability to absorb vitamins in food, leading to malnutrition and a wide selection of different issues. The protein in wheat, barley, rye and oats collectively called “gluten” cause the immune system to form antibodies which then assault the villi. These youngsters with Celiac illness might undergo from symptoms corresponding to belly bloating, pain, gas, diarrhea, constipation, weight reduction, anemia, progress issues, and short stature. high liver enzymes cancer Many completely different tumours may occur inside the liver – some simply affecting the liver (primary liver tumours), some which have spread to the liver from elsewhere (secondary liver tumours). Unfortunately many liver tumours carry a poor prognosis, but this is not invariably the case and with some tumours (eg, lymphoma) chemotherapy could also be possible. Tumours confined to one lobe of the liver can also be amenable to surgical resection. Alcohol consumption and smoking cigarettes can improve the danger of pancreatitis. It is strongly really helpful quitting smoking cigarettes and drinking alcohol to stop pancreatitis. Chronic pancreatitis is much less common and results in 86,000 hospital stays per year. In AP, the serum biochemical indexes of the liver often change, and adjustments in liver function will have an effect on the severity and prognosis of AP. Several drugs can elevate GGT levels, such as phenytoin, phenobarbital, carbamazepine, valproic acid, cimetidine, heparin, methotrexate, furosemide, isotretinoin, and acetaminophen. Likewise, oral contraceptives also can raise the enzyme’s serum level. The size of time you'll have the ability to successfully scale back GGT depends on your actions to deliver the degrees down. For example, if you hand over alcohol, you can see your GGT levels decrease considerably after a month.

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kjelleruprobertson34 · 9 months

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Well Being: Is Keto Food Plan Safe For The Liver

Your healthcare supplier can use a big selection of enzyme and protein blood tests to check for certain health situations. For instance, elevated liver enzymes could probably be a sign of liver disease. If you have high levels of liver enzymes in your blood, you have elevated liver enzymes. High liver enzyme levels could additionally be temporary, or they might be an indication of a medical situation like hepatitis or liver illness. In cholangitis with incomplete extrahepatic obstruction, patients may have normal or barely raised serum bilirubin concentrations and high serum alkaline phosphatase exercise. Serum alkaline phosphatase is also produced in bone, and bone illness might complicate the interpretation of irregular alkaline phosphatase exercise. The bile duct and pancreatic duct join on the duodenum, which is the primary part of the small gut. In situations where blood sugar supplies are low, the physique will preserve glucose for the mind, red blood cells, and kidneys. When this happens, the liver can produce an alternate gas supply from fat, often identified as ketones, by way of a course of referred to as ketogenesis. See your physician, however, should you experience unexplained weight loss, abdominal pain, jaundice, or different signs and signs that hassle you. Liver perform tests embody a quantity of different markers and should be interpreted with respect to every individual, together with their medical history, symptoms, and family historical past. If the liver is damaged or contaminated, it would release sure chemical compounds that can be detected throughout routine bloodwork. If the liver values show elevations further diagnostics are often required to substantiate the liver disease and get a diagnosis. In some instances, veterinarians might recommend no additional investigation if the liver values are solely slightly elevated or there’s a known cause (e.g. rising dogs will usually have elevated ALP due to the B-ALP a serotype produced by bones). Elevation in ALT shows there has been injury to the hepatocytes but that doesn’t mean there's undoubtedly liver illness as diseases outdoors the liver may cause elevated ALT also (pre-liver). Examples include heart disease, intestinal irritation, and extreme dental illness. elevated liver and pancreas enzymes Some slow growing tumors may be surgically removed, because the liver is able to regenerate even if a big portion is removed. Your veterinarian will typically carry out an initial blood panel to get a baseline for their values, and proceed to check them on the hour mark. Your pup could additionally be positioned on IV fluids, receive fluid additives to restore any deficits, injectable drugs for any symptom management, and any other remedies which may be recommended for their current state of affairs. ALP is an enzyme that is found in highest concentration in the liver and the bone. Side effects might include fainting, extreme bleeding and an infection, but these are rare. These are symptoms of your pancreatic functions beginning to interrupt down. If you lay your right hand across your stomach, that's roughly the size and form of your pancreas behind it.

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lindseyburgess37 · 9 months

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Carbohydrate Antigen Ca 19-9 Labcorp

After further evaluations, it was confirmed she had early-stage gallbladder cancer and was capable of take action. Lipase is a sort of digestive enzyme or "digestive juice." It helps your body digest fats. Most of your lipase is made in your pancreas, an organ situated behind the lower part of your stomach. Lipase can also be made in your salivary (spit) glands and in your stomach. For most types of tumors, a biopsy is the one sure way for the doctor to know if an space of the physique has a tumor. In a biopsy, the physician takes a small sample of tissue for testing in a laboratory. If a biopsy just isn't attainable, the physician might recommend other tests that may assist make a diagnosis. About 15 percent to 20 p.c of patients with pancreatic cancer are identified early sufficient that their tumor could be eliminated surgically. does elevated pancreatic enzymes mean cancer A level lower than 40 mg/dL is considered low (and is a threat factor for coronary heart disease), while a level of 60 mg/dL or larger is considered protective in opposition to heart illness. Thyroid issues can have an effect on cholesterol levels, with hypothyroidism often causing a rise in cholesterol. Thus, a Lipid Panel test may be helpful in managing thyroid issues by monitoring cholesterol levels and adjusting treatment as needed. High LDL cholesterol and triglyceride levels, or low HDL cholesterol levels, can lead to the development of atherosclerosis, which might cause strokes if arteries supplying the mind are affected. Further to this, the vast majority of research have assessed the utility of diagnostic biomarkers in sufferers with symptomatic illness, somewhat than as a surveillance or screening biomarker in the common inhabitants. Blood tests can consider the function of the gallbladder, liver, and pancreas. Levels of the pancreatic enzymes amylase and lipase can be measured. Blood tests can even check for signs of associated conditions, together with an infection, anemia (low blood count), and dehydration. A tumor marker referred to as CA 19-9 could also be checked if pancreatic cancer is suspected. Several attempts to improve the present diagnostic methods for pancreatic cancer and in flip its prognosis. Elevated levels of ALT and AST, for example, could recommend liver cell injury or illness. High bilirubin levels might point to impaired liver operate or a blocked bile duct. These tests additionally assess albumin levels, which mirror the liver's ability to supply proteins, and alkaline phosphatase levels, which might point out bile duct or liver injury. Changes in the quantity or percentage of various varieties of white blood cells can present insights into numerous well being conditions. An increase in neutrophils, for instance, might point out an acute infection, whereas a rise in lymphocytes could also be seen in persistent infections or sure types of cancers. The secretin stimulation test is a sort of pancreatic operate test that’s somewhat extra invasive than a blood test or stool test.

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l3irdl3rain · 2 months

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Merrill update under the cut, it’s long.

TLDR: she is very sick. Many of the things are treatable, but also she has cancer and I won’t put a 20 year old cat through chemo. So far she is showing minimal symptoms (sleeping more, less appetite). I’m hoping we can get the treatable things under control and we’ll have some good time left before the cancer really starts to affect her.

Radiologist said the “mass” that looked like it was on her heart is actually most likely just a bronchial cyst. I would need to go get a CT scan done to know for sure.

It’s not affecting her much yet, she just snores and when we were drawing blood she got a bad attitude and it made her wheezy. We can’t medicate for that yet bc the meds would upset her pancreatitis. So if we get the pancreatitis under control we can start medicating her for that.

Her bloodwork does show that she has some kind of cancer. I’m not going to chase after what kind it is because that would require a bone marrow test. Which is both painful and expensive. I’m not interested in putting a 20 year old cat through chemo, that would just be unfair to her, so ultimately it doesn’t make much of a difference what kind of cancer she actually has. It would just give me an idea of how quickly to expect things to progress. While that would be awesome to know, I don’t think it’s worth putting her through the testing.

We’re going to start by treating all the things we can and monitoring her for signs of any other issues. Definitely not what I was expecting to come from today. I figured there was a chance she’d have something small like hypertension or something, but definitely not for her to be falling apart all at once.

#my post #Merrill

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bruciemilf · 1 year

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Just Bruce quietly asking all of his kids to come to the Manor for dinner and when they all arrive, they notice Bruce sitting silently at the table trepidation and sorrow gracing his features. Alfred's already set the table and hovers over Bruce, anxiousness, and despair wafting off him in waves. They make it through the main course and dessert, before Jason snaps, scared by the disbelieving looks Alfred's been shooting Bruce the whole evening. Bruce swallows as though steeling himself for what's about to come out of his mouth next, he goes on to mention that during his most recent doctor's visit, they noticed something unusual with his pancreas and after further tests, they've confirmed it to be Stage 2 Pancreatic Cancer. It's like all the air has been sucked out of the room, they never imagined they lose him to something so......mundane. All of them, Bruce and Alfred included thought a bullet or a villain would be the one to finish off the Dark Knight. Not, an amalgamation of cells and it's like the sky's fallen down because a small part of them aren't ready to see their father slowly wither away.

#SO YOU CHOSE VIOLANCE HUH #WEL???? HOW DOES IT ENDDDD I NEED TO KNOW #bruce wayne

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dandelionsresilience · 3 months

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I’m not sure how reliably I’ll be able to keep up with it, but I’ve been wanting to start posting weekly or monthly Good News compilations, with a focus on ecology but also some health and human rights type stuff. I’ll try to keep the sources recent (like from within the last week or month, whichever it happens to be), but sometimes original dates are hard to find. Also, all credit for images and written material can be found at the source linked; I don’t claim credit for anything but curating.

Anyway, here’s some good news from the first week of March!

1. Mexican Wolf Population Grows for Eighth Consecutive Year

““In total, 99 pups carefully selected for their genetic value have been placed in 40 wild dens since 2016, and some of these fosters have produced litters of their own. While recovery is in the future, examining the last decade of data certainly provides optimism that recovery will be achieved.””

2. “Remarkable achievement:” Victoria solar farm reaches full power ahead of schedule

“The 130MW Glenrowan solar farm in Victoria has knocked out another milestone, reaching full power and completing final grid connection testing just months after achieving first generation in late November.”

3. UTEP scientists capture first known photographs of tropical bird long thought lost

“The yellow-crested helmetshrike is a rare bird species endemic to Africa that had been listed as “lost” by the American Bird Conservancy when it hadn’t been seen in nearly two decades. Until now.”

4. France Protects Abortion as a 'Guaranteed Freedom' in Constitution

“[A]t a special congress in Versailles, France’s parliament voted by an overwhelming majority to add the freedom to have an abortion to the country’s constitution. Though abortion has been legal in France since 1975, the historic move aims to establish a safeguard in the face of global attacks on abortion access and sexual and reproductive health rights.”

5. [Fish & Wildlife] Service Approves Conservation Agreement for Six Aquatic Species in the Trinity River Basin

“Besides conserving the six species in the CCAA, activities implemented in this agreement will also improve the water quality and natural flows of rivers for the benefit of rural and urban communities dependent on these water sources.”

6. Reforestation offset the effects of global warming in the southeastern United States

“In America’s southeast, except for most of Florida and Virginia, “temperatures have flatlined, or even cooled,” due to reforestation, even as most of the world has grown warmer, reports The Guardian.”

7. Places across the U.S. are testing no-strings cash as part of the social safety net

“Cash aid without conditions was considered a radical idea before the pandemic. But early results from a program in Stockton, Calif., showed promise. Then interest exploded after it became clear how much COVID stimulus checks and emergency rental payments had helped people. The U.S. Census Bureau found that an expanded child tax credit cut child poverty in half.”

8. The Road to Recovery for the Florida Golden Aster: Why We Should Care

“After a five-year review conducted in 2009 recommended reclassifying the species to threatened, the Florida golden aster was proposed for removal from the Federal List of Endangered and Threatened Plants due to recovery in June 2021, indicating the threats to the species had been reduced or eliminated.”

9. A smart molecule beats the mutation behind most pancreatic cancer

“Researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition.”

10. Nurses’ union at Austin’s Ascension Seton Medical Center ratifies historic first contract

“The contract, which NNOC said in a news release was “overwhelmingly” voted through by the union, includes provisions the union believes will improve patient care and retention of nurses.”

This and future editions will also be going up on my new Ko-fi, where you can support my art and get doodled phone wallpapers! EDIT: Actually, I can't find any indication that curating links like this is allowed on Ko-fi, so to play it safe I'll stick to just posting here on Tumblr. BUT, you can still support me over on Ko-fi if you want to see my Good News compilations continue!

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remindingpersephone · 11 months

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All of my mom’s tests have come back. She has stage 4 pancreatic cancer that has spread to her liver. She is too weak for treatment – but she doesn’t want it anyway. We meet with the hospice consultant this afternoon.

I’m compartmentalizing right now, being strong for my dad, making sure mom has everything she wants and is comfortable. At the same time, it doesn’t seem real. But it will become all too real soon enough.

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mischiefmanaged71 · 2 years

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The Love Hypothesis (2/22) - Stephen Strange X Reader

Summary: Y/N Y/L/N is a PhD student who wants to prove to her best friend that she has moved on and dating. With no way to prove it, she kisses the first man she sees, which ends up being none other than Dr. Strange, known as one of the most unapproachable and critical professors in the university.

A/N: AU! Stephen Strange is a Professor/Doctor at Columbia University and reader is a Ph.D. student (Reader - 28, Stephen - 34). Credits to Ali Hazelwood for the original story. This work is a piece of fiction. I have no ownership over anything, this is ff.

Pairing: Stephen Strange X FEM! Reader

Word Count: 4.5K

Series Masterlist

Y/N was a devoted third-year biology graduate, just as aspiring as another student among Columbia's illustrious cohort of Ph.D. students. It was a wonder she had only interacted with Stephen Strange on this occasion, despite his reputation within Columbia 's own biology department. Maybe that was a part of luck that worked in her favour, something that died on that Night.

A thought crossed her mind that she was fairly sure of - he wouldn't be bothered, nor interested enough to file a report on her. He didn't know of her and it was highly unlikely - she hoped this hunch was leaning towards correct, unless in the case where she was dead wrong and expecting a letter in her mail. In that event, she would be pleading guilty.

Alas, she had bigger things to focus on - like the neurobiology class she promised to TA for the semester, which was starting in two weeks. Or the fact, her project was reaching a dire point where she needed a rich lab to continue her research. Scrolling through he emails, considering all forms of work to pay it off until she came across an email in her inbox. A response from a Harvard professor

From: [email protected]

To: Y/N-Y/L/[email protected]

Subject: Pancreatic Cancer Screening Project

Y/N,

Your project sounds promising. I'll be visiting Columbia university in about two weeks. Why don't we chat then?

Cheers,

T P

Tom Pierce, Ph.D.

Associate Professor

Department of Biological Sciences, Harvard University

Her heart pounded in her chest as she stared at the email, slowing down to a slow skipping as she processed it. After months of trying, she finally had a response and from Harvard?

This was a good sign, right?

Forming her response, she sent him a detailed proposal of her proposal involving blood biomarkers and the list of her peer reviewed journals. If she was able to get in touch with a specialised cancer researcher at Harvard, this would be big for her project.

Heading for the break room with slightly lifted spirits, she pushed through the doors, only to in shock at the person standing in front of her.

"Natasha! You scared the shit out of me."

"Y/N." Her voice was low as she said her name, testing the waters. She never said her name like that. It was off-putting.

"How are you-"

"The other night." Natasha's face was serious as she stared at Y/N with an uncertainty painted on her features.

"-doing?" She cursed herself internally. This was not going as she planned.

"Dr. Strange."

She paused, "Yeah?"

Natasha stared at her, "Dr. Stephen. Strange."

She averted her gaze, "What about him?"

"I saw you together."

"Oh, really?" Y/N sounded surprised, putting off the fact she had seen Natasha.

"Yes. Here in the department."

"Oh, uh, I didn't see you, otherwise I would have said hi."

"Y/n/n. I saw you. With Strange. You know I saw you and I know you know that I saw you. That's why you've been avoiding me."

"I haven't been avoiding you. I've just been busy." She apologized.

Natasha gave her a 'bullshit' look that actually sent her heart rate spiking.

"You haven't responded to any of my texts in two days. We usually text every few hours."

"Something is up with my phone. The battery is gone. I've been too busy to fix it."

"Busy?" Her eyebrows raised, "Like too busy kissing Strange?" She pursued her lips.

Her eyes widened significantly, "You saw that..." Her voice trailed off, clutching the mug in her hand tightly.

"It was the strangest kiss I've ever seen. Pun, not intended. It was bizarre, no offence, Y/N."

Calm, just stay calm. She steadied her shaky hands.

"I don't know, I'd say there are a lot of weirder kisses. Like-take the upside-down Spiderman kiss-"

Natasha cut her off, "Y/n/n, you said you were on a date that night..." She slowly leaned in, "You're not dating Strange, are you?"

If Y/N admitted right now to Natasha that it was all fake and that she did it for her - all so she would go on a date with Steve, she there was a chance she might not trust her again. She wanted the best for Natasha, because she was the person that finally made her feel not so alone in this world. They'd been friends since first year undergrad and that meant a lot of time and understanding. And so, she did the right thing and moved along with her plan.

"What do you mean?"

"I mean that we tell each other everything, we talk every day and suddenly your ghosting me? You've never mentioned Strange before and now you're seeing him and I have no clue about it. It's a bit-I don't know...shocking to me." She sighed, "You know his reputation, right? Is this a joke? Do you have a brain tumour? Do I have a brain tumour?"

Y/N sighed. This was the problem with lying, you always had to cover your previous lies with more carefully constructed tales. Her heart was pounding in her chest as she stared at Natasha, unsure of what to say-

"Hey,"

The voice was deep, a low register in her ears as she turned to look at Dr. Stephen Strange standing at her side. The more stunning observation was the feeling of his hand on the small of her back. Her eyes almost bulged out of their sockets as she turned her neck to look at him, "Oh. Uh, hey,"

"Is everything okay?" He was talking to her in a low voice, almost as if they were alone and Natasha wasn't standing right there.

"Yeah." She nodded, "Yeah, everything is great. Natasha and I were just...chatting about our weekends." Causing Stephen to look at Natasha and acknowledge that she was there, nodding to her briefly. His hand slid lower to rest on her waist, but she wasn't sure from another perspective what that looked like.

"Nice to meet you, Natasha. I've heard a lot about you." Damn, how was he so good at this? So good at lying?

"It's nice to meet you too." Natasha looked shocked, covering it with a slight smile, "Um, I'm just about to leave so I'll see you later, Y/n/n. I'll text you..."

She was gone from sight before Y/N could form the words, leaving her with Stephen Strange and his hand that pressed into her waist.

"Is everything okay?" He repeated now that they were alone.

"Yes," she stared at him, unsure of exactly what just happened. "Yeah, I just..." Her face twisted in confusion.

"Thank you." She said, finally turning to face him.

"You're welcome."

"Did you hear what she said, about Friday?"

"Yes. That's why I..." He nodded, retracting his hand from her waist.

She nodded, "I also couldn't help but notice the lack of letter in my mail. No visit from the FBI either within the past seventy-two hours."

His lips twisted into a smirk, "Is that so?"

"Makes me think that maybe you haven't filed that Title IX complaint. Even though it's in your rights and I should probably stop talking right now. So thank you...for stepping in. You saved me a lot of trouble."

Stephen stared at her, unsure of her statement with a look he wore in seminars and workshops when people mixed up theory and hypothesis. "You shouldn’t need someone to step in for you."

Y/N felt herself stiffen, "Not as if I asked for you to do anything. I was handling it myself-"

"And I could tell it was going excellently." He deadpanned, "You shouldn't need to fabricate lies about your relationship status." He continued, "Especially not so that your friend and your ex can be together guilt-free. That isn't how friendship works."

So he had been listening.

"It's not like that." He raised an eyebrow in response.

"It isn't." She narrowed her eyes. "Steve was never my boyfriend and Natasha didn't ask me to do any of this. I'm not a victim in this...I just want her to be happy."

"At your own expense?" He replied, "By lying to her?"

"Well...she thinks we're dating."

"Wasn't that the point?"

"Yeah." She took a sip from her mug, the coffee now a lukewarm, "I'm Y/N Y/L/N, by the way. In case you were still looking to submit that complaint. I'm a Ph.D. student in Dr Xavier's lab-"

He cut her off, "-I know who you are."

She was stumped, staring at him for a moment, trying to imagine him rummaging through student profiles to find her. "Okay."

"I'm Stephen. Strange. I'm faculty in-"

She all but laughed in his face until she noticed his confused expression and paused to explain. "I'm sorry. I know who you are too, Dr. Strange."

"You should probably call me Stephen too."

Her eyebrows raised, "Oh, no. I couldn't." Grad couldn't call faculty by their first names, it was not supposed to be like that.

"If Natasha happens to be around." He continued.

"Oh, yes. That makes sense." She agreed, "I hadn't thought of that. If it's okay with you. I'm gonna head home, because this whole thing has been kind of stressful.

He nodded, "I'll walk you to your car."

"I think I'll be okay."

"In case Natasha is still around."

It was a kind offer, she was surprised. It didn't fit the so-called reputation everyone had denoted the Dr. "Thanks, but it's okay. I'll be fine."

He continued, "I'd feel better if you let me walk you to your car."

She mustered a smile, "I don't have a car." I'm a grad student living on campus and studying full-time, I can't afford one on less than thirty-thousand a year.

"Do you take the bus?"

"I bike. It's just at the entrance of the building."

He paused, opening his mouth and closing it. Y/N was late before she realised, she was staring at those lips. The lips she had kissed.

"There are no bike lanes around."

She shrugged, "I like to live dangerously. I have a helmet."

Setting her mug down, she turned to leave "I'll, uh, see you around."

He sighed, "Yeah. Okay."

***

"Is this a prank? Are you pranking me to get back at me for something? Where are the cameras?"

"It's not a prank. There are no cameras." Y/N adjusted the strap of her bag, "Although, speaking of cameras, you look good, especially for seven-thirty in the morning."

"Thanks. Last night, I did one of those face masks you bought me and I got a new mascara." Before she could ask, Y/N nodded in understanding. Steve and Natasha worked on the same floor, making the chances of them interacting much higher. She hid a smile.

"Okay. So if this isn't a prank, then there must be some other reason I'm missing."

"Oh my god, are you in trouble? Do you need help because I have ties with law enforcement and-"

"Natasha." She gripped her shoulders, "I am fine. I'm not in trouble. I just went out on a single date with Strange."

Natasha's face scrunched, dragging her friend to sit on a bench, "Do you remember last semester when you were sick and I nursed you back to health?"

"Yes, I remember it vividly."

"Well, that's a reminder that I am here for you. No matter how many gross things I need to get through to make sure you're okay."

"Thanks, Nat. Not for the slightly insulting comment, but the support is much appreciated."

"We're a team. You and I. And Sam, when he's not so focused on other things. So is Strange secretly an alien infiltrating humanity or-"

"Oh, my god! It was one date!"

"I'm just confused. I'm trying to understand." Natasha pleaded.

"I know but-there isn't anything to understand, Nat. I went out with the guy once."

"But, why? You're beautiful and smart and you have excellent taste in movies, why would you go out with Stephen Strange?"

She was stumped for an answer, "Because...he's nice."

"Nice? Stephen 'ass' Strange?"

"Yeah...he's nice and kind...and he understands me." Natasha raised her eyebrows in disbelief, "He's a nice asshole."

"Okay, so you went from dating someone amazing like Steve to going out with Stephen Strange."

Perfect. This was the opening she needed to move onto the next subject

"I did, and happily because Steve and I never clicked. I never cared about him that way. It wasn't difficult to move on. Which is why, Nat, you should accept his offer and go out with him. I know you like him and I'm so sure or his feelings for you. You should do it for yourself. You deserve it."

"I don't know. Maybe..." Until her phone beeped, "Crap. I've got a mentoring meeting and I need to run two assays. Want to meet for lunch?"

"Can't. I have a TA meeting." Y/N smiled, "Why don't you see if Steve is free?"

Before she left, Nat turned once more with her bag in hand, "Is he blackmailing you?"

A laugh bubbled from her throat, "What?"

"Is Strange blackmailing you? Does he know that you're weird and you're always freakishly cold?"

"What? No. He is not blackmailing me." She shook her head.

"Okay." Nat raised her hands in defence, "I had to check."

"It's flattering you think Strange would go to these lengths to get me to date him."

"You're beautiful and smart. Anyone would be lucky to have the privilege, Y/n/n."

***

Steve was acting weird around Y/N that day when she finally walked into the boarding room. He looked at her from his desk three, maybe five times. This was more attention he paid to her than when they were dating. Looking back at her email, she forwarded the response to meet up with Dr. Pierce to chat about her screening project.

Eventually, another fourth year walked in and sat next to Steve, whispering and looking over at her table. She paid no attention, focusing on the timely response from Dr Pierce, informing her he was on sabbatical for the moment and was in fact, going to be there in a few days to talk with a Columbia collaborator. She had a few days to convince this Professor of her project and it's significance. No pressure.

Suddenly looking up, she sensed more eyes on her and recognised the group eyeing her on the spot. A seventh year she had never talked to before spoke up, "Hi, Y/N."

"Hi," she replied, unsure of the attention.

"How are you?"

"Great,"

"That's good." He muttered.

"And you?" Trying to appear normal

"Good."

Her eyebrows furrowed in confusion as he walked off toward. Things got weirder from there - namely when Dr. Xavier appeared and asked her if there was anything she wanted to tell her. Another grad let her use the PCR machine first, people literally opening doors for her. It was a day taking a disturbing turn.

"You sneaky woman." Sam muttered, "I've been trying to contact you all day."

"What for?" she looked up from her bench, “I forgot my phone at home."

"I cannot believe it." he shook his head.

"Believe what?"

"Believe you."

Her eyes narrowed, “What are you talking about exactly?"

"I didn't believe it at first. I thought we were close friends." he crossed his arms.

"We are." she nodded, but he continued in spite of this.

"Good friends."

"Sam, is there a reason for this?"

"Clearly we aren't friends then if I had to hear it from Stella, who heard it from Jess, who heard it from Steve, who heard it from Natasha-"

"Hear what?"

"I'm done. I'm changing my Netflix password. You can fend for yourself."

"Sam, what did you hear?"

"That you're dating Stephen Strange."

Oh no.

***

Y/n had never stepped foot in Strange 's lab before but today would be different as she pushed the doors open and eyes fell on her. She stiffened and found him, awkwardly moving inside.

"May I speak with you in private for a moment, Dr. Strange? It's important." She smiled weakly. He nodded, handing back the paper to his student and lead her into an empty office.

"Everyone knows." She blurted out.

"Are you okay?"

She shook her head, running a hand down her face, "Nevermind that. Everyone knows. About us."

"Us?"

"Yes. Us. Dating-not that we are, but Natasha clearly believed so and she told Steve, who told everyone. Now everyone knows, but there isn't anything to actually know. As you and I...know."

"...when you say everyone?"

"I mean everyone. Those people. The other grads. Cherie, the department secretary. She totally knows. Dr. Xavier. They all think I'm dating a professor."

"I see."

"I'm sorry this happened. I wasn't thinking and now we're in this- I just don't know why Steve would tell everyone."

"Why wouldn't he?"

"What do you mean?"

"A grad student dating a faculty member seems like an interesting piece of information to share." he gestured. "It's no wonder he talked."

"It isn't that interesting, per say. Why would he be interested?"

"Someone told me gossip in this department is the worst." He pointed out, a hint of a smirk.

"Alright, alright. Point taken, Dr."

"This is-a mess. We need to do something before-" she paused, "We need to tell people it's not true. Except they'll think I'm crazy or they won't believe it and then-"

"What would Natasha and what’s-his-face do, huh?" His expression hardened.

"What?" She breathed.

"What would they do if they found out? Won't they feel bad you lied to them about dating if they were together?"

"Maybe," she shook her head, "I don't know."

"Are you going to tell her the truth?"

"I don't know. I can't. Not now." She looked at him, "Maybe we can tell people I broke up with you."

"Flattering." He lifted his brows.

"Fine. You broke up with me." She offered.

"Because that sounds credible." He replied drily. She wasn't sure what to take from that.

"Mutual breakup?"

"Sounds good." He nodded, folding his hands.

"Really? Great-"

"We could ask Cherie to put in the department announcements and everyone should know soon." He smiled, tilting his head.

"Huh?" She paused, standing in front of him.

"A public announcement would be better, no?"

She huffed, "Okay, fine."

He studied her with a calm look that stumped her; far from the expectations she drew from Stephen 'Ass' Strange. "If what bothers you is that people are talking about you dating a professor, the damage is already done. Telling people otherwise won't change what they think."

Y/N clicked her tongue against her teeth and held her arms to herself in exhaustion. "Okay. If you have any better idea of how to fix this, I'm all ears-"

"You could let them think what they want."

She wasn't so sure she heard him correctly.

"You can let people go on thinking we're dating. It solves your problem and you don't have much to lose..."

Y/N raised her eyebrows in response, "From a reputation standpoint, things cannot get any worse from here on out."

She was completely out of her depths.

"Seems like a win-win to me."

It seemed more like a lose-lose, really.

"For how long?"

"Whatever works best, I guess."

Her eyes narrowed in confusion, "Are you not...I don't know, married or something?"

He must have been in his thirties. He has a fantastic job, clearly smart and attractive looking. He was also built. Yeah, he could be moody and a bit critical, but a lot of women could look past that. Some might even like that.

"My wife and twins won't mind."

Her eyes but bulged out of her head at his comment. Something twisted in her stomach, threatening to throw up everything from her body. A wave of heat passed over her as she watched him. "Oh my god -"

"Kidding-"

"I had no idea-"

"Y/N, I was joking. I'm not married. No kids either."

Her eyes hardened, "Dr. Strange, that is not something to joke about-"

He interrupted her, yet again, "You should really start calling me Stephen. Only normal for people who are dating." He wore a sweet smile in response. Sweet smile twisted with mischief, that was for sure.

"What do you get out of this?"

It was his turn to be confused, "Out of what?"

Y/N paused in thought, studying Stranger's face before it crossed her mind. Stephen watched her tilt her head and a snort left her. "Pretending to date me. What's in it for you?"

She watched as Stephen opened his mouth and for a moment it looked as if he was going to actually say something of importance before he averted his eyes and leaned against the desk. "It would help you out." He sighed, "I also have my own reasons."

"And what are those?"

He was curt, "Reasons."

"If it's criminal, I'd rather not be involved if that can be helped."

He smiled in that way that sent her heart skipping a beat, "It's not."

A huff left her mouth as she scrutinized him for answers, "If you don't tell me, I'll just assume you're affiliated with something nefarious. Like arson. Or kidnapping."

He appeared focused, watching her as a beat passed between them with each tap against his bicep. He stared for a moment longer before he relented, "If I tell you, not a word can leave this room."

"I think we can agree that nothing said in this room can ever be repeated for a number of reasons." She relaxed her face, sensing the tension lingering there.

"Point taken." He agreed, pausing for a second before he sighed, "Okay. I'm considered a flight risk."

"Flight risk? Are you planning on travelling or-So it is something criminal?" She moved slightly forward, crossing her arms.

"What? No. The department suspects I'm making plans to leave Columbia and move to another institution. Normally, I wouldn't be bothered by this sort of thing, but the university has decided to freeze my funds."

Realisation washed over her, "Oh. Can they?"

"Up to a third of them. The reasoning is that they don't want to fund research and further the career of someone they believe is going to leave."

"But if it's only a third, surely-"

"It's millions of dollars. Money I had marked for projects I planned to finish within the next year. Here. Which means I need those funds soon."

Finally, it all made sense.

"Why do they think you'll leave?"

"There's a number of things. The most relevant? I was awarded a grant a few weeks ago - a very large one - with a scientist from another institution. They've tried to recruit me many times and Columbia sees the collaboration as an indicator of my willingness to accept." He continued, "More generally? I've been made aware that appearances matter to the department, seeing my lack of roots as a want to flee Columbia."

"Roots?"

"Most grads will be done in the year. I have no family here. No wife. No children. I'm currently renting and I...I'd have to buy a house to convince the department otherwise. Being in a relationship...that would really help."

"Alright." She nodded, gesturing, "All of that made sense, but have you considered getting a real girlfriend?"

"Have you considered getting a real date?"

She halted, nodding "Touché."

Y/N could have laughed at the situation as the man she should have been frightened of, or at least put off by, was now the only person who knew of her worst mistake. It was intimidating, but also liberating now to at least know of an equal opportunity here.

"It would be complicated."

"What would be?"

"Pretending to be a couple." she clarified.

"It would be complicated to make people believe we are dating?" he pressed his lips together.

"It would be difficult to make it convincing for a long period."

"It'll be fine as long as you say hi to me in the hallways and stop calling me Dr. Strange."

"People who are dating don't just say hi to each other." She argued.

"And what do people that are dating do, exactly?"

Okay, so maybe she wasn't an expert on the topic, but she was dedicated and determined, if anything. A bookworm and a lover of romance, so the fictional world would have to do. They had things in common, what with being in the same department and academia.

"They do activities together. Like going to the movies, having picnics and getting dinner."

"You could just tell Natasha we went to see a movie. Sounds like she would take care of the rest and let everyone know."

"Actually, it was Steve. Let's agree to blame Steve for everything." She blinked, relaxing her hands on her hips, "People who date talk - they know things about each other and they hug. They kiss."

Stephen, leaned against that desk with his arms crossed against his chest in that way that flexed his arms, pressed his lips together to hide something. "We could never do that."

A heat flushed over as her mouth fell agape, looking to the back of the room. She could feel his gaze on her and she sighed, an apology dying in her throat. "Glad to know my embarrassment is amusing to you."

"I wouldn't say you are 'amusing'."

"No, but you are enjoying this." She concluded.

"To a certain degree."

Her eyebrows raised, hiding her flush behind a blank expression, lest she fall over from an unassuming tease or remark.

A worn laugh left her as she sighed, falling into her hands as she rubbed her eyes tiredly, "This is the worst."

Stephen was smiling, it was cute and revealed dimples. It made him more handsome. "Yep."

"And it's my fault." she trailed off, closing her eyes.

"Pretty much. Although I'll admit, I did kind of encourage Natasha yesterday. But yeah, it is mostly your fault."

Her eyes widened as she suddenly thought of something, "Wait, isn't there an issue with you being faculty and me being a graduate student?"

He tilted his head, the smile leaving as he thought over it, "It wouldn't look great but there shouldn't be an issue since I have no authority over you. I can ask around."

It was an epically bad idea, but after the mistake she made and the lie, it would be messier than what this entitled. "Is it alright if I think it over?"

"Of course." He replied calmly. His tone was stumped her yet again, unlike the Professor many had told her about.

Before leaving, she turned to him "And thank you, for understanding. And for offering, Stephen." His name came out like an afterthought as she tried it out.

"No problem, Y/N." Slightly smiling at the end as she took her leave.

TAGS:

@goldencherriess @severuined @thewinterpoet2 @pasta-warlord @typical-bistander @judig92 @captainbarness @gaitwae @sleutherclaw @angstsfordays @mavsketch @mando-is-the-way @samisubi @liar-liar13 @evelynrosestuff @stanny-uwu @colorfuly-blog04 @frostandflamesfanfic

#stephen strange x y/n #stephen strange #stephen strange x reader #doctor strange #doctor strange x y/n #doctor strange X reader #the love hypothesis au #the love hypothesis #marvel #Marvel x reader

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zionchubby14 · 4 months

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I wasn't sure if I was going to make a post about this, but this is something I feel like I need to do, especially for those who know and care about me (I know, people care on here? That's crazy.). I'm definitely going to struggle typing this all out, but...here it goes.

_____

So over the past month (and quite possibly earlier), Mom has been dealing some abdominal pain that radiates to her back. The pain would be so bad that it would cause her to throw up at times. She barely ate and slept while this was going on. On January 6th, things finally came to a head and we made the call to take her to the hospital.

When she first came in, she was diagnosed as suffering from pancreatitis (for those who don't know, it's inflammation of the pancreas that, if left untreated, can cause a high amount of pain and nausea to the person. There's two types of pancreatitis: acute, which is very treatable and will go away after a while, and chronic, which will last a lot longer and hurt more). They were able to treat her and she felt better for a while, discharging her after 3 days. When they released her, they wanted her to get a endoscopy test done up at a hospital in Royal Oak. With neither Mom or I having a car, this was difficult for us to do. But we would come to know why soon enough.

Mom came home and for a day or two, she seemed fine. She ate well and was able to sleep soundly, which I thought was the important thing. But the pain and nausea eventually came back with a vengeance We tried every the hospital doctors had told us: heating pads, soft to liquid diet, pain patches. Nothing was working. Her primary care doctor even had her go on some antibiotics and a stronger pain med than she had, but nothing seemed to help matters. We took her back to the hospital this past Saturday, January 20th.

When we initially got there, after they had done a CT scan on Mom, they said that the pancreatitis was gone. But what was left was a mass on her pancreas. Scared and unsure as to what it may be, they admitted her and has been in the hospital since. On Tuesday, they took her to the University of Toledo Medical Center for the endoscopy and see what the mass might be. They did the scope and drew fluid from the mass for testing.

On Wednesday, we get the news that it is cancer. More precisely, metastatic pancreatic adenocarcinoma. In layman's terms, it's Stage IV pancreatic cancer, not curable.

I could not believe it...

We don't really know how long she may have left, but the rough and harsh estimate is less than 6 months...

Needless to say, I broke down, not in front of Mom or my brothers (who have been with Mom and I throughout this whole thing).

I can't imagine being here on Earth without Mom and I'm somehow going to have to figure out how to...I panicked and wanted to run away...a moment of weakness...

I don't know what will happen between now and the inevitable day, but we all agreed that we're going to try and make the most out of the days she does have left. I know that there will be bad days ahead, and there'll be good days as well.

But it's tough, knowing that the last few years I've been taking care of her (and complaining about her behavior, which is making me feel guilty about, now that this is happening) and it's going to come to an end.

_____

I know this isn't the greatest of things to post on here, but I needed some therapeutic way to get some of the emotions I am feeling right now out and to inform you all of what has been going on. I thank you all for the thoughts and positive vibes before and coming in the future. It's going to be a rough time ahead and I hope you will all bear with me in the meantime.

I love you all.

#therapeutic post #needed to get things off my chest #fuck you cancer!

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ofhouseadama · 1 year

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Bella Adama ??? — November 24, 2022

Bella, thirteen to possibly fourteen years of age, passed at home on Thanksgiving night. Originally from parts unknown and returned to the pound no fewer than three times, she lived the best life a goblin disguised as a dog could ask for after being rehomed to the nanny (Leah) in the aftermath of a divorce. She is survived by her caretakers and moms, Leah and Emily Adama, in addition to her sister Lady Adama, her beloved Not-Mom Not-Dog, Mira Adama, her favorite auntie and dogsitter, Layla, her begrudging grandfather, Lou, and doting grandmother/insurance agent Jody. She is predeceased by her grandmother, Sharon, her sister, Luna, and the many birds that she hunted and killed over the course of her lifetime.

Rumored to have been a criminal turned into a dog as punishment for misdeeds, Bella never completed the requisite number of good deeds to turn back into a human. Instead, she extended her sentence as a mutt through endless garbage crimes, destruction of property, numerous instances of tearing curtains off the wall and placemats off of tables, and more than one noise complaint from the neighbors. On one notable occasion, she rammed her stubby little body repeatedly into an HVAC duct under the house, tearing it from its fittings and sending it crashing to the ground. She escaped the backyard more times than anyone may ever know. She was a bully and a terror, opinionated and forceful, and made sure no one in the house ever missed a meal. Her mothers regret never getting her DNA tested to see what mix of breeds would result in such demonic behavior. She was the worst.

Over the course of the eleven documented years of her life, Bella never met anyone she didn’t want to make into a friend. This included every PetSmart employee, vet techs, contractors, neighbors, visitors, and the mail carrier. Unfortunately, Bella never developed a single manner or sign of good breeding. But those who could tolerate her absolutely unhinged idea of affection could rely on her to headbutt them repeatedly should they dare stop petting her before she was done. By February 2019, she was fed up with only having one mom to give her attention, and threw herself into Emily’s lap during her first visit to South Carolina and acted like a normal dog one whole time. Leah was so shocked at the sight that she immediately called her father. Leah and Emily would wed later that year, Emily being successfully suckered by Bella’s con.

The last few years of Bella’s life, she enjoyed constant snacks and affection. When the COVID-19 pandemic hit, both Leah and Emily started working from home. The conditions of the pandemic brought her precious Not-Mom Not-Dog into the home as well, and between the various insomnia episodes and wfh schedules of Leah, Emily, and Mira, Bella was never without a human to accost into giving into her will.

In the end, despite facing many health scares (many eaten and vomited up socks and plastic grocery bags, garbage heists, containment breaches, a chronic pancreatitis diagnosis, possible liver cancer, and one notable incident with an entire roll of Christmas ribbon which resulted in surgery) over the yawning chasm of a decade of chaos and bad behavior, death came as a friend. She spent her last weeks pampered at home, and passed in the laps of those who loved her the most.

There will never be another dog as perfect as she was.

In lieu of cards or flowers, please make a donation to your local humane society or give your dog a piece of cheese.

#death cw #pet death cw

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tsuchinokoroyale · 1 year

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Wait what, give us the cancer cell fun facts king

Sure thang 😎 Before I get into pancreatic cancer, let’s talk about lumps. One method of early tumor detection everyone should be periodically practicing is feeling yourself up for lumps. You should really get to know your testes if you got ‘em and it’s my scientific opinion that everyone should be feeling up their own chestes anyways, but it’s also good to do it on purpose to detect any abnormality as soon as possible.

What’s in a lump exactly? A healthy human body is a mix of many different cell types, and tumors are no different. I’m going to mostly correctly breakdown the various cell types as cells that do things/Epithelial cells, the in-betweeny/structurally important cells/Mesenchymal cells, and the blood cells where you got your cute lil red blood cells and immune cells. The interaction of all these cells forms something like an ecosystem, which we refer to as a microenvironment. Solid cancers arise from cells in tissues that lose the ability to die and/or gain the ability to keep dividing, so it makes sense that a lot of cell types present in the healthy microenvironment would be present in the tumor microenvironment/TME. However, the function of these cells have been found to be radically altered by the cancer cells in order to promote tumor growth and survival.

The pancreatic cancer lump is notable for two reasons: it is HARD and it is almost entirely made up of non-pancreatic cancer cells, with up to 90% of the tumor volume being non-cancer cells. A healthy pancreas is made up almost entirely of acinar cells which secrete digestive enzymes into the intestine, with some specialized regions for maintaining blood sugar levels. The pancreatic cancer TME on the other hand is an absolute circus. The lump is hard because the cancer has rewired certain mesenchymal cells to continuously churn out structural proteins, creating this densely fibrous netting which leads to drug permeability issues. There’s an influx of immune cells that should be performing anti-cancer duties but have instead been rewired to suppress immune responses. In order to prevent auto-immunity, the body’s own immune system targeting itself, there are various mechanisms by which the immune system will propagate a STOP response. The cancer cells adopt this process, secreting signals to override any productive immune response and push immune cells to suppress immune responses instead. As much as I’d love to get into the specifics and controversies of myCAFs, iCAFs, MDSCs, TAMs, Th1/2/17/regulatory CD4 family, and my poor downtrodden CD8 T cell babies, this post is already pretty long and I’m retired anyways 😮‍💨

in case anyone feels like reading the actual science version of this

#asked and answered babey!#it’s been like 2 years since I’ve thought about this stuff but I guess it’s like riding a bicycle #once you spend 5 years memorizing the intricacies of the pancreatic cancer TME you just never forget it 🤔

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xcestlavie · 5 months

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" I'm all talk with a thorn in my side I got a real big heart that I'm willing to hide "

full name . alexander oliver morgan nickname(s) . alex , ander ( exclusive to his mother ) , oli ( brothers ) age/birthday . 28 06/23 ( cancer ) gender/pronouns . cis man he/him place of birth . bristol , united kingdom current residence . frog hollow , cape may sexuality . pansexual / romantic

occupation . actor

aesthetics . half-finished mug of coffee , the smell of rain in the air , and unanswered texts .

physical .

height . 6'0" build . lean hair color / style . brunette ( with a tendency to dye it blonde ), goes for the unkept stylized mess look. eye color . blue face claim . tom blyth

mentality .

positive traits . creative , loyal , charming , protective . negative traits . distant , flirty , jealous , smart ass . most of his personality is an act , a homebody by nature he keeps his circle small and tries to keep his head low . expressing himself isn't something he does well and he lashes out if his feelings are hurt or his trust deemed broken . he can be quick with a joke and can sometimes flirt himself into awkward situations most of which he doesn't know how to get himself out of . willing to take little jabs at noa if for nothing else just to see them get frustrated he thrives on the chaos and bickering between them ( won't admit to being jealous of anything they have going on , has their back no matter what , lowkey feels miserable that he's pretty much riding they’re coattails , actually secretly adores them ( but i didn't type that ) ) .

biography .

( tw . cancer mention & parental death )

born in bristol to an already large family alexander oliver morgan is the youngest of five boys, the closest sibling age-wise to him being five years older and the oldest being ten years older than alex. he was a mommy's boy, if she was out and about the small boy was bound to poke his head from behind her. when he was seven his father was diagnosed with an aggressive form of pancreatic cancer and he lost his fight with it a year after that.

despite not being exceptionally close to his father it was still his father and the young morgan boy found escapism in movies, the movies he watched during that point are what had him hellbent on carving a path for himself in the industry. he begged his mom for classes and took every opportunity he could to preform on a stage. from eleven to eighteen he tried at least making a local name for himself before he started throwing his net out in different ways. it took it a moment but he got a bite, but when he was twenty he found himself flying to america for the first time for a screen test. life turned into a whirlwind and somewhat nauseating situation of pressure, he didn't know what to expect from the show but it wasn't quite that, and cameras on him at all times was not something he was used to nor did he like all that much.

there came the time when the show ended and it was a bittersweet thing. alex carried a lot from that show his first acting credit, a fake relationship, and a better way to grasp at fame no matter how small or big. he'd done things while working on the show but free of it he was able to move and pursue bigger projects, the most recent one being filmed in france. it's somewhat of a funny thing deciding to set up home in cape may. but it was some place out of the way for prying eyes and it was by a beautiful beach.

head canons .

loved playing football as a child. wanted to do rugby but it was shot down by his mother. likes music and spends time - he's not willing to share just how much time - making a playlist for each character he auditions for or portrays. still a huge mama's boy. besides english, he knows enough french to get by, and enough japanese to introduce himself. lowkey romantic. he romanticizes the idea of romance more than anything. lowlowkey nerd. good book-to-movie adaption and superheroes make his little heart happy. in interviews he says he doesn't have any form of social media but it's a lie, he has a secret accounts on all the social media platforms that matter (save for facebook. he really doesn't have one.) under the username bristolssoliolioxenfree. the accounts are private and he just uses them to lurk.

the show he got his start on was very friend's coded.

totally chose frog hollow to buy a house because it reminded him of the play a year with frog and toad.

extras .

playlist . pinterest . connections .

#cape.intro #tw.cancer mention #tw.parental death #&& . amorgan ; let’s call these the golden years ( answered . )#&& . amorgan ; call to leap ( meme . )#&& . amorgan ; i swear i’m trying ( task . )#&& . amorgan ; periodically experiencing the human condition ( musing . )#&& . amorgan ; words don’t always work ( thread . )#&& . amorgan ; the boyish charm he exudes ( visage . )#&& . amorgan ; the torture of small talk ( text . )#&& . amorgan ; you know all the words ( music . )#&& . amorgan ; viral mess turned dreams into an empire ( ft . noa . )#&& . amorgan ; burn all the rumors about you ( study . )#mostly word vomit and bare.

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itchyeye · 1 year

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I will forever be baffled about what a turn the writing took. I swear, for the longest time, I felt SO in sync with every choice, excited for what it was setting up. And then nothing came out of it. For example, it felt like a given to me that Jon would end up visiting Elias in prison, because surely, the set-up requires and guarantees it!

Though the worst example for me is the conclusion for "Jonah" in the Fanshawe episode, which was "Well, I guess he was evil all along actually." And that's literally it, never challenged in any way again. Jonah's just evil.

Mind you, I'm not saying Jonah shouldn't be evil, I like him evil. But I thought that surely, Jon would find out more about him, things would get more complex and nuanced. Nope, he's just evil, glad we settled that with 70 episodes to go.

yessssss i absolutely spent s4 WAITING in antici - [frank n furter pause] -pation for when jon would finally confront elias in prison and they would test the hell out of those standard issue handcuffs

looking back on it, as much as i hate that they were separated for so long, i've resolved the agony with the hc that elias knew that jon's beholding powers were becoming too powerful for them to occupy the same space

this is a man creature that knew unprompted that daisy had only ever successfully gotten drunk once in 2006, and that london was 607 square miles, and that basira's year 8 pe teacher died of pancreatic cancer

knowledge was forcing its way into his head at increasing and alarming speeds, he felt statements call to him and he felt statements being pushed away from him, there was no way elias would be able to keep his identity hidden with how powerful his archivist was becoming [HORNY GRIP]

i agree with you partially re: the fanshawe episode

i think the fact that jonah wasn't explored more as a character is just.... it's just poor craft. it's bad storytelling. it's stacking guns up floor to ceiling and then leaving them untouched on the wall.

but i looooooove jon's little reflection on jonah in that episode (see my and @doomsayings ' exchange in the notes here)

also god ugh i know.... 70 episodes to go.... jonny and alex made a joke in the s3 q&a that oh well of course elias is in prison so that's the end of his arc :) bUT IT WASN'T REALLY A JOKE WAS IT, BOYS???? YOU JUST. STOPPED WRITING ABOUT HIM AT ALL.

#[💌] asks and replies #anonymous

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blairwitchapologist · 1 year

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the have to run so many tests on my grandpa that we won’t know for sure if it’s pancreatic cancer or not until like over a week from now and it’s just like. if you think i didn’t care about my job before, now i REALLY can’t make myself care about it lmao

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bpod-bpod · 1 year

Video

Keep Still

Trying to stop cancer spreading is like catching sand in your hands. If any of a tumour’s countless cells break out and start anew in another organ, the consequences can be deadly. Immobilising them altogether would help keep control of the problem. A study examined the potential for low intensity ultrasound – high wavelength sound waves like those used in antenatal scans – to keep cancer cells in their place. The researchers subjected a layer of pancreatic cancer cells to continuous ultrasound for 20 minutes, and watched as the population of cells migrated to repair a wound (video, bottom, compared to untreated cells, top. Cells are coloured according to their direction of travel to help analyse the results). They found that movement was greatly reduced even 2–3 days later. If this approach works in future tests in animals – and eventually people – it could provide an affordable, non-invasive way to stop cancer spreading.

Written by Anthony Lewis

Video from work by Itziar González and colleagues

Group of Ultrasonic Resonators RESULT, Institute of Physical Technologies and Informacion, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain

Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Frontiers in Cell and Developmental Biology, January 2023

You can also follow BPoD on Instagram, Twitter and Facebook

#science #biomedicine #ultrasound #cancer #oncology #metastasis #pancreatic cancer #cell migration

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smol-tired-binch-blog · 8 months

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Smol's Demonverse: How The Hell Does Hell Work?

Hello, this is the post with my outline of different demon types in my Demonverse plus a basic idea on how Hell works! Now admittedly, it may not be the most original or polished thing; this is basically my playground where I plonk any OC designs that aren't fandom related or connected to my Big Project/any potential projects in the future. Edits may be made, but for now, this is the basic gist of it. Should also give you an idea for what I mean when I talk about Viceroys and stuff in my OC ref sheets! It's going under a read more because fuck me there's a lot to get through. Enjoy <3

How The Hell Does Hell Work?

Hell is where sinners go when they die. That much is obvious. But what constitutes a “sinner”? There’s a surprising amount of wiggle room in terms of how much ‘sin’ someone can commit and still go to Heaven. It’s a matter of a) intention, and b) consequence. How much malice is behind an action and how large the impact of the action all adds up in the end. So, say someone found the cure for syphilis and pancreatic cancer, should be a one way ticket to Heaven, right? However, if they found these cures whilst trying to find a way to eradicate autism and gay people or then patented their treatments to sell them at extortionate prices, then you’re headed Down There. Similarly, someone who ends up poisoning a bunch of children because they, say, tried to make some delicious cakes and sweets for the kids and had no idea that a certain ingredient was toxic or something the kids were allergic to, and felt genuine remorse for their actions, it’s not actually a guaranteed trip to Hell (although those consequences must be paid for. Maybe some Celestial Community Service).

Even then, there’s some confusion. If Hell is meant to punish sinners, then does that make demons good? Again, not so simple. Lest we forget, temptation is a big part of things. It’s easy to be good if the option to be bad has simply never presented itself in your life, so a true test of character is to be presented with the sinful option, and see how one handles it. Again, does this make the demon offering temptation a good person who wants to aid in your personal growth? Not necessarily.

There are several types of residents in Hell, which can be classified as follows:

Sinners

Sinners are people from Earth who have died and gone to Hell. Mortal souls. When one arrives in Hell, most tend to experience some change in their appearance, influenced by their life, their reason for being here, and their beliefs. One thing that always happens for some reason, is that they end up with three fingers as opposed to the normal four. No one is entirely sure why this happens. Other changes often involve skin changing to pure white, black, or some other colour, changes in eye and hair colour, as well as hair length. Some people gain wings, tails, horns are also incredibly common but a rare few end up without. Some gain more animalistic qualities such as claws, fangs, tails, animal legs, even full anthropomorphisation.

When a Sinner arrives in Hell, they are often brought to a Higher Demon and assigned living space. Life in Hell is similar to life on Earth, in that there are cities and towns full of businesses and restaurants and the like, but everything is run by the worst people humanity has witnessed. It’s a tough life to be certain, made even worse by the assigned torture. The Boss quite quickly figured out that torture is much more effective when the victims are given a break. So, a schedule is laid out; sinners are allowed time to settle into their new life, until at some point another demon will come and collect them for a certain amount of torturing, before being let go, and the process repeats itself. Some of the Higher Ups have found that they needn’t bother torturing everyone, as it turns out a lot of Sinners will gladly hurt each other for free. However, nothing quite beats a paid professional, and so, certain Sinners are offered official work in Hell, either paperwork and classification, or torture, or temptation.

They’ve also been placed into different Districts, usually based around their main Sin/crime, although there can be some overlap as people are rarely guilty of just one Sin. Another method, therefore, is to place them in a neighbourhood surrounded by fellow Sinners, say, those who mostly committed Greed, but then a professional from the Lust district will come collect them for torture at some point. Honestly, just living another life surrounded by reminders of yourself is hell enough for some.

Embodiments/Overlords

Embodiments are Hell-born demons or spirits that were incarnated as mortals to become the embodiment of a certain sin. These are the ones who get to run their own little areas in their Districts, similar to a crime family (except for Narcolep, he has others do it for him). They don’t run the entire area, they report to Higher Ups, but they hold a lot of power over the lower demons. Funnily enough, in the Lust District, more Succubi, aka Tempters, are Overlords than Embodiments (I guess people respond better to a sexy demon than a slobbering incel who’s never seen a tit that wasn’t from anime)

Tempters

Tempters are often Hell-born demons whose purpose is to tempt mortals into sin and see if they can bring them over to the Dark Side, but mortal souls can also apply for such a role. They’re similar to Embodiments as chances are, they indulged in a particular Sin so much that they’d love to do it as their job. These have their own subroles, the most well-known being Succubi/Incubi and Dealmakers.

Succubi

Followers of Lust, these Hellborn demons rely on either being summoned to Earth by mortals messing with dark magic for a quick lay, or make their way to Earth to tempt mortals personally, getting them to sign over the soul in exchange for carnal pleasure. The latter is more challenging but therefore sometimes seen as more ‘fun’. The most powerful Succubus is known as Demistress, with her six daughters destined to follow in her steps. Succubi feed upon the carnal energy of their claims, but when it’s time to collect the soul, it’s either a matter of the mortal dying naturally or having agreed upon a certain timeframe for their soul to be collected, at which point, the soul descends to Hell, and the Succubus who claimed it has personal control/say over it. This often amounts to being the one to torture their claim, or continue their carnal relationship in Hell. Many Succubi and Incubi have gotten themselves some nice little harems from this.

Dealmakers

These demons have the qualifications to go to Earth and forge contracts with mortals and claim a soul for their District. They’re often independent contractors, and set up shop on Earth rather than residing in Hell, though some don’t mind the commute. They’re often known as Crossroads Demons, but can decide their base of operations for themselves, so long as they report to their Viceroy or Overlord. They often vary in power levels, with former mortal souls starting out naturally weaker than Hellborn Dealmakers, but build their way up by claiming and punishing souls (and making some deals with demons more powerful than themselves).

Summonables

These are demons who have a licence to respond to summons from humans. They tend to pay a fee to trademark their own sigil/ritual which can then be published in books by professionals. Summonables tend to have specialised in a type of magic to fill their own niche gaps in the markets. Many Succubi are unsurprisingly Summonables.

Haunters

These are what you likely think of when you hear the word ‘demon’. Hellborn creatures more beast-like than other Hellborns, they do not want to punish the truly evil or lure people into temptation out of spite or fun, they’re much simpler than that; they are evil. They’re bound by certain rules like all demons, but for the most part, these are the monsters mortals tell stories about. Creatures that simply want to kill and maim because they want to kill and maim, they tend not to even care where their murdered souls end up or even having control over them. Mischievous, cruel, and bloodthirsty, other demons prefer to keep their distance, and the Haunters are fine with this.

Tormentors

These are the demons who are tasked with torturing Sinners. Either Hell-born or hired Sinners who torment others to avoid it happening to themselves, and are often also Dealmakers or Succubi. They are given a select number of souls they are tasked with punishing to meet a quota. Honestly, it’s half torture but also half paperwork describing how/why they’ve punished a soul a certain way. These are smaller in number and often directly serve Overlords and Viceroys, and are therefore some of the most feared demons in Hell. In terms of political power however, they rank quite lowly, as they are pretty much thugs and secretaries.

The Viceroys

These are the Higher Ups who carry out the orders and wishes of the Deadly Sins. They allow the Overlords their territories within their own, truly ruling their District Sections. They keep the denizens of Hell in line, therefore hold the most power behind the Sins and Lucifer himself. The Viceroys are a mix of demons who want to build up their District populations and those who want humans to stop sinning and see those down in Hell as truly deserving of punishment. This can lead to disputes amongst themselves and their Overlords, although the most common point of contention is whose boss has more claim over a soul (as in, what was their main sin)

The Gula Five

The most powerful of the Viceroys. The five forms of Gluttony with the most control over their District, all of them working together better than the other Viceroys, although they do get along with a fair few of them as well as the Sins themselves.

#Smol's Demonverse #worldbuilding #may edit this later but for now it'll do so yall get the idea

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