Tumgik
#intralipids
orphancookie69 · 1 year
Text
My Infertility Journey: Part 4
Yeah, future me needs to go in the past and tell past me to not be crazy. Well, they have not arrived yet-part four starts. The sooner I get in the drivers seat the sooner I park my car in the winners circle I hope....Just hopping on late? Here is Part 1, Part 2, and Part 3. 
Tumblr media
August 2022: 
A week after the ERA comes a cycle. This is highly unusual as it does not normally come that soon. Second half of the month is the start of round 4. Initial ultrasound and bloodwork scheduled to see if the body is on the starting line. Now let’s talk about the definition of insanity, it is doing the same thing over and over again expecting different results. Based on the ERA, I am perfectly fine and we have been doing this with proper timing-so initially they said we are going to move forward with no changes. At consultation, they mentioned adding Intralipids-IV injected twice during the process. I am open to this idea, more than the anti-coagulants, because I think my body can only handle so many injections. I only have two more embryos at this point, and while I want to make sure they have the best odds of sucess-there are physical limitations of being...ya know...human? 
The results from the blood work came back, my hormones were too high. So they are having me wait and we will reassess on next cycle. I am happy that this news came from the doctor, I felt like it was better to wait and give the body a break. But for some reason, it felt like it would not have as much credence as it does coming from the doctor backed by “data”. I am looking forward to my break and plan on getting a family trip to Havasu in before my next cycle. PARTAY! No but otherwise this is a great time to hunker down and see if I can’t get some good training in for game day. Using muscle stims, heat, massage, and exercise to promote healing of the area. Maintaining diet and exercise to see if I can’t lose anymore weight before then. 
September 2022: 
Have I ever mentioned how much of this process is PLAYING THE WAITING GAME? But waiting has its own perks. So far just waiting for a cycle to come, estimated to come around the middle of the month according to P Tracker, and see if hormone levels are good enough to move forward. Also, I am (heavily) playing with the idea of implanting two instead of just one. My own doctor says the odds are better with just one, but I have heard a lot of other doctors/patients have success with 2. Part of me really likes the idea of implanting both and having this be the last round, for better or for worse. We will see what the doctor says. 
So my body decided to get stuck in “period limbo” this cycle. I get all the feels but none of the results. Doctor did a “wellness check” on me and decided to reset my cycle with a week’s worth of Birth Control. Then we are going to move on the next cycle. I picked up my prescription and then took them, one a day, for a week. My doctor puts me on Enskyce, and man I usually get all of the side effects: migraines, nausea, and lack of energy. 
October 2022: 
Body goes into cycle and then on Cycle Day 5, we went in for an appointment. Ultrasound and bloodwork looked good, we updated my thyroid panel as well. Now starts injections and the new element this time-intralipids. They are to be done at a third party facility, Oso Home Care in Irvine, in week 4 (before transfer) and after transfer. I am (attempting) to schedule an appointment with Oso Home Care after my next Ultrasound/Bloodwork appointment with Fertility Care in Brea. Ya know the one appointment(s) before implant. It is kind of crazy how much happens in a month. 
Drugs: EV (Estradiol Valerate), Dex (Dexamethasone), P4 (Progesterone), hCG, Valium, Doxy (Doxycycline Hyclate), Medrol (methylprednisolone),
Vitamins: Baby Aspirin, Prenatal vitamins (NAC, Prenatal, Omega 3, L Arginine, Coq10, Myo Inositol, D3)
Suggestions: Keto diet/Fasting, Exercise, Proper Injection Guidelines.
Price: $5,000+ (Fertility Care), $100+ (MDR Pharmacy), $550 (Oso Home Care), 
Here are some Injection Guidelines:
Before: Ice the area
During: Inject the right area, Massage it after
After: Walk it off a bit, Use a heating pad
In Between: Arnica, Massaging to promote healing
Check: Infection (red, raised/bumpy, burning, itchy)
Note: Injections are intramuscular, and depending on the injection, there are only so many spots you can inject. Just because there are other muscles, does not mean you can use them even if your areas are “out of commission”. You just gotta keep them in commission!
The phone tag that was had was fun by all? Honestly as much as this is not my first rodeo and this should not worry me, the intralipids worry me a bit. Really the scheduling process being the slowest thing ever doesn’t help anything either. Be careful when doing research too, it is not always as helpful as you would think to know what you are signing up for. Also, the slow time between the first and second appointment where there is only an injection every 3 days is lovely. So I barely got my appointment for the intralipid place, if I did not call, that might not have happened. Then went in for the next ultrasound, the last one before implant. Ultrasound was good and blood work was TBD. 
This starts the next phase of the process. From here we add 4 hCG shots, add 2 times a day of p4, and continue with EV every 3 days. Also, for the hCG...the first injection has to be in the back area, but the smaller ones can go in the stomach to give the back a bit of a break. Round one of the Intralipids happens. The dexamethasone comes off the schedule just before implant-a couple of meds get added for a couple days around implant. Implant happens, this time it will be a boy (currently between the names Roland and Kai). After implant it is suggested for up to 3 days of rest. Then we move into November (after playing the waiting game) to confirm the pregnancy. 
Oso Home Care...Intralipids: Its a cute little place in Irvine. Kind of disorganized and busy but it would seem a lot people go to a facility like this. I got there early. I spent 2.5 hours in the chair. Yeah, kind of a long time. The gals that work there are sweet, but I don’t like how they had to prick both my arms to get it to work. I felt strange after? I am not sure how I was supposed to feel. Based on when I left and where home is, it took an hour to get home. But I hope in the future that since I am already in the system that booking is easier, and I kind of have a better idea of what to expect. Dress comfortable, don’t bring a book. 
Ovation Fertility...Implant: I always forget COVID never stopped being a reality for hospital establishments. I always forget to bring a mask to these things. Arrive 15 minutes early in Newport Beach, take a Valium an hour before. Implant goes well-go home and rest. Also, if they let your partner in-film the implant. 
Implant day is a day of rest, and this time I am trying to take two more days of rest after. I am an awful patient and this is hard for me to do. Post transfer we ran low on p4 so we transitioned to 1/2 crinone and 1/2 p4 for the every 12 hour injections. There are enough drugs on hand to get through to the pregnancy test and once confirmed, we stick with this or go all crinone. I don’t remember my last boys’ implant well but this time around, my left uterus feels like a battle zone a bit. 
Trimester Breakdown:
Part 1: 10/7-1/8
Part 2: 1/9-4/12
Part 3: 4/13-7/15
November 2022: 
An appointment was set up to have a blood draw/pregnancy test on 11/7. What was the time like before? I felt most, if not all, the symptoms. Pray tell, what are the symptoms of the first trimester?
First Trimester Signs: Nausea, Metallic Taste, Foggy Brain, Cramps, Tiredness, Breast Tenderness,
For me, and according to old wives tales, boys are supposed to be worse. This round definitely felt different as I felt very sore for up to a week after implant. Google says this is ok but man, it was kind of odd. The first blood test of Week 4/5 happened and TBD. If this goes well, I go two more times-two days apart. In theory the HCG a pregnant body produces should double every day. The first time you are able to view anything on an ultrasound is week 6. The next, and final, intralipid appointment would also happen that week. 
The first blood test was good and positive, the next blood test the values should of doubled...and they did not. They increased but did not double. The office wants me to see the third test before jumping to any conclusions. The second blood draw was a 15% rise. The third blood draw was a 66% rise, so they kept us on the schedule and we scheduled the first ultrasound at 6 weeks 4 days. They also had me schedule my second, and last, intralipid appointment for that same day. Prior to going to going into the first ultrasound, there were 50/50 odds that this is a viable pregnancy. 
We went in for an ultrasound and there was a gestational sac, but nothing that could be seen in the sac. They did a blood draw, to confirm the hCG is rising as a pregnant body should be. I had an intralipid appointment but they wanted me to move it, and wait for the results. The beta was rising, so we stay in the game another week. Order more drugs from MDR Pharmacy and scheduled another ultrasound for the end of the week. The intralipid appointment was moved to the same day as the next ultrasound. 
Oso Home Care...Intralipids: This trip was shorter, already in the system and they have an idea of how quickly you take the liquids and what not. I believe this time was about 3 hours? 
Also, I am keeping track of my weight, as women who are overweight before need to be careful how much weight they put on. When I checked on it, I actually had lost weight. Between my keto diet, morning sickness, and other pregnancy symptoms. In the first trimester one can lose a bit, but should this trend keep up in the second trimester...we got problems. Went in for the next appointment and while it was still not where it was supposed to be, there was improvement in both Beta (blood draw) and ultrasound findings. By this time I am almost 8 weeks along and there should be some major organs created, like the heart. 
December 2022: 
The next ultrasound would be interesting as it was kind of the determined trip to “call it”. Why would I want to call it? Because since implant, it has been very “we don’t have good news but we have not bad news so keep injecting”. And the body can only take so much for something that they said was most likely to end in bad news? But the doctor makes a good point that while certain things should be in place by this appointment, babies can be “past their due date” so if they are slow to grow, as long as they grow, it is fine? As the train carrying the passenger, the “limbo” is annoying as hell. 
The Week 8 Ultrasound: Yeah, so that went about as good as that was going to. The doctor finally called it. It is sad, bumming, annoying, frustrating, relieving yet unwantedly so. They are three options to resolve this round: to let it happen naturally, use drugs to help “speed things along”, or get a D&C. For now, we are going to cancel medications and assess in another couple of days. Did a blood draw to see where the beta is, and establish a comparison point for declines in the future. 
For the next blood draw, I could of gone to my Fertility Care office-but with us at the sad end of the process-and them not being part of our insurance-we decided to finish the process in slightly more complicated insured way. They ordered the blood draw at Quest Diagnostics. I made an appointment and the results were sent to Fertility Care. I have seen some insurance that covers infertility, but for the most part that is a sad joke. Some jobs cover that too. If you need that as an option, it’s worth looking into. 
Pay attention to your body. I had sharp pains on my lower left abdomen area the day before the blood draw. Like, bad enough to make me basically pointless the rest of the night. The next day they continued, and I called it in. I am now on the alert for heavy bleeding and those pains, as the combination means bad news. But should be signs the body is starting the miscarriage process. To speed things up, they put me on Letrozole and Acetaminophen-COD. This will be my first time having a drug induced natural miscarriage.  
Four pills at night for 7 nights, bleeding can last up to a week. Blood was being drawn at Quest Diagnostics and the beta hcg was going down. I used pads for a week to “measure” how much I was bleeding, more than two pads in two hours was bad news. Blood draw to see where we were at, luckily enough for all involved-there was no hemorrhaging. The second week of miscarriage recovery-less blood, less medications, but no less feels? Research shows it could take up to 6 weeks for my body to get back to “normal”. There are some herbs and vitamins I can take to help, but mostly it was rest and food and relaxation. 
So, what happened? While there are no answers, there is a scientific name for this. Funny how that works out huh? Here is what I think happened: 
“ A blighted ovum, also called an anembryonic pregnancy, occurs when an early embryo never develops or stops developing, is resorbed and leaves an empty gestational sac. The reason this occurs is often unknown, but it may be due to chromosomal abnormalities in the fertilized egg.” (Source: https://www.mayoclinic.org/diseases-conditions/pregnancy-loss-miscarriage/expert-answers/blighted-ovum/faq-20057783)
Because this is an IVF process, and everything is tested and in some ways controlled, I doubt it is because of any chromosomal abnormalities. But it is crazy how many variations of miscarriages are out there. And really, even in the same person’s journey-no two are the same. Oh to know so much yet so little. 
Honestly, this is a very tough process. I am not sure what to think. Doctor thinks we should implant (IN ME) the last embryo, possibly changing nothing, and see if it works when I am mentally and emotionally ready. For now, the only thing for sure is its BREAK TIME. Is it too soon for a surrogate? I don’t understand how I can be such a medical mystery. It is a very strange feeling. 
2 notes · View notes
whumpy-daydreams · 5 months
Text
Drugs!
Masterlist
Everyone loves drugs, right? And boy are there some juicy ones in surgery. There are more, especially of emergency drugs, but these are some common ones
Anaesthetic drugs
Propofol - the main sleepy juice. It looks like milk, hence the name 'milk of amnesia' (also called jackson juice because it's what killed MJ)
Ketamine - horse tranquiliser. But also used for humans! Very fast acting, and gives good pain relief too (you only need a small amount)
Isoflurane, sevoflurane - anaesthetic gases (bye desflurane, you've polluted the atmosphere for too long)
Atracurium, rocuronium - reversible muscle relaxants, they take a few minutes to fully kick in
Neostigmine, sugammadex - muscle relaxant reversal, sugammadex (nicknamed sugar) is more powerful
Suxamethonium - nonreversible muscle relaxant. It wears off after 2-6 minutes unless you have a rare genetic condition. Also works really quickly (30 seconds)
Lidocaine, bupivacaine - local anaesthetic, injected into the area you want to numb, or used in a spinal anaesthetic
Benzodiazepines (midazolam, diazepam etc.) - sedatives, not enough to fully conk you out, but will make you a bit sleepy and more relaxed
Pain relief
Paracetamol (tylenol) - mild pain relief, can be given through IV for better results
Morphine - the simplest opioid, usually IV or given orally (apparently tastes a bit like liquorice?)
Fentanyl and alfentanyl - much stronger pain relief, used rarely except during induction of anaesthesia
Antibiotics
Not always given, used more in orthopaedics or where there's a risk of infection. The type given is usually up to the anaesthetist's preference unless there's an existing infection that's been cultured
Common ones: amoxicillin, vancomycin, gentamicin, clindamycin, flucloxacillin, doxycycline
Emergency drugs
Tranexamic acid - sometimes given at the start if there's a risk of bleeding. Helps to prevent blood loss
Atropine - increases heart rate
Glycopyrronium - increases heart rate, also reduces saliva production
Ephedrine - increases blood pressure
Metaraminol - increases blood pressure
Adrenaline - increases heart rate and blood pressure, used for cardiac arrests and anaphylaxis
Intralipid - treats local anaesthetic toxicity
Dantrolene - treats malignant hyperthermia (a life threatening condition where the body temperature raises really high)
Adenosine, amiodarone - treats arrhythmias
Digoxin - slows heart rate
21 notes · View notes
oreenolivia968 · 1 year
Text
Fertility Testing Clinic in Orange County, California
At Orange County-based Acacio Fertility Center, we perform different types of fertility testing to gain information about a woman’s or couple’s fertility and infertility. Get important information about fluid ultrasound or hydrosonography, which involves visualizing the endometrial or uterine cavity, intralipid therapy, a novel approach to the treatment of patients with immune based recurrent pregnancy loss (RPL) or failure of implantation, and the interpretation of reproductive immune blood tests. https://www.acaciofertility.com/health-library/fertility/fertility-testing                                                                      ��               
0 notes
rainbowinthemaking · 3 years
Text
Intralipid Therapy
Had intralipid infusion therapy this morning for the first time. This is something new we are trying to help maximize our success with our 2nd frozen embryo transfer.
What is it? Intralipid infusion therapy is used to improve clinical outcomes in patients with recurrent pregnancy loss (RPL) and/or recurrent implantation failure (RIF) with elevated natural killer (NK) cells. It is a mixture of high calorific natural fats containing soybean oil, egg yolk phospholipids, glycerine and water. Due to my RPL and last implantation failure our doctor believes that there is a small chance this will help.
The process was a little difficult due to my small veins. Usually I get IVs in the hand because of this. However, intralipids aren’t meant to go in your hand. After an hour we were able to get the IV in my wrist. I ended up bleeding a bit, needed quite the clean-up and then my IV started leaking. But nearly four hours later we were done! Hopefully next time we will stay in the 2-2.5 hour timeframe we were promised (this first time took FOUR hours!!!)
As far as side effects about an hour after finishing I got very hot and dizzy.  
We are hoping this will be the secret sauce to help our 2nd embaby stick. If all goes well I will be getting this treatment twice more. Once after a positive beta and again 5 weeks later.
2 notes · View notes
spankycomic · 3 years
Text
Hey guys. We’re in some serious debt for veterinary bills.
On 5/30/21 our dog Chunk started to act dizzy, then couldn’t stand. Within a few minutes he was having seizures and he was rushed to an emergency vet. Even with sedatives they didn’t go away and he continued to have spasms. The next day he threw up and was unresponsive and still spasming when we visited him. As a last ditch attempt we asked for him to be given intralipids, hoping he’d recover a bit since he’d thrown up what was in his stomach and if it was a poison it would bind to it. By the next day there was no improvement and he no longer had a gag reflex and we had to make the decision to put him to sleep.
He was an amazing dog and the whole family is heart broken that he’s gone. We decided to send him to be cremated and get his ashes back. Not only did we lose him but we’re now 3,800 dollars in debt to the vet, with nothing to show for it. If you could donate to help us pay off these bills it would mean the world to me and my boyfriend, as we’ve both already drained our savings to put towards it.
If you donate and would like some art please just shoot me a message. Any and all commissions will be going towards his bills. Please help us.
33 notes · View notes
kupakjoli · 4 years
Text
Emberkísérletek magamon vol. 2
Előzmény: https://kupakjoli.tumblr.com/post/620467219140411392/emberkísérletek-magamon-vol-1
4. Intralipid
Autoimmun beteg vagyok (Hashimoto thyreoiditis), de a 4 meddőségi klinika egyikén se javasoltak se immunológiai kivizsgálást, se különösebb kezelést ezzel összefüggésben. Pedig az autoimmun betegség ugyebár az immunrendszer túlműködése, így az emelkedett NK sejtarányt és/vagy a fokozott NK funkciót okoz, ami a magzat megtapadását gátolja, ismétlődő vetéléseket és beágyazódási zavarokat okozhat. Miután túl voltam egy biokémiai terhességen (azaz elindult valami, mérhető volt a HCG szint, de aztán leállt a folyamat), felkerestem egy jó endokrinológust, aki végül javasolta az Intralipid/Smoflipid infúziókúrát. Azt csak mellesleg jegyzem meg, hogy az NK lymphocyta funkció megállapítására szolgáló laborvizsgálatot az országban alig pár helyen végzik, és az ára 30-50 ezer Ft - természetesen a TB nem támogatja. 
Az Intralipid infúzió 20% szójaolajat, 1,2% tojássárgáját, glicerint és vizet tartalmaz. Sűrű, tápláló folyadék, amit olyan betegeknek adnak, akik valamilyen okból képtelenek szájon át táplálkozni és csövön át kell hozzájutniuk a napi kalóriamennyiséghez. Arra csak a nyolcvanas években jöttek rá, hogy hatására a szervezetben csökken a gyulladás, megerősödnek a sejtfalak és stabilizálódik az immunrendszer. Itthon csak néhány magánklinikán elérhető ez a kezelés. Egy infúzió ára 20-80 ezer Ft között mozog, mennyiségtől és klinikától függően, és egyetlen lombikkezelés alkalmával 3-5 db kezelés szükséges. Az infúziót járóbeteg kezelés keretében adják be, azaz besétálsz, megkapod, 1-2 óra alatt lecsorog, és mehetsz a dolgodra. Én jó pár kezelést kaptam, az 5 lombik és számtalan leállított stimuláció alatt és mondhatom, hogy egy branül beszúrásától, egy palack infúziótól már meg se rezzenek. Részben az Intralipid infúziónak köszönhetem a lányomat, ebben biztos vagyok.
5. Viagra
Fú, ezt nehéz lesz nem idegállapotban ismertetnem! A Viagra hatóanyagát, a szildenafil-citrátot a női meddőség kezelésében is eredményesen használják.  A szildenafil-citrát ugyanis elősegíti a méh vérellátásának növekedését, ezáltal nagyobb az esély a teherbeesésre az olyan nőknél, akiknek méhfala túlságosan vékony ahhoz, hogy egy megtermékenyített petesejtet befogadjon. A méhfalnak kb. 7 milliméter vastagságúnak kell lennie ahhoz, hogy be tudjon fogadni egy embriót, ellenkező esetben az nem tud beágyazódni. Ezt a kezelést - mondanom se kell - alig pár magyarországi magánklinikán javasolják, írják fel és követik. A ciklus elejétől a beültetés előtti napokig kell alkalmazni a szert, szájon át vagy hüvelyi úton. A bevétel utáni érzés valami leírhatatlan. Mintha nyakon öntenének egy vödör tűzforró vízzel, és egyúttal lehajtanék egy deci pálinkát. Elönt a forróság, szédülök, zúg a fejem, légszomjam van, képtelen vagyok koncentrálni. Vesztemre az első szemet a melóhelyemen vettem be, és olyan furán éreztem magam, hogy bujdosnom kellett, hogy kibekkeljem, míg csökken egy kicsit a hatás. Ezek után inkább lefekvés előtt vettem be, hogy átaludjam ezt a fura tripet. Nem is tudom, hogy tudnak teljesíteni a férfiak ilyen mellékhatások mellett. Mivel egy-két kezelés után kiderült, hogy a nyálkahártyám vastagsága nem fejlődött különösebben tőle, nagy örömmel abba is hagytam a kezelést.
6.  Endometrium scratching avagy méhkarcolás
Egy másik méhnyálkahártya-dúsító kezelés. A beültetés előtti ciklusban 2-3 alkalommal apró bemetszéseket ejtenek a méhnyálkahártyán. A bemetszések helyén új, friss szövet fejlődik, ami növelheti az embrió beágyazódásának esélyét, és ezáltal elősegíti a sikeres megtermékenyülést. Ismét leírom, hogy itthon alig pár klinikán végeznek ilyen beavatkozást, és kezelésenként több tízezer forintba kerül. Az eljárást járóbeteg-ellátás keretében történik, altatás és érzéstelenítés nélkül, és annyira fáj, hogy az - minden akaratomat, céltudatosságomat és őserőmet is összeszedve is - elviselhetetlen. Benyúlnak a testemen belülre egy szikével és vagdossák az önreprodukciós szervemet, naná, hogy tiltakozik a szervezetem. Ebből is végigcsináltam 4 kört, aztán, mivel eredményt nem értem el velük, úgy döntöttem, hogy nem kínzom magam tovább. Milyen jól tettem, enélkül is sikerült teherbeesnem.
7. Ratiograstim
A jolly joker, úgy hiszem, hogy ez hozta meg nálunk a sikert. A Ratiograstim injekció vagy infúzió hatóanyaga a filgrastim.  A Ratiograstimot (vagy bármilyen filgrastim készítményt) normál esetben kemó alatt, csontvelő átültetést követően, őssejt kezelésnél vagy HIV+ betegeknek adják, intravénásan.  A filgrastim vegyület a citokineknek nevezett fehérjecsoporthoz tartozik, és nagyon hasonlít a szervezetben termelődő egyik természetes fehérjéhez, amelynek neve granulocita-kolónia stimuláló faktor. A filgrastim arra serkenti a csontvelőt vagy azt a szövetet, ahol az új vérsejtek termelődnek, hogy több vérsejtet állítson elő, főként bizonyos típusú fehérvérsejteket. Meddőségi kezelésekben a méhnyálkahártya fejlődésének serkentésében van szerepe.
A lombik során intra-uterin használják a szert, azaz befecskendezik a méhbe, egyszerű járóbeteg kezelés keretében. Magyarországon nem elérhető ez a kezelés, én egy külföldi klinikán kaptam. Nem fájdalmas, de nem is kimondottan kellemes, viszont nálam roppant hatásosnak bizonyult. Sajnos ez se csodaszer, van, akinél nem működik. Én a beültetés ciklusa alatt 3 alkalommal kaptam, és míg korábban alig haladta meg a nyálkahártyám a 7 mm-t, sőt több stimulálást is le kellett állítani, mert a maximális ösztradiol mellett se fejlődött rendesen az endometrium, ettől a készítménytől felment 10 mm-re. 
Epilógus: ha gyereket akarsz, soha ne add fel. Nekem számtalanszor a szemembe mondták, hogy nincs tovább, nem lehet gyerekem, de nem tudtam elfogadni, hogy gyerek nélkül éljem le az életemet. Úgy éreztem, semmi értelme élnem gyerek nélkül. Nincs kiért hajtani, küzdeni, nem élhetem át a legnagyobb jót, hogy őrülten szeressek és szeressenek, és nem láthatok egy új kis életet kibontakozni, egy emberpalántát emberré fejlődni. Ezért addig kutakodtam, tájékozódtam, gugliztam, fórumoztam, és kísérleteztem magamon, míg végül sikerrel jártam. És elmondhatom, hogy a gyerek a legnagyobb királyság. Kifordítja a világomat a négy sarkából, de megéri minden nehézség, elköltött milliók és fájdalom, mert mi lehetne szebb és fontosabb, mint egy új élet.
54 notes · View notes
Photo
Tumblr media
Goldwell #nectaya #nectayacolor #nectayagoldwell #intralipid #sinamoniaco #amoniafree @ivangonzalezf @goldwellmexico @carlosherreraimagedesigners https://www.instagram.com/p/Bs9H45PlxM4/?utm_source=ig_tumblr_share&igshid=jatgr0z3mdov
0 notes
sevilstyle · 4 years
Photo
Tumblr media
La fórmula con pH equilibrado y la tecnología IntraLipid de #Colorance repara la fibra capilar y regenera los lípidos perdidos hasta un 70%. Ya sea para potenciar el brillo ✨ o para un cambio de color, en #peluqueriasevilstyle conseguirás exactamente los resultados de color que deseas y disfrutarás de un cabello más brillante, suave y sedoso. #salondebellezasevilstyle #ponteguapa #beuatyhair #goldwellespaña (en Aguadulce, Andalucia, Spain) https://www.instagram.com/p/CEzVEXror4O/?igshid=1jk2tkyjjpc5c
1 note · View note
Text
Tumblr media
Perfect outcome!!!! We have 5 embabies!!!!! Doing a day 6 transfer! Friday we will do the hcg wash and Intralipids. All I can do to make this stick in round one- we are trying!
4 notes · View notes
orphancookie69 · 2 years
Text
My Infertility Journey: Part 3
If you read part 1, and followed all the way to part 2, I know what you are thinking. What are you thinking? Based on two miscarriages, RIP Luella and Damien, this “possible” next round is a whole different ball game. Different risks, more knowledge, more pain, less hope. There are still options, and yes always hope, but we are into some different territory. 
Tumblr media
June 2022
This will pick up in part 3 where we left off in part 2. I can imagine your thoughts, did you take any time at all? My recovery time was shorter, as my body came back into normal mode way faster round 2 versus round 1. Mentally, emotionally, yeah I am still a wreck. To a certain degree I don’t think that is going away. Next step was to have a consultation about next steps. Next steps don’t necessarily mean let’s implant again. It might mean tests, but are there any tests I haven’t done? Will the tests be worth it? How invasive are the tests going to be?  Should we start considering the “S” word yet? 
We had a pow wow with our doctor. There is not a lot of tests I have not done, so we took a look at the file and figured out what we had done, and what we had not. They want me to go back on the fasting/keto diet and there we might have some disagreements, as I am not sure that it is working for me anymore but I am keeping an open mind. They want to do an ERA with the next cycle and do cancer testing, and possibly add anticoagulants / intralipids into the 3rd implant. Let’s break this down a little bit more. 
ERA/Cancer: This is a mock cycle in which instead of implanting after going on all the drugs “like normal” you take a skin scrape for Endometrial Receptivity Analysis. Based on my research, one should take a valium before the procedure, and while the actual pain of the procedure is short, it is supposed to suck. Day of the procedure one should have some spotting and have less than a day of recovery, and it will take 2-3 weeks to get the results back. The results will tell you if you need more or less or the same amount of preparation for implant. This is highly suggested for anyone with at least one loss to increase odds of sucess for the next implant. My doctor wants to take part of the skin scrape and have it tested for cancer. The only cancer I could find was endometrial cancer. If it is that we will get more into that, but I will tell you right now, it would make a lot of sense if I did have it. We are looking to see if this explains not only the losses but the unexplained bleeding that has happened since we started our fertility journey. The test for this is called EMB (Endometrial Biopsy). 
Anticoagulants/intralipids: So intralipids are extra nutrients that get delivered to your system by IV to make sure your body has everything it needs to make sure baby makes it. Diet should do so, but between pregnancy restrictions and fasting/keto diet, some doctors add this. I don’t know much more than that about it, once I know more I will update this section. Anticoagulants are blood thinners that are injected. I believe they are injected into ones stomach and it is supposed to help not have blood problems while on an IVF cycle. 
July 2022
In July, we are waiting for the body to have its first cycle since the miscarriage. Now there are two trains of thought, some people start the count down clock when the body comes to 0 beta results OR when the miscarriage happened. For me, the miscarriage happened in May/June 2022 and 0 beta happened in June 2022. At first the doctor said to call him by 7/15 if I did not have a cycle by then, but then he adjusted it to 8/1. 8/1 makes more sense, as it could take up to 3 months for the body to come back to normal with a cycle after a miscarriage. 3 months would be either: May June July OR June July August. So this month we play the waiting game. 
While we “wait in july” (god that feels like a wannabe twilight reference) let’s talk about how important it is to listen to your body. Coming out of miscarriage, I had “fever weekend” with rigors and really I was not ok even after I felt better. I was talking to doctors on the phone, but not going in to see one in person. Urine and blood testing were ordered and it showed my body was fighting some sort of infection, because I was feeling better they did not prescribe any medications. They arranged another urine/blood test to see what future results said. The second round of tests showed that there was still something not ok. They gave me antibiotics. They did confirm it was a UTI, but not much else. 
My theory: I had the miscarriage and with the changes I got a UTI, but it got lost in the shuffle. UTI’s that go unnoticed can turn into a kidney infection and the body could try to “fever it out” to fix itself. This combination is called Septic Shock. 
I took the antibiotics, and (as far as I know) I am all better now. The doctor doesn’t think the miscarriage has anything to do with it since the infection appeared in the second result. But it does not explain anything else that happened. Regardless of what happened, or happens, listen to your body and don’t be as stubborn as me in not going to get help. I am grateful that I am ok enough to pull myself through that, but luck will only get one so far. 
August 2022
This month my body would of had a natural cycle, or I will call my doctor and we will force a cycle with medication. My body was kind of coming in and out of cycle towards the end of month, so I called it and made an appointment to start the process again. Last week of July we had an appointment to have an ultrasound and blood work to see if we are good to start the ERA round, and if we are, we order more drugs from MDR. 
Went in for the appointment, and we are good to go. Schedule received, drugs ordered, and anxiety enters stage right. Let’s go over some of the basics in this cycle: 
Drugs: EV (Estradiol Valerate), Dex (Dexamethasone), P4 (Progesterone), hCG, Valium
Vitamins: Baby Aspirin, Prenatal vitamins (NAC, Prenatal, Omega 3, L Arginine, Coq10, Myo Inositol, D3)
Suggestions: Keto diet/Fasting, Exercise, Proper Injection Guidelines. 
Price: $2000 for the ERA, $500 for drugs from MDR, $325 for the EMB
Here are some Injection Guidelines: 
Before: Ice the area
During: Inject the right area, Massage it after
After: Walk it off a bit, Use a heating pad
In Between: Arnica, Massaging to promote healing
Check: Infection (red, raised/bumpy, burning, itchy)
Note: Injections are intramuscular, and depending on the injection, there are only so many spots you can inject. Just because there are other muscles, does not mean you can use them even if your areas are “out of commission”. You just gotta keep them in comission! 
Also, my Oscar insurance covered some of the drugs! Who would of guessed! We had one appointment today, we have another 10 days later to check the lining, and 6 days later is the ERA. I have heard the ERA is painful for not very long, but painful none the less. I will update this with those updates. Next appointment came, and I asked about Cancer testing prices and a Valium for the procedure. Next time we see the doctor, it is ERA time. 
ERA: Day of the test has arrived. I asked for a valium and received one, with instructions to take it an hour before the procedure. Also to not drive myself to the office. I will oblige. My procedure was at 11 am on a Thursday in August, and I took the valium at 10 am. Got to the office by 11 am. Procedure was prepped for and once started, very short. Dear god, just because that pain is only for a minute or less-does not mean that it is not the most excruciating and violating pain there really could be, with some complimentary cramps to go with it. I signed some paperwork and then left. Feeling wise after, it is sore and cramping and emotionally I am done. Plan for the rest of the day is to rest and recover from not only the procedure but from all the drugs in general. Day of was cramping and some spotting. Next day was better but not like myself yet. 
The “need for mental breakdown” came, as this is my second round IN THE SAME YEAR. It was my first panic attack, and it was a pretty scary thing. I tried to meditate, walk, sit, and finally exhaustion and ice cream lead to sleep. Update, I ran the numbers and based on the cycle that comes in August-its 21 days from day 1 to implant day, in theory the test results come just in time (if ontime) to know when to implant (early-normal-late). At this point, I have to decide a couple of things: do I go back so soon? I only have two more embryos left, am I ready to risk life or death for it? Holiday season is coming up, do I really want up to 12 weeks of injections starting pre halloween? 
ERA Results: If there is a “before” “normal” and “later” window for timing, I am the normal timing. WHICH I THOUGHT I WAS BASED ON THE LAST TWO IMPLANTS. But I guess I am glad I know for sure? 
EMB Results: No infections and no cancer. Yay?
Results came early, which I think is funny because I wanted to know the results before going into another cycle. Be careful what you wish for, the universe will grant it. I knew I was facing either “nothing is wrong with you” or “here is what is wrong/what you should of done before” when going into this. I am glad to be healthy but it leaves me answerless still. 
Highly Suggested: it is so important to have enough people you can count on, so that if your spouse who normally does the injections can’t, you can still keep on schedule. I almost missed one of my injections because I misread/missed it on the schedule and he had work. It is also a great idea to not be the only one reading the paperwork. Both should read, and ideally, the person giving the injections should understand and prep and clean them more than the partner being injected. It takes something off the injected’s shoulders and allows them to focus on getting through to the end line. Also, this is being added to this note as I was told by my spouse that I messed up the preparation of one of the injections, and we might have used the wrong needle one time. If you miss an injection, that is generally not good, but I am also on a lot of hormones right now and If I make a mistake, well its not that shocking. 
It is kind of crazy to me to think I could do three rounds of IVF in a year. But then the year before it took me a year to come out of my first miscarriage. Crazy stuff. Let’s say for shits and giggles, we implanted again in 2022, that means by christmas I am over the moon and sailing through my first trimester or sadder than puppy dog eyes. The bigger picture is an important thing to look at when going through this process. I can not believe I am considering a fourth part but stay tuned. 
0 notes
tumble-duh · 6 years
Text
IVF!
In case anyone wants to know what it really entails (or can entail, since our case is super convoluted).
Sperm - last cycle we bought sperm, $900 or so, and a pain to choose
This month, have to meet with Canada Dr to make sure he approves all this and will do bloodwork/ultrasounds and rewrite prescriptions so our insurance here pays for it). Also need him to approve doing the ERA biopsy.
Next month, biopsy hopefully. They time a mock cycle after taking estrogen and progesterone, then go in and rip a piece of uterine lining out to test it. Fun right?
Then month after is prep/priming cycle. After period, will add Lupron (injection) and estrogen (pills, possibly “insertable”) to take over hormone production and not allow my body to screw it up (which it clearly loves doing). Plus injecting human growth hormone to hopefully make the eggs stronger.
Once the next period comes, I’ll start injections of 2 kinds of hormones, gonal-f and menopur, plus add in an ovulation blocker, cetrotide, to grow hopefully 10-20 eggs. Once ready, add another injection, HCG trigger, to ready the eggs for removal.
Next up is the retrieval! Drive down to Syracuse again, get put to sleep and they repeatedly use a needle in my vagina to stab my ovaries and collect the eggs (having fun yet?). While in there, they will scratch the inside of my uterus, hopefully “roughing it up” and giving an embryo a better chance to attach.
Then we relax and go home to recover while hoping they have enough to freeze.
Then after the next period, I have to start MORE meds. Back to the estrogen and progesterone but this time adding in MORE meds. Blood thinner injection to the belly to reduce any chances of clots, prednisone to decrease any inflammation, low dose naltrexone to inhibit my immune system, intralipids in IV to battle natural killer cells, likely an HCG uterine wash (wide awake, they “flush” the uterus with hormone), will probably do acupuncture too. Then they hopefully put back in 1-3 embryos.
All this with multiple ultrasounds and blood tests to time it all, meaning TONS of people between my legs, time off work, travel, the wife taking days off. Ugh.
Total cost will probably be upwards of $10-12,000 again. Just for this cycle. 3+ months of planning, 2 countries/clinics/Drs, all to try ONCE! This is why it’s frustrating when random people ask “are you trying?” “Can’t you just ask a friend?” “How much could it REALLY cost?” “Just do IVF, it’ll be easy and done”
8 notes · View notes
rainbowinthemaking · 3 years
Text
New Game Plan
Tumblr media
We had our WTF appointment with our doctor Friday to come up with our new game plan. Since we have only one remaining embryo we have decided to be a little more aggressive with this transfer.
This cycle we will be doing an ERA to take a biopsy of my uterine lining to ensure we are transferring at the optimal time.
We will also be adding PIO (progesterone in oil) in addition to the estrogen and progesterone suppositories we used last transfer.
Dr. Elliott has suggested intralipid infusions during this next transfer cycle. We will be taking advantage of this as well. (Intralipid infusion is a therapy used to prevent recurrent miscarriages. It is a mixture of high calorific natural fats administered by IV 3 times during the transfer process.)
Fingers crossed all this extra work and medication will help embaby #2 stick.
If all goes well, we will be transferring again next month!
6 notes · View notes
coserty · 3 years
Photo
Tumblr media
La fórmula con pH equilibrado y la tecnología IntraLipid de #Colorance repara la fibra capilar y regenera los lípidos perdidos hasta un 70%. Ya sea para potenciar el brillo ✨ o para un cambio de color, conseguirás exactamente los resultados de color que deseas y disfrutarás de un cabello más brillante, suave y sedoso. . #cosertybeauty #goldwellcolorance #beautyroutine #cosertybeautyshop https://www.instagram.com/p/COEHfSvj3fe/?igshid=1i0cixfu2iety
0 notes
plantsasstic · 6 years
Text
Infertility treatments
Infertility is a global public health concern and affects approximately 10% - 15% of couples worldwide. This condition may stem from numerous anomalies in the body, ranging from infections and cysts in the ovaries and reproductive tract, to the disproportionate secretion of hormones by the glands. Infertility treatments are many, and are of various kinds. The best way to tackle it is to identify the exact cause of this condition and then alleviate it.
Available infertility treatments include:
. Treating APA's. APA's cause blood clots and prevent implantation. A low dose aspirin therapy works wonders when treating APA's in the blood. For graver cases, anticoagulants are used to thin out the blood and improve blood circulation in the uterus.
. Removing natural killer cells. Natural killer cells present in excess begin to attack the embryo. An intravenous treatment of gamma globulin, intralipid infusions and steroids are often used in this case.
. Treating Antinuclear Antibodies (AA's). Abundance of antinuclear antibodies in the body is treated with steroids, intake of herbs that increase circulation, intake of antioxidants, zinc supplements, alkaline generating food and reducing the levels of stress. Balancing the responses of the immune system is the key to treating AA's.
. Treating antisperm antibodies. To suppress the reactions in the body caused by antisperm antibodies interacting with the sperm, low doses of steroids are often made use of.
. Treating age related infertility. Since age is a possible threat to female fertility, infertility treatments involving care of the kidneys and the spleen will help a woman keep the age related problems of pregnancy at bay.
. Treating infections that hinder pregnancy. Antibiotic treatments to exterminate the harmful bacteria from the body are recommended by most doctors who conduct IVF's. Nutritious food and immune enhancing supplements are used to prevent harmful bacteria from growing in the body. When detected in one partner, antibiotic treatments for harmful bacteria must be carried out in both partners since they are likely to have infected each other during intercourse.
. Treating the high prolactin levels in the body. Normally, to treat the elevated levels of prolactin in the body, natural remedies are suggested. These natural remedies include the intake of vitamin B, zinc and magnesium supplements, exercising, staying away from alcohol, and lowering the levels of stress. The intake of rebalancing hormones like Chasteberry, etc. is also helpful. Qi moving herbs are also quite helpful in these cases.
. Treating leutal phase defects. In case of dealing with leutal phase defects, fertility drugs like Clomid, etc. are prescribed for boosting the levels of progesterone, which enable pregnancy. However, medicines such as these are bound to have side effects, and to avoid these said side effects, it is always beneficial to opt for natural methods of treatment. Traditional Chinese Medicine offers good help in these cases.
. Treating tubal blockages. Laparoscopy is performed to remove small areas of blockage, however if that fails, In Vitro Fertilization is an option.
. Treating sperm problems. Fertility drugs are available that enhance sperm production, and improve motility. Since sperm motility is one of the major factors affecting pregnancy, treatments in males are incomplete without looking into this.
Infertility treatments are possible with the whole new range of medicines that is available to the public these days, but it must also be kept in mind that these treatments can be painful, often come without harmful side effects and the results are far from guaranteed. On the other hand, following the holistic approach with a healthy diet, regular exercise, abstinence from alcohol, nicotine and other drugs, stress management, acupuncture etc. can almost guarantee positive and fast results.
learn how to get pregnant naturally with lisa olson’s pregnancy miracle guide at http://www.lisaolson.org.uk/
1 note · View note
Juniper Publishers- Open Access Journal of Toxicology
Innovative use of Intralipid in Critical Care Setting- Juniper Publishers
Tumblr media
Authored by Vikram Anumakonda
Abstract
A 42-year-old gentleman presented to hospital emergency department (ED), following a deliberate self-harm with an intentional overdose of 75mg Ramipril, 450mg Amlodipine and 10mg Penicillamine. His initial toxicology screen was negative for paracetamol, salicylate, alcohol or illicit drug. He had a single functioning left kidney, on background of hypertension, cysteinuria, chronic kidney disease (baseline creatinine 130150). On presentation to the resuscitation unit, he was normocardic (60/minute), hypotensive (88/41mmHg). His GCS was 15. He was oliguric. His preliminary blood tests revealed new onset acute kidney injury. His ECG showed normal sinus rhythm with a normal QTc. Blood gas analysis revealed compensated metabolic acidosis; pH and lactate were within normal limits, but his base excess was -3.7. Despite intensive fluid resuscitation and administration of glucagon and calcium chloride to antagonise calcium channel blocker in the resuscitation department, he remained persistently hypotensive and oliguric. He only passed 30mls ofurine during his 8 hours of being in hospital, and his base excess was static around -3.0. He was admitted to the intensive care unit for vasopressor support, with an intent of improve blood perfusion to his only kidney, to mitigate further insult to his remaining renal function. He was started on noradrenaline with a target invasive mean arterial blood pressure (MAP) of 65-70mmHg. However, his MAP did not respond to maximum dose of noradrenaline and crystalloids. In view of his deliberate over dose, the National In patient Poisons Service (NPIS) advice was sought. They advised to start patient on insulin infusion with back ground 10% glucose infusion and supportive therapy.
For more Open Access Journals in Juniper Publishers please click on: https://juniperpublishers.com For more articles in Open Access Journal of Toxicology please click on: https://juniperpublishers.com/oajt/ To know more about Peer Review Journal of Toxicology To read more… Full text please click on: https://juniperpublishers.com/oajt/OAJT.MS.ID.555567.php
0 notes
graefinz · 7 years
Text
Verfi**te Schei*e!
Wieder hat das alles nichts gebracht! Die ganzen teuren Medikamente, die Akupunktur, die Kräuter, das positive denken, Ruhe walten lassen, das andere Schema, die Infusion...nichts davon hat geholfen. Mein Körper scheint nicht durch künstliche Befruchtung schwanger werden zu können. Am 19.01 starteten wir in den Kryo-Zyklus, ab 21.01 mit 2x2 Progynova und Mono Embolex, ab 31.01 abends mit Utrogest 2x3 und ab 02.02 kam dann noch Prolutex dazu. Am 30.01 war meine Schleimhaut bei 10,5mm - Dreischichtig. Perfekt wie die Ärztin sagte. Intralipid gab es an diesem Tag auch noch. Am 06.02 sind dann zwei tolle Blastozyste bei mir eingezogen...eine "einfache" und eine expandierte. Alles in allem super Voraussetzungen...besser geht es bald nicht und trotzdem wieder mal negativ. Ich könnte kotzen!!!
2 notes · View notes