#genetic material health

[onlineshoppinginsouthafrica]

Genetically Modified Organisms (GMOs) are organisms whose genetic material has been altered using biotechnology to create specific desired traits. GMOs have been widely used in agriculture to improve crop yield, enhance resistance to pests and diseases, and increase the nutritional content of food.

#Genetically Modified Organisms #GMOs #genetic material health #adverse effects #adverse effects of GMOs

[bethanythebogwitch]

Gather round, children, and let me tell you the tale of the sturddlefish. In the year 2019 in the mythical land of Hungary’s Research Institute for Fisheries and Aquaculture, some scientists were trying to save some endangered fish. The Russian sturgeon and American paddlefish are distantly related species that are both endangered. The scientists were trying to induce gynogenesis in the sturgeon. 

This is a type of parthenogenesis (single parent reproduction) where sperm triggers the embryo growth, but doesn’t contribute genetic material. In any type of parthenogenesis, the offspring is basically a clone of the mother. 

The scientists needed to have sperm interact with the eggs without inseminating them. So they used paddlefish sperm. Since paddlefish diverged from sturgeons 184 million years ago, the scientists figured that there was no chance of insemination. 

Much to their surprise, the paddlefish sperm did fertilize the sturgeon eggs, creating the hybrid sturddlefish. This was not expected at all due to his distantly related the parent species are. There were two sturddlefish populations from the same breeding. One that was 50% sturgeon and paddlefish and one that had twice as much sturgeon due to chromosome doubling. Only about 2/3 of the sturddlefish survived longer than a month and only about 100 survived past a year. Hybrids often have health problems that limit their lifespans. Given how long-lived the parent species are, a healthy sturddlefish could live for a long time. 

The sturddlefish will live out their lives in the research institute and the scientists have no plans of making more. I don’t know if any of them are still alive. For a brief time, a new lifeform will have come into existence by sheer accident and will soon be extinct. May they Rest In Peace 

Image from a to d: Russian sturgeon, mostly sturgeon hybrid, even hybrid, American paddlefish

#fishblr #fish #biology #zoology #science

[mariacallous]

Updated vaccines against Covid-19 are coming, just as hospitalizations and deaths due to the virus are steadily ticking up again.

Today, the US Food and Drug Administration authorized new mRNA booster shots from Moderna and Pfizer, and a panel of outside experts that advises the Centers for Disease Control and Prevention voted to recommend the shots to everyone in the United States ages 6 months and older. Once Centers for Disease Control and Prevention director Mandy Cohen signs off on the recommendations and the vaccines are shipped, people can start getting the boosters.

The recommendation is projected to prevent about 400,000 hospitalizations and 40,000 deaths over the next two years, according to data presented at the meeting by CDC epidemiologist Megan Wallace.

This year’s mRNA vaccines are different from the 2022 booster in a key way. Last year’s shot was a bivalent vaccine, meaning it covered two variants: the original one that emerged in China in 2019, plus the Omicron subvariant BA.5, which was circulating during much of 2022. This fall’s booster drops the original variant, which is no longer circulating and is unlikely to return. It targets just the Omicron subvariant XBB.1.5, which was dominant throughout much of 2023.

Pfizer and Moderna’s vaccines work by introducing a tiny piece of genetic material called messenger RNA, or mRNA, that carries instructions for making SARS-CoV-2’s characteristic spike protein. Once it is injected, cells in the body use those instructions to temporarily make the spike protein. The immune system recognizes the protein as foreign and generates antibodies against it. Those antibodies stick around so that if they encounter that foreign invader again, they will mount a response against it.

Since the start of the Covid-19 pandemic, the virus has acquired new mutations in its spike protein and elsewhere. These mutations result in new variants and subvariants that diverge from the original virus. When enough mutations accumulate, these new versions can more easily evade the antibodies created by previous vaccine doses or infections.

The constantly evolving nature of the virus is the reason health regulators decided last year to update the original mRNA vaccines, which were designed against the version of the virus that first appeared in 2019. This year, once again, the virus has changed enough to warrant an updated booster.

In June, an advisory committee to the FDA recommended that this fall’s booster be a monovalent vaccine—targeting only the then-dominant XBB.1.5 subvariant.

At that meeting, committee members reviewed evidence suggesting that the inclusion of the original variant may hamper the booster’s effectiveness against newer offshoots. “The previous bivalent vaccine contained the ancestral spike and thus skewed immune responses to the old spike,” says David Ho, a professor of microbiology at Columbia University whose research, which is not yet peer-reviewed, was among the evidence the FDA panel reviewed. “This is what we call immunological imprinting, and it results in lack of immune responses to the new spike.” He thinks taking out the old variant should optimize the immune response.

But over the past few months, even newer Omicron offshoots have arrived. Currently, EG.5.1, or Eris, is the dominant one in the United States, United Kingdom, and China. Meanwhile, a variant called BA.2.86, or Pirola, has been detected in several countries. Pirola has raised alarm bells because it has more than 30 new mutations compared to XBB.1.5.

Even though the new boosters were formulated against XBB.1.5, they’re still expected to provide protection against these new variants. “The reason is, while antibodies are important in protection against mild disease, the critical part of the immune response that’s important for protecting against severe disease is T cells,” says Paul Offit, a professor of vaccinology at the University of Pennsylvania and member of the FDA’s vaccine advisory committee.

These cells are a different part of the immune response. Unlike antibodies, which neutralize a pathogen by preventing it from infecting cells, T cells work by eliminating the cells that have already been invaded and boosting creation of more antibodies. Both the Moderna and Pfizer-BioNTech Covid vaccines produce long-lasting T cells in addition to antibodies.

It’s why, Offit says, when the Omicron wave hit in late 2021 and peaked in January 2022, the US didn’t see a dramatic increase in hospitalizations and deaths even as cases rose significantly: People’s T cells kicked into gear, even when their antibodies didn’t recognize the Omicron variant.

“In some ways,” says Offit, when it comes to vaccine booster development, “it almost doesn’t matter what we pick to target” because the coronavirus has yet to evolve away from T cell recognition. “Everything works.”

Scientists think T cells are able to protect against severe Covid because they’re recognizing parts of the virus that have remained unchanged throughout the pandemic. “I suspect that as we continue to vaccinate, there are some conserved regions [of the virus],” says Jacqueline Miller, Moderna’s head of infectious diseases. “So even with the accumulation of mutations, we’re still building on previous immunity.”

People who have hybrid immunity—that is, have had a Covid infection and have also been vaccinated—seem to have the best immune responses to new variants, she says, which suggests that previous exposure shapes and improves immune responses to new variants. Preliminary studies show that antibodies generated by previous infections and vaccinations should be capable of neutralizing Pirola.

Earlier this month, Moderna issued a press release saying that clinical trial data showed that its updated booster generated a strong immune response against Pirola, as well as the more prevalent Eris variant.

In a statement to WIRED, Pfizer spokesperson Jerica Pitts said the company continues to closely monitor emerging variants and conduct tests of its updated monovalent booster against them. Data presented at Tuesday’s CDC meeting showed that Pfizer-BioNTech’s updated booster elicited a strong neutralizing antibody response against both Eris and Pirola.

The FDA expects that Covid-19 vaccines will continue to be updated on an annual basis, unless a completely new variant emerges that requires a different approach. “We will always be a little behind the virus,” says Ho. “In this instance, we won’t suffer too much, but that might not be the case going forward. Surveillance is imperative.”

[swampgallows]

Now we know how COVID attacks your heart

Even patients with mild COVID symptoms could face a higher risk of developing heart disease and stroke

By Sanjay Mishra Nov 07, 2023 04:08 PM 5 min. read

Scientists have noticed that COVID-19 can trigger serious cardiovascular problems, especially among older people who have a buildup of fatty material in their blood vessels. But now a new study has revealed why and shown that SARS-CoV-2, the virus that causes COVID-19, directly infects the arteries of the heart.

The study also found that the virus can survive and grow inside the cells that form plaque—the buildup of fat-filled cells that narrow and stiffen the arteries leading to atherosclerosis. If the plaque breaks, it can block blood flow and cause a heart attack or a stroke. The SARS-CoV-2 infection makes the situation worse by inflaming the plaque and increasing the chance that it breaks free.

This can explain long-term cardiovascular effects seen in some, if not all, COVID-19 patients.

SARS-CoV-2 virus has already been found to infect many organs outside the respiratory system. But until now it hadn't been shown to attack the arteries.

"No one was really looking if there was a direct effect of the virus on the arterial wall," says Chiara Giannarelli, a cardiologist at NYU Langone Health, in New York, who led the study. Giannarelli noted that her team detected viral RNA—the genetic material in the virus—in the coronary arteries. “You would not expect to see [this] several months after recovering from COVID.”

Mounting evidence now shows that SARS-CoV-2 is not only a respiratory virus, but it can also affect the heart and many other organ systems, says Ziyad Al-Aly, a clinical epidemiologist at Washington University in St. Louis. Al-Aly's research has shown that the risk of developing heart and cardiovascular diseases, including heart failure, stroke, irregular heart rhythms, cardiac arrest, and blood clots increases two to five times within a year of COVID-19, even when the person wasn't hospitalized.

"This important study links, for the first time, directly the SARS-CoV-2 virus with atherosclerotic plaque inflammation," says Charalambos Antoniades, chair of cardiovascular medicine at the University of Oxford, United Kingdom.

Virus triggers the inflammation in plaque

A recent study of more than 800,000 people led by Fabio Angeli, a cardiologist at University of Insubria in Varese, Italy, has shown that COVID-19 patients develop high blood pressure twice as often as others. More worrying is that the risk of cardiac diseases can also rise for patients who suffered only mild COVID symptoms.

"I saw a patient who now has a defibrillator, and she didn't even have a severe [COVID] illness," says Bernard Gersh, a cardiologist at Mayo Clinic, Rochester, Minnesota.

Wondering whether the cardiovascular damage during COVID was due to the virus directly attacking the blood vessels, the NYU team analyzed autopsied tissue from the coronary arteries and plaque of older people who had died from COVID-19. They found the virus was present in the arteries regardless of whether the fatty plaques were big or small.

"The original finding in this study is that the virus was convincingly found in the plaque in the coronary artery," says Juan Carlos Kaski, a cardiovascular specialist at St George's, University of London, who was not involved in the study.

The NYU team found that in the arteries, the virus predominantly colonized the white blood cells called macrophages. Macrophages are immune cells that are mobilized to fight off an infection, but these same cells also absorb excess fats—including cholesterol from blood. When microphages load too much fat, they change into foam cells, which can increase plaque formation.

To confirm that the virus was indeed infecting and growing in the cells of the blood vessels, scientists obtained arterial and plaque cells—including macrophages and foam cells—from healthy volunteers. Then they grew these cells in the lab in petri dishes and infected them with SARS-CoV-2.

Giannarelli found that although virus infected macrophages at a higher rate than other arterial cells, it did not replicate in them to form new infectious particles. But when the macrophages had become loaded with cholesterol and transformed into foam cells, the virus could grow, replicate, and survive longer.

"We found that the virus tended to persist longer in foam cells," says Giannarelli. That suggests that foam cells might act as a reservoir of SARS-CoV-2. Since more fatty buildup would mean a greater number of foam cells, plaque can increase the persistence of the virus or the severity of COVID-19.

Scientists found that when macrophages and foam cells were infected with SARS-CoV-2 they released a surge of small proteins known as cytokines, which signal the immune system to mount a response against a bacterial or viral infection. In arteries, however, cytokines boost inflammation and formation of even more plaque.

"We saw that there was a degree of inflammation [caused] by the virus that could aggravate atherosclerosis and cardiovascular events," says Giannarelli.

These findings also confirm previous reports that measuring inflammation in the blood vessel wall can diagnose the extent of long-term cardiovascular complications after COVID-19, says Antoniades.

"What this study has found is that plaque rupture can be accelerated and magnified by the presence of the virus," says Kaski.

Understanding heart diseases after COVID

While this new research clearly shows that SARS-CoV-2 can infect, grow, and persist in the macrophages of plaques and arterial cells, more studies are needed to fully understand the many ways COVID-19 can alter cardiac health.

"The NYU study identifies one potential mechanism, especially the viral reservoir, to explain the possible effects" says Gersh. "But It's not going to be the only mechanism."

This study only analyzed 27 samples from eight elderly deceased patients, all of whom already had coronary artery disease and were infected with the original strains of virus. So, the results of this study do not necessarily apply to younger people without coronary artery disease; or to new variants of the virus, which cause somewhat milder disease, says Angeli.

"We do not know if this will happen in people who have been vaccinated," says Kaski. "There are lots of unknowns."

It is also not clear whether and to what extent the high inflammatory reaction observed in the arteries of patients within six months after the infection, as shown in the new study, will last long-enough to trigger new plaque formation. "New studies are needed to show the time-course of the resolution of vascular inflammation after the infection," says Antoniades.

COVID patients should watch for any new incidence of shortness of breath with exertion, chest discomfort, usually with exertion, palpitations, loss of consciousness; and talk to their physician about possible heart disease.

#covid #covid 19 #long covid #national geographic #sars cov 2

[we-the-human]

If you asked me if I had a pet and I said “yes, I have a stallion”, you know exactly what I am talking about.

I have a male horse. That is his definition. Just a word that describes him based on his sex and his species.

That doesn’t mean that’s ALL I see him as. He could be my best friend, my confidant, and we provide each other affection and happiness. I would groom and clean him, feed him, take him out riding everyday, bond with him. I would treat him when he’s sick - pay thousands of dollars to treat an injury or infection. He’s my best buddy and I love him. He is a Stallion, but his definition is not what he is to me.

Other people in the world purchase stallions for one reason and one reason only. To make money and breed. Someone could purchase a stallion, put it through gruelling paces to train it to its full potential, even at the cost of his health. He would be groomed and fed only because it increases the worth of his performance and thus his sperm. The only things he gets is to further his usefulness as either a horse whose actions directly make money, including his genetic material. He is not given affection or love outside of this. If he became injured, he would be put down. This is someone who only treats a stallion as his definition - a male horse capable of producing sperm that can be exchanged for money.

A man is a human male. He is in possession of a Y chromosome(s). His genetic instructions will attempt to create sperm. He may or may not succeed. He will NEVER produce ova.

A woman is a human female. She is only in possession of X chromosomes. Her genetic instructions will attempt to create ova. She may or may not succeed. She will NEVER produce sperm.

I do not see men and women as their definitions. We are people with feelings and dreams and lives.

Some people DO see others as simply a means of reproduction - mostly men in regards to women across the world. Our sex is what we are oppressed by. It is not all we are, it is just that some people want to own us simply for being women - like the stallion. CONTINUING to define man and woman on the basis of species and sex is important because sex is the basis on which women are oppressed and if we can’t define our oppression and make policies off that then we will devolve.

We have a definition for men. We have a definition for women. This is all that is, a definition.

No one can be both. No one can switch between the two.

#gender critical #gender studies #gender #trans #feminism #women’s rights

[scientia-rex]

Do you have thoughts about dealing with your ADHD without medication? I'm in Europe where the laws are different and its haaaaard to access meds. (Immigration is very bad for consistent health care)

Yeah, I mean, caffeine. Caffeine in the mornings and propranolol if I overdo it or have too much caffeine after 1pm. Caffeine has a variable half-life depending on your genetics, so for some people they can have caffeine within about 4-5 hours of trying to sleep and for me if I have it within 9 hours of when I want to sleep I'm a little fucked. (5-9 hours is a relatively typical range for half-life.) Caffeine has active metabolites, which means that as your body processes it to break it down it creates different molecules which are still stimulants, so it's not as simple as "caffeine in, break it down, inert molecule out." You also need to be aware that your brain WILL develop tolerance, so taking drug holidays where you have a chaotic, disorganized day will help when you go back to work.

Another alternative is Strattera, generic name atomoxetine, which gets marketed as a "non-stimulant" ADHD medication. In my opinion it does still have stimulant qualities and the classification has more to do with legal status than medical reality. However, it does have a tendency to cause nausea, so I usually start people low (10mg) and ramp up to 80-100mg, which is target range for efficacy for most people. It doesn't seem as effective as the stimulants but it also doesn't have the legal implications of the stimulants.

Wellbutrin, generic name bupropion, is an antidepressant, but it's not the same as SSRIs or SNRIs--it has its own combination of effects on neurotransmitters that makes it a cousin rather than a sibling drug. It can be used (off-label) for ADHD.

In terms of other things I do to help myself cope, setting and maintaining a sleep schedule is critical. I definitely always feel like I'm being asked to wake up at the equivalent of 3am for other people. This means I need to make sure I go to bed and get up at consistent times, including days off. Bed needs to be for sleeping and intimacy and not for being activated--not for reading, not for hanging out. "Sleep hygiene" is about training your brain that when you go to bed, you go to sleep. The bedroom needs to be quiet, cool, and dark. You can Google sleep hygiene for more information on that.

Learning how to learn was critical for surviving med school. I didn't struggle that much with the material even in grad school, though I was more miserable overall in grad school. The sheer volume meant I couldn't just read everything once and figure enough would stick; I had to read, listen, watch, and eventually I figured out that I really needed to draw pictures and make myself flash cards if I wanted to actually force my brain to retain anything. Making sure I was physically comfortable, including that I was fed, hydrated, and didn't have to pee, was also part of the process. Getting there involved lots of tears and failing multiple tests.

Cleaning can't be an all or nothing proposition or nothing ever gets cleaned. When I start cleaning, I just grab whatever I'm walking by that catches my attention. Fuck doing whole tasks at a time consistently. Move those three bowls to the sink, in the kitchen realize I need to take out the recycling, take out the recycling and realize on the way back in that I have a load of laundry to start, start the laundry and realize I need to pee, while I'm in the bathroom realize I need to clean the counter, clean the counter and realize I need to take out the bathroom trash, take out the bathroom trash and realize I still didn't pee, continue until I'm too tired and then sit down and have a snack and a nap. My house is still a black hole but it's infinitely better than my apartments when I was younger.

Accepting that you can't do things the neurotypical way is a big part of it. Giving up on how things "should" be and recognizing what you can do and how you can do it is critical. I will never stop crashing into things so I've bought rounded furniture that hurts less when I crash into it. I'm slowly designing a life and a home where I'm playing to my strengths, and although it's a work in process, I'm slowly becoming happier.

#the attending dr. kristophine

[a-d-nox]

what's a dna (asteroid 55555) persona? what can a dna persona chart show you?

hypothetically, your dna chart can tell you more about the genetic predisposition of your health, what genetic diseases and mutations you are at risk for, your ancestry, and your genetic traits.

mini disclaimer: genetic/ethnicity/ancestry can be a delicate subject for a lot of people - this is is topical post about what the planets and houses could mean. i am not a doctor or geneticist - this chart can not be used to diagnose health issues/problems or anything else with 100% accuracy.

sun

your genetic identity, your projected vitality, genetic predispositions you should pay attention to, genetic prominence, genetic connects to royal/famous/infamous individuals, and/or how your genetics are different from your ancestors / what makes you an individual (not a clone - or perhaps different from a twin)

moon

what you inherited from your mother, your family's heritage, how your ancestors have adapt/evolved to make you who you are today, neanderthal ancestry ratios, hereditary menstrual issues, genetic fertility factors, and/or the brca / pcos / uterine fibroids gene

mercury

genetic mental health conditions, neurological conditions/diseases, taste/smell/hearing, how you can change your genetic "fate," what genetics can be forgot, aptitude to speak the languages of your ancestors, and/or how your daily routine affects your genetics (nature versus nurture)

venus

genetic attraction / who you attract to create viable offspring that is meant to survive, your genetic beauty, your ability to preform self love (aka your ability to cope with hereditary depression and anxiety), genetic hair type, genetic femininity (xx, x0, xxx, etc), genetics you share with a majority of your family, values and festivities with have due to heritage, genetics diabetes, genetic cheerfulness versus depression, and/or pcos gene

mar

genetic confidence in public speaking, competitiveness that makes your genes superior to past generations, genetic athleticism / muscle composition, genetic masculinity (xy, xxy, etc), genetic dominance, and/or prone to violence (neanderthal influence)

jupiter

where you are lucky in the genetic lottery, where you have an abundance of genetic information, where are successful in breaking genetic trends, your opportunity to beat the genetic odds, your knowledge of your genetic makeup, genetic blessings, where you can afford to be optimistic about your health, and/or genetic predisposition to macular degeneration

saturn

what you should work hard to be your genetic makeup, genetic health challenges, what you inherited from your father, genetics fears/anxieties, how long you can live if you are healthy, your genetic limitations, ancestry, genetic deficiencies, and/or the effort you make to beat your genetics

uranus

genetics of social anxiety, sudden changes historical genetics - where you are the first in your family diagnosed with a genetic mutation/disorder, what makes you genetically unique, and/or shocking/unexpected ancestry/origin

neptune

genetic alcoholism/escapism, hidden genetic knowledge or ancestry, delusions surrounding your heritage, disappearance of heritage, and/or the fascination you have with your ancestry and genetic

pluto

genetic transformation, the power in your genes, genetic sex, destructive genes, you genetic projected death, regenerative genes, your obsession with your genetics and heritage, and/or your genetic evolution

1h

genetic identity/self, outward physical traits / appearance, physical body, physical genetic build, genetic individuality, and/or passion for genetics

2h

genetic wealth, effort you put in to beat your genetics, genetic material, values surrounding your heritage, genetic stability, giving/receiving your heritage, and resources surrounding your genetics

3h

how your genetics are communicated, genetic mental health issues and disabilities, your opinions about your heritage, how you can consciously fight your genetics, genetic relationship with your siblings, interest in your heritage and genetics, and/or information you have on your ancestry and genetics

4h

genetic/familial origins and roots, your parents genetics, how you were treated in childhood based on your genetics, heredity traits, traditions you upload because of your heritage, and/or genetic femininity

5h

your children's genetics, creative methods of celebrating your heritage, who you are attracted to based on genetics/ethnicity, vacations you take to reconnect with your heritage/ethnicity, hobbies/festivities/traditions that are related to your ethnicity, and/or genetic fertility (pcos, fibroids, etc)

6h

how your daily routine is affecting your genetics or rather triggering your genetics, your genetic health, how fitness/hygiene/medication/diet can benefit for life expectancy because of genetic factors, the self improvement you do to fight genetic pre-destiny, how consistency aids/harms your health, how you help others to better understand their origin, and/or genetic analytics

7h

your significant others' ethnicity/heritage, genetic attraction, genetic attractiveness, contracts with genetic storage banks (for instance mine is in a 23&me storage data bank), how others treat you based on your genetics, and/or genetics share with those in your family

8h

dna mutations, projected longevity based on your genetic makeup, changes you should make to live longer, how much time invest into getting to know more about your genetics and heritage, what you inherited from your ancestors genetically, genetic reproductive rates, assets of your ethnicity, secrets about your ethnicity, the spiritual transformation that occurs when you learn more about your heritage/roots, and/or trauma related to race/ethnicity/heritage

9h

beliefs/religion/ideologies associated with your roots, what can learn about your heritage/ethnicity, languages associated with your roots, where your ancestors immigrated or where they emigrated from, genetic ethics, and/or what you can learn about your ancestors

10h

your genetic legacy/offspring, what the world believes your origins are, how you can beat genetics, long-term health goals you may have, what you inherit from your father, and/or genetic experts in your life

11h

what you gain from having knowledge of your ancestors, genetics you share with a half sibling, what makes you genetically unique, how technology can help you learn more about your genetic background, social awareness you have others ethnicities/culture/heritages, and/or how your genes manifest

12h

how you can heal using your genetic information, the hidden features of your genetic code, your projected age, how well you sleep based on your genetics, mental health issues you have a predisposition to, genetic fears you have in place so that you can survive, what you don't know about your genetics, and/or how you should restrict yourself to promote longevity/vitality

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#astrology #astro community #astro placements #astro chart #asteroid astrology #asteroid #natal chart #persona chart #astrology tumblr #astronotes #astrology readings #astro notes #natal astrology #astro observations #astroblr #asteroid55555 #dna #asteroid dna

[reasonsforhope]

This is maybe an odd thing to put on a good news/reasons for hope blog, but I've also had people tell me that they find this info really, genuinely comforting, so I'm putting it up. Also, further understanding could do a ton to advance medicine, esp. re: allergies, autoimmune diseases, and depression. You can read more about this at the link.

"More than half of your body is not human, say scientists.

Human cells make up only 43% of the body's total cell count. The rest are microscopic [co-contributors].

Understanding this hidden half of ourselves - our microbiome - is rapidly transforming understanding of diseases from allergy to Parkinson's.

The field is even asking questions of what it means to be "human" and is leading to new innovative treatments as a result.

"They are essential to your health," says Prof Ruth Ley, the director of the department of microbiome science at the Max Planck Institute, "your body isn't just you."

No matter how well you wash, nearly every nook and cranny of your body is covered in microscopic creatures.

This includes bacteria, viruses, fungi and archaea (organisms originally misclassified as bacteria). The greatest concentration of this microscopic life is in the dark murky depths of our oxygen-deprived bowels.

Prof Rob Knight, from University of California San Diego, told the BBC: "You're more microbe than you are human."

Originally it was thought our cells were outnumbered 10 to one.

"That's been refined much closer to one-to-one, so the current estimate is you're about 43% human if you're counting up all the cells," he says.

But genetically we're even more outgunned.

The human genome - the full set of genetic instructions for a human being - is made up of 20,000 instructions called genes.

But add all the genes in our microbiome together and the figure comes out between two and 20 million microbial genes.

Prof Sarkis Mazmanian, a microbiologist from Caltech, argues: "We don't have just one genome, the genes of our microbiome present essentially a second genome which augment the activity of our own.

"What makes us human is, in my opinion, the combination of our own DNA, plus the DNA of our gut microbes."

It would be naive to think we carry around so much microbial material without it interacting or having any effect on our bodies at all.

Science is rapidly uncovering the role the microbiome plays in digestion, regulating the immune system, protecting against disease and manufacturing vital vitamins.

Prof Knight said: "We're finding ways that these tiny creatures totally transform our health in ways we never imagined until recently."

It is a new way of thinking about the microbial world. To date, our relationship with microbes has largely been one of warfare.

-via BBC News, April 10, 2018

#cw germaphobia #germaphobia #bacteria #viruses #fungi #archaea #dna #genome #genetics #biology #human biology #public health #biodiversity #technically it is biodiversity! #increasingly we learn that your own body needs to be biodiverse to even form properly #some of the studies we have on this are literally kinda mindblowing #also microbiotics is the next huge frontier in treating depression and anxiety #(well they're tied for the next huge frontier with psychedelics probably) #good news #arguably lol #hope

[kairologia]

Houses in traditional astrology.

Instead of making separate posts for each house, I thought it’d be more judicious & practical to compile everything into one singular post for concision’s sake.

Some necessary contextualization before we get to the point:

— Most houses don’t represent personality traits or characteristics. They represent experiences & areas of your life. Your self in the more rudimentary sense of the term is the 1st house. Other houses can be other people, places, or experiences.

— The ascendant/1st house is you, not a “mask”, your “basic self”, a “facade” or a “superficial persona” it’s for the major part everything modern astrology believes the sun to be.

— The ascendant/1H representing you does not mean other placements cannot be relevant or resonant (as explained here), that’s an oversimplification and nothing in life is ever that simple. All elements in a chart matter, but to believe everything is a “me” indicators is far too reductive. This is especially relevant wrt appearance. While the 1H has higher than average chances of coming through when it comes to the visual aspect, there are other things that come into play — namely genetics, the Moon, the 2nd house, the IC, & the Ascendant Lord.

— There are 12 houses and 7 traditional planets. You will most certainly have empty houses — though inactive they are not. Even if there are no planets in a house, there will always be a planet ruling it and its themes will still hold significance to you & your life experiences, there just won’t be as much focus on them as there would be with houses containing planets.

— Signs don’t “naturally” rule houses. Aries does NOT signify the 1H unless you’re an Aries rising. In fact, “rulership” is something only planets can do. Not signs, not houses, just planets! The signs are a celestial system that shows HOW a planet’s energy expresses itself, whereas houses are a terrestial system that shows WHERE that energy is expressed (areas of life). You can read ABC house system debunks online, or wait for me to write one!

🪞 1st House 🪞

— Angular house

— Mercury’s joy

— “The Helm”

— Eastern horizon

— Horoskopos (hour marker)

— Inceptions

— Beginnings

— Life

— Body

— Appearance

— Personality

— Self & Identity

— Self Expression

— Vitality & Health

💰 2nd House 💰

— Succedent house

— “The Gate of Hades”

— Livelihood

— Prospects

— Desires

— Money & assets

— Physical posessions

— End of youth

— Financial affairs

— Time

— Value

— Materiality

— Ownership

— Sustenance

📜 3rd House 📜

— Cadent House

— The Moon’s joy

— “Goddess”

— Siblings

— Extended Relatives

— Short Distance Travel

— Religious sites & rites

— Places of worship

— Neighborhoods

— Small communities

— Communication & Writing

— School

— Learning

— Education

— Everyday life, routines

🪦 4th House 🪦

— Angular house

— Lowest angle of the chart

— “Subterranean”

— Family

— Parents

— Land

— Home & Property

— Privacy

— Secrets

— Roots & lineage

— Ancestry & genealogy

— Place(s) of Origin

— Inheritance

— The “past”

— Generational trauma

— Hidden treasures

— End of life

— Death & rituals surrounding it

— Endings

— Graveyards

— The Underground

🌹 5th House 🌹

— Succedent house

— Venus’ joy

— “Good Fortune”

— Romance

— Relationships

— Desire & Pleasure

— Praise & Worship

— Sexuality/Sex

— Creativity & Creation

— Art & artistic expression

— Children

— Charity

— Diplomacy & diplomats

— Pleasant pursuits & joy

— Gambling

🩸 6th House 🩸

— Cadent house

— Mars’ joy

— “Bad Fortune”

— Illness & Injury

— Health & Sickness

— Servitude

— Employees & subordinates

— Labor

— Work

— Sports

— Fighting

— Physical Harm

— Medical Professionals

— Herbalism & medicine

— Small animals & pets

⚖️ 7th House ⚖️

— Angular house

— “Setting” angle

— Marriage

— Spouse

— Partnerships

— Open enemies

— the “Other” (≠ of the self, the 1H)

— Commitments& agreements

— Confrontation

— Lawsuits

— Legal disputes

— Contracts

— Business

💸 8th House 💸

— Succedent house

— “Idle Place”

— Death & Endings

— Other people’s money & assets

— Debt

— Taxes

— Legacies

— Inheritance

— Grief

— Trauma

— Psychology & shadow work

— Shared resources & belongings

— Stagnation

— Fears

— Secrets

🔮 9th House 🔮

— Cadent house

— Joy of the Sun

— “God”

— Higher education & academic pursuits

— Pursuit of knowledge

— Teachers & professors

— Occult pursuits & faculties

— Religion

— Foreign places

— Long distance travel

— Pilgrimage

— Divination & Astrology

— Philosophy

— Dreams

— Prophecies

💼 10th House 💼

— Angular house

— “Midheaven”

— Highest angle of the chart

— Vocation

— Career

— Mother

— Fame

— Ambition & aspiration

— Recognition

— Influence

— The future

— Goals

— Social status

— Achievements

— Profession

— Public affairs

— Reputation

— Authority figures & leaders

— Government

— Social aspirations

🎉 11th House 🎉

— Succedent house

— Jupiter’s joy

— “Good Spirit”

— Friends

— Alliances

— Trust

— Emancipation

— Community

— Network

— Supporters & patrons

— Organizations

— Groups

— Mutual aid & support

🏥 12th House 🏥

— Cadent house

— Saturn’s joy

— ”Bad Spirit”

— Prior to birth: mother's labor

— Isolation

— Retreat

— Large animals

— Exile

— Rumors

— Misfortunes

— Envy

— Hidden enemies

— Betrayal

— (of Self or otherwise) Sabotage

— Mental health

— Restrictions

— Hospitals

— Incarceration

#astrology #astro notes #astrological observations #hellenistic astrology #astrological houses #houses in astrology #zodiac

[teresajoan]

Astrology: The relationship between the inner world and the outer world in a chart

"Our inner lives arise from our outer circumstances, and our outer circumstances arise from our inner lives"

When reading a chart, consider the lower horizon houses 1 to 6 versus the top horizon houses 7 to 12. Houses 1 to 6 are our inner experiences, whereas houses 7 to 12 are our outer projection and how we experience the external. An astrology chart is a wheel that is constantly spinning and moving energy around. Energy goes in one house and out the other.

The 3rd house and and the 12th house

Everyday thinking is influenced by the well-being of our subconscious. Vice versa, our conscious thought directs our subconscious and inner self how to feel.

The 9th house with the 3rd and 12th house

The 9th house is our ability to see the big picture. It assists us to be conscious of and understand our subconscious thoughts. It is essentially our ability to be able to have insight. This insight is what helps us to understand the relationship between the 3rd house, everyday thinking, and our subconscious, 12th house reactions, and patterns.

The 2nd house and the 11th house

The 11th house shows how we make money and what groups we attach ourselves to. The 2nd house shows what we do with the money we earn and how we attach ourselves to material items.

The 2nd house and the 8th house

As the 2nd house shows how we attach to our belongings (money and materials), the 8th house shows how other people's belongings attach to us. If money or belongings are inherited through the 8th house, the 2nd house shows how we spend that money or how we value that inherited item. Furthermore, the 8th house pulls us away from 2nd house concerns. As we deal with larger issues such as death, trauma, and transformation, we shed what we once held onto in the 2nd house and what we assign value to changes.

The 1st house (ascendent) and the 10th house (Midhaven)

How others see us in a public light affects how we see ourselves. As well as how we show up in the world influences public perception of ourselves.

The 1st house (ascendent) and the 7th house (descendent)

As the 1st house is our "personality" and how others experience us, the 7th house is how we experience the other, or how we see the "personality" of the other, be them partners or enemies. We can not perceive another without first having a grasp of who we are.

The 6th house and 12th house

As the 6th house is our health, as well as the house just below the horizon, it absorbs the energy coming in from the above 'external' houses. This is why our health can be impacted by so many things - relationships, work, mental health, and peers. It has a particularly strong relationship with the 12th house. The 12th house is just above the horizon, expelling energy from our inner self. The health of the 12th house can often manifest as physical illness in the 6th. As the 12th house is what we inherit through our family line in karma, so too is our health often inherited through our genetics.

The 5th house and the 11th house

The 5th house is what we do for joy and what brings us pleasure. Therefore, it influences the work we do and if we are able to find work that brings us joy in the 11th house. Also, consider how what we create is the 5th house is put out into the world for others to enjoy. Vice versa, what one creates is influenced by what they experience in the external world.

The 5th house and the 8th house

The 5th house is sex and pleasure. This energy is pushed out into the 8th house, which represents the orgasam. Traditionally, the 5th house was also representative of children, which would occur after merging of family energy (in-laws) in the 8th house.

The 4th house and all houses

The 4th house is our inner most self. At the core of us is all that we have experienced internally and externally. The 4th house is our roots. Where we come from will determine what path we take in life (10th house), what people we are drawn to (7th and 11th house), what loses and transformations we must suffer (8th and 12th house) and how we learn from them (9th house).

You can also follow me on Instagram @12thHouseFeels

#astrology #witchblr #astro observations #astroblr #11th house #3rd house #2nd house #5th house #8th house

[witchofthesouls]

How would a human’s body change after giving birth to a cybertronian hybrid? Some humans develop motion sickness after having a human baby, would a human get a higher heat tolerance after carrying a rodimus baby?

It varies from each mother, but each one definitely has these commonalities: small zones of metal platelets inside the uterus, an increased sensitivity towards Cybertronian presence, the ability to produce traces of Energon in breastmilk, and the necessity of greater amounts of essential metals and minerals.

The zones act as anchors for the newspark to latch and develop. The "tendrils" that connect the sparklet to the chamber are the sources where materials are funneled -the carrier's own frame and surrounding transfluid. It breaks it down to the basic building blocks for the sparklet's coding to initiate the construction process.

Unlike metal implants, these platelets are formed from living metal, so they don't trigger an inflammatory response or rejection. This is due to the living metal's ability to bridge to its "host" at its most basic components and essentially become an extension of the body rather than registered as a foreign substance. It meshed well with humans' own adaptability and extreme tolerances.

With the incorporation of living metal in their bodies, human carriers have a greater "sense" of nearby Cybertronians as well as a greater sensitivity of their moods via EM fields interacting with them.

The mechanism for how a human carrier is able to feed their own newspark is unknown. So far, there's a hypothesis that there's nanite cultures reinforcing their bodies and rewriting some aspects at a genetic level. It's supported by anecdotal accounts of human carriers recounting events of faster healing durations or receiving far less damage than anticipated as well as the documentation of their dietary needs and range during and after carriage. Many human carriers after birth still had issues with metals and minerals deficiencies, such as anemia, aching joints, muscle loss, and negative skin and hair changes. Ratchet (crossed with Autobot-aligned human medical personnel) noted it was corrected with far higher-than-recommended dosages (for the average human's) and higher caloric intake with no signs of toxicity or impacted health.

Some claim heightened senses, particularly sight, hearing, and smell. Other common complaints are hot flashes or higher base temperature, an urge to eat non-edible items, like metal coins and clay, heartburn, higher drug tolerance, skin and hair care changes, changing breast size, increased foot size, and restlessness. Surprisingly, many agree that sex, particularly penetrative, is better:

"Look, I thought the g-spot was a myth. Even (redacted) fancy sensors couldn't find mine, but after (redacted) popped out, it reset me. I'm a firm believer in it now. And all this weirdness is a perfect trade-off." - Audio recording from Ratchet, Autobot Chief Medical Officer of the Ark.

#ask #transformers #ratchet #cybertronian biology #pregnancy #bitlets #sparklings #tf headcanons #human bodies are fucking weird #especially when pregnancy in involved #maccadam #my thoughts #my writing #i need a tag for the hybrid biology posts 🤷‍♀️

[cinnamonnangel]

ASTRO 101 - THE HOUSES (PART I)

FIRST HOUSE - I AM

(The First House is ruled by Aries and Mars.)

The first moment you open your eyes to the world, first breath, first sight, first intention and first experience

General appearance, form and shape, physical body, general health, vitality and energy, action

Character, identity, self image, personality, mask, self interest, how others perceive you, self expression, independence, behavior, name, attitude, fame

How you see the world, how the world sees you

Spirit, life, ego, soul body

First impressions, beginnings

Head, face, eyes, blood, brain, muscular system

The moment of birth and people around you, place of birth and atmosphere, birth experiences, mother’s health and experiences during childbirth

SECOND HOUSE - I HAVE

(The Second House is ruled by Taurus and Venus.)

Material and non-material resources, attitude toward possessions,

How you make money or meet obligations, self worth

Personal finances, money matters, sense of value, stocks and share, trade, jewelry, documents, cash money, valuables, wealth, possessions, trade, material possessions, luxuries, banking activities, loans, economic situation, wares, rank, guarantee, financial security, artworks

Talents, comfort zone, security, self esteem, valuables, sense of values, resourcefulness, nutrition

Face, neck, throat, vocal cords, thyroid, metabolic system, voice and vocal talents

Economy, sovereign debt, colonies, fees, trade, banks, internal debts, artistic approaches of a country

THIRD HOUSE - I THINK

(The Third House is ruled by Gemini and Mercury.)

Conscious mind, memory, mental confusion, communication, intellect, mentation, thinking

Skillfulness, study, ability, writing, speaking, researching, learning, reading, perceiving, adaptability, ability to learn foreign languages

Depthless thoughts and informations, smattering

Elementary and primary education, puberty

Siblings, brothers, sisters, cousins, close relatives and neighbors

Short trips, tour, daily travel, neighborhood, public transports, vehicles, motorbike, cars, train, bus, boats, urban roads

TV, radio, telephone, computer, mails, messages, text, communication network and channels, short correspondence on social media, weather forecast

Shoulders, collar bone, arms, hands, fingers, lungs, nerves, the nervous system

Bookstore, library, school, post office, educational institution, streets, telephone kiosk

FOURTH HOUSE - I FEEL

(The Fourth House is ruled by Cancer and Moon.)

The place where we live with the family, home atmosphere, home life, house, mother, family, lineage, family matters, ancestry, custom, femininity

Subconscious, things we hide about ourselves, emotional problems, early childhood, depression, personal commitment, the deepest and the darkest point of the chart

Old age, the end of the life, diseases, grave

Land, realty, genetic heritage, underground sources

Chest, breaths, stomach, uterus, diaphragm, upper alimentary system

Agricultural enterprise, historical values, mining site, real estate, refuge facilities, farmers, cemeteries

FIFTH HOUSE - I WILL

(The Fifth House is ruled by Leo and Sun.)

Actions and activities we do for ourselves, things we like to do, hobbies, how do we spend our free time, creativity, activities we enjoy, pleasure, self expression, risk taking, leisure time, artistic talents,

Love, romance, dating, courtship, love affairs, the way we flirt

Children, birthing and creation, the character of our children

Acting, drama, dance, music, sports, artists, celebrities, stage

Games, cards, puzzles, fun, amusement, games of chance, gambling, speculative investment

Chest, upper back, heart, spine, cardiac system

Hotels, entertainment centers, casino, beauty shops, coiffeur, resort, amusement park, cinema, theatre, sports center, park, art exhibition

SIXTH HOUSE - I ANALYZE

(The Sixth House is ruled by Virgo and Mercury.)

What we do to survive, daily work, everyday routine, details, skills

Work routines, where we specialize our skills, workers, competition, employment, workmates

House of sickness, exhaustion, disease, allergies, health, physical body, physical condition

Issues that tire us and weaken us, drugs and addictions

Pets and animals

Abdomen, intestines, lower liver, alimentary canal, spleen, digestive nerves

Hospitals, health care providers, employees, service sector, trade unions, state employees, restaurants, food and beverage services, enemies, soldiers, police, military, army, security guard, navy, animal clinic

#astrology #aesthetic #birth chart #astro notes #astroblr #astroloji #astro natal #astro101 #zodiac #horoscope #firsthouse #second house #third house #fourth house #fifth house #sixth house #astro houses #aries #taurus #gemini #cancer #leo #virgo #astrology blog #girlblogger #mars #venus #mercury #moon #zodiac signs

[isabeljkim]

What the hell is going on with Day Ten Thousand:

Day Ten Thousand was weird enough that I felt like it deserved directors commentary, even though I’ve stopped explaining myself mostly except when I do.

Here’s a disclaimer before we begin: don’t read too much into it. I've noticed our culture wants to explain young womens’ art as some sort of public confessional booth and our current culture has a fetish for the autobiographical. Fuck that. I didn’t write three different POVs and three interlocking nonlinear narratives about the nature of storytelling as a psychic technology to be told that my writing isn’t a calculated Craft with a capital C. Now whether it is good Craft is a decision for you, not for me. 

Anyway. 

Day Ten Thousand is a satire of an Isabel story by way of Vonnegut pastiche. We’ll come back to this. 

I called Day Ten Thousand “psychoanalysis bait” on twitter so I shall put all my cards on the table so that your psychoanalysis is at least accurate. Note that these are only my cards, because other people deserve their privacy. I guess you could probably Google all of this but like, jeez. Don’t.

I had a pretty regular time in college except for the tangential deaths. 

When I was twenty, I was the opinion editor for my university newspaper and a girl who was a friend of a friend killed herself by walking in front of a subway. There was then a sort of a small suicide bubble which was a little bit public because we were an Ivy, and one of my opinion columnists was kinda suicidal, and I, without any training, ended up in charge of writing a front page editorial about the mental health crisis on campus on account of the dead kids, etc, and talk to administration about the dead kids. 

I hate talking about dead kids. Don’t ask me about it, or about the reporting. I don’t want to talk about it. 

The whole thing sucked shit and it’s why I’m a lawyer now and not a reporter. 

If this was a story that would be the only fact, but this is reality so I have to mention that a couple years later a guy I knew got literally hate crimed and murdered in a forest. I found out about that because I saw his friend crying in public and didn’t stop to ask what was wrong. Later I heard about this in the news, and realized my acquaintance had been Literally Fucking Murdered. A few months ago I had been arguing with him in the literary magazine editors meeting about whether a poem was good or not. I think he won that argument. Then he was murdered for being gay. 

These were my introductions to the specific emotion of “sometimes people die and you don’t feel like you get to feel bad about their deaths and you still think about it a couple times a month seven years later.” 

You can probably guess where the subject material of this story came from.

Day Ten Thousand was a story about inevitable deaths, and the difference between a death in a story and a death in reality, and about…the way a death marks a narrative and a real life and how it becomes fictionalized over time. I also saw a clean way to finally do my deep time / far future story, which was something I had been thinking about on and off for a couple of years (the original version was about a shaman in the deep-time era who has a vision about having to do a murder re: preserving genetic material for the future, but it never really gelled in a way that made sense). 

I had also been wanting to write something a little metafictional, because I felt like I was writing the same story over and over (if you’ve noticed my stuff getting weirder, that’s why. I was on a bit of an experimentalist kick late last year and early this year). 

So it’s a satire of an Isabel story. I’m self-aware enough to note my obvious recurring motifs: time travel, dead people, grief, people who have a weird relationship to each other, a third-act twist, the tendency to punctuate with in-universe facts to imply emotion, to tell x in order to show y, egregious and blatant use of the second person. And then there’s the stuff that you wouldn’t know, but I do: I dislike writing in the first person, I wanted to do something nonlinear, I think a lot about stories about stories, about the idea of a story as a technology, I find myself dropped into recursive fate-like thought patterns. So a lot of this story is both my self-deprecating poking fun at myself and my habits, and also my thesis statement about…what is the point of fiction if not to make sense of the past and the future, I suppose.

The reason it is a Vonnegut pastiche is because I like Vonnegut a lot and I was trying to do something Slaughterhouse-5-ish with drastically less fucked source material. Sorry Kurt. 

There are three stories happening in Day Ten Thousand, and a secret fourth story. Each story is a suicide loop. The protagonist is trying to break a specific loop by telling a story. This story is about accepting what you have to, and changing what you can. This is a story about letting go and also not letting go. The emotional range of each narrative affects the other psychically, because by changing the vibe of the metanarrative, the individual narratives are allowed to change. 

The story in the archaic is a story that is being told postmortem, it is all hypotheticals based on fact. The story in the future is a singular narrative happening in real time until it isn't. And the story in the present is a guy telling the story about the future, which requires him to tell the story about the past as well, and mostly what Dave is doing here is avoiding the question, but it reflects how Dave thinks about the girl dying in front of the train. 

Does that make sense? No? That’s fair. That’s a postmortem explanation of what actually happened. What actually happened is that I rewrote Day Ten Thousand six times, each time more frustrating than the last, each time with the neutral-ish narrator taking up more and more air. And over time the narrator became a participant, and that’s what created the secret fourth story between “you” and the narrator. 

I had thought there were only three loops that needed to be escaped - the past (archaic, pinned story), and the future (space station, mutable fact), and that the present (the narrator’s world) was something that was static (pinned fact). After all, the girl’s already dead. She’s already stepped in front of the train. 

But the narrator isn’t doing so hot. The narrator is also Dave. And the narrator is telling the story to someone. Somewhere between version one and version six, I realized the only version of this story that makes sense is the one where the story is a conversation, and that you and I, as the narrator and the person at the other end, were also in a loop. 

So. That's whats happening.

I’m not sure if I love the ending. But I rewrote it six times and this one felt as final as it is going to get. I am done reinventing the fucking wheel. You know how it is with spaghetti. Promise I’ll write you something normal next time, I think I’ve gotten the avant- garde out of my system for a few months. 

And hey, I know I said all cards on the table but people deserve their privacy and that includes the kid i used to be when I was twenty, sitting in the shitty little windowless opinion column office, writing about suicide. 

Anyway. Day Ten Thousand is about stuff and things. Themes. So it goes. 

Thanks for reading. I’ll see you later. 

If that was too depressing for you, here are some fun facts: 

The main character is Dave after 2001: A Space Odyssey because I had wanted to make a “I’m sorry Dave I can’t do that” joke, but I couldn’t shove it in :( 

I just thought that phlebotomist was a funny word but I also fucked myself because I misspelled it every time. 

I reread half of Slaughterhouse Five to write this but then my copy got returned to the library automatically so I didn’t finish it. (yes, I’ve read it before, like three times)  

I took one single evolutionary anthropology course in college and it shows.  

I did end up looking at the wikipedia page for “the wheel” for this and then wondering exactly what I was doing with my life. 

About half the facts in this are real, and I read a couple of papers for a couple of things in it (that I promptly then ignored), but the rockets-rome-horse’s ass thing is specifically a story that my friend Max H. likes to tell. 

[gallifreyinstituteforlearning]

Is it possible for two Time Lords from different houses to loom a child together? Would it pose a threat to the loomling's health? Which House would the said loomling belong to?

Inter-house Reproduction

🧬 Feasibility

It's technically possible for Time Lords from different Houses to combine their genetic material in a loom. The looms, after all, are just there to take biodata models and turn them into people. There's no health risk to the loomling due to the cross-House genetics, as the loom can't produce something from biodata that isn't viable and - shock/horror - Gallifreyans of all classes and social standings are the same at the most basic level.

🏡 House Affiliation

The House affiliation of the loomling is a bit more complicated. It would likely depend on several factors:

Loom Origin: The parents need to decide which House's loom they're going to use. This is important, as the child will take on that House's biological affiliation, including the markers and maybe some traits.

Parental Influence: The dominant House of the contributing parents might play a role. If one parent's House has a more substantial influence or standing, the parents might decide to have them affiliated with that House.

Political Considerations: The decision could also be influenced by political manoeuvring or agreements between the Houses involved.

🚫 Taboo and Politics

The union of two different Houses to produce a loomling could stir up some political and social tensions. There could be concerns about blending lineages, sharing secrets or traits unique to each House, or even upsetting the balance of power. This act could be seen as a powerful symbol of unity or a contentious move, depending on the Houses involved.

Hope that helped! 😃

→🫀Gallifreyan Anatomy and Physiology Guide (WIP) →⚕️Gallifreyan Emergency Medicine/Monitoring Guides →📝Source list (WIP)

-------------------------------------------------------

》📫Got a question / submission? 》😆Jokes |🫀Biology |🗨️Language |🕰️Throwbacks |🤓Facts 》📚Complete list of Q+A 》📜Masterpost If you like what GIL does, please consider buying a coffee or tipping below to help make future projects, including complete biology and language guides.

#doctor who #gil #gallifrey institute for learning #dr who #dw eu #gallifrey #gallifreyan biology #gil biology #gallifreyans #ask answered #zephyrd17

[pumpkincurryelote]

Furthering the world-building thought experiment of Midwives as an independent organization or governing body in a stateless/moneyless world: Imagine their purview extending not just to birth, but to abortion, women's health, women's history, and women's liberation by force where necessary up to and including the execution of rapists. Exclusively female membership, living in facilities akin to non-religious convents. In fact the most powerful of any large organization. How their services/protection might be engaged would vary depending on region. If this be a post-patriarchy world, they would be the first line of defense against the resurgence of said disease.

Farmers would be second most powerful. As permaculturists in a world where everything is locally sourced, and they would be responsible for protecting biodiversity of both flora and fauna in their biomes. There is no mass production of anything in this model. Wild animals are respected members of the community alongside domesticated ones. They monitor and survey the land, on guard for outbreaks and potential disasters, tending the food forests and keeping the biome healthy. They deliver non-human medical care to every creature in the land. Their voices are heard first on the floor of any development project and they can set hard boundaries or veto projects outright. While not explicitly stated to be female only, females would nonetheless outperform males in this field. Even in hunting.

Next up is Libraries. Librarians collect, organize, and administer all manner of public resource, not just books. Knowledge, tools, furniture, clothes, technology, seeds, genetic material, whatever is needful. They keep mundane records of everyone in their community, and community members can deposit personal logs for safekeeping here. Indeed anything the community deems of utmost value may be stored here. Every library is built to withstand assault, and to protect its contents-- a last resort lockdown would fully seal the library from the outside world for 100 years, killing anyone inside. The identities of chief librarians with access to sensitive collections (and the ability to lock their library down) are shrouded in secrecy. Field librarians go out on expeditions to collect data, specimens, etc where permitted by a region's Farmers (and always with a Farmer in attendance).

Hospitals are fourth, and we all know what they're supposed to do. Universities are arguably fifth, and bosom buddies with Libraries. Universities would be the only "large cities" you ever see, and are major transportation hubs. Any large scale project happens here-- rocket to the moon large. Trains occupy this status bracket as well, being the main arteries of civilization/transportation. Ocean cargo could be an extension or a symbiotic relationship.

Of equal influence are Mail and Sanitation. The postal service delivers through whatever means necessary. Any interference with another person's mail results in brutal application of force. No matter how isolated or alone you think you are, the post service will find you. If anybody at all sends you a message, you WILL receive it. They're the best trackers in the world. Many have working dogs as companions. Some have birds. All of them tend to be loners unless someone has done them dirty or behaves dishonorably.

Sanitation encompasses recycling/repurposing of non-compostable goods, composting itself (composting toilets are the norm), janitorial work, pandemic/outbreak containment, and burials (where applicable). If there's a landfill or old oil spill that needs remediation, they're there. Many have skill in repairs/fabrication, and choose this life to have first pick of scavenged parts. Many are also skilled at soapmaking, extractions (Greek oregano, eucalyptus, wintergreen, etc.), and distillation (vinegar).

#radblr #radfem safe #solarpunk #anti capitalism