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fatehbaz · 9 months

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Didn't wanna clog up your post, and these sources are more about relationships of time with space/place, but here's some stuff that I've encountered:

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“Temporal sovereignty”. Contemporary US/Australian claims over time-keeping. Reclaiming agency by operating on Indigenous/alternative time schedules. The importance of the “time revolution” in the Victorian era to Euro-American understandings of geology and deep past, precipitating nineteenth-century conquest of time. Mid-twentieth century understanding of “deep time” and its co-option by the Australian state. "Deep time dreaming".

Laura Rademaker. “60,000 Years is not forever: ‘time revolutions’ and Indigenous pasts.” Postcolonial Studies. September 2021.

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How "time is a form of enclosure". Checkpoints, "baroque processes to apply for permits to travel", fences, incapacity to change residences, and other "debilitating infrastructures" work to "turn able bodies into a range of disabled bodies" by "stretching time". This is a "slow death" and a simultaneous "slowing down of life" because "it takes so long to get anywhere" and "movement is suffocated". Thus "time itself is held hostage". This "suspended state" of anxiety and endless wait-times "wreaks multigenerational psychological and physical havoc". "Checkpoints ensure one is never sure of reaching work on time. Fear of not getting to work then adds to the labor of getting to work [...]. Bodies in line at checkpoints [...] [experience] the fractalizing of the emotive, cognitive, physiological capacities" through a "constant state of uncertainty". "The cordoning of time through space contributes to an overall 'lack of jurisdiction over the functions of one's own senses' [...] endemic to the operation of colonial rule". This "extraction of time" produces a "depleted" and tired person "beholden to the logistics" of administrative apparatuses, community suffers and "communing is thrawted".

Jabir K. Puar. "Spatial debilities: Slow Life and Carceral Capitalism [...]." South Atlantic Quarterly 120. April 2021.

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The "apocalyptic temporality" that presumes extinction. Indigenous Polynesian/Pacific perceptions and ways of being "destabilize the colonial present" and also "transfigure the past" by "contesting linear and teleological Western time". Indigenous "ontologies of cyclical temporality or inhabitation of heterogenous time". How United States and Europe colonized Oceania for weapons testing and conquest of tropical Edens while rendering local Indigenous people "ungrievable" and "without future". "Pacific time is a layering of oral and somatic memory". Instead of accepting an apocalyptic future or doomsday or nightmare, assert the possibility of a livable future, in spite of "Western temporal closures".

Rebecca Oh. “Making Time: Pacific Futures in Kiribati’s Migration with Dignity, Kathy Jetnil-Kijiner’s Iep Jaltok, and Keri Hume’s Stonefish.” MFS Modern Fiction Studies. Winter 2020.

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Colonial "space-time homogenization". The experience of "homogenous, empty time". Orientalist "time lag" and the naturalization of a supposed East-West hemispheric divide. Late Victorian imperial conceptions of temporality. The British establishment of the Greenwich meridian and International Date Line. The influence of British imperial seafaring and cartography on the establishment of time and on European/US feelings towards the Pacific Ocean. How the origin of English science fiction literature, space travel aspirations, and time travel narratives coincided with the Yellow Peril and xenophobia targeting East Asia.

Timothy J. Yamamura. "Fictions of Science, American Orientalism, and the Alien/Asian of Percival Lowell". Dis-Orienting Planets: Racial Representation of Asia in Science Fiction. 2017.

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Imprisonment as time-control. Here “the question of the past the present and the future indeed time itself looms” especially around the prisoner. “The law renders punishment in units of time”, taking away a the right to a future. There are alternative worlds, many of them, which have been practiced and brought into being, which colonization tried to obscure. There is “a whole anthropology of people without future embedded in the assumptions that justify mass imprisonment as poverty management”. "The prison’s logic exterminates time as we know it”. In prison, bodies have been alienated from time and history ... the punishment seems endless ... to “achieve a measure of agency and possibility it is necessary to redeem time”, to refuse the doom, fated to a life of abandonment.

Avery Gordon. “Some Thoughts on Haunting and Futurity.” borderlands. 2011.

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Bursting the Limits of Time: The Reconstruction of Geohistory in the Age of Revolution (Martin J.S. Rudwick, 2010) explores how the advent of European sciences like geology, preceding the "time revolution" when Europeans experienced revelations about the scale of "deep time", happened alongside and after the Haitian Revolution and other abolitionist movements. French, German, and British naturalists translated the explosion of "new" scientific knowledge from the colonies, so that the metropolitan European audience became a market for historical and scientific "narratives" about how "nature" and time functioned.

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Prartik Chakrabarti's writing on time, temporality, and "the deep past" as British imperial concepts built in conversation with colonial encounters with South Asia. (British Empire reaching such heights in the middle of the nineteenth century at the same time that the newly professionalized sciences of geology were providing revelations about the previously unknown vast scale of "deep time". New colonial anthropology/ethnology also presumed to connect this "primitive" past with "primitive" people.)

See Chakrabarti's "Gondwana and the Politics of Deep Past". Past & Present. 2019.

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We must witness and consider "multiple space-times" to understand how "unfree labour" of plantations was "foundational" to contemporary work, movement, subjugation, health, etc. We must "trace the geneaology of contemporary sovereign institutions of terror, discipline and segregation" [workplaces, imperial/colonial nations, factories, mines, etc.] back in time to plantations. How "the [plantation] estate hierarchy survives in post-plantation" times and places, with the plantation "being a major blueprint of socialization into [contemporary] work". The plantation was "a laboratory for [...] migration regulation in subsequent epochs" that practiced methods of racializing and criminalizing.

Irene Peano, Marta Macedo, and Colette Le Petitcorps. "Introduction: Viewing Plantations at the Intersection of Political Ecologies and Multiple Space-Times". Global Plantations in the Modern World: Sovereignties, Ecologies, Afterlives. 2023.

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“Slow life” and the relationship between “settler colonialism, carceral capitalism, and the modulation of ... registers of time,” including “historical time, the stealing of time through the expansion of labor time, ... and the cordoning off of space through time”. For example, as in occupied zones or at border checkpoints, “the cordoning off of space through time” includes physical architecture like fences and customs, obstacles that impede movement and rhythm, so that “nothing ever happens on time” and there is “a stretching of time”. All the wasted time spent in line, showing papers, waiting for confirmation, etc. “is not a by-product of surveillance, it is the point of surveillance”. Such that “uncertainty becomes a primary affective orientation ... flesh as felt” with a racializing effect“. "This is a biopolitics conditioned through pure capacitation and its metrics”:

Jasbir Puar. In: “Mass Debilitation and Algorithmic Governance” by Ezekiel Dixon-Roman and Jasbir Puar. e-flux Journal Issue #123. December 2021.

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"Starfish time". Indigenous Australian/Aboriginal perceptions of time and "attending to more-than-human agencies of time". Acknowledging the timescales of entire ecosystems, as part of multispecies relationships, a "transcorporeal collaboration". Cyclical time vs linear time. Contrasting timescales experienced by insects that only live a few days and creatures that live for decades. "Starfish may seem to be still" but they slowly move; "larval time" and "the time it takes for eggs to develop and hatch"'. The "immensity of the alterity is literally incomprehensible"; "we can't know what these beings know" but we "should seek respect and be aware of how our lives are entangled".

Bawaka Country including, S. Wright, S. Suchet-Pearson, K. Lloyd, L. Burarrwanga, R. Ganambarr, M. Ganambarr-Stubbs, B. Ganambarr, D. Maymuru. “Gathering of the Clouds: Attending to Indigenous understandings of time and climate through songspirals.” Geoforum. January 2020.

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The use of calendars, dates, clocks, and industrial/corporate temporality as fundamental to the rise of plantations and financialization in United States/Europe, with a case study of the modern Colombian/Latin American state. Observance of certain dates and strict adherence to specific calendars support "mythologized deeds and heroic retellings" of colonization and industrialization. “The evolution and internalization of disciplined concepts of time” were intimately tied to the rise of wage labor in industrializing England and later during the global ascendancy of work and industrialized plantation monoculture, but the persistence of alternative time should “serve as a reminder that futures and the demarcation of epochs are never as simple as a neatly organized calendar”.

Timothy Lorek. “Keeping Time with Colombian Plantation Calendars.” Edge Effects. April 2020.

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Indigenous people of Alaska and the US control over time management. For the past 50 years, Yupiak people have been subject to US government’s “investment in a certain way of being in time” which “standardized the clock” and disrupted human relationships with salmon. This US management model “anonymized care” and made “a way of attending to the life and death of others that strips life of the social and ecological bonds that imbue it” with resilience and meaning, which “ignores not only the temporality of Yupiaq peoples relations with fish, but also the human relations that human-fish relations make possible”. This disregards “the continuity of salmon lives but also the duration of Yupiat lifeworlds ... life is doubly negated” ... “futures depend on an orientation to salmon in the present”.

William Voinot-Baron. “Inescapable Temporalities: Chinook Salmon and the Non-Sovereignty of Co-Management in Southwest Alaska.” July 2019.

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"Idling" and "being idle" as a form of reclaiming agency and life. Case studies of fugitive Blackness in Caribbean plantation societies. “Disruptive waiting”. “The maroon’s relationship to time challenges [both] the totalizing time of the modern state, but also the [...] narratives to negotiate struggle in the [...] present" in "antagonistic relationship with colonial power". Defying the “European narrative of modernity”. Refusing to be productive.

Amanda Lagji. “Marooned time: disruptive waiting and idleness in Carpentier and Coetzee.” Safundi: The Journal of South African and American Studies. March 2018.

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Indigenous futures. "It is important to remember that some futures never went anywhere" and "yet they survive. These are futures suppressed and cancelled by colonial power." These are "parallel futures". "Colonial power must control the past so as to deny the emergence of" an alternative future; "colonial power creates a future in advance so that no others will take its place". Poor, racialized, Black, Indigenous people manifest alternative futures.

Pedro Neves Marques. "Parallel Futures: One or Many Dystopias?" e-flux. April 2019.

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The "legacy of slavery and the labor of the unfree shape and are part of the environment we inhabit". The "idea of the plantation is migratory" and it lives on "as the persistent blueprint of our contemporary spatial troubles", so we must seek out "secretive histories" that no longer "rehearse lifelessness".

Katherine McKittrick. “Plantation Futures.” Small Axe. 2013.

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“The temporal dispossession” of Congolese people. There is an “impossibility” of “predictable time” because temporal dispossession “disrupts the possibility of building a future”. Livelihoods/income is driven by market and price fluctuations in United States and Europe tech industries, so “there is an inescapable day-to-day sense of uncertainty”. As Mbembe says, “in Africa, the spread of terror ... blows apart temporal frames”.

James H. Smith. ‘Tantalus in the Digital Age: Coltan ore, temporal dispossession, and “movement” in the Eastern Democratic Republic of the Congo.’ American Ethnologist Volume 38 Issue 1. February 2011.

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“Slow death”. Chronic illness not just as a byproduct of colonialism/dispossession, but also as part of its aim, a weapon that debilitates people, who become exhausted. Dooming poor and racialized people to lives “without future” through debility, “a condition of being worn out”. Relationship of illness, lack of healthcare, and debt as functionally incapacitating, a form of death sentence. A “zone of temporality” unfolding unlike abrupt/sudden traumatic events and becoming an inescapable condition.

Jasbir K. Puar. The Right to Maim: Debility, Capacity, Disability. 2017.

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The extension of poverty, landlessness, homeless, and imprisonment. "To be unable to transcend the horror of such a world order is what hell means", and "without a glimpse of an elsewhere or otherwise, we are living in hell". The utopian is not only or merely a “fantasy of” and for “the future collectivity” but can be claimed and built and lived here, now. There is "no guarantee" of “coming millenniums or historically inevitable socialisms”, no guarantee that “the time is right” one day if we wait just long enough. Instead: "can a past that the present has not yet caught up with be summoned to haunt the present as an alternative?" The "utopian margins", an alternate world crossing time and place, an "imaginative space and temporality to trace the remains of what "was almost or not quite, of the future yet to come", living as if it were the present. Colonialism tried to crush the many headed hydra of the revolutionary Atlantic, those who challenged the making of the modern world system.

Avery F. Gordon. As interviewed by Brenna Bhandar and Rafeef Ziadah. “Revolutionary Feminisms: Avery F. Gordon.” As transcribed and published online in the Blog section of Verso Books. 2 September 2020. And: Avery Gordon. “Some thoughts on the Utopian.” 2016.

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The US/European "city is the site of regulatory regimes" that try to impose a definitive narrative about history, progress, and possible futures. But it cannot achieve "a wholly Apollonian, seamlessly regulated realm" because the land "continues to be haunted by the neglected, the disposed of, the repressed". The "commodification" of landscapes "circulates an imaginary geography" mediated through advertisements, labels, soap operas, television, etc. which celebrate "sanctioned narratives and institutionalized rhetoric". A "wild zone" of informal spaces, debris. "Ruins are places where the things, people, and "other memories can be articulated". There is "a spectral residue" that "haunts dominant ways of seeing and being". "Alternative stories might be assembled", so that we can respect the people banished to abandonment, the periphery, and reclaim agency.

Tim Edensor. “The ghosts of industrial ruins: ordering and disordering memory in excessive space.” Environment and Planning D: Society and Space volume 23. 2005.

Also, how "master narratives of history as progress decompose" when faced with "a continuously remembered past" when "the ghosts of this past rear up in the ruin" to expose "the debris of unprecedented material destruction" of colonialism/empire-building. These "hauntings rupture linear temporality" and recall those people beaten down as "the trash of history". It is "essential to see the things and the people [...] banished to the periphery [...]."

Tim Edensor. "Haunting in the ruins: matter and immateriality". Space and Culture Issue 11. 2002.

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"Many kinds of time" of bacteria, fungi, algae, humans, and "Western colonialism meet on the gravestones". Some creatures, like lichen, are very long-lived and "these temporal feats alert us that modernity is not the only kind of time, and that our metronomic synchrony is not the only time that matters". The "long duree evolutionary rapprochements to the quick boom and bust of investment capital" where "minor forms of space and time merge with great ones". Extinction is "a breakdown of coordinations with reverberating effects". Ghosts remind us that we live in an impossible present, a time of rupture. "Deep histories tumble in unruly graves that are bulldozed into gardens of Progress". "Endings come with the death of a leaf, the death of a city, the death of a friendship".

Elaine Gan, Anna Tsing, Heather Swanson, and Nils Burbandt. “Introduction: Haunted Landscapes of the Anthropocene.” Arts of Living on a Damaged Planet: Ghosts and Monsters of the Anthropocene. 2017.

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Everywhen: Australia and the Language of Deep History. (Edited by Ann McGrath, Laura Rademaker, and Jakelin Troy. 2023.)

Chapters include: "Bugarrigarra Nyurdany, Because of the Dreaming: A Discussion of Time and Place in Yawuru Cosmology" (Sarah Yu et al.); "Songs and the Deep Present" (Linda Barwick); "Yirriyengburnama-langwa mamawura-langwa: Talking about Time in Anindilyakwa (James Bednall); "Across 'Koori Time' and Space (John Maynard)

#im sorry i guess i accidentally deleted this post so here it is again #colonial #imperial #temporality #abolition

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tanadrin · 7 months

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So besides "all religion is a pathetic cope" what exactly is the point of all your recent posting?

Religion isn't a pathetic cope! Religion is fundamentally hard-wired into who we are. This is something both Dan McClellan and David Bokovoy talk about quite cogently: we are evolved to detect agents in the world around us, that agency-detection mechanism errs on the side of false positives rather than false negatives (bc false negatives tended to get eaten), and that plus other cognitive systems like our relentless pattern-matching ability and our capacity for theory of mind produce some quite complex intuitions about the world, out of which a sense of the supernatural almost inevitably falls.

Dan McClellan in his interviews on Mormon Stories in particular talks about the cognitive science side of religious studies, and the experiments done to try to get at the underlying intuitions, and he points out that in these experiments it becomes pretty evident that both atheism and the more philosophically complex forms of religion most readers of this post are probably accustomed to are the result of highly reflective attitudes toward the world; the intuitive sense of supernatural agency tends to ascribe very humanlike qualities to supernatural agents--I am reminded of some of the stuff @transgenderer has posted about the Mbuti and the Ainu and their beliefs in a parallel "spirit world" that is very much like our own, where the spirits live lives very similar to the ones we do.

When you add in the ways that religion taps into other important human social functions--collective mythmaking, social organization, the creation of networks of trust and reinforcement of particular identities--it becomes clear that religion is something which fulfills what are for many people important psychological needs, and that (in some form) we will always have something like religion with us. Now, "religion" itself is kind of a tricky category--in religious studies it is apparently accepted as a truism that "religion" is just "anything we call a religion," because it lumps together what are often some quite heterogeneous phenomena, and the original formation of the category was in discourse by mostly-Protestant Europeans trying to understand the cultures and traditions of the rest of the world mostly with reference to (again, mostly Protestant) Christianity. So as long as we're aware that this is a very loose category, and everything above has to be taken mutatis mutandis so far as it applies to individual members of the category, we can talk carefully about religion in general terms.

Dan McClellan, David Bokovoy, and the guy who originated the application of cognitive theory to the study of religion are all religious. So clearly they don't see religion as cope, or as this perspective as one that necessarily implies religion is cope.

What would be pathetic is someone who cannot tolerate the existence of an outside view of religion, either because it causes them to doubt truth claims of that religion in ways that make them uncomfortable (because the truth of that religion is deeply integrated into their personal sense of identity), or because they can only read differing viewpoints as a hostile attack, and who then sends aggressive anons to strangers on the internet as a result. That would in fact be the kind of thing that only someone with really profound insecurities that they are unloading on other people does, because they don't have the strength to deal with those insecurities themselves.

#i didn't even say organized religion is a cope #i did say it fucking sucks #but that's a moral judgement

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compneuropapers · 8 months

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Interesting Papers for Week 37, 2023

Population dynamics of head-direction neurons during drift and reorientation. Ajabi, Z., Keinath, A. T., Wei, X.-X., & Brandon, M. P. (2023). Nature, 615(7954), 892–899.

Distinct roles of forward and backward alpha-band waves in spatial visual attention. Alamia, A., Terral, L., D’ambra, M. R., & VanRullen, R. (2023). eLife, 12, e85035.

Landmark-based spatial navigation across the human lifespan. Bécu, M., Sheynikhovich, D., Ramanoël, S., Tatur, G., Ozier-Lafontaine, A., Authié, C. N., … Arleo, A. (2023). eLife, 12, e81318.

Subjective signal strength distinguishes reality from imagination. Dijkstra, N., & Fleming, S. M. (2023). Nature Communications, 14, 1627.

Measuring cognitive effort without difficulty. Fleming, H., Robinson, O. J., & Roiser, J. P. (2023). Cognitive, Affective, & Behavioral Neuroscience, 23(2), 290–305.

Coding of object location by heterogeneous neural populations with spatially dependent correlations in weakly electric fish. Haggard, M., & Chacron, M. J. (2023). PLOS Computational Biology, 19(3), e1010938.

Identifying causal subsequent memory effects. Halpern, D. J., Tubridy, S., Davachi, L., & Gureckis, T. M. (2023). Proceedings of the National Academy of Sciences, 120(13), e2120288120.

THINGS-data, a multimodal collection of large-scale datasets for investigating object representations in human brain and behavior. Hebart, M. N., Contier, O., Teichmann, L., Rockter, A. H., Zheng, C. Y., Kidder, A., … Baker, C. I. (2023). eLife, 12, e82580.

Severely Attenuated Visual Feedback Processing in Children on the Autism Spectrum. Knight, E. J., Freedman, E. G., Myers, E. J., Berruti, A. S., Oakes, L. A., Cao, C. Z., … Foxe, J. J. (2023). Journal of Neuroscience, 43(13), 2424–2438.

Speed-accuracy tradeoffs in decision making: Perception shifts and goal activation bias decision thresholds. Larson, J. S., & Hawkins, G. E. (2023). Journal of Experimental Psychology: Learning, Memory, and Cognition, 49(1), 1–32.

Adaptive tuning of human learning and choice variability to unexpected uncertainty. Lee, J. K., Rouault, M., & Wyart, V. (2023). Science Advances, 9(13).

Robust deep learning object recognition models rely on low frequency information in natural images. Li, Z., Ortega Caro, J., Rusak, E., Brendel, W., Bethge, M., Anselmi, F., … Pitkow, X. (2023). PLOS Computational Biology, 19(3), e1010932.

The temporal dynamics of the Stroop effect from childhood to young and older adulthood. Ménétré, E., & Laganaro, M. (2023). PLOS ONE, 18(3), e0256003.

Capacity Limits Lead to Information Bottlenecks in Ongoing Rapid Motor Behaviors. Moulton, R. H., Rudie, K., Dukelow, S. P., Benson, B. W., & Scott, S. H. (2023). ENeuro, 10(3), ENEURO.0289-22.2023.

Stimulating human prefrontal cortex increases reward learning. Overman, M. J., Sarrazin, V., Browning, M., & O’Shea, J. (2023). NeuroImage, 271, 120029.

Theta-gamma phase amplitude coupling in a hippocampal CA1 microcircuit. Ponzi, A., Dura-Bernal, S., & Migliore, M. (2023). PLOS Computational Biology, 19(3), e1010942.

A dynamical model of C. elegans thermal preference reveals independent excitatory and inhibitory learning pathways. Roman, A., Palanski, K., Nemenman, I., & Ryu, W. S. (2023). Proceedings of the National Academy of Sciences, 120(13), e2215191120.

Targeting neural correlates of placebo effects. Romanella, S. M., Mencarelli, L., Burke, M. J., Rossi, S., Kaptchuk, T. J., & Santarnecchi, E. (2023). Cognitive, Affective, & Behavioral Neuroscience, 23(2), 217–236.

Disturbances in primary visual processing as a function of healthy aging. Springer, S. D., Erker, T. D., Schantell, M., Johnson, H. J., Willett, M. P., Okelberry, H. J., … Wilson, T. W. (2023). NeuroImage, 271, 120020.

Interaction between Theta Phase and Spike Timing-Dependent Plasticity Simulates Theta-Induced Memory Effects. Wang, D., Parish, G., Shapiro, K. L., & Hanslmayr, S. (2023). ENeuro, 10(3), ENEURO.0333-22.2023.

#neuroscience #science #research #brain science #scientific publications #cognitive science #neurobiology #cognition #psychophysics #neurons #neural computation #neural networks

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neverfakeautism · 11 months

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Facial features provide clue to autism severity

by Deborah Rudacille / 20 October 2011

Boys with autism have a distinct facial structure that differs from that of typically developing controls, according to a study published 14 October in Molecular Autism1. Specifically, boys with autism have broader faces and mouths, flatter noses, narrower cheeks and a shorter philtrum — the cleft between the lips and nose — compared with controls, according to the three-dimensional facial imaging system used in the study. These distinctive features suggest that certain embryonic processes that give rise to facial features are perturbed during development, the researchers say.

The participants in the study were all 8 to 12 years old, an age range during which the face is relatively mature, but not yet affected by the hormonal changes of puberty.

The researchers used the imaging system, dubbed 3DMD, to plot 17 ‘landmarks’ or coordinates on the face of 64 boys with autism and 40 typical controls. They then measured the distance between several of these coordinates.

Boys with autism who have the most distinctive facial features cluster into two groups with very different sets of autism symptoms, the researchers found.

Boys in one group tend to have wide mouths, combined with a short distance between the top of the mouth and the bottom of the eyes. They also show severe symptoms of autism, including language impairment, intellectual disability and seizures.

By contrast, those in the second group have broad upper faces and a short philtrum. They are more likely to be diagnosed with Asperger syndrome, and to have fewer cognitive impairments and language difficulties compared with the first group.

“As a clinical geneticist, I have always been impressed by a certain facial phenotype in children with autism,” says lead investigator Judith Miles. But it wasn’t until she turned to 3DMD, developed for use by plastic surgeons, that clear quantitative differences emerged between boys with autism and controls, she says.

Those differences almost certainly reflect underlying neurodevelopmental processes, she says. “The reason to look at the face is that it reflects differences in the brain.”

Group effects:

Studies have found that children with autism are more likely than controls to have dysmorphology, or unusual physical features, of the head and skull.

Earlier this month, researchers at the University of South Alabama reported that among children referred for genetic testing for suspected autism, those who have a copy number variation (CNV), a deletion or duplication of a genetic region, are more likely to have unusual facial features than those who carry no CNVs2.

“There is remarkable etiologic heterogeneity in autism, and the use of dysmorphology phenotyping may help us come to grips with some of this complexity,” says Curtis Deutsch, associate professor of psychiatry at the University of Massachusetts Medical School, who was not involved with either new study.

Studies of facial dysmorphology in autism have generally relied on observation or tools such as calipers to pinpoint specific facial features.

3DMD instead uses multiple digital cameras to capture a 360-degree image of the head. Algorithms integrate the images to produce a single 3D image that is analyzed using special software.

This generates results that are more fine-grained than manual measurements, says Kristina Aldridge, assistant professor of pathology and anatomical sciences at the University of Missouri.

“We’re not talking about kids you would pick out on the street as looking different. These are subtle differences that are systematic, [in the range of] 2 to 5 millimeters,” Aldridge says. “It is extraordinarily precise.” She has used 3DMD to assess facial dysmorphology in children with birth defects3.

Deutsch has used the same technology in his own research. Still, he cautions that the sample size in the study may not be large enough to generate reliable results.

“It is also important to guard against performing a multitude of statistical tests without appropriate corrections,” he adds. “Otherwise differences that are reported as significant can result from chance alone.”

Researchers typically apply mathematical formulas to correct for chance associations. Miles instead used cluster analysis, which pulls together similar entities from large datasets.

This sort of analysis can produce results that are difficult to interpret, Miles says. “It will always give you something, but we had to look at whether clinical differences correlated with the subgroups identified by the cluster analysis.”

Using autism diagnostic characteristics, intelligence quotients (IQ), medical symptoms and other measures, she says, “what we found is that those two subgroups really do appear to be discrete clinically.”

The findings resonate with researchers who have studied dysmorphology in autism using less sophisticated measures than 3DMD.

For example, a team at Baylor College of Medicine in Houston, Texas, reported at the 2011 International Meeting for Autism Research in San Diego that severe autism symptoms predict the presence of dysmorphic features — albeit those not discernible to the naked eye. “The vast majority of cases [in that study] show very subtle facial differences,” says Robin Kochel, assistant professor of psychology at the Baylor College of Medicine.

The results of the new study jibe with what she sees everyday in the Autism Center at Texas Children’s Hospital, Kochel says. “Those who have more dysmorphology tend to have more problems and be more severely affected.”

References:

1: Aldridge K. et al. Mol. Autism Epub before print (2011) PubMed

2: Gannon W.T. et al. J. Dev. Behav. Pediatr. 32, 600-604 (2011) PubMed

3: Martinez-Abadias N. et al. Dev. Dyn. 239, 3058-3071 (2010) PubMed

#autism #aspergers #asd

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runwaysng · 1 year

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3 Unique Concepts That Will Sure Improve Your Small Business Mindset

DON'T LIMIT YOURSELF. MANY PEOPLE LIMIT THEMSELVES TO WHAT THEY THINK THEY CAN DO. YOU CAN GO AS FAR AS YOUR MIND LETS YOU. WHAT YOU BELIEVE, REMEMBER, YOU CAN ACHIEVE. Mary Kay Ash A small business mindset helps you feel like you're a part of something bigger than yourself, something special. You do the work, and you feel like the work you do has a purpose and meaning. Every great undertaking begins with a cognitive mindset. It is the wellspring of all successful entrepreneurial endeavours. Without the right mindset, you have little chance of enjoying a breakthrough as a small business owner. By having a good mindset, your business will thrive. This mindset comprises of three key concepts: purpose, people, and products and services. These three key concepts are foundational to how a business operates. So, learning how to manage these concepts and build out this unique small business mindset is essential. This blog post will look at three unique concepts that will surely improve your small business mindset.

WHAT IS A BUSINESS MINDSET?

You must have heard the adage, "As a man thinketh in his heart, so he is." The statement stipulates that your mindset about everything (life, business, dreams, goals, vision, thoughts, etc.) is exactly who you are. Your mindset is the inner eye that sees beyond the physical. A business mindset simply means a way of thinking that enables you to uncover and see problems as opportunities, and then turn those opportunities into a business.

THE CONCEPTS OF SMALL BUSINESS MINDSET

1. Purpose: What's Your Mission? Every business has a reason for its creation. This is the "why" of plunging undefiled efforts into creating a quorum where problems pertaining to human lives are solved. Failure to define and practically understand the purpose of creating your small business is a better way to predict its demise. For instance, Nike's mission is "to bring inspiration and innovation to every athlete in the world." They choose to classify everyone as an athlete, thereby widening their market and aiming to bring inspiration to their target customers who lace up a new shoe or don a new pair of shorts. This business mindset helps to articulate exactly what they do. What's the mission statement of your small business? A mission statement is an actionable declaration of an organization's purpose to its audience. In the case of a small business, a mission statement details the function a company serves for its customers. Your small business' mission is to provide exceptional products and services to your customers that exceed their expectations while providing a rewarding and engaging work environment for your employees too. You are required to be a leader in your industry, leveraging your expertise and innovation to create solutions that add value to your customers and the local community. Ensure that your commitment to ethical business practices and positive impact on the lives of your customers, employees, and community is unwavering. In other words, try as much as possible to know the reason or reasons why you exist. This will help your target stakeholders (e.g., customers, employees, etc.) to know what your small business purpose is so that they can judge if there is a values alignment. 2. People: Who Are You Trying To Serve? Every business is meant to cater to the insatiable needs of a heterogeneous mix of customers in any locality. The main point here is for you to develop a small business mindset that centres on people. You need to cultivate a genuine interest in people. Why? Because your products and services will involve other people, whether you’re managing an entire team, catering to a single customer, or nurturing a growing audience. It is crucial to identify the customers for your products and services. Yes, it is difficult to win new prospects to your small business in a local community. Yet, you can try various methods, at intervals, to understand your target customers or clients. Do a thorough research to ascertain; who your target customers are, what their needs are, and where they are can be found. Through a consistence and deliberate research you will sure improve your small business mindset. Remember that trying to impress everyone means living a chaotic life. Ensure that you are creating something of value to people, not robots. You should read: SMALL BUSINESS: BEST 3 QUESTIONS TO KNOW YOUR TARGET CUSTOMERS 3. Products and Services: What Are Your Offerings? There seem to be two approaches to starting a successful business in any local environment. These are; scratching your own itch, and creating something of value for someone else. The golden rule of your small business is to make something people want. Simple as it may seem, you would not want to offer something that nobody wants to buy or is willing to pay for. When you create value, it helps boost your small business brand in your local community and draw more attention to you. Moreover, your business mindset should focus more on solving a real problem and tirelessly serving a group of people you cared about. The purpose of starting your small business is not to offer products or services that solve your customers' problem, not solely to make money. Lest, the profits comes when you create value that your target customers can pay for. You can check out: HOW TO CREATE VALUE FOR CUSTOMERS WITH TWO HIGH CONVERTING STRATEGIES

CONCLUSION

It's not always easy to stay motivated and focused a small business owner. There are many factors that will frighten you in your locality. It's definitely not easy to stay motivated and focused when you have a million things to do, and your brain can't keep up. One of the best approach is for you to first know your purpose. Also, build networking channel to leverage on other people. You've got to surround yourself with trusted and loving people who will inspire you every day. Moreso, create products and services that are worthwhile, don't just sell something because it's profitable. Read the full article

#Businessgrowth #Inspiration #Localbusiness #Localentrepreneurs #Smallbusiness #Smallbusinessmindset #SmallBusinessTips

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selectivechaos · 1 year

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SM as a phobia

🌹 not a conscious choice:

“Omdal and Galloway (2008) describe SM as a specific phobia of expressive speech. They argue that SM fulfils the criteria for specific phobia in DSM IV (American Psychiatric Association 1994).

According to DSM-5, in contrast with SAD where the individual is fearful or anxious about the possibility of being negatively judged, phobias are not associated with a specific cognitive ideation. Most sufferers of SM do not understand why they do not talk. This inability to explain a reaction over which the individual has no control is consistent with the lack of cognitive ideation that characterises phobias. In Roe’s (2011) study, the most common response to telling others about having SM was, ‘I want to talk but can’t and don’t know why. It’s not a conscious choice’. Alison reflects, ‘It’s not being able to explain why you don’t talk... you don’t fully understand it yourself’ (Sutton and Forrester 2016).” pg 12. so many people have asked me why i don’t talk, and i always felt stupid for not knowing why.

🌹origins of phobias:

“Ollendick et al. (2002) described phobia pathways as being multi-determined with genetic, temperamental and environmental factors (e.g. parental psychopathology, parenting practices and individual conditioning histories) influencing the development and maintenance of childhood phobias. This mirrors the developmental psychopathology framework for SM proposed by Viana et al. (2009) and Johnson and Wintgen’s (2016) ‘Factors contributing to the development of SM’. Johnson (in press) argues that only by viewing SM as a phobia itself can the development and course of SM be explained within such a heterogeneous population.”pg 13.

this argues that conceptualising sm as a phobia can help explain the causes of sm better because sm affects such a diverse range of people that it’s hard to find a commonality. so it’s easier to understand sm as something that originates within the individual as a phobia in itself, rather than look for shared external factors.

🌹similarities between sm and phobias

“This is further borne out by the response of SM and specific phobias to intervention. Firstly, both conditions respond negatively to pressure and avoidance which Johnson and Wintgens (2015, 2016) describe as ‘maintaining factors’. It is well established that a phobic individual must be allowed to face their fear at their own pace. Pressure to do so before the individual feels ready will trigger the fight, flight, freeze response.” pg 13

they then go on to argue along behaviourist lines of negative reinforcement and exposure therapy. but i still think viewing sm as a phobia is intrinsically helpful without recourse to this approach. 🌹🌹

source: ‘Chapter 10: Selective mutism’ by Gino Hipolito and Maggie Johnson. pp 12-13

#selective mutism #situational mutism #phobias #speech phobia #mentalheathawareness #mental health awareness #actually mentally ill #chaos-exhausted

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art-of-mathematics · 2 years

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Yesterday I had an ADHD assessment- yes, on a saturday.

The psychotherapist was very intelligent and empathetic, I can tell. And I showed her the list of all the torture of paradox working meds i had to go through in the recent 8 years, the list of hospital stays, which most of them were traumatic..

As she said she had never seen something like me before. During the talk I spammed her with all sort of recursive thought loopholes and whatever.. I showed her the IQ test from 2014 I had to take - extremely heterogeneous, very poor working memory, and slow cognitive tempo, but logical and verbal reasoning was merely high.

Back then, the guy who tested me was gifted himself and thought my WM and cognitive speed were only so bad due to the neuroleptics... I wish it were true... but the neuroleptics fucked my brain additionally, dopamine antagonists were torture, it is documented...

But, she literally said: There are no diagnostic tools currently available to test anything about me - she had known many people with adhd and giftedness. But, somehow she was impressed by the polymathy of all different sorts of human disciplines, which I all embody in myself.

She said it is obvious but not verifyable by current standards. She aggreed that I am a statistical anomaly, and told me I can only get real help by finding a place in my field(s) of focus/interest and that working on my theses might be the only way to really help me outta that situation. Yet, she also saw the difficulty, as I need proper focus and the accompanied mental stability for that.

But she said, with my history, my excellent mechanisms to function (and literally optimizing of my perception and thinking) and especially with all that went wrong in my medical history - that I can only escape that trap of no-help by stating it's all wrong by proofing my work is true - and also finding my place in the acadmic world.

My mom who was with me was in tears, as, once again, we were left without help - yet, and I am thankful for her honest feedback and her strong (helpful and supportive) opinion about my case,... that is the harsh truth of the current stand of research.

But the occurances that have led me in that awful situation can also help in leading me out of it.

For instance:

I know that many of my mechanisms to cope are highly effective and can even help me release the dopamine in my brain by itself - using certain creative learning methods I am using as kind of biofeedback and literal reward system, for instance.

The results and accompanied theoretical analysis of my mechanisms to function in turn can help improving/optimizing these methods. (Making the feedback a feedback itself.)

It is odd, because since I was a kid I KNEW that once I understand how my perception and memory, cognition work, my "depression" will improve. Since my depressive symptoms came out to be a side-effect of untreated and decompensated ADHD, and overall poorly adjusted/ very turbulent parameters in the algorithmics of my perception and memory processing, and that I could finally understand very much of the underlying mathematical patterns in these non-linear causal nets, I could finally start to optimize it - in concrete.

Since few weeks it becomes clear, and I could start to apply all my methods - and especially, optimize them to become more efficient and functional.

It has been almost three weeks since I could leave the last trauma place. And somehow, my mind can unravel its full potential now. In the last 9 months I started to free myself from the claws of my main abuser and from medical trauma. And especially: I have done that all by myself.

That the psychotherapist with whom we had the appointment of the ADHD assessment yesterday - Despite no concrete ourtcome - her opinion was worth more than anything to me - as she understood the dilemma, she understood me - and she knows that all the things that were said before about me - were sadly not true.

I never intended to be a statistical anomaly. Yet, my psychotherapist in my home town said he has never seen something like me before, just as the psychotherapist from yesterday, and I know like many psychiatrists I encounter tell me the same. Sadly all that was stamped as exaggerated, turns out to be true... as i unravel my spirit now, and can finally start to live as who I am...

This life is the most interesting twist I never saw coming...

I often ironically said my unconventional intelligence cannot be tested. She literally said it. But it's not because it might be incredibly over-the-top... but too unconventional...

As when my thoughts and thinking are observed they change. It is literally that way. As when I myself detect my own thoughts I also alter them. It's due to the chaotic processes in my non-linear perception.. Like my mind is normally in a quantum-mechanically entangled state...

And that is exactly what I concretely research and study in my interdisciplinary research - and to validate my statements, and alter falsified statements - segmentation of concepts - translation of concepts into a "language" of information complexes - turning them into a mathematical formulation and inserting them into my recursive algorithm, one of which primary elements is Bayesian Inference....

It is all like real mind-fuck. But it is impressive how all these complex pieces fit together, despite their highly dynamical nature...

I guess, chaos is really the most efficient form of order, as it is a literal process of self-organization and re-ordering.

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bloodredx · 1 year

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Canticle 1

Everything that ever existed has always existed. That much is given to all. Before the senses could grant capacity to witness and behold the grass beneath toes, cold water on the tongue, or even the singe of a burn, there was nothing. Not even Time flowed. Void, bare, cold and brief, hot and infinite claimed hold to every singular understanding of space. All energies, elements, any particular item that ever existed or would exist in one form or another was caught into webs of singularities. Masses of energy relegated to each type of its own. Like sitting still, never to be touched or changed by another. All was as it remained. And it stayed stable. No measurable structure could define this, but it existed.

So existed in this place, the world before worlds, The First One. The First God to ever open their eyes to the universe in any form. This being, had the notion to leave all at rest, alone, to continue the stability of these energies. Something inside the command was found to be sacred, and for some stretch, they obliged. But might it been equivalent to mortal seconds, years, or eons, the exact nature is lost to the depths of only the First One’s understanding of the event. The First One spent their time drifting betwixt these nodes, all the energy and matter, watching, waiting. But there was nothing. Nothing at all. Stagnation and Silence ruled. The First One grew tired of that.

Yes, The First One in their enigmatic nature found the whole situation to be cantankerous at best. Staring, watching, eternal was much below the capacities of the deity, falling to its own sentiments on the subject. If regret was ever a thought, it is below the mortal understanding, but The First One made the choice that affected all the universe and existence. The method is spoken often, though the meaning of its action is reserved for the gods alone. In a burst of inspiration, or perhaps frustration, The First One parted their lips, and Sang. The first notes, loose and weak, incredibly simple. The same elegance of a child’s first strokes against a violin or notes on a flute, but it was enough. Power was found within such meager sounds, spreading across the void and shaking the fabrics of all to the fibers.

The First One, in shock of this sudden outburst, quickly shut their lips, the sudden timidity that children exhibit masterfully. Finally understanding what could be, it was not long before The First One realized exactly what their purpose should be. Or at the very least, determined that this meaning was more fluid than their initial appreciation of the subject had initially possessed. The Silence behind was not at all what it initially understood, no, in fact a low, filling sound with the same potency and richness as itself. The First One flitted between all nodes, listening, inspecting, seeking a true sense of what exactly should be done with each energy, each element, each minimal and maximal power. What we know to be Resonance echoed through the body of this being, and so The First One understood itself, cognition of self inspiring the recognition of great wings, of heterogeneous eyes, of a name.

Adamsa Narcissta Norinteen Frisay Priasi declared its own name, unfurling their form to completion, and parting lips to become the first Verse of the Song. The notes hurling through the spheres and nodes, knocking them aside in such cataclysmic force that the energies recoiled at first, their own Notes crying out in discordant screams, at brinks of collapse and conflict. Each one rallying against a brother for dominance, not understanding the exact strengths each one carried, for the energies had never perceived another but itself. This strangeness, the source of all, began breaking apart from these first masses, settling out to create new things. Elements mixed and blended, and The First One watched, fascinated. Such glory had never been beheld at all. All due to a few halfhearted Notes, what was the power inside the Song they had now heard? What had it done in destroying the calm that held the Abyss for so long?

#nanowrimo #nanowrimo 2022 #writers on tumblr #Bloodredx writes #Adamsa Priasi #the first one #the first god #cosmology #gods #goddesses #myth #legend #religion #texts #tomes #creation myth #The Song

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starry-fantasies · 1 year

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Very interested to see ur takes! Psychology is incredibly interesting to me, and character analysis is like. The poor man's/"as much as I feel for people therapizing someone is incredibly hard and sensitive and even frustrating bc of the cyclical nature of belief and I know this because *I'm* in therapy" person's case study. I've been through the hospitalization circuits and talk with friends in study, and one thing I've always thought about and have seen contested re: the dsm is the heterogeneity of diagnostic criteria and the role of trauma assessment, as well as diagnosis occasionally getting in the way of recognition of individual's feelings and issues-- all very complicated bc it's fundamentally chemicals changing how you literally THINK affected by externalities you can't control (tired of being put in situations). I've always always loved Cloud since i got into ff7, and his journey can very much be viewed as a story of healing and support through his issues even as he makes terrible choices while in Brain Soupland, and from experience, the parts of healing you can control is a very long process of what's practically "get over urself," as crude and ill targeted those words are, because you're a just a person. This is incomprehensible im sorry basically neurodivergents have varying needs and diagnosis of issues is a step to learning to manage and accept as well as provide a base of medicational crutches but that won't change that people need to be helped with and told different things to start walking. Also internalizing "you're just some guy" and "ppl will be how they are" unironically made my selfimage better

Sorry that it's taken me a while to get back to you! My first reaction was "holy wall of text" so I needed a hot sec to process it, no fault on you.

I completely get what you mean about armchair experts having a hard time navigating the psychiatric world. Diagnosis is already a sticky realm in that you can choose to see it as a constricting web of labels that fails to capture the true breadth of pathopsychological experiences, or as a well-intended effort to categorize human neurodiversity to determine the best possible accommodations and treatments. I believe neurodivergent people already tend to have strong opinions about their personal experience in therapy, which can certainly color the way they choose to see psychologists and psychiatrists. That's completely understandable given that unfortunately some professionals do suck, or you just can't find the right meds for you. Either way, this doesn't mean neurodivergent folks can't become mental health professionals! Pulling from cognitive behavioral therapy, I do think you have a choice in how you make sense of both the clinical world and your own experience with it. Plus, from my personal experience, neurodivergent clinicians tend to vibe more with their clients!

To help you rephrase, I think that when you say that healing is a "get over yourself" process, you mean that healing can't take place if the person isn't willing and ready to start the change process. Which is true, buy-in makes all the difference in therapy. If you want to help yourself, you're more likely to see the change you want. But if you're stubborn about it and insistent that it won't work, you're setting yourself up for a self-fulfilling prophecy. You will subtly sabotage your own growth, even if you don't realize it. I don't think Cloud was ready for help until he was brought to his lowest point, unfortunately. But, I want to emphasize that one of the most important parts of his healing journey is the support of his friends. They were there to stubbornly keep believing in him when he no longer believed in himself. And even if you think you have no friends or family to support you, your therapist is there to unconditionally support you and contain your anxieties and fears about your own circumstances. That's to say, your therapist should be a nonjudgmental presence you can feel comfortable unloading on.

Many therapy modalities work under a weird mix of "I need help" and "I have the power to change things." It can be messy and hard to navigate, and it's definitely no miracle treatment. Hell, as someone who delivers therapy regularly, I have a hard time figuring out exactly how to get the ball rolling sometimes too. Therapy gives you the space for change, but only once you're ready for it. If you go in with the mindset that it's bs, that it's just "talking about feelings" to a guy with a notebook, then that's pretty much all it will ever be to you. I hope this makes sense, and I hope you see the connection to your own personal experience. Thanks for the ask!

#anon ask #therapy #diagnosis

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drpriya · 7 days

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Gene therapy holds potential for treating a variety of brain conditions, particularly those with a genetic basis or where specific genes contribute to the disease process.

Some brain conditions that may benefit from gene therapy include:

Neurodegenerative Disorders: Diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis (ALS) are characterized by progressive degeneration of neurons. Gene therapy approaches aim to either slow down the progression of these diseases or replace damaged cells with healthy ones.

Monogenic Disorders: These are disorders caused by mutations in a single gene. Examples include Tay-Sachs disease, Rett syndrome, and various forms of hereditary ataxia. Gene therapy could potentially correct the underlying genetic defect or provide a functional copy of the faulty gene.

Epilepsy: Certain forms of epilepsy have a genetic component. Gene therapy may target specific genes or pathways involved in seizure activity to reduce the frequency and severity of seizures.

Brain Tumors: Glioblastoma and other types of brain tumors often have genetic abnormalities that drive their growth. Gene therapy approaches can target these abnormalities, either by directly killing cancer cells or by enhancing the body's immune response against the tumor.

Neurodevelopmental Disorders: Conditions such as autism spectrum disorder and intellectual disabilities may have genetic components. Gene therapy strategies could potentially modulate gene expression or correct genetic defects to improve cognitive function and behavioral outcomes.

Mood Disorders: While the genetic basis of mood disorders like depression and bipolar disorder is complex and multifactorial, gene therapy approaches may target specific neurotransmitter systems or signaling pathways implicated in these conditions.

Inherited Metabolic Disorders: Disorders such as phenylketonuria (PKU), mucopolysaccharidoses, and lysosomal storage disorders can lead to neurological complications. Gene therapy may offer a way to correct the underlying metabolic defect and prevent or ameliorate neurological symptoms.

Neurodevelopmental Disorders: Genetic abnormalities, such as Fragile X syndrome, can lead to neurodevelopmental disorders. Gene therapy aims to correct or compensate for these abnormalities to improve cognitive and behavioral function.

The effectiveness of novel therapies for brain disorders can vary widely depending on several factors, including the specific disorder being treated, the stage of development of the therapy, the complexity of the underlying biology, and individual variability among patients.

Here's a breakdown of some factors influencing effectiveness:

Targeted Approach: Novel therapies that target the underlying mechanisms of a brain disorder tend to be more effective. For example, therapies that directly modulate dysfunctional neural circuits or correct genetic abnormalities associated with a disorder have the potential to produce significant therapeutic benefits.

Stage of Development: Many novel therapies are still in the early stages of development, undergoing preclinical and early clinical trials to assess safety and efficacy. As these therapies progress through the development pipeline and accumulate more clinical evidence, their effectiveness may become more apparent.

Patient Heterogeneity: Brain disorders are often heterogeneous, meaning they can manifest differently from one individual to another. Novel therapies may be more effective for certain subtypes of a disorder or in patients with specific genetic or biomarker profiles. Personalized medicine approaches aim to tailor treatments to individual patients to maximize effectiveness.

Delivery Challenges: Some novel therapies, such as gene therapy or targeted drug delivery, face challenges related to delivering therapeutic agents across the blood-brain barrier or targeting specific regions of the brain. Overcoming these delivery barriers is crucial for ensuring the effectiveness of these therapies.

Long-Term Outcomes: Assessing the long-term effectiveness of novel therapies for brain disorders is essential, as some treatments may produce initial benefits but lose efficacy over time or lead to unintended side effects. Longitudinal studies are needed to evaluate the durability of treatment effects and monitor for potential adverse effects.

Combination Therapies: In many cases, the most effective approach to treating brain disorders may involve combining novel therapies with existing treatments or other complementary interventions. Combination therapies can target multiple aspects of the disease process and improve overall treatment outcomes.

Overall, while novel therapies hold promise for improving the treatment of brain disorders, rigorous scientific research and clinical trials are needed to evaluate their effectiveness, establish safety profiles, and identify optimal treatment strategies.

Get the best treatments for various diseases and full body health checkup at the best hospitals in India.

#health #surgery #brain tumors #brain health #brain injury #combination therapy #parkinson's disease #epilepsy #anxiety

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azeez-unv · 12 days

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தமிழில்

BENEFITS OF USING TECHNOLOGY IN EDUCATION

The use of technology in a heterogeneous classroom is to meet individual differences among the students.

Technology should supplement, not replace, an educator.

To Engage students and motivate them to learn the subject in addition to learning how to use technological trends. Tiny dots are now-a-days using technology faster than us.

Upload all learning materials into one digital spot. We can reuse the resources and develop it further.

Technological process does not mean that, such as building a robot or coding. It should be tied to the curriculum, and students should explain their learning.

Integrating technology should also be focused on trial and error and critical thinking as a life skill.

Using technology in the classroom doesn’t have to be perfect. Explore together and let learners step up as experts. Therefore technically technology is getting updated everyday.

BENEFITS

🚥 Faster access to information

🚥Wider variety of learning materials

Increases the scope for distance learning

🚥Eases teaching methods

🚥Improves learners’ communication skills in schools

🚥Makes studying enjoyable

🚥Helps learners to acquire new skills and knowledge

🚥Keeps students updated with the latest technological advancements

🚥Allows students to enhance their mental wellbeing

🚥Makes teaching easier and productive

🚥Helps teachers to track students’ performance and progress

🚥Limits external distractions as much as possible

🚥Improves collaboration between students and teachers

🚥Personalized learning experiences

🚥Improvement in students’ productivity

🚥Gamification that motivates students

🚥Immersive learning experiences

🚥Relieves the stress of parents and teachers

🚥Improves Sustainable learning

🚥Prepares for the digital future

🚥Helps students to learn on their own pace

🚥Gives varied practical experiences and more informations to the students

🚥Helps teachers to have additional teaching tools

FOR STUDENTS:

🚥Connects them with teachers and increases communication.

🚥Enhances group interactions or interaction with other students.

🚥Provides students with access to a vast pool of information.

🚥Helps the students to connect to the outside world.

🚥Prepares students for the workforce.

🚥Engages collaboration with teachers and educational institutes.

🚥Teaches punctuality and responsibility.

🚥Adds a fun factor and sparks interest in learning.

2. FOR TEACHERS

🚥Teach in an enriched learning environment where they can attend to students separately.

🚥Engage the students physically and virtually through AR/VR technologies and multimedia content respectively.

🚥Help students develop practical learning skills by infusing immersive and cognitive exercises in the class.

🚥Provide instant resources to students, which helped them enhance the performance of academic papers.

🚥Grab the interests of students and ensure higher retention.

🚥Meet the unique requirements of students with special abilities with the help of personalized learning tools.

3. FOR PARENTS

🚥Parents could set expectations for their students and track their children’s activities.

🚥They could use technology to help their kids face struggles in education and overcome them. The finest example is the use of a digital homework planner, which works as an attention coach for students with attention deficiency.

🚥Parents could get help from available online resources and educational tools to help their children in completing a task.

🚥They can access educational videos and recorded class lectures to understand the learning experience of their kids and support them.

🚥Parents do not need to continuously keep an eye on their kids to help them focus on their studies and can relax or enjoy their own time.

4. IN CLASSROOM

🚥The technology resulted in immersive and engaging learning with the use of videos, educational TV apps, web resources, and projectors.

🚥Improved collaboration between teachers and students which helps in group activities.

🚥Enabled the schools to engage in practical exercises that improved the cognitive skills and problem-solving techniques of students.

🚥Helped schools understand the educational requirements of different students and incorporate strategies and curriculums accordingly.

🚥Enabled educational institutions to engage in seamless planning, execution, and evaluation of different learning methods.

கல்வியில் தொழில்நுட்பத்தைப் பயன்படுத்துவதன் நன்ம��கள்

ஒரு பன்முக வகுப்பறையில் தொழில்நுட்பத்தைப் பயன்படுத்துவது மாணவர்களிடையே தனிப்பட்ட வேறுபாடுகளைச் சந்திப்பதாகும்.

தொழில்நுட்பம் ஒரு கல்வியாளருக்குப் துணையாக இருக்க வேண்டும்.

தொழில்நுட்பப் போக்குகளை எவ்வாறு பயன்படுத்துவது என்பதைக் கற்றுக்கொள்வதோடு, மாணவர்களை ஈடுபடுத்தவும், பாடத்தைக் கற்க அவர்களை ஊக்குவிக்கவும். சின்னஞ்சிறு புள்ளிகள் இன்று நம்மை விட வேகமாக தொழில்நுட்பத்தைப் பயன்படுத்துகின்றன.

அனைத்து கற்றல் பொருட்களையும் ஒரே டிஜிட்டல் இடத்தில் பதிவேற்றவும். நாம் வளங்களை மீண்டும் பயன்படுத்தி அதை மேலும் மேம்படுத்தலாம்.

தொழில்நுட்ப செயல்முறை என்பது ரோபோவை உருவாக்குவது அல்லது குறியீட்டு முறை போன்றவற்றைக் குறிக்காது. இது பாடத்திட்டத்துடன் இணைக்கப்பட வேண்டும், மேலும் மாணவர்கள் தங்கள் கற்றலை விளக்க வேண்டும்.

தொழில்நுட்பத்தை ஒருங்கிணைப்பது சோதனை மற்றும் பிழை மற்றும் விமர்சன சிந்தனை ஆகியவற்றில் கவனம் செலுத்த வேண்டும்.

வகுப்பறையில் தொழில்நுட்பத்தைப் பயன்படுத்துவது சரியானதாக இருக்க வேண்டியதில்லை. ஒன்றாக ஆராய்ந்து, கற்றவர்களை நிபுணர்களாக முன்னேற அனுமதிக்கவும். எனவே, தொழில்நுட்பம் நாளுக்கு நாள் மேம்படுத்தப்பட்டு வருகிறது.

நன்மைகள்

🚥 தகவல்களுக்கு விரைவான அணுகல்

🚥பல்வேறு வகையான கற்றல் பொருட்கள்

🚥தொலைதூரக் கல்விக்கான வாய்ப்பை அதிகரிக்கிறது

🚥கற்பித்தல் முறைகளை எளிதாக்குகிறது

🚥பள்ளிகளில் கற்பவர்களின் தகவல் தொடர்பு திறனை மேம்படுத்துகிறது

🚥படிப்பை சுவாரஸ்யமாக்குகிறது

🚥புதிய திறன்களையும் அறிவையும் பெற கற்பவர்களுக்கு உதவுகிறது

🚥சமீபத்திய தொழில்நுட்ப முன்னேற்றங்களுடன் மாணவர்களை மேம்படுத்துகிறது

🚥மாணவர்கள் மனநலத்தை மேம்படுத்த அனுமதிக்கிறது

🚥 கற்பித்தலை எளிதாக்குகிறது மற்றும் பலனளிக்கிறது

🚥மாணவர்களின் செயல்திறன் மற்றும் முன்னேற்றத்தைக் கண்காணிக்க ஆசிரியர்களுக்கு உதவுகிறது

🚥 முடிந்தவரை வெளிப்புற கவனச்சிதறல்களை கட்டுப்படுத்துகிறது

🚥மாணவர்கள் மற்றும் ஆசிரியர்களிடையே ஒத்துழைப்பை மேம்படுத்துகிறது

🚥தனிப்பயனாக்கப்பட்ட கற்றல் அனுபவங்கள்

🚥மாணவர்களின் உற்பத்தித்திறனில் முன்னேற்றம்

🚥மாணவர்களை ஊக்குவிக்கும் கேமிஃபிகேஷன்

🚥மிகுந்த கற்றல் அனுபவங்கள்

🚥பெற்றோர் மற்றும் ஆசிரியர்களின் மன அழுத்தத்தைப் போக்குகிறது

🚥நிலையான கற்றலை மேம்படுத்துகிறது

🚥டிஜிட்டல் எதிர்காலத்திற்குத் தயாராகிறது

🚥மாணவர்கள் தங்கள் சொந்த வேகத்தில் கற்றுக்கொள்ள உதவுகிறது

🚥மாணவர்களுக்கு பல்வேறு நடைமுறை அனுபவங்களையும் மேலும் தகவல்களையும் வழங்குகிறது

🚥ஆசிரியர்களுக்கு கூடுதல் கற்பித்தல் கருவிகள் இருக்க உதவுகிறது

மாணவர்களுக்கான:

🚥அவர்களை ஆசிரியர்களுடன் இணைத்து, தொடர்பை அதிகரிக்கிறது.

🚥குழு தொடர்புகளை அல்லது மற்ற மாணவர்களுடனான தொடர்புகளை மேம்படுத்துகிறது.

🚥மாணவர்களுக்கு பரந்த அளவிலான தகவல்களின் அணுகலை வழங்குகிறது.

🚥மாணவர்கள் வெளி உலகத்துடன் தொடர்பு கொள்ள உதவுகிறது.

🚥மாணவர்களை பணிக்கு தயார்படுத்துகிறது.

🚥ஆசிரியர்கள் மற்றும் கல்வி நிறுவனங்களுடன் ஒத்துழைப்பில் ஈடுபடுகிறது.

🚥நேரம் கடைப்பிடிப்பதையும் பொறுப்பையும் கற்றுக்கொடுக்கிறது.

🚥ஒரு வேடிக்கையான காரணியைச் சேர்க்கிறது மற்றும் கற்றலில் ஆர்வத்தைத் தூண்டுகிறது.

2. ஆசிரியர்களுக்கு

🚥மாணவர்கள் தனித்தனியாக கலந்துகொள்ளக்கூடிய வளமான கற்றல் சூழலில் கற்பிக்கவும்.

🚥ஏஆர்/விஆர் தொழில்நுட்பங்கள் மற்றும் மல்டிமீடியா உள்ளடக்கம் மூலம் மாணவர்களை உடல் ரீதியாகவும் மெய்நிகராகவும் ஈடுபடுத்துங்கள்.

🚥மாணவர்கள் வகுப்பில் ஆழ்ந்த மற்றும் அறிவாற்றல் பயிற்சிகளை உட்செலுத்துவதன் மூலம் நடைமுறை கற்றல் திறன்களை வளர்க்க உதவுங்கள்.

🚥மாணவர்களுக்கு உடனடி ஆதாரங்களை வழங்குதல், இது கல்வித் தாள்களின் செயல்திறனை மேம்படுத்த உதவியது.

🚥மாணவர்களின் நலன்களைப் பற்றிக் கொண்டு, அதிகத் தக்கவைப்பை உறுதிசெய்யவும்.

🚥தனிப்பயனாக்கப்பட்ட கற்றல் கருவிகளின் உதவியுடன் சிறப்புத் திறன்களைக் கொண்ட மாணவர்களின் தனிப்பட்ட தேவைகளைப் பூர்த்தி செய்யுங்கள்.

3. பெற்றோருக்கு

🚥பெற்றோர்கள் தங்கள் மாணவர்களுக்கான எதிர்பார்ப்புகளை அமைத்து தங்கள் குழந்தைகளின் செயல்பாடுகளைக் கண்காணிக்கலாம்.

🚥தங்கள் குழந்தைகள் கல்வியில் ஏற்படும் போராட்டங்களை எதிர்கொள்ளவும், அவற்றைக் கடக்கவும் தொழில்நுட்பத்தைப் பயன்படுத்தலாம்.

🚥சிறந்த உதாரணம் டிஜிட்டல் ஹோம்வொர்க் பிளானரின் பயன்பாடாகும், இது கவனக்குறைவு உள்ள மாணவர்களுக்கு கவனத்தை ஈர்க்கும் பயிற்சியாளராக செயல்படுகிறது.

🚥ஒரு பணியை முடிப்பதில் தங்கள் குழந்தைகளுக்கு உதவ, கிடைக்கக்கூடிய ஆன்லைன் ஆதாரங்கள் மற்றும் கல்விக் கருவிகள் மூலம் பெற்றோர்கள் உதவி பெறலாம்.

🚥அவர்கள் தங்கள் குழந்தைகளின் கற்றல் அனுபவத்தைப் புரிந்துகொள்ளவும் அவர்களுக்கு ஆதரவளிக்கவும் கல்வி வீடியோக்கள் மற்றும் பதிவுசெய்யப்பட்ட வகுப்பு விரிவுரைகளை அணுகலாம்.

🚥பெற்றோர்கள் தங்களுடைய பிள்ளைகள் படிப்பில் கவனம் செலுத்தவும், ஓய்வெடுக்கவும் அல்லது தங்கள் நேரத்தை அனுபவிக்கவும் அவர்களைத் தொடர்ந்து கண்காணிக்க வேண்டிய அவசியமில்லை.

4. வகுப்பறையில்

🚥இந்தத் தொழில்நுட்பமானது வீடியோக்கள், கல்வி சார்ந்த டிவி ஆப்ஸ், இணைய வளங்கள் மற்றும் ப்ரொஜெக்ட��்கள் ஆகியவற்றின் மூலம் கற்றலை ஆழமாக��் பயன்படுத்தியது.

🚥ஆசிரியர்களுக்கும் மாணவர்களுக்கும் இடையிலான மேம்பட்ட ஒத்துழைப்பு குழு நடவடிக்கைகளுக்கு உதவுகிறது.

🚥மாணவர்களின் அறிவாற்றல் திறன் மற்றும் சிக்கலைத் தீர்க்கும் நுட்பங்களை மேம்படுத்தும் நடைமுறைப் பயிற்சிகளில் ஈடுபட பள்ளிகளுக்கு உதவியது.

🚥பல்வேறு மாணவர்களின் கல்வித் தேவைகளைப் புரிந்துகொண்டு அதற்கேற்ப உத்திகளையும் பாடத்திட்டங்களையும் இணைத்துக்கொள்ள உதவும் பள்ளிகள்.

🚥கல்வி நிறுவனங்கள் தடையற்ற திட்டமிடல், செயல்படுத்துதல் மற்றும் பல்வேறு கற்றல் முறைகளை மதிப்பீடு செய்தல் ஆகியவற்றில் ஈடுபட உதவியது.

0 notes

lcacommunuty · 29 days

Text

Navigating the Landscape of Long COVID Studies: Insights and Progress

In the wake of the COVID-19 pandemic, a new phenomenon has emerged, presenting a significant challenge to healthcare systems worldwide: Long COVID. This condition, characterized by persistent symptoms lasting beyond the acute phase of the illness, has prompted an urgent need for research and understanding. In this blog, we delve into the evolving landscape of Long COVID studies, exploring the insights gained and the progress made in unraveling this complex condition.

Understanding Long COVID: A Multifaceted Challenge

Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), encompasses a wide range of symptoms that persist for weeks or even months after the initial onset of COVID-19. From debilitating fatigue and cognitive impairment to respiratory difficulties and cardiac issues, the manifestations of Long COVID are diverse and often unpredictable. Understanding the underlying mechanisms driving these persistent symptoms is key to developing effective treatments and management strategies.

The Rise of Long COVID Studies: A Response to a Global Crisis

Recognizing the urgent need to address the challenges posed by Long COVID, researchers around the world have mobilized to conduct studies aimed at unraveling its mysteries. These studies encompass a broad spectrum of research areas, including epidemiology, immunology, virology, and clinical medicine. By leveraging diverse methodologies and interdisciplinary approaches, researchers seek to shed light on the risk factors, pathophysiology, and optimal management strategies for Long COVID.

Insights Gained from Long COVID Studies

The findings of Long COVID studies have yielded valuable insights into the nature of this complex condition. Epidemiological studies have provided crucial data on the prevalence and risk factors associated with Long COVID, highlighting the disproportionate impact on certain demographic groups, including older adults, healthcare workers, and individuals with pre-existing health conditions. Immunological studies have revealed dysregulation of the immune system in Long COVID patients, suggesting a potential role for immunomodulatory therapies in treatment. Virological studies have uncovered evidence of persistent viral presence and viral reservoirs in affected individuals, raising questions about the mechanisms underlying ongoing symptoms.

Progress in Long COVID Research: From Diagnosis to Treatment

As Long COVID studies continue to unfold, significant progress has been made in various aspects of research and clinical care. Diagnostic criteria and guidelines have been established to aid in the identification and characterization of Long COVID patients, facilitating early intervention and management. Clinical trials are underway to evaluate the efficacy of potential treatments, including pharmacological therapies, rehabilitation interventions, and supportive care strategies. Collaborative efforts between researchers, healthcare providers, and patient advocacy groups are driving innovation and fostering a deeper understanding of Long COVID across the medical community.

Challenges and Opportunities Ahead

Despite the strides made in Long COVID research, significant challenges remain on the path towards comprehensive understanding and effective management. The heterogeneity of symptoms and clinical presentations presents a formidable obstacle to diagnosis and treatment, requiring a personalized approach tailored to the individual needs of each patient. Longitudinal studies are needed to track the trajectory of Long COVID over time and assess the long-term implications for affected individuals. Moreover, addressing the social, economic, and psychosocial impact of Long COVID is essential to supporting patients and their families throughout their recovery journey.

Conclusion: A Call to Action

As we navigate the evolving landscape of Studies on Long Covid, one thing remains clear: the need for continued collaboration, innovation, and commitment to unraveling the mysteries of this complex condition. By harnessing the collective expertise and resources of the global research community, we can pave the way towards improved diagnosis, treatment, and support for individuals affected by Long COVID. Together, let us rise to the challenge and forge a path towards healing, resilience, and hope in the face of this unprecedented crisis.

#Long Covid Studies #Studies on Long Covid #Apheresis for Long Covid

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compneuropapers · 1 year

Text

Interesting Papers for Week 20, 2023

Working memory capacity estimates moderate value learning for outcome-irrelevant features. Ben-Artzi, I., Luria, R., & Shahar, N. (2022). Scientific Reports, 12, 19677.

Mutual interference in working memory updating: A hierarchical Bayesian model. Chen, Y., Peruggia, M., & Van Zandt, T. (2022). Journal of Mathematical Psychology, 111, 102706.

Perceptual bias contextualized in visually ambiguous stimuli. Esposito, A., Chiarella, S. G., Raffone, A., Nikolaev, A. R., & van Leeuwen, C. (2023). Cognition, 230, 105284.

Active tactile discrimination is coupled with and modulated by the cardiac cycle. Galvez-Pol, A., Virdee, P., Villacampa, J., & Kilner, J. (2022). eLife, 11, e78126.

Prospective and retrospective values integrated in frontal cortex drive predictive choice. Hamaguchi, K., Takahashi-Aoki, H., & Watanabe, D. (2022). Proceedings of the National Academy of Sciences, 119(48), e2206067119.

Testing models of context-dependent outcome encoding in reinforcement learning. Hayes, W. M., & Wedell, D. H. (2023). Cognition, 230, 105280.

Long-term stability of single neuron activity in the motor system. Jensen, K. T., Kadmon Harpaz, N., Dhawale, A. K., Wolff, S. B. E., & Ölveczky, B. P. (2022). Nature Neuroscience, 25(12), 1664–1674.

Hippocampal representations of foraging trajectories depend upon spatial context. Jiang, W.-C., Xu, S., & Dudman, J. T. (2022). Nature Neuroscience, 25(12), 1693–1705.

Strong perceptual consequences of low-level visual predictions: A new illusion. Jovanovic, L., Trichanh, M., Martin, B., & Giersch, A. (2023). Cognition, 230, 105279.

Phase separation of competing memories along the human hippocampal theta rhythm. Kerrén, C., van Bree, S., Griffiths, B. J., & Wimber, M. (2022). eLife, 11, e80633.

Noninvasive stimulation of the ventromedial prefrontal cortex modulates rationality of human decision-making. Kroker, T., Wyczesany, M., Rehbein, M. A., Roesmann, K., Wessing, I., & Junghöfer, M. (2022). Scientific Reports, 12, 20213.

Spatiotemporally heterogeneous coordination of cholinergic and neocortical activity. Lohani, S., Moberly, A. H., Benisty, H., Landa, B., Jing, M., Li, Y., … Cardin, J. A. (2022). Nature Neuroscience, 25(12), 1706–1713.

Dorsal striatum coding for the timely execution of action sequences. Martinez, M. C., Zold, C. L., Coletti, M. A., Murer, M. G., & Belluscio, M. A. (2022). eLife, 11, e74929.

Mesoscale cortex-wide neural dynamics predict self-initiated actions in mice several seconds prior to movement. Mitelut, C., Zhang, Y., Sekino, Y., Boyd, J. D., Bollanos, F., Swindale, N. V, … Murphy, T. H. (2022). eLife, 11, e76506.

Coding of latent variables in sensory, parietal, and frontal cortices during closed-loop virtual navigation. Noel, J.-P., Balzani, E., Avila, E., Lakshminarasimhan, K. J., Bruni, S., Alefantis, P., … Angelaki, D. E. (2022). eLife, 11, e80280.

Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula. Soyman, E., Bruls, R., Ioumpa, K., Müller-Pinzler, L., Gallo, S., Qin, C., … Gazzola, V. (2022). eLife, 11, e75197.

Spatiotemporal properties of glutamate input support direction selectivity in the dendrites of retinal starburst amacrine cells. Srivastava, P., de Rosenroll, G., Matsumoto, A., Michaels, T., Turple, Z., Jain, V., … Awatramani, G. B. (2022). eLife, 11, e81533.

Visual working memory representations bias attention more when they are the target of an action plan. Trentin, C., Slagter, H. A., & Olivers, C. N. L. (2023). Cognition, 230, 105274.

Self-configuring feedback loops for sensorimotor control. Verduzco-Flores, S. O., & De Schutter, E. (2022).eELife, 11, e77216.

#science #Neuroscience #computational neuroscience #Brain science #research #cognition #cognitive science #neurons #neural networks #neurobiology #neural computation #psychophysics #scientific publications

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corporatenews · 1 month

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Analyzing Mucopolysaccharidosis II Clinical Trials: Insights and Perspectives

Introduction

Mucopolysaccharidosis II (MPS II), also known as Hunter syndrome, is a rare genetic disorder characterized by the deficiency of the enzyme iduronate-2-sulfatase (IDS). Mucopolysaccharidosis II Clinical Trials Analysis In this clinical trials analysis, we delve into the landscape of MPS II clinical trials, examining key insights, trends, and advancements in research and treatment options for this debilitating condition.

Understanding Mucopolysaccharidosis II

MPS II is a lysosomal storage disorder caused by mutations in the IDS gene, leading to the accumulation of glycosaminoglycans (GAGs) in various tissues and organs. The progressive accumulation of GAGs results in multisystemic manifestations, including skeletal abnormalities, joint stiffness, organomegaly, cognitive impairment, and cardiorespiratory complications. MPS II primarily affects males, with variable severity and age of onset.

Clinical Trials Landscape

The clinical trials landscape for MPS II encompasses a diverse range of studies aimed at understanding the disease mechanisms, developing novel therapies, and evaluating treatment outcomes. Clinical trials for MPS II include investigational drugs, enzyme replacement therapies (ERT), gene therapies, substrate reduction therapies (SRT), and novel therapeutic approaches targeting disease pathways and symptom management.

Key Insights from Clinical Trials

Efficacy and Safety of Enzyme Replacement Therapy (ERT)

ERT remains a cornerstone of treatment for MPS II, aiming to replace the deficient IDS enzyme and reduce GAG accumulation. Clinical trials evaluating ERT have demonstrated improvements in urinary GAG levels, organomegaly, joint mobility, and quality of life in patients with MPS II. However, challenges remain in addressing the limited efficacy of ERT in treating neurological manifestations of the disease due to poor blood-brain barrier penetration.

Emerging Therapeutic Modalities

Advancements in gene therapy, including adeno-associated virus (AAV) vectors and lentiviral vectors, hold promise for the treatment of MPS II. Clinical trials investigating gene therapies aim to deliver functional IDS genes to target tissues, thereby restoring enzyme activity and reducing disease burden. Substrate reduction therapies targeting GAG synthesis pathways are also under investigation as potential adjunctive treatments for MPS II.

Patient-Centered Outcomes and Quality of Life

Recent clinical trials have focused on assessing patient-centered outcomes and quality of life measures in individuals with MPS II. Patient-reported outcomes, caregiver burden assessments, and neuropsychological evaluations provide valuable insights into the impact of MPS II on daily functioning, social interactions, and emotional well-being. These outcomes inform treatment decisions and contribute to holistic patient care approaches.

Challenges and Future Directions

Despite significant progress in MPS II clinical research, several challenges persist, including the need for early diagnosis, access to therapies, long-term efficacy and safety monitoring, and addressing the heterogeneous nature of the disease. Future directions in MPS II clinical trials include the development of next-generation therapies with improved efficacy, durability, and CNS penetration, as well as the implementation of multidisciplinary care models and patient registries to optimize treatment outcomes and inform clinical practice.

Conclusion

In conclusion, clinical trials play a pivotal role in advancing our understanding of Mucopolysaccharidosis II and developing innovative therapies to improve patient outcomes and quality of life. By leveraging insights from clinical research, collaborating across disciplines, and prioritizing patient-centered care, stakeholders can accelerate progress towards effective treatments and ultimately, a cure for MPS II. Through ongoing clinical trials and translational research efforts, we remain committed to transforming the lives of individuals and families affected by this rare and devastating genetic disorder.

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art-of-mathematics · 2 years

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What field are you in and how do I get there? ( I dont understand shit from your posts but they're the coolest things I've ever read)

Hi their, thanks for coming along my ask box - unfortunately I am not really able to offer a plain answer - as I am currently doing it all in isolation (autodidactic) - working on all that stuff since ten years - and I am also working on writing about my principles of research/learning - most I do is interdisciplinary - I recommend Vijay Balasubramanian's work - polymath in mathematics, theoretical physics, theoretical cognitive science - he researches about statistical inference, quantum field Theory, quantum gravity, string theory and I can't summarize the broad spectrum of his research more clearly now. My work is merely similar/related - yet, it is a mess to explain - Although math, physics and cognitive science might be my main sevtors of focus - my knowledge is 'heterogeneous", say, I lack much of the rigourously studies topics one learns along the formal education path.

Currently I do some merely low-level stuff, basic calculus/analysis so to speak - but the approach of how I understand is... is merely odd. You see how I synthesize multiple perpectives/modes of perception. I find the notation of integral and differential calculus confusing - somehow, my journey into analysis started with fourier transform, superposed waves and multiple parallel thought ramblings - In retrospect, the mathemetics is the actual and concrete form of how I have perceived my own reasoning and perception.

And I understand why people think it might just be psychotic nonsense. Yet, the methods are highly advanced. I try to put them in a comprehensible language/mathematical model/algorithm currently.

To further investigate career options, I think about seeking entry into the academic world through the IT sector - most certainly quantum developer - I want to write assmbler code for non-lineary working quantum computers, so to speak. Good thing: I could apply much of my own research directly and advance/develop them better [especially the non-linear axiomatic system/quantum information flows topics] and say, start research without having a degree - but that might open some options to attend university programs, or get a degree in the future, and especially: I could do what I love, and could finally learn to master my stuff in a way that is functional and applyable in that world - and not just rotting in my filecases...

Yet, my health, being neurodivergent, having no support socially/in health issues/financially, and german buerocracy are really hindering factors in that constellation of situation - especially if they are combined.

Yet I have a rough plan. In the recent weeks I could finally leave a many-year long traumatic situation - one that involved my father keeping my mind tiny - supressing and abusing my neurodivergent self - whatever, I do not want to burden with details nor do I want to be pitied. It gets better and I can finally unravel my potential and start my academic life - tough, in a very odd and statistically unprobable way - but that's it: In some sense I use(d) game theory to free myself from that trap of situation: An almost zero percent probability to have a fullfilling life becomes gradually more probable - as for now, it's me showing initiative and dedicated autodidactism that has secured me a hope to a career in my special interests. (I am sorry for the much bla bla)

Alongside that way I also try to make mathematics more accessible and enjoyable for curios and/or neurodivergent people. As I believe, hope is something people need more than ever. And a new way to see can be exactly that for some people. Especially neurodivergent people have to suffer tremendously under that worldwide defective education system - alongside other systematic deficits including basic human dignity and respect. In some sense, I want to write books, create content and art on mathematics and other inspiring branches, to inspire, to give someone the hope and enthusiasm I wish I would have received as kid, to ignite a flame of wonder and awe - and in some sense, yes, I am becoming sentimental, but honest, somehow, ten years ago, I have received that hope of inspiration on that platform - by fellow (most certainly also neurodivergent) blog owners/content creators. And if I look back, I am extremely thankful for the kindhearted and honest community here, the hilarious puns and posts, the insightful debates, the silly memes, the common appreciation for infodumping on special interests, and the very humane and heart-wearming and welcoming social interaction.

I could link some users here, but I would feel bad if I forgot some - so, in some sense, for whoever is reading that - I am thankful for our encounter!

(Ahh completely lost track of my thoughts...) I really appreciate your appreciation! Yet, I can't really give you info in how you could get iny my field - as I do not know it myself unfortunately. But I let you know once I know more. (I can only recommend Vijay Balasubramanian's work. As he is already in that career path, maybe research about him might be helpful... interestingly he also entered via the CS sector...)

#speronyx

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