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#supplement for brain
nutrilifi · 4 months
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Practical application of nootropics. Effectiveness of use
Nootropics are drugs or nutritional supplements that have a specific effect on higher mental and cognitive functions. The concept of nootropics was first proposed in 1972 with the discovery and description of the properties of piracetam, in particular, its stimulating effect on memory functions. Today there are 18 classes of nootropic compounds, differing in their mechanisms of action – their interaction with receptors of the central nervous system, enzymes and ion channels, growth factors, antioxidant defence system, etc. The clinical efficacy of nootropics is determined by the clinical efficacy of their action.
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Clinical efficacy of nootropics
The mechanism of action of pyrrolidone nootropics is based on the regulation of cholinergic deficiency, enhancement of cholinergic transmission and allosteric regulation of dopamine receptors, due to which their stimulating effect on higher cognitive functions is realised. In addition, compounds of this class contribute to the increase of norepinephrine concentration in brain structures.
Clinical and preclinical studies prove high efficacy of pyrrolidone derivatives in a wide range of neurological and cerebrovascular pathologies accompanied by cognitive disorders.
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azaisya · 1 month
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@just-another-linguist and @melestasflight both requested Fingon which was v exciting. Fingon is one of the characters that really stuck with me the first time I read the Silm, but I’ve never actually drawn him. In my mind this is like a Valinor-era Fingon!
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artheresy · 4 months
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I can’t stay quiet about this, I need to scream it to SOMEBODY ANYBODYYY
Dan Heng and Blade were Dan Feng and Yingxing. “Dh and Bld are Df and Yx!” Nope, their current selves aren’t them, that lacks nuance. “Dh and Bld aren’t Df and Yx!” THAT ALSO LACKS NUANCEE they are still connected and fundamentally shaped by their past identities, they aren’t entirely separate from them while also still being separate in a way. The best way I can describe it is like a venn diagram, there is overlap, but there also are still areas where they don’t.
To expand more, I wanna talk about the way they foil each other a bit in this sense. For Dan Heng, even if he is a botched rebirth, simply a “de-aged Dan Feng” not fully reborn, he is still not Dan Feng. While Dan Feng has made up the basis of his personality and he accepts him as his past, I think we forget that Dan Heng had his own entire childhood after the molting rebirth was completed. One he spent imprisoned by the Ten Lords Commission, and then he was exiled when he was old enough leading to his whole journey until he became apart of the Astral Express crew etc etc. Dan Heng is made up of a basis of Dan Feng + All of his own memories and experiences. While he shares traits with Dan Feng such as personality aspects like his stubbornness, his technique with a spear, and being able to connect with his old items, he also is very much himself with his own outlook and traits shaped by what he’s learned rather than what he has been born with. To treat him as if he is Dan Feng exactly is a disservice to both of their characters and the greater narrative that they apart of. He may still carry the burdens and karma of Dan Feng, but Dan Heng is still making his own future.
Now, Blade. Blade similarly is not Yingxing, not completely. Though he accepts Yingxing’s sin as his own and is intent of repaying the sin of Dan Feng and Yingxing (and getting Dan Heng to repay it too), there still are distinctions between him and Yingxing. In fact, I’d argue there are more things separating them. I could talk for so long again about the layered use of craftsmanship to connect, or rather disconnect, the two identities of Blade and Yingxing, but there’s more than that. “Now, ██ had died. His first — and only — death.” “From this moment on, that body will be the one and only "Blade."” Although Blade was Yingxing, a disconnect exists between them through the death of Yingxing. He awoke with no memories of his past, no even his name, until Jingliu came along, instilled in him her ideologies, made him remember, not only his past sins but the feeling of death so that he might inflict it onto others. As she said, he was reborn and had even given himself a name…
I want to add that the specific ways in which their current identities exist in proximity to their past ones foil each other. As I said, Dan Heng, in part as his sabotaged rebirth, is built upon the foundation of Dan Feng and all of his own experiences and memories. He has the capacity to gain back more memories of Dan Feng as his DH IL character stories outline, and though he is still himself and still moves forward, we see him accept his relation to Dan Feng eventually. Though that past life of his is clouded by fog and mist, he may eventually be able to push away the clouds that block him and understand more, about Dan Feng and in turn about himself. With Blade, it is so heavily emphasized in game from his relic lore to the very sword he uses that his mind is essentially broken, due both in part to the trauma of Jingliu’s “teachings” and the mara that was brought on by those lessons. He can’t fully remember everything about Yingxing, in fact actively remembering such or seeing familiar things is harmful to him. Like his shard sword, he is made of broken pieces, put together in a way that can never erase the cracks, and continuously shattering before being glued together again. His life is shaped by Yingxing’s past, the trauma he has endured is directly caused by his past actions. Unlike Dan Heng, he hasn’t had this whole life to build up and live. Though he’s experienced new things, they don’t shape him and change him in the way that Dan Heng’s built his identity up.
Where Dan Heng basically has supplements to Dan Feng’s identity that make him who he is, Blade is the broken shards and pieces of Yingxing that weren’t lost to the waves, making him who he is. Dan Heng is a next chance, finally free from the Preceptors’ control and of the role that stripped his past selves of their individuality, meanwhile Blade is the husk left behind of Yingxing’s regrets, broken by trauma caused due to Yingxing’s past actions, forever tormented by his past until he inevitably is able to die. If Dan Heng is more than just Dan Feng which is why he is separate but intertwined with him, than Blade is less than Yingxing, in a way that has caused such a severe disconnect that has caused Blade to have his own identity still shaped. And looking at this, not to again bring up my craftsmanship post about Blade, Dan Heng can connect to Dan Feng. He can clear the fog, remembering his memories through dreams even if he can’t fully connect emotionally to him, and he finds sentiment in many of items that once were his, smth not many Vidyadhara actually are capable of doing. To contrast, Blade is forever separated from connecting completely to Yingxing’s identity. His memories will always be fragmented, his own path entirely changed. He can’t connect to Yingxing’s past goals and passions, seen through the distinct decision made in his character stories to talk about how he can no longer use his hands to forge weapons (something that completely defined Yingxing’s life and legacy, tied to his childhood trauma and hatred of the Abundance, something that became his genuine passion), and how none of that mattered to Blade.
All of this, the ways they foil each other and the separation between their past selves and current, just makes me love their dynamic and their lore a lot. Makes me want to cry most days of my life if I’m honest. And it’s part of why I do take issue with the way nuance has completely left this argument, only having two extremes of “Dan Heng is Dan Feng!” Or “Dan Heng isn’t Dan Heng!” Again… Dan Heng WAS Dan Feng, he wouldn’t be Dan Heng without Dan Feng, but he is still himself. That’s part of the tragedy between them. They are still fundamentally defined and shaped by their past selves, similarities able to be spotted if they can be remembered, but they’ve also experienced so much that has changed them, and they can never truly go back to being Dan Feng and Yingxing. It would never be fully the same again.
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hellyeahsickaf · 3 months
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Be careful with adrenal supplements it turns out that shit makes you produce adrenaline and my ass got paranoid that I had mad cow disease (I'm a vegetarian) and I almost threw up realizing a bear could fit through my window if he wanted (I live in a major city)
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official-rugi · 5 days
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I wanted to draw something rly nice of my new guy and also try out some more difficult posing, so Fireman OC does what fireman do XD
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pastafossa · 9 months
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Ok. TRT business and a question, cause I need feedback from readers at this point.
First: the final chapter of the Raven What If fic should be posted this week, I'm about done editing it. The bigger, much more important question: So I have a potential chapter for tomorrow. I've been worrying and fretting over posting it, not because I think it's bad, but because it's short by TRT standards, currently around 2k words, and it both frustrates me and makes me feel weirdly guilty at the thought of dropping what's so much less than my usual. I'm used to being able to write longer chapters, being able to squeeze everything I want into them, and I have a literal outline of this goddamn chapter that has this good stuff in it and I know what needs to be written. I can see it right there. The movie is playing in my head just fine. But the truth of it is, my writing is slow at the moment thanks to post-covid brain fog. I'm checking in with my doctor, I've started taking specific supplements (which I'm hoping to see results from in the next few weeks), I'm clawing my way back bit by bit, but I continue to write slowly, mostly because I either can't focus or I have to stop every few sentences to struggle with a word I can't remember. It's incredibly frustrating. The thing is though, at least I *am* writing, which gives me hope. But this is where you - the readers - come in. Because right now we have two possible paths for updates going forward for a bit. Option 1: Longer gaps between our usual chapters. If we go this road, it'll take longer but as I chip away, I'll eventually have the full planned chapter, which I'd post. This would be a chapter closer to what we've had most weeks for the past oh god like 2 years. At current speed I'd drop it in a few weeks, and then hopefully the next one would come a little faster, until eventually we're back to our usual. So basically, you'd get your big chunks when the updates do come, and the same natural endpoints and arcs as before. Drawback is obviously the time between updates, so you won't be fed as often (though I'd try to find things in my editing folder to clean up and drop, like the Raven fic).
Option 2: Shorter chapters but more regular updates. If we go this road, we'd be back to weekly updates of our adventures with Matt and Jane. There'd just be less than usual for a bit and then, hopefully as I improve, you'll see the word count begin to climb back up. So in this case, you'd be getting a weekly dose of TRT, the usual fluff and angst and action, but the catch is less overall to read (likely individual scenes rather than multiples), and potentially sudden endpoints/more cliffhangers as I 'end' at what was outlined as a scene change.
Which way I go will mostly depend on ya'll tbh. I think I can make either work, since I've managed to start writing a little again and I really, really am hoping the supplements help. But since this'll potentially alter the update schedule we've had for years, I wanted to see which you'd prefer.
So, Option One - longer gaps but long chapters - or Option Two - shorter chapters weekly. Which would you prefer?
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definitelynotshouting · 7 months
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(Hunger au) I'm going into ecology and it's fascinating looking at your au's ecosystem, especially since this doesn't necessarily seem driven by natural selection and instead by just. The universe creating what it needs, with a purpose in mind. That's so different from our world that it's fascinating to think about the implications. Rather than existing to take advantage of and respond to resources and selective pressures, theyre basically creating said resources/pressures. The watchers are having to manually adapt to survive after a bottleneck effect, which to be fair even if there was natural selection they'd probably have to cuz adaptation takes a looong time in species with long reproductive cycles. Do they have a genome? Or are they just being arbiters of mutation themselves (by that i mean theres no genome so theyre changing their species themselves since theres nothing to mutate)? Do offspring inherit traits? What does this mean for natural selection (cuz like. If they survive differently depending on how their traits match up to the environment and selective pressures there is)? With the seekers gone are expected to have a population rebound barring any other selective pressures/fitness independent factors on their population? Their reproductive strategy seemingly aligns with the low pressure they're facing... I read a paper to understand this and it's really cool:
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(From https://www.nature.com/articles/s41598-019-42562-7)
They seem to be an r-selected species and invest a lot in their offspring, but they just naturally have low infant survival rates. This is the sort of species that does not do well in the long run so that adds urgency to their efforts to edit themselves.
All this to say that I'm rotating the concept of an ecological system that has one of ecology's core tenants (evolution) heavily altered/removed. Tis fascinating.
between you and chem anon im going to have a heart attack over sciency people looking at my silly au /lh
I really did want to go like vastly different from how our world works since this is such a video game setting-- it was really fun to noodle about what a universe made out of code instead of DNA would look like!!! and having the universe be quasi-sentient, affected by a form of evolution itself as well (thank you julien gough for the universe evolution theory that i have wholeheartedly adopted into my worldview).... idk its led to some very interesting worldbuilding for sure 😂😂😂
Watchers-- or any entity in this universe, actually-- dont really have a genome like we'd understand it. Instead, theyre made up of code and code blocks, which i guess would sorta mimic that to a certain degree, but its more tipped in favour of computer programming than biology. The whole au sorta just wholesale marries the two together, along with physics and chemistry (i am currently percolating on how crafting works in this au rn and my current idea involves the concept of the crafting table acting somewhat like a catalyst, which. okay dont take that as gospel yet i havent fully cooked on that one) etc etc etc.
But the Watchers did intentionally change their coding to help defend against the Seekers when they were being hunted into extinction!!! Watchers already had a natural affinity for deep coding, so while it took a lot of effort and caused a lot of damage to themselves, they managed to rapidly change their code structure (aka this universe's version of genetic makeup) to get better at, well. Watching. Seeing the Seekers coming far enough in advance to run before they got there became their primary defense against getting voraciously hunted, and by the end of it the Seekers starved out and went extinct bc they'd gotten so adept at avoiding them.
Offspring is interesting because in my mind at their base level (so genetically/code structurally speaking), Watchers are identical clones of each other. They reproduce asexually-- think uhhh mourning geckos and some species of aphids, which reproduce via parthenogenesis. So yes, in a sense they do inherit traits, but its in a direct line from the parent as a genetic copy. Their memory codes and surface code layers are what differentiate themselves from each other
Reading this chart is so interesting.... i'd say you're right in that Watchers would be considered an r-selected species!! I think if they werent like. Essentially made out of tissue paper thats constantly getting damaged and having to be repaired, they would be able to bounce back to the point of population rebound for sure. The problem with that though is there are only about 40 Watchers left-- thats how bad and out of control the situation got. And since they have such a long reproductive cycle, and such a high infant mortality rate, and their experiment with Grian went so wrong, AND the universe formed Listeners to replace them via direct competition (Watchers cant feed from Listener-infected Players!!), they are unfortunately headed right for extinction too.
Hopefully this makes a modicum of sense and isnt just me totally talking out of my ass wkdnjedjkejdke but i hope this answered most of your questions!!! Im really glad you like the direction ive taken this, its a lot of fun to conceptualize a world that works on different rules than our own :]
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spell-fox · 18 days
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the weather is nice, urge to sit outside and read a new VtM dark ages supplement rising
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kagiura-akira · 10 days
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Whether I’m up or down, or wear no crown, Love me the same way you did as yesterday Whether I’m rich or poor, just call me yours Love me the same way you did as yesterday
A kghr beach wedding 💍🏳️‍🌈
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crimsongrimoire · 23 days
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i may not know fuck or shit about hsr but whatever is wrong with boothill is fascinating. also horny robot thoughts
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wiezumbeispiel · 2 years
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[glados voice] oh, you were busy back there—
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trans-axolotl · 10 months
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having a lot of thoughts about eating disorders + how some of us end up developing chronic illnesses directly because of the physical effects of our eating disorders and how Cruel doctors can be about that and just trying to untangle so much shame and blame from that experience rn
#personal#vent#eating disorder tw#disability#idk. i don't quite have the words for this right now but#had another meeting with my doctor where they said yeah its your fault that you are now physically disabled for life#(literally i was chronically ill and physically disabled before i even developed an eating disorder because of CAH and comorbidities but#(they love to ignore that !)#which is like. i do not tie any morality to health and it should just be#a completely neutral statement. that my eating disorder caused other physical complications#they said i'm going to have orthostatic problems the rest of my life.#'since your gastroparesis was caused by your eating disorder that means there is no point in treating it'#which is so funny bc literally every time i see her my dietitan wants me to get a feeding tube! lmfao!!!!#i am actually doing pretty well in recovery in terms of meeting my energy needs through food. but i stopped being able to orally supplement#so my dietitan wants a tube for ARFID nutrient reasons. supplemental nutrition etc etc. and she thinks it will help gastroparesis symptoms#they also think i have osteoporosis and want to test me for that#when i had to use forearm crutches/ wheelchair because of physical ed complications doctors were SO fucking rude even though they were#the ones PRESCRIBING IT!!! like!!! you all are the ones telling me i HAVE to do this!#idk i also have a friend with permanent brain damage. from seizures in the refeeding process#and her doctors are so fucking rude to her all the time.#it makes me so mad
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orcelito · 2 months
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With a combination of medicine, excessive water, and Soup, I am feeling... okay.
Very sleepy. But at least it's not agony to swallow like it was last night. So I'll take it.
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syrasenturi · 2 years
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brainworms
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why do these b12 supplements feel vaguely psychoactive
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magz · 3 months
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We took a cebrinol today too.
Can you tell.
Am also sitting slouched on couch, bc momma cat yenifer said it was her turn on our bed (she don't want to be disturbed)
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