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#neonatal
vyorei · 6 months
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A short video from Al Jazeera on the desperate conditions around childbirth in Gaza right now
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broadlyepi · 3 months
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Respiratory distress in SARS-CoV-2 exposed uninfected neonates followed in the COVID Outcomes in Mother-Infant Pairs (COMP) Study
Top 5 Takeaways
High Rates of Respiratory Distress in Exposed Uninfected Neonates: The study found unusually high rates (17%) of respiratory distress (RD) in SARS-CoV-2 exposed uninfected (SEU) term neonates.
Maternal COVID-19 Vaccination Reduces Neonatal RD: Maternal vaccination against COVID-19 significantly reduced the frequency of neonatal RD, with a 67% decline in the odds of RD in neonates born to vaccinated mothers compared to those born to unvaccinated mothers.
Proteomic Analysis Reveals Inflammatory Response: Proteomic analysis indicated a robust inflammatory response in SEU neonates with RD, involving pathways like ciliary dysregulation and enhanced IgE production.
Demographic and Clinical Factors: The study enrolled 221 pregnant persons with COVID-19 and 227 exposed fetuses. It highlighted the correlation of RD with factors like maternal disease severity, prematurity, and the absence of maternal COVID-19 immunization.
Th2-Skewed Immune Response in SEU Neonates: SEU preterm infants with RD showed a Th2-skewed immune response, indicated by elevated levels of certain cytokines and the inhibition of FC gamma receptors.
Original Article Author and Citation
Olivia M. Man, Tamiris Azamor, Mary Catherine Cambou, Trevon L. Fuller, Tara Kerin, Sophia G. Paiola, Jessica S. Cranston, Thalia Mok, Rashmi Rao, Weiqiang Chen, Jae U. Jung, Viviana Fajardo Martinez, Suan-Sin Foo, Karin Nielsen-Saines
Suggested Citation
https://doi.org/10.1038/s41467-023-44549-5
Summary
The study aimed to understand the impact of prenatal COVID-19 exposure on neonatal respiratory distress (RD). A high incidence of RD was observed in SEU neonates, and maternal vaccination notably reduced this risk. Proteomic analysis suggested a strong inflammatory response in these neonates.
Methods
The research employed a longitudinal cohort study approach, enrolling mothers with confirmed SARS-CoV-2 during pregnancy and their exposed fetuses. Various demographic, clinical, and proteomic analyses were used to understand the complex relationship between maternal COVID-19 parameters and infant RD.
Discussion
The findings highlight the protective role of maternal COVID-19 vaccination in reducing neonatal RD. The study also revealed a Th2-skewed immune response in SEU neonates with RD, suggesting potential long-term implications, including the development of allergic processes and pulmonary fibrosis.
Conclusion
Maternal vaccination against COVID-19 significantly decreases the risk of neonatal RD in SEU infants. The study underscores the importance of maternal vaccination for reducing neonatal morbidity and improving long-term infant health.
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drsonnet · 6 months
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"...medical teams refused to leave the hospitals, staying behind to take care of patients in ICUs and NICUS who could not move without dying. This includes 48 premature babies whose incubators and respirators have since failed."
"... رفضت الفرق الطبية مغادرة المستشفيات، وبقيت هناك لرعاية المرضى في وحدات العناية المركزةICUs ورعاية الخدج NICUs الذين سيتسبب نقلهم بوفاتهم. ويشمل ذلك 48 طفلاً خديجًا تعطلت حاضناتهم وأجهزة التنفس الصناعي منذ ذلك الحين."
@LatuffCartoons #غزة #Gaza #MedTwitter
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doctxrdoctxr · 10 months
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cbirt · 1 year
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Enhancing the Comprehensive Diagnosis of Neonatal Infectious Diseases Through Metagenomic Next-Generation Sequencing
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Scientists from Xi’an Children’s Hospital have shown that metagenomic next-generation sequencing (mNGS) of cell-free DNA (cfDNA) and RNA may help detect trace infections from various bodily fluids and blood samples extracted from newborns. Researchers also performed a local polynomial regression fitting analysis, which revealed that the best time for detecting mNGS was 1 to 3 days following the initiation of antimicrobial medication. The study’s findings emphasize the value of mNGS in detecting causative DNA and RNA infections in infected neonates.
Newborns are frequently susceptible to infections, such as sepsis, meningitis, and pneumonia, which account for millions of infant deaths yearly. Apart from the mortality rates, adverse prognoses may arise in neurodevelopmental problems and long-term disability if timely treatment is not given. Pathogenic microorganisms causing such infections include a diverse group of bacteria, viruses, and fungi. Therefore, timely and valid pathogen identification and appropriate therapeutics are required to enhance prognoses. 
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Oh, Archie! What a beautiful model for these quick neonate sweaters I whipped up in a hurry to keep this baby warm.
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https://www.hippocraticpost.com/australasia/stillborn-and-preterm-statistics-for-covid-19-first-wave/ Interesting research. The research of 52 million births from 26 countries, published in Nature Human Behavior, reported a 3-4 per cent reduction overall in preterm births, averting almost 50,000 preterm pregnancies during the first month of lockdown alone. But the decrease in preterm births was limited to only high-income countries including Australia. The International Perinatal Outcomes in the Pandemic (iPOP) Study, one of the largest such studies of its kind, involved 167 collaborators across 42 countries. Murdoch Children’s Research Institute co-led the project alongside The Children’s Hospital Research Institute of Manitoba, University of Manitoba, The University of Edinburgh and UNSW Sydney. #preemiefamily #preterm #prematurebabiesawareness #neonatolgy #neonatal #prematurity #earlybaby #earlybabies #premature #research #nicuparents #nann #NICU https://www.instagram.com/p/Cpvrxnaqzb2/?igshid=NGJjMDIxMWI=
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dr-scarlette-witch · 8 months
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13.09.2023
Had a busy couple of days. I am currently waiting for my official announcement for my course commencement. Until then I decided to tutor at a nearby coaching institute and I was kept busy, also it helps me pay for my Uworld.
Last Sunday I got a day off and I decided to meet my closest friends from school. We have know each other for over a decade and a half and our lives are so different now, but like every time we meet and hangout it feel like nothing has changed. So had lunch and decided to go beach hopping, while we reached the beach it was too sunny so we decided to wait for sometime, when we noticed this huge black cloud moving towards the beach from the sea. And our dumbasses were like yeah we ll go to the sea when the cloud comes closer because it will be less sunny then🤡. Long story short as soon as it got cloudy we walked towards the sea and the cloud bursted into a heavy 5mins rain and we all got wet👍🏽. Got my car covered in sand and rain water. Anyways had a good time.
Today I have an evening full of free time. Planning to read some neonatology. As I said before, I feel that I have a lot of unclear topics when it comes to neonatology. I am currently reading AIIMS NICU protocols, because I feel the language used is simple and I can cover the book faster and I feel that it will be enough for my first year residency.
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juniperandjustice · 1 year
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Important info about cat moms and babies and their blood types!
From the Tiny Kittens livestream on YT showing the mama kitty having her babies: "Type B blood means Orinda's kittens will be at risk for a fatal condition called Neonatal Isoerythrolysis.  This happens when a type B mom gives birth to type A kittens. Mom passes her anti-A antibodies to the kittens in her colostrum, and those antibodies kill the kittens' red blood cells. Thankfully, we have had a LOT of experience with this and have been able to save 100% of the kittens born in our care who would have died from NI. The protocol required to save them is definitely worth it, but it gets pretty tough when we're working with stressed feral mamas." I didn't know about this.  This seems like important information to share.   https://www.youtube.com/live/SATiOd-YMLY?feature=share
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ahhvernin · 2 years
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Some heavy words:
Periviable
Cannot cry
eyelids fused shut
A heart pulsating through the gelatinous sheen of immature skin. 
Skin should be a barrier between a body and everything outside it, but a periviable baby’s skin lacks the outermost layer .
Just these descriptions are enough to turn on the red flags of "the baby is 'sick' upon arrival it cannot breathe on its own, and most Americans cannot afford this care or the care after discharge".
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alkaridevihospital · 1 month
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Skin Infection in Children: Prevention and Cure
Childhood is a time of exploration and discovery, filled with laughter and play. However, it is also a period when children are more susceptible to various ailments, including skin infections. Skin infections can cause discomfort, distress, and even affect a child’s daily activities. Understanding the causes and implementing prevention measures can help keep these infections at bay, ensuring our…
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vyorei · 6 months
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They're literally pumping oxygen by hand trying to keep these babies alive whilst the hospital is surrounded by the IOF.
Fuel, which is vital to power the incubators and various other machines that keep preemies and other patients alive, is allegedly being permitted into Gaza according to the earlier report I've popped below, but for the UN trucks and not the hospitals
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jamrmed · 2 months
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Multi-Parameter Equipment
Our multi parameter vital signs monitor is a cutting-edge device designed to provide comprehensive health monitoring. With its advanced technology, this equipment is capable of detecting various cardiovascular parameters, ensuring a thorough assessment of an individual's health status.
Types of neonatal multi parameter monitor in Jamr
Our multi-parameter equipment integrates essential vital sign monitoring functions, such as blood pressure measurement, heart rate monitoring, oxygen saturation levels, ECG testing, AFib detection, and atherosclerosis detection. This comprehensive multi-parameter vital signs monitor allows healthcare providers to efficiently monitor multiple aspects of a patient’s health simultaneously, saving valuable time and resources. With accurate and real-time data, healthcare professionals can make informed decisions and deliver comprehensive care to their patients.
Important Parameters of Cardiovascular Health
Identifying potential issues of cardiovascular health is crucial for maintaining a healthy heart. There are several important parameters that healthcare professionals use to assess the risk of cardiovascular disease. These include blood pressure, ECG, SpO2, AFib, and arteriosclerosis.
Blood pressure is a measure of the force of blood against the walls of arteries and is a critical indicator of heart health. SpO2 is a measure of the oxygen saturation level in the blood and is used to assess respiratory function. ECG is a test that records the electrical activity of the heart and can detect abnormalities in heart rhythm. AFib, or atrial fibrillation, is a type of irregular heartbeat that can lead to blood clots and stroke. Arteriosclerosis is a condition in which the arteries become narrow and hardened, which can increase the risk of heart attack and stroke.
By monitoring these parameters, healthcare professionals can identify potential issues with cardiovascular health and develop treatment plans to prevent or manage cardiovascular disease. It is important for individuals to schedule regular check-ups with their healthcare provider to ensure that their heart is healthy and functioning properly.
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drsonnet · 5 months
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10-11-2023 Northern Gaza:
“We had to leave the patients behind. In the ICU of Nasr Children’s Hospital, we had to leave the patients in their beds…We left surrounded by tanks. We couldn’t take any of the patients with us.”
#ICRC committed to transport these NICU babies to another hospital or any safe place upon evacuation of the Hospital. #ICRC left those children there to die in collaboration with IOF which made the hospital a military occupied place!
During the truce,...Parents returned to the hospital today to find their babies dead & decomposed in their cots.
27-11-2023
The Israeli military forced families to evacuate Al Nasr Hospital, leaving behind their premature babies in the intensive care unit. Israel refused to release the babies. The decomposed bodies of those babies have been found during this truce.
"Shocking scenes in this hospital, seeing babies which the Israeli soldiers refused to evacuate from this unit. According to eyewitness accounts, parents were forced to say goodbye, and leave their children to die in their beds in the intensive care unit in al Nasr Children's Hospital. To reiterate: the Israeli army forbid these children to be evacuated, or for anyone to help evacuate them from the hospital."
Source: Almashhad TV
‘Patients are dying’: What we know about Gaza hospitals under Israeli siege : They have now all stopped functioning. The al-Nasr Children’s Hospital and al-Rantisi Specialised Hospital for Children can no longer function without access to medical aid. They are also under Israeli fire. It remains unclear what has happened to the 30 children who remain at al-Nasr Hospital. (10-11-2023)
www.aljazeera.com
This is an urgent message: northern Gaza’s hospitals are in danger of imminent, full-scale Israeli military attacks. Please help us take action to protect them. 
Early Friday morning, the grounds of Shifa Hospital were targeted by an Israeli airstrike.  The Nasser Hospital has also been targeted. Attacks on Rantisi children’s hospital have caused fires, while bombardment around the Indonesian Hospital has reportedly injured displaced people sheltering in the grounds. 
These vital facilities are filled with medical staff treating thousands of wounded civilians. Meanwhile, tens of thousands of Palestinians are sheltering in the grounds, forced from their homes, hiding from Israeli bombs. 
Any attack on these hospitals would be devastating and lead to the deaths of countless innocent civilians, including children and medical staff. (map.org.uk)
10-11-2023
Gaza's hospitals are now in danger... - Medical Aid for Palestinians | Facebook
More thread on Twitter
Muath Hamed 🔻 on X: "ثريد 🔴جريمة إسرائيلية 1/7 في 10 نوفمبر أُخلي مستشفى النصر للأطفال تحت تهديد السلاح من إسرائيل، وقال مدير المستشفى للصحافة أنه تم إخلاء المرضى منه. أمس 27 نوفمبر وصل محمد بعلوشة مراسل قناة @almashhadmedia إلى المستشفى ليوثق مشهدا صادما،لجثث أطفال خدّج يخرج الدود منهم على الأسرة: https://t.co/AaiZWWjhKU" / X (twitter.com)
#محمد_بعلوشة #أطفال_غزة #مستشفى_النصر #المشهد
Doctors were forced to leave the babies behind in the hospital after they were reportedly given 30 minutes to evacuate the hospital by Israeli forces and leave patients.
استشهـ.ـدوا جوعا وعطشا وبدون رعاية طبية.. العثور على جثث أطفال متحللة في #مستشفى_النصر بعد إجبار قوات الاحتلال الإسرائيلي طاقمه والمرضى على إخلائه تثير حالة من الصدمة والغضب على منصات التواصل
Update from #ICRC : They said they didn't show any commitment toward them! Situation was difficult. https://www.facebook.com/ICRCarabic/posts/pfbid0VRa5P6hXni2E3dgWWWq2G82Ma1AbYfARNpFipNS4877mczW2uLmdFwALjdMbuRM9l
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apollopapyrus · 3 months
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Due to graphic descriptions of birth defects, listener discretion is advised.
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wisemancax · 8 months
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Lucy Letby - Retrial Decision - Crime Scene 2 Courtroom
Lucy Letby – Retrial Decision Crime Scene 2 Courtroom She’s hurt far more babies than she was charged and convicted for. She didn’t wake up one day as an evil killer. Wouldn’t be surprised to hear of more suspicious incidents under her ‘care’ over the years. Witch in the Shadow. Lucy Letby (born 4 January 1990) is a British Serial Killer…
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