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biomedgrid · 2 years

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Biomed Grid | The Mediterranean Diet: Plant Lectins as Essential Components

Opinion

In the U.S. News and World Report annual rankings (published in 2020) we note that the Mediterranean diet (Md) has, for the third year in row, been named as the overall best healthy diet. This diet is well-known for its emphasis on a high content of fruits, nuts, vegetables and whole grains. In some meals in this class of diet one can find more than 20 individual components belonging to these groups of foodstuffs. For many years now the Mediterranean way of life has been highly looked upon for health inspiration. Based on studies of Md it is now well recognised that diets rich in fruits, vegetables, fish, and healthy fats are good for us, particularly our hearts. Numerous studies have clearly shown that eating like they do in countries such as Greece, Italy, and Turkey then there is a reduced risk of suffering from heart disease. Furthermore, according to health professionals at the Mayo Clinic, those that adhere to the Md show a reduced risk of developing cancer, Parkinson’s disease, and Alzheimer’s disease. So, what makes the Md exceptional?

In my opinion one should look for a common factor among the ingredients of the Md. A recent survey of the content of fruits, nuts, vegetables and whole grains has shown that all these commodities contain varying amounts of protein molecules termed lectins. Health authorities in Western society strongly advise members of the population to adopt the “five a day” principle i.e. one should include at least five portions of plant-based material in the diet per day (approx. 400g). In actual fact health benefactors are thus advising us that a diet rich in lectins is beneficial to health! This is in stark contrast to what can be described as anti-lectin propaganda that we read in the popular press and in opinions expressed on numerous web sites. It is indeed correct that there are reports in the scientific literature (animal experiments) that have demonstrated negative effects of diets highly enriched in certain lectins.

The amounts added to these artificial diets fed to animals are, however, in most cases so high that it would be impossible for an individual following a normal diet to attain a lectin intake likely to be detrimental to health. Furthermore, there is no evidence that individuals that keep to a vegetarian diet, i.e. daily are exposed to a diet enriched in lectins, show any signs of poor health. So what are lectins? Plant lectins were discovered by Stillmark in 1888 when he observed that castor bean extracts caused agglutination of red blood cells in vitro. The word lectin (legere; from latin, means to select) was coined by Boyd in 1954 to cover a group of hemagglutinins that were able to discriminate between blood types in the ABO system. This hemagglutination property of lectins has been exploited as a useful method to identify the presence of lectins in, for example, food extracts. This approach was used by Nachbar and Oppenheim in 1980 when they reported that lectins were present in >20 common food commodities including potatoes, carrots, tomatoes, beans and peas.

Lectins are proteins that are in general resistant to low pH in the stomach and to proteolytic enzymes in the small intestine, and for some of these molecules >90% can survive passage through the gut. It is therefore evident that biologically active lectins will be present in the intestine after a meal containing raw plant material. About 80% of our immune system is associated with the alimentary canal, such that dietary lectins will provide an activation of our immunedefense apparatus. One can surmise that a diet lacking active plant lectins would result in a weakened immune system. Plant lectins have physiological effects, such as binding to glycoproteins on the epithelial surface of the small intestine, where they may elicit local and/or systemic reactions, e.g. modulation of the immune system and the micro flora in the gastrointestinal tract.

That different lectins bind to specific regions of the small intestine has been clearly demonstrated in experiments using human biopsies. In 1996 Sharma and colleagues used a panel of 27 lectins to study binding to M-cells, enterocytes, goblet cells, lymphocytes and macrophages. They clearly established that lectins with known differences in binding properties showed individual specificity with regard to which region of the small intestine they bound. For example, only 13/27 were found to bind to the M-cells of the follicle-associated epithelium and of these 5 bound to goblet cells. Although the biological significance of this is currently not known, some lectinologists speculate that lectins which have the property of binding to different cell types associated with the small intestine will initiate or trigger, separate biological responses positive for our health/well-being. The lectin, following binding to the cell, can send information into the cell´s interior via second messengers, often modulating gene expression or the lectin itself may enter the cell through endocytosis.

A large number of animal studies have clearly shown that dietary supplementation with various lectins can reduce growth of a series of different types of tumors. In their review published in 2005 Gonzalez De Mejia and Prisecaru indicate that use of plant lectins may provide novel strategies in the future for the development of new forms of cancer treatment. Beneficial effects have been reported in cases of terminal cancer where lectin-based preparations have been utilized. As mentioned earlier lectins are protein molecules meaning that they are denatured by the high temperatures met during cooking, frying, grilling etc. resulting in loss of biological activity. Thus, the importance of emphasising the need to consume raw plant material.

Dietary lectin studies are complicated by the fact that humans have consumed lectins in their habitual diet for thousands of years, making the study of individual lectins thus virtually impossible, since many may well act in concert. Furthermore, a meal would seldom consist of e.g. a single vegetable. There is indeed information indicating that when different lectin-containing preparations are mixed separately and in various proportions, then the biological responses elicited are quite unlike. Plant lectins represent an unavoidable component of a balanced diet. During the past 10- 20 years more and more studies have been addressed to the conception that lectin molecules may have an important positive impact on our health in general. Current opinion concerns the potential that lectins may have in relation to preventing illness and should therefore be regarded as health promoting components in our diet along with vitamins, minerals and other micronutrients.

In conclusion there can be no doubt that the Md is enriched in lectins and that these protein molecules can promote both positive and beneficial effects on our health. It is therefore not difficult to voice the opinion that a balanced diet containing a rich variety of fruits, vegetables and nuts will provide the necessary diversity of lectins required to stimulate biological processes in the body, forming the basis of a healthy lifestyle. Although there is much talk of the benefits of Md there is no information readily available to the general public on why a plant-based diet is positive for our health. For good health it is not simply a matter of obtaining sufficient amounts of nutrients from our food and vitamins and minerals etc. by an intake of tablets from the local drugstore, since lectins can only be obtained, not in the form of a pill, but by ingestion of raw plant material purchased at the supermarket! In my opinion more public awareness needs to be directed to the content of Md.

Read More About this Article: https://biomedgrid.com/fulltext/volume7/the-mediterranean-diet-plant-lectins-as-essential-components.001126.php

For more about: Journals on Biomedical Science :Biomed Grid | Current Issue

#biomedgrid #american journal of biomedical science & research #free medical journal #top medical open access journal

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so-many-ocs · 9 months

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Researching as a Writer

Start Broad

begin with a list of more general topics and get specific as you go.

for example, research for a historical fantasy novel might follow a chain that looks like this:

life in the 1700s -> life in 1700s france -> 1700s french etiquette and lifestyle depending on class -> 1720s french fashion for middle and upper-middle class women.

starting with a general understanding of the topic you want to cover and narrowing down to specifics will make it easier to build on your knowledge as you go.

Think Critically

consider the source. if it doesn’t cite primary sources (for example, letters and photographs from a specific era and location), what sources does it cite? follow those sources if possible.

is the information reliable? is it provided by an educational institution or an expert on the subject?

who is the author? do they present any bias? what do they have to gain by promoting a specific mindset or conclusion? has any of their research been debunked?

Anecdotes

in general, anecdotal evidence is not sufficient for academic writing. luckily for you, this is a fiction writing page, and anecdotal evidence is usually fine!

work with a combination of scholarly sources and personal experience. if you’re trying to depict a specific health condition, you might consult medical sources about the technical details of the condition, as well as seeking firsthand accounts from people who have that condition.

remember that people are not monolithic! there are often forums online where people are more than happy to discuss their experiences; cross-consult these for common elements.

Lists

keep track of your sources!! if you ever need to consult something later on, it will be way easier to open a list of resources than go digging through your search history.

additionally, if you come across lists of sources compiled by other people, save those!! you are probably not the first person to research the specific topic you’re looking into, and there are entire websites dedicated to gathering research!

wordsnstuffblog.com/research has compilations of sources for everything from writing injuries to global period pieces by century.

Resources

if you can, check out your school or public library’s websites! they will often compile scholarly resources to access for free.

look for open access or open source sites like project gutenberg that archive and digitize historical documents and other works. scienceopen and the directory of open access journals are more of these. search using keywords!

keep an eye out for websites made specifically for educational purposes (those with .edu at the end of their addresses).

#🌿 writing #writing tips #writing advice #writing resources #i'm trying to compile some instagram posts on here for easier reference #writing research

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librarycards · 2 days

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Submissions open through June 30, 2024 - Mad Dykes, Queer Worlds

Hello all! I'm editing a special issue of the literary magazine Sinister Wisdom titled Mad Dykes, Queer Worlds. If you're Mad –– regardless of personal label or diagnostic status –– and identify with some aspect of dyke experience (in all its multiplicities!), I want to consider your work for publication.

The title links to Submittable, the platform Sinister Wisdom (and most other magazines) use to process submissions. It's free to use, but can be inaccessible for visually disabled people. If that's you, email Sinister Wisdom for alternative submission options.

I am particularly interested in reading work by young/new/emerging creatives, survivors of psychiatric/medical incarceration, and/or those living outside the Global North/West. Visual art and written work are all welcome!

Note: Sinister Wisdom can't pay $; they compensate in a year-long print subscription and complementary copies of the journal. If you only submit to magazines that pay, consider checking out mine, manywor(l)ds.place; we reopen for general submissions June 1.

Feel free to email me with any further questions. Don't self-reject. ID for the image both in the alt text and below the cut.

Mad Dykes, Queer Worlds

What is Madness, and how do we, as lesbian/queer creatives, wield it? Amid much feminist discourse around the figure of the “madwoman,” mostly as an archetype to be avoided or, in some instances, appropriated, in reaction to rational distress under violently cisheteropatriarchal conditions, comparatively little discussion has focused on the lived experience of psychiatric survivorship, iatrogenic harm, and abuse under the sign of “mental illness” or psychiatric disability. Behind and beyond the figure of the madwoman, or the specter of “hysteria,” are the lived (sur)realities of Madpeople of all marginalized genders.

This issue of Sinister Wisdom seeks contributions by lesbian, queer, and/or trans people self-identified as Mad, mentally disabled, and/or psychiatric survivors. Following the portmanteaue coinages “transMad” (Cavar), “neuroqueer” (Walker, Yergeau, and Michaels-Dillon), and “neurotrans” (Smilges), Madness and (gender)queerness are deeply entangled and often inextricable from each other, both as they manifest “inside” us and in our ways of relating to our words, world(s), lovers, and friends.

What, who, and where are Mad dykes, and how do we find each other in a world increasingly oriented toward cisheteronormative, whitewashed wellness? What are the legacies and ongoing violences of queer/trans pathologization in our communities and beyond? How do we live as transMad people amid cissexist, saneist attacks from the reactionary Right? And how do we share, negotiate, or conceal our experiences of trauma, altered realities, and unfamiliar access needs while also building community?

Please submit works of any, all, or no genres, including reviews and interviews, up to 5,000 words, and a short contributor biography between 25 and 125 words. We are also seeking illustrations and photographs (.jpg or .tif files only, print resolution size at least 300 ppi). Please do not send previously published work.

Deadline for submissions: June 30, 2024

[tagging for spread hopefully! @closet-keys, @rebirthgarments, @fluoresensitive, @heavenlyyshecomes, @trans-axolotl, @fatehbaz @sawasawako @felgueirosa @bioethicists @campgender @candiedsmokedsalmon @sadhoc @osmanthusoolong @boykeats ]

#tia to everyone for sharing!!! i want to get this seen by as many ppl as possible #mine #call for submissions #madness

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ranahan · 4 months

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Free tactical medicine learning resources

If you want to learn first aid, emergency care or tactical medical care for real, you will need to practice these skills. A lot. Regularly. There’s no way to learn them just from books. But if you’re looking to supplement your training, can’t access hands on training, are a layperson doing research for your writing or otherwise just curious, here are some free resources (some may need a free account to access them).

TCCC

The current gold standard in the field is Tactical Combat Casualty Care (TCCC), developed by the US army but used by militaries around the world. There is also a civilian version of the system called Tactical Emergency Casualty Care (TECC). Training materials, Standards of Care, instructional videos, etc. can be accessed at deployedmedicine.com. You’ll need a free account. This should be your first and possibly only stop.

There’s also an app and a podcast if those are more your thing, although I haven’t personally tried them.

More TCCC (video) resources

STOP THE BLEED® Interactive Course

TCCC-MP Guidelines and Curriculum presentations and training videos

EURMED’s Medical Beginner's Resource List has suggested list of video materials (disclaimer: I haven’t watched the playlists, but I have been trained by nearly all of the linked systems/organisations and can vouch for them)

Tactical Medical Solutions training resource page (requires registration; some of the courses are free)

North American Rescue video downloads

Emergency medicine

WHO-ICRC Basic Emergency Care: approach to the acutely ill and injured — an open-access course workbook for basic emergency care with limited resources

Global Health Emergency Medicine — open-access, evidence-based, peer-reviewed emergency medicine modules designed for teachers and learners in low-resource health setting

AFEM Resources — curricula, lecture bank, reviews, etc.

Global Emergency Medicine Academy Resources (links to more resources)

OpenStax Anatomy and Physiology textbook

Open-access anatomy and physiology learning resources

Principles of Pharmacology – Study Guide

Multiple Casualty Incidents

Management of Multiple Casualty Incidents lecture

Bombings: Injury Patterns and Care blast injuries course (scroll down on the page)

Borden Institute has medical textbooks about biological, chemical and nuclear threats

Psychological first aid: Guide for field workers

Prolonged field care

When the evac isn’t coming anytime soon.

Prolonged Field Care Basics lecture (requires registration)

Aerie 14th Edition Wilderness Medicine Manual (textbook)

Austere Emergency Medical Support (AEMS) Field Guide (textbook)

Prolonged Casualty Care (PCC) Guidelines

Wilderness Medical Society Clinical Practice Guidelines

Austere Medicine Resources: Practice Guidelines — a great resource of WMS, PFC, TCCC, etc. clinical practice guidelines in one place

The Wilderness and Environmental Medicine Journal (you can read past issues without a membership)

Prolonged Field Care Collective: Resources

National Park Services Emergency Medical Services Resources

Guerilla Medicine: An Introduction to the Concepts of Austere Medicine in Asymmetric Conflicts (article)

Mental health & PTSD

National Center for PTSD

Psychological first aid: Guide for field workers

Combat and Operational Behavioral Health (medical textbook)

Resources for doctors and medical students

Or you know, other curious people who aren’t afraid of medical jargon.

Borden Institute Military Medical Textbooks and Resources — suggestions: start with Fundamentals of Military Medicine; mechanism of injury of conventional weapons; these two volumes on medical aspects of operating in extreme environments; psychosocial aspects of military medicine; or Combat Anesthesia

Emergency War Surgery textbook and lectures

Disaster Health Core Curriculum — online course for health professionals

Médecins Sans Frontières Clinical guidelines

Pocket book of hospital care for children: Second edition — guidelines for the management of common childhood illnesses in low resource settings

Grey’s Quick Reference: Basic Protocols in Paediatrics and Internal Medicine For Resource Limited Settings

The Department of Defense Center of Excellence for Trauma: Trauma Care Resources (links to more resources)

#feel free to share and add more #tactical medicine #tactical combat casualty care #prolonged field care #austere medicine #military medicine #tccc #tecc #disaster medicine #wilderness medicine #emergency medicine #emergency medical services #learning resources #writing resources #mandalorian medics #paramedicine #medicine

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brownsugar-dreams · 2 years

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21 Day Healthy Wealthy Body Cleanse

IF YOU'RE READING THIS IT’S YOUR SIGN TO KICKSTART A WHOLE NEW WAY OF LIVING BEFORE THIS YEAR IS OVER!

Leveling up is an ongoing journey. Lately I’ve been feeling the need to do a cleanse and welcome in new energy. I’m thinking a 21 day cleanse that incorporates mind, body, spirit exercises. One of the hardest parts about doing cleanses is not having someone to keep you accountable. If you’ve been wanting to do a cleanse, join the program where you can track your progress, connect with people who are also doing the cleanse, and get recipe ideas. You can join free anytime before the start date!

“Rules”

The first cleanse will be a liquid diet and will start on Monday October 10, 2022!

Always check with your doctor before starting any new changes to your diet, especially if you have medical issues.

For this cleanse you will need:

1. A juicer, blender, or citrus press

2. Fresh fruit and/or vegetables (preferably organic and in season)

Juice for breakfast

Juice for lunch

Juice for snack

Juice for dinner

Juicing Recipes: The Juicing Bible is an excellent resource. Amazon link: https://amzn.to/3qEsKBb

I’ll also post some recipes in the program group tab

3. Water, water, water! 💦 Water keeps you hydrated, clears skin blemishes, and normalizes your digestive system. Making sure that you are well hydrated during your cleanse is very important. You need to drink at least half of your body weight in water every day. For example if you weigh 150 lbs, you need to drink 75 ounces of water each day= 9 1/2 8 ounce glasses per day.

4. A lemon in at least 1 glass of water per day = 21 lemons for your water for the 21 days of this cleanse.

5. A gratitude journal to help you work on cleansing your spirit. Everyday when you wake up instead of grabbing your phone take a few deep breaths and cultivate a feeling of gratitude. Pull out your gratitude journal and write down one thing you are grateful for. You can do this while sipping on some lemon water.

6. Practice meditation for 5-10 minutes each day. This might be hard for some people but if you can attempt meditation after writing in your gratitude journal it’ll get easier each day.

7. $21 dollars. Give $1 away each day to a stranger. This can be in the form of a tip, charity, or just sending $1 to someone random each day. This will open up the reciprocation of universal energy of abundance and prosperity. If you’re unfamiliar with the flow of money, listen to this podcast episode.

Do your daily check-ins right on the program which you can access on my website or the app.

Remember you are in control! If you want to do 2-3 days or 5-7 days or do 10-21 or more days the choice is yours! Take it one day at a time, listen to your body, and again check with doctor! I’m super excited! I can’t wait to hear about the amazing things that are going to manifest over the next few weeks. Let’s go!

#wellness #diettips #healthy #health & fitness #levelup #21 day smoothie diet plan #sugar lifestyle #challenge #sugar bowl

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hier--soir · 8 months

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hi dude. i’m sorry if this is overstepping a boundary or anything, and if you’re not comfortable sharing please absolutely delete this ask, but i just wondered if you had any advice for getting through the old d*pr*ssion. i’m really struggling right now and i’m too fucking anxious to reach out to anyone for help, just wondered if you had any words of wisdom?

your writing fucking blows my mind btw. i am honored to exist at the same time as u to witness how insanely talented you are 🤍 cheers to u

hey legend! [this is long as fuck my bad]

you wanna know something super impressive? that thing you mention that's really hard, that thing that makes us all so anxious sometimes, that sometimes fucked up sometimes painful sometimes shameful thing called reaching out ? you just did it by sending me this, and i'm pretty proud of you dude.

depression is by no means fun and games, and i'm really sorry you're struggling. i know all too well how isolating it can be. how dark it can feel. but these feelings are not forever. and these feelings are not who you are.

first, i hope it's okay that i share something that i think about all of the fucking time, that i resonate with, that i feel deep in the marrow of my bones. it's a talk wentworth miller gave at an Active Minds conference a few years back, about his experience living with and talking about depression.

“Sharing my story is, and has been, life saving for me. And it's scary, still. Because whenever I do it, whenever I write or talk about the things the younger me worked so hard, for so long, to keep quiet, whenever I find the courage to say 'yes, me too'... it's like opening a door and walking alone into a pitch-black room, and it's dark, and I have to feel my way, and it's frightening. And then I find the light switch, and I turn on the light, and I see I am surrounded. I see a room full of people. There are so many of us. In here, and out there."

there are so many of us my friend. you are not alone in this. you just need to turn on the light.

more under the cut x

something i've been doing for the past two years is journalling. i do it everyday, chicken-scrawling the most minute details and thoughts from my day. and in hard times, like the past month, i journal twice a day. i start it off in the morning with a few goals, or ideas, of what i'd like to do that day. super simple stuff. and at the end of the day, i write what i ended up actually doing. and whether or not i did or didn't achieve what i set out to do, i get to look at the beginning and end of my day and acknowledge the quietest and the loudest parts of it. it's sometimes bad and sometimes awful. but sometimes? it's great.

here's a pic of my journal one day like a fortnight ago [mind the handwriting lol]

i look back at this day and i think it was sunny, you felt love, you felt proud. and with everyday that passes after this one, i'm grateful to myself for making these entries. on days where it rains, where i do not feel love, where i do not feel proud - i look back and remember that it is possible. i've felt good things, fantastic wonderful things, and i will feel them again.

things like medication and talk therapy work for me but don't necessarily work for everyone, so i won't say these things are an end all be all. if you have the capacity, even reaching out to a doctor you feel comfortable with can help. it's worth expressing how you've been feeling and how it has been affecting parts of your life. to tell one person can feel like climbing a mountain, i know. but please trust me, the view at the top of that mountain??? fucking incredible.

if reaching out to someone in person still feels too tricky, you could access an anonymous hotline. in australia we have things like Headspace and BeyondBlue, where you can reach out over the phone or online chat and speak anonymously, for free. just get something off your chest, say anything you feel, say whatever is bubbling up with seemingly nowhere to go - to a stranger. i've accessed this kind of support before and found that it took a bit of weight of my shoulders - maybe this is something that could bring some relief to you as well. if people in other countries are aware of and willing to share their home country's version of this in the comments, that would be lovely. if not, that's also fine.

i hope this response has felt meaningful in some way for you, and not just a mess of ramblings..

i guess i’ll end this by saying i may not know you but best believe that i care for you. i believe in you, and i'm thinking about you, wherever you are. you'll get a special mention in my journal tomorrow morning x

#anon #tw mental health #tw depression #personal #very personal actually

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letitrainathousandflames · 2 years

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They're opening more units of free medical care for trans people in my country.

I just saw it on the news, they interviewed a trans man talking happily about how pleased he is to finally have access to gynecological care free of judgement, and a nonbinary person saying they were happy to have their pronouns respected, and a trans lady pleasantly surprised at the lack of deadnaming from the workers there. The reception desk has a huge trans flag hanging from it.

Idk there's something deeply heartwarming about seeing trans/nb people celebrating their rights at the daytime news. I hope to see more inclusive journalism that normalizes trans lives like that. 💕

#gender stuff #trans positivity #nb positivity

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literaturepublishersjournal · 1 year

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Toxicity Case Reports Journal

Toxicity Case Reports Journal publishes case reports in Toxicity journal, images in Toxicity Case Reports Journal , journal of Toxicity case reports, case reports in Toxicology journal, journal of Toxicology case reports etc. Toxicity literally means poisonous or noxious and logos refers to the underlying science that explains the adverse effects of toxicity at the organismal level.

Toxicology is therefore a multidisciplinary field which is at the interface of Biology, Chemistry and Medicine, with a special focus on Pharmacology. The subject discusses the presence of physical, biological and chemical agents in the Biological system and the way they affect its functions. Toxicology places special emphasis on the dosage of toxic substances, the route of exposure, species, age, sex, and the environment.

Toxicology: Case Reports Journal

Journal of Toxicology Case Reports is an Open Access journal published. The Journal publishes original research articles, review articles, and clinical studies in all areas of toxicology. Open access publishing proposes a relatively new model for scholarly journal publishing that provides immediate, worldwide, barrier-free access to the full-text of all published articles.

Open access allows all interested readers to view, download, print, and redistribute any article without a subscription, enabling far greater distribution of an author's work than the traditional subscription-based publishing model. The journal uses an editorial tracking system that helps in providing good quality in the review process.

Toxicity Case Reports Journal Highlights: Aflatoxins, Cardiac Toxicity, Chemical Toxicology, Developmental Toxicology, Drug Toxicity, Heavy Metal Toxicity, Heavy Metal Toxins, Industrial Hygiene Toxicology, Insecticides Toxicology, Metal Toxicology, Nano Toxicology, Pesticidal Toxicology, Renal Toxicity, Reproductive Toxicology, Skin Toxicology, Tetanus Toxin, Toxicogenomics, Toxicology Reports, Toxicology Testing.

Journal of Forensic Toxicology & Pharmacology

Journal of Forensic Toxicology & Pharmacology: Journal of Forensic Toxicology and Pharmacology is a peer-reviewed scholarly journal and aims to publish articles in all areas of forensic toxicology, forensic science and pharmacology. The field of forensic science has come a long way and this is particularly true in the area of forensic toxicology, which is both fascinating and important for many applications.

Forensic toxicology is a discipline of forensic science which aids in medical or legal death investigation including disciplines such as analytical chemistry, pharmacology and clinical chemistry. Journal highlights include: Analytical Chemistry, Anthropometry, Clinical Chemistry, Clinical Pharmacology, Computer Forensics, Digital Forensics, Drug Chemistry, Drugs of abuse, Environmental Forensics Fingerprints, Forensic Criminology, Forensic Death Investigation, Forensic Dentistry, Forensic Engineering, Forensic Genetics, Forensic Medicine, Forensic Neuropsychology, Forensic Pathology, Forensic Pharmacology, Forensic Psychiatry, Forensic Science, Forensic Toxicology, Medical and Clinical Toxicology

Related Journals: Forensic Toxicology, Indian Journal of Forensic Medicine & Toxicology, Forensic Science International, Forensic Science International: Genetics, Journal of Forensic Sciences, Forensic Science, Medicine, and Pathology, Journal of Analytical Toxicology, Clinical Toxicology, Environmental Toxicology and Pharmacology, Journal of Pharmacology and Toxicological Studies

International Journal of Chemical Sciences: International Journal of Chemical Sciences is a peer reviewed Quarterly Research Journal encompassing all the branches of Chemical Sciences like Inorganic, Organic, Physical, Analytical, Biological, Pharmaceutical, Industrial, Environmental, Agro and Soil Chemistry as well as Chemical Physics and Engineering etc

American Journal of Drug Delivery and Therapeutics

American Journal of Drug Delivery and Therapeutics: American Journal of Drug Delivery and Therapeutics is an open access peer reviewed and bi-monthly published research journal that publishes articles in the field of Drug Delivery and Therapeutics. It is an international journal to encourage research publication to research scholars, academicians, professionals and students engaged in their respective fields.

Our mission is to advance research by working to develop and maintain competence, ethics and integrity and the highest professional standards in the specialty for the benefit of the public. The faculty seeks, through its activities, to bring about an improvement in research of the public.

American Journal of Drug Delivery and Therapeutics is an international, peer-reviewed, open access online journal publishing original research, reviews focusing on all aspects of drug delivery systems.

Specific topics in the journal include: The properties and design of drugs, Excipients and drug penetration enhancers, Vaccines, Nanotechnology in therapeutics, Polymers for drug delivery, Drug delivery systems including oral, nasal, pulmonary, parenteral, topical and transdermal Controlled release systems; nanoparticles, microparticles, microcapsules, liposomes. Pharmacokinetics, pharmacodynamics, Biopharmaceutics, Medical devices.

Der Chemica Sinica

Der Chemica Sinica: The primary mission of the Der chemica Sinica is to become the premier source of high quality research from the whole of the world. All authors not only receive fast and comprehensive peer-review but also the article promotion to researchers working in the same field. Der chemica Sinica is peer-reviewed and is published in electronic version.

The language of the Der chemica Sinica is English.Der chemica Sinica is an Open Access that aims to publish a complete and reliable source of information on discoveries and current developments as original articles, review articles, case reports, short communications, etc. in all areas of the chemistry science and making them available online without any subscriptions to the researchers worldwide. The editors welcome articles in this multidisciplinary field of chemistry.

Chemical Informatics

Chemical Informatics: Chemical Informatics is a vast field that aims to disseminate information regarding the design, structures, creation, dissemination, analysis, visualisation and the use of chemical information.

Chemical Informatics Journal aims to supply scientists of resources in order to provide the scientific knowledge through the publication of peer-reviewed, high quality, scientific papers and other material on all topics related to Chemical information, Software and databases, Molecular modelling, Computer- aided drug design, Molecular graphics, Data mining techniques, QSAR, Use of chemical structures and their representation in chemical substance and chemical reaction databases. Journal Highlights: Models of Chemistry, Chemical Databases and Maintenance, Chemical Information, QSAR, Data Mining Techniques, Database Software

Related Journals: Journal of Cheminformatics, Journal of Molecular Modeling, Journal of Molecular Structure, Journal of Molecular Graphics and Modelling, Drug Discovery Today.

Journal of Medical Toxicology and Clinical Forensic Medicine

Journal of Medical Toxicology and Clinical Forensic Medicine: Journal of Medical Toxicology and Clinical Forensic Medicine is a Scholarly Open Access scientific journal which deals with both toxicology and Forensic medicine. Medical Toxicology is nothing but a medical subspecialty concentrating on the analysis, supervision and prevention of harming and additional adversative health issues due to medicines, work-related and ecological contaminants, and organic causes.

Clinical Forensic Medicine (CFM) is a health field which deals with the collaboration of clinical medicine and the law. It is also involved in the examination of healthcare doctors who are believed to be impaired or may be a possible risk to the public for other reasons. Journal Highlights includes: Forensic Analysis, Forensic Pathology, Toxicology, Forensic Technologies, Forensic Science, Clinical Forensic Analysis, DNA FingerPrinting, Crime investigation, Toxicity Analysis, Jurisdiction

Related Journals: Forensic Nursing, Autopsy, Nanotoxicology, Forensic Science, Journal of Forensic Sciences, Forensic Science International, International Journal of Legal Medicine, Journal of Forensic and Legal Medicine, Legal Medicine, Toxicology, Environmental Toxicology and Chemistry, Critical Reviews in Toxicology, Regulatory Toxicology and Pharmacology; Environmental Toxicology, Clinical Toxicology, Journal of Applied Toxicology, The American Journal of Forensic Medicine and Pathology, Journal of Indian Academy of Forensic Medicine, Indian Journal of Forensic Medicine & Toxicology, Journal of Clinical Forensic Medicine.

Journal of Heavy Metal Toxicity and Diseases

Journal of Heavy Metal Toxicity and Diseases: Heavy Metal Toxicity refers to an overexposure to lead, mercury, arsenic, cadmium, chromium or other high density or metallic element that causes irritation or damage to the body.

Heavy metals can be found naturally in the environment, in homes, or at the workplace. Sudden severe exposures as well as moderate exposures over time can cause toxicity. Depending on the exposure, metals can increase cancer risk, impair production of red and white blood cells, causes Nausea, Vomiting, Rice-water diarrhoea, Encephalopathy, MODS, LoQTS, Painful neuropathy, Blue vomitus, GI irritation/ Haemorrhage, Hemolysis, MODS (ingested); MFF (inhaled), Vomiting, GI Haemorrhage, Cardiac depression, Metabolic acidosis, Very high doses: Haemorrhage, Bone marrow Suppression, Pulmonary Edema, Hepatorenal necrosis.The main aim of this journal is to provide the quality of data on Heavy Metal Toxicity and related diseases due to severe exposure to Heavy Metals.

Related Journals: The New England Journal of Medicine, Blood Transfusion, Medicine and Healthcare Journal, Iron Chelation Therapy Journal, Blood Journal, Scientific World Journal, Global Journal of Medical Research, Occupational Medicine & Health Affairs Journal, Journal of Experimental Botany, Iranian Journal of Toxicology, Journal of Heavy Metals Toxicity and the Environment, International Journal of Toxicology Heavy Metal Poisoning and Cardiovascular Disease, Heavy metal poisoning from Ayurvedic medicines.

Authors are requested to submit their manuscript by using Online Manuscript Submission Portal:https://www.literaturepublishers.org/submit.html

For more information on Literature Publishers - Toxicity Case Reports Journal visit our site:- https://www.literaturepublishers.org/event/Toxicity-Case-Reports-Journal.html

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anonymouslydisabled · 2 years

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intro post!

This is my introductory post to this new blog!

You can call me frog. I’m 15 years old and primarily use he/him pronouns. I have a lot of medical issues and not a lot of access to medical care. This account is for me to talk about my experiences with various disabilities and neurodivergencies.

DNI:

- Against educated self diagnosis or suspicion of disorders.

- Racist, ableist, zionist, homphobic, shitty in any way like that.

- A terf or queer exclusionist.

- NSFW, pro SH or pro ED accounts

- If you think cripplepunk is for mentally disabled and/or neurodivergent folks.

My main special interest is frogs. Additionally I enjoy fiction podcasts, disability awareness, journaling, writing and reading. I am completely open to being messaged about any of my interests or disability stuff as long as you’re respectful, not on my DNI, and also a minor.

I have limited access to medical care. I do an immense amount of research on my symptoms before speaking on them, but please feel free to correct me. I talk about a lot of my experiences ranging from neurodiverse things such as seizures and suspected autism to psychical things like suspected POTS and chronic pain.

I have a lot of disabling symptoms, likely caused by a lot of different things and that’s not me trying to be “quirky” that is literally just my life. It sucks a lot more for me than it does for you.

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gender-affirmingcare · 1 month

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Impact of Gender-Affirming Care Bans on Transgender and Gender Diverse Youth: Parental Figures’ Perspective

Abreu, Roberto L., Jules P. Sostre, Kirsten A. Gonzalez, Gabriel M. Lockett, Em Matsuno, Della V. Mosley. 2022. “Impact of Gender-Affirming Care Bans on Transgender and Gender Diverse Youth: Parental Figures’ Perspective.” Journal of Family Psychology 36(5):643–52.

Critical Review # 1

"Impact of Gender-Affirming Care Bans on Transgender and Gender Diverse Youth: Parental Figures’ Perspective" is a study that explains the experiences of TGD (transgender and gender diverse) youth and what it is like to be a parental figure during these times. The article begins by explaining how TGD youth face an unprecedented number of systemic barriers that affect their physical and mental health, and many of these barriers come from legislators/policymakers making laws, bans, and bills that prevent the youth from getting the care they need (Abreu et al., 2022). The article mentions how there are many trans prejudices, where trans women and girls of color find themselves most affected, "because of the intersection of racism, cisgenderism, and sexism. Facing intersectional discrimination results in transgender women and girls of color experiencing higher rates of negative health outcomes and exposure to higher rates of violence, with transgender women of color making up 73% of transgender murders in 2020. Additionally, transgender youth experience disproportionately high numbers of homelessness when compared to their cisgender counterparts," (Abreu et al., 2022).

In the United States, many red states have enacted bills to ban gender-affirming care for TGD youth. For example, in Arkansas, the "Save Adolescents From Experimentation (SAFE) Act" was passed in 2021, prohibiting gender-affirming treatments for minors, including hormone therapy and puberty blockers. Texas proposed Senate Bill 1311 in 2021, seeking to classify gender-affirming care for transgender youth as child abuse, potentially subjecting parents and healthcare providers to criminal penalties. Similarly, Tennessee introduced House Bill 578 and Senate Bill 657 in 2021, aiming to restrict access to gender-affirming treatments for minors. With that, the authors of this article conducted a study to gain insight into parental figures who have TGD children from February 27th to March 20th, 2020. "The aim of this study is to explore parental figures’ perspectives on how bans on gender-affirming care impact their TGD child," (Abreu et al., 2022). The study included 134 parental figures who participated in an online free-response survey, and participants’ ages ranged from 28 to 68, residing in 37 states. The participants’ race/ethnicity ranged from White, Hispanic, Asian American/Pacific Islander, and multiracial. Participants reported their child’s current age between 5-10 years old, 11-15 years old, 16-20 years old, and 21 and older. While participating in the study, parental figures were asked open-ended questions, such as, “What are your reactions to these bills/laws being imposed and/or passed?” and “What would you like for legislators to know in response to these proposed bills/laws?” (Abreu et al., 2022). What researchers found were five themes among the youth that are a result of these antitransgender laws on TGD youth. These include depression and suicidal ideation/risk of suicide, anxiety, increased gender dysphoria, decreased safety and increased stigma, and lack of access to medical care. Some participants gave their advice to legislators/lawmakers regarding these antitransgender laws. "Thirty-seven parental figures advised that TGD youth healthcare should not be controlled by the government or politics but instead by medical professionals, parents, and TGD youth themselves," (Abreu et al., 2022).

This study relates to the research topic of gender-affirming care because the parental perspectives on these antitransgender bans highlight the dire consequences of legislative bans on gender-affirming care for transgender and gender diverse (TGD) youth. It elucidates how such bans exacerbate mental health issues, increase gender dysphoria, compromise safety, and impede access to vital medical treatments. The parental figures' advocacy underscores the crucial role of healthcare decisions being guided by medical professionals, parents, and the TGD individuals themselves rather than political agendas. Ultimately, this study underscores the critical importance of gender-affirming care in supporting the well-being and rights of TGD youth.

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biomedres · 1 year

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Nocturnal Activities and Strategies for Self-Protection Against Human-Vectors Contact in a Peri-Urban Community in Lafia, Nasarawa State, Nigeria

Nocturnal Activities and Strategies for Self-Protection Against Human-Vectors Contact in a Peri-Urban Community in Lafia, Nasarawa State, Nigeria in Biomedical Journal of Scientific & Technical Research

https://biomedres.us/fulltexts/BJSTR.MS.ID.005975.php

joy protection from long lasting insecticide treated nets (LLINs) or other control measures due to human and vector behaviours that promote contact between man and vector mosquitoes outside the safe havens of LLINs and other protections against mosquitoes bites. Thus, the study on peri-urban dwellers nocturnal activities and strategies for self-protection against human-vector contact in Mararraba-Akunza, Lafia, Nasarawa State, Nigeria was carried out between December 2016 and January 2017. A well-structured questionnaire on human nocturnal activities that predisposes them to mosquitoes bites was administered to 30 randomly selected households. Result obtained showed that most people sleep outdoor during the hot months between January and March 63.3% (19/30) and thus there was a very high significant difference (P < 0.0001) in relation to the proportion of sleepers between in-and-outdoor points. Almost all respondents 96.67% (29/30) when resting outdoors use a form of protection against mosquito bite. The main outdoor activity that predisposes the people to mosquitoes bites was watching television. Thus, there was a high significant variation (P < 0.01) across predisposing outdoor activities. Also, the proportion of outdoor sleepers across the four quarters of the year highly varied significantly (P < 0.0001). Almost all respondents 70% (21/30) sleep till daybreak and majority of them use insecticide outdoors 43.33% (13) but when indoors most of them sleep under LLINs 66.7% (20/30). The outdoor nocturnal activities of people in the study community will continually expose them to mosquito vectors bites due to high temperature of the lowland area which can only be supported through provision of stable electrical power supply in order for the periurban inhabitants to remain indoors at night. Also, LLINs should be made available to the inhabitants, and they in turn should ensure it is hung outdoor especially during the dry season period so as to avoid contact with mosquitoes.

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biomedgrid · 2 years

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Biomed Grid | Titanium Implant Devices: Increase Biocompatibility or Decrease Drug Release Rate?

Mini-Review

Titanium and its alloys are the most used metallic materials for the manufacture of orthopedic and dental prostheses due to their similarities to human bone. Among these properties, the hardness and Young’s modulus stand out, besides being chemically inert and presenting low corrosion potential in biological environments [1]. Its low corrosion rate is due to the formation of a TiO2 layer, also known as a “barrier oxide” responsible for metal passivation.

TiO2 formation is a thermodynamically favorable process, and an oxide of a few nanometer thicknesses is formed as soon as the metal is exposed to an oxygen-containing environment. Due to this factor, the characteristics of the coating can be easily experimentally manipulated. One of the techniques that have been widely used for implant surface modification is anodization. Through this technique, it is possible to create from compact films, as pores of the order of micrometers, or even nanotubes that can have diameters ranging from 30-100nm [2, 3].

Over the course of several years, much effort has been put into the development of these structures as well as their possible applications. It is now possible to obtain highly organized nanostructures of 100-1000μm in length, which can undoubtedly have many advantages for applications requiring materials with a high surface area. For implantable materials, nanoarchitecture provides a large area for osteoblast growth and cell differentiation, which favors the osseointegration process. With all these characteristics, it was not difficult to think about the possibility of using implants with nanostructured surfaces to produce drug delivery devices.

The main problem with the placement of orthopedic and dental implants is the rejection of the material by the human body. The process of implant rejection usually occurs by contamination of the material with microorganisms, with Staphylococcus Aureus being the most common, which grows on the implant forming a bacterial biofilm. After the formation of this biofilm, it is practically impossible to recover the surface of the biomaterial. Thus, an idea to reduce the incidence of this problem could be the incorporation of antimicrobial drugs. Such devices would act locally, reducing the amount of intravenous or oral drugs prescribed to patients postoperatively.

Several studies have proven the potential of this material to produce this device. Two properties are desirable in these materials, the first one is the bioactivity, i.e., the ability of the implant to Osseo integrate. Such ability is observed in materials with high wettability, which facilitates adhesion of osteoblastic cells and facilitates the osseointegration process. The other important feature is a slow drug release rate so that the drug concentration in the bloodstream remains within the range required for inhibition of the microorganisms. The problem with this latter feature is that the antimicrobial drugs used are water-soluble, so the wettability of the device is once again of great importance in the development of the material, but in an antagonistic manner.

The lower the wettability, the lower the drug release rate. Many works show the addition of diffusional barriers to the implant surface to decrease the drug release rate [4, 5]. However, the great effort made to obtain a large surface area is lost in this case. Although coatings with smaller nanotubes have larger surface areas, the effect of capillarity on these materials is more pronounced and cannot be neglected in the development of biomaterials of this kind [5]. Therefore, further investigation of the ideal conditions for a high osseointegration rate coupled with a low drug release rate is needed. In recent studies we observed that nanotubular films incorporated with cefazolin can release 1mg of the drug in 8min or 300min, depending on the experimental conditions of the biomaterial synthesis [5]. However, the question that remains is what would be the ideal condition? A lot of research is still needed to answer this question.

Read More About this Article: https://biomedgrid.com/fulltext/volume7/titanium-implant-devices-increase-biocompatibility-or-decrease-drug-release-rate.001106.php

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blushydiorrb · 1 month

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blushydior

safety tips for victims of abuse that’ve helped me

safety plans are essential when dealing with abuse and although not everyone has the same level of situations, i make this post to share what i did that helped me get through and hopefully help you or even give you ideas.

while you are still living with your abuser(s) + preparing to leave:

get an envelope or folder that holds all of your important documents and items:

spare car keys

social security card

birth certificate

pay stubs

insurance cards

proof of pet care/ownership.

a usb with evidence of abuse, receipts of animal care (more info in respective categories below) *

look up trusted homeless shelters. write down the phone numbers and addresses. if you have a pet, there are shelters who support domestic violence victims and take pets in while you take care of yourself first. keep this paper in the envelope.

paper is important. your phone may be out of battery or when you’re far from home, you have no service/data.

note: dialing 911 is always free at pay phones

- prepare a bag for an emergency escape

keep the following items:

extra pants, shirt, undergarments for you and the children

toothbrush, toothpaste

cash (gas, food…)

chargers

medication for you and your companions

car keys, bus card

the papers with written resources we prepared beforehand.

the usb

if you have pets: water bottles, food in a carryon, collar, leash!

- keep your safety bag in an easy access place so you can grab it in a hurry. in a car, in the backyard, a friends or neighbors house, workplace, gym locker, etc. if this isn’t possible, don’t worry. getting out safely is much more important.

things to record for evidence of abuse:

photos of inflicted wounds

photos of items damaged by abuser

a journal where you wrote about your experiences

screenshots/saved text messages, voicemails, letters, voice recordings, emails of threats

if you were treated at a hospital for your injuries, keep a copy of those records.

* keep these on a usb or online drive so that it’s easily accessible for the police to have.

- tell someone you trust about what you’re going through. ask if their place is always opened to you in situations of distress. don’t be scared to ask for help especially when it comes to your safety. i was afraid to open up as well but once i did, i felt better because i was seen and felt secure. it was nonsense to feel that way. they will be really happy to help you.

- in situations where the abuser has a hot and cold, unpredictable behavior:

try to make sense of their abusive patterns and triggers. take notice of the signs so you can get yourself and others to safety.

make sure you develop coping skills that work for you, know where to be in the house, away from any stashed weapons.

avoid the kitchen, garage, backyard— any rooms where there are hard floors & table corners.

pitch in an idea to get a carpet in the main room just in case a violent situation occurs.

when you’re at home, take off any restrictive clothing & long, easy to reach jewelry so your abuser won’t use it to hurt you.

- when violence occurs,

protect yourself without fighting back. make yourself small. curl up into a ball, in a corner: put your head into your knees & arms, block your temples.

try your best to not run towards the children and animals as their next target will be them too.

create a code phase like “did you call earlier? i’m sorry i missed it.” or “i made your favorite. would you like some packed?” with a trusted neighbor if you need a hand calling for the police. try to make it look like you call them time to time in leisure so that it doesn’t seem off to your abuser(s).

- if you have left and your abuser is on your tail, dial the police and ask them to stay on call with you in case you need help.

- when escaping, try to be unpredictable; leave when your abuser least expects it

be sure to not leave any hints of where you will be going,

go to a place where they wont be likely to find you but is also a place where you feel safe and comfortable.

- if your abuser was arrested, ask if they will be held in custody + expected release date. give the police any information so they can make use of it for the release conditions. keep a copy of this information.

if you have animals:

abusers can also threaten your animal(s) to hold leverage over you & further prove that they’re in control. there’s a chance where you may have to prove ownership and care of the pet,

gather: bills and receipts (grooming, vet appointments, emergency visits) that you have paid for under your name, photos, videos of training, caregiving and place them on a USB or an online drive (google drive, email, etc) *

in this usb you can also have your resume, working permit, any other important things on your devices.

if it’s possible in your state, try to get your animals under your protection order.

read this article for more information on animal and family violence to help you out more.

if you have children:

create a code word with them so they know when to call for help. review this with them frequently in private so that they remember.

teach them how to use a phone and what number(s) to dial + what to say. for other contacts, keep a paper with the numbers in handy. again, review this procedure with them frequently.

make sure they know to keep the game/procedure between you and them!

tell them that it’s not their fault this is happening. educate them on why the behavior they receive is not right.

EXTRA TIPS

if you have a car, make sure you always have at least a half tank of gas.

consider buying safety/medical alert alarms, defense kits, portable door locks, a security door alarm wedge for when you reach your temporary safe place or live alone.

find out ways you can pull out of the driveway easily, make sure you aren’t blocked by any chance.

make use of the speed dial options on your phone.

make it a habit to delete your browsing history of anything that will rise suspicions

if you find this post helpful, review this post frequently so you can remember the information and be well prepared and bookmark/print this post and store it under a false name or the envelope.

open up a bank account in your own name to increase independency.

things to remember:

you are not obligated to stay with anyone / in any situation where you are emotionally/physically abused no matter how long you’ve known them and the bond you used to have.

no one deserves to be abused. nothing is ever your fault. you’re seen. you are so much more than how you are treated. i love you. you. are. loved.

don’t condition or down play your trauma and experiences. don’t compare yourself to others. no one’s situation is “worse” than another’s — all and any forms of traumatic experiences are equally important and deserve undivided, careful attention.

listen to your gut. if you feel the sudden, most important urge not to enter a room, say the next thought, or that you should leave, do it. don’t hesitate. you can figure out the reason later.

#blushydior

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