"Brother Louie" is a song by German duo Modern Talking, released as the lead single from their third studio album, Ready for Romance (1986). It was their fourth consecutive single to top the German Singles Chart, after "You're My Heart, You're My Soul", "You Can Win If You Want" and "Cheri, Cheri Lady".
"Brother Louie" reached #1 in Germany. The single spent four weeks at the top and total of 17 weeks on the German chart. It also went #1 in Finland, Sweden, Spain, Greece, and South Africa.
In 1998, not long after the duo's reunion, a remixed version of the single was released, titled "Brother Louie '98". The single, released in a new sleeve, was also successful.
The music video of "Brother Louie" contains footage from the 1984 film Once Upon a Time in America, interspersed with the band members playing on a stage surrounded by dancing fans.
It received 65,7% total yes votes!