#Hope in Treatment

[ecomehdi]

Cancer Research: Scientists Triumph in Taming the Protein of Severe Cancer Cases 24

In the realm of medical breakthroughs, scientists have achieved a remarkable feat in the battle against severe cancer cases. The focus of their triumph? Taming the elusive protein that plays a pivotal role in these challenging scenarios. Join us on this journey as we unravel the science, the victories, and the hope that comes with this groundbreaking achievement. Protein Unveiled: A Culprit in…

View On WordPress

#Cancer Breakthrough #Cancer research #Hope in Treatment #Medical advancements #Medical Discoveries #Personalized Therapies #Precision Medicine #Protein Taming #Scientific Triumph #Severe Cancer Cases

[circuscountdowns]

I just don’t think the bishops would’ve stood by while lamb puts shamura in the pillory

#Maybe one day I’ll give this one a treatment and make it clean. 4 now I just needed it out of my head hope it’s readable as is! #Yknow how there’s so much more u want to say in a comic but with comics it’s a race on with attention and drive.yeahg #cotl art

[bullagit]

due to personal reasons i am now firmly on team “i hope aziraphale does change heaven for the better actually (going on the assumption that his return is as straightforward as it seemed etc” 

like if the alternative is just this ohhh he’s so NAIVE and SOFT and so WRONG and he’ll have to LEARN A TOUGH LESSON etc etc nonsense then yeah 1000% go for it babe knock it out of the park

i hope choosing hope and kindness pays dividends. i hope the soft traits that made other characters continually disparage and underestimate him and his intelligence turn out to be his greatest assets bc i kinda don’t give a shit about a “toughen up it’s the only way everyone else knows better” life lesson for this character

(which like honestly a lot of the rhetoric is dismissive of the fact that persistent goodness in the face of an existence of disparagement takes great strength and that at the end of the day aziraphale has always been able to stand up in his own way)

#good omens #good omens 2 #good omens spoilers #aziraphale #aziraphale IS in fact a dark horse #he is consistently dismissed and underestimated and overlooked bc of how he presents himself! #even crowley does this with him (not in any sort of malicious way its a sense of protectiveness) #(i am not here to get into how aziraphale n crowley treat each other in ways that are unintentionally hurtful id be here forever lmao) #the point is that aziraphale is smart and tbh he knows more about how shitty heavens treatment has been the past few thousand year?? #since he's. he's been the one getting treated badly. that whole time. #anyway theyre both right theyre both wrong and end of the day i just. #i hate the concept of a s3 that equates softness and kindness with being wrong and naive and dumb etc #it does not feel very good omens to me idk man #so i hope that's not where it goes

[reasonsforhope]

"In a first-ever human clinical trial, an mRNA cancer vaccine developed at the University of Florida successfully reprogrammed patients’ immune systems to fiercely attack glioblastoma, the most aggressive and lethal brain tumor.

The results in four adult patients mirrored those in 10 pet dog patients suffering from brain tumors whose owners approved of their participation.

The discovery represents a potential new way to recruit the immune system to fight treatment-resistant cancers using an iteration of mRNA technology and lipid nanoparticles, similar to COVID-19 vaccines, but with two key differences: use of a patient’s own tumor cells to create a personalized vaccine, and a newly engineered complex delivery mechanism within the vaccine.

“Instead of us injecting single particles, we’re injecting clusters of particles that are wrapping around each other like onions,” said senior author Elias Sayour, M.D., Ph.D., a UF Health pediatric oncologist who pioneered the new vaccine, which like other immunotherapies attempts to “educate” the immune system that a tumor is foreign.

“These clusters alert the immune system in a much more profound way than single particles would.”

Among the most impressive findings was how quickly the new method spurred a vigorous immune-system response to reject the tumor, said Sayour, principal investigator at the University’s RNA Engineering Laboratory and McKnight Brain Institute investigator who led the multi-institution research team.

“In less than 48 hours, we could see these tumors shifting from what we refer to as ‘cold’—very few immune cells, very silenced immune response—to ‘hot,’ very active immune response,” he said.

“That was very surprising given how quick this happened, and what that told us is we were able to activate the early part of the immune system very rapidly against these cancers, and that’s critical to unlock the later effects of the immune response,” he explained in a video (below).

Glioblastoma is among the most devastating diagnoses, with median survival around 15 months. Current standard of care involves surgery, radiation and some combination of chemotherapy.

The new report, published May 1 in the journal Cell, is the culmination of seven years of promising studies, starting in preclinical mouse models.

In the cohort of four patients, genetic material called RNA was extracted from each patient’s own surgically removed tumor, and then messenger RNA (mRNA)—the blueprint of what is inside every cell, including tumor cells—was amplified and wrapped in the newly designed high-tech packaging of biocompatible lipid nanoparticles, to make tumor cells “look” like a dangerous virus when reinjected into the bloodstream to prompt an immune-system response.

The vaccine was personalized to each patient with a goal of getting the most out of their unique immune system...

While too early in the trial to assess the clinical effects of the vaccine, the patients either lived disease-free longer than expected or survived longer than expected. The 10 pet dogs lived a median of 4.5 months, compared with a median survival of 30-60 days typical for dogs with the condition.

The next step, with support from the Food and Drug Administration and the CureSearch for Children’s Cancer foundation, will be an expanded Phase I clinical trial to include up to 24 adult and pediatric patients to validate the findings. Once an optimal and safe dose is confirmed, an estimated 25 children would participate in Phase 2."

-via Good News Network, May 11, 2024

-video via University of Florida Health, May 1, 2024

#cw cancer #cw death #cw animal death #medical news and technology #cancer #brain cancer #cancer treatment #tumor #brain tumor #florida #university of florida #medicine #biology #cell biology #mrna #mrna vaccine #vaccines #oncology #good news #hope #Youtube

[curlytsunamiart]

dad's funeral

#across the spiderverse #atsv #spider-man 2099 #miguel o'hara #gabriella o’hara #giving miguel the Came Back Wrong/Dead But Still Walking treatment cus i think its fun #im p happy w this :] hope u enjoy #art #draws

[adeleba]

I love her actually

#hope she doesnt get the skylor treatment #pls pls pls lego let her be relevant for succeeding seasons #ninjago euphrasia #ninjago fanart #dragons rising spoilers #ninjago spoilers #adelebart

[apollos-boyfriend]

the jaiden-roier-cellbit dynamic is so important to me because like. cellbit treats jaiden and roier's relationship with the same level of respect and importance that jaiden treats roier and cellbit's marriage. which may not seem like that big of a thing but like. platonic relationships are often seen as "lesser" than romantic ones, and that your romantic partner should come first before all other bonds in your life. and seeing cellbit treat jaiden and roier's bond and relationship with the same respect that jaiden treats his marriage. as an arospec person it genuinely makes me want to sob

#icarus speaks #THEY ARE THE BLUEPRINT!!!!!!! #THE MOMENT THE EVERYTHING #everything about them in general is so. like some of THE healthiest treatment of aspec relationships ive ever seen #the fact that roier is hypersexual but cellbit is aspec. and there is no conflict with this. sex does not define their relationship #the fact that Everyone acknowledges the importance of roier and jaiden's relationship #they're seen as partners just as much as any of the romantic egg pairings #just. wahhhhhhhhhhhhhh #personally i was struggling a bit with acknowledgement of being aroace. bc a Lot of my friends have been getting into relationships #and i Know that there is a possibility Of me being the lesser of the two options bc romance is so prioritized #but seeing these three gives me so much hope #i hope they know how important they are to the aroace/aroacespectrum community :((

[wi1dshxpe]

gortash sets up a lending library at his estate after seeing durge’s in the bhaal temple. they both know they’re the only people who use them so it turns into a sort of game. durge loves music, so after enver’s last visit a book about viola has appeared in the temple library. enver fancy’s himself a jeweler so it’s only natural a scroll about gem welding would end up in his library. books relating to their schemes, hobbies, pasts, futures, inside jokes and aspirations get passed back in forth. the only extended pause is when a novel about star crossed lovers gets dropped in the bhaal library. it’s weeks before the favor is returned and enver receives a scroll about bhaalist marriage ceremonies. he doesn’t know whether to take it as an advance or a threat, so he accepts it as both.

#dark urge #durgetash #enver gortash #durge #i ​love enver’s boldness to hear durge say ‘nobody whose been in a relationship with me has left alive’ and respond ‘yeah but i’m different’ #he is but not enough to change his fate #they would also be like varying levels of straight forward- at times they’re coming up with entirely new cipher systems for simple messages #100% being way more open they would be normal. gortash would almost never be open about about his time with raphael but he will leave a book #alluding to his treatment when he was at the house of hope #my durge was a cleric of ilmater in their youth and is incredibly ashamed of it by the time they meet gortash. but they do leave him a book #of his teachings with a chapter about meditations they still use to quell their urge #and obviously bhaal hates everything about this. not only is durge besties w his enemy and doing stupid stuff that has nothing to do with #murder they’re being unashamed of things he very much wants them to be ashamed of

[problemcore]

like yea when i was. freaking 16. i saw buccellati as a very parental figure to the passione kids. but im 20 now and im overcome with dread at how the entire world is at his shoulders the entire season. its terrifying. and you reduce him to the mom friend? whatever is actually going on with him is much more intriguing

#i just woke up i hope any of this makes sense #but like bruno is such a heartbreaking character to me. #plus. idk its weird to me now. i have friends who are younger than me in 3-4 . i dont see them as my kids. they're their own people #idk the weird treatment bruno gets in the fandom annoys me #anyway. thanks for reading. im gonna go think about eating breakfast but really im not gonna get out of bed. #chris noises #jjba

[vriskira]

can you believe they kissed during the finale !?!?! (coping)

#total drama reboot #total drama island #total drama #total drama spoilers #td spoilers #td julia #td mk #mkulia #SO hot take i love mullet julia actually. girl just style it a little and itll look good trust me!!! #i wish that she won but wayne is a hilarious winner. love that guy! #mkulia-wise i loveee that they hugged.. theyre so cute #i am so glad that julia didnt get the bald treatment she doesnt deserve it #god forbid women have hobbies (being evil) #anyway heres to mk and julia kissing next season [raises a glass #i liked this season a lot though :) i hope if any more DO come out theyre good too! #enough ramblin outta me im probably gonna draw these 2 some more

[canisalbus]

Currently suffering an ear infection and all I can think is how you said Vasco is prone to them. Does he get miserable and exhausted from the pain or is he more the type to get short tempered and cranky?

.

#I'd say a little bit of both but he tends to get more testy than dejected #because there aren't really any effective treatments for ear infections #he's gotten very careful about cleaning and maintaining his ears and trying to make sure they never stay moist for very long #and that has helped somewhat but he can't avoid them completely which frustrates him greatly #Vasco usually manages to react to adversities with prolonged and stubborn optimism #he generally takes setbacks as a challenge instead of a personal failure #but after his patience and good will finally run out he gets upset #he gets angry but usually in a constructive way and it gives him another boost of energy to attempt to fix things #Machete gets paralyzed by sadness but Vasco rarely does #he just doubles down #answered #werewolfteaparty #Vaschete lore #ear infections are terrible I hope you feel better soon

[ladykyriaa]

I honestly love my pathetically austitic cat-like detectives a lot

#conan i am so sorry I've been neglecting you lately #please wait as my hyperfixation for my other autistic detective die down #i know it's likely impossible but i do hope knh gets the dcmk treatment lom #like. just tons and tkna of episodes #and a bunch of movies too #the apothecary diaries #detective conan

[petr1kov]

hypnos is my favorite hades character but i also think that he was absolutely NOT thought out very well by the developers. he's clearly meant to be a joke character you do not think much about outside of his basic function as the snarky greeter, and who is lazy and annoying enough that seeing the rest of the cast belittle him feels satisfying. but at the same time, after you spend enough time with the game, you see him get progressively characterized as someone who 1) doesn't offer bad advice on purpose to make fun of you as we initially thought, as he really thinks he might help with that and only means to mildly tease you at worst, and 2) actually wants to do the job he was assigned to do but genuinely struggles to perform because he has trouble concentrating on the tasks, a real problem that he eventually learns to accommodate. and on top of that he also loves his family very much even though they barely look his way because he is unserious. so all of these elements converge and make the sillay joke character come across as an unintentionally sad and wronged figure, and his family members come across as assholes, even though they should be sympathetic characters

#like idk. if you want to make a joke character make him a theseus not like a neurodivergent person who gets called a lazy bum lol #i hope hades 2 doesn't repeat that. i don't want his character changed i just don't want the uncomfortably mean treatment by the story #hades game

[strawglicks]

Misty isn't selfish for wanting friendship with toons.

Misty is selfish for her lack of consideration of toons, their feelings, their perspective. She only focuses on herself and how she has been hurt.

She feels hurt by Bessie's actions, claiming "there was no reason" for her to do such a thing. But toons and cogs are at WAR. Bessie didn't see Misty, she saw a COG approaching her and retaliated. She did not see them as an individual, she saw them as the enemy that's been terrorizing and colonizing their land. And rightfully so.

That being said, Misty did not have ill intentions approaching Bessie. Because of this, they feel hurt that she responded in such a violent way. Misty can feel hurt, but they need to understand why toons feel the way they do towards cogs. They are at WAR. And Misty just doesn't seem to realize that.

She feels entitled to play with toons and garner sympathy from them despite their ongoing battle against the cogs.

It's all about "you still tried to hurt me" and "i've done nothing wrong". Misty truly believes she is the victim and thinks she's entitled to sympathy from toons. But she's not.

Misty genuinely wants friendship with toons, which is why she feels so hurt when they reject her, even if they are right in doing so. Much of her dialogue implies she really is oblivious to the gravity of this war and why the toons, obviously, don't want to engage with her:

Misty may want to befriend toons with no bad intentions, but that doesn't erase what the cogs are doing to the toons' land. And the toons are still justified in fighting Misty. She is a cog at the end of the day.

Misty is so focused on her own, personal pain that she is completely disregarding that a WAR is going on. She disregards what the toons endure due to Cogs Inc. and thinks, just because she doesn't personally hate toons, that they owe her friendship.

I think Misty is probably the main reason for the fandom's villainization of toons and woobification of the cogs. But it's not the fault of how she's written, it's the fault of people who feel bad for a character and suddenly think all their morals have to align with that character. Now, they all have to adapt to Misty's way of thinking: that she is an innocent victim who has done nothing and doesn't deserve any of the treatment she's gotten from toons, and that toons are just evil monsters who attack her for no reason.

THIS COULD NOT BE FURTHER FROM THE TRUTH.

You can enjoy a character, like Misty, and feel bad for her. It's obvious there is some real suffering happening here, but it does not justify her view or lack of consideration for others. They are so focused on their own pain that they never think of others. They are so focused on being the victim that no one else can be a victim.

This line of thinking is so flawed, and when a big chunk of fandom REPEATS it, it leads to wild mischaracterization and woobification of. colonizers.

You can like characters who are bad people and disagree with their actions. Misty is not a good person. I think they are suffering, they are hurting, but that cannot be the end of the story. There are others, like the toons, who are suffering and hurting as well. And that should not be erased for the sake of your blorbo. You can still love Misty while condemning her way of thinking. I do myself.

There's the opposite end as well, where people acknowledge this character is not a good person but suddenly think they have to hate the character as a whole because they are morally bad.

Misty Monsoon is very flawed as a person and suffering from her own victim mentality, which hurts others as well. But I love this character. They're fucked up and just want a friend, but they're going to need to be more considerate and aware of their own poor actions if they want to earn that friendship and respect from others. Give and take.

#toontown #toontown corporate clash #ttcc #misty monsoon #rainmaker #my big juicy brain in full effect #having misty thoughts tonight i suppose! #sick and tired of mistys treatment in fandom. i think by far she gets the worst next to chip #misty is not flat evil but they are not good either. #i dont think they wish to be a bad person but they are bc theyre so obsessed with being a victim and getting sympathy #bc they feel its the only way they can be understood and make connections with others #i hope she makes a friend one day. i also hope she massively improves herself before doing any such thing. #get therapy gurl!

[galedekarios]

i've already seen talk on here about larian perhaps planning to update gale's romance with a variety of kissing animations like they already did for some of the companions:

but i also found this while browsing through one of the files (Gale_InPartyEND), which seems to indicate that they may add different variants in addition to that for the kiss animations during the final battle/end of act iii:

kiss basic and kiss chin up remain the same, but the new additions in this context are:

cinematicnodecontext: Kiss WantToKeepYouForever as well as cinematicnodecontext: Kiss CarriedAway

#gale dekarios #gale of waterdeep #gale x tav #tav x gale #baldur's gate 3 #bg3 #otp: you give me hope #otp: a soul that steels my own #ch: gale dekarios #vg: baldur's gate 3 #series: baldur's gate #meta: mybg3 #i'm still kind of /: bc my hopes are below the ground at this point when it comes to larian & their treatment of gale but #i thought i'd share anyway

[fucking-relax]

anger is a pain. treat it like the injury it is:

you feel angry (you feel pain)

stop, take a moment to gather yourself and breathe deeply (stop, take a moment to apply first aid to your wound)

find the root cause of your anger; what brought your anger about and how come? (find what caused your injury; what hurt you, what type of wound?)

what can you do to regain control? try not to fuel the anger with violence; mitigate by being gentle to yourself and others (what can you do to keep you safe from further and future injury? what further treatment do you need? try not to aggravate your wound; be gentle and cautious)

accept you've done all you can, continue to breathe deeply, and find comfort away from anger and violence (accept you have done all you can and continue to take care of yourself)

#source: i am a very angry person (also prone to physical injury) and have tried so many different treatments #the punch pillow and screaming into it is immediate catharsis but i found its not helpful in the long run #but ive been trying this out periodically and again more recently; and it really does work the best for me. so here. hope it helps #relax #reminders