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bethiniancorpuscle · 10 months
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Causes of drug-induced lupus
SHIP
Sulfasalazine & Sulfonamide Hydralazine Isoniazid Procainamide & Phenytoin
This is by no means a definitive list (they are many!) but these are some of the most common causes.
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bethiniancorpuscle · 10 months
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Common ototoxic medications
"FAV Q&A"
Furosemide (and other loop diuretics) Aminoglycosides Vancomycin Quinine Aspirin
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bethiniancorpuscle · 11 months
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Hypokalaemia ECG changes
U have no pot and you have no T but you have a long PR and a long QT
Low potassium causes:
U waves (small deflection immediately after T wave)
Flattened/inverted T waves
Prolonged PR interval
Apparent prolonged QT interval (due to fusion of T and U waves)
Also:
Increased P wave amplitude
Widespread ST depression
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bethiniancorpuscle · 1 year
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Oedema - pitting vs non-pitting
Oedema is swelling due to excess fluids in tissues.
In pitting oedema, pressing on the affected area leaves an indentation (that persists after removing the pressure). In non-pitting oedema, the area feels firm to touch and does not form indentations.
Pitting oedema:
The excess fluid is mainly composed of water
Commonly caused by heart failure, venous insufficiency, or nephrotic syndrome
Non-pitting oedema:
The excess fluid consists of water WITH protein and salts
Usually indicates a condition of the thyroid / lymphatic system
Different types:
Lymphoedema is due to a build-up of lymphatic fluid (e.g. due to a tumour blocking lymphatic flow / after removal of lymph nodes).
Myxoedema occurs in hypothyroidism and often affected the pretibial or periorbital area.
Angioedema is localised swelling of the skin and is usually due to allergic reactions. It typically affects the face, tongue, larynx, abdomen, arms, and legs. When the larynx is affected, it may affect breathing, which is an emergency!
Lipoedema is when fat accumulates in subcutaneous tissues - it usually affects the legs/buttocks and almost exclusively occurs in postpubertal females (not the same as cellulite!)
If patients present with oedema, it's always important to test if it's pitting or non-pitting as this helps to determine the cause and correct treatment!
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bethiniancorpuscle · 1 year
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Causes of Acute Pancreatitis
In the UK and US, the main causes are gallstones and alcohol.
Use the mnemonic 'I GET SMASHED':
Idiopathic
Gallstones
Ethanol
Trauma
Steroids
Mumps / Malignancy
Autoimmune
Scorpion stings
Hypercalcaemia / Hypertriglyceridaemia / Hypothermia
ERCP
Drugs (including azathioprine, mesalazine, bendroflumethiazide, furosemide, steroids, sodium valproate)
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bethiniancorpuscle · 2 years
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Branches of external carotid artery
Some Anatomists Like F*cking, Others Prefer S & M
Superior thyroid artery
Ascending pharyngeal artery
Lingual artery
Facial artery
Occipital artery
Posterior auricular artery
Superficial temporal artery
Maxillary artery
The superior thyroid, ascending pharyngeal, lingual and facial arteries are ANTERIOR branches.
The occipital and posterior auricular arteries are POSTERIOR branches.
The superficial temporal and maxillary arteries are TERMINAL branches.
“Some Anatomists Like F*cking, Others Prefer S & M” 
is a mnemonic my professor just mentioned in class for the branches of the external carotid artery askjvb;askjbv;
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bethiniancorpuscle · 2 years
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Alternatively:
Some Say Money Matters But My Brother Says Big Brains Matter More
Cranial nerves functions mnemonic
Sooo… while studying the cranial nerves and their functions I came by this genius mnemonic and I just had to share it with you guys! :D
cranial nerves and their functions
Some say money matters, but my brother says big boobs make more fun. [m = motoric, s = sensorial/sensitive, b = both]
N. olfactorius (s)
N. opticus (s)
N. oculomotorius (m)
N. trochlearis (m)
N. trigeminus (b)
N. abducens (m)
N. facialis (b)
N. vestibulocochlearis (s)
N. glossopharyngeus (b)
N. vagus (b)
N. accessorius (m)
N. hypoglossus (m)
(fun)
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bethiniancorpuscle · 2 years
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Cranial nerves mnemonic
On, on, on, they travelled and found Voldemort guarding very ancient horcruxes.
Olfactory, optic, oculomotor, trochlear, trigeminal, abducens, facial, vestibulocochlear, glossopharyngeal, vagus, accessory, hypoglossal.
On - Olfactory nerve (CN I)
On - Optic nerve (CN II)
On - Oculomotor nerve (CN III)
They - Trochlear nerve (CN IV)
Travelled - Trigeminal nerve (CN V)
And - Abducens nerve (CN VI)
Found - Facial nerve (CN VII)
Voldermort - Vestibulocochlear nerve (CN VIII)
Guarding - Glossopharyngeal nerve (CN IX)
Very - Vagus nerve (CN X)
Ancient - Accessory nerve (CN XI)
Horcruxes - Hypoglossal nerve (CN XII)
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bethiniancorpuscle · 3 years
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clearance = (urine concentration x urine volume passed over time) / plasma concentration
the only useful thing my prof ever taught me for the renal physiology portion of my physiology course is that clearance is calculated by the equation “pissing under the sun” ( C = UV/P)
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bethiniancorpuscle · 3 years
Photo
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The renin-angiotensin system that helps regulate the constriction of blood vessels and blood pressure.
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bethiniancorpuscle · 3 years
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I don’t know what stage of the semester you’re at right now but let someone in exam period (me) give you some advice on revision: Start early. Early as in NOW. Start now to not end up like me 
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bethiniancorpuscle · 3 years
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Distribution of calcium in the body
Bone calcium (99%)
Ca^2+ and PO4^3+ form hydroxyapatite
Plasma calcium
Diffusible pool
~50% of plasma calcium is free/unbound ionic Ca2+ (physiologically important form)
~10% of plasma calcium is complexed with small molecular weight compounds (citrate, phosphate)
Non-diffusible pool
~40% of plasma calcium is bound to calcium-binding proteins and plasma proteins (albumin)
The body utilises plasma albumin-bound calcium as a circulating reserve
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bethiniancorpuscle · 3 years
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Basic pharmacology of neuromuscular junction
ACh acts on N2 receptors (ligand-gated Na+/K+ receptors)
Block Na+ channels that propagate nerve impulse - local anaesthetics (lidocaine), tetrodotoxin
Inhibit ACh release - tetanus toxin, botulinum toxin
Competitive antagonists - vecuronium
N2 agonists - suxamethonium
Flaccid paralysis
Only cleared by plasma cholinesterase
Reversible anticholinesterases - edrophonium, neostigmine, physostigmine
Block activity of AChE
Diagnose and treat myasthenia gravis and treat glaucoma respectively
Irreversible anticholinesterases - organophosphates (pesticides, nerve gases)
Long-lived flaccid paralysis
Treat with pralidoxime within 10 minutes - cleaves OP-AChE complex
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bethiniancorpuscle · 3 years
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Management of acute MI
Reduce anginal pain
Morphine (+ anti-emetic)
Oxygen
Nitrate
Initiate reperfusion
Anti-platelet (aspirin, clopidogrel)
Thrombolytic (rtPA)
Primary angioplasty (PTCA)
Anticoagulant (heparin)
Protect myocardium
Beta-blocker
ACE inhibitor
Secondary prevention
Aspirin
Lipid-lowering (statin)
Lifestyle
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Helpful mnemonic foe MI treatment.
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bethiniancorpuscle · 3 years
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Carpal bones mnemonic
So Long Till Pinky, Here Comes The Thumb
Scaphoid
Lunate
Triquetrum
Pisiform
Hamate
Capitate
Trapezoid
Trapezium
(going anti-clockwise in this diagram)
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bethiniancorpuscle · 3 years
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Can - Citrate
I - Isocitrate
Keep - α-Ketoglutarate
Selling - Succinyl-CoA
Sex - Succinate
For - Fumarate
Money - Malate
Officer - Oxaloacetate
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oh we are starting my favorite topic in biochemistry the tca cycle because whenever someone’s like :( it’s so hard to remember the intermediates :( i get to tell them about Can I Keep Selling Sex For Money Officer
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