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#is the world's deadliest infectious disease
Me and my friends have a monthly game night, where we play a game or competition, and the loser has to make a donation to a charity of the winners choosing. Next month is gonna be racing Go-Karts, and I've got this in the bag. Are there any TB related charities you would recommend I send my friends to?
YES. The folks leading the charge at expanding treatment access are:
The Stop TB Partnership
MSF
Partners in Health
The Treatment Action Group (which was founded by ACT UP but has now expanded to seek better treatment for people living with TB as well as HIV).
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autumn2may · 11 months
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Johnson & Johnson is currently, like right this minute, trying to extend their patent on the TB drug bedaquiline, keeping it out of generic for another four years. TB killed about 30,000 people last week and is the world's deadliest infectious disease.
If this drug does not go generic now it could affect 6 million people in the next four years (the time it would take the "new" patent to run out). Out of those millions of people who get TB, but can't get bedaquiline, most of them will die. From a PREVENTABLE DISEASE.
Why is this happening? Money. But also, because TB is not an issue in countries like the US. We can afford its $1.50 a pill price. But if you live in a poor country, that's too much money to spend on something you need to take for up to four months.
J&J needs to let this drug go public and do its job in places that can't currently afford it. They need to help people, instead of trying to wring the last few drops of money out of one of their many products, at the cost of human lives. @sizzlingsandwichperfection-blog does a waaaay better job of explaining this than me. Check out the video and the video description for links and ways to help!
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Effing monsters.
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violet-phoenix-nebula · 2 months
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Stigma and illness
"We do not want to reckon with a world that is merely unfair; where some people get sick, not because they did something wrong but because the world is unjust, and insofar as it is just, it's random.
"And so, we tell ourselves we understand, which too often means creating explanations that blame the sufferer. Stigma is a way of saying 'you deserved this to happen', but implied within the stigma is also 'and I don't deserve it, and so I don't need to worry about it happening to me'.
"Stigma can become a kind of double burden for the sick. In addition to living with the physical and psychological challenges of illness there's the additional challenge of having their humanity discounted. Think of the word universally used in English to describe Tuberculosis patients in the 18th and 19th centuries. They were called 'invalids'. They were literally invalid.
"People living with TB today have told me that fighting the disease was hard, but fighting the stigma of their communities was even harder."
...
"Finally, the origin, or perceived origin of a disease also matters. If an illness is seen to be the result of choice it is much more likely to be stigmatized.
"So for instance, people with major depression are often told to just 'choose to be happier' just as those with substance abuse disorders are told to just 'choose to quit drinking'. And some cancers and heart diseases are stigmatized for resulting from purported choice as well.
"Of course, this is not how biology works. Illness has no moral compass, it does not punish the evil and reward the good, it doesn't know about evil and good. But we want life to be a story that makes sense, which is why, for example, it was commonly believed up until the middle of the 20th century that cancer was caused by things like social isolation, parents were actually told their kids got leukemia because they hadn't been adequately loved as infants.
"If a clear cause and effect isn't present, we will invent one, even if it's cruel."
John Green - The Deadliest Infectious Disease of All Time
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cowboyrainy · 1 year
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Tuberculosis in Red Dead Redemption 2
In the beginning of the 20th century, Tuberculosis, also known as consumption, was the second leading cause of death, after Pneumonia. It caused 25% of all deaths, throughout the 1600-1800's Europe. The disease has been around since antiquity and has been discovered in 17,000 year old bison. 
On March 24 1882, German physician and microbiologist Robert Koch, identified and described the bacillus that causes tuberculosis. Today, March 24 is World Tuberculosis Day. Before this discovery, it was believed (commonly in New England) that the disease was caused by vampires or curses. 
During chapter 2, when you collect the depths from Thomas Downes, he'll cough on Arthur, transmitting tuberculosis. Tuberculosis takes a few months or even years to develop and to start showing symptoms, but in poor living and health conditions it can take only but a few weeks for symptoms to show. Active infection occurs more often in people with HIV/AIDS and people who smoke. Today a diagnosis of active TB is based on chest X-rays, microscopic examination and culture of body fluids. Common symptoms include, chronic cough, fever, cough with bloody mucus and weight loss. 
Living in the countryside in 1899 could certainly be unhygienic and put you at risk in many ways, especially when you live outside, like the Van Der Linde gang does. The first sign of Arthur's TB is often considered to be in chapter 4, Shady Belle, when he talks to Herr. Strauss about the depths. If you choose to rob a homestead with Javier in chapter 2, you can hear Arthur cough at the end as well, but since you can complete this Companion Activity before confronting Downes, the only way Arthur could have contracted the disease, is when Thomas Downes breaks up the fight between Arthur and Tommy during "Americans at rest", but it seems unlikely this is a TB cough, due to the short period from exposure to disease (Let me know your opinion :) )
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In chapter 4 after "Revenge is a Dish Best Eaten" Arthur writes in his journal,
"Keep feeling sick but I'm sure it's nothing".
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There are three stages of TB. Exposure, latent, and active disease. Exposure is simply when you are exposed to the bacteria. Latent is when the bacteria is in your body, but you don't feel sick. Latent can then develop into the disease, where you do feel sick. The symptoms can be mild for months. This means Arthur could experience coughs, fevers, night sweats, weight loss and feeling sick or weak, for a while without the bloody coughs and chest pains. I think one reason that his TB develops fast is, like mentioned earlier, poor living conditions, bad hygiene and stress. There was no cure for TB back then and the only thing the doctor can prescribe Arthur is rest and getting somewhere warm and dry, which is the exact opposite of what Arthur's been doing / is going to do.
In 2021, 10.6 million people were diagnosed with turberculosis and around 1.6 million passed away from it. It's the second deadliest infectious disease, after Covid-19.
Trivia
The doctor in rdr2 who treats Arthur, Joseph R. Barnes, is likely named after Joseph K. Barnes, a US physician and surgeon general, who served President Lincoln and Garfield. 
The doctor's appearance looks sort of similar to Robert Koch
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TB was also known as "the romantic disease". Many romanticized the disease, finding the bed written, skinny people beautiful. Some also believed the fevers and toxemia from TB assisted the artistic talent, allegedly helping people to "see life more clearly" and "to act decisively". 
Hello! Thank you if you've read this far. I've been trying to make this blog my primary, but that's not really an option, so i might make my primary a bit more personal, so i can interact more with the community lol. I enjoyed writing this alot and hope someone else found this as interesting as i did. Might make a part 2 to this post, but i'll definitely keep posting "essay" or what ever you wanna call them, because they are great fun to research and write (my autistic brain is happy) . Have a great evening :)
Also! Here are some great videos about TB, the victorian view of illness and fashion, that i think you should watch :)
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Sources:
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just-a-turtleduck · 11 months
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Call To Action Now:
Tell Johnson & Johnson to not renew their patent on bedaquiline
Medical-capitalist eldritch horror, The One With Ten Million Brands, Johnson & Johnson is planning to renew their patent on bedaquiline, a tuberculosis drug, next week, July 18th. Rather than allow the world's deadliest infectious disease which kills mostly the very poor to have treatment options most patients can actually afford, J&J wants to keep a monopoly on what should be a human right.
Tell them that's beyond fucked up and also it violates their credo.
File a report by phone or by typing: https://secure.ethicspoint.com/domain/media/en/gui/28704/report.html (most important please do this! the company is Janssen Pharmaceuticals, and the country is wherever you are) Good reddit thread full of useful templates: https://www.reddit.com/r/nerdfighters/comments/14wv93v/nerdfighter_call_to_action/
Keep the pressure on their social media: Twitter: https://twitter.com/JNJNews and https://twitter.com/JNJGlobalHealth Facebook: https://www.facebook.com/jnj/ Instagram: https://www.instagram.com/jnj/?hl=en
Further: If you're contacting them maybe even bring up that they promised to help end TB by 2030! Price comparison between J&J* and generics *Not sure if this reduced price is even still happening or if that was just for the pandemic! Will update once I can clarify. I called! It took ~20 minutes and the person on the line was very nice.
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meret118 · 4 months
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But the ability of a corporation to allow a potentially lifesaving vaccine to languish lays bare the distressing reality of public health vaccine creation. With limited resources, governments have long seen no other option but to team with Big Pharma to develop vaccines for global scourges. But after the governments pump taxpayer money and resources into the efforts, the companies get control of the products, locking up ownership and prioritizing their own gain.
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Arw you really the author John Green? The same person who wrote The Fault in Our Stars and Looking for Alaska?
Yes, but I published one of those books 19 (?!?!?!) years ago and the other 12 (!?!?!?!?) years ago. What have I been up to since then?
My brother Hank and I started Good.store, which delivers high-quality socks, coffee, and soap to your home and donates 100% of its profit to charity. Through good store, we've raised over $7,500,000 to support efforts to radically reduce maternal mortality in Sierra Leone, where as recently as 2019, one in seventeen women could expect to die in pregnancy or childbirth.
(In fact, technically I am here on tumblr as an unpaid intern for the awesome coffee club, which you should really sign up for if you like ethically sourced coffee that tastes delicious and doesn't enrich billionaires.)
I wrote the novel Turtles All the Way Down and then had a little existential crisis and wrote a nonfiction book called The Anthropocene Reviewed, the latter of which is my first book for adults and my first attempt to write as myself.
I helped produce made a movie adaptation (streaming now on Max!) of Turtles all the Way Down.
I helped raise my kids and supported my spouse as she wrote her book You Are An Artist and created a PBS show about art called The Art Assignment.
I ran the educational media company Complexly and the merch company dftba.com while my brother had cancer.
I bought around 2% of a fourth-tier English football team called AFC Wimbledon. Wimbledon are different from most football clubs because they are owned by their fans, each of whom gets one vote in the club's leadership regardless of how much money they put into the club.
I became obsessed with tuberculosis, the world's deadliest infectious disease (it will kill over a million people this year despite being curable), and how TB both exemplifies and reinforces human-built structures of injustice, which is the subject of a book I'm writing that will come out next year.
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trooperwrites · 9 months
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Itsuwari no Marigold
Quality: 8/10
Enjoyment: 8/10
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Genre: Romance/Historical
Synopsis:
A young lady named Kasumi Hana living in early 20th century has her brother die from the world's deadliest infectious disease, TB. Dealing with grief, she believes that her brother's penpal, a lady by the name of Urushizawa Lily, was using him; if true, Hana intends to kill Lily and to commit suicide. However, she ends up finding out that Lily is both blind and someone who deeply cared for Hana's brother. For the sake of her brother and this girl, she resolves to become the impostor
take her brother's place.
Reviews
I believe the text was originally supposed to be published as a oneshot and I think the first chapter works with its ending being incredibly bittersweet. However, the manga ended up getting a continuation and despite its short length(5 chapters) has brought into questions about survivors guilt, dealing with loss and perhaps even questions about identity(specifically relating to gender). I thought what was present was thematically interesting and well done and I'm excited for more chapters to be available to read.
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quotesfrommyreading · 11 months
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The plague swept Europe 700 years ago, killing a third of the population. It was called the Black Death, possibly for dark patches caused by bleeding under the skin.
It killed millions in China and Hong Kong in the late 1800s before scientists began associating the illness with rats and eliminating rodent populations.
The plague comes in three forms. If a person gets bitten by an infected flea, they'd most likely develop bubonic plague, named for the painful lumps, or "buboes," where the bacteria multiply. The bacteria can also get into the bloodstream, causing septicemic (or blood poisoning) plague, and can also spread to the lungs, causing pneumonic plague. The World Health Organization considers this variant to be one of the deadliest infectious diseases because it is highly contagious – spread by coughing — and the fatality rate is 100 percent if untreated.
Early symptoms of the plague can mimic the flu — including lethargy and swelling or stiffness in joints and lymph nodes. If someone begins exhibiting these symptoms after coming into contact with rodents or with pets in regions where the plague exists among animal populations, they should seek medical care immediately, Markman says.
  —  Bubonic Plague Strikes In Mongolia: Why Is It Still A Threat?
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livingsociety · 2 months
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Combating Tuberculosis: The Power of Public Awareness
Written by Abubakar Sheudeen Tuberculosis (TB) has plagued humanity for centuries, remaining one of the world’s deadliest infectious diseases. Despite significant progress in medical science, TB continues to pose an important global health threat, particularly in low- and middle-income countries, according to the World Bank. However, amidst the challenges lies a potent solution: public…
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ramtracking · 2 months
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The world's deadliest infectious disease is on the rise in the UK [ United Kingdom ]
The world’s deadliest infectious disease is on the rise in the UK [News Summary] A blood test could identify millions of people who unknowingly spread tuberculosis, scientists have said. More than a million people a year… Cases of Tuberculosis has surged in parts of the UK and could destruct the nervous system, bones and glands – here are some of the key… Nearly a dozen suspected cases of a…
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publicadclerk · 6 months
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Who Is Involved in the Global Response to HIV and AIDS?
There are many nongovernmental organizations (NGOs), foundations, and other key partners engaged in the global response to HIV and AIDS. Below are some of the largest NGOs working to prevent new HIV infections and scale up access to treatment and related health services for people with HIV.
The Global Fund
The Global FundExit Disclaimer is a partnership designed to accelerate the end of AIDS, tuberculosis, and malaria as epidemics. An international organization founded in 2002, the Global Fund mobilizes and invests more than US$4 billion a year to fight the deadliest infectious diseases, challenge the injustice that fuels them, and strengthens health systems in more than 100 countries. The Fund works in partnership with governments, civil society, technical agencies, the private sector, and people affected by the diseases to challenge barriers and embrace innovation..The Global Fund raises funds on a three-year cycle, bringing longer term predictability in the fight against AIDS, TB and malaria and in reinforcing resilient and sustainable systems for health. Governments, the private sector and nongovernmental organizations pledge funds to support our mission. The Global Fund provides 30% of all international financing for HIV programs and has invested $24.2 billion in programs to prevent and treat HIV/AIDS as of June 2022. Since 2020, the Global Fund has also stepped up to support countries to mitigate the impact of COVID-19 on the HIV response.
International AIDS Society
Founded in 1988, the International AIDS SocietyExit Disclaimer (IAS) is the world’s largest association of HIV professionals, with members from more than 170 countries. IAS convenes, educates and advocates for a world in which HIV no longer presents a threat to public health and individual well-being. After the emergence of HIV and AIDS, concerned scientists created the IAS to bring together experts from across the world and disciplines to promote a concerted HIV response. Today, the IAS and its members unite scientists, policy makers and activists to galvanize the scientific response, build global solidarity and enhance human dignity for all those living with and affected by HIV. The IAS also hosts the world’s most prestigious HIV conferences: the International AIDS Conference, the IAS Conference on HIV Science and the HIV Research for Prevention Conference. For more information, visit www.iasociety.orgExit Disclaimer.
UNAIDS
The Joint United Nations Programme on HIV/AIDSExit Disclaimer (UNAIDS) is an international organization that leads the global effort to end AIDS as a public health threat by 2030 as part of the Sustainable Development GoalsExit Disclaimer. The organization provides strategic direction, advocacy, coordination, and technical support to help catalyze and connect leadership from governments, the private sector, and communities to deliver life-saving HIV services. It generates strategic information and analysis that increases the understanding of the state of the HIV epidemic and progress made at the local, national, regional, and global levels. It also leads the world’s most extensive data collection on HIV epidemiology, program coverage, and finance and publishes the most authoritative and up-to-date information on the global HIV epidemic. UNAIDS unites the efforts of 11 UN organizationsExit Disclaimer—UNHCR, UNICEF, WFP, UNDP, UNFPA, UNODC, UN Women, ILO, UNESCO, WHO and the World Bank—and works closely with global and national partners to achieve its mission.
World Health Organization
The World Health OrganizationExit Disclaimer (WHO) is a United Nations agency that connects nations, partners and people to promote health, keep the world safe, and serve the vulnerable so that all individuals can attain the highest level of health. Within WHO, the Department of Global HIV, Hepatitis and Sexually Transmitted Infections ProgrammesExit Disclaimer(WHO/HHS) leads the development and implementation of the global health sector strategy on the elimination of these three diseases as public health threats. WHO/HHS develops global evidenced-based guidelines and provides technical support to address public health gaps and challenges common to the three diseases. Visit WHO’s HIV/AIDS health topic pageExit Disclaimer for more country-specific information, data, and more.
KFF
The Kaiser Family FoundationExit Disclaimer (KFF) is a nonprofit organization focusing on national health issues, as well as the U.S. role in global health policy. KFF’s global health policy workExit Disclaimer focuses on providing the latest data and information on the U.S. role in global health to offer a comprehensive picture of the U.S. global health policy landscape, focusing on key issues facing policymakers, journalists, non-governmental organizations, and others working in the global health arena. In the area of HIV policy, KFF conducts research and analysis on current HIV-related policy issues, with a focus on the U.S. government’s response to the epidemic domestically and around the world. It also maintains a dashboardExit Disclaimer monitoring the status of PEPFAR countries’ progress toward achieving global HIV targets.
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katslefty · 7 months
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thxnews · 7 months
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Transforming Global Health: Climate-Resilient Initiatives Unveiled
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  A Pioneering Partnership for Global Health
In a groundbreaking move, the World Bank and the Global Fund to Fight AIDS, Tuberculosis, and Malaria announced today the signing of a new Memorandum of Understanding (MoU). This collaborative effort outlines a strategic plan to fortify health systems in the Global South, aiming to bolster efficiency, effectiveness, and sustainability in the face of climate change.   Tackling Climate-Induced Health Challenges Head-On Rising temperatures, shifting disease patterns, and the looming threat of pandemics prompted World Bank President Ajay Banga to emphasize the urgency of a comprehensive response. "We cannot make adequate progress on public health without responding aggressively to the challenges posed by climate change," Banga stated, underscoring the need for a united front.  
Prioritizing the Most Vulnerable
The focus of this partnership extends to climate and health priorities, specifically targeting malaria, HIV/AIDS, and tuberculosis (TB). By strengthening health systems and improving access to primary healthcare services, particularly for vulnerable populations, the two organizations aim to make a significant impact on global health outcomes.   The Human Toll of Climate Change The World Bank estimates that by 2030, 132 million people may be pushed into extreme poverty due to climate change. Alarmingly, one-third of this number will result from climate-related health risks, disproportionately affecting the poorest and most vulnerable communities.  
Building Resilient Health Systems
"To stand a chance at achieving the targets of ending AIDS, TB, and malaria, we must redouble our efforts to fight these diseases," asserted Peter Sands, Executive Director of the Global Fund. Sands stressed the necessity of investing in health systems capable of withstanding the effects of climate change, particularly as malaria serves as an early indicator of climate impact on health.   Advocating for Financial Support Crucially, the two organizations will advocate for increased financing for health, aiming to build the country's capacity for more efficient and sustainable financing across health systems. The goal is to maximize the use of limited domestic and international health resources through improved public finance management.  
Strengthening Health Supply Chains
Another key focus area is the regional production and procurement of health supplies, including drugs and medical devices. The organizations aim to enhance access to essential health supplies, ensuring preparedness and resilience in health systems. Efforts will be directed towards localizing health supply chains, and supporting sustainable manufacturing in Africa and low- and middle-income countries.   Collaborative Success Stories Since 2017, the World Bank and the Global Fund have collaborated on various successful projects. From a loan buydown in India to innovative funding linked to improved TB detection in Indonesia, and increased primary healthcare services in Haiti, these initiatives have showcased the potential for positive change.  
About the Global Fund and the World Bank Group
In the fight against HIV, TB, and malaria, the Global Fund is a global partnership that raises and invests over US$5 billion annually. Since 2002, this alliance has saved an astounding 59 million lives, uniting leaders, communities, and the private sector to tackle the world's deadliest infectious diseases. On a parallel front, the World Bank Group envisions a world free of poverty on a livable planet. Operating in over 100 countries, the World Bank Group provides financing, advice, and innovative solutions to confront urgent global development challenges. Comprising entities such as the World Bank, IFC, MIGA, and ICSID, it stands as one of the largest sources of funding and knowledge for developing countries. Together, these organizations forge a path toward a healthier, safer, and more equitable future for all.   Sources: THX News & The World Bank. Read the full article
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meret118 · 8 months
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A vaccine against tuberculosis, the world’s deadliest infectious disease, has never been closer to reality, with the potential to save millions of lives. But its development slowed after its corporate owner focused on more profitable vaccines.
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