hi more drug question
I have been told many many times that using ecstasy will basically fry your seratonin receptors so that you will never be able to feel happy again unless you are using the drug. I am assuming now that this is false but I am curious now as to how false. Is it something that CAN happen if you take too much at once or too often, or is this just random Drug Scary misinformation
Also also since wellbutrin is not an SSRI does LSD work when you are on it or does it also cancel it out
lol that's kind of an extreme version of what I usually hear! you're right that basically the answer here is no. this comes from a couple different things. first is MDMA induced serotonin toxicity, and 2nd is something called "serotonin syndrome" which is a real thing that can happen, but it's really really hard to get like this. prepare for a very long answer lmfaooo
MDMA induced serotonin toxicity occurs when you take too high doses too frequently. MDMA IS slightly neurotoxic, but so are many prescription drugs so don't let that word freak you out too much! basically MDMA works by dumping large amounts of serotonin into your brain, hence why it's the happy/love drug lol. if you take too much too often, your brain will straight up run out of serotonin. obviously that's bad! it's not as simple as "never feeling happy again" but you will essentially have depression for a bit because of lack of serotonin (on its own, low serotonin levels following modest MDMA use is not damaging and resolves within a few days) but the real problem is that if you are on MDMA with depleted serotonin, your brain will continue releasing dopamine which will attach to the serotonin receptors and damage them. this is what can cause long term depression symptoms, the damaged serotonin receptors. ultimately your brain will heal this on its own unless for some reason I guess you keep taking it a lot (which would have no effect. when you take too much MDMA your brain just runs out of serotonin to dump so like. it just won't work lol)?? it can also be treated with the supplement NAC, which I would recommend taking any time you use MDMA because of this!
to sum up MDMA toxicity: it can happen but only if you're misusing it! it's generally recommended that you dont do much more than 1 dose every 3 months or so to make sure your brain has time to reset. research interactions with anything else you're using (prescription or not), take some NAC in the weeks following a dose, drink a lot of water, keep your body temperature regular because that can worsen it, and take some antioxidants like alpha lipoic acid and grape seed oil during/immediately after taking MDMA - it's when you come down that your brain is delicate and could use the protection. also this may sound counterintuitive but weed also has antioxidant properties, so smoking it as you come down helps a lot. also if you DO have MDMA toxicity taking more MDMA will not help u feel happy unfortunately it will just make it worse lol, your brain only has so much serotonin to give
now serotonin syndrome can happen with the misuse of any drug that works on serotonin including MAOIs, SSRIs, and SNRIs, usually by taking a VERY large dose (but some people are just extremely sensitive). it usually takes care of itself eventually, but the amount of time it takes and stuff is kinda hard to pin down bc it's REALLY misunderstood and tends to be overly self diagnosed. again this is like super super hard to do. you would have to take a MASSIVE dose or mix it with other serotonin affecting drugs (ESPECIALLY MAOIs. DO NOT MIX MDMA WITH MAOI ANTI DEPRESSANTS). like 5 times the normal dose at least probably (partner is currently trying to find some literature on it so he'll add that in the replies if he finds anything interesting). it will cause things like heightened anxiety and body temperature and can cause kidney problems or seizures if it's like really bad and untreated. but you'd feel REALLY bad before it got to that point, so in general like, if you take any type of drug and feel extremely bad after go to the doctor lol. mostly this will also just heal itself; your brain is pretty resilient! again usually if this does happen it's very minor. cases bad enough to require hospitalization are exceedingly rare
to give you an example of what these can look like, I have a friend who was given about 3-4 times a regular dose by a fucking piece of shit asshole she knows and, this part is crucial, it was mixed with a very large amount of alcohol AND acid (which can slightly increase the neurotoxicity. normally not a huge issue but becomes one in circumstances like this), AND coke; like she was blackout drunk and while not on a lot of acid or coke, this is just too many things to have in your body and brain at one time. the mixture of such a large amount different drugs caused her what I'm guessing was a mild case of both of these things at once. she experienced slightly worsened depression for about 6 months after, and actually had a mild stutter for almost a year. I made sure she took some NAC and other things that aid brain healing, and she didn't try molly again for a long time to be super sure she didn't overload her brain before it was ready. this is a pretty extreme case, and even with that she has fully recovered thankfully. do NOT EVER do drugs with someone you don't trust with your life. DO NOT EVER do drugs in doses you have not confirmed for yourself to be safe and DO NOT EVER mix drugs without finding out if it's safe!!! just as a small aside though: usually taking molly and acid at the same time is perfectly safe. in fact it's called a candy flip and I HIGHLY recommend it because it's fucking awesome. again, just make sure you are taking safe doses in a safe environment
OKAY now finally your specific question about Wellbutrin: I actually take Wellbutrin so I can answer this one from personal experience! Wellbutrin should not alter the effects of LSD in any way HOWEVER! both of these drugs lower your seizure threshold! I'm on the max dose of Wellbutrin (which is the max dose BECAUSE of seizure risk) so when I plan to drop acid I usually either skip my dose entirely that day or only take half depending on how much acid I'm planning to take. because of the way Wellbutrin works, this shouldn't cause you any problems as far as that goes. for me, not taking my Wellbutrin for a day mainly has the effect of making me more fatigued, and acid counteracts that really well by making me feel very awake/aware. if you don't want to skip or halve your dose though you can also take things that will RAISE your seizure threshold. so like I sometimes will smoke hemp because CBD actually will help with that. the risk here isn't huge either way especially if you have no history of seizures, but again if it's something you're concerned about you should be just fine skipping or lowering your dose for the day. acid usually lasts about 12 hours too so i personally don't even care about skipping the Wellbutrin that much because it basically does the same thing for me. I did take my full Wellbutrin dose the last couple times I've done acid though because I was taking a very small amount of acid (about half a tab)
in summation lol sort of TLDR I generally would recommend MDMA for recreational use because the risks of damage are low and it's safe if you are safe about it. and it's honestly just a really fun one! the only negative effect I've ever felt is some emotional and physical fatigue the following day, and this is largely because of how emotional and energetic you are on it. I just make sure to have the next day off to lay around and listen to music :)
taking it with a partner or loved one will give you an especially beautiful experience, as MDMA has been proven to facilitate extremely open emotional conversations. in fact, when MDMA was first synthesized it's primary use was in psychotherapy! research was shut down during the war on drugs, but in recent studies it's demonstrated amazing abilities to treat and even straight up CURE disorders like PTSD. for a personal anecdote, my partner actually completely fucking cured his alcoholism on a combo of MDMA and whippets (nitrous oxide) lmfao. like dude straight up went from getting black out drunk multiple nights a week to drinking nothing for the past year and a half without any other treatment program. LSD has been proven to have similar incredible results with treating and curing things like depression, anxiety, PTSD and addiction and is also a very fun and very safe one.
sorry to reiterate for the billionth time lol but it's important: these drugs are safe and fun if you make sure they're safe and fun! do your research and never use in an unfamiliar environment with people you wouldn't trust in an emergency! also I know this sounds like a lot, but remember I'm giving you like the absolute safest possible practices and emphasizing sort of over cautiousness because I think it's always better to be too safe. I've taken molly without nac and I've taken kinda big doses a little closer together than I should have without any problems. there's a bit of flexibility to these guidelines, but it's always better to think of them as being rigid so you don't end up too far in the other direction. like I've said it's really really hard to do actual damage that would last more than like a day or 2 max. most of the time you'll just be sleepy the next day from all the dancing so it's nice to do it on a day 1 of a weekend. also it only lasts like a couple of hours lol so it's not your whole day or anything!
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V9C4
Finally here after several hours of a dnd session zero, so this whiplash is going to be interesting
Post Ep: not as infuriating as the last episode but still missteps at pretty much every turn. At the very least we can say there’s been character “progression”
God Ruby’s voice is so damn bad I thought it was a literal child calling for a cat. Why does she sound more mature at 15 than 17?
Did we really need a close up of the cat piecing itself back together? We already know it can do wacky things with its ugly gradient body, so why the emphasis here? I doubt it’s foreshadowing for a permanent bisection
“Nothing we’ve tried has gotten us any further.” Ruby. Darling. Babe. You’ve tried walking to the tree. Nothing else. It’s not the cat’s fault you can’t think of something else besides Scooby Doo hijinks with the looping sections
What the hell is Yang now? She hasn’t been fun or quippy since Beacon but now (and that one spot in V8) she’s suddenly Joss Whedon with a dash of Hulk rage? And I can’t recall Weiss ever having these kinds of facial expressions. Judgmental commentary, sure, but this feels like she’s 3 seconds away from saying something into the camera like this is the Office
“Just because [the cat] doesn’t want to go back to the tree doesn’t mean we can’t lure them there.” That’s... a curious choice of words. Why “lure?” You lure someone into a trap or an ambush, not ask someone to be a guide. Why wouldn’t Blake use the obvious direction of “we can make a deal with the cat because they’re curious and want information we have.” You can’t really call someone a hero when their instinct is deception of a potential ally who’s already saved their asses for no real reason
Are they going to be losing the cat the whole damn episode? Is that going to be the running gag? I fucking hope not. Ruby’s voice is absolutely obnoxious this episode
She’s talking to the cat like he’s a literal toddler. And it’s acting like a toddler with an ipad. Someone put me down like Old Yeller please
Which of these idiots thought lampshading was a good idea? Like, congrats! You recognize the flaws in the story you wrote! How are you going to fix them 10 years too late? You can’t wink, wink, nudge your way out of shitty writing that you so desperately defended and clung to despite all the people giving actual constructive criticism
Why are all of them so tired of the questions? Surely, each of them have something they’d be ecstatic to talk about at length? Ruby with the progression of weapon development, Weiss with her plans to improve the SDC, Blake with other stories she’s read or how the White Fang came and fell, Yang with stories about Ruby when she was younger. There’s so many possibilities when you have a genuinely curious audience, yet they went the lazy route of “har, har, no one cares about anything” again
Was that bridge made of legos?
Okay, this is the second time the roles of acres have been mentioned. Exactly what does that mean? Do these roles serve a central purpose? The tree seems to be at the center of Wonderland, so are the acres serving the tree in some way? Is harmony throughout the different factions pivotal in keeping Wonderland in wonder instead of despair? What could this possibly mean for any themes or character arcs? It doesn’t seem like the areas thus far have resonated with any of the team, and they left behind Penny’s halo sword, the only thing that’s been even somewhat emotionally compelling, so I’m struggling to understand why Wonderland is set up like this
Love how literally nobody asks the obvious question of “are you okay?” All we get is Yang’s “Rubes?” (has she ever called Ruby that before? I can’t recall) and Blake’s logical deflection and Weiss whining yet again. You’d think for a season that cut away from the bloated cast to focus on the main characters they would, I don’t know, focus on the main character
This is the least Little has talked the entire season. Please keep the cat around more so this shithead will shut the fuck up. Also, Little deadass pointed to where the cat went and y’all don’t immediately follow? Are you trying to get lost?
Okay. Not gonna lie. The caterpillar’s design is dope as shit. The triple eyes in that gorgeous green. The pointy mouth that moves like a skeleton’s jaw. The two-toned wings. The antennae and little spikes. The collar and vest. That ~voice~ Fucking A+
The only thing I’m side-eyeing is the accessories. Hopefully I’m wrong - I’ll be the first to admit I’m not well versed in Indigenous cultures - but the coloring is very reminiscent of turquoise which was an incredibly significant mineral to Southwestern Native American tribes, most commonly associated with Navajo, and Caterpillar’s jewelry designs reflect this as well. My quick google search for this specific design mostly ends up being “hippie aesthetic” which does take inspiration from Indigenous aesthetics, so I can’t really say for certain which one crwby looked at for the design. Given the Medicine Man trope and the herbal smoking in the OP, I’m not holding out much hope
“Growgurt” sounds so damn gross please never say it again
They are really hammering this “who/what are you” thing directly into your eardrums aint they? I’m not entirely sure how this answer affects a recipe, but go off I guess
Also, note how Caterpillar gets just the bit exasperated and Yang’s immediately in a fighting stance. The others are afraid, for some cocksmith of a reason - all homeboy did was grumble, what y’all scared of? Did y’all suddenly develop RSD? - but this bitch at half a foot is ready to throw down
Caterpillar is speaking philosophy 101 and these idiots are acting like he’s speaking ancient greek. I hope he poisons the lot of them
“This is how a king winds up a prince.” Does that imply that the prince was genuinely the king that played Alyx but he’s somehow reverted back to a toddler? That raises way too many questions I have no care to even ponder
This far in and we have no idea who or what Caterpillar was to Alyx. Not even a whispered expo-dump, which would be stupid easy given that most of them are tiny. Yet Blake, upon seeing the smoking, is like “we gotta dip” which so par for the course in every episode thus far. This better not be crwby’s attempt at an anti-drug message or I swear I’m gonna toss a fridge into space
Oh christ on toast the Beacon outfits don’t deserve this slander
“You could just be human or just a cat.” Once again, weird phrasing. Like, yeah, it’s clarified that it’s about trying to bring peace between humans and faunus, but why wouldn’t you phrase it in a way that sticks closer to that sentiment rather than acting like she has the Yamato and can carve out what she doesn’t like?
What would it even mean to Blake to “just be a cat?” Would that mean living in Menagerie forever with no worries about humans? Would she turn into an actual cat? She just has fucking cat ears man, this is so overblown
Wow, these “I know who I am” speeches suck ass. They’re so vague and InSpIrAtIoNaL I’m wondering if this is supposed to be a mature cartoon or a reading of those posters they put up in school halls of cats in trees with the quote “hang in there!”
“I’m the granddaughter of a hero” bitch who? Who is this mysterious hero? If someone doesn’t know or watch the Remnant expo-dump series, they don’t know who you’re talking about Weiss! You can’t bring up something in the main story if the context is shoved in a spinoff! Also, “daughter of a villain.” Babe, your father was a clown at best and a business major at worst. Villain is not a title he deserves
“I will not be defined by my name because I will be the one to define it.” Uhhhhh exactly where in this redefinition is compensation for the lives stolen by your family company? Have you thought of that, Miss Heiress? When your name has that big of an impact, I don’t think you get to be the sole decider. Also, you have siblings who might want a say in it too
Still pissed that the whole “Missing Summer” arc was shoved onto Ruby, who was what? 2? 3 years old when she left? Ruby talks to her gravestone, sure, but as for memories or stories, she hasn’t had a single one. This entire thing falls flat because there was 0 buildup
“You’re supposed to be helping others find their way, but you’ve lost your own.” WHAT WHAT WHAT THE FUCK. Jesus on a toaster strudel can you not villainize every single person who slightly questions uwu precious Ruby? He literally helped the other 3 cement themselves, why doesn’t that count? Sure, it was against their will and all, but these girls clearly need some goddamn help if they can’t answer a basic question like “what is a huntress?”
There are so many questions about those last 20 seconds that I don’t even know what to do with them. Let’s just sum it up with “what the fuck”
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Every time you make a post about yourself I’m reminded of how fucking similar we are and it’s always something new and it’s so weird. Like I vent my issues through creative works but sometimes I’ll write it and it’ll take me months to realize that’s a problem I even have. I have several projects about the character (basically my self fucking insert let’s be real) being unfeeling at least out worldly or their powers or whatever they’ve got causes them to have no emotions or they were raised that they literally cannot show emotions (🤨 that’s a real project I’ve had for years. Idk how we are the same person) and therefore don’t. But one that I have in particular has a scene where the MC is watching his sister cry in their mom’s arms and he’s just thinking “how could she let herself be so vulnerable? Isn’t she embarrassed?” And later he realizes he was also somewhat jealous bc while they share a mom, she never lets him be anything but a punching bag and he has to be emotionless. This is totally not based on a real experience whatsoever and I have a normal relationship with my family *eye twitches*. This is so many words to say that I get that a lot. Even when I’m struggling I’d have my mom be like “you’re such an asshole why can’t you just snap yourself out of it” or thinking she’s being lighthearted by going “this is why all your friends leave you” and I’m like ah. I’m never saying anything ever again. Also ah, I come across like an ass when I’m just some guy in my head and in places where I’m relaxed and have the energy to be how I actually am/want to be (close friends, online, etc.). Basically this is so fucking long to say that I get the same shit that you do and it’s garbage, but like everyone else has said I don’t think you’re unfeeling. I get a sense of like camaraderie? Like “same hat” kind of thing, I get what you mean when you say literally anything because I get it? If you were so cold hearted, I think that wouldn’t be a thing because you’d just be nothing, there wouldn’t be anything to relate to? But yeah, I’m shaking your hand. I genuinely don’t know how we are one person split in two, it sounds like I’m just making shit up but I stg I have not lied in your inbox as of yet - 🫐
Also our periods are synced up. I don’t even know you. Genuinely, literally, with my whole soul: what the fuck - 🫐
blueberry anon im experimenting with the paranormal to contact you in increasingly concerning ways can you hear me. i saved this ask for a bit after you sent it just bc it really surprised me the comfort i got just from like. someone not only acknowledging it all but also being like 'we're in this together' type thing. like everything you've ever sent me has me nodding like yeah this guy gets it fr fr, and when a lot of times that's in response to posts i was nervous to make? it means a lot x
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