#Extension | Explore Tumblr Posts and Blogs

amber-tortoiseshell · 2 months

Note

I don't understand amber. How does it work? What does it do? How is it different from wide band/golden/ect.? Please explain

Ohoho, you invited me to talk about my favourite gene!

Amber is the mutation of the MC1R (melanocortin 1 receptor) gene. Recessive mutations here are associated with red and yellow color varieties in lots of species: rabbits, horses, mice and humans, to mention a few examples.

So what does this gene do? Replaces the black pigment with red. That's the gist of it.

The regular orange color of cats is a different gene, but they have similar molecular backgrounds: red and amber are both phaeomelanin-based colors. Phaeomelanin is one of the two most important pigment types in mammals, together with eumelanin. Eumelanin is responsible for black and brown colors, phaeomelanin is for reds and yellows. Black, chocolate and cinnamon are the traditional eumelanin-based cat colors.

Eumelanin-based tabbies have both eumelanin and phaeomelanin in their fur, the alternation of these two pigments make the agouti hairs banded: the lighter bands have only phaeomelanin. Phaeomelanin-based colors have only or overwhelmingly phaeomelanin in both the lighter and darker bands (the difference is probably the amount of pigments).

Now wide band does something different: it extends the lighter bands, so the coloration becomes less eumelanin-dominated (when there's eumelanin present). Thus, yellow cat.

The first figure shows basically the comparison of the hairs of a black and a red or amber tabby, the second is how golden hairs look like:

That's the difference between amber and golden. One of them changes the color of the agouti bands, the other changes their size.

Here's a red, an amber and a golden cat for comparison:

The amber tabby in the middle has darker orange tabby pattern, the black golden cat still has a black tailtip, black feet, sometimes even some black markings on the face.

The coolest thing about amber is that unlike red and golden, the kittens born with a lot of eumelanin, and they gradually lose it as they mature. Like this:

Nowaja (Galaxy vom Ritterclan), amber smoke with white

#ask and answer #i hope it's clearer now #extension #amber

1K notes · View notes

felinefractious · 6 months

Text

Hazel vom Aller-Leine-Tal

🐱 Norwegian Forest Cat

📸 vom Aller-Leine-Tal

🎨 Amber Tortoiseshell [Extension Gene: Amber]

#photo #norwegian forest cat #NFO #black tortoiseshell #extension #amber tortoiseshell #ft #age progression #b: vom aller leine tal

923 notes · View notes

arc-hus · 4 months

Text

Museo Castelvecchio, Verona, Italy - Carlo Scarpa

-

#Carlo Scarpa #architecture #design #building #modern architecture #modernist architecture #old and new #extension #historical #old building #museum #museum design #courtyard #concrete #stone #stairs #beautiful design #italy #italian architecture

324 notes · View notes

koneko-dreams · 3 months

Text

Marriage

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Priest: @sillyfatherof3 and @koneko-dreams , have you come here to enter into marriage without coercion, freely and wholeheartedly?

#Marriage thing #Sh*t it's happening #Extension #I got permission bro-#And yes I tagged myself #twst rp

44 notes · View notes

sawthemusical · 4 months

Text

If you didn't get the chance to see us #SAWRIGHTHROUGH this past winter and fall, not to fear. We'll be cutting limbs loose for a good while longer! #SAWTHEMUSICAL is officially extending it's run at The AMT Theater until June! Amidst this, our #NationalTour will be launching. More info can be found about our extension and national tour on our home page. Link in our bio. Thank you for all your support. Without you...our work would not have been possible

#saw the musical #saw #off broadway #national tour #extension #new york #parody #horror #saw franchise #adam stanheight #lawrence gordon #chainshipping #lgbtq #lgbtq theater

56 notes · View notes

neweresth · 1 month

Text

Insight.

#onefield #leadtobelieve #isitreal #powerofthought #idea #intention #digitalart #illustration #neweresth #extension

21 notes · View notes

germanpostwarmodern · 1 year

Text

Extension (1930) of the Henke House in Essen, Germany, by Mies van der Rohe

#1930s #house #extension #modernism #modernist #architecture #germany #architektur #essen #mies van der rohe

131 notes · View notes

bernardreneguillot · 1 year

Text

Work in progress/ Atelier exterieur

73 notes · View notes

doomspaniels · 1 year

Text

little dressage spaniel

#tristan #cocker spaniel #dogblr #golly he's pretty #flexion #extension #somehow also very up-and-down #bob bob bobbing along #camera gifts #prance puppy prance #spanielish walk

67 notes · View notes

rationalistarchitecture · 5 months

Text

Neil Middleton Architects

Cluny Gardens House Extension, Edinburgh, 2023

The existing house had a small extension to the rear but due to the significant change in level there was no connection between the garden and the interior space.

The main idea for the project was to drop the dining/living space down towards a new external terrace. This created a direct and meaningful connection between the garden and an enlarged family living space.

Upstairs a new family bathroom and a generous additional double bedroom replace a small single bedroom.

Externally, the extension is in white roughcast render, with a textured finish - this creates a distinct but related character to the existing house. The brick basecourse aligns with the ground floor level of the existing building providing a hint of the level change internally. The roof is pitched to tie in with the geometry of the existing building whilst avoiding the existing rooflights.

Photography by Tom Manley

#architecture #rationalist architecture #extension #house #house design #scotland #scottish architecture

16 notes · View notes

amber-tortoiseshell · 1 year

Text

Description of the genes under the break

Beware the long post!

Genetics guide

Dilute modifier (): This unidentified gene further lightens the color of a diluted cat, the coloration becomes more brownish.

dominant allele: Dm - (variant)

recessive allele: dm - (wild type)

blue, lilac, fawn -> caramel

cream -> apricot

I put here a cat in all three diluted colors to compare them with the caramel tabby. It's hard to spot the differences, isn't it?

Since this is a dilute modifier, the D allele covers it, and we can only see its effect on cats with dd genotype.

It can be found only in a few breeds: orientals (including related breeds) and burmese. To our current knowledge, of course.

Extension (melanocortin 1 receptor, MC1R): This gene replaces eumelanin with pheomelanin resulting in a yellowish or reddish furred cat. The change often happens gradually during the first years of the cat's life.

dominant allele: E - eumelanin remains, black adjacent cat (wild type)

recessive alleles: e, er, ec - pheomelanin takes over, yellow/red adjacent cat: amber, russet or serdolik (variant)

All three recessive variants are new mutations found recently in different breeds: the color amber in the 1990s in norwegian forest cats, the color russet in 2007 in burmese, and the color carnelian or serdolik in 2018 in kurilian bobtails (at least that's the first mention). We don't know anything about their interactions, or their effects on cats outside of their respective breeds.

The gene only effects eumelanin, so the O allele is epistatic over the it. However, because of the properties of the overpowering pheomelanin, every e allele is epistatic over agouti, so the tabby patterns will show up on aa cats as well.

Wide band (serine peptidase, CORIN): This hypothetic gene makes the yellow bands on the agouti hairs wider, resulting in a lighter, yellowish pelt.

dominant allele: Wb - eumelanin on normal sized area, darker cat (wild type)

recessive alleles: wbSIB, wbeSIB, wbBRI - eumelanin on reduced area, lighter cat (variant)

Ohhh, citizens of tumblr, we're really in it now. So. In the moment, we have, I believe, three mutations found on this gene: the sunshine (wbSIB) and extreme sunshine (wbeSIB) in the siberian breed, and the copper (wbBRI) in british cats. (I only show the sunshine and the copper here.) The novelty of these mutations means that the breeders still often call them simply golden instead of the new names, so it's difficult to find reliable data. Further complicating the situation, most likely both breeds have more wide band gene(s) beyond CORIN, and especially the copper cat above is the result of the combination of several wb genes.

Karpati (?): This unidentified gene makes the extremeties (face, ears, legs, tail) white kinda like a reverse colorpoint cat, and causes a roaning effect: scatters white hairs everywhere on the body.

dominant allele: K - whited extremities, karpati cat (variant)

recessive alleles: k - normal pigmant production, full colored cat (wild type)

Karpati seems to show intermediate inheritance with significantly more white on a homozygous then a heterozygote cat. This gene is studied for a very short time, and mostly on heterozygotes since they are much more common. The cats appearence changes during their life and also with the seasons: they born very similar to a fever coated kitten but with white ears, then to the end of their first year they almost completely lose all white (at least the heterozygous cats - the homozygotes become darker but still keep strange white patterns like the cat in the header, who the same cat but older as the above depicted KK one), then slowly gain it back as they age.

The karpati mutation is present in the stray cat population in middle-east Europe (including Hungary where I live, wahoo! and indeed, I can regularly see one or two karpaties in facebook adoptions groups and such). It's also introduced to some established breeds (LaPerm, Sphynx) and the creation of its own breed also began under the Transylvanian name.

#cats #cat genetics #genetics #macska #polls #tournament poll #dilute modifier #extension #wide band #siberian wide band #karpati #introductions #cat color gene tournament

85 notes · View notes

felinefractious · 1 month

Text