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ablasphemyofpoets · 8 months

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Vaccine PSA for people in the US

It’s fall and that means time for vaccines! There are two everyone who can should get and an additional one for people over 60.

1- The new Covid booster! This was approved today, 9/13, and distribution will begin this week. Depending on where you are, it will be available the end of this week or beginning next week. You can get this booster if it’s been 2 months since your last one. It offers the best protection against the most current variants.

If you have insurance, the booster should be covered. If you don’t, the government is covering them until 2024. https://www.vaccines.gov/ will help you find where to get a free shot. Covid boosters will be available at health departments, pharmacies, mobile clinics, and doctors offices.

Why should you get one: the current circulating strains are very different from the previous ones with many mutations. Your previous boosters won’t protect against them very well. Healthy people are still getting very sick from Covid and hospitalizations and deaths are still high and will only rise going into winter. Long Covid is also a possibility. Even if you only get a mild case, you could infect someone else who won’t be so lucky. Getting a booster will protect you and your friends and family.

2- The flu shot- You probably do this every year. The flu shot is pretty standard but it’s also important especially with Covid because you can get both sicknesses at the same time. The flu also kills about 35,000 people per year in the US and while most of those people have an underlying conditions, many don’t. Even if you don’t die from the flu, it’s not very much fun and quick shot can help prevent you from getting it or lessen the severity. Getting your flu shot will also help protect the people around you who can’t get the shot because of allergies through herd immunity. It will also help protect the elderly and immunocompromised. Even if you don’t have an underlying condition that could make the flu serious for you, you probably know someone who does.

The flu shot is free at most county health departments and insurance will cover it as well. If you are in college, many colleges offer free shots for students and staff.

You can also get the Covid booster and the flu shot at the same time!

The best time to get the flu shot is between the end of September and the end of October. Getting it then helps ensure that your protection will last through most of the winter and the worst of flu season. It is not recommended to get it sooner than that because your protection will wear off over time.

3- RSV. This vaccine is new this year! However, it isn’t available or recommended to everyone. Right now, it is for pregnant people to protect their baby and for those over 60. Even if you aren’t in that demographic, you might know someone who is and they might not know about it. Talk to the people you care about and encourage them to get this vaccine.

Note that you should not get the RSV vaccine at the same time as your Covid or flu shot. It is recommended to wait 1-2 weeks in between to make sure you get the proper protection.

Insurances should cover this vaccine but make sure to check first! It can be quite expensive if not covered by insurance. Some places may offer it for free or reduced cost to vulnerable groups.

What is RSV? RSV is a mild respiratory virus and is just like a cold for most people. However, young babies and people over 60 are much more likely to develop severe illness and be hospitalized or die from it.

Here are some sources if you want to learn more about any of the information in this post.

#vaccine #medical #important #psa #get vaccinated #sick #covid isn't over #covid 19 #covid vaccine #long covid #covid pandemic #covid19 #flu #flu shot #rsvvaccine #rsv #rsvshot

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misshappilyfading · 4 months

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reflections + hopes vii

still here but in EST finally : ) referencing last year's post

again, i did a LOT this year. the whole year was kinda weird but not at all in a bad way. im happy with my 2023

good things:

i kept my exercise promise! and i found new fun ways to work out which really helped things : )

was my fandom regression to SJ a good thing? idk but it really jumpstarted my korean study and listening skills. and it was fun

watched a lot of really good kdramas and knowing brothers eps

my parents got to visit me in japan! they saw my apartment and stuff which i didn't think was gonna be possible

i went to south korea!! the trip was really fun and i had lots of good food

morning royal bread + smoothie + sausage and eggs :) or ikea meatballs + eggs

i saw twice in tokyo!

lawson ebi-kun

spring anime season was amazing. the shojo revival was wonderful

my kyushu (+hiroshima) trip!! i saw so much and ate so much

my trips to chubu, nagoya, and nagano were also fun. got to wrap up my last few bucket list trips in japan

went to 2 real cultural festivals

took a birthday trip to okinawa, sanrio puroland, and decorated a cute tiny cake!

okinawa food is good as fuck man

finally went to karaoke in japan

started grad school with full funding at a super prestigious school

actually having so much fun in grad school!! and i've made new friends easy peasy!

went on my first date (liked someone who liked me back for once)

finished my first semester with all A's : )

i learned 35 kpop dances this year! and they were all super fun

came home for christmas and made some kick ass food

i didn't eat great all year but i did try + i exercised so i'll give myself 0.75 points. i guess i technically have savings?? haven't taken N1 yet and I didn't do one song a month...so 7.75/11 goals completed? which is better good imo

2024:

(even more seriously this time) eat better this year

keep exercising consistently and try a new routine

maintain perfect dental hygiene (brush and floss the right way, 2x a day)

put down the bottle! limit myself to 1-2 drinks per week

get back to budgeting and making strict grocery/expense lists

take N1 (and pass)

study abroad in South Korea

start returning "i love you"s to my parents

finish grad school with my 4.0 intact

learn at least 3 kpop dances each month

get rid of my student loans

continue staying safe from covid, rsv, flu!

#and that's that!#these become more fun as i get older and am less depressed #like wow i have actually stuff to do #i have a life!#hoping these good vibes continue into 2024 and my...mid 20s :0

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meeedeee · 10 months

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If you are struggling with poor #AirQuality, whether #smoke from #fires or #COVID, you can make your own CORSI #AirFilter. But not all of us are handy, so here are ones that you can purchase

"Can now order CR boxes with quiet fans. Less expensive and outperform HEPAs...good for smoke, allergens, airborne viruses including influenza, SARS-2, RSV, and others"

https://www.cleanairkits.com/collections/shop-all?s=09

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itisiives · 1 year

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I had quite a few medical scares.

I had constant chest and back pain and a racing heart rate that I was for sure were signs of a heart attack, so I made visit after visit to the ER and clinic, only to learn that I had costochondritis and an elevated amount of cholesterol and low amount of potassium, but an otherwise healthy heart. I was just experiencing more of that good ol' anxiety.

Then, I had cramps in my sides and extreme dizziness, so that was another rush to the ER, where I had tested positive for a UTI. They put me on antibiotics that I was unfamiliar with, sparking a bout of paranoia that I may be allergic to this medication because, as far as I'm aware, I haven't been truly tested for allergies. Not only that, but I've learned that there are a plethora of side effects that could be fatal, such as contracting C. Difficile, developing pulmonary fibrosis or permanent nerve damage or a failing liver. In addition to that, I'm terrified of developing another UTI or not fully recovering from this one, leading to sepsis.

And then I learn that globally, humanity may face yet another pandemic: a not-quite-Last of Us fungal pathogen, Candida auris. And we're not even done with the tridemic of the flu, RSV, and COVID!

COVID, yet another fear I have as I return to work from my extended break, in which patrons coming in are coming in maskless and we don't know which ones are vaccinated and which aren't, and which are clear of COVID and which are carrying it and spreading it around without a fucking care in the world.

I am going to die.

Not at the ripe old age of 80, after a long life full of joys and sorrows, achievements accomplished on the mountains of failures and mistakes, where I can watch my final sunset on the porch and take a breath of relief that I am finally done with living. I am going to die before I even turn 30, where life supposedly truly begin.

I am going to die because I live in a world full of selfish idiots, many of them MAGA or MAGA-adjacent, who rally against mandates because they foolishly believe that public health is an infringement of rights (but are perfectly fine with forcing people to have babies they can't have or don't want, even though abortions don't affect them.) or believe in that frou-frou New Age natural immunity and essential oils bullshit. I am going to die because mandates are dropping all over the states and I live among antivax idiots who let COVID spread and mutate even beyond the capabilities of vaccines (facilitating a need for boosters every goddamn half-year) and are willing to let children drop dead in schools of this and many other preventable diseases as long as they own da libs. I've been vaccinated, and was infected with thankfully mild COVID symptoms, and have even boosted, but I still fear developing Long COVID or a reinfection, especially after my recent UTI diagnosis and the fears of my antibiotics' side effects.

I live among self-centered and blind fools who don't care about the extreme climate change that will worsen global diseases (like the Candida auris) and leave a destroyed world for future generations (future generations that they are trying to force people with unwanted pregnancies to birth), so long as they can make a weekly paycheck at their gas and coal jobs and, once again, put a stop to "liberal agendas".

This is a world where we have or are developing technology that can make vaccines to prevent infection from many of the world's pathogens, but we had hardly reached an nth of that potential because greedily high profits from all of the industries, not just pharmaceutical, have to be protected, even at the expense of poorer people's health and very lives.

I am going to die because I live alone with only a pet to comfort me, and I am going to die tired and broken and confused.

#spilled thoughts #personal essay #vent post #trauma vent

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rayarmat · 2 years

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Bee Venom Against Diabetes, Asthma, Cancer and COVID-19?

Bee venom is a biotoxin which can cause severe allergic reactions in some people due to the excessive stress response of the immune system. At the same time, bee venom and its main polypeptide component melttin, are linked, similar to expensive chemotherapeutic agents, to variety of cancer management effects including apoptosis, necrosis, cytotoxicity and mitochondrial disruption, inhibition of angiogenesis, metastasis and invasion of cancer cells, including prostate, breast, lung, liver and bladder.

Bee venom therapy, has also been used in traditional medicine to treat diseases such as arthritis, diabetes, rheumatism, pain, tumors, and skin diseases.

Melittin, is a non-selective cytolytic peptide which binds to negatively charged phospholipid bilayers membrane surfaces and therefore, physically and chemically disrupts all prokaryotic and eukaryotic cell membranes including our red blood cells, hence its biotoxic effect.

New research published by an international team of scientists proposes the use of bee venom as a potential adjuvant against COVID-19. The authors indicate the potential of bee venom to disrupt the protective membrane envelopes or the replication of a wide variety of enveloped and non-enveloped viruses, including Human Immunodeficiency Virus (HIV), Coxsackievirus, Enterovirus, Influenza A Viruses, Human Immunodeficiency Virus (HIV), H1N1, Herpes Simplex Virus (HSV), Junín Virus (JV), Respiratory Syncytial Virus (RSV), Vesicular Stomatitis Virus (VSV) and Tobacco Mosaic Virus (TMV).

The authors point out that bee venom, in low doses and controlled dilute concentrations, triggers a range of anti-inflammatory responses, and have been deployed for management of diabetes, rheumatoid arthritis, heart disease, obesity, asthma, skin diseases, and central nervous system-associated diseases, such as Alzheimer's disease, Parkinson's disease, and sclerosis. At low doses, bee venom can suppress inflammatory cytokines such as interleukin-6 (IL-6), IL-8, interferon-γ (IFN-γ), and tumor necrosis factor-α (TNF-α).

Separately, another research group in India has also suggested the use of micro-dosed melittin-in-surfactant compounds or coconut oil-melittin nanoemulsions as a nasal spray to prevent against ARDS (Acute Respiratory Distress Syndrome) associated with SARS-CoV-2.

Data published in sciencedirect.com indicates that beekeepers living in the epicenter of the SARS-CoV-2 virus did not contract the virus, and neither did a group of patients receiving apitherapy. A total of 5115 beekeepers were surveyed from February 23 to March 8, 2020, including 723 in Wuhan, the outbreak epicentre of Hubei. None of these beekeepers developed symptoms associated with COVID-19, and their health was totally normal.

The co-authors pointed out that “It reminds us the story of the discovery of cowpox and the eventual victory of humans over this disease.”

There is little known about the interactions of bee venom and melittin with SARS-COV-2 infection. In vitro antiviral assay results post melittin-treatments have shown significant decrease in the SARS-CoV-2 viral loads compared to the untreated group. Animal injection studies show melittin wrapped in nanoparticles increases the number of immune cells such as CD8+ T cells, CD4+ T cells, NK cells, and monocytes. In humans, these cells all play an important role in control of SARS-CoV-2 infection.

Other studies show that bee venom can activate T regulatory cells that control runaway inflammation (Cytokine storms).

youtube

One big caveat to the observation in Wuhan is the tolerance developed in those beekeepers to bee stings: “These people have one thing in common: they develop a tolerance to bee sting,” wrote lead author Wei Yang, an oncologist from China and two associates. In other words, bee venom is not immunogenic to certain people who are raised in cohabitation with, or live near bee colonies. For the rest of people who are in big polluted cities and away from feral bee colonies, and therefore, unsure of their reaction to bee venom, I would advise caution.

Related paper:

#bee #COVID19

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classyfoxdestiny · 3 years

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FDA-approved gout drug could show promise in fighting COVID-19

A gout drug approved by the U.S. Food and Drug Administration (FDA) could reportedly show promise in fighting the coronavirus.

According to a recent study from the University of Georgia (UGA) published in Nature’s Scientific Reports, probenecid has potent antiviral properties that make the oral medication a prime candidate to combat not only SARS-CoV-2 infection but other common and deadly respiratory viruses.

COVID-19 HAS KILLED AROUND AS MANY AMERICANS AS THE 1918-19 FLU

The school noted that probenecid is primarily used to treat gout and has been on the market for more than 40 years, with minimal side effects to patients.

“There’s really nothing out there to safely fight these viruses,” Ralph Tripp, lead author of the study and GRA Eminent Scholar of Vaccine and Therapeutic Studies in UGA’s College of Veterinary Medicine, said in a statement. “This antiviral works for all RNA respiratory viruses we tested, including SARS-CoV-2. RSV, coronavirus and flu all circulate in the same season. Bottom line is you can potentially reduce infection and disease using this one oral drug.”

To be effective, probenecid blocks viral replication, preventing it from infecting an individual’s cells.

In testing, UGA said, the medication works both as a prophylactic prior to virus exposure and as a post-exposure treatment, noting the drug has also proven effective in fighting RSV in vitro.

TrippBio used animal models – hamsters – against SARS-Cov-2 and the flu.

“Although the drug would primarily be used after a person is positive for the virus, the prophylactic findings mean people with known exposures could also potentially take the drug to prevent getting sick,” the university said.

FDA PANEL ENDORSES PFIZER’S COVID-19 VACCINE BOOSTER FOR PEOPLE 65 AND OLDER, HIGH-RISK PATIENTS

To date, the COVID-19 pandemic has killed more than 676,000 Americans, according to the data from Johns Hopkins University.

In addition, 42,292,350 confirmed cases have been reported in the U.S. thus far.

Treatment for those severely ill due to COVID-19 is still limited.

UGA notes that the current go-to treatments include remdesivir and monoclonal antibodies. Only remdesivir has received federal approval for the treatment of COVID-19.

“These treatments have seen some effectiveness against SARS-CoV-2, but they’re very expensive and very hard to come by,” Tripp said. “In reality, there are only a handful of options that can actually be used because of the cost, restricted IV usage, and lack of access. That’s not very useful to the world.”

UGA compared repurposing remdesivir to fight COVID-19 with potentially repurposing probenecid with a prescribed pill and suggested that probenecid could possibly also increase the effectiveness of other treatments.

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Researchers are investigating what dosage of probenecid could be most impactful in combattng viruses and TrippBio is reportedly set to begin clinical trials of the drug by the end of the year.

Side effects of probenecid include nausea, dizziness, vomiting and headaches, according to The Atlanta Journal-Constitution.

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swarajya7793 · 3 years

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How COVID-19 Impacted on Molecular Diagnostics in Healthcare Industry ?

COVID-19 Impact on Molecular Diagnostics in Healthcare Industry

The COVID-19 pandemic has affected the molecular diagnostics market positively on a global level. The persistence of COVID-19 for a longer period has increased the need for molecular diagnostic tools and instruments to diagnose certain diseases, especially the COVID-19 virus. During the COVID-19 pandemic, manufacturers expect a boost in their market as demand for instruments such as PCR or real-time PCR or COVID-19 test kits has increased with the spread of coronavirus. The increasing demand for molecular diagnostics instruments, tools, kits, software, and services will propel the growth of the global molecular diagnostics market. The COVID-19 has led to the lockdown worldwide, which has tremendously impacted the molecular diagnostics market.

Moreover, the coronavirus is life-threatening, and proper diagnosis on time has become important and molecular diagnostics are the solution for that. COVID-19 is a contagious disease and can be spread easily via droplet particles. The necessity for the diagnosis of positive cases has increased to ensure prompt care of the affected individual and to curb the further spread of coronavirus in the population. RT-PCR is an important molecular diagnostic instrument that is used to detect SARS-CoV-2. Hence, with the ongoing COVID-19 pandemic, the demand for molecular diagnostics has increased tremendously and will boost the growth of the market.

AFTERMATH OF COVID-19 AND GOVERNMENT INITIATIVES FOR GROWTH OF THE MARKET

The COVID-19 outbreak has become a global public health emergency, and it has increased the need for accurate and rapid molecular diagnostic technology for screening, treatment, isolation, prevention, and control of COVID-19. The demand for primary diagnostic tools that detect antigens or antibodies specific to SARS-CoV-2 infection via nucleic acid detection technique or rapid diagnostic tests has increased. Moreover, the cases for COVID-19 are increasing tremendously, increasing the demand for molecular diagnostics tools, services, and instruments to provide proper diagnosis and treatment to control the spread of COVID-19. Hence, the professionals are also looking out for the technologies, tools, and kits to detect the diseases and treat patients on time. Even after the COVID-19, the molecular diagnostics market will propel globally to treat and diagnose different diseases like cancers efficiently and on time. With the COVID-19 pandemic, the government also gets little concerned about introducing molecular diagnostics tools in the market.

For instance,

· In August 2020, According to Spandidos Publications, China National Medical Products Administration opened a special channel to approve new pharmaceuticals for urgent clinical needs and 18 nucleic acid detection kits, one sequencing-related equipment, 11 protein detection kits, and software have been approved until April 23, 2020.

· In March 2020, Cepheid received Emergency Use Authorization (EUA) from the U.S. Food & drug Administration (FDA) for their product-Xpert Xpress SARS-CoV-2, a molecular diagnostic test for detection of SARS-CoV virus.

The COVID-19 pandemic has increased the demand for molecular diagnostics to provide proper screening, diagnosis, and treatments for COVID-19.

IMPACT ON DEMAND

With the ongoing pandemic, the demand for molecular diagnostics products and services has increased. The cases for COVID-19 patients are rapidly increasing, creating a great opportunity for the molecular diagnostics market. To stop the spread of COVID-19 and to treat positive patients, proper diagnosis and treatment are required, which can only be possible through molecular diagnostics instruments, services, software, and others. People suffering from other diseases apart from COVID-19, such as cancer, also require proper medical attention and treatment, increasing the demand for the molecular diagnostics market worldwide. PCR and RT-PCR are some of the important diagnostic instruments required to diagnose positive patients properly. Rising people suffering from COVID-19 and increasing demand for molecular diagnostics enable manufacturers to properly launch proper kits and instruments to detect COVID-19.

For instance,

· In March 2021, Quidel Corporation expanded its manufacturing facility in California, U.S., to produce Quidel’s popular QuickVue line of products, which helps detect and diagnose COVID-19 infection.

· In May 2021, Beckman Coulter, Inc. launched a fully automated and quantitative COVID-19 IgG Test to assess the number of antibodies of COVID-19.

· In December 2020, Beckman Coulter, Inc., launched the Access SARS-CoV-2 Antigen assay, a cost-effective and high-throughput COVID-19 test, which is ideal for mass testing in the U.S.

· In April 2020, Bio-Rad Laboratories, Inc. launched a serology assay to detect COVID-19 antibodies.

· In June 2020, Cepheid announced the development of the next-generation test of the Four-in-One combination test for SARS-CoV-2, Flu A, Flu B, and RSV. The XpertSource: Company Website, Press Releases, DBMR Analysis Xpress SARS-CoV-2/Flu/RSV helps in the detection of 4 viruses from a single patient sample.

· In September 2020, QIAGEN launched QIAreach SARS-CoV-2 Antigen Test, which analysis the antigen in less than 15 minutes. This new product launch helps in detecting the COVID-19 virus at a much faster rate.

The rising number of launches for COVID-19 test kits and molecular diagnostics tools by manufacturers to offer rapid and accurate analysis of the COVID-19 virus will boost the global molecular diagnostics market growth. Moreover, the demand for molecular diagnostics will be increasing even after COVID-19 to cure and diagnose other diseases.

IMPACT ON SUPPLY CHAIN

The supply chain for molecular diagnostic tools has decreased initially during COVID-19 as the governmental body has posed restrictions on movements, imports, and export of goods. But with the growing demand and increasing need to diagnose COVID-19 patients and other patients suffering from different diseases such as cancer or infectious diseases, the supply of instruments has increased. With the restriction on movements, the manufacturers could not make instruments and couldn’t export or import the molecular diagnostics tools from one country to another because of restrictions on goods. But after the lockdown is lifted, the supply chain for molecular diagnostics has taken a toll as the need for diagnosis has increased, which ultimately increased the supply for molecular diagnostics instruments, tools, kits, and others.

IMPACT ON PRICE

The molecular diagnostics instruments are costly as the reagents' needs for it or any other supplies are on the higher side, making the total service costlier. Also, the research and manufacturing of molecular diagnostics products are tedious and time-consuming, making the instrument expensive. Furthermore, instruments, laboratory supervision, utility, space, and supervision ads up to additional prices. The high cost of instrumentation and services for molecular diagnostics makes it hard to afford for lower-class families, restricting the market's growth. Moreover, during a pandemic, the demand for molecular diagnostics products, especially PCR machines, real-time PCR (qPCR) machines, and others, has increased and with rising demand, the prices for services and instruments has also increased.

STRATEGIC INITIATIVES BY MANUFACTURERS

The rising demand for molecular diagnostics tools, services, instruments and others has led the manufacturers to launch new products in the market for different diseases even during COVID-19 time. Additionally, manufacturers partner with other companies to launch new technology or products or acquire them or merge with them. All these strategies opted by manufacturers is to gain more market share in the market.

· In March 2021, Hologic, Inc. acquired diagenode, a molecular diagnostic assay and epigenetics product manufacturer for USD 159 million.

· In April 2021, QIAGEN partnered with DiaSorin to launch LIAISON LymeDetect Assay for early diagnosis of Lyme Borreliois. It is based on QantiFERON technology.

· In June 2020, Myriad Genetics, Inc. launched AMPLIFY Technology to increase the performance of Prequel NIPS Kit, which is used in prenatal screening.

· In March 2021, F. Hoffmann-La Roche Ltd signed a merger agreement with GenMark Diagnostics, Inc. To access their novel technology to test for a broad range of pathogen from single patient sample.

· In October 2020, Meridian Bioscience launched a complete solution to support liquid biopsy cancer diagnostics, as it allows direct RNA and DNA detection from liquid biopsy samples such as whole blood.

The increasing number of launches, mergers, acquisitions, and partnerships by manufacturers to develop new molecular diagnostics products, services, or technologies to fulfill the rising demand for molecular diagnostics will boost the market's growth.

THE RISING COVID-19 CASES ARE LEADING THE MOLECULAR DIAGNOSTICS MARKET.

The rising number of COVID-19 patients is increasing the need for molecular diagnostics instruments and services for proper diagnosis and treatment, which will boost market growth in the future. Also, molecular diagnostics are the primary diagnostic tools for rapid and accurate diagnosis and for the screening, isolation, treatment, prevention, and control of COVID‑19. The rise in prevalence of COVID-19 cases is the main factor boosting the growth of the market.

For instance,

· In July 2021, According to World meters, there are 30,619,932 cases of COVID-19 in India.

· In July 2021, According to World Health Organisation (WHO), there are 183,700,343 confirmed cases of COVID-19 patients worldwide.

· In January 2020, According to World Health Organisation (WHO), there are 33,378,240 confirmed cases in the U.S.

The rise in COVID-19 cases and its proper diagnosis increases the demand for molecular diagnostics.

CONCLUSION

COVID-19 pandemic has affected the molecular diagnostics market positively. The demand for molecular diagnostics instruments, especially detection kits, PCR and RT-PCR has increased to detect the COVID-19 in patients properly. This factor will boost the growth of the market. During the COVID-19 outbreak, the government also took initiatives to approve diagnostics kits that are urgent and are needed to curb the pandemic situation. The rising need for the proper, rapid, and accurate diagnosis will propel market growth globally. Moreover, the incidence of COVID-19 has increased tremendously, which will propel market growth. Therefore, the need for molecular diagnostics to offer proper treatment to the patient has increased, and the market is expected to boost post-COVID-19 as well.

#Molecular Diagnostics Market #Molecular Diagnostics Market Analysis #Molecular Diagnostics Market Size #Molecular Diagnostics Market Forcast #Molecular Diagnostics Market Future Innovation

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