#immunosenescence
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Improving Medical Records
It seems to me….
“The digital world has been in a separate orbit from our medical cocoon, and it’s time the boundaries be taken down.” ~ Eric Topol[1].
Progress in the medical field has, in general, been considerable slower than in other fields though more is invested in medical research. In some ways, there has been relatively little progress since the days of primitive shamans and medicine…
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#AI#ailment#Artificial Intelligence#biology#biomedical#Continuity of Care Document#Department of Veterans Affairs#Dmitri Mendeleev#FDA#Food and Drug Administration#Health Information Technology for Economic and Clinical Health (HITECH) Act#health record#Immunosenescence#medical#medical practitioner#Medical Records#Medical Research#medical science#medical system#medical treatment#patient#physician#RNA#therapeutic#Therapy#VA#Veteran&039;s Administration
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Understanding Complement-mediated Nervous System aging in Order to Develop Neurodegenerative Therapeutics
Maturing is becoming one of the greatest weights to the created world, predominantly because of it being connected to various sicknesses from neurodegenerative problems like Alzheimer's infection to malignant growth. It includes the dysregulation of essentially every organic interaction known, influencing each organ and tissue by particular components, the idea of which is simply now starting to be genuinely perceived. This is additionally valid for cognitive decline, which is viewed as one of the most ordinary indications of advanced age. This isn't is business as usual, given the still restricted information with respect to how recollections and considerations are put away and used by the Central Nervous System (CNS). A possible clue, nonetheless, is the new revelation that the supplement framework assumes a part in synaptic pruning, which is fundamental for deleting superfluous recollections. This is especially charming given that the supplement framework is a part of the inborn insusceptible framework which has been recorded as being overactive with maturing. This audit will accordingly cover what is at present had some significant awareness of the connection between the safe framework and maturing and what the progressions in the resistant framework with age mean for the mind with an end goal to coordinate further exploration. This subject has not been evaluated overall, which is the reason this paper expects to sum up the data on this point while likewise explaining on the holes in research to foster possible treatments for neurodegeneration and immunosenescence.
See the Link here: journalibrr.com
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The cytokine storm and chronic inflammation of long COVID drive the debilitating symptoms we experience. There is evidence that the damage a single Covid infection does to the immune system is equivalent to 10 years of physiological aging. Your biological age and physiological age are different things. Your physiological age is determined by the state of your immune system. The process of physiological aging of the immune system, is called immunosenescence. One of the consequences of this is autoimmune diseases. As you age, your native T cells naturally decrease. The immune system dysregulation we are seeing with SARS2 is T cell exhaustion, depletion of native T cells.
This chronic inflammatory process is implicated in the pathogenesis of numerous age-related disorders, including cardiovascular diseases, neurodegenerative conditions, metabolic and autoimmune disorders.
See how this connects to what we are seeing in Long Covid?
See the full thread here.
COVID ages our immune system by 10 years. Let that sink in.
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NASA, SpaceX Launch Climate Science Research, More to Space Station A SpaceX Dragon resupply spacecraft carrying more than 5,800 pounds of science experiments, crew supplies, and other cargo is on its way to the International Space Station after launching at 8:44 p.m. EDT Thursday from NASA’s Kennedy Space Center in Florida. The spacecraft launched on a Falcon 9 rocket from Launch Pad 39A at Kennedy for the company’s 25th commercial resupply services mission for NASA. It is scheduled to autonomously dock at the space station about 11:20 a.m. Saturday, July 16, and remain there for about a month. Coverage of arrival will begin at 10 a.m. on NASA Television, the agency’s website, and the NASA app. Among the science experiments Dragon is delivering to the space station are: Mapping Earth’s Dust The Earth Surface Mineral Dust Source Investigation (EMIT), developed by NASA’s Jet Propulsion Laboratory in Southern California, employs NASA imaging spectroscopy technology to measure the mineral composition of dust in Earth's arid regions. Mineral dust blown into the air can travel significant distances and affect Earth’s climate, weather, vegetation, and more. For example, dust containing dark minerals that absorb sunlight can warm an area, while light-colored mineral dust can cool it. Blowing dust also affects air quality, surface conditions such as rate of snow melt, and phytoplankton health in the ocean. The investigation collects images for one year to generate maps of the mineral composition in the regions on Earth that produce dust. Such mapping could advance our understanding of the effects of mineral dust on human populations now and in the future. Speedier Immune System Aging Aging is associated with changes in the immune response known as immunosenescence. Microgravity causes changes in human immune cells that resemble this condition, but happen faster than the actual process of aging on Earth. The Immunosenescence investigation, sponsored the by International Space Station U.S. National Laboratory, uses tissue chips to study how microgravity affects immune function during flight and whether immune cells recover post-flight. Tissue chips are small devices that contain human cells in a 3D structure, allowing scientists to test how those cells respond to stresses, drugs, and genetic changes. Soil in Space On Earth, complex communities of microorganisms carry out key functions in soil, including cycling of carbon and other nutrients and supporting plant growth. Dynamics of Microbiomes in Space sponsored by NASA’s Division of Biological and Physical Sciences, examines how microgravity affects metabolic interactions in communities of soil microbes. This research focuses on microbe communities that decompose chitin, a natural carbon polymer on Earth. High School Student Weather Study BeaverCube is an education mission that will teach high school students aerospace science by having them design a CubeSat. BeaverCube will host one visible and two infrared imagers to measure cloud properties, ocean surface temperatures, and ocean color to study Earth’s climate and weather systems. It also will demonstrate an application for the use of shape memory alloy technology via an in-orbit calibration technique. Genes, No Cells Cell-free technology is a platform for producing protein without specialized equipment of living cells that need to be cultured. Genes in Space-9, sponsored by the National Lab, demonstrates cell-free production of protein in microgravity and evaluates two cell-free biosensors that can detect specific target molecules. This technology could provide a simple, portable, and low-cost tool for medical diagnostics, on-demand production of medicine and vaccines, and environmental monitoring on future space missions. Better Concrete Biopolymer Research for In-Situ Capabilities looks at how microgravity affects the process of creating a concrete alternative made with an organic material and on-site materials, such as lunar or Martian dust, known as a biopolymer soil composite. Using resources available where construction takes place makes it possible to increase the amount of shielding. These are just a few of the hundreds of investigations currently being conducted aboard the orbiting laboratory in the areas of biology and biotechnology, physical sciences, and Earth and space science. Advances in these areas will help keep astronauts healthy during long-duration space travel and demonstrate technologies for future human and robotic exploration beyond low-Earth orbit to the Moon and Mars through NASA’s Artemis program.
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📅 Mar 2011 📰 B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging
Aging is associated with a decline in B-lymphopoiesis in the bone marrow and accumulation of long-lived B cells in the periphery. These changes decrease the body's ability to mount protective antibody responses. We show here that age-related changes in the B lineage are mediated by the accumulating long-lived B cells. Thus, depletion of B cells in old mice was followed by expansion of multipotent primitive progenitors and common lymphoid progenitors, a revival of B-lymphopoiesis in the bone marrow, and generation of a rejuvenated peripheral compartment that enhanced the animal's immune responsiveness to antigenic stimulation.
Collectively, our results suggest that immunosenescence in the B-lineage is not irreversible and that depletion of the long-lived B cells in old mice rejuvenates the B-lineage and enhances immune competence.
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The Ageing Immune System and Health, ISBN-13: 978-3319433639 [PDF eBook eTextbook] Publisher: Springer; 1st ed. 2017 edition (October 10, 2016) Language: English 194 pages ISBN-10: 3319433636 ISBN-13: 978-3319433639 The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health. Valquiria Bueno: BSc, PhD. MSc and PhD in Immunology by the Federal University of São Paulo (UNIFESP). Post-doctoral fellow by the University of Oxford (2001). Professor and Researcher (since 2006) at UNIFESP; Department of Microbiology, Immunology, and Parasitology. Grants obtained (Brazilians institutions FAPESP, CNPq, and CAPES). Supervision of master students (n=5) and undergraduated students (n=13). Articles in Web of Science (n=35) and factor H=9, book chapters (n=5), Editorial Board Member (Plos One, Trends in Vector Research and Parasitology, Journal of Hematological Malignancies). Major interests: Ageing and Immune System, Cancer, Autoimmunity, Transplantation. Janet M Lord: BSc Human Biology at Oxford Brookes University, 1979 and PhD in Biological Sciences at Aston University, 1983. Founded her group with a Royal Society University Research Fellowship held from 1989 to 1998. In 2004 appointed Professor of Immune Cell Biology at Birmingham University and in 2013 became Head of the School of Immunity and Infection and Director of the MRC-ARUK Centre for Musculoskeletal Ageing Research and Director of the Medawar Centre for Healthy Ageing Research. Lord Cohen medal for outstanding contribution to ageing research, 2014: Glenn Foundation award for basic biological mechanisms of ageing. Thomas Jackson: Dr Jackson is a consultant geriatrician at the Queen Elizabeth Hospital Birmingham and also a Clinical Research Fellow at the University of Birmingham funded by AGE UK and the British Geriatrics Society. His main area of research is in Delirium and Dementia and in particular in the diagnosis of dementia in patients with delirium. He is also researching the biological basis of delirium in older adults, focussing on the role played by the endocrine-immune axis and inflammation. What makes us different? • Instant Download • Always Competitive Pricing • 100% Privacy • FREE Sample Available • 24-7 LIVE Customer Support
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The Ageing Immune System and Health, ISBN-13: 978-3319433639 [PDF eBook eTextbook] Publisher: Springer; 1st ed. 2017 edition (October 10, 2016) Language: English 194 pages ISBN-10: 3319433636 ISBN-13: 978-3319433639 The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health. Valquiria Bueno: BSc, PhD. MSc and PhD in Immunology by the Federal University of São Paulo (UNIFESP). Post-doctoral fellow by the University of Oxford (2001). Professor and Researcher (since 2006) at UNIFESP; Department of Microbiology, Immunology, and Parasitology. Grants obtained (Brazilians institutions FAPESP, CNPq, and CAPES). Supervision of master students (n=5) and undergraduated students (n=13). Articles in Web of Science (n=35) and factor H=9, book chapters (n=5), Editorial Board Member (Plos One, Trends in Vector Research and Parasitology, Journal of Hematological Malignancies). Major interests: Ageing and Immune System, Cancer, Autoimmunity, Transplantation. Janet M Lord: BSc Human Biology at Oxford Brookes University, 1979 and PhD in Biological Sciences at Aston University, 1983. Founded her group with a Royal Society University Research Fellowship held from 1989 to 1998. In 2004 appointed Professor of Immune Cell Biology at Birmingham University and in 2013 became Head of the School of Immunity and Infection and Director of the MRC-ARUK Centre for Musculoskeletal Ageing Research and Director of the Medawar Centre for Healthy Ageing Research. Lord Cohen medal for outstanding contribution to ageing research, 2014: Glenn Foundation award for basic biological mechanisms of ageing. Thomas Jackson: Dr Jackson is a consultant geriatrician at the Queen Elizabeth Hospital Birmingham and also a Clinical Research Fellow at the University of Birmingham funded by AGE UK and the British Geriatrics Society. His main area of research is in Delirium and Dementia and in particular in the diagnosis of dementia in patients with delirium. He is also researching the biological basis of delirium in older adults, focussing on the role played by the endocrine-immune axis and inflammation. What makes us different? • Instant Download • Always Competitive Pricing • 100% Privacy • FREE Sample Available • 24-7 LIVE Customer Support
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The Ageing Immune System and Health, ISBN-13: 978-3319433639 [PDF eBook eTextbook] Publisher: Springer; 1st ed. 2017 edition (October 10, 2016) Language: English 194 pages ISBN-10: 3319433636 ISBN-13: 978-3319433639 The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health. Valquiria Bueno: BSc, PhD. MSc and PhD in Immunology by the Federal University of São Paulo (UNIFESP). Post-doctoral fellow by the University of Oxford (2001). Professor and Researcher (since 2006) at UNIFESP; Department of Microbiology, Immunology, and Parasitology. Grants obtained (Brazilians institutions FAPESP, CNPq, and CAPES). Supervision of master students (n=5) and undergraduated students (n=13). Articles in Web of Science (n=35) and factor H=9, book chapters (n=5), Editorial Board Member (Plos One, Trends in Vector Research and Parasitology, Journal of Hematological Malignancies). Major interests: Ageing and Immune System, Cancer, Autoimmunity, Transplantation. Janet M Lord: BSc Human Biology at Oxford Brookes University, 1979 and PhD in Biological Sciences at Aston University, 1983. Founded her group with a Royal Society University Research Fellowship held from 1989 to 1998. In 2004 appointed Professor of Immune Cell Biology at Birmingham University and in 2013 became Head of the School of Immunity and Infection and Director of the MRC-ARUK Centre for Musculoskeletal Ageing Research and Director of the Medawar Centre for Healthy Ageing Research. Lord Cohen medal for outstanding contribution to ageing research, 2014: Glenn Foundation award for basic biological mechanisms of ageing. Thomas Jackson: Dr Jackson is a consultant geriatrician at the Queen Elizabeth Hospital Birmingham and also a Clinical Research Fellow at the University of Birmingham funded by AGE UK and the British Geriatrics Society. His main area of research is in Delirium and Dementia and in particular in the diagnosis of dementia in patients with delirium. He is also researching the biological basis of delirium in older adults, focussing on the role played by the endocrine-immune axis and inflammation. What makes us different? • Instant Download • Always Competitive Pricing • 100% Privacy • FREE Sample Available • 24-7 LIVE Customer Support
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The Ageing Immune System and Health, ISBN-13: 978-3319433639 [PDF eBook eTextbook] Publisher: Springer; 1st ed. 2017 edition (October 10, 2016) Language: English 194 pages ISBN-10: 3319433636 ISBN-13: 978-3319433639 The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health. Valquiria Bueno: BSc, PhD. MSc and PhD in Immunology by the Federal University of São Paulo (UNIFESP). Post-doctoral fellow by the University of Oxford (2001). Professor and Researcher (since 2006) at UNIFESP; Department of Microbiology, Immunology, and Parasitology. Grants obtained (Brazilians institutions FAPESP, CNPq, and CAPES). Supervision of master students (n=5) and undergraduated students (n=13). Articles in Web of Science (n=35) and factor H=9, book chapters (n=5), Editorial Board Member (Plos One, Trends in Vector Research and Parasitology, Journal of Hematological Malignancies). Major interests: Ageing and Immune System, Cancer, Autoimmunity, Transplantation. Janet M Lord: BSc Human Biology at Oxford Brookes University, 1979 and PhD in Biological Sciences at Aston University, 1983. Founded her group with a Royal Society University Research Fellowship held from 1989 to 1998. In 2004 appointed Professor of Immune Cell Biology at Birmingham University and in 2013 became Head of the School of Immunity and Infection and Director of the MRC-ARUK Centre for Musculoskeletal Ageing Research and Director of the Medawar Centre for Healthy Ageing Research. Lord Cohen medal for outstanding contribution to ageing research, 2014: Glenn Foundation award for basic biological mechanisms of ageing. Thomas Jackson: Dr Jackson is a consultant geriatrician at the Queen Elizabeth Hospital Birmingham and also a Clinical Research Fellow at the University of Birmingham funded by AGE UK and the British Geriatrics Society. His main area of research is in Delirium and Dementia and in particular in the diagnosis of dementia in patients with delirium. He is also researching the biological basis of delirium in older adults, focussing on the role played by the endocrine-immune axis and inflammation. What makes us different? • Instant Download • Always Competitive Pricing • 100% Privacy • FREE Sample Available • 24-7 LIVE Customer Support
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Spermidine: what it is, and what are the benefits
Spermidine is an "elixir" of youth and health, a safe, effective and all-natural anti-ageing product. You may not have heard of it yet because its use as a supplement is very recent, but it is found in many foods and is a powerful antioxidant, active on the mind and body. It cleanses our body from the inside and helps cell renewal, helps the brain stay active for a long time, and supports the immune system and metabolism. So let's see what it is and why you shouldn't miss it.
What is spermidine?
Spermidine is a biogenic polyamine, i.e. a substance that is produced by the body and is present in all organisms and in all cells of the body. Its name (perhaps not exactly inviting) is due to the fact that it was isolated for the first time in human sperm. It is linked to cell growth: when metabolism accelerates, spermidine increases, while it decreases when it slows down, and with age, it naturally tends to decrease.
It is a real natural booster that activates the renewal of the cells themselves through a process called autophagy, the one with which the body gets rid of the waste or damaged cellular components. A sort of "cleansing" that the body implements to improve its efficiency. The accumulation of dead cells is connected to various diseases and, in general, to the ageing of the organism: for this reason, spermadine can be useful within a longevity strategy.
The benefits of spermidine
The most recent research has highlighted several healthy properties that act on the organism as a whole.
Natural anti-inflammatory and anti-ageing
Spermidine is a natural anti-inflammatory. In particular, it seems to be effective against silent inflammation or inflammation, the one that accentuates with age and which, even if it remains low-level and undetected, still causes a lot of damage to the body. Spermidine works by unlocking cell regeneration and slowing down the ageing of tissues, including skin and hair!
Best friend
Spermidine regulates the level of blood fats, triglycerides and cholesterol. This is why it is a heart-friendly substance: it prevents cardiovascular disease, stroke and heart attack. Several studies have also linked spermidine to a lower risk of colon cancer: a diet rich in foods containing a lot of it (including various vegetables) is the healthiest for defending the intestine.
Strong immune defences
Spermidine improves the body's natural defences. In particular, it would be able to slow down immunosenescence, i.e. the process by which the body's response against bacteria and viruses is less effective with age, stimulating the production of antibodies.
Spermidine as a supplement
Spermidine can now also be taken in the form of a supplement. The most effective spermidine supplement is those containing extracts of raw, whole wheat germ obtained naturally through water without chemical agents. Alongside spermidine, other metabolic, stimulating and protective boosters are used, such as vitamin B1, astaxanthin or zinc.
The use of spermidine as a supplement can fill the deficiencies of an imperfect diet and enter into an all-around longevity strategy, promoting healthy ageing and meeting the needs of this substance which increase with age. Furthermore, these supplements also have positive and beneficial effects on skin, hair and a sense of well-being.
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Intermittent Fasting Can Be Your Gateway To Improve Rheumatoid Arthritis
The exact cause of this arthritis is unknown, but as with other autoimmune disorders. It has been theorized that it’s an interplay between genetics and environmental factors. RA is characterised by synovial hyperplasia and destruction of cartilage and bone which ultimately leads to multiple joint deformities. functional medicine doctor telemedicine
People with RA suffer from various co-morbidities like pain, deformed joints and even their life expectancy is lower as compared to the healthy population. The destruction in RA is because of the complex autoimmune process which involves the activation of T cells and CD4 cells. Patients with RA also show signs of early ageing like telomere shortening, impaired DNA repair etc.
Consults with Dr. Gupta
Is Current RA Treatment Adequate
With recent advances in treatment strategies, the new line of biologic medications have been introduced to help RA patients.
These medicines block certain inflammatory pathways, but at the same time also suppresses one’s immune system, plus they are really expensive and can come with a host of side effects. Another problem is that some patients don’t see improvement in their symptoms especially pain with these medications.
So the recent interest has been there to look for alternative/ comprehensive ways to manage pain and other comorbidities in RA patients.
Schedule consultation with Dr. Gupta
How Fasting Improves Rheumatoid Arthritis
Diet plays a very important factor in autoimmune diseases and that’s the reason different kinds of diets have been studied for RA patients.
One of the diets which has been popular recently is — intermittent fasting or fasting-mimicking diet. Fasting has been shown to decrease inflammatory markers in people and also bring about some changes which decrease the biological rate of ageing.
Fasting can help autoimmune diseases like RA by reducing inflammation and also through immunosenescence which basically means killing old and damaged cells and replacing them with young and functional ones. A study was done in RA patients by comparing the effect of fasting diet with normal diet for the patients.
Intermittent fasting improves rheumatoid arthritis
In this study, patients went through one time fast of 7-10 days followed by a vegetarian diet. The results not only showed improvement in clinical symptoms but also Lab values of ESR and CRP, which are a marker of inflammation in the system and are correlated with disease severity of RA.
Another study showed similar improvement in pain symptoms for patients after a period of fast. A modified fasting diet with low-calorie intake for 7-10 days was studied in RA patients and it showed clinical improvement in these patients.
Set up a call with Dr. Gupta
So Rheumatoid Arthritis does get better with Intermittent Fasting; but what exactly is it and how to do intermittent fasting.
Let’s discuss it here —
What is Fasting and How to do it
There are different ways of doing fasting and people sometimes choose the way that best suits their needs and lifestyle.
Prolonged Fasting: In this kind of fasting people will not eat any real food for a long period of time each week. Fasting days can be anywhere from 1 day a week to 3 days a week. People repeat this 1-3 day fast every week on a periodic basis or intermittently.
Intermittent Fasting: This refers to fasting for 16 hours and restricting your food intake window to only 8 hours. So typically people should not eat between 8 pm till 12 pm the next day. And will have 1-2 meals between 12 pm – 8 pm. They can do this every day or sometimes do it for 3-4 days a week.
Fasting mimicking diet: This is another diet which is getting popular these days, and the basis of this is to eat a diet which mimics fasting method. In this diet calories and carb are restricted while there is more good fat which improves insulin response and reduces inflammation.
Now the question is — which kind of fasting method is best for RA. The answer to this tricky question is that we really don’t know the exact diet which works for because there has not been a head to head trial to compare all these fasting methods.
My Suggestion to RA patients to find which fasting best diet that works for them —
What I suggest to my patients is the following combination —
Then follow it by intermittent fasting and do the 16:8 method (16 hr fasting: 8 hr food window) for the rest of the days in the week and take 1 day off during the week to reboot the system. So 1or 2 day of complete fast, 4 days of intermittent fasting and 1 day off every week.
intermittent fasting & RA
Fasting is a good way to keep your health in good check, especially if you have an autoimmune condition it can really make a difference. For Rheumatoid arthritis, there has been research which shows benefit not only in clinical parameters like pain but also saw improvement in the disease process. So fasting can be a part of RA treatment plan.
For More Info: Functional Medicine Doctor New York
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Functional Medicine Houston
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Omicron-specific Covid boosters appear to work well, new data says—r..
Omicron-specific Covid boosters appear to work well, new data says—r..
Omicron-specific Covid boosters appear to work well, new data says—regardless of the side effects you experience CNBCSigns of immunosenescence correlate with poor outcome of mRNA COVID-19 vaccination in older adults Nature.comModerna"s Bivalent COVID-19 Booster Elicits Superior..
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Omicron-specific Covid boosters appear to work well, new data says—r..
Omicron-specific Covid boosters appear to work well, new data says—r..
Omicron-specific Covid boosters appear to work well, new data says—regardless of the side effects you experience CNBCSigns of immunosenescence correlate with poor outcome of mRNA COVID-19 vaccination in older adults Nature.comModerna"s Bivalent COVID-19 Booster Elicits Superior..
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Omicron-specific Covid boosters appear to work well, new data says—r..
Omicron-specific Covid boosters appear to work well, new data says—r..
Omicron-specific Covid boosters appear to work well, new data says—regardless of the side effects you experience CNBCModerna"s Bivalent COVID-19 Booster Elicits Superior Antibody Responses Contagionlive.comSigns of immunosenescence correlate with poor outcome of mRNA COVID-19 v..
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Immunosenescence in Autoimmune Related to Periodontal Disease : A Review Article
Abstract
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by the development of autoantibodies and immune complexes associated with a variety of clinical manifestations and tissue damage. SLE is the production of reactive antibodies against the body’s own cells. SLE is multifactorial and most likely involves complex interactions between genetic, environmental, and hormonal factors. There is an aging process in immune cells due to changes in the innate and adaptive immune system compartments. This phenomenon is known as Immunosenescence, also occurs on autoimmune. One of the characteristics of elderly people is their inability to respond to vaccines and infections properly.
Discussion This situation also occurs in patients with systemic lupus erythematosus (SLE). In SLES patients, the aging of the immune system is the concept of inflammation; a state where there is a chronic pro-inflammatory status, characterized by increased levels of pro-inflammatory cytokines such as TNF, or IL-6, thereby stimulating a decrease in IL-2 and IFNγ and an increase in IL-10. Clotting factor and acute phase reactants under constant conditions. These biomarkers correlate with the incidence of various age-related diseases, such as heart disease, cognitive decline, cancer, and other physical disabilities. Immunosenescence and inflammation are the result of disruption in the cellular immunity properties of the innate and adaptive immune.
Conclusion: Defect production of T cells and B cells in autoimmune disease could results immune aging. This phenomenon causes neutrophil activation, forming antibody DNA consisting of immune complexes resulting in severe inflammation and tissue damage, as periodontal disease in oral cavity.
Read More About This Article Please Click on Below Link:
https://lupinepublishers.com/pediatric-dentistry-journal/fulltext/immunosenescence-in-autoimmune-related-to-periodontal-disease-a-review-article.ID.000222.php
Read More About Lupine Publishers Google Scholar Articles:
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