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inknerd · 5 years

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May Wrap-Up 2019

I’ve had so much to do this month; reading wasn’t really my first priority^^ Still, the last week I took the time to catch up to reading, and I read a lot of books I’ve wanted to read for awhile, and I feel like I’ve read a variety of books from ya to poetry to nonfiction, so that’s fun!

POETER TÄNDER BARA LAMPOR by EMILY DICKINSON (translation by ANN-MARIE VINDE) ★★★☆☆

| 130 pages | 3 weeks to read | Published 2017

So this is a collection of some of Dickinson’s poetry, who I haven’t read anything of so this was fairly exciting! It had both the English version and the Swedish translation together with notes from the translator, and so it took me awhile to read... + The more I read the more I liked it? I’m very happy the Swedish translation was available, because sometimes I just didn’t get what Dickinson was writing until I read it in Swedish and then reread the English one again. - With that said, I don’t think I will read any more of Dickinson soon. It was good but not really my kind of poetry.

DISORDER IN COURT: GREAT FRACTURED MOMENTS IN COURTROOM HISTORY by CHARLES M. SEVILLA ★★☆☆☆ | 256 pages | 1 day to read | Published 1992

You might have seen the funny tumblr post about this one. I did, was intruiged but waited to buy it until my friend told me she planned to study law. I saw the opportunity, bought it, read it, and then gifted it to my friend. + So some of these stories were hilarious, and it just shows how silly humans are even in serious situations like being in court for a crime. - Unfortunately, I didn’t find it as funny as I thought I would? Some things flew over my head because lawyer lingo/a bit more complicated English, sometimes it took some time before I got the joke and then it’s not as funny, y’know? Also, some of the jokes were quite dated.

A VERY LARGE EXPANSE OF SEA by TAHEREH MAFI ★★★★★ | 310 pages | 1 day to read | Published 2018

So I was excited for this one, and then people seemed to have mixed opinions on it (not disliking it, just not loving it as much as they’d expected to) so I waited until it came to my local library and then finally started reading it. And I LOVED IT! + PEAK ROMANCE! The main relationship is so cute and heart-wrenching, I wasn’t annoyed at Shirin’s family which is usually the case for me with more contemporary/romance-styled novels. This book had an important story to tell and it succeded in my opinion. - Idk, can’t come up with something totally obvious but I’d hoped for a more closed ending rather than the more open one I got.

CHILDREN OF BLOOD AND BONE by TOMI ADEYEMI ★★★☆☆ | 544 pages | +2 weeks to read | Published 2018

So I finally read this book! I’ve been sort of struggling with if I should give this three or four stars but in the end... *sweat drop emoji* I feel like I might have hyped this up a bit too much in my head. But in the end it was an enjoyable read and the reason it took my a while to read it was because I was busy, not necessarily that I found it boring. + i loved the worldbuilding, the magic system was interesting and it was explained in a way that didn’t feel forced. - The romance was...not overly good and the ending was...meh. And while the worldbuilding and so on made the story more spectacular the general plot was nothing special.

AVENGERS: DESTINY ARRIVES by LIZA PALMER ★★★☆☆ | 304 pages | 1 day to read | Published 2019

So this is basically Avengers: Infinity War in bookform, and I ordered because I wanted to read it before Endgame came out. Sadly! It showed up on the day of the premiere and I just skimmed through it the first time. Now I read it more carefully and, yeah, it was basically what I expected. + So most of it was just like in the movie, but the artistic take Palmer did on the characters thoughts and emotions during the battle was very interesting to read! And the illustrations were very nice too! - I can’t confirm this without checking the movie (and I don’t have the time) but some small things I remember being slightly different. Just small things, but considering it’s a book of a movie I feel justified in being somewhat picky.

CAPTAIN MARVEL: HIGHER, FURTHER, FASTER by LIZA PALMER ★★★★☆ | 246 pages | 1 day to read | Published 2019

Bought this at the same time as Destiny Arrives, because the cover just looked so pretty and the premise looked cool! + This was a surprisingly refreshing read. Some of the things Palmer came up with herself in Infinity War really resonated with me, and here she has the chance to come up with things on her own without being restrained by a movie (this book happens way before the movie Captain Marvel). It felt like this book had some important things to say. - I wished this book stretched longer, if so only to touch more on the story of Carol becoming Captain Marvel - but at the same time I was fine with how the book ended.

THE PRINCESS SAVES HERSELF IN THIS ONE by AMANDA LOVELACE ★★★★☆ | 156 pages | 1 day to read | Published 2016

This was a reread for me! I’ve worked with poetry together with my students this past month and I was motivated to read this again after seeing that the third collection in this series came out not too long ago. I reread this mainly because I wanted to see if my feelings on it had changed, and was pleased to see that they hadn’t! It’s still an interesting read.

I plan to reread the second one as well before I buy the third one!

THE TRAVELLING CAT CHRONICLES by HIRO ARIKAWA ★★★★☆ | 256 pages | 5 days to read | Published 2012

+ This is one of those books were you know what will happen, yet it still carries enough emotional impact that you cry when it ends. Reading from a cat’s perspective was very interesting and overall, this was such a nice read!

KVINNOR I KAMP: 150 ÅRS KAMP FÖR FRIHET, JÄMLIKHET OCH SYSTERSKAP by MARTA BREEN & JENNY JORDAHL ★★★★☆ | 119 pages | 1 day to read | Published 2018

This is a graphic novel depicting some of the history of the women’s rights movement. + The art was nice and they choose to include not only stories from Sweden and the west but also other parts of the world, which was great.

MUCH ADO ABOUT NOTHING by WILLIAM SHAKESPEARE ★★★☆☆ | 175 pages | 1 day to read | Published 2011/1598

My reading of Shakespeare’s plays continue! I remember watching the movie from ‘93 with Emma Thompson and Kenneth Branagh in class and really liking it! So when it came to choose the next play this is one I really wanted to read. + Beatrice and Benedick is so funny and charming, this made me want to rewatch the movie! - Outside of Beatrice and Benedick it was a pretty classic, background Shakespearian story going on, that was interesting but not as much as forementioned.

CRAZY RICH ASIANS by KEVIN KWAN ★★★☆☆ | 467 pages | 1 day to read | Published 2013

Finally read this! I wanted to see the movie since I’d heard so many good things about it, but it turned out netflix didn’t have it... I might watch it some other time, though! + I really flew through this. The descriptions of the luxury all around the characters was so much fun to read and the story had so many colourful characters to cling to. I might continue on with this series! - Despite getting through this very quickly, there were definitely parts full of information that I wasn’t interested in reading. I also expected this to be way funnier than it was. For some reason I was under the impression this was a sort of romance-comedy but while some things were funny (or, absurd?) it didn’t really meet my expectations. Some things about the romance parts didn’t click with me, either.

THE POET X by ELIZABETH ACEVEDO ★★★★☆ | 361 pages | 1 day to read | Published 2018

+ I liked that it was written in verse and I liked the story in itself... I don’t know what more to say.

TIGER LILY by JODI LYNN ANDERSON ★★☆☆☆ | 292 pages | 2 days to read | Published 2012

I’d heard shifting opinions on this one, but decided the premise sounded too interesting to not give a chance. I liked this book well enough, by the end, but it was far from a new favourite. + and - The reasons I liked it was also the reasons I disliked it. I liked some characterisations or aspects of them, and disliked some of them. I found the mix between Neverland and the real world somewhat confusing and wished the author would’ve either sticked more the original story or less, if that makes any sense. As far as Peter Pan-retellings go, I think this was interesting, still.

VIPER by BEX HOGAN ★★☆☆☆ | 400 pages | 2 days to read | Published 2019

This was is a brand new ya fantasy trilogy that I probably won’t continue reading... + While the first half of the book was pretty boring and predictable the second half was way better. I liked the main character the best in the middle of the book, same with the romance. - As mentioned, the start of the book was pretty lackluster. The main character seemed pretty meek considering the circumstances, the romance was bleh and the plot unoriginal. This book had several things that I’ve seen before over and over again and it didn’t work too hard on making them seem different than normal. Overall this story lacked any real depth.

#books #julia reads #reading wrap-up #reading wrap-up: may 2019 #book recommendations #book recs #book reviews #ya #booklr #my post

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ralphlayton · 4 years

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Get Ready For Video In 2021: Watch 5 Creative Examples of B2B Marketing on YouTube

What’s new at YouTube, and how are B2B marketers using the world’s largest video platform in creative and engaging campaigns? Let’s take a look! Google’s omnipresent YouTube brought in revenue of over $15 billion in 2019, has over two billion monthly active users (MAUs), and by some estimates is considered as the world’s number two search engine, making it nearly inescapable for B2B marketers seeking to host and promote video content. While not necessarily out of this world, YouTube’s orbit casts a wide swath in the B2B marketing universe. During the pandemic, video and webinar content has seen the largest increase in views according to recently-released PathFactory survey data, leading the Association of National Advertisers (ANA) to suggest that “Now Is the Time for B2B Content.” 64 percent of B2B buyers have increased their use of online video during the pandemic, according to newly-released report data from Google and Ipsos, which has also showed a whopping 88 percent increase in the usage of digital marketing overall. Another study by MediaPost and Bombora also saw increased interest in video during the global health crisis — a move that’s not surprising considering the power of video to drive authentic engagement in as little time as possible, as we’ll see in our five examples from B2B firms using YouTube in creative ways. First, however, let's look into the latest news surrounding YouTube.

What’s New At YouTube?

YouTube just launched a beta trial of its new YouTube Shorts 15-second vertical video creation function — presently only for users in India with a global rollout planned — joining Instagram’s recent test of its similar Instagram Reels capability. These short video features squarely spring from the popularity of TikTok, and have come at a time when the beleaguered company — now sought for acquisition by Oracle* — has faced significant challenges with its U.S. operations. Oracle’s proposed deal with TikTok — owned by ByteDance, its parent company in China — has met with initial approval by some advertisers. Oracle, which has recently forged partnerships with firms including Zoom, may at first seem like an odd fit for the acquisition of an app dedicated to short-form video creation and sharing, however should it succeed in controlling TikTok’s U.S. operations it would undoubtedly lend a significant infusion of enterprise-level business exposure. That could pave the way for increased B2B use of the type of short videos that can be created with TikTok, Instagram Reels, and YouTube Shorts, and with ever-more content being viewed on smartphones, vertical video undoubtedly has a massive audience. YouTube — which said that its Shorts feature provides a way to “discover, watch and create short, vertical videos on the YouTube app.” — has allowed users worldwide to upload short vertical video using the #Shorts hashtag, which will feature Shorts videos on YouTube’s coveted homepage. YouTube Shorts video can include music and feature multiple segments and playback speeds, along with timers for recording hands-free video, the firm said. The rise of vertical video brought on by TikTok and now Instagram and YouTube may end up making the format another standard digital asset for B2B marketing design teams, with its own strengths in areas such as mobile, and weaknesses in others such as display on traditional desktop and non-smartphone devices. On the advertising front, YouTube is planning to launch engaged-view conversions (EVC) metrics by the end of the year, bringing data on viewers who watch at least 10 seconds of a video ad and subsequently click away, yet nonetheless end up converting within a set number of days, YouTube recently noted. “By the end of the year, we will make engaged-view conversions a standard way of measuring conversions for TrueView skippable in-stream ads, local campaigns and app campaigns,” Nicky Rettke, YouTube director and product manager of YouTube Ads, explained in a recent post on the Google Ads & Commerce Blog. On the live-streaming front, YouTube has continued to embrace the multi-billion dollar esports vertical — which is comprised of more than 400 million players globally — offering a number of advertising opportunities for certain B2B brands. Whether 2021 will see more B2B brands sponsoring esports players or events remains to be seen, however B2B marketers may be taking a closer look at opportunities in esports, as Rosalyn Page recently examined in “What Brands Need to Know about Esports.” Live-streaming has also gained momentum in the relatively new area of streaming e-commerce, backed by firms including Amazon, and as Bloomberg News recently reported, the practice is expected to generate more than $100 billion in global sales in 2020. While more video is being watched than ever due to the pandemic, a significant amount of video seen on social media timelines is viewed with the sound turned off, making it more important than ever to ensure all video content has quality subtitling available along with a #Captioned hashtag. A good resource for information about video captioning for YouTube and elsewhere is Meryl Evans, an acknowledged “#Captioned pusher” and a fellow former bulletin board system SysOp. In B2B marketing, YouTube video content doesn’t necessarily always need to be traditional camera footage, as alternative formats such as animation are becoming easier to create than ever before, as Victor Blasco, chief executive of Yum Yum Videos recently explored in “Making Animated Marketing Videos That Engage Customers.” Now let's jump-cut to five recent examples of B2B marketers using YouTube to tell creative and engaging video stories.

1 — HP’s Dear Future Me

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In more ways than one storytelling is truly at the heart of powerful marketing messages, as witnesses in spades in HP’s new “Dear Future Me” video campaign, which offers a heartwarming spin on the practice of writing a letter to your future self, chronicling the stories of six recent high school graduates who wrote themselves such letters six years ago, when they were in the sixth grade. As part of the campaign, HP’s landing page for the initiative offers a downloadable PDF form where anyone can write their own letter, and incorporates a “We can’t wait to meet the future you” message to end the first of the two-part series of mini-documentary videos. The second episode lets current sixth graders write letters to their future 2026 selves, and shows them telling their own stories centered around the challenges of the pandemic. “Just try to remember: if you got through this year, you can get through anything,” one student encourages her future self. HP’s YouTube video descriptions for the series include handy links to the other video in the series, along with an extra link to subscribe to the firm’s channel — a simple yet often-overlooked practice that allows viewers who may have over years trained themselves to ignore YouTube’s own ubiquitous red “Subscribe” button.

2 — Adobe's Honor Heroes

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Adobe’s* “Honor Heroes” campaign, a collaborative global artistic effort to help support the battle against COVID-19, is centered around a single minute of video that has to date tallied nearly 3.5 million views. During that one minute the work of artists and other creative people is shown, each piece inspired by the pandemic. On Adobe’s YouTube channel the video’s description includes the campaign’s hashtag #HonorHeroes, and a link leading to a section of Adobe’s website with an image of each of the 116 people chosen as heroes, and a link to their respective Instagram profiles. The campaign’s video is also playable from the page. Adobe ties the page into their own Instagram account as well, encouraging page visitors to see more about the heroes campaign using the same hashtag this time to link to their Instagram profile and specifically those posts utilizing the campaign hashtag — a technique that can be effectively used to move customers to content on various brand social media channels. The campaign was also featured on the company’s blog, offering additional context about the campaign with insight from some of those involved, a donation link to the Direct Relief organization, and an embedded instance of the campaign’s YouTube video.

3 — Constant Contact's Power Hour

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Constant Contact regularly publishes video content to its YouTube channel — sometimes releasing up to 12 videos weekly — making it an important part of the firm’s social media efforts. Recent videos have included answering frequent customer questions, spotlight videos on businesses using the platform, a “Pro Series Power Hour” featuring ABC’s Shark Tank star Kevin O’Leary, customer success stories, and a visual series dedicated to using various elements of the firm’s service. For Kevin O’Leary’s video, Constant Contact has used a detailed description of the spot, with a link to learn more on their website’s blog along with links to five of the firm’s social media profiles.

4 — Deloitte's A World Reimagined

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In Deloitte's “A World Reimagined: The 2020 Global Millennial Survey” video, the effects of the pandemic on young people in the millennial and Gen Z demographic are visualized and brought to life, highlighting their energy for building a better world. In addition to watching the video, a micro-site for the campaign allows visitors to download the related report — which surveyed more than 18,000 millennials and Gen Zs across 43 countries — view a replay of the initial live-stream video event related to the effort, and offers an infographic for download and sharing. The site also includes a Twitter stream of tweets centered around the campaign’s #MillennialSurvey hashtag. Deloitte also successfully uses YouTube for its “Life at Deloitte” series of company culture videos, using storytelling to build empathy and trust, a tactic MarketingProfs explored recently in “Five Tips for Making Company-Culture Videos That Captivate Your Customers' Hearts.”

5 — Ernst & Young's Megatrends 2020 & Beyond

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In its “EY Megatrends 2020 and Beyond” video, Ernst & Young looks ahead to future trends and their overall larger meaning — one of its numerous YouTube channel videos exploring the firm's service offerings and helpful financial-related insight. Ernst & Young also uses its YouTube profile to share how it has responded to COVID-19, to announce its world entrepreneur of the year, and to archive its live-streaming video from LinkedIn* Live. Maliha Aqeel, director of global communications at Fix Network World and former assistant director of brand marketing and communications at Ernst & Young, sat down with our senior content marketing manager Joshua Nite to share a look at the role of B2B company culture in driving employee and customer satisfaction, in "Break Free B2B Series: Maliha Aqeel on How to Ace B2B Company Culture." [bctt tweet="Marketers and communicators within organizations have to take the charge. Our job is to take all of those values and say, 'Here's how it could look. Here's how the intangible becomes tangible.' @MalihaQ on #CorporateCulture #BreakFreeB2B" username="toprank"]

Snap A New B2B Take On Creative YouTube Marketing

via GIPHY YouTube offers much more to marketers than simply being the default spot to host and play back video, with ample social features for B2B brands to highlight other channels to follow, threaded viewer commenting if wanted, the forthcoming YouTube Shorts format, an ever-increasing number of ad formats and placement options, and remains a powerful platform for B2B influencers to engage their audience. We hope you've gained at least a few new ideas from looking at the latest news about YouTube, and that you'll find inspiration from the five fine examples we've explored from HP, Adobe, Constant Contact, Deloitte, and Ernst & Young. Video is only one facet of a well-rounded B2B marketing strategy, yet one that plays an important role in campaigns that attract, engage, and convert. Find out why firms including Adobe, LinkedIn, SAP, AT&T, Dell, 3M and others have chosen to work with TopRank Marketing — drop us a line. * Oracle, Adobe, and LinkedIn are TopRank Marketing clients.

The post Get Ready For Video In 2021: Watch 5 Creative Examples of B2B Marketing on YouTube appeared first on Online Marketing Blog - TopRank®.

Get Ready For Video In 2021: Watch 5 Creative Examples of B2B Marketing on YouTube published first on yhttps://improfitninja.blogspot.com/

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samuelpboswell · 4 years

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Get Ready For Video In 2021: Watch 5 Creative Examples of B2B Marketing on YouTube

What’s New At YouTube?

1 — HP’s Dear Future Me

youtube

2 — Adobe's Honor Heroes

youtube

3 — Constant Contact's Power Hour

youtube

4 — Deloitte's A World Reimagined

youtube

5 — Ernst & Young's Megatrends 2020 & Beyond

youtube

Snap A New B2B Take On Creative YouTube Marketing

The post Get Ready For Video In 2021: Watch 5 Creative Examples of B2B Marketing on YouTube appeared first on Online Marketing Blog - TopRank®.

from The SEO Advantages https://www.toprankblog.com/2020/09/5-creative-b2b-marketing-youtube-examples/

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investmart007 · 6 years

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LOS ANGELES | Masters of rock: Climbers smash El Capitan's climb record

New Post has been published on https://is.gd/XYcHWz

LOS ANGELES | Masters of rock: Climbers smash El Capitan's climb record

LOS ANGELES (AP) — Days after two of the world’s most celebrated rock climbers twice set astonishingly fast records on the biggest wall in Yosemite National Park, they did it again Wednesday, breaking a mark compared with track’s four-minute mile.

Alex Honnold and Tommy Caldwell scaled El Capitan’s 3,000-foot (915-meter) sheer granite wall in 1 hour, 58 minutes and seven seconds, Honnold said.

The blisteringly fast pace capped weeks of practice climbs up the so-called Nose route that runs up the middle of the massive monolith towering above Yosemite Valley. It also came just days after two speed climbers fell to their deaths on El Cap.

Honnold didn’t think they were on a record time until he pulled his phone out and looked at his timer as he ran for the tree that marks the official finish line, he told The Associated Press by phone as he hiked down from the summit.

“Oh my god, we’re doing it,” he thought to himself as he secured the rope around the tree and hoped Caldwell would hustle up the final pitch. “It was slightly emotional when we finished it. I had a wave of, ‘Oh wow.’ I’m pretty proud we saw it through.”

The duo broke the Nose record three times in the past week, carving more than 20 minutes off a mark set last year.

It would have been easy to stop after their May 30 record of 2 hours 10 minutes 15 seconds or Monday’s mark of 2 hours, 1 minute and 53 seconds, Honnold said.

Hans Florine, who has held the speed record for the climb on and off between 1990 and 2012 — the last time with Honnold — said the new mark is equivalent to the ongoing quest to break the two-hour marathon or Roger Bannister’s 1954 achievement in the mile.

“We were pushing the five-hour barrier before and then the four-hour barrier and then the three-hour barrier. So which one of those is the four-minute mile?” Florine said before the mark was broken. “I think it is getting close.”

Climbing times on El Cap have fallen precipitously since the first ascent of the cliff 60 years ago by Warren Harding and two others. That milestone took 12 days in a final push that followed 48 days of advance work over 18 months as Harding pounded bolts into the route to aid his climb.

“As I hammered in the last bolt and staggered over the rim, it was not at all clear to me who was the conqueror and who was the conquered,” Harding said afterward. “I do recall that El Cap seemed to be in much better condition than I was.”

Yosemite is mecca for climbers around the world because of its vast array of beautiful soaring granite walls and peaks. El Cap, though, looms largest and offers 58 distinct routes. The Nose is the best known and typically takes accomplished climbers four or five days.

Climbers jam their hands and feet into finger- and fist-width cracks to inch their way up the vertical wall. Ledges large enough to camp on offer respite, but sometimes there is little more to grasp or perch on than a sliver the width of a few coins. Other cracks come abruptly to an end in a sea of smooth granite, forcing climbers to swing 30 feet left or right to find the next hand or foothold.

“It’s a very complicated route,” said Daniel Duane, author of the book “El Capitan: Historic Feats and Radical Routes.” ”It meanders all over the place and it has pendulum swings and bolt ladders and there are little variations where you can go this way and instead of that way, so there’s a ton trickery involved in shaving off time.”

Speed can come with a devastating price. Climbers are roped together for safety, and they clip their lifeline into protective pieces that they place in cracks along the way to catch them if they fall. But the amount of gear in a race against the clock is pared to the bare minimum to save weight, and climbers sometimes move in tandem with neither anchored to the rock.

The two expert climbers killed Saturday were speed climbing El Cap’s Freeblast route in tandem when one fell and pulled the other 1,000 feet to their deaths, according to reports.

Last year, Quinn Brett, a former women’s speed record holder on the Nose, was trying to improve her time when she took about a 100-foot (30-meter) freefall and slammed a ledge below, leaving her paralyzed below the waist.

Caldwell took 60-foot and 100-foot falls during the three weeks of practice runs and record attempts but was uninjured, said photographer Austin Siadak, who has been shooting video of the team for a documentary.

“It was pretty scary because it was such a gargantuan fall,” Siadak said of the larger fall. “I saw him hurtling upside down through the air and then bouncing on the end of the rope.”

But once Caldwell came to a rest, he quickly regained his composure, chalked up his hands and swung back over to a crack that he could climb back up.

In 35 years of climbing, Florine’s worst injury until this year was when crashed into a rock wall and knocked out a tooth. Last month, he was climbing the Nose in a day with a friend and took a short fall that broke both his legs and had to be rescued by helicopter.

Florine, 54, has been at the forefront of chasing the speed record, but he noted that the fastest climbers are still covering just over 20 feet (6 meters) a minute. Sport climbers who sprint up short walls in competition can cover triple that distance in 5 seconds.

Big wall climbing, of course, is another beast entirely. It takes a different type of endurance and composure to ascend 32 rope lengths with nothing but open air below.

Honnold, 32, and Caldwell, 39, are arguably the biggest stars of rock climbing now with multiple accomplishments together, with others and, in the case of Honnold, on his own.

Caldwell and Kevin Jorgeson earned fame outside alpine circles in 2015 when they were the first to climb one of the world’s hardest route on El Cap, using nothing to assist their 19-day ascent and only ropes and gear to protect against a fall.

Honnold holds the honor of being the only person to have climbed El Cap solo without a rope or any protection, a perilous feat that earned him widespread praise and also criticism for being reckless.

The two climbers represent a sort of “dream team” from a generation who honed their craft in rock gyms and “are showing up in the outdoors with a radically different ability level than they used to,” Duane said.

With 400 rock gyms nationwide, the sport is open to people far from crags, boulders and other climbing features that were the only options a few decades ago, Duane said. That has created a broader spectrum of people being introduced to the sport. It’s more likely to identify and develop those with a natural gift for climbing.

High schools now offer climbing programs after school with expert instructors and hours of training each day. So even with climbers like Honnold and Caldwell setting new high marks, records are made to be broken.

“At one level it’s hard to imagine, gosh, how could anybody get better than those guys?” Duane said. “Yet sports move that way and they keep moving and they never stop moving. Climbing is a lot further along than it was 30 years ago on that curve toward athletic maturity. But I don’t think it’s anywhere near the outer limits.”

By BRIAN MELLEY by Associated Press – published on STL.News by St. Louis Media, LLC(R.A)

#climb record #Climbers smash El Capitan #Los Angeles #Masters of rock #TodayNews #Yosemite National Park

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type2diabetestreatments-blog · 7 years

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JDRF Research Summit: The Who, What, When and Why of Type 1 Diabetes

New Post has been published on http://type2diabetestreatment.net/diabetes-mellitus/jdrf-research-summit-the-who-what-when-and-why-of-type-1-diabetes/

JDRF Research Summit: The Who, What, When and Why of Type 1 Diabetes

As reported yesterday, the JDRF Capitol Chapter hosted their first annual research summit in Bethesda, MD, on Saturday. Just days before, the staff reported that they were expecting more than 400 people. Not bad! The line-up included talks on the rise of type 1 diabetes, preventing type 1, the latest in artificial pancreas technology, and why human studies are crucial for the next steps in research.

I sat alongside several other D-bloggers, including Scott Strumello, Ginger Vieira, and Bennet Dunlap. Also on hand were med writer Miriam Tucker and Kevin, who's most recognized for his contributions to diabetes logbooks. We had our very own table, sponsored by HealthCentral Network.

Below is my wrap-up of what we learned. NOTE: lots of links are included, because there's of science at work here.

Dan Hurley, author of Diabetes Rising

The summit launched with a presentation by author Dan Hurley, a PWD with type 1, who has spent years researching the rise in type 1 diabetes. Originally, the theory was that some virus triggered the crazy immune response that causes type 1, but Dan says that idea "never really gelled." Dan shared five hypotheses for why there is an increase in type 1, which include: the "hygiene hypothesis," the "accelerator hypothesis," lack of vitamin D, pollutants and infant formula.

The "hygiene hypothesis" essentially says that "nothing causes type 1 diabetes" — as in, the cleanliness of the developed world and the lack of infections for T-cells to fight causes the immune system to go crazy because it "gets bored." The "accelerator hypothesis" supposes that growth factors in the modern-day world put stress on the pancreas. Children nowadays grow much more and faster than they did in previous centuries, and this theory proposes that rapid body growth causes insulin resistance, and eventually also the death of the beta cells. Lack of vitamin D, pollutants and infant formula have all been discussed previously as theories for why type 1 diabetes is on the rise. At the blogger table, we discussed the simple explanation that cases of type 1 might appear to be on the rise simply because of higher survival rates (i.e. children aren't dying from diabetes) and better medical reporting of new cases in recent years.

Dr. Henry Rodriguez, Medical Director, University of South Florida Diabetes Center

Given that this summit was mostly targeted toward D-parents, it was no surprise that a lot of attention was focused on the issues and challenges facing children with diabetes. These include:

- lack of a national health plan

- fragmentary nature of health care (lack of cohesion between providers — which we like to call "The Myth of the Healthcare Team")

- inadequate mental health services

- limited healthcare literacy (people don't know enough about their own illness or treatments for it)

- inconsistent care in schools

- lack of a national registry for people with diabetes (traditionally, there were no real stats for type 1 diabetes, although the Helmsley Trust is working to change all that!)

- persistence of DKA at diagnosis (DKA is deadly, showing that early detection of the disease is badly needed)

One project you may know of that the JDRF is working on is the T1D Exchange, which aims to enroll children with Type 1 diabetes across the country to get a sense for when they were diagnosed, how they manage and treat their diabetes, and get a sense of benefits for different treatment strategies.

[Dr. Ed Damiano was up next, but we interviewed him yesterday, so you can check out the video here.]

Mark Atkinson, Director of the Diabetes Center of Excellence at the University of Florida, Gainesville and Director of JDRF's nPOD (pancreas donor) Project

Dr. Atkinson shared his view of 10 diabetes-related "pedagogical dogmas," which are basically opinions that become accepted by authorities as cold, hard fact. One interesting dogma he debunked is the idea that after a few months, beta cells are all gone. In reality, that isn't always the case. There are sometimes insulin-positive cells remaining, and there is an idea that these tiny amounts of insulin-producing cells can actually cause challenges to our diabetes management (!) Another dogma is that NOD (non-obese diabetic) mice are effective tools for finding a cure. We all know that mice are always used for diabetes cure research, but did you know that diabetes has been cured in mice four hundred times? (And yet again this week!) Clearly, mice are doing squat for us people, and that is why, Dr. Atkinson says, we need more human trials.

Dr. Aaron Kowalski, VP of Therapeutic Therapies at JDRF

Dr. Kowalski and his brother both live with type 1 diabetes, and it's always interesting to hear perspectives on research from those who know it best. The goal of the artificial pancreas is to eventually manage diabetes with minimal patient input, but Kowalski (and Damiano) explained that it's going to come in phases. Right now, they are working to gain FDA approval for insulin pumps with auto shut-off systems, like the Minimed Veo, which is not approved in the US for "safety reasons." Dr. Kowalski also points out that a major flaw in our D-management toolbox is that current insulins work too slowly (although at least one Pharma company disagrees there). Plus, there are other hormones that are affected by diabetes: glucagon, amylin, and leptin. Therefore, all of our future management tools and the cure itself will have to account for a lot more than just fluctuating blood sugars, Kowalski says.

Dr. Jerry Palmer, University of Washington, Investigator in the Diamyd DiaPrevent GAD Study

There have been several different studies on preventing type 1 diabetes. Why do we care about prevention if we already have it? Well, the immune system response is still active even after diagnosis. That means there's hope for stopping the disease in its tracks, IF it is caught very early. On the flipside, when a person receives an islet cell transplant, the disease is stopped for a while, but will eventually return.

Did you know that oral insulin has been studied as a possible prevention for diabetes? Although oral insulin is degraded in the immune system, in one study, those who took oral insulin delayed their development of type 1 diabetes by about five years, with some people experiencing a 10-year delay.

Things that definitely don't work for prevention are: vitamin nicatinamide (vitamin B3) and parenternal insulin (injections of insulin prior to diagnosis). Oral insulin is still under investigation, as well as nasal insulin, new types of infant formulas, and omega-3 fatty acids. Other proposed options include probiotics, anti-CD3, and the GAD vaccine.

Unfortunately I missed the final session, presented by Bill Parsons, Legislative Director to Congressman Chris Van Hollen, due to my interview with Dr. Ed Damiano. Parsons presented "the view from Capitol Hill," and I understand he talked about President Obama's push for expanded stem cell research, a hotly debated topic. He talked about healthcare reform and research funding, and also reported that, "Obama is concerned about the pace of regulation in the USA."

At the end of the day, there was a Q & A with all of the speakers. One comment I wanted to share was a response by Dr. Aaron Kowalski to the question about when there might be a cure for type 1 diabetes, considering all the statements made by doctors and JDRF staff that a cure is "10 years away." Dr. Kowalski said, "The idea of a cure has evolved. Islet research turned out to be a lot more challenging (than expected). We have to be more realistic, and (a cure) will be evolutionary. We won't be able to just snap our fingers." Well, that sure is clear.

In this video, my fellow bloggers also shared some of their feedback about the summit:

Big thanks to everyone involved!

Disclaimer: Content created by the Diabetes Mine team. For more details click here.

Disclaimer

This content is created for Diabetes Mine, a consumer health blog focused on the diabetes community. The content is not medically reviewed and doesn't adhere to Healthline's editorial guidelines. For more information about Healthline's partnership with Diabetes Mine, please click here.

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