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#paracetamol is a wonder drug
whoops-im-obsessed · 9 months
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Hello!! Here is your friendly reminder that you CANNOT build a resistance to paracetamol (acetaminophen, tylenol) l. It doesn't work like that, you could take it everyday for 50 years and it would work the same (you probably shouldn't, but you could). It is also a build up drug, so it will work better if you take it consistently!! Take your goddamn pain relief!!!!
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kaeyx · 7 months
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Haha more Yan!Chuuya
Except this time you're perfectly okay with being kidnapped (let's be honest if it was him we'd all be chill with it)
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A groan snaps him out of his thoughts and Chuuya leans closer, watching as your face screws up and you grimace. He can imagine you have a pretty bad headache, what with all the shit still in your system. You sniff and blink your eyes open, one hand reaching up to rub them and making him swim into view.
He sits next to you, watching as you sleep, holding your hand. It had been so, so easy, it worried him. What if the person slipping you that drug hadn't had good intentions? Chuuya shudders at the thought. You'd been so vulnerable, so exposed... he was so lucky. You hadn't been snatched up by someone else, someone who could hurt you.
"Chuuya?" You groan, moving to get up.
"Yeah, it's me. Don't move too much, I've got painkillers." A hand on your shoulder guides you back onto the pillows of his bed, and he hands you the promised paracetamol which you take gladly.
"What... where am I?"
His heart seizes. You're just so beautiful, turning to him for help and advice, lying in his bed, in his room; Chuuya wishes he could keep this moment forever. But there's also dread in his stomach. What does he tell you? How does he explain what he's done?
You sit up and he doesn't stop you, hearing the clink of the manacle on your ankle. The sound stops, and he knows you've seen it too.
"Chuuya.....can I leave?"
He chews the inside of his cheek, unable to look you in the eye. "I can't let you do that."
There's silence for a few long seconds, only interrupted by the heart hammering wildly in his ears. Will you yell? Hit him? Beg for him to let you go? Chuuya knows he'd deserve it. He feels the bedsheets shift as you draw your knees to your chest, and braces himself.
"And...." your voice is neutral, tentative, "you'll take care of me?"
"Always," he promises immediately, looking back up at you without even considering what expression you might be wearing. "I promise."
You're chewing the inside of your mouth, brows drawn together in a pretty little frown. Chuuya wishes he could kiss the worry off your face, he wishes there was another way to guarantee you wouldn't be ripped away from him. Your throat bobs and you reach out, tentatively, fingers brushing against his cheek.
"You'll keep me. You'll stay with me?" Chuuya can practically hear the gears turning in your head. Your skin feels so nice against his. He wonders why you're not yelling yet.
"Yes," he responds, quiet, heart in his throat.
"You could have just asked."
Chuuya laughs, a little hysterical. "Yeah no problem! Mind if I kidnap you and keep you locked up so nobody can hurt you?"
You laugh too, a sound he'd been so ready to never hear again, tugging on the front of his shirt. He leans forward and lets his elbows rest on the bed, looking up at your smile. It's even better up close.
With another tug and a muffled moan of surprise your lips meet his, one of your hands sliding into his hair and grabbing a fistful of the auburn strands. Chuuya whines, giving in to the impulse to throw his arms around your hips and dragging himself as close to you as he can, heat spearing through his stomach as he feels you groan into his mouth. Barely pulling back he swings a leg up onto the bed and across yours, settling on top of you as he chases your lips again, hands grasping at your shoulders and waist.
You let your hands fall onto the pillow, looking up at him in breathless excitement. His hands grasp yours, threading your fingers together and pressing them against your chest. His hair is falling in thick waves around his face, pink covering his face, and he's panting a little.
"Please tell me it's real," you breathe.
Chuuya laughs, leaning down again. "I could say the same thing."
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somecunttookmyurl · 8 months
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the liver thing isn't like a disease or a disorder or anything it's just genetic variance and can go either way. it's that guy who needs 2 paracetamol instead of 1, or that absolute bastard who only has to take half a pill
it becomes a Fucking Annoyance when you're far enough away from the bell curve that shit just doesn't work, or doesn't work enough to warrant taking. it is extra a Fucking Annoyance because you will go your whole life wondering why things simply don't affect you whilst doctors repeatedly either accuse you of lying because they don't know it can be a thing, or go through drug after drug after drug all metabolised the same way and which naturally don't work before giving up.
the fact it's considerably more common in people with chronic pain conditions (for reasons), and people with chronic pain being labelled drug seekers, are probably related.
the fact that ultra-rapid metabolisation on typically the most annoying pathway is most common in people from the middle east and... i think north africa? but very rare in white people (without chronic pain) is also for sure something ain't it (actually it's way more common in painless white people to go the other way and need less drugs. 7-10%. if you were wondering. you weren't)
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pigeonwhumps · 1 year
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"That's gonna scar"
MD-264N masterlist
Febuwhump day 5: "that's gonna scar"
Asha sews up Morgan's gunshot wound when it refuses to close.
1.3k
CWs: self-dehumanisation, stitches, implied past non-con drugging, mentioned brainwashing, mentioned expectations of death, conditioned whumpee, living weapon
"Are you sure you don't want any stronger painkillers?" asks Asha, concerned. All Morgan's consented to taking are a couple of paracetamols, and while Asha can understand why after seeing the track marks on their arms, she's spoken to Rhian and she's not sure it's going to be enough today. She's not sure it's enough normally, honestly, but Morgan's gunshot wound isn't healing properly after the packing and now it needs stitches. Which means far more intense pain.
"No, thank you, sir. Asha."
Asha exchanges a glance with Rhian. A bit of a setback, but that's to be expected after yesterday. At least they're using her name as well.
"If you're sure. This is going to be painful, so let me know if you change your mind and need me to stop at any point, alright?"
"Yes, Asha."
"Good."
"You can squeeze my hand as much as you like," says Rhian softly, resting her hand in Morgan's. They wrap their fingers gently around it.
"Morgan, can you lift your leg so your ankle's on the pillow here? It's covered in a towel, even if we make a mess it'll be fine. I need your ankle slightly elevated and for me to be able to get to it easily." Morgan swings their leg up on the bed and turns slightly, leaning against Rhian, back to her chest. "That's it. I'm going to start now, you don't have to watch."
"Concentrate on your breathing," says Rhian, as Asha unwraps the bandage around the wound and winces. "Nice and deep and even, copy me."
Morgan does their best as Asha cleans the area around the wound before picking up her needle and thread. This is going to be the painful part. Her patient squeezes their eyes shut at the sight of the needle touching skin.
Asha pushes through the skin with only a little resistance and Morgan whimpers. They bite their lip, clutching Rhian's hand tight, letting out pained cries as Asha pulls the thread through.
Rhian starts humming.
It's a low tune, a soft lullaby that Asha recognises as one of Rhian's self-soothing techniques from when they first joined. It seems to be working wonders on Morgan too, their eyes drifting shut. After a couple of verses they join in hesitantly, the humming replacing their sounds of pain. Their breaths are still hitching, their face is white, but they're a little better.
Asha smiles slightly to herself as she stitches up the wound. They're perfect for each other. Rhian's doing much better with someone to care for, and Morgan's recovery is going better than Asha could ever have predicted.
"Alright, I'm all done with the stitching. This'll probably scar but at least it has a better chance of healing now." Morgan snaps their eyes open and watches intently as Asha wraps a bandage over the top of the stitches. "That should keep it clean and stop you catching the stitches on stuff."
"Thank you, sir. Asha."
"No problem. You were very brave. Would you like a fruit pastille?"
Morgan's eyes light up and they nod. Asha grins. Rhian was right, they really do have a sweet tooth. She holds out the jar. "Here. Take a couple."
"Thank you."
Once Morgan's chewing on a sweet, Asha says carefully, "How are you both? You look exhausted."
Morgan glances back at Rhian, who nods, squeezing their hand. "This weapon malfunctioned last night. It, I, I had a nightmare. And it disturbed Rhian and it is so sorry."
"I told you, it's fine, sweetheart," murmurs Rhian, before turning to Asha. "It was worse than they've had in over a week. We barely slept at all."
"Hey. You'll get better, Morgan. Maybe not all the way, but recovery's never linear. Rhian can tell you that."
Rhian nods. "Definitely."
"If you're okay on your own for a moment, I need to speak to Rhian quickly."
Morgan nods, and Rhian slides out from under them, following Asha across the room. Her voice is hushed.
"What is it?"
"It wasn't just Morgan's nightmare last night, was it? You look too distressed for that."
Rhian sighs and shakes their head, raking their hand through their hair. "I had a nightmare too, but that's normal. Nothing unusual about it. Been having them for years. But Morgan… they said that they didn't understand why we wanted a malfunctioning weapon. They asked why we hadn't decommissioned them yet. I mean, what do I say to that?"
Asha feels queasy. Morgan's barely grown and already they're expecting to die for being emotional and hurt.
"Reassure them we care, for as long as they need. And hopefully they'll understand our intentions eventually."
"Right. Hopefully. And maybe they'll consider themself a person eventually, too. Is that all you wanted to ask about?"
"Yeah. We can go back over now. I have their present with me too."
Rhian grins. "You finished it!"
"Of course I did."
They head back over, Rhian pulling Morgan gently against her under the window as Asha packs away her equipment. She can just hear Rhian whispering soothingly to Morgan, very obviously trying to contain her excitement. Asha pulls a lumpy package wrapped in scrap paper and string out of her bag, and hands it to Morgan. They frown down at it.
"It's a present for you. I meant to finish it a while ago but I got ill and then I was busy, but here you are."
Morgan blinks. "For me?"
"Yeah. Nothing bad, I promise. Go ahead and open it."
Morgan examines it for a full minute, Rhian almost bouncing behind them, before pulling at one end of the string, undoing the bow. The paper falls with the string, revealing a toy owl made out of scraps of fabric. It's not amazing, the wings are uneven and so are the button eyes, and the fabric's a bit of a mish-mash of anything she and Rhian could find regardless of the colour or texture, but Morgan picks it up delicately, like it's a treasure. They look a little bewildered.
"Morgan? What's wrong?"
They swallow, looking up at her. "What's the purpose of this gift? If it should be obvious this weapon apologises, but it does not understand."
"It's just a present, sweetheart," says Rhian. "It doesn't have a purpose. Though I guess if you need one, we can say it's to help you recover. You can cuddle it and it'll hopefully make you feel better. And the different textures are a great sensory thing. I have a similar one, you've seen it."
"It is only a weapon, it is not worthy of such a present. But it is very grateful."
Asha smiles, noticing that Morgan's already clutching the owl close to their chest. "Do you want to name it?"
"Archimedes," they say after a pause. "If that's acceptable."
"Archimedes," repeats Rhian thoughtfully. "Good name."
As Morgan sinks further into Rhian, eyes full of badly-hidden relief, Asha wonders if they ever watched The Sword in the Stone before they were brainwashed by the government. Maybe it was their favourite film. Maybe it was a sibling's favourite. Did they watch it over and over again? Did they learn the songs, did they annoy their family with them? Did they get annoyed by them?
Asha doesn't know. None of them do.
Until now, it hadn't occurred to her just how much they don't know about the newest member of their family. They don't know how old Morgan was when they were taken, where they lived, who they loved and were loved by in return (because surely, surely someone cared). They don't even know what their name was. Blue's working on hacking the retrieved memory card that may well have helped Morgan escape, but until then…
Just who do they have in their care?
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fallenwhumpee · 4 months
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YIPPEE WE LOVE INTERVENTION ON SELF-NEGLECTING WHUMPEES!! Gotta wonder what Leader was doing up at the same time, though 🤔 ANYWAY WE LOVE CARETAKERS BASICALLY MANHANDLING THEIR WHUMPEES INTO GETTING SOME REST!!!!
Also for the drug whumper!! That's just cruel my man!!! /pos even if whumpee's team finds them, what then??? Recovery is such a slippery slope and the withdrawal already seems pretty severe...
Also!! Whumpee with the painkillers!! That is not responsible you silly goose!! Paracetamol damages your liver you know!! And developing a resistance to painkillers cannot be Good!!
Anyway the whump is scrumptious as always!!! I'm doing good, hbu?? Also yeah, I'm terrible w/comfort too lol I just keep whacking my whumpees against the wall, if you couldn't tell 😭 would be nice if I figured out how to write comfort too haha
:D anon
Leader was winding up Caretaker to drag whumpee back to bed with also planning to do the same thing as whumpee lol. And it worked! Now Leader can do the "urgent" job and whumpee can rest.
Whumpers should be cruel! That's what their job description says, at least. And the team will have their hands full with whumpee if the rescue comes. Though there wouldn't be a team if whumpee finally tells whumper something they shouldn't.
I think that whumpee would be more worried to develop a tolerance than liver damage.
Thank youu! Yeah, I will have to figure that out sooner or later though. Whumpees will start a revolt if I keep throwing them from wall to wall. And I'm good! Survived through half of my exams, and I also have two more pieces scheduled. I quite liked how they turned out to be honest.
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race-week · 2 years
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Hiii! Following lando's comment, i was just left wondering what types of "drugs" are allowed, a few decades ago i don't think they even allowed paracetamol
have the rules changed to accommodate cold/headache/general meds?
Thank you, i hope you and steven have a nice day!!
Hi, thank you - I hope you have a nice day too.
A couple months back (or last year - I honestly have no concept of the passing of time at the moment) there was a very long discussion on my page about doping and drug use within F1 as well as the regular drug tests that F1 drivers have to undergo.
Generally I believe that the FIA follows the list of banned substances produced by WADA (world anti-doping agency) but there’s actually very little information about painkillers that aren’t narcotics
There’s many ex drivers, from years back (Stirling Moss being one of them) who have admitted to using amphetamines, Benzedrine or Dexedrine to stay alert in the car, especially on long races. I don’t remember them actively stopping drivers from using pain relief, but I could be wrong
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When It Is More Than Just A Headache!
We all suffer from the occasional headache, but when the headache become debilitating then it is certainly more than “just a headache”. Of course, for most people the answer is to just pop a paracetamol or two and hope that it does away. But when it doesn’t, or those medications are starting up secondary problems such as in the digestive system or other side effects in the body, then they are not the best answer. Our chiropractors in Manchester have many patients who consult them seeing chiropractic care as along term solution to both headaches and migraines.
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Chiropracticis a complementary medicine solution
In the past few decades there has been a growing trend to seek out alternative solutions, not only to headaches but to many health problems. But the very word “alternative” now has some extra connotations that can set it into the world of the weird and the wonderful in the minds of some. So, let’s use the word “complementary”! Within these areas there are several other highly regarded treatments such as acupuncture, reflexology, massage,chiropractic and many more within this bracket. It is an evolving area and scientific research is always ongoing to further establish the results from these complementary treatments. Chiropractic medicine is one area which is increasingly accepted as becoming accepted into the mainstream of health care.
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How your chiropractor views your constant headaches
In the case of headaches, chiropractic is now seen as providing sufferers with a natural path for treatment and prevention. Our experienced chiropractors at Manchester chiropractors are professionals  who view their patients in a holistic way. Looking at the whole body and seeking to find the source of the problem, rather than simply prescribing medication to alleviate the symptoms. Whilst in some cases treatments work in conjunction with conventional medicine where necessary, it is their primary focus to identify and treat the root cause of your condition through natural, non-invasive systems and therapy. In this way your chiropractor in the Northern Quarter of Manchester aims to resolve and prevent recurrence,rather than alleviating it only.
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A natural solution to stress, tension and cervicogenic headaches
In the 21st century alternative/complementary medicine is sought by many people who value their well being and are looking for ways to avoid a continual intake of prescription drugs and over the counter quick fixes. Whilst Chiropractic treatments are increasingly seen as moving into the medical mainstream(because genuine results are seen from the treatment both immediately and long term),they steadfastly maintain their natural approach. This offers patients the quality healthcare of a chiropractic consultation and assessment to fully understand their current challenges and a care plan to relieve them of those headaches, aches and pains.
What it does and can it work for you?
Chiropractic involves spinal manipulation having ascertained by consultation and examination, exactly what is the causeof the recurring headaches you are experiencing.Headaches which can affect your whole way of life. Following their chiro treatments, Manchester Chiropractic patients say that chiro results in significantly fewer days with headaches and of less severity. That’s a result!
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thedysphoriadiaries · 11 months
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Entry 55 - 13 June 2023, 7:40pm
If you're reading this, I lied on my previous entry.
Regrettably, the last entry was not the final entry in this series.
There's been a thing that's been on my mind lately.
My friend sends me reels like these (or these) occasionally.
It makes me question my decision to align my body and brain's biochemistry with that of a natal female's, even if it were to ease the discomfort which I currently feel being in it.
As much as I understand that it's a joke, it still... washes me over with a tinge of sadness.
Is this what he expects of me?
As of this moment, he does not know about the existence of this series of entries (or the series of entries which I keep in my phone, to avoid the expression of my thoughts - through mediums such as this - from interfering with the correspondences which I have with others).
And for our sake, I hope he doesn't. Ever.
I am sick of staring into people's eyes, while drowning in the seas of my consciousness. I might as well be permanently drugged on some form of Paracetamol (or Panadol, or Tylenol, wherever you come from), just so that I begin to feel that this dissociation is normal.
I do not wish to keep drowning.
My father screams - one which signifies his failure to control his temper. I cannot afford to keep drowning.
...
A day has since passed since I last wrote the above.
And yes, it seems like this entry is not the last in the whole series, regrettably.
The razor glides over my skin, and even with the lubrication provided by the shaving cream, I feel the micro-lacerations caused by the blade gliding over the bumps in my skin where hair once was.
It hurts.
But the physical pain never holds a candle to the memories which my mind drags up during bathtime.
Things like the displeasure I have towards my own body.
Things like the random memories of me, and the females around me. They normally involve me looking at their features. The way the ponytails of my female classmates swished from side to side as we all ran the 2.4km run during the mandatory fitness tests. The way I looked at some of them and felt an inexplicable draw to them (or other feelings, which weren't exactly romantic in nature), or tested the system by growing my hair out as long as was permissible for the boys (to the point the disciplinary master told me to cut it).
The way I found female features so interesting that I'd feel more towards them than to the girls they were a part of.
But the worst memories are of me trying to be a girl. The way I remember the pictures that my ex-partner and I took of us sitting in a shade, with me trying to look as femme as possible - I still saw a man, trying to be a girl. I still remember the way I tried so fervently to run away from the masculinity which has been in my body for the longest time. The same masculinity which has allowed me to provide for my family. The same masculinity which allows me to do so over and over, without needing as much of a break as I would have required, if I was a girl.
They are the ones which make me whisper my apologies over and over in the shower.
...
I'm sorry.
I'm sorry.
I'm sorry.
Please.
...
And, as much as my friend tells me about how men are stronger, since they serve the country, or since they have to stand up for themselves, that is but one type of strength.
The time before the water touches my body is when the thinking gets the most intense.
What do I really want?
I feel the breadth of my ribcage, and realize that while it's not as narrow as I would like it to be (or compared to my ex-partner's), I recognize that it's mine.
I watch this reel, and wonder if the feelings I felt the whole time were just caused by an interest. After all, I was happy to provide for my partner. I was happy to provide for my family.
And, as someone said, my frame could hold a lot of muscle.
Yet, I remember how I'd cringe when my dad said that he bulked up quite a bit during his days serving in the army, and imagining myself like that too.
I remembering cringing at that someone who said that my frame could hold a lot of muscle too.
Why am I not enjoying being a guy as much as I should?
Am I broken for wanting (or not wanting) to be more like a girl, or a girl?
Am I broken for wanting (more like not wanting) to be like a guy, or a guy?
...
Too much of a guy to be a girl.
Too much of a girl to be a guy.
Would it kill me to just be human, in a society which places so much emphasis on gender?
Would it kill me to admit that I would rather have periods and complain about them to other people, or that I would rather have the innards of a natal female, instead of the thing between my legs?
It seems that, yes, it would.
And it's why, in a way, I still hold on to the part of me who's a boy. The boy who wanted to be a girl (it's still kinda what I see myself as).
...
But I know where I stand.
On a scale from guy me, to Lynn, I lie closer to Lynn.
Yet, as I look at the profile of my shadow on the door of my room, I wonder if it's something I really hate.
But that's a thought for another day - I still stand where I am, gone further than most sane cis people (at least, from my country) will, and yet, not as far as most trans people I know. I sit in the middle.
Two days to my next counsellor appointment.
There is a lot to talk about.
There is not enough time - Uncle Sam calls, and I know that the letter will eventually come. Maybe it'll show me what it means to be a man, maybe it'll push me further into my shell. Maybe it'll kill the girl inside for good. Maybe it'll give her the motivation to remove herself from the labyrinthian prison I have trapped her in.
But until then, I'll try to relish the freedom I have to think about my own condition.
I'm very much aware that this sort of time will never come again, in my life.
...
cool song time
kinda makes me wonder where I'll go in my next life. will I finally meet her? or be her?
nobody knows, and I take comfort in that.
maybe someday I'll know.
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lindsaywesker · 2 years
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Good morning! I hope you slept well and feel rested? Currently sitting at my desk, in my study, attired only in my blue towelling robe, enjoying my first cuppa of the day. Happy Hump Day!
I’m high as bloody kite! Still on the antibiotics for my cellulitis. Still pumping this evil stuff into my body four times a day! Listen, mate, I only take paracetamol in DIRE DIRE emergencies! So, my body is NOT used to all this drug use! I know some of you coke fiends are quite happy living on another planet but me, personally, I want to live in Harlesden. I quite like it here.
I forgot to tell you: I had a brilliant Sunday brunch with some of my old Highgate Wood friends. These are some guys who knew me when I was eleven! Can you imagine Lindsay at eleven? To be honest, I was exactly the same as I am now. Yes, really! I was the most precocious child you could ever have the misfortune to meet! You’d talk to eleven-year-old Lindsay and think, “How old is he?” I was analytical and philosophical even at that age. I wanted to know how everything worked!
Anyway, me and my mates had our traditional ‘four Yorkshiremen moment’, talking about how the kids of today don’t know how easy they’ve got it! Or have they? Have the kids of today really got it easy or is it an evolving and creeping nightmare that will eventually make them bitter and cynical? The kids of today have got no chance of owning a home, few have a chance of a decent job, few have a chance of a decent relationship, they have no clean air, no clean water, and the food they eat has about as much nutritious value as the plastic rice that crept on to the market a few years ago.
Have the kids of today got it easy or have they actually got very little future? Now there’s a depressing thought. When we die, how will they cope with all the toxic people out there? We’re struggling to cope with all the hypocrites, scam artists and crooks, hope will they cope?
And then me and my old school friends suddenly realised that, when you think about, growing up as a teen in the seventies and eighties was THE BEST! The best music, the best clothes, the best hair styles, the best clubs, the best dance moves, the best cars, the most iconic TV shows, the most iconic films. In those two decades (1970-1989) – my god! – how much fun did we all have? You know what happens when you get together with your old old school friends! The conversation always goes there: the good old days! You know that really good re-mix of Lou Rawls’ ‘You’ll Never Find Another Love Like Mine’? That just proves my point. Them tunes they made back in 1976 are still killing the dancefloor!
So, party people, while you’re out and about this weekend, strutting your stuff and flirting in a not very subtle manner, please think about my poor, weak drug-ravaged body. My idea of heaven is doing sod-all and having my leg elevated and, on Saturday night, that’s where I’ll be. A few of you will have both of your legs elevated but you’ll probably be having more fun than me! If you’re in good health, treasure it! Good health is priceless! Literally, priceless. You can’t buy good health; you have to take care of your body. Was that last cocktail necessary? Only you can answer that question.
Thanks for reading all the way to the bottom of my status. Many people don’t like reading. It’s too much hard work. So, I thank you for giving me five minutes of your day.
Have a wonderful and well-endowed Wednesday. I love you all. Yes, a crazy, bald (and very sick) man loves and cares about you.
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ironshadow6 · 2 years
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The Problem With Prescription Painkillers
Opiates are among the most addictive substances in the United States. Millions of prescriptions are written every year, with many people developing an addiction on just their prescribed dose. Learn about the different types of these drugs, their effects, and how they are most commonly abused and treated. If the medication is not working well, talk to your doctor. Take steps to improve PDMPs, such as real time data reporting and access, integration with electronic health records, proactive unsolicited reporting, incentives for provider use, and interoperability with other states. Prescribing only the quantity needed based on appropriate pain diagnosis. It can cause a life-threatening illness called Reye’s Syndrome. Topical nonsteroidal anti-inflammatory drugs provide pain relief in common conditions such as muscle sprains and overuse injuries. Since the side effects are also lesser, topical preparations could be preferred over oral medications in these conditions. Nervogen Pro that have been introduced for uses other than analgesics are also used in pain management. Both first-generation and newer antidepressants are used alongside NSAIDs and opioids for pain involving nerve damage and similar problems. Other agents directly potentiate the effects of analgesics, such as using hydroxyzine, promethazine, carisoprodol, or tripelennamine to increase the pain-killing ability of a given dose of opioid analgesic. Analgesics are frequently used in combination, such as the paracetamol and codeine preparations found in many non-prescription pain relievers. In contrast, doctors typically prescribe medication as a painkillers after an injury or surgery to relieve pain and avoid painkiller addiction. Yet, people can purchase prescription drugs without a prescription in illegal forms under street names. It’s absolutely outrageous that this doctor is advocating the use of tylenol for pain relief . Much research has proven that it works no better than placebo for pain relief…. I wonder why she would then prescribe it for elderly patients. She said it does not manage the pain as well as Lyrica, which she took for eight years. Opioids are addictive, NSAIDS are bad for the stomach and intestines and paracetamol is ineffective. The warnings about not using aspirin as an analgesic and the PM” versions of OTC meds. I read some of it to my wife and she responded with an, “Oh oh! ” A half hour later she came out with an amazing assortment of “PM” bottles to be disposed of.
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starthope5 · 2 years
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Painkillers Can Sometimes Increase Chronic Pain
I’m helping an elderly relative who is struggling with the pain of post-herpetic neuralgia after shingles. She takes a total of 500 mg of Gabapentin spread out in 3 doses (which doesn’t alleviate the pain but is concerned that more will have her sleeping all day). She was also advised to limit Tylenol to 2000mg daily-so she spreads out 3 doses of regular Tylenol in the day. As she tries to increase her activity level, the pain has increased and we wondered if maintaining the totals of each but playing with timing/dosage would help. For example, would it still be safe for her to take two extra-strength Tylenol twice a day to hit the pain harder but still keep to 2000 mg—or is that too much for an elderly person at one time? On average, women weigh less than men so these drugs have much higher effects on them than the average man. The correlation between the amount of pain medications available and the increased deaths of everyone, not just women, almost go hand in hand. Many medical conditions that affect people’s lives involve some type of chronic pain, whatever it may be. In today’s medical society, the prescription of drugs, more specifically painkillers, has almost become the first response to any and all conditions no matter the severity. So other options at pain management actually include cognitive behavioral therapy. In other words, helping you deal with how you appreciate that pain, how you respond to that pain. It also includes access to her popular Helping Older Parents Course and live QA calls with her. Medrol is a powerful anti-inflammatory steroid, and a form of steroid can also be injected directly into the joint which is often the way it’s used in a rotator cuff tear. Some types of rotator cuff injury require a surgical repair unfortunately. I haven’t hears of that before but I think “panadol” is also known as paracetamol, which is the same as Tylenol , so you could consider it as being similar to the acetaminophen discussed in the article. Still, the patches are safe, says the FDA, when prescribed to the proper patients — those who have been taking daily opioid medications for chronic pain. That's not to say every prescription painkiller is bad; quite the opposite. But take too many painkillers, or combine them with potent sedatives — as actor Heath Ledger did in 2008 — and they can be fatal. Unfortunately, painkillers aren’t without their fair share of risks. And when speaking specifically about My Back Pain Coach like OxyContin or Percocet, painkillers can have very negative effects on your body. In this article, we’ll review how pain pills work and discuss the long-term effects painkillers can have on the body. Yet many current and former players interviewed by ESPN said it was commonplace for players to get prescription painkillers from sources outside of NFL locker rooms, either from unscrupulous doctors or drug dealers.
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sidhiroy · 2 years
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Plan Your Ladakh Trip 2022-capture a trip
We see that you’ve clicked on this blog, and that means you’re planning your Ladakh package plan to go to Ladakh soon. Ladakh is the trending destination of 2022 and we can understand why you’ve planned to go to Ladakh this year. But realistically speaking, for many people, Ladakh doesn’t turn out to be as happy and wonderful of an experience as they think of it to be. The reason behind it is simple, and that is opting for a bike trip to Ladakh without much preparation and research.
 So, this blog is to help you with basic DO’s and DON’Ts to make your 2022 Ladakh trip the best experience.
 1. Deciding the Route
Ladakh is a destination that is all about its roads. After all, it is always a “Ladakh tour package” and never just a trip to Ladakh. There are various routes of Ladakh from different locations and they all come with their set of difficulties and joys. Capture A Trip provides the Ladakh road trips with four different routes and we’d like you to research thoroughly about each of them and then decide the correct mix of adventure and comfort that a certain route will provide to you. This is the most basic thing that you should keep in mind before planning your Ladakh road trip and a in-depth research is needed for this.
 2. The Right Bike
Definitely deciding the chosen route, the next that should come to ones mind is choosing the right bike. You’ll be travelling through the toughest of roads and choosing the suitable bike for a trip that is 10 days long is a crucial task. There are many bikes available in the market, some of them are Royal Enfield 350C, Enfield Bullet, Pulsar bikes and so much more. Along with available bikes, it is also important to carry the right gears, back rest, ropes to tie your bags from the bike etc. Try to ensure that you carry all the necessary equipments with you and before going on the trip, make sure that your bike is serviced and does not cause you any trouble during your journey.
 3. The Right Season
So, let’s talk the real topic- the best season for travelling to Ladakh. If you’re going on a Ladakh bike trip it is advisable to go for the season of summer I.e Mid-May to Mid-October. In the winter, roads are blocked due to heavy snowfall and are not safe for going on a Ladakh road trip.
 4. Fighting that AMS (Altitude Mountain Sickness)
Dizziness on the curvy roads of Ladakh is very common, but on a long trip it can suck the joy of travelling and exploring out of you. It is always advised to take all your health conditions in mind and carry precautionary medications along with you. Generally Avomine is recommended to fight AMS in the mountains and some other basic medicines like Paracetamol, Crocin and Volini etc are recommended to take along with you.
 5. Say No to Alcohol and Smoking Up
Keep in mind that it is Ladakh and not Manali and Kasol. The roads are 10 times more dangerous and you will not like to take a risk. You should refrain from the consumption of Alcohol and other drugs and should try to be in your senses as much as you can. Instead it is recommended to carry energy drinks and caffeine with you to stay awake and focussed on the road.
 These were some of the most important things to keep in mind while you go on your Ladakh group tour. Along with these do not forget to take frequent halts on the way and keep yourself relaxed, carry extra petrol and keep necessary things like some snacks to munch on, band aids, warm clothes handy.
 With this, we wish you all the best and enjoy your Ladakh road trip, because as it is said 2022 is the year of LADAKH!!
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sayabenz · 2 years
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*takes a codeine pill for my headache*: is this what being high feels like?
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somecunttookmyurl · 3 years
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Hi sorry to bother you, but I just saw your post about not metabolising medication properly, I was trying to track back to any other mention of it on your blog to find out more because that is ringing a lot of bells with me and I didn't know it was a thing that could happen (I'm not jumping to conclusions I'm just curious), I'm chronically impossible to medicate (presumably what you mean by "Drug Goblin") so I was wondering if you could point me in the direction of the specific thing you're talking about? I tried doing straight to ye olde Google but without a decent starting point I just get vague anecdotal articles </3
oh no worries about not finding it i never tag anything and tumblr's search function is an eldrich horror that's not on you in the slightest
the basics of it (this is very simplified and i'm happy to send papers but they are like. pretty technical which involves "learning what all the words mean first")
- there's a bunch of different enzyme pathways in the liver. just so many.
- different drugs will be processed along different pathways. most drugs only go one way, but some take multiple routes and split off. paracetamol (acetiminophin) for example uses... iirc... three? so some of it goes there, some goes there, and some fucks off over there.
- the normal amount of functional copies of any of these things is 2. and 2 is what the vast majority of people have. if you've got 2 copies then the drugs that ride that highway work broadly as expected. like you know all the "starts working in x time, lasts this long" stuff? based on the normal range
- for any given one of those, it's possible to have 1 (or even 0) functional copies, or 3 (or more) copies. if you have fewer functional copies then your metabolism is slower. the drug sticks around longer, and will have a more pronounced effect. as such, you would need a lower dose. also your toxic dose level would be lower
- if you have 3 (or more) you metabolise faster. as i'm sure you can guess, that means it's processed too quickly and there is less effect because it's been yeeted out at the speed of sound. you need higher doses, administered more often. which is problematic for your poor kidneys who regrettably still have to deal with it.
- all of these enzymes can be either inhibited (metabolism slowed) or induced (metabolism sped up) by various substances. this is, primarily, what drug interaction warnings are. if drug a is inhibiting the enzyme used by drug b, you could have a problem on your hands
- for most though that list is pretty extensive! as such "defects" on most of them don't really go noticed so much because you're probably fixing it by accident by, like, drinking coffee or whatever
- however Local Problematic Bastard known as P450 CYP2D6 (i know. super catchy) is almost entirely genetic - meaning the list of external things that can either inhibit or induce it is fucking tiny
- unfortunately, Local Problematic Bastard P450 CYP2D6 is where an awful lot of very common drugs like to hang out. so if you've got too many functional copies of it there's a whole bunch of shit that Don't Work So Good and your ability to fix it is, uh, limited
- in the general population being an ultra-rapid metaboliser is pretty uncommon. worldwide it's something like 7% and in white people it's 1-2%. however for reasons that are still unclear, people with chronic pain (notably EDS but also stuff like fibromyalgia) have a frankly stupid 70-80% chance of something in there being broken in some way
- which is a fucking cruel joke bc Most Goddamn Painkillers chill on CYP2D6 If you look up CYP2D6 on wiki there's an (incomplete) list of substrates, inhibitors, and inducers. substrates are the drugs that are metabolised along it. if you read the substrate list like "wait a minute... this is all the shit that doesn't fucking work unless i practically OD on purpose" then my apologies but also same and i hate it
anyway a while back i had the thought "what if i added an inhibitor to biohack my own goddamn liver and make it talk to meth properly" which i studied with CBD (one of the few inihibitors that aren't obscure prescription drugs) and spoiler alert: yes. yes you fuckin' can. (i did research this extensively before trying and human studies on the exact same theory have been done before and the results were positive in all but one person, and that's only because that person had an adverse side effects to the inhibitor and had to drop out)
this is something that can only be properly officially verified with a genetic test but sometimes shit be So Blatantly Obvious you don't need to prove it.
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tenthgrove · 3 years
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500 Followers Celebration!!!: Part 2 (Yandere Sorbet and Gelato Oneshot)
Apologies for almost forgetting to post this. It's a little something I wrote back in May but never shared with more than a few people. Anyway, I'm shameless, and to celebrate 500 followers I'm releasing it into the wild.
Content warnings: non-consensual drug use, needles (both only mentioned) and typical yandere stuff.
You aren’t certain what the dream was about. It wasn’t a nightmare, you’re certain, but the concrete themes evade you. What you can remember in retrospect, however, is the distinct feeling that something was wrong in the waking world around you. It was as though your rational mind knew, that when the dream ended, the life you would wake up to would be changed irreparably.
The first thing to be said about the room you awake to is that it’s dark. Not the usual dark of your bedroom at night but truly, pitch black. There’s something different about the… aura, as well. Maybe it’s the scent, maybe it’s the feel of your sheets, maybe its the position you’re lying in. This is not your bed.
Your panic rises by the second. Any hope you might still be dreaming is quickly put down to idle hope. Everything about this feels so real. You are struck by the need to get up, to figure out where you are, and kick off the sheets. That’s when you hear rattling. Your arm is heavy. You reach down and feel the cold presence of limp chain at your side. There’s a shackle too, locked around your wrist with no room to wriggle free. If there’s any more proof you needed of what’s happened to you, this is it.
The panic overtakes you. You thrash desperately, pulling at your chain and whimpering in terror. There’s a clicking noise and something pulls free. You become aware of a second item tied around your wrist. It’s a thin string, with nothing attached. You realise with terror that it was some sort of trip-wire.
All possible courses of action spring to your mind too late as footsteps make their way down towards you. There’s multiple people, it sounds like, which doesn’t speak well for your chances. Bundling up your sheets, you huddle against the wall as the door swings open. A light switch flicks on.
As your dark-strained eyes adjust to the light, you are met with the figures of two men. The first, hand still lingering on the switch as he eyes you back, is a slender, dark-dressed man with black hair to match his clothes. The man beside him is smaller and slightly pudgier. His wild green eyes peak out from under his messy yellow hair. His gaze fixes on you, before dissolving into an expression that could be fear, excitement or both. He suddenly lurches forwards. His hands grip your shoulders firmly.
“Oh, look at you!” he coos. You force yourself to meet his gaze and see the wildness with which he looks at you. “Oh Sorbet, aren’t they pretty! Look at them Sorbet, they’re just wonderful!” The hyperactive man stumbles back as though wanting to get a better look at you. His hand is clasped over his mouth like you’re some puppy he just found at the shelter. The taller man takes hold of him from behind and rubs his arms affectionately. His mouth turns up into a small smile.
“Yes my darling, they’re beautiful,” he agrees. “But you shouldn’t touch them just yet. They might still be delirious from the drugs. All said,” he eyes you critically. “They shouldn’t be awake this soon.”
“Does it hurt sweetie?” his partner asks. There’s an uncanny, authentic concern to question that somehow turns your stomach more.
“N-no,” you stammer, keeping your eyes trained on the concrete floor. Truth be told, you’ve got a bit of a headache and the back of your throat pangs with nausea, but it isn’t bad enough to tell them. You decide to keep it to yourself.
“Did you give them that second dose in the end, Gelato?” the calmer man, you believe his name was Sorbet, asks. He approaches you casually and kneels down, pressing a hand to your forehead. “No fever anyway, so it doesn’t look like there’s been a reaction.”
“No. You said not to do it if they seemed fast asleep enough, so I didn’t,” Gelato answers.
“Well, there you have it then,” Sorbet says, apparently satisfied of your good health as he stands back up.
“I could always go find some more of the stuff. If you need more time to get everything ready for them,” Gelato proposes. Sorbet’s eyes flick up and down you as though contemplating what to do with you. He shrugs.
“Probably best to save it. I’d say we’ve already done everything we need to do, so they might as well stay awake for a bit,” he surmises. “Well.” He reaches forward and presses something, a key, you realise when you lean back far enough to look, into a slot on the grate attaching your chain to the wall. It falls free of the wall and chinks onto the ground.
Sorbet leans down again. You realise with a cold sweat that he’s trying to pick you up. Your attempts to scurry into the corner are quickly halted by a sharp yank to your chain, and a moment later you’re lifted against Sorbet’s chest, your faced pressed into the crook of his neck. “Could you please do the door for me, Gel? I’m taking them to the bathroom.” he asks. Gelato mutters something eager and hurries off to open the door from him. You struggle lightly in Sorbet’s hold and he silently presses two fingers against your neck. You take the warning and go still in fear.
Sorbet carries you up a flight of stairs and into the hall of, by all appearances, an ordinary residential house. It’s night, but a warm yellow ceiling lamp sheds light on your surroundings. The walls are a pale, turquoise green, accented by a white wood skirting that runs along the bottom metre. To your left you can see an archway into a clean but cluttered kitchen, lights off, and another staircase is ahead of you bending around to your right. To your right, along the hallway you’ve been carried into, are two more doors, one at the end and one perpendicular to it, the latter of which Sorbet leads you into. Peering over his shoulder, Gelato follows behind you. He catches your gaze and smiles sweetly. You quickly look down at the floor.
Sorbet flicks another switch and another light turns on, along with the gentle humming of ventilation. You adjust your eyes to see that you’re in a small, downstairs bathroom. Furnished with a toilet, sink and shower. Sorbet sits you down on the lid of the toilet and kneels down in front of you.
“You look disorientated. Are you sure you aren’t in any pain?” he asks.
“Just a little,” you admit. Your words a little slurred. “My head hurts. ‘Feel sick too.”
Sorbet sighs.
“You should have told us, (y/n),” he asserts, a hint of frustration, in his voice. That was your name. They know your name somehow. You mumble an apology.
“Oh darling. I’ll have to get you some paracetamol. You really should have said! Oh, and also a bucket for if you get sick in the night. Maybe some ice?”
As Gelato rambles from the doorway, Sorbet pulls a pack of wipes from the sink cabinet and starts to pat down your arms, wiping away the layer of crusted blood. Your heart stills. You didn’t notice that before.
“Why is there blood?” you ask weakly, eyes fixed on the sight. Sorbet dabs away at what appears to be the centre of the wound. His free hand rubs your knuckles slightly.
“You fought back, don’t you remember? Some defensive damage was inevitable,” he answers you.
“No!” you refute, louder than you intended. “I don’t remember anything like that. I don’t know howI got here.”
“Ah,” Sorbet responds. “I imagine that’s from what we gave you,” he explains. A few images flash across the back of your mind. Broken glass. Screaming, fighting. The feeling of being pinned to the floor. Your stomach twitches and you swallow back tears.
“What’s the matter sweetie? You look sad,” Gelato notices. No shit you’re sad. You’ve just been snatched from your home and yet to receive any guarantee you’ll live until morning. There’s a part of you that wants to scream these thoughts to them, but you’re too paralysed by fear and tiredness to do so. The tears start to run.
“Oh darling, darling!” Gelato hushes you, rushing over to wipe your eyes. “Don’t cry, it’s okay! We’re going to look after you!”
“Caro, you’re very good to them but I doubt any of that will work right now. They’re too worked up,” Sorbet notes. You sob into your lap as Gelato caresses your shoulder.
“We can’t just leave them like this, Sorbet. Not alone,” he shivers.
“Perhaps you’re right. Maybe it’s best we put them out again after all. We’ll be better ready to deal with this in the morning,” Sorbet suggests.
“Yes, that’s probably for the best, come on Sweetie, let’s get you back to bed shall we?” Gelato takes your chain and starts to haul you back towards the stairs to the basement, with Sorbet following close behind. When the dark of the basement hits you again, you’re just about ready to fall asleep, but you’re still aware enough to note the peculiar furnishings you missed before.
The mattress you woke up on is tucked away in the corner, swarmed with cushions, pillows and blankets. There’s a small cabinet next to it, along with a table a few feet away with a TV on it. On the other end of the room is a mini-fridge, next to a large empty case of shelves. Are those all… for you?
Gelato guides you to sit down on the mattress, wrapping a blanket around you and fluffing up a pillow as though trying to get you to lie down. As he does so, you’re vaguely aware of Sorbet slotting your chain back into the wall and locking it in place. He looks you up and down again, for a moment seeming to fixate on the stream of tears that run down your cheeks.
“I’m going to go for a minute now. I’ll come back with something to help you sleep. Is that okay, hmm?”
You nod weakly. Honestly, you’re so insanely terrified right now, that falling asleep truly sounds like the better option even if it renders you at their mercy. Sorbet adjusts the blanket around you.
“Alright, sit tight sweetheart. I’ll be back in just a moment,” he promises. He leaves you alone with Gelato. For a moment, the second man is quiet, a hint of something in his eyes that looks like sadness. He sits down next to you and rubs your fingers.
“I’ll stay with you until he comes back, okay?” he offers. You give a quiet hum of acknowledgement, staring straight ahead as your mind starts to dissociate. “It’s really nothing to worry about,” Gelato says. “Just a tiny prick in your arm and then you fall asleep in a few minutes. You’ve done it before, anyway, and we won’t give you so much this time.”
You don’t answer him. He goes still for a little, perhaps unsure of what to say, then pulls you in close against his shoulder. “You’re wonderful,” he tells you.
“Why are you doing this?” you ask him faintly.
“Because we love you.”
“Why?” you implore him. Before he can answer that you fall into renewed tears. Gelato’s voice seems to fade away from you as he frantically tries to calm you. You shut your eyes and hope for this to end. Whatever this is. You’re scared, and you just want to go home. You just want to stop this feeling of fear.
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why
what are you doing
i wonder what you're doing, i wonder how you are. i wish i could stay close to you, i wish you'd answer me. what's my drug of choice? paracetamol and ibuprofen, herbs, warmth, a weighted blanket and the thought of you.
oh my fucking god, how am i supposed to sleep with you on my mind?
well, what have you got?
well, what's on your mind?
im terrible at hiding my emotions, everyone can see that i cant think today. i can't think of anything, i don't understand why you're pushing me away.
im not gonna give up on you
i dont wanna live forever tormented by my own cowardy
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