#Stop IGM

[mxanunnakiraymarquez]

Some People in Power and Control Will Not Stop Regulating Our Intersex Lives as Nonconsenting Children.

My educational thoughts for the day: We have all been taught by colonialism, and people in power and control, to pathologize human diversity. This language mostly comes from people of power who are white, endosex, cisgender, heterosexual men. To this day, people in power and control invent what is “normal” and have judged, pathologized, and diagnosed human diversity. They invented racism, the…

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#Colonialism #Cosmetic Genital Surgery #Cultural Dysphoria #End Cultural Dysphoria #End Intersex Surgery Now #Government #Government Officials #Human Rights #Intersex #Intersex Awareness #Language Matters #Prejudice #Self-Determination #Stop IGM

[identitty-dickruption]

hey dyadic people. you do know you're allowed to NOT mention genitals in the notes EVERY single post about being intersex/intersexism, right?

you do not need to bring up genital mutilation when a post is talking about a completely different form of intersexism. you do not need to bring up how fascinating our bodies are when a post is about intersex positivity. you do not need to ask intersex strangers what their genitals are. you do not need to do this shit

please. I am begging you. see intersex people as more than our genitals. see intersex people as more than our medical trauma. obviously genital differences and medical traumas are real parts of the intersex experience, but it cannot be the only context you can ever bring yourself to see us in. see us as real human beings

#sick of the fact that every single post I've made about being intersex is FLOODED with shit about IGM #do you not realise how traumatic that is #do you not realise that I don't always want to talk about it #do you realise that intersexism is more complex than that #stop it. for real #intersex

[transmascissues]

as an intersex woman- it'd be real nice if these people stopped throwing around the word "mutilation" and ignoring IGM (which is still practiced en mass even in "first world" countries) and our lack of bodily autonomy. a trans person (or even a cis person getting elective reconstructive surgery for a myriad of reasons, including IGM) getting bottom surgery is in no way comparable to actual mutilation against your will and it's such a slap in the face to see these people bitch about it while ignoring us. our medical records are literally hidden, destroyed, and altered for the sake of non-intersex people never having to contend with the reality of sex variations.

I bet they'd probably look at the stats on Intersex human rights and try to justify it away though, they sound like the types who want Intersex people to fit into their two perfect sex and gender boxes and never complain! thank you for not backing down, muddying the waters on mutilation- while the intersex community is still trying to fight to get IGM recognized and banned- harms IGM victims worldwide and disgusts me to my core.

Not to mention how many recent american bills banning or limiting elective trans surgeries conveniently still allow for IGM and the pushing of hormones on intersex children and adults who don't need them (again for the comfort of non-intersex people and the assumption we must be "fixed"...) very convenient for these people to ignore!

all of this! these people will act like the “western world” was totally against genital mutilation practices until the big bad trans people came along, when in reality it’s been happening right here at home the whole time.

the only reason they don’t see it (or at least act like they don’t see it) is because of intersexism and racism — intersexism that tells them that whatever’s being done to intersex people must be beneficial and medically sound because of course intersex traits should be “fixed”, and racism that validates their belief that the things happening where they live must be better than what’s happening “over there” because of course there are more human rights abuses happening in non-western places than in their good progressive home.

fearmongering about anything that changes the clitoris or vulva in any way being a form of FGM + downplaying the harms of IGM and saying it’s just good medicine = the perfect way to uphold their precious pseudoscientific sex binary for another day, i guess. as long as we’re all living with the genitals they think we should have, they don’t care who it hurts.

#ask answered #transandrophobia adjacent issues #intersexism #interphobia

[appalachiananarchist]

My immunoglobulins have been on a steady downward trend and I am worried I'll have to stop rituxan in the near future because of it. My IgM is down much lower than before, though IgG is holding steady. Rituxan has given me so much of my life back when little else was working, so the thought of losing it is upsetting. I don't have to worry quite yet, though. I don't think they are low enough to stop my infusion next week. My WBCs are actually pretty good at 3, though my neutrophils and lymphocytes are still down.

I just hate that my condition, if untreated, causes me to have concerningly low white cells/neutropenia The treatment for my condition, which makes those numbers a little better, messes with the Ig levels. There is no way out of this that doesn't involve my immune system taking a hit.

My platelets and RBCs are good though! I've been bruising a lot so I was worried about the platelets, but we're all good. Kidneys are also being troopers as always. Major shout out to my kidneys, which have weathered everything like champs.

#i will be having a stern talking to my lungs though #for crimes against my wellbeing

[kes-geiszler]

just saw an article about banning intersex genital mutilation (good!!!) as a reason to ban all trans surgeries (bad!!!). IGM is an abhorrent form of taking away bodily autonomy!! and do you know what else is? removing trans peoples ability to get access to gender affirming care. I need transphobes to stop using intersex people as a shield for their transphobia and fascism.

#intersex #trans #transgender #important

[ninootny]

talk about gary the gadget guy i am listening very intently

ninoo and gary documentary

"a flabbergasting and beautiful story about a kid who learned nerd exists" 8/10, -igm

"my favorite fanfiction, wait, it's a documentary? even better!!!" 10/10 - club penguin times

gary is like so special just look at him he's so tiny idk, he's a friend!!! i wish i was able to get gary stuff when i was younger but i never found club penguin stuff in stores (even if it was pretty popular in france) he really did something to my brain when i was playing club penguin everyday back then (at least when i was at my mom's place/work because for some reasons (child of divorce) i became chronically online around 8). i would just do on loop the psa missions because i loved him, and my dad put the club penguin epf ds game on my r4 and yeah, obsessed.

since i'm (breaking my silence) i'm a nerd i think i related to him + he has glasses + he's creative, i just had a huge kin moment i think. I stopped playing club penguin after operation blackout, and then i came back a few years later with a few friends because we were going on every old kid mmo to have fun (we were roleplaying/trolling in a nice way, like we were just like "we're about to hack the epf silly penguins.... and steal all your pokemons" (because pokemon go was popular and we loved it a lot) and i saw him again. and i was remembering how much i love that guy. i would love to find my old drawings of him but i moved a lot sooo a lot of drawing are lost-

i remember when they announced island i didn't understand club penguin would shut down. and I didn't saw the website closed, I learned it maybe a week after the terrible event and I was devastated. my friends from this era didn't care a lot about it because they never played to club penguin when they were kids, i cried about club penguin shut down and not being able to see my silly penguin again (Nella02, a cyan penguin who never got the membership because my parents were broken af if I remember well when i was a kid), but also, not being able to play the legit version of club penguin and knowing I'll never get new EPF events, no more gary content.

the void

but hey!! we can find some!!! tweets!!! from my new twitter acc because the old one is gone (got banned for lying about my age)

after this event gary just came back in my head sometimes and i would be crazy for like. a week maybe.

"love"

but this time it's getting very long, i really want to focus on other characters like Cadence and Rookie because i loved them too as a kid (I wanted to cut my hair very short but my parents were pretty much against it because they were like "you need to keep girly long hair" 💀 and seeing Cadence as a kid made me happy I think) but gary is too strong idk

in 2020 i thought about rookie and gary at the same time it's crazy

"clearly the best huh"

"i really want to play to club penguin but i'm at work" (heartbreaking)

also i think it's because of him that all my favs are blue pathetic nerds that never sleep (tsumugi aoba from ensemble stars my dearest wife)

"gary from club penguin i think about him evry day of my life amen hes just the type of person i love sorry blue nice pathetic nerd who wants to be useful to others"

"its the saem character"

sorry i needed to talk about my relation with club penguin and i think in a few years i'll just. i'll just look like my gary gijinka. my hair are blue and i really want a lab coat BECAUSE OF THEM ALL

have a nice and beautiful day

#ninoo ask

[intersex-support]

idk how much y’all have heard about this, but Australia’s ACT government has drafted a bill “Variations in Sex Characteristics (Restricted Medical Treatment) Bill 2022” that would codify intersex people’s right to not receive medical intervention such as surgeries without consent, including for intersex children. Individuals can submit responses via an online questionnaire, and the deadline is Friday, 8 July, 2022.

https://www.cmtedd.act.gov.au/policystrategic/the-office-of-lgbtiq-affairs/variations-in-sex-characteristics-bill

This is really interesting! It looks like they have been working pretty closely with IHRA to draft these proposed legal reforms. I have not looked through it super carefully yet, but it looks like it is trying to put up a lot of barriers to stop IGM from happening to children. It does not totally ban it, but I personally think these reforms are a good harm reduction method.

It is open for public comment by people from any country, so I strongly encourage intersex people and allies to leave a comment in support of this bill/leave feedback on where you think it could be improved!

#thanks for sharing!! #mod e

[citrusitonit]

MOONY IGM SO SORRY IGL STOP SAYGON DEEH NUHS NOWG PSASE

[eonepay]

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#GPS Asset Tracker #Export General Manifest [EGM] #Import General Manifest (IGM)

[yourpreciousrose]

Stop IGM

people are more concerned about trans people who give consent than about intersex people who are forced to have our bodies f*cked with.

(do not share on other platforms without my permission)

#intersex #lgbtqia #intersex awareness #intersex rights #lgbtq community #queer #queer community #intersex awareness day #intersex community #intersex pride

[mxanunnakiraymarquez]

Poem: I am Whole and Unmutilated!

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#Human Rights #Intersex #Intersex Awareness #Intersex Awareness Day #My Body My Choice #My Intersex Story #Poems #Stop IGM

[identitty-dickruption]

the other thing you lot need to keep in mind is that being intersex isn’t entirely about genitalia, and many intersex people have roughly “normal-looking” genitals

when people talk about our bodies, a lot of the time they’re still using the fetishised version of the intersex body. they’re still thinking of us as having both a fully functioning penis and a fully functioning vagina, and that’s just NOT the case

yes, it’s possible for intersex people to have genital differences, but even then. it’s the least interesting part of my intersex experience. when you choose to just focus on the genitals, you’re forgetting:

the trauma that often happens to those of us with genital differences (e.g. IGM)

the hormonal differences (which can also result in medical trauma, as well as bullying and shame)

the resulting and/or comorbid chronic illnesses that often come about due to being intersex

being intersex is not 100% traumatic or anything. I actually have come to love my intersex body and my intersex community. but for all that is holy. please stop acting like being intersex is just “cool quirky genitals”

#intersex #intersexism #tw medical trauma #tw igm #pride #queer

[medicaregate]

Wiskott-Aldrich Syndrome | Causes, Symptoms & Treatments

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency that is characterized by eczema, recurrent infections, and micro-thrombocytopenia.

Wiskott-Aldrich syndrome is caused by an X-linked genetic defect in the WAS gene, which is located on short arm of the X-chromosome at Xp 11.22-23 position.

The gene product Wiskott-Aldrich protein (WASp) is a 502 amino acid protein that is expressed in the cytoplasm of non-erythroid hematopoietic cells.

More than 300 gene mutations have been identified that result in abnormal protein configuration.

Wiskott-Aldrich syndrome is caused by mutations in the gene WASP (WAS protein), which is involved in actin polymerization, cellular signaling, cytoskeletal rearrangement, and immunological synapse formation.

Individuals with the disease may experience a different number and severity of symptoms.

Bleeding

Immunodeficiency

Eczema

Autoimmune Manifestations

Malignancies

There are three main clinical phenotypic symptoms: –

Classic (severe) Wiskott-Aldrich syndrome

X-linked Neutropenia (XLN)

X-linked Thrombocytopenia (XLT)

Any male with thrombocytopenia, eczema, recurrent respiratory infections, autoimmunity should be evaluated for WAS.

Any male patient with severe congenital neutropenia should be evaluated for XLN.

Abnormal immunologic findings in patients with WAS include: –

Decrease number and function of T cells and regulatory T cells.

Abnormal immunoglobulin (Ig) isotypes.

Defective antigen-antibody response.

Impaired cytotoxicity of natural killer cells with normal to increased cell numbers.

Impaired chemotaxis of neutrophils and phagocytic cells.

Absolute lymphocyte counts are typically normal during infancy, but T and B cell counts decline later in life in people with classic WAS.

Variations in Ig levels, including normal serum IgG levels, decreasing IgM levels, and elevated IgA and IgE levels.

Wiskott-Aldrich syndrome is primarily managed with supportive care, which includes the following: –

Broad-spectrum antibiotics for bacterial infections.

Antivirals/antifungals for viral and fungal infections respectively.

Platelet transfusions to prevent bleeding.

Topical steroids to treat eczema.

Patients with significant antibody deficiency who have WAS or XLT should receive intravenous immunoglobin (IVIG) therapy.

Immunosuppressive therapy may be required for autoimmune manifestations.

In some patients, an elective splenectomy has been suggested as a way to stop the bleeding tendency and reverse the thrombocytopenia by increasing the number of circulating platelets.

HCT is the only available curative treatment.

Gene therapy is a potential alternative treatment for WAS that is currently being researched.

Read more at : https://medicaregate.com/wiskott-aldrich-syndrome-causes-symptoms-treatments/

#immune system diseases #rare diseases #Wiskott-Aldrich Syndrome

[orange1896]

13023391 4110000054243 WEICHAI Valve steam seal

13023391 4110000054243 WEICHAI Valve steam seal

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#WEICHAI

[kjerebbesen93]

Canopy panels syndication and also microclimate tastes associated with clean and sterile as well as untamed Qld fresh fruit jigs.

Background Profitable microcirculatory reperfusion, described angiographically through MBG A few, is a member of improved final results throughout sufferers together with ST-segment elevation myocardial infarction. The particular procedure main this organization isn't well described. Methods The INFUSE-AMI tryout randomized 452 sufferers together with anterior ST-segment height myocardial infarction for you to intracoronary bolus abciximab provided locally at the infarct lesion as opposed to absolutely no abciximab, and also to guide book thrombus aspiration vs . absolutely no faith. The key endpoint had been Will be (percentage of left ventricular muscle size) with Thirty days. Results MBG 2/3 was accomplished inside 367 individuals (Seventy eight.4%). Will be had been drastically reduced individuals together with MBG 2/3 in comparison to individuals with MBG 0/1 (typical: 07.7% [interquartile range (IQR): Several.2 to Twenty two.7] compared to. Twenty.5% [IQR: Eleven.One particular for you to 29.2]; g = 3.002). Intracoronary abciximab additional decreased Is people using MBG 2/3 (average: 14.4% [IQR: 5.4 to twenty.9] vs. 18.4% [IQR: 15.Five to Twenty three.8]; s Equates to 0.10). MBG 2/3 was linked to just like 30% decline in infarct size (g Equals 2.002) and other alike to 90% lowering of microvascular blockage about day Your five. Ejection small percentage was increased together with MBG 2/3 at 30 days: mean: 55 Selleck Muramyl dipeptide .3% (IQR: Forty three.8 in order to Fifty seven.Eight) as opposed to Forty six.9% (IQR: Thirty-seven.Five to Fifty-four.0); r = 3.004. From 30 days, the interest rate associated with loss of life has been considerably lower (1.7% compared to. 8-10.3%; r Equals Zero.0008) within the MBG 2/3 class. Conclusions MBG 2/3 occur in 80% associated with ST-segment level myocardial infarction individuals addressed with main percutaneous coronary intervention which is connected with smaller sized infarct size, a smaller amount microvascular obstructions, increased ejection portion, as well as substantially reduce 30-day death. (Intracoronary Abciximab and also Desire Thrombectomy throughout Individuals Along with Big Anterior Myocardial Infarction [INFUSE-AMI]; NCT00976521) (chemical) 2013 from the American School associated with Cardiology BaseThe options associated with 2 babies which in fact had clinical symptoms involving congenital cytomegalovirus have already been shown the following, whose CMV-DNA was discovered to become good from the PCR strategy, even with serological examination getting damaging with regard to CMV IgM. In conclusion, any time congenital CMV an infection is assumed throughout children, it shouldn't end up being forgotten about the sensitivity of serological CMV IgM analysis is 70% along with other methods such as CMV-DNA analysis needs to be carried out in the event of damaging analyze results.Cervical cancers disproportionately influences those in reduce socio-economic groupings. Advertising, such as newspaper publishers, are generally a significant resource about ailment and the way to avoid it. A great examination involving British countrywide newspaper articles between 2000 as well as '09 is described, evaluating the degree this agreement info is presented regarding earlier signs, risk factors as well as means of stopping cervical cancers. The actual emails in papers directed at audience inside decrease socio-economic groupings tend to be in contrast to your messages in other newspaper publishers, as well as the influence involving reporting the sickness as well as loss of life in the actuality Television set celebrity, Jade massage beds Goody, on the degree of health-related information found in posts will be evaluated.

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Dengue IgG/IgM Rapid Test

Intended Use

The dengue fever ELISA test is a qualitative enzyme immunoassay for the detection of antibodies to dengue, in samples of human serum or plasma. This test is intended to be performed by trained medical technologists only.

Assay Principle

The microwells are coated with purified dengue virus antigen from cell-cultured type 1-4 dengue. During the first incubation with the diluted patients sera, any antibodies which are reactive with the antigen will bind to the coated wells. After washing to remove the rest of the sample, the Enzyme Conjugate is added. If antibodies have been bound to the wells, the Enzyme Conjugate will then bind to these antibodies. After another series of washes, a chromogen (tetramethylbenzidine or TMB) is added. If the Enzyme Conjugate is present, the peroxidase will catalyze a reaction that consumes the peroxide and turns the chromogen from clear to blue. The addition of the Stop Solution ends the reaction and turns the blue color to a bright yellow color. The reaction may then be read visually or with an ELISA reader.

Intended Use of Dengue IgG/IgM Rapid Test

Dengue Fever Rapid IgG/IgM is an immunochromatographic assay designed for the qualitative detection and differentiation of specific IgM and IgG antibodies to dengue virus in human serum or plasma. It is intended to be used as in vitro diagnostic of dengue fever. The test provides a differential detection of anti-dengue IgM and anti-dengue-IgG antibodies and can be used for the presumptive distinction between a primary and secondary dengue infection. The results obtained should not be the sole determinant for clinical decision.

Summary And Explanation of Dengue IgG/IgM Rapid Test

Dengue virus, a virus belonging to the Flavavirus group of viruses, is one of the most significant mosquito-borne diseases in the world in terms of morbidity and mortality. Transmitted principally by the mosquito types Aedes aegypti and Aedes albopictus, the virus is found commonly throughout the tropic and sub-tropic regions of the world. There are four known serotypes of dengue. Symptoms of dengue fever include high fever, headache, muscle pain and skin rash. The complications often associated with this infection are dengue hemorrhagic fever or dengue shock syndrome.

Principle of Dengue IgG/IgM Rapid Test

The Dengue Fever Rapid IgG/IgM is an indirect solid-phase immunochromatographic assay. Serum or plasma samples may be used with this test.

When a specimen is added to the test device, IgG and IgM antibodies in the specimen sample, if present, will react with particles coated with dengue envelope proteins to form a complex. As this complex migrates along the length of the cellulose nitrate membrane, the anti-dengue IgG or IgM antibody particle complex is captured by the relevant IgG and/or IgM test bands located in the test device window causing a pale to dark pink purplish band to form at the IgG or IgM region of the test device window.

The intensity of the bands will vary depending upon the amount of antibody present in the sample. The appearance of any color in a specific test region (IgG or IgM) should be considered as positive for that particular antibody type (IgG or IgM). A pink-purplish procedural control band should always develop in the test device window to indicate that the test has been performed properly.

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