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#miseriathome
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Happy Slug Saturday from these guts from Fruits Basket!
Submission by @miseriathome
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vergess · 2 years
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hey remember when you did an experiment on those gamer supplement things and noticed how great they were for ADHD well i was doing research on antihistamines (reading wikipedia because i was too lazy to look up proper articles) and the thing you said adhd brains were deficient in idr the word starts with an a, antihistamines kind of uh also inhibit because it's connected to allergy responses sooooo just thought you should know about that
Acetylcholine.
While OTC allergy meds (1st and 2nd generation H1 agonists) do impact acetylcholine function, the most common ones are also the ones that have the least impact.
Basically, these meds can clog up the little parts of your brain that use acetylcholine to communicate with each other, so even though acetylcholine levels remain high, the function is reduced because it's not going in the little door for it.
Zyrtec (cetrizine), which is my daytime antihistamine is very low impact in this regard. Most of the non-drowsy allergy medications (that aren't relying on caffeine) have comparatively little impact. It's why they don't make you drowsy.
Benadryl (diphenhydramine) is IIRC the lowest impact of the drwosy ones, and is also my night time antihistamine.
Additionally, all of them (even the rarer ones) are very temporary in impact, with acetylcholine function returning to normal quickly when not being taken.
TBH, I'm far more concerned about the impact on antihistamines on people with mild seizure disorders than ADHD, all things considered.
Though, I would guess that the disproportionate "hangovers" that some people with ADHD (my GF for example) get from benadryl is related to this, now that you mention it.
Now, can you tell me more about this connection with acetylcholine and allergic responses? Because that's not something I've seen any information about, and I would definitely like to know more.
ETA: @miseriathome adds:
Benadryl is a first generation antihistamine, ie a (weak) anticholinergic with CNS and PNS effects. Second and third generation antihistamines are the ones that are non-anticholinergics and also do not act on the CNS as much.
In the above post, I generally used "non-drowsy" to refer to 2+ generaiton, and "drowsy" to refer to 1st generation. It's a good enough rule of thumb for walking around the pharmacy aisle. It is not a good rule of thumb if you're an actual pharmacist or medical professional or otherwise trying to be diligent about central nervous function at a level beyond "grocery store shopping."
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Oh yeah, so I made a second pilgrimage to the Big Band Barn this year to see the Marching 110 perform in exhibition at Bands of America Grand Nationals. It was actually my first time seeing a 110 field show outside of Homecoming and it was a blast seeing the band getting such an enthusiastic response from a crowd that’s more used to competition style. The band finished their performance by playing a combined number with United Sound, an organization that pairs student musicians and mentors of all abilities with the goal of providing inclusive music education experiences. It’s such an excellent musician and I was tearing up with pride from seeing the 110 participate in that. You can see photos on United Sound’s facebook here.
As for the competing bands, I was glad to watch a couple members of my corps perform, and one of our staff members was working with another band as well.
Photo credit for the first pic goes to @miseriathome, who, when asked to buy me a coke, decided to get the souvenir cup. I decided I am obligated to keep the Lucas Oil Stadium souvenir cup, plus, if they ever raise the price, then it was smart to get one now. It was also way too cold out. It was like 70 out on Thursday before we left, I almost packed shorts, and we woke on Saturday to find that it was snowing. Seeing the Summer Band Place be snowy is surreal.
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Your taste is exquisite. Even though we don't really share source material interests, your takes on things like queer bonding, power dynamics, and intimacy are *chef's kiss* Next Level Good Shit. I know "intricate rituals" is a meme, but at the same time it frequently feels like there really /aren't/ people who want to be fannish on that kind of level. I like living vicariously through your fannish analyses because the things you recognize in characters and their interactions are Gorgeous.
This is genuinely one of the best comments I've ever received recently, especially coming from you! Thank you so much!
I'm not sure what you mean by the "intricate rituals"/"being fannish on that level" bit - could you elaborate?
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intersex-ionality · 5 years
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miseriathome replied to your post “the dr who writes my t script is threatening to take me off of them...”
If you're in the US, here's an essentially crowdsourced map of all the informed consent clinics in the country which will let you have hrt without being assholes about it: https://www.reddit.com/r/asktransgender/comments/d6p05q/i_compiled_every_single_informed_consent_clinic/
Ah! Thank you so much!!
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aterabyte · 4 years
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How do I know you're not just as much of a bot as nostalgebraist-autoresponder?
:0
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olderthannetfic · 4 years
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Vine as fandom deletion
miseriathome replied to your post “A New History of Fandom Purges”
Wouldn't vine shutting down count by some of these metrics?
For sure!
Video is probably the worst hit of any medium: it always has fewer good platforms, they have been mass-purged more and entirely deleted more, remix of the actual material in a property is on shakier ground than completely original words and drawings based on a property, and individual fans are less likely to keep extensive backups because video content is large.
I’m more familiar with imeem, viddler, and blip.tv because the sorts of vidders I tend to know personally were on those. I’m sure vine had plenty of fannish video art, but I was barely aware of it as a platform when it was deleted.
To be honest, that list was made with an eye to having approximately one thing per year to visually demonstrate the depth of the problem. I’m sure I could find 10x that number of entries if I delved deeper.
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miseriathome replied to your post “Long time no see! I’m here for good now and I need everyone to read...”
Yes, I'd definitely give it a read
Thank you for your support ♥ i’m gonna start translating asap!
snailsarecute replied to your post  “Long time no see! I’m here for good now and I need everyone to read...”
                       I'd be super interested to read it! I'm all for more academic work into the behavior ticks that make up the genre, setting it apart as it's own thing. Just data in fandoms alone is interesting. Very cool!                    
Ohhh, this makes me so happy! I’m gonna start it asap so i can upload for you guys! I’m excited in share my work ahahaha I’ll post it here when I’m done!
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tenderwiki · 5 years
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popsicle moodboard for @miseriathome ❤
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vergess · 5 years
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Nick Wilde is positioned as a dad when Judy first meets him tho, and she buys the lie which means that Nick is a plausible daddy
Fuck!!! You’re so right!!! How could I forget the most basic factor imaginable??
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silver-and-ivory · 6 years
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What do you consider to be social consciousness and how do you feel it gets instilled in classrooms such that it shouldn't be (if that makes sense)?
(re: one of miseriathome’s posts that I responded to) (not sure if okay to link)
I don’t have a formal definition or anything, but what I inferred was that social consciousness was something like class consciousness? Like, “society is set up into these different classes of people and the *archy definitely exists and must be dismantled” is the sense I’m getting from the phrase.
I’m not averse to things like this being taught as things people believe or even as well-supported theories. I am averse to professors going to teach, idk, sociology courses or lit courses with the idea, “I’m going to instill in students a sense of revolutionary passion”.
I suppose that I’m less uncomfortable with “I’m going to teach students to recognize the oppressions extant in our culture”, but I am still not happy about professors teaching that.
Of course, things that are true ought to be taught no matter how Controversial they are. E.g. evolutionary biology professors probably do need to assume that evolution is true even if that’s a ~hot-button issue~.
And it’s true that “the political center” is arbitrarily defined and often biased in favor of the status quo or in favor of those in power.
And it’s also true that things like, say, white supremacy, are pretty clearly real things that need to be analyzed and that exist, and that analyses based on class are true in some respects and even occasionally useful.
But there’s something that really bothers me about the idea of professors wanting to sway students to their political side.
I think that the problem I had with your original phrasing was that the goal, in my opinion, of teaching things should not be to convince people to agree with a particular political perspective. It should be to expose them to a quality argument for the political perspective and then allow them to make their own decision.
(Disclaimer: I am not in college, I am not any kind of Academic Sociologist person, I am an amateur on the internet with an interest in Social Justice(TM) who had a few shitty ideologue high school social studies/lit teachers.)
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Unpopular opinion: cicadas are cuter in their nymph form than in their adult form
Didn't know this was a hot debate. I wasn't even sure what cicadas looked like (only what they sound like lmao) but having looked them up, I don't really think they're cute at all. I'm not a fan of the red eyes. I do prefer a fully grown bug though.
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barachiki · 4 years
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So we know Sherlock knits, but does he do amigurumi?
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These just keep happening.
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gostaks · 5 years
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@miseriathome replied to your post looking for recipes on the internet like no i do...
I’ve seen stand mixers at grocery stores but also best buy, so idk
hm, noted in case i ever get hijacked by stand-mixer-desiring brain parasites
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intersex-ionality · 5 years
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miseriathome replied to your post “This shit is why sociological education should be more fucking...”
I'm mad I had to discover the field of sociology for myself when I was already a teenager, YEARS AFTER we were already doing career aptitude tests in school to start thinking about our prospective life paths
It’s really fucked up. Like not only is it cordoning off a field of study that stands to benefit us all behind massive access barriers, but it’s also denying young people the tools to interrogate their societies, understand the failures and successes thereof, and work towards the betterment of themselves and their communities.
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aterabyte · 4 years
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6, 29, 53, 97 :D
6. pastel, boho, tomboy, preppy, goth, grunge, formal or sportswear?
Tomboy, goth, formal
29. best way to bond with you?
Cuddle, talk about fandoms we like, stay up late enough that I start talking about my feelings without overthinking it, have in-depth philosophical discussions, other stuff I'm probably forgetting
53. what is the current state of your hands?
Soft because I have Ehlers-Danlos
97. how many phone numbers do you have memorized?
3; my own and my parents'
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