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#dystrophia
call-me-camryn · 1 year
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An underrated Australian book set I just finished reading.
The books Hive and Rogue, by A.J. Betts tell the story of Hayley, a young beekeeper girl who finds a drip in the ceiling, which leads to her discovering mystery, and eventually the truth of her Dystopian world.
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I rate this one 5/5 personally!
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skinnyisclean · 8 months
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You know your body dystrophia is bad when you’ve lost over 10kg but still think you look the same
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microcosme11 · 10 months
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This is pretty brutal
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Did Napoleon Bonaparte suffer from hypopituitarism (dystrophia adiposo-genitalis) at the close of his life? by Leonard Guthrie (1913)
H/T @cafeguaba-blog for sending me the link to this article.
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littlewomenpodcast · 10 months
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Barbie Movie, Little Women and Fatphobia (Video Essay)
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Hello Little Women Fans
I turned the Little Women and Fatphobia episode into a video essay and talked a bit about Barbie too (and the skinny model). I hope you guys like this one. Do freel free to share it as the message is really important to us all!
Some of the criticism towards the 2019 Little Women, is the fact that a lot of the promotion of the film included several fatphobic comments from Gerwig regarding Friedrich's character. Obviously this is not ethical or morally correct. There is a problem within Little Women researh, because there are Alcott's scholars who dismiss Friedrich as a love interst for Jo because of fatphobia. Based on her diaries Louisa May Alcott seemed to have liked more stout and stacked men, and she even critices the looks of the skinny men who inspired Laurie's character. So the statements from Gerwig and these scholars are in contradict with Alcott herself. Another character in Little Women who is plus size is Meg, but in the films Meg has always been played by a conventionally skinny actress. In the last Little Women Book "Jo's Boys" Jo has actually gained some weight. Family quite cruely makes fun of it. Louisa May Alcott also suffered from body dystrophia. She became ill after her service in the Civil War and she was treated with mercury. The mercury treatment caused some major damage in her body and created mood swings, increased her weight and hightened up testosterone levels in her body making her look more masculine than she was and causing her constant pains. When her fans saw her they went away dissappointed because she wasn't pretty. In Little Women, there is an idea that love beautffies a person. Jo and Friedrich are beautified by their love, in each others eyes.
Feel free to share the video as the message is quite important :D and thanks to all of you who have recently subscribed to the Little Women podcast!
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Hey, I was wondering what your take on Scarecrow with a trans man s/o would be like? I love your posts :3
Thank you!
Scarecrow x Trans Man S/O
If they meet before transition he would give him all the support
He needs hormones? Don't worry Jon will steal them for him
Lands him some of his clothes if he wants to change style
Talks with S/O about his feelings and helps him with dystrophia
Helps choose new name
If meeting is after transition he would ask him stuff like: how long he'd know, does he has scars
Would love to run over top scars with his fingers, thinks they're beautiful
It doesn't really matter to him as long as he loves him
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dmgh85 · 6 months
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Median nail dystrophy—also known as dystrophia unguium mediana canaliformis, nevus striatus unguis, or median canaliform dystrophy of Heller.
Its a benign condition that resolved sponaniously and recurrent.
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human-antithesis · 7 months
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Scid
Splytz canals curdling Shoving the matriz flapless Span gurgling in excrement Stimulates to execrates Blastome incubates slaughtering Seeing your paradise croup Dermal connective focal tissues A pitfall in purulent swells Spitting as I still secreting scid Pathofysiologic changes blistering In a denuded basalhacked crisp Tangles burst less Endoparasites in Placentic fibras wounded Upon my degrading dystrophia Dismutase acuta Transgenic dissect Consumates beyond the spleen Septic osseous eroded remains As I obtain the cultures Of the feces And bile fluyds Over the vacuoles cortex Surgycal irritating Despite suction Engorging the full drainage Consumes dementia blobs With sprue destruction As I devast in you ecceme Necrotical develops Oxidase scalpels Macabre pathogenicity Epizootic abrupts Malleus chronic form Sub acute undulant Extremely rotted Syal smashed Of granulomatous reaction Shredded beyond comprehension Squilling febrille pain Phagoticised in the liver Croacted being spilled in the uvea Disgusting to grow Serologyc the iliac crest Followed by psoriac fractures Inhibing frolic down My pleasures Unusual gromes on the trauma Cervycal fractures and rapture Bladder abscess Skin abbrassion Nephrectomy tract infection Cutting the shaped Eated proteous Post operative half raped Enteral ripped Septicum changes colemic illness Asphyxiating venipunctured mess Masticated in excrement Scid fucked underlying awaits One half minced Seeding leeds friyng suppurative Large colonies of vacuoles My desires in perverse lust Putrida ecstasia!! Dementia flows In the matrix drainage Lacking the mucing clots Swelling soft As I still devast
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feiyuebio-lottieshi · 2 years
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Mouse Myotonin-Protein Kinase (DMPK) ELISA Kit
Myotonin-Protein Kinase (DMPK) Introduction
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Myotonin-protein kinase (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase (DMPK) is an enzyme that in humans is encoded by the DMPK gene. The dmpk gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and Rho kinase family. Data obtained by using antibodies that detect specific isoforms of DMPK indicate that the most abundant isoform of DMPK is an 80-kDa protein expressed almost exclusively in smooth, skeletal, and cardiac muscles.[9] This kinase exists both as a membrane-associated and as a soluble form in human left ventricular samples. The different C termini of DMPK that arise from alternative splicing determine its localization to the endoplasmic reticulum, mitochondria, or cytosol in transfected COS-1 cells. Among the substrates for DMPK proposed by in vitro studies are phospholemman, the dihydropyridine receptor, and the myosin phosphatase targeting subunit. However, an in vivo demonstration of the phosphorylation of these substrates by DMPK remains to be established, and a link between these substrates and the clinical manifestations of myotonic dystrophy (DM) is unclear. Myotonin-protein kinase is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. Although the specific function of this protein is unknown, it appears to play an important role in muscle, heart, and brain cells. This protein may be involved in communication within cells. It also appears to regulate the production and function of important structures inside muscle cells by interacting with other proteins. For example, myotonic dystrophy protein kinase has been shown to turn off (inhibit) part of a muscle protein called myosin phosphatase. Myosin phosphatase is an enzyme that plays a role in muscle tensing (contraction) and relaxation.
Mouse Myotonin-Protein Kinase (DMPK) ELISA Kit Test method
This kit uses sandwich ELISA to detect the concentration of  Myotonin-Protein Kinase (DMPK) The microtiter plate provided in this kit has been pre-coated with an antibody specific to Myotonin-Protein Kinase (DMPK). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Myotonin-Protein Kinase (DMPK). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain of DMPK, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Myotonin-Protein Kinase (DMPK) in the samples is then determined by comparing the OD of the samples to the standard curve.
www.feiyuebio.com
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phrynewrites · 2 years
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as a trans person i really respect your response to me! i appreciate the thought you are putting into this. while i would love to see you write about them comforting each other with their dysphoria and tackling trans topics, i appreciate that you aren't going to write these things until you do research. as a trans fan if you ever want to ask questions i'm happy to pop into dms!
Thank you! That kind of puts me at a bit of ease tbh, like I’m not getting everything totally wrong lol
Also I really appreciate it and will be sure to ask when I have questions!
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tendous-socks · 3 years
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TOKYO REVENGERS HEADCANONS OF ME BEING NON BINARY / REACTING TO SOMEONE BEING NON BINARY
tw: ⚠️⚠️kisaki⚠️⚠️ and manga spoilers, mentions of death, transphobia,
would misgender and dead-name me
1.kisaki.
must i need an explanation?😐
2. shion
“ what’re you gonna do about it?? HUH?? WHAT’RE YOU GONNA DO ABOUT IT ???”
actively looks for a fight
… if y’all are in a relationship he’d still call you his “girl” but beats people up for doing so….
3. mucho
i get the vibes that he’s traditional
would silently stare in judgment
4. mochi
he just doesn’t care clslfkxkslk
thinks it’s weird
“ nor/mal”
7. rindou..
“you either have a pen or a vag. “
8.ran
“interesting”
*continues dead naming me*
9. KOKO
he would be nicer about it when he’s in toman due to inui… but once they’re separated- an ABSOLUTE MEANCE
… reluctantly apart of the protection squad with inui ( enjoys beating people up tho)
10. bontent mikey
… he’s just so tired and doesn’t really care ) that is if you’re not close with him… but then again how close can you really get?)
11. ) PAH CHIN
AND ONLY BECAUSE HE WAS IGNORANT AND HIS FATHER DIDN BELIEVE IN THAT STUFF AND HE DIDNT KNOW BUT THEN ( if y’all are close ) HE’D FEEL BAD AND AFTER YOU EXPLAINED IT TO HIM HE TOLD PEH CHIN TOO AND WERE SURPRISINGLY SUPPORTIVE
but if y’all ain’t close he would slowly get the hint… this is canon.
because i said so-
11. sanzu…
he’s quietly judging you
EDIT
SOMEONE SAID SANZU WOULD USE ANY PRONOUNS AND I REALLY LIKE THAT HC-
SO SANZU WOULD PROBABLY JUST ‘ SILENTLY JUDGE YOU’ SO OTHERS DONT CATCH ON MHMHM
12. akashi
traditional- plus it was a different era for him growing up so…
(would glare at someone if he really did see you getting emotionally distressed)
13. smiley
“ that’s one of the most stupidest shit ive ever fucking heard 😁”
.🙁
“ you either have tits or a dick “
.☹️
but would beat people up if you get SUPER upset ( call it his protect instincts with angry, but would send people to the hospital)
14. taiju
“ i wanna church girl who goes to church and reads her bible “
would spit at me
- WHO WOULD BEAT SOMEONE UP FOR DEAD-NAMING / MISGENDERING
1. PAH CHIN AND PEH YAN
THEYRE ABSOLUTE MENACES TO SOCIETY IF SOMEONE CALLS YOU A GIRL / BOY
head canon : during tenjiku you were there and had to adjust your transtape cause it was coming lose 🙄
which is literally the most annoying thing in the world-
and shion saw you.
he came up and was like “ HUH WHAT’VE WE GOT HERE?? A GIRL PRETENDING TO BE A G-“
couldn’t even finish his sentence with how fast peh chin clocked his ass 🤭
( peh yan supremacy)
2. my main man takemichy
no explanation needed ( maybe deadnamed you only once cause he didn’t know)
3. inui cause i said so
5. BAJI BAJI
BAJI WOULD ALMOST KILL A DUDE FOR CALLING YOU YOUR DEAD NAME
i KNOW mama baji raised him right ✋🙄
almost clocked chifuyu when you told him about your first encounter kcksldofospdoco
almost clocked your mom when she said “you got it girlfriend”
she was confused when she saw you desperately trying to prevent the next criminal minds episode
best listener for body dystrophia fight me 🙉❤️
6. senju
*comes out*
“..oh okay! anyways as i was saying [preferred name] “
would need some gentle reminders only once or twice cause i will say it does take a bit of time for people to get used to it and there are always a few slip ups
tells akashi about your pronouns ( ONLY WITH YOUR CONSENT OFC)
( promises to try and be more girly if he calls you by them and your preferred name)
she wants you to go into more details about what you’re feeling cause she’s genuinely very interested about everything and she wants to know more about you.
7. emma 😻 vv supportive 🙌🙌
*sicks mikey and draken out on anyone who hurts your feelings
“you know [blah blah blah] from history?”
“of course yeah “
“yeah he ended up calling me slur during class- what’re you doing?”
*emma pulling out her phone
“hm? oh nothing don’t worry about it”
gave more insight about it to draken and mikey
8. HINA
YALL SAW HOW SHE SLAPPED MIKEY-
THIS GIRL WOULD D R A G A BITCH BY THEIR HAIR IF SHE SAW THEM BULLYING YOU
the one of correct takemichy
9. yuzuha
hina but 10x worse
trips transphobes for shit and giggles 🤪🤞
i like to think that the girls (all 4) would just all stare down a girl who was shit talking you and just pick her apart mercilessly ( a little ooc but this is my head canons so they can be whatever i say they are)
ones idk about
1. mikey
he knows that you can handle yourself so he lets you correct people.
or
sometimes he’ll jump in and correct them instead for one of two reasons.
1. he felt like it
2. they kept calling you your dead name and misgendering you EVEN THOUGH you already corrected them
but if the person ACTIVELY does that and says some… not so fruity things. he’ll send em to the hospital and end up on life support 😌☝️
like dom tertto, he cares about his family. and toman is his family, and you’re in toman ( not THAT kind of y/n way 🙄 )
“ BE WHO YOU AREE🌈🌈🌈🌈🤪🤞🏳️‍🌈🏳️‍🌈🏳️‍🌈”
1. draken
… listen… idk why, but i just don’t SEE him beating people up for misgendering me… well okay i kinda see it,
but he’d be like, “ i don’t understand what you’re going through, but i support you and if you want to talk about it i’m here”
wants to try and understand so like i said before, he lets you rant about what you’re feeling
would let you handle your own battles cause your strong enough to
a true king 😎🙌
does in fact throw punches when it gets REALLY BAD
2. angry
… idk h o w empathic he is and how mad he’d have to be on your behalf when people actively kept misgendering you to become the blue ogre.
but he’d just start crying at the confrontation.. 😐
my hero ig 🤥
3. izana
“ that’s fucking stupid”
*beats up middle aged woman who said for you to “ have a good day ma’am”
but if y’all close he’ll only say it’s stupid once when he sees you genuinely upset and ignoring him
“ be who you are.. 🌈”
4. kaku
same boat as izana, A LOT less judgmental
5. mitsuya
won’t hesitate to send a bitch flying
actively corrects people
( teaches luna and mana about your pronouns for the next time you come over 🕺🏻)
TAKES YOU SHOPPING FOR CLOTHES
6. haitani brothers
*actively bullies you
*bullies kid into the grave for looking at your chest area
7. …hakkai
he accidentally slipped up once🤒
WHEN I SAY THIS MANS FACE WENT PALE- HE DIDNT TALK TO YOU FOR A W E E K MINIUM CAUSE HE FELT SO BAD
YOU KEPT TELLING HIM THAT ITS FINE-
BUT HE FELT AWFUL
( has nightmares about it)
8. chifuyu would only do it in his mohawk era cause he wanted to seem metal and impress da boys 🥶🥶☝️☝️
pulled you aside at the end of the day to apologize
( like i said before, baji almost clocked him when you told him about your first encounter )
who am i kidding they’re all in gangs, they’d probably kill someone if they hurt you cospwpfoslief
——————
IF YALL GOT ANYMORE IDEAS LMK CAUSE IM INVESTED IN YHIS AND WANNA HEAR WHAT YALL THINK
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teachingrounds · 3 years
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Klippel-Feil Syndrome aka congenital dystrophia brevicollis aka cervical vertebral fusion syndrome is when 2 or more bones in the neck fuse together during development, leading to a short and broad neck with limited movement. Unlike Klippel-Trénaunay(-Weber) Syndrome, KFS does NOT involve hyperplasia. Most commonly associated with mutations in the GDF6, GDF3, and MEOX1 genes. C2-C3 fusion is often autosominal dominant in inheritance, while C5-C6 fusion is often autosomal recessive. Life expectancy in <50 years due to associated heart defects. Treatment is therapy and surgery for the anatomical abnormalities. First described in 1885 by Maurice Klippel and Andre Feil.
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grelleswife · 3 years
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Do you think if sebas is genderfluid as you guys say, he somehow sometimes hates being male?? or feels uncomfortable?? I just really wonder how dystrophia would be like for a character not human in the first place??. 🤔
Hi, anon! I think it would largely depend on Sebastian's circumstances. In hell, if the shape they wore no longer suited the gender identity (or absence of gender) with which they identified at a given moment, the demon could simply change form as they saw fit. Problem solved! The real difficulties might arise during a contract on Earth, especially if Sebastian's master insisted he maintain a single, consistent appearance. I imagine that young Sebas struggled to understand what human concepts of "gender" and the binary even meant at first. And depending on how long the contract lasted, it's entirely possible that the demon would experience frustration and dysphoria from not being able to adjust their body to best reflect their inner self. However, they might view that pain as one of the temporary sacrifices they had to make in order to reap the benefits of their master's soul farther down the road. But the demon is probably relieved that he isn't trapped in a physical body 24/7 like we mortals are!
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km1388 · 2 years
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I’ve learned with body dystrophia that the worst is usually my bedroom sometimes the bathroom mirror and the best is the tv reflection when standing
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littlewomenpodcast · 1 year
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Greta Gerwig's Fatphobic Comments On Little Women
Now in AOO
Some of the criticism towards the 2019 Little Women, is the fact that a lot of the promotion of the film included several fatphobic comments from Gerwig regarding Friedrich's character. Obviously this is not ethical or morally correct. There is a problem within Little Women researh, because there are Alcott's scholars who dismiss Friedrich as a love interst for Jo because of fatphobia. Based on her diaries Louisa May Alcott seemed to have liked more stout and stacked men, and she even critices the looks of the skinny men who inspired Laurie's character. So the statements from Gerwig and these scholars are in contradict with Alcott herself.
Louisa May Alcott also suffered from body dystrophia. She became ill after her service in the Civil War and she was treated with mercury. The mercury treatment caused some major damage in her body and created mood swings, increased her weight and hightened up testosterone levels in her body making her look more masculine than she was and causing her constant pains. When her fans saw her they went away dissappointed because she wasn't pretty. In Little Women, there is an idea that love beautffies a person. Jo and Friedrich are beautified by their love, in each others eyes.
youtube
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aledethanlast · 7 years
Conversation
Me: I am a boy. This is a fact.
My brain, every now and again, for no discernible reason or prompting: Oh is it now?
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otisandmaeve · 4 years
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i watched a youtube video of an interview with aimee lee wood, the actress who plays aimee, and she talked about filming the opening scene of sex ed topless whilst dealing with body dystrophia disorder. the fact that she boldly and bravely did that in spite of fear, anxiety, and presumably 100 other negative emotions is so amazing. she did it because she knew impressionable girls would be watching the show and seeing themselves in her character, engaging in sexual activity and not being shamed and not having “perfect” bodies. she said she wanted to tell the story as honestly and well as she could, and the environment was really safe during those scenes. her strength makes me feel as if i can carry through my struggles with ED recovery, and if you guys are dealing with any of these issues, i hope you feel seen and that aimee’s bravery will help you as well. if you’re not, which is FANTASTIC, i hope u learned something really neat because i had no idea. maybe i’m just late LOL
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