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organtransplantpune1 · 2 months

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What Cause Liver Failure

The liver is one of the most important organs working around the clock to keep you healthy and alive. It performs more than 500 tasks, including detoxification, protein synthesis and the production of bile that helps in the digestion of fats. Yet, several factors, including health problems, can cause serious liver diseases and lead to liver failure, a life-threatening condition that warrants immediate medical attention.

With is current generation and world-magnificence facilities, NewLife Gastro Liver Clinic , is famous for providing the best treatment for all degrees of liver sicknesses. If you’re involved approximately your liver health, examine on as our doctors list the overall signs of common liver diseases and the way extraordinary situations can purpose liver failure.

Signs and Symptoms of liver disease

While liver ailment doesn’t constantly reason great signs, the subsequent symptoms and symptoms may also imply a few sort of liver issue. Also, signs may also range depending on the underlying reason.

Jaundice (yellow pores and skin and eyes)

Dark urine

Nausea

Vomiting

Chronic fatigue

Itchy pores and skin

Easy bruising

Swollen legs

Seek hospital therapy when you have any of those signs or chronic symptoms and symptoms that fear you.

Causes of liver failure

The reason of liver failure relies upon at the type of liver failure – acute or persistent. Acute liver failure happens rapidly (in days or weeks), while persistent liver failure develops regularly over time.

Acute liver failure may be as a result of many extraordinary things, even though the precise purpose can be unknown in a few cases. Possible reasons are:

. Viral infections – like hepatitis A, B or E

. Reactions to prescription medicinal drugs together with antibiotics, antidepressants, anti-seizure medicinal drugs

. Reactions to few natural medicinal drugs and supplements

. Overuse of positive capsules like acetaminophen (Tylenol)

. Autoimmune situations like autoimmune hepatitis

. Metabolic problems together with Wilson’s disease

Chronic liver failure regularly outcomes from cirrhosis (intense scarring of the liver), making it difficult or not possible on your liver to function. Cirrhosis is because of many types of liver sicknesses and situations together with alcohol-associated liver sicknesses, non-alcoholic fatty liver disease (NAFLD), persistent hepatitis B or C infection, sicknesses that have an effect on your bile ducts like biliary stricture, biliary atresia etc.

Generally, liver failure takes place after cirrhosis, which frequently has no symptoms and symptoms or signs and symptoms at some stage in preliminary section and the liver is just too broken to preserve working. So, it’s a slow method in maximum cases.

Treatment and prevention of liver failure

The main purpose of treatment is to cope with the basic purpose of liver damage Treatment alternatives for liver failure are medication, supportive care, and liver transplant. In human beings with cirrhosis or give up degree liver disease, a liver transplant is frequently required. Lifestyle adjustments are frequently endorsed as a part of remedy.

You can reduce your risk of liver failure with the aid of using taking easy steps such as:

. Eating a wholesome food regimen wealthy in culmination and greens at the same time as reducing lower back on fatty foods.

. Maintaining a wholesome weight.

. Avoiding alcohol consumption.

. Getting vaccinated towards hepatitis A and B.

. Following guidelines whilst the usage of medications.

. Practicing appropriate private hygiene.

. Having ordinary physical examinations together along with your doctor.

Dr. Ninad Deshmukh is one of the best Liver transplant surgeon in pune India. He has performed more than 100 liver transplant surgeries as a Chief Surgeon. Currently, he is available at Deenanath Mangeshkar Hospital Pune. He is an expert in all types of liver transplants and is the preferred choice for domestic as well as international patients. NewLife Gastro Liver Clinic is one of the best liver transplantation clinics in India. If you have any liver-related problems, Dr. Ninad Deshmukh is the best doctor for you.

Book your Appointment Now!

#bestliverspecialistinpune #hepatologistinpune #hepatologistdoctorinpune #livingdonorlivertransplantinpune #livertransplantinpune

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virinchihospitals90 · 8 months

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Liver Transplant surgery in Hyderabad - Virinchi Hospital

A liver transplant is a life-saving procedure where a malfunctioning liver is substituted with a healthy one. The liver, an indispensable organ, is responsible for numerous vital roles, including the metabolism of drugs and toxins, as well as protein synthesis. Any disturbances in liver functions can lead to significant health complications. For individuals with end-stage liver disease, liver transplant surgery in Hyderabad offers a promising solution for prolonged survival.

Hyderabad boasts several specialized surgeons and best liver transplant surgeons who are well-equipped and experienced in executing liver transplants. Not only do these experts provide remarkable outcomes, but they also maintain a commendable liver transplant success rate. Moreover, the liver transplant cost in Hyderabad is more economical compared to many other regions.

So, who is the right candidate for a liver transplant?

The primary candidates for a liver transplant are those whose livers are no longer functioning optimally. This can be due to:

Acute Liver Failure: This is a condition where a previously healthy liver suffers from extensive damage in a short period. Causes might include acetaminophen overdose, adverse drug reactions, or specific viral infections.

Chronic Liver Failure: Continuous damage and repair over an extended period can lead to irreversible liver scarring, known as cirrhosis. While some medications might alleviate the symptoms, a liver transplant is often the definitive solution.

Furthermore, other prevalent reasons for undergoing liver transplant surgery in Hyderabad encompass individuals diagnosed with liver cancer, benign liver tumors, or those grappling with inherited liver diseases.

If you're on the lookout for the best liver transplant hospital or the best liver transplant surgeon in Hyderabad, it's worth mentioning that Virinchi hospitals stand among the premier medical institutions, boasting esteemed professionals in this specialized domain.

Address: Virinchi Circle, Rd Number 1, Banjara Hills, Hyderabad, Telangana

Phone.no: 040 46999999

Website: https://virinchihospitals.com/transplant/liver-transplant/

#Best liver transplant hospital #Best liver transplant surgeon in Hyderabad

#Liver Transplant surgery in Hyderabad #liver transplant

#Best liver transplant hospital #Best liver transplant surgeon in Hyderabad #Liver Transplant surgery in Hyderabad #liver transplant

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drdhavalmangukiya · 8 months

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How to Keep your Liver Healthy: Know It All from a Liver Specialist in Surat

Maintaining a healthy liver is crucial for overall well-being and longevity. As the largest internal organ, the liver plays a vital role in detoxification, metabolism, and digestion. However, due to our modern lifestyles and various factors, liver diseases are on the rise. To shed light on this issue and provide expert insights, Dr. Dhaval Mangukiya, one of the Best liver surgeon in Surat has given a comprehensive guide in this blog , where we’ll explore the importance of liver health, common liver diseases, and practical tips shared by the expert, enabling you to take charge of your liver health.

Understanding Liver Health:

Before delving into the ways to maintain a healthy liver, it’s essential to understand its functions. Often referred to as a biochemical factory, the liver performs over 500 essential functions in the body. The liver aids in the detoxification process by filtering toxins from the blood, produces bile to aid digestion, metabolizes nutrients, stores vitamins, involved in the production of clotting factors, and synthesis of cholesterol, among many other important processes. Its multifunctional nature highlights the significance of maintaining a healthy liver. However, poor diet, excessive alcohol consumption, sedentary lifestyles, viral infections, and certain medications can all contribute to liver damage.

Preventing Liver Diseases:

To prevent liver diseases, it’s crucial to adopt a proactive approach towards liver health. The best liver surgeons in Surat share a consensus on these key measures:

Balanced Diet: Emphasize a diet rich in fruits, vegetables, whole grains, and lean proteins while minimizing processed foods, saturated fats, and sugary beverages.

Limit Alcohol Consumption: Excessive alcohol intake can lead to liver damage. Men should limit themselves to two drinks per day, while women should consume no more than one.

Vaccinations: Protect yourself from hepatitis A and B by getting vaccinated. These viral infections can cause severe liver damage if left untreated.

Regular Exercise: Engage in moderate physical activity regularly to maintain a healthy weight and reduce the risk of fatty liver disease.

Medications and Supplements: Consult your liver specialist before taking any medications or supplements, as some can cause liver damage.

Expert Insights and Recommendations:

Some of the best liver doctors in Surat recommend regular check-ups to monitor liver health and detect any potential issues early on. If needed, reach out to us at SIDS Multispeciality Hospital, which is known for the best liver surgery in Surat, for a general check-up.

Apart from these, other additional measures you can follow are:

Stay Hydrated: Drinking an adequate amount of water helps flush out toxins and keeps the liver functioning optimally.

Limit Medication Overuse: Excessive use of over-the-counter pain relievers like acetaminophen can harm the liver. Follow recommended dosages and consult a healthcare professional if you have concerns.

Avoid Smoking: Smoking increases the risk of liver cancer. Quitting or reducing smoking significantly improves liver health.

Maintain a Healthy Weight: Obesity and excess body fat increase the risk of fatty liver disease. Adopt a healthy lifestyle, including a balanced diet and regular exercise, to maintain an ideal weight.

Practice Safe Sex: Unprotected sex can lead to hepatitis B and C infections, which can cause chronic liver diseases. Use protection and get tested regularly.

Fun Fact: Did you know that the liver serves as a blood reservoir, holding a substantial amount of blood within its vascular system? In fact, about 13% of the body’s total blood volume is stored in the liver. This allows the liver to respond quickly to changes in blood volume and supply blood to other parts of the body as needed.

Conclusion:

Liver diseases often exhibit few or no symptoms in the early stages, earning the liver the reputation of being a “silent organ.” Conditions such as fatty liver disease, hepatitis, and cirrhosis may progress silently for years before noticeable symptoms emerge. Regular liver check-ups and screenings are crucial for early detection and effective management.

A healthy liver is vital for overall well-being, and taking care of it should be a top priority. By incorporating these expert recommendations from a liver specialist in Surat, you can reduce the risk of liver diseases and promote liver health. Remember to adopt a balanced diet, limit alcohol consumption, exercise regularly, and avoid smoking. Additionally, stay hydrated, be cautious with medications, maintain a healthy weight, and practice safe sex. Regular check-ups with a liver specialist will ensure early detection of any liver-related issues. Prioritize your liver health and reap the benefits of a vibrant and energetic life.

#drdhavalmangukiya #liver specialist #surat

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drninad · 9 months

Text

What Cause Liver Failure

Signs and Symptoms of liver disease

Jaundice (yellow pores and skin and eyes)

Dark urine

Nausea

Vomiting

Chronic fatigue

Itchy pores and skin

Easy bruising

Swollen legs

Seek hospital therapy when you have any of those signs or chronic symptoms and symptoms that fear you.

Causes of liver failureThe reason of liver failure relies upon at the type of liver failure – acute or persistent. Acute liver failure happens rapidly (in days or weeks), while persistent liver failure develops regularly over time.

Acute liver failure may be as a result of many extraordinary things, even though the precise purpose can be unknown in a few cases. Possible reasons are:

. Viral infections – like hepatitis A, B or E

. Reactions to prescription medicinal drugs together with antibiotics, antidepressants, anti-seizure medicinal drugs

. Reactions to few natural medicinal drugs and supplements

. Overuse of positive capsules like acetaminophen (Tylenol)

. Autoimmune situations like autoimmune hepatitis

. Metabolic problems together with Wilson’s disease

Treatment and prevention of liver failure

You can reduce your risk of liver failure with the aid of using taking easy steps such as:

. Eating a wholesome food regimen wealthy in culmination and greens at the same time as reducing lower back on fatty foods.

. Maintaining a wholesome weight.

. Avoiding alcohol consumption.

. Getting vaccinated towards hepatitis A and B.

. Following guidelines whilst the usage of medications.

. Practicing appropriate private hygiene.

. Having ordinary physical examinations together along with your doctor.

Dr. Ninad Deshmukh is one of the best Liver transplant surgeon in pune India. He has performed more than 100 liver transplant surgeries as a Chief Surgeon. Currently, he is available at Deenanath Mangeshkar Hospital pune. He is an expert in all types of liver transplants and is the preferred choice for domestic as well as international patients. NewLife Gastro Liver Clinic is one of the best liver transplantation clinics in India. If you have any liver related problems ,Dr Ninad Deshmukh is the best doctor for you. Book your Appointment Now!

#bestLivertransplantsurgeoninpune

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boysareloose · 10 months

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Vitamin Water for Hangover

If you have ever been drunk in your life, then you have probably also experienced a hangover. Whether a really bad one or just a mild one, a hangover is never pleasant and it comes with a number of extremely annoying symptoms which no person in the world wants to experience. For over-the-counter aches, our Plantwater can help when you endure headaches or nausea. However, avoid acetaminophen, which may cause liver harm when combined with alcohol. In addition, vitamin C plays a necessary position in maintaining our glutathione levels - nutrient water.

Vitamins Plant base water are the micronutrients that help our body with its numerous chemical processes which occur on a daily basis, from protein synthesis to neural connections and they are crucial to pretty much everything that happens in our body. For this reason, no matter which process you want to expedite or improve, there is a vitamin that can help you - vitamin water.

While the best way to handle hangovers is to not experience them in the first place, if you do have them, there are things you can do to feel better. For example, some people claim that you can take minerals and vitamins to help with hangovers. Vitamins and minerals are available in many supplements and in a number of beverages. Where to find vitamin B you can take different vitamin B 12 on their own or combined with other B vitamins.

According to some people, a good way to prevent hangovers is by consuming drinks with minerals and electrolytes before they start drinking alcohol or while they’re drinking it. In this view, drinks with vitamin help restore vitamins, minerals, and water to counteract the dehydrating effects of alcohol. For more information, please visit our site https://www.plantwater.com.au/

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juniperpublishersmaterialscience · 10 months

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Liquid Chromatography-Mass Spectrometry Based Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated L-Cysteine

Authored by: Snehasis Jana

Abstract

L-cysteine is a semi-essential sulfur-containing amino acid found in nails, skin, hair, etc. in the body. This study was performed to investigate the impact of the Trivedi Effect® on the structural properties and the isotopic abundance ratio of L-cysteine using LC-MS analytical techniques. L-cysteine sample was divided into control and treated parts. The treated part only received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Dahryn Trivedi. The LC-MS spectra of both the control and treated samples at retention time (Rt) 1.96 minutes exhibited the mass of the molecular ion peak adduct with hydrogen ion at 122 along with low molecular fragmented mass peaks at m/z 105, 102, 87, 76, and 59 for C3H5O2S+, C3H2O2S•+, C3H5NO22+ or C3H5NS•+, C2H6NO2+, and C2H3O2+, respectively were also observed. The peak area of the treated sample (1960679.58) was significantly increased by 8.02% compared to the control sample (1815060.18). The isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O or 33S/32S) and PM+2/PM (34S/32S) in the treated L-cysteine was significantly increased by 41.86% and 32.39%, respectively compared with the control sample. Hence, the 13C, 2H, 15N, 17O, 33S, and 34S contributions from C3H8NO2S+ to m/z 123 and 124 in the treated L-cysteine were significantly increased compared to the control sample. The changes in peak area and isotopic abundance ratios might be the cause of changes in nuclei, possibly through the interference of neutrino particles via the Trivedi Effect®-Consciousness Energy Healing Treatment. The increased isotopic abundance ratio of the treated L-cysteine may increase the intra-atomic bond strength, increase its stability, and shelf-life. The novel Biofield Energy Treated L-cysteine might have increased the stability, solubility, bioavailability, and shelf-life compared to the control sample. The new form of treated L-cysteine would be a better and more stable precursor in the food, cosmetics, pharmaceuticals, personal-care products, additives to cigarettes (act as an expectorant), preventative or antidote for some of the negative effects of alcohol, acetaminophen overdose, clinically used ranging from baldness to psoriasis, excellent for the treatment of asthmatics by enabling them to stop theophylline and other medications, enhances the effect of topically applied silver, tin and zinc salts for preventing dental cavities. In the near future, this Biofield Energy Treated L-cysteine may play a better role in the treatment of diabetes, psychosis, cancer, and seizures.

Keywords: Biofield Energy; Consciousness Energy Healing Treatment; L-cysteine; The Trivedi Effect®; LC-MS

Introduction

Cysteine is a semi-essential sulfur-containing amino acid found in nails, skin, hair, etc. in the body. It contains a thiol group and available as a chiral molecule with dextrorotation (D) and levorotation (L) forms [1]. Cysteine is a non-essential amino acid but may be essential for new-borns, the elderly, and individuals with specific metabolic disease or malabsorption syndromes. The cysteine plenty available in egg, meat, milk, garlic, onions, red peppers, oats, broccoli, wheat germ, brussels sprout, sprouted lentils, etc. Industrially it is also prepared from animal feathers, hair, and even from chemical synthesis [1-3].

Due to its high reactivity of the sulfhydryl group of cysteine (nucleophilic in nature) has numerous biological functions, i.e., it acts, as a precursor to the antioxidant glutathione and iron-sulfur clusters, metal cofactors in enzymes, detoxification, metabolic functions, protein synthesis, collagen production, translation of messenger RNA molecules to produce polypeptides, etc. [1-6]. It is also a precursor in the food, cosmetics, pharmaceuticals, personal-care industries, additives to cigarettes (as an expectorant), preventative or antidote for some of the harmful effects of alcohol (i.e., liver damage and hangover), acetaminophen overdose, production of more wool from sheep, clinically used ranging from baldness to psoriasis, used for the treatment of asthma, enhances the effect of topically applied silver, tin and zinc salts for preventing dental cavities [1,6-9]. Many research work claiming that, in the near future, cysteine may play an important role in the treatment of diabetes, psychosis, cancer, and seizures [10]. The stability of L-cysteine is an issue in the neutral or slightly alkaline aqueous solutions, which is oxidized to cystine by air, and on decomposition, it emits very toxic fumes of sulphur oxides and nitrogen oxides [6].

The physicochemical properties of L-cysteine pay a very important role in the food, cosmetic, pharmaceutical, nutraceutical, and other industries. The Trivedi Effect®- Consciousness Energy Healing Treatment has the astonishing abilities to transform the characteristic properties of both living and non-living object(s) [11-15]. The Trivedi Effect® is a natural and only scientifically proven phenomenon in which an expert can harness this inherently intelligent energy from the “Universal Energy Field” and transmit it anywhere on the planet via the possible mediation of neutrinos [16]. An energy field generated around the body due to the continuous movement of the charged particles in the body known as “Biofield”. The object(s) received the “Energy Therapy” respond to a useful way is known as the Biofield Energy Healing Treatment. There are several Biofield based Energy Therapies that are used nowadays against various disease conditions [17-19]. Biofield Energy Healing therapy has been recognized worldwide as a Complementary and Alternative Medicine (CAM) health care approach by the National Center of Complementary and Integrative Health (NCCIH) with other therapies, medicines and practices such as Ayurvedic medicine, yoga, meditation, homeopathy, traditional Chinese herbs and medicines, naturopathy, chiropractic/osteopathic manipulation, Qi Gong, Tai Chi, aromatherapy, acupressure, acupuncture, healing touch, hypnotherapy, Reiki, cranial-sacral therapy, etc. [20]. These CAM therapies have been adopted by most of the U.S.A. population with several advantages [21]. Similarly, the Trivedi Effect®- Consciousness Energy Healing Treatment also been reported with significant impact on the properties of polymers, ceramics, metals, organic compounds, cancer cell line, microbes, improved skin health, bone health, improved agricultural crop yield, productivity, and quality, and altered the isotopic abundance ratio, improved bioavailability of pharmaceutical/ nutraceutical compounds [22- 37].

The analysis of the natural stable isotope has the importance of many applications to understand the isotope effects resulting from the alterations of the isotopic composition [38-40]. Gas chromatography–mass spectrometry (GC-MS) and liquid chromatography–mass spectrometry (LC-MS) analytical techniques are the widely used analytical techniques for the analysis of isotope ratio with sufficient precision [39]. The Trivedi Effect®-Consciousness Energy Healing Treatment could be an economical approach to alter the isotopic abundance of L-cysteine with improved physicochemical properties for the food, cosmetic, pharmaceutical/ nutraceutical, and other industries. Thus, this study was designed and evaluated the LC-MS based structural characterization and the isotopic abundance ratios in the Trivedi Effect® - Consciousness Energy Healing Treated L-cysteine compared to the control sample.

Materials and Methods

Chemicals and Reagents

The test sample L-cysteine (>98%, titration method) was purchased from Alfa Aesar, India. Other chemicals like methanol, acetonitrile, and ammonium acetate were purchased from Merck, India.

Consciousness Energy Healing Treatment Strategies

The test sample L-cysteine powder was divided into two parts. One part of the L-cysteine powder sample did not receive the Biofield Energy Treatment called the control sample. However, the other part of L-cysteine was received the Trivedi Effect®- Consciousness Energy Healing Treatment remotely under standard laboratory conditions for 3 minutes by the renowned Biofield Energy Healer, Dahryn Trivedi, USA, known as the Biofield Energy Treated L-cysteine. Further, the control sample was treated with a “sham” healer, who did not have any knowledge about the Biofield Energy Treatment. After that, both the Biofield Energy Treated and untreated L-cysteine samples were kept in sealed conditions and characterized using LC-MS analytical techniques.

Characterization

Liquid Chromatography-Mass Spectrometry (LC-MS) Analysis and Calculation of Isotopic Abundance Ratio

The liquid chromatography-mass spectrometric analysis of the L-cysteine was carried out with the help of LC-MS ThermoFisher Scientific, USA, equipped with an ion trap detector connected with a triple-stage quadrupole mass spectrometer. The column used here was a reversed phase Thermo Scientific Synchronis C18 (250mm × 4.6mm × 5micron), maintained at 25˚C. The diluent used for the sample preparation was methanol. The L-cysteine solution injection volume was 20μL and the analyte was eluted using acetonitrile (92%) + 0.1% ammonium acetate (8%) pumped at a constant flow rate of 0.8mL/min. Chromatographic separation was achieved using gradient condition and the total run time was 10 min. Peaks were monitored at 210 nm using the PDA detector. Mass spectrometric analysis was performed under ESI +ve ion mode. The total ion chromatogram, peak area% and mass spectrum of the individual peak which was appeared in LC along with the full scan were recorded.

The natural abundance of each isotope (C, H, N, O, and S) can be predicted from the comparison of the height of the isotope peak with respect to the base peak. The values of the natural isotopic abundance of the common elements are obtained from the literature [40-43]. The LC-MS based isotopic abundance ratios (PM+1/PM and PM+2/PM) for the control and Biofield Energy Treated L-cysteine (C3H8NO2S+) were calculated.

Percentage (%) change in isotopic abundance ratio = [(IARTreated–IARControl)/ IARControl)] × 100

Where IARTreated = isotopic abundance ratio in the treated sample and IARControl = isotopic abundance ratio in the control sample.

Results and Discussion

Liquid Chromatography-Mass Spectrometry (LC-MS)

The LC-SM of the L-cysteine showed a single major peak at retention time (Rt) of 1.96 minutes in both the chromatograms (Figure 1). The peak area of the Biofield Energy Treated sample (1960679.58) was significantly increased by 8.02% compared to the control sample (1815060.18). This indicated that the solubility of the Biofield Energy Treated L-cysteine might have increased compared to the control sample. The finding was supported by the published literature data [12].

The mass spectra of both the samples of the L-cysteine are shown in Figure 2. The mass spectra of both the samples at Rt of 1.96 minutes exhibited the presence of the molecular ion of L-cysteine (Figure 2) at m/z 122 (calcd for C3H8NO2S+, 122.03). Along with the molecular ion peak, low molecular fragmented mass peaks at m/z 105, 102, 87, 76, and 59 for C3H5O2S+, C3H2O2S•+, C3H5NO22+ or C3H5NS•+, C2H6NO2+, and C2H3O2+ were observed in case of both the samples (Figures 2 & 3). The experimental data were well supported by the published literature [44].

Isotopic Abundance Ratio Analysis

The L-cysteine samples showed the mass of a molecular ion at m/z 122 (calcd for C3H8NO2S+, 122.03) with 100% relative abundance in the spectra. The theoretical calculation of isotopic peak PM+1 for the protonated L-cysteine presented as below:

P (13C) = [(3 x 1.1%) × 100% (the actual size of the M+ peak)] / 100% = 3.3%

P (2H) = [(8 x 0.015%) × 100%] / 100%= 0.12%

P (15N) = [(1 x 0.4%) × 100%] / 100% = 0.4%

P (17O) = [(2 x 0.04%) × 100%] / 100% = 0.08%

P (33S) = [(1 x 0.08%) × 100%] / 100% = 0.08%

PM+1 i.e. 13C, 2H, 15N, 17O, and 33S contributions from C3H8NO2S+ to m/z 123 = 3.98%

Similarly, the theoretical calculation of PM+2 for L-cysteine was presented as below:

P (34S) = [(1 × 4.21%) × 100%] / 100% = 4.21%

PM+2, i.e. 34S contributions from C3H8NO2S+ to m/z 124 = 4.21%

The calculated isotopic abundance of PM+1 (3.98%) and PM+2 (4.21%) values was very close to the experimental values 4.3% and 4.6% (Table 1). From the above calculation, it has been found that 13C, 15N, and 34S have the major contribution to m/z 123 and 124.

The isotopic abundance ratio analysis PM, PM+1, and PM+2 for L-cysteine near m/z 122, 123, and 124, respectively of both the samples were obtained from the observed relative peak intensities of [M+], [(M+1)+], and [(M+2)+] peaks, respectively in the mass spectra (Table 1). The isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O or 33S/32S) and PM+2/PM (34S/32S) in Consciousness Energy Healing Treated L-cysteine was significantly increased by 41.86% and 32.39% compared to the control sample (Table 1). Thus, the 13C, 2H, 15N, 17O, 33S, and 34S contributions from C3H8NO2S+ to m/z 123 and 124 in the Biofield Energy Treated sample was significantly increased compared to the control sample.

The isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O or 33S/32S) and PM+2/PM (34S/32S) in the Biofield Energy Treated L-cysteine were significantly increased compared to the control sample. The changes in isotopic abundance could be due to the possible interference of neutrino particles via the Trivedi Effect®-Consciousness Energy Healing Treatment [16]. The altered isotopic composition in the molecular level of the treated L-cysteine might have altered the neutron to proton ratio in the nucleus. A neutrino is an elementary particle that interacts through the weak subatomic force and gravity. The neutrinos have the ability to interact with protons and neutrons in the nucleus, which indicated a close relationship between neutrino and the isotope formation [39,40]. The isotopic abundance ratios 2H/1H or 13C/12C or 15N/14N or 17O/16O or 33S/32S or 34S/32S would influence the atomic bond vibration of treated L-cysteine [45]. The increased isotopic abundance ratio of the treated L-cysteine may increase the intra-atomic bond strength, increase its stability, and shelf-life. The novel Biofield Energy Treated L-cysteine might have increased the stability, solubility, bioavailability, and shelf-life compared to the control sample. The novel Biofield Energy Treated L-cysteine would be more important to the food, cosmetic, pharmaceutical/ nutraceutical, and other industries compared to the control sample.

Conclusion

The Trivedi Effect®-Consciousness Energy Healing Treatment showed a significant impact on the chromatographic peak area and isotopic abundance ratio of L-cysteine. The LC-MS spectra of both the control and Biofield Energy Treated samples at Rt 1.96 minutes exhibited the mass of the molecular ion peak adduct with hydrogen ion at 122 along with low molecular fragmented mass peaks were also observed. The peak area of the Biofield Energy Treated sample was significantly increased by 8.02% compared to the control sample. The isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O or 33S/32S) and PM+2/PM (34S/32S) in the Biofield Energy Treated L-cysteine was significantly increased by 41.86% and 32.39%, respectively compared with the control sample. Hence, the 13C, 2H, 15N, 17O, 33S, and 34S contributions from C3H8NO2S+ to m/z 123 and 124 in the Biofield Energy Treated L-cysteine was significantly increased compared to the control sample. The changes in peak area and isotopic abundance ratios might be the cause of changes in nuclei possibly through the interference of neutrino particles via the Trivedi Effect®-Consciousness Energy Healing Treatment. The increased isotopic abundance ratio of the Biofield Energy Treated L-cysteine may increase the intra-atomic bond strength, increase its stability, and shelf-life. The novel Biofield Energy Treated L-cysteine might have increased the stability, solubility, bioavailability, and shelf-life compared to the control sample. The new form of Biofield Energy Treated L-cysteine would be a better and more stable precursor in the food, cosmetics, pharmaceuticals, personal-care products, additives to cigarettes (act as an expectorant), preventative or antidote for some of the negative effects of alcohol, acetaminophen overdose, clinically used ranging from baldness to psoriasis, excellent for the treatment of asthmatics by enabling them to stop theophylline and other medications, enhances the effect of topically applied silver, tin and zinc salts for preventing dental cavities. In the near future, this Biofield Energy Treated L-cysteine may play a better role in the treatment of diabetes, psychosis, cancer, and seizures.

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bolanblog · 1 year

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Pharmacology Viva and Practical Questions

Sir Abid

IV anesthetics

propofol metabolism why it is called milk of amnesia

action of ketamine

which other inhaled anesthetic works on NDMA receptors.

cyclophosphamide toxicity

Ketamine other name

NO MOA

Insulin structure batao 51 AA chore k

Glucose q mota krta ha

Old anesthetic name or usko log kese use krty thy

Propofol MAO

classification of all viral drugs A TO Z

Incretin functions

Other compounds similar to incretin

Stigliptin functions

Metformin 3 most imp side effects

Vit B12 active form

What we give in pernicious anemia

Shortest acting barbiturates

What is interferon and it’s moa?

Which drug is used for treatment of candida albican?

What do u mean by polyenes?

Moa of nystatin?

Dose of gabapentan and pregablin

Topirate seizure Ka elwa other use?

Acute malaria mein chloroquine ka elawa kon sa drug use hota hai?

2nd line Tb drug

Use of cifrofloxacin

What is 4th generation cephaloporin drug?

What is benzethine penicillin g and it’s uses

Domeclocycline and minocycle Ka uses other than antimicrobial?

What Is MoA of naicin vit b3

How nystatin make pores in ergosterol ?

What do U know about artemether

It natural and sysnthetic form

Opioid classification

Opiod receptors

Ethosuxamate calcium t chanell ko block krta hay konsi brain k part may

Myclonic epilepsy treatment Peripheral neuropathy causes treatment

Gaba pregablin ki metabolism kase hte

Eska action

Alfentanil kya hta

Methadon ka action

Uses

Mixed agonist antagonist ka name

Opiod poisoning mai kya dty...

Barbiturates ki calssification

Cyclophosphamide metabolism

Cyclosporine nature and action

TB 1 st and 2nd line drugs……. Why we give drugs combinely resistance k ilawa koi aur wajah

Antidirreal drugs

Drugs use for supra ventricular tachyarrethmia

Aminoglycoside moa other than protein synthesis

Uses of aminoglycoside

Diff bt azitho and clarithro

Sb sy ziada nephtotoxic konsi aminoglyco hai

Isonoazid molecular weight

Jb isonia?id dety to b6 ku km hty .

Tb regimens

Pka

Pka of aspirin

Volume of distribution

Amantadine k uses and MOA in parkinson

Parkinson treatment

Heart failure treatment

Pregnant woman with hypertension and cardiac failure DOC in treatment

Foscarnet side effects

Anti viral classification

Tb drugs primary nd secondary

Isonizid resistance

Which aminoglycoside is preferd ?

What do u care about when patient is taking streptomycin ?

Cuhsing syndrom causing drugs

Hepatitics c drugs other than interferon nd ribaviren

Polymerize chain reaction for hepatitis c

Why do we check genotype nd phenotye for hepatitis c

Active nd inactive forms of vitamin k

Def of half life, xenobiotics

P450 system

Atropine side effects and clinical indications

Fluoroqunilones

Difference between benzodiazepines and barbiturates

Drugs used to produce amnesia in patients

Use of Atropine with anesthetics

Opioid classification

Opiod receptors

Ethosuxamate calcium t chanell ko block krta hay konsi brain k part may

Myclonic epilepsy treatment

Tb drugs primary nd secondary Isonizid resistance

Which aminoglycoside is preferd ? What do u care about when patient is taking streptomycin ?

Cuhsing syndrom causing drugs Hepatitics c drugs other than interferon nd ribaviren

Polymerize chain reaction for hepatitis c

Why do we check genotype nd phenotye for hepatitis c

Active nd inactive forms of vitamin k

Biotransformation phases

Edrophonium

Mysthenia gravis , autoimmune disease

Rheumatid arthritis drug

Anticytokine drugs

Anakinrin

Uric acid drugs

Acetaminophene toxicity metabolite

Asprin uricosuria high dose of aspirin

asthma mn beta 2 ka mechanism of action..anidaireals.

Antacids.ppi.

TCAs names.

Azoles.names

Grisofulvin ka action

Blackwater fever konsi drug krati or..is mn kia hota ha.

Pregnancy mn save drugs konsi hn malaria wali.

Uterus pr beta 2 ka action..

NASEER SAHAB

Anti epileptics, hiv drugs, barbiturates, TCAs names, anti arrhythmics, benzodiazepines,

Biotransformation

Efficiency/potency defrnce

Antidepressants clas

Asthma drg clas

Laxative clas

Side effects of athma drg

Side effects of epinephrine

Antacid

Route of administration

Gout drg clas

Allopurinol moa

Morphine action

Serotonin drug

Lipid lowering drug action names and side effects

Diabetic drug name action and side effects

Hypo and hyperthyroidism drugs

Drug for hypoglycemia

What is pharma

Define drug

Gout k drugs

Therapeutic index

NorEpinephrine konse receptors pah zayda act karta hai

NSaids

Antiparkinson drug,types of dopamine recepters,

Theophylline MOA in asthma,serotonin agonists,prokinetic

Calcium saving diuretics

Antihypertensive drugs

First pass effect

Calcium channel blockers

Which beta blocker is used in eye

Practical

Definition syrup pills cream tincture spray

Prescription malaria wala ta

Long zinc oxide ointment wala ta

Sir Shahid

Potentiation, example, nature of levodopa, can carbidopa cross BBB,

Tcas k functions or wet pillow syndrome me kn c drugs use hoteen Levodopa

levodopa k sath carbidopa q dety

Levodopa k side effects

On off effect of levodopa

ziada tr antitussive poch rha ha

Or plant n animal derived drugs b pochy

Anti diabetic

Corticosteroids (orally)

DHT blocker

Atropine ( Deep )

Endotracheal tube k zarye konsa Drug

Atropine k contraindications

Why we dont treat children with Atropine

Antibiotics which act as anticancer

Albindazole and its action, konse worms pah act karta hai

What is Irritable boul syndrome

Drugs which are contraindicated in pregnancy

Metformin and its mechanism of action

B c drugs Mai Kiya fark hai

Tachyphylaxis 4 mechanism

Artimeten

Othotixic 4 drugs classes

5 fluorouracil and flucytocin difference and mechanism

Luminar amebiasis drugs

Epinephrine contraindications

Many more Jo yad b nai

Pro drug

Drug defi

Potentiation synergy additive poch rha

Diuretics dono poch rhy

Knsa diuretic ca++ saving hota knsa loss krwata

Loop diuretics or thiazides k nam

Hyperurecemia kn sy diuretics krwaty

Antidepressants ki classification

TCAs k nam

Centrally acting anti muscarinic or kahan use hoty morphine k 4 functions btao

Antiemetics

Sir Azhar

PPI may up regulation hotha ya down regulation mechanism

Adverse effect of cimetidine in males ,bone marrow sparing anticancer drug,bleomycin kis phase par act kartha hay Catecholamines synthesis, what happens to them in synapse Sympathetic and parasympathetic outflow

Pseudomembranous colitis

Penicillin side effects

Clinical indications of sympathomimetics

Glaucoma and drugs used in it

Growth hormones. Grow hormones receptor .growth hormone action. Uses. Why. When what who

Bas growth hormones A to Z

pharmacokinetics def

list all the factors affecting absorption of a drug

metronidazole uses

how pseudomembrane is formed.

effect of foods on drugs

IBS-c drugs

Metronidazole moa nucleic acid synthesis ko ks level py inhibit krta

Esky side effects

Nor epinephrine epinephrine ky uses side effect

Brain of GIT

Broad classification of receptors with examples

Diuretics classification

Potassium sparing side effects

Draw growth hormone receptors structure

Against k types

Partial agonist k example

Baqi yd nhi per easy the

Oxytocin mechanism of action

GI protective drugs explain

Ancids

Their side effects

Aspirin side effects

Bismuth subsalicylate function

Classification of sympathomimetics

Use of dubtamine

Cytoprotective drugs

Proton pump inhibitors

Binding sites of protein pump inbitors nd pump

Digoxin function

Nsaid induced ulcer how it occurs

Classification of antagonists

How physical antagonism works

Example of chemical antagonism

Theophylline functions on CNS

And Side effects

Mountain sickness

Clomiphene use in females + males

Growth hormone mechanism

Nitroglycerin kay ilawa which other drug administered sublingually?

Diuretic in pulmonary edema

Non nucleoside reverse transcriptase inhibitors?

Pencilline mechanism of action

Resistance

Define Pharmacology

Prodrug definition

Anacid definition

Symp parasym kb activate hoga

Symp chain

Why symp is diffused and para is not

Post sympthetic and parasympehtic nerves ki lenth ak hi kam or dosri ki zda qu hoti ha..ground level reason btani.ha.. Ion trapping

Anatacids ko systematic or unsystematic qu bolty ha

Phase 1 & Phase 2 reactions qu hoty

EXTERNAL

H1 antagonists or uses external bht poch rha ha ye or man function ye ha k bachon me sedation k lye dety

Anti spasmodic drugs

Antidiaarhoel

Uses of ondensetron

Uses of epinephrine

Anti malarial drugs

Specific uses of those

Antibiotic for prophylaxis of malaria

Anti tuberculosis regimen

2nd line drugs of tb

Moa of isonizide

General anesthetics

Captopril

Anti thyroid drugs

Oral contraceptive drug combination side effect

Misoprostol

Femoditine

H2 antagonist uses

Motion sickness and drugs

B2 signaling pathway

Methodone uses

Drugs used in Pulmonary edema

Hyocine diuretics

Digoxin k extra cardial side effects

Doxycycline uses

Drugs used in hyperthroidism

Penicllin resistance

Pulmonary edema causes

Carbonic anhydrase inhibitors names and functions

Antacids definition and systemic unsystemic effect

B agonist action on uterus

Tb regimens

Ach synthesis

Pethidine

Morphine moa Adverse effect contraindications

Pilocarpine adverse eff

Atropine antagonist

classify antifungal

fungal cellwall inhibitor names

classify laxatives

which anestheic is safe in pregnancy

classify anesthetic agents

diff between amides and esters

diff between benzodiazapenes and barbiturates and how to deal with there toxicities

Biotransformation

Pilocarpine side effects

Tramadol side effects

Difference between benzodiazepine and barbiturates functions

Antidote of benzo

Which is more harmful to heath benzo or barbo

Explain eith reason

Heparin antidote

What is rifampin

Sides effects

Ethambutol side effects

Aminoglycoside drugs

Tobramycin side effects

Baqi yad naya

Plant derived drugs

Scopolamine k side effects

Anti diarrheals

Why drug combination is used in tuberculosis

Pencillin kb or kis ne discover kia

Emperical therapy

Synergism

Symptoms of hydantoin syndrome

Drug used prior to anesthesia

Citalopram side effect

Benzodiazepen side effect

Digoxin side effects

Cough suppressant plus asthma and COPD drugs

Classify alpha receptor blockers

TB k drugs

Tetracyclins k side effects

Cefixime konse generation ma atha hai, its anti bacterial spectrum

Streptomycin k side effect

Aminogylcosides k classification

Isoniazid mechanism of action nd side effects nd why do we give vitamin 6

Atypical nd typical antipsychotics

Side effect of haliperiddol

Neuroleptic malignant syndrom

Malignant hyperthermia

What is the side effect of succinyle choline

Functions of epinephrine

What is antagonism Drugs of cns having effect on libido , fertility

Bromocriptine effect in Raynaud's phenomenon

What is ergot alkloid

Side effect of ergot

Erythromyalgia main effect in which diseases

Alpha recepters location

Receptor in non pregnant uterus

cronry steal phenomna and drug

sigma rcptor opiods

bupronorpine nulbupine. ik hath pe bupronorpine dosre hath pe nulphine total body effct

vrmpil action on paltltles and insulin

wlof parkinsons disease

ppar gama on lipid or insulin

pentidine specific side effct

iron antidoe and iron rcptor and iron pumps

Plants alkaloids

Adverse effects of quinine,drug for worms

Tb may drug combination q dathy hay

#3rd year #MBBS #Medical Sciences #Medicine #Pharmacology #Viva #Viva Question #Medstudent #Bolan Medical College #Quetta

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richamishra01 · 1 year

Text

What Cause Liver Failure

Signs and Symptoms of liver disease

Jaundice (yellow pores and skin and eyes)

Dark urine

Nausea

Vomiting

Chronic fatigue

Itchy pores and skin

Easy bruising

Swollen legs

Seek hospital therapy when you have any of those signs or chronic symptoms and symptoms that fear you.

Acute liver failure may be as a result of many extraordinary things, even though the precise purpose can be unknown in a few cases. Possible reasons are:

. Viral infections – like hepatitis A, B or E

. Reactions to prescription medicinal drugs together with antibiotics, antidepressants, anti-seizure medicinal drugs

. Reactions to few natural medicinal drugs and supplements

. Overuse of positive capsules like acetaminophen (Tylenol)

. Autoimmune situations like autoimmune hepatitis

. Metabolic problems together with Wilson’s disease

Treatment and prevention of liver failure

You can reduce your risk of liver failure with the aid of using taking easy steps such as:

. Eating a wholesome food regimen wealthy in culmination and greens at the same time as reducing lower back on fatty foods.

. Maintaining a wholesome weight.

. Avoiding alcohol consumption.

. Getting vaccinated towards hepatitis A and B.

. Following guidelines whilst the usage of medications.

. Practicing appropriate private hygiene.

. Having ordinary physical examinations together along with your doctor.

Dr. Ninad Deshmukh is one of the best Liver transplant surgeon in pune India. He has performed more than 100 liver transplant surgeries as a Chief Surgeon. Currently, he is available at Deenanath Mangeshkar Hospital pune. He is an expert in all types of liver transplants and is the preferred choice for domestic as well as international patients. NewLife Gastro Liver Clinic is one of the best liver transplantation clinics in India. If you have any liver related problems ,Dr Ninad Deshmukh is the best doctor for you. Book your Appointment Now!

#livertransplant #livertranspalntsurgeoninpune #liver specialist #liver failure

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dayaramchemicals · 2 years

Text

A Brief Guide to Acetonitrile: What it is And What It's Used For

If you’re like most people, you probably didn’t even know what acetonitrile was before you started reading this article. But it’s definitely worth knowing about because it has so many uses that can help in your everyday life. This guide explains what acetonitrile is and the different applications of the same. Read on to find out.

First Off, What is Acetonitrile?

Acetonitrile is a clear, colourless liquid with a characteristic, pungent odour. It is miscible with water and most organic solvents. It easily gets confused with acetone, however the acetone specification is pretty different from that of acetonitrile. Even though acetonitrile and acetone are organic compounds, acetonitrile is a nitrile compound and acetone is a ketone.

Applications of Acetonitrile:

These are the popular applications of Acetonitrile:

Solvent:

Acetonitrile is a polar solvent that's often used as a laboratory solvent because it dissolves many organic compounds. It's also used in the production of plastics, adhesives, and coatings. And because it has a high boiling point, acetonitrile is often used as a heat transfer fluid. Acetonitrile is extremely flammable so it should never be stored near open flames or hot surfaces.

2. Manufacture of Pharmaceuticals:

Acetonitrile is used as a solvent in the manufacture of pharmaceuticals, including antibiotics, anaesthetics, and antineoplastic drugs. It is used as a reactant in the synthesis of drugs and other chemicals. Pharmaceutical products that use acetonitrile include Zyvox (linezolid), Tylenol PM (acetaminophen), Dermoplast spray (diphenhydramine), Buspar (buspirone), Penicillin V potassium, and Terramycin ophthalmic ointment.

3. Manufacture of Batteries:

Acetonitrile is used as an electrolyte in the manufacture of batteries. It helps to increase the conductivity of the battery and improve its performance. Additionally, acetonitrile is used as a solvent in the production of lithium-ion batteries, which are commonly used in electronic devices such as laptops and cell phones.

4. Manufacture of Perfumes:

According to the acetonitrile manufacturers in India, the making of perfumes and cosmetics is one of the most important uses of acetonitrile. This chemical is used as a starting material or intermediate in the production of a variety of perfume ingredients, including esters, ketones, and aldehydes. Acetonitrile is also used to make synthetic musks, which are used as fragrance fixatives in perfumes and cosmetics.

5. Manufacture of Pesticides:

Acetonitrile is used as a solvent in the manufacture of pesticides. It helps to dissolve other materials so that they can be mixed together evenly. This ensures that the final product is effective and safe. Acetonitrile is also used as a reaction medium in the production of some pesticides.

Acetonitrile has many applications that are listed above, which is mainly attributed to its stability and low toxicity. In today’s modern world, acetonitrile has become such an important compound today. Contact a supplier to know about the acetone specification and how it differs from acetonitrile.

#acetonitrile manufacturers in india #acetonitrile #acetone specification

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emptyanddark · 2 years

Text

ibuprofen is tumblr's drug. idk how widespread the usage actually is but if you do often/sometimes use it:

General advice:

Don't take ibuprofen on empty stomach. As any other NSAID, it can cause gastric irritation. For higher doses & forstronger NSAIDs (e.g. aspirin,naproxen, diclofenac, etodolac, etoricoxib) you should have an actual meal before taking the medicin.

If you use it for the occasional pain relief try paracetamol (acetaminophen) instead; if ineffective try formulations of paracetamol+caffeine, as it has synergistic effect. Paracetamol is not anti-inflammatory like ibuprofen and can be used in cases when NSAIDs are not recommended/contraindicated (see next).

The dosage is up to 400mg every 4 hours. Use only as necessary. Do not exceed 3200mg a day.

Do not combine w other NSAIDs. If symptoms persist you may combine w paracetamol.

Unless directed by a doctor, do not give to babies younger than 6 months.

Precautions

Asthma: if you have preexisting asthma you may have aspirin-sensitive asthma (AIA, AERD). This means you may have a respiratory reaction when taking NSAIDs because these medication block the same pathway resulting the synthesis of mediators that cause bronchocostiction & spasms. This condition may be fatal.

You have hypertension

Pregnancy: avoid as much as possible. Do not use in late pregnancy (3rd trimester). Breastfeeding- not recommended, but you can take right after you breastfeed.

Renal impairment, heart failure, fluid retention, liver impairment

Elderly

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siglerprescriptiondrugcards · 3 years

Text

Sudafed

Ingredient: Pseudoephedrine HCl (PSE), phenylephrine (PE), dextromethorphan HBr (DXT), acetaminophen (APAP), guaifenesin (GUA), naproxen sodium.

Dosage Form:

Sudafed Congestion: PSE 30 mg.

Sudafed 12 Hours: PSE 120 mg.

Sudafed 24 Hours: 240 mg.

Sudafed PE Congestion: Phenylephrine 10 mg.

Sudafed PE Pressure & Pain: PE 5 mg, APAP 325 mg.

Sudafed 12 Hour Pressure & Pain: PSE 120 mg, naproxen sodium 220 mg.

Sudafed PE Pressure, Pain, & Cough: PE 5 mg, APAP 325 mg, DXT 10 mg.

Sudafed PE Pressure, Pain, & Cold: PE 5 mg, APAP 325 mg, DXT 10 mg, and GUA 100 mg.

Sudafed PE Pressure, Pain, & Mucus: PE 5 mg, APAP 325 mg, GUA 200 mg.

Children’s Sudafed PE: Each 5 mL contains PE 2.5 mg.

Children’s Sudafed Nasal Decongestant: Each 5 mL contains PSE 15 mg.

Children’s Sudafed Cold & Cough Liquid: Each 15 mL contains PE 2.5 mg and DXT 5 mg.

FDA Indication/Dosages:

Products containing pseudoephedrine or phenylephrine are indicated for the temporary treatment of sinus and nasal congestion.

Products containing dextromethorphan are indicated for the temporary treatment of cough due to minor throat irritations.

Products containing guaifenesin are indicated for the temporary relief of cough due to chest congestion.

Products containing acetaminophen are indicated for the temporary relief of minor pain and the reduction of fever.

Adults: 1-2 tablets/caplets every 6 hours as needed. Do not exceed 8 tablets in 24 hours.

Capsules, Sustained Relief (Adults): One capsule every 12 hours or 24 hours. Do not exceed 240 mg per 24 hours.

Children 6-12 years of age: ½ tablet or 1 teaspoonful every 4-6 hours. Do not exceed 4 teaspoonfuls per 24 hours.

Pharmacology: Pseudoephedrine and phenylephrine stimulate α-1-adrenergic receptors in the smooth muscle causing vasoconstriction. This vasoconstriction decreases swelling in the nasal passages and relieves congestion. Acetaminophen relieves pain by inhibiting prostaglandin synthesis in the CNS and through a peripheral synthesis in the CNS and through a peripheral action by blocking pain impulse generation. The CNS effects also lower the elevated temperature set-point which results in fever reduction. Dextromethorphan is structurally similar to codeine and has equal antitussive properties without CNS effects of addiction. It depresses the cough reflex center in the medulla oblongata without decreasing ciliary function. Its effects last for 5 or more hours.

Evaluation: Decongestants may cause severe hypertension when combined with furazolidone or monoamine oxidase inhibitors. Urine alkalinizers including sodium bicarbonate may increase toxicity of decongestants. Do not use in patients with high blood pressure, diabetes, heart disease, and thyroid disease except under the direction of a physician. Prolonged use of acetaminophen at therapeutic doses may cause hepatotoxicity especially in alcoholics. Hepatotoxicity potential is increased when used with hydantoins, sulfinpyrazone, or alcohol. Pregnancy Category B.

Contraindications/Precautions: Decongestants may cause severe may cause severe hypertension when combined with furazolidone or monoamine oxidase inhibitors. Urine alkalinizers including sodium bicarbonate may increase toxicity of decongestants. Do not use in patients with high blood pressure, diabetes, heart disease, and thyroid disease except under the direction of a physician. Prolonged use of acetaminophen at therapeutic doses may cause hepatotoxicity especially in alcoholics. Hepatotoxicity potential is increased when used with hydantoins, sulfinpyrazone, or alcohol.

Adverse Effects: May cause nervousness, dizziness, or sleeplessness.

Patient Consultation:

Ask the patient about their symptoms; they may not need all the components of this combination.

Ask the patient about their medical history including heart disease, hypertension, thyroid disease, and drug therapy.

Contact a physician if no improvement is seen after 7 days or in the presence of a high fever.

#sigler nonprescription drug cards #10th edition #sudafed #pseudoephedrine hcl #pse #phenlyephrine #pe #dextromethorphan #dxt #acetaminophen #apap #guaifenesin #gua #naproxen sodium #allergy relief #cold relief #drug facts

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treatmentofacutecystitis · 3 years

Text

Cystitis and what pain killers may help

Types of cystitis

Cystitis is inflammation of the walls of the bladder. Most often it is accompanied by inflammation of the urethra. Bladder infections come in different forms.

Naturally:

· Non-infectious caused by irritation of the bladder lining from high doses of drugs, spicy food, alcohol, or hypothermia.

· Infectious, caused by various infectious agents.

Depending on the course of the disease:

· Acute, which occurs for the first time and is accompanied by acute pain.

· Chronic that occurred several times in the same patient. The symptoms are expressed more weakly. In the neglected variant, however, concomitant diseases of the kidneys and ureters can occur.

What pain relievers for cystitis?

No easy treatment gets rid of the signs and symptoms and signs and symptoms of interstitial cystitis, and no one treatment works for anyone. You could want to strive numerous treatments or combos of remedies before you locate an approach that relieves your signs. Your doctor or pharmacist can advise you on how to treat yourself and recommend taking pain relievers to relieve symptoms of a cystitis. You may need to try different treatments or combinations of treatments before finding an approach that will relieve your symptoms.

Oral medications that may improve the signs and symptoms of cystitis include:

· Non-steroidal anti-inflammatory drugs (NSAIDs) to relieve pain, such as ibuprofen or naproxen.

· Tricyclic antidepressants, such as amitriptyline or imipramine, to relax the bladder and block pain.

· Antihistamines such as B. Loratadine, which may reduce the urge to urinate, reduce the frequency of urination and other symptoms.

Your doctor may suggest that you take over-the-counter pain relievers to control mild bladder pain, provided there are no contraindications:

· Paracetamol

· Aspirin

· Ibuprofen

· Naproxen

Talk to your doctor if you think you need stronger pain relievers for a cystitis. If you're in severe pain, your doctor may need to prescribe opioid pain relievers or pain relievers, such as acetaminophen with codeine. Drugs from the NSAID group inhibit the synthesis of enzymes that cause tissue inflammation. NSAIDs pain relievers for cystitis, with a bladder infection, drugs of this group work in several directions: NSAIDs have an antipyretic, analgesic and anti-inflammatory effect. It should be remembered that NSAIDs do not eliminate the harmful micro flora - the infection itself, which in most cases is one of the Gram-negative bacteria.

Diclofenac pain reliever for cystitis the use of non-steroidal anti-inflammatory drugs (NSAIDs) could potentially reduce the use of antibiotics. In a randomized double-blind study.

Symptoms of cystitis?

The common symptoms of cystitis are, Symptoms are most pronounced in middle-aged people, and insignificant in the elderly and children, which makes it difficult to diagnose the disease. A distinction is made between the following symptoms:

· Pain or stubborn sensation when you urinate

· Frequent urination is required, but very little urination is done each time

· dark, strong-smelling urine

· blood in your urine

· pain in your belly or lower back

· feeling feverish

· Urinary incontinence

Treating cystitis at home

If you have slight signs and symptoms which have just come on, then there are a few methods you may deal with your cystitis at home and help resolve the infection:

· drinking lots of water

· Over-the-counter painkillers such as ibuprofen and paracetamol are taken

· refraining from sex

· Your discomfort with a hot water bottle is admirable

· avoiding alcohol, fruit juice and caffeine

In case your cystitis persists for a number days then you definitely have to be searching for scientific assist - if left untreated, the contamination ought to spread to your kidneys, making it a medical emergency. In case you develop a high fever, severe pain or in case your symptoms get worse you need to see a physician right away.

Conclusion

All drugs, including pain relievers without prescription, have side effects. Ibuprofen and other NSAIDs have certain risks associated with their use. Ibuprofen can damage kidney function, either through direct injury or by suppressing some of the inflammatory changes in the body that are a reasonable and helpful response to an infection. Always consult a doctor before using any medication or dietary supplement for more than a few days. Click on the link for a more in-depth analysis here: https://schmerzmittelshop.com/2021/02/02/schmerzmittel-bei-blasenentzuendung/

Schmerzmittel bei Blasenentzündung

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