#nrf1

[the-vitamins-shop]

What is Protandim Tri-Synergizer and What can it do for You?

#The Vitamins Shop #Protandim #Protandim Tri-Synergizer #Nutrigenomics #vitamins & supplements #Nrf1 #Nrf2 #NAD #Glutathione #antioxidant #health #health and wellness #prevention #healthy lifestyle

[fruit-worm-papers]

NFE2L1/Nrf1 serves as a potential therapeutical target for neurodegenerative diseases

http://dlvr.it/T0yw5G

[synergydentalgroup]

Biohacking Our Genes Using Celsus One® and Nrf2 Activation

HACKING THE GENETIC CODE TO HELP MY PATIENTS LIVE A PREVENTIVE LIFESTYLE

in my practice, I am a “biohacker” helping my patients become healthy at the cellular level, using biomarkers, saliva tests, blood work, and new-age supplements; hacking the genetic code to help my patients live a preventive lifestyle. I often tell my patients that their mouth is an indication of their internal body tissue health. Incorporating the genetic analysis from the Celsus One™ report helps me establish personalized health recommendations utilizing genetic risk factors related to the oral and systemic inflammatory response.  

Utilizing genetics in conjunction with products that activate NRF1 (Nuclear respiratory factor 1) and Nrf2 (nuclear factor erythroid 2 (NFE2)-related factor 2) pathways to create internal cellular molecules can turn back the aging process and become part of a full preventive program. Considering that there are over 200 disease processes that start with inflammation, it’s exciting that Celsus One™ shows 8 biomarkers associated with periodontal, diabetes, cardiovascular and arthritis.

Since the lab results show the patient’s own unique genetic makeup, health providers can educate patients on how the genotypes of certain gene markers affect their long-term systemic health. The three innate gene markers: Beta-defensin 1 (DEFB1), CD14 (CD14), and Toll-like receptor 4 (TLR4), and five acquired gene markers: Tumor necrosis factor-alpha (TNF-alpha) Interleukin 1 (IL1), Interleukin 6 (IL6) Interleukin 17A (IL17A) Matrix Metallopeptidase 3 (MMP3) have different variations in degree of severity in association with inflammatory disease processes. The variation for personalizing patient care helps me to decide on periodontal therapy adjuncts, frequency of periodontal recare, environmental challenges, and ultimately how to best educate my patients in being proactive. My patient’s feel empowered knowing they can potentially influence the effect of their genetics.

Protandim®, Nrf2 Activator™, has 5 patents with over 25 independent peer reviews found on www.pubmed.gov, and is one of my favorite product lines that I have incorporated into my practice. (Previously written: It works at the cellular level to activate ATP and mitochondria and has been clinically proven to reduce oxidative damage by 40% within 30 days). Correction: Protandim Nrf1 activator increases ATP and Mitochondria function and Nrf2 activation reduces oxidative stress by 40% within 30 days. Oxidative stress (free radical damage) is a root cause of all disease processes. Nrf2 is a protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. The Nrf2 protein remains dormant within each cell of our body, unable to move or perform its task until released by an Nrf2 activator.

The Nrf2 genetic pathway turns on over 400 transcription genes such as GSTP1, which is related to detoxification. Prior to the Protandim® product line, Sulforaphane, found in broccoli sprouts, was the “gold” standard of naturally occurring Nrf2 activators. Studies have shown that Protandim® Nrf2 Activator™ is 135-fold more powerful than Sulforaphane. Protandim® Nrf2 is composed of 5 herbs that each in their own right have an ayurvedic effect, but also have been proven to work better together synergistically rather than each component individually. A second activator, Protandim® NRF1, works as a “One-Two Punch,” increasing ATP, mitochondrial DNA transcription, replication activity, and quality of sleep.

I am successfully helping my patients utilize their personalized Celsus One™ results to biohack their genetics, using proven modern tools such as Nrf1 and Nrf2 activators to improve their environments. Reducing systemic inflammation using the most modern science and supplements helps me stay on the cutting edge and I am definitely a BIOHACKER for life.

To find out more about this topic please go to http://www.synergydentalgroup.net/ and contact Dr. Kimberly Hubenette.

**To learn more about becoming an OralDNA Provider: Text “OralDNA” to 43766**

[aladay]

NRF2, NRF1, and NAD: Pros and Cons

NRF2, NRF1, and NAD: Pros and Cons NRF2, NRF1, and NAD are three important molecules that play a role in cellular protection and repair. NRF2 is a transcription factor that regulates the expression of genes involved in antioxidant defense, while NRF1 is a similar transcription factor that regulates genes involved in DNA repair. NAD is a coenzyme that is involved in a variety of cellular…

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[mcgregorwilliam]

Prodentim Critiques New Revelation By Actual Customer Exposes The Truth About Pro Dentim Benefits

This drawback may be fastened by dietary modifications or utilizing an oral well being booster, and utilizing a complement sounds easier than altering the entire food plan. ProDentim is a dietary supplement that helps to maintain your oral hygiene. It has several pure elements that assist to maintain your oral well being and supply multiple well being advantages.

This dose is rapid and effective since it is substantially larger than that of other generally utilized probiotic sources.

One can consume the recommended every day dosage at any time of the day with a beverage of your selecting.

Although it is stuffed with bacteria, many of the bacteria in your mouth is innocent.

Since the composition is kind of entirely natural, and also you do not have to worry about affected by any unwanted side effects or allergies.

These oral probiotic tablets are made within the United States utilizing one of the best manufacturing strategies.

Visiting a licensed dentist prior to consuming the product is strongly advised by our team.

The method consists of probiotic strains that are clinically confirmed to be trustworthy and efficient. B. Lactis BL-04- Bifidobacterium lactis BL-04 is a probiotic that produces lactic acid and acetic acid. According to a different Washington City Paper review of ProDentim B. Lactis BL-04 balances the concentration of fine bacteria in the mouth and also helps a healthy respiratory tract and immune function. This strain of micro organism is also confirmed to enhance gastrointestinal function. ProDentim is a whole oral hygiene supplement for the tooth and gums.

Outcomes And Longevity Of Prodentim Dental Care Pill

It can alleviate symptoms of toothache, sore throat, and the common chilly. So if you’re getting bothered by the regular use of toothpaste and other merchandise, which don’t present any outcomes, you must give ProDentim a strive. You can solely get to know if the product is giving desired returns when you use it for a considerable time. And even after that, they can get you a money-back assure if you’re unhappy with the product. You can get one bottle of the tablets for 30 days’ supply at $69. Most of the customers start noticing visible improvements within the complexion of their teeth within 2 three weeks of use.

Benefits Of Prodentim Nrf1 Synergizer

You should brush your tooth twice or thrice daily to take away plaque and other meals particles. All orders, no matter how many bottles are included, are shipped free of charge, and this provide is legitimate for a restricted time only. These books price $109 every, but they're free for ProDentim clients. The benefits increase to the digestive system too, and the probiotics additionally enhance digestion and manage weight. They save from frequent digestive issues like bloating, gas, nausea, constipation, and different points. It will enhance the looks of enamel and possibly give you the smile of your desires, along with managing oral points. Using prodentim candy , you'll have the ability to maintain your tooth and gums in good well being, avoid gum disease, and hold them in good condition with ease. This all-natural capsule has a unique combination of components that assist to prevent cavities from forming.

#prodentim #prodentim reviews #prodentim pills #prodentim benefits #prodentim candy #prodentim united states

[zehub]

Ces insectes font repousser leurs muscles à la demande

Pour économiser de l'énergie en hiver, certains coléoptères ont développé une stratégie d'une efficacité sans égale. Ils se défont de tous leurs muscles. Pas grave puisqu'ils peuvent les faire repousser sans le moindre effort.

  Nathalie Mayer Publié le 22/07/2022

  ----------

NDÉ

L'étude :

  Reversible mitophagy drives metabolic suppression in diapausing beetles | PNAS, 19.07.2022 https://www.pnas.org/doi/abs/10.1073/pnas.2201089119

  Significance

Metabolic suppression helps dormant insects survive prolonged periods without food. Although metabolic suppression is widespread, we do not understand the mechanisms underlying shifts to a hypometabolic state. We show that metabolic suppression in dormant Colorado potato beetles is a consequence of shifts in flight muscle mitochondrial homeostasis. Dormant beetles activate mitophagy in their muscle, degrading most mitochondria, thereby reducing their metabolism. In anticipation of the end of dormancy, beetles regrow their flight muscle mitochondria. We show a unique pattern by which beetles regulate mitochondrial homeostasis to contribute to whole-animal shifts in energy metabolism. Other adult insects also degenerate their flight muscle during dormancy; thus, it is possible that remodeling flight muscle mitochondrial homeostasis to save energy is a widespread strategy.

Abstract

Many insects enter a state of dormancy (diapause) during winter in which they lower their metabolism to save energy. Metabolic suppression is a hallmark of diapause, yet we know little about the mechanisms underpinning metabolic suppression in winter or how it is reversed in the spring. Here, we show that metabolic suppression in dormant Colorado potato beetles results from the breakdown of flight muscle mitochondria via mitophagy. Diapausing Colorado potato beetles suppress their metabolism by 90%, and this lowered metabolic rate coincides with a similar reduction in flight muscle mitochondrial function and density. During early diapause, beetles increase the expression of mitophagy-related transcripts (Parkin and ATG5) in their flight muscle coincident with an increase in mitophagy-related structures in the flight muscle. Knocking down Parkin expression with RNA interference in diapausing beetles prevented some mitochondrial breakdown and partially restored the whole animal metabolic rate, suggesting that metabolic suppression in diapausing beetles is driven by mitophagy. In other animals and in models of disease, such large-scale mitochondrial degradation is irreversible. However, we show that as diapause ends, beetles reverse mitophagy and increase the expression of PGC1α and NRF1 to replenish flight muscle mitochondrial pools. This mitochondrial biogenesis is activated in anticipation of diapause termination and in the absence of external stimuli. Our study provides a mechanistic link between mitochondrial degradation in insect tissues over the winter and whole-animal metabolic suppression.

  [Image] via Recherche Google images

[marissahughes]

🌺Protandim® Nrf1 Synergizer™

What does Nrf1 Do? Just because you’re getting older doesn’t mean you have to feel like it. Protandim® NRF1 Synergizer™ helps your cells produce more mitochondria, so you feel younger and more energetic from the inside. It’s a new breakthrough in nutrigenomics that helps bring back that youthful feeling to your body.

https://www.youtube.com/watch?v=lYNrsagaXqY

https://hughesmarissa.lifevantage.com/us-en/shop/protandim-nrf1

#nutrigenomics #biohackers #protandim #nrf1 #health #business

[crispydreamwinnerthing-blog]

Está demostrado que la activación #Nrf2 y #Nrf1 puede aliviar los dolores y molestias de #artritis . Una desinflamación en conjunto con una mejor #saludcelular son parte de los beneficios que obtendrá. Usted pierde una cantidad enorme de #celulas todos los días empezando con el solo hecho de respirar. ¿Eliminarías el 40% de esa oxidación si pudieras? Pues eso ya es posible con la única terapia que lo puede hacer, la terapia Nrf2. Y de forma natural y sin efectos secundarios. #AR #artritisreumatoide #Fibromialgia #fibromyalgia #newcell #celulasnuevas #estresoxidativo #oxidativestress #reuma #reumatología #reumatologista #espondilitisanquilosante #livelonger #nomasdolor #nomorepain #lifequality #calidaddevida #terapia #therapy #Biohacking #nutrigenomica #nutrigenomic https://www.instagram.com/p/BwO63BmH35e/?utm_source=ig_tumblr_share&igshid=ducismzq6rnu

#nrf2 #nrf1 #artritis #saludcelular #celulas #ar #artritisreumatoide #fibromialgia #fibromyalgia #newcell #celulasnuevas #estresoxidativo #oxidativestress #reuma #reumatología #reumatologista #espondilitisanquilosante #livelonger #nomasdolor #nomorepain #lifequality #calidaddevida #terapia #therapy #biohacking #nutrigenomica #nutrigenomic

[amylynnmilstein]

WE ARE LIVING LONGER BUT NOT BETTER ‼️ Let me help you: 💥REDUCE YOUR OXIDATIVE STRESS 💥REBUILD CELL AND DNA DAMAGE 💥SUPPORT GENETIC VARIANTS 💥SUPPORT NUTRITIONAL DEFICENCIES 💥SLOW DOWN THE AGING PROCESS 💥EXTEND TELOMERES 💥REDUCE RISK OF DISEASE AND MORE.... it's not as expensive as you would think and you will live longer with a better quality of life 💞 #uforiascience #dnahealth #genehealth #nrf1 #nrf2 #nad #cbd #naturalhealing #biohacker #nutrigenomics #oxidativestress #geneticvariants #nutritionaldeficencies #aging #disease #telomeres #dnadamage #cellrepair #healingfromwithin #tiptuesday (at My Office) https://www.instagram.com/p/B37A_ldnC0u/?igshid=vyuqft6rlmzd

#uforiascience #dnahealth #genehealth #nrf1 #nrf2 #nad #cbd #naturalhealing #biohacker #nutrigenomics #oxidativestress #geneticvariants #nutritionaldeficencies #aging #disease #telomeres #dnadamage #cellrepair #healingfromwithin #tiptuesday

[nanlicia]

ransom is graduating???

The night is quiet, still, and cool. There’s a breeze rustling the leaves and caressing Justin’s face and there’s a cloud of smoke fluttering in it as Justin exhales. 

There’s something comforting about the way the haus creaks below him, the patch of soft yellow light on the grass below from where someone left the kitchen light on, the sight of the frisbee Whiskey and Dex had been throwing around earlier that afternoon sitting at the base of the tree in the front yard, the bbq pit sitting off to the side and Justin can almost still smell the burning charcoal from earlier.

It’s the feeling of youth in all its splendor, and community in all its safety, and joy in all its volume, echoing in the shadows at midnight of what the day had been at 2pm. 

Maybe that’s what life is meant to be, Justin thinks - whispers of the times past, hints of the times to come, gnawing at your soul and baiting your memory to hold on as long as possible without allowing what comes next to slip by uncherished. 

Justin takes another moment to look down the street and convince himself that he’ll never forget this, he’ll never let go. 

There won’t be another place he feels so cared for, so free, or so safe. There won’t be a single ‘nother place like this, and he’s going to remember every second, every scent, every fleeting touch, and he’s going to etch it into the very foundation of his soul and he’s going to carry this haus with him in everything that comes next - these people in this haus on this street in this school in this town - they’re going to be everywhere he is from here on out. 

He’s gonna take them to Boston, and he’s gonna take them to medical school, maybe, and he’s gonna take them to his parent’s home, and every part of him that still sits here on this roof for the rest of eternity will smile knowing that every part of him that accomplishes amazing things will have this haus and these people with him when he does and that - there’s something comforting in that. 

#im literally writing to get the bad shit out this is so bad it's just words on a page that don't mean anything!!! #ughhhhhhh #this is a warm up pls ignore it #maybe its the start of a scene and derek will come pull justin out of his head #maybe it's just a warm up to get in justin's head myself idk #idk what im doing im jjust trying to write today and this is what i have so far #ahhhhhhhhhhh #i need to write today and i can't im just turning out garbage!!!!!! #tagging it as #mine #i guess #nrf1

[biohackerbarcode]

Oxidative stress can damage cells, proteins, and DNA, which can contribute to premature aging and health concerns. Protandim® Nrf2 Synergizer®, also known as the Little Yellow Activator, activates your body’s antioxidant production and has been shown to reduce oxidative stress by 40% in just 30 days.* LifeVantage’s first Protandim product was the discovery that changed…

#antioxidants ness immuneHealth digestionHealth skincare haircare Stacks ICbright ActivateDailyWellness NRF1 NRF2 Prodandim Amiga Synergizer #[email protected] 💙

[the-vitamins-shop]

#The Vitamins Shop #Energy #Nutrigenomics #Biohacking #Antioxidant #NAD #Mitochondria #Anti-Aging #Longevity

[durhamcoolblogmaster]

Win a 30 day supply of this Amazing Health Supplement!Protandim® Tri-Synergizer™*

Protandim Nrf2, NAD, and NRF1 Synergizers effectively reduce oxidative stress, support mitochondria function, increase sirtuin activity, and target cell signaling pathways to fight the effects of aging.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

[rednaturas-blog]

RedNatura

RENUGEN ®

RENUEVA TUS GENES

RENUGEN ®

Presentación: frasco con 30 tabletas.

Ingredientes

Alga Afa.

L Glutatión Reducido.

Semillas de Uva.

Quercetina.

Ajo Negro.

Brócoli.

Beneficios

Disminuye la oxidación celular hasta un 30%.

Estimula la producción de las proteínas NRF1 y NRF2.

Aumenta los Niveles de Glutatión en el organismo.

Estimula la producción de manera natural tus propios antioxidantes.

Reduce la inflamación crónica.

Ayuda a producir células madre.

Modo de Empleo:

tomar una tableta al día.

Contraindicaciones: No consumir durante el embarazo ni la lactancia.

No ingerir si es sensible o alérgico a alguno de los componentes de la fórmula.

[hammerofdestruction]

It’s a good day. #LifeVantage #BioHack #NRF1 #eliteacademy (at Anaheim Convention Center)

#lifevantage #biohack #nrf1 #eliteacademy

[peterbuiltmedia]

LifeVantage | Where Nutrigenomics Go To Work

http://enrollme.lifevantage.com

#Vimeo #lifevantage #nrf2 #nrf1 #products #opportunity #protandim #truescience #physiq #axio