Note: Drizzler itself isn't as important but the torpedo's are.
Of course it depends on the situation and weapons, but do your best to take them out. FYI taking out a single Flyfish basket does make them shoot less missiles so it helps a lot if you can't get both
This is the Killer Wail of Flyfish Obliteration. Reblog the Killer Wail of Flyfish Obliteration to keep Flyfish away from your shifts and to ensure your bombs stay in the goddamn missile launchers when you hit them.
It's been approximately one year since Big Shots were the first Boss Salmonid to get directly nerfed in a balance update, and year later that is still as ridiculous as it was at the time considering that Flyfish are right there.