#cbd ales

[cbd-nimes-anonymseeds]

CBD HHC NIMES ANONYM SEEDS PUFF DE HHC IMPORT USA

#CBDNimes #anonymseeds #cbd nimes #cbd #cbd flowers #cbdcoconutoil #cannabiscommunity #cbd ales #cbd products #hemp #saveoncannabis #best cbd e liquid uk #best cbd capsules for pain relief uk #cbdproducts #delta8 #cbd capsules for sale #cbdisolate #cbd capsules 1000mg #cbd capsules 50mg uk #cbd oil #huilecbd #huile CBN #hhcnimes #magasincbdnimes #Boutiquecbdnimes

[budandtender]

The Role of Endocannabinoids in Regulating Motor Neuron Disease/Amyotrophic Lateral Sclerosis

International Alliance of ALS/MND 21st June

Introduction

Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS), is a progressive neurological disorder that affects the motor neurons responsible for controlling voluntary muscle movement. This debilitating condition leads to muscle weakness, paralysis, and eventually death due to respiratory failure. Despite extensive research, there is currently no cure for MND/ALS, and the available treatments focus on alleviating symptoms and improving patients' quality of life.

Endocannabinoids are naturally occurring compounds in the body that play a crucial role in regulating various physiological processes, including pain, mood, appetite, and immune response. Recent studies have shown that endocannabinoids may have potential in regulating MND/ALS progression. This article will discuss how endocannabinoids can influence the pathophysiology of MND/ALS without delving into the medical uses of cannabidiol (CBD).

The Endocannabinoid System and Its Role in Neuroprotection

The endocannabinoid system (ECS) is a complex cell-signalling system comprising endocannabinoids, receptors, and enzymes. The primary endocannabinoids are anandamide (AEA) and 2-arachidonoylglycerol (2-AG), which interact with cannabinoid receptors CB1 and CB2 found throughout the central and peripheral nervous systems.

The ECS plays a vital role in maintaining homeostasis within the body and has been implicated in various neuroprotective functions, such as modulating inflammation, promoting neuronal survival, and regulating synaptic transmission. These functions suggest that the ECS may have a potential role in managing neurodegenerative diseases like MND/ALS.

Endocannabinoids and MND/ALS Pathophysiology

Several studies have explored the relationship between endocannabinoids and MND/ALS pathophysiology. Key findings from these studies include:

1. Anti-inflammatory Effects: Chronic inflammation contributes to the progression of MND/ALS by causing neuronal damage and exacerbating motor neuron degeneration. Endocannabinoids, particularly through CB2 receptor activation, have been shown to possess anti-inflammatory properties, which could help reduce neuroinflammation and slow down disease progression.

2. Neuroprotection: The ECS has been implicated in promoting neuronal survival by modulating processes like autophagy (the cellular recycling system) and inhibiting apoptosis (programmed cell death). By regulating these processes, endocannabinoids may help protect motor neurons from damage and delay the onset of MND/ALS symptoms.

3. Modulation of Glial Cells: Glial cells, such as astrocytes and microglia, play essential roles in maintaining a healthy neuronal environment. However, in MND/ALS, these cells can become overactivated, leading to the release of toxic molecules that contribute to motor neuron degeneration. Endocannabinoids have been shown to modulate glial cell activity, potentially reducing their harmful effects on motor neurons.

4. Regulation of Excitotoxicity: Excitotoxicity, caused by excessive glutamate signalling, is another factor contributing to motor neuron degeneration in MND/ALS. Studies have demonstrated that endocannabinoids can modulate glutamate release and receptor activity, thereby reducing excitotoxicity and potentially slowing disease progression.

Conclusion

While more research is needed to fully understand the complex relationship between endocannabinoids and MND/ALS, current findings suggest that the endocannabinoid system may play a crucial role in regulating the pathophysiology of this devastating disease. By modulating inflammation, promoting neuronal survival, and influencing other key processes, endocannabinoids hold promise for future therapeutic interventions in MND/ALS management.

If you wish to help support and raise awareness about Motor Neuron Disease/Amyotrophic Lateral Sclerosis, you can donate here to the International Alliance of ALS/MND Associations on JustGiving.

#endocannabinoidsystem #ALS #motor neuron disease #budandtender #feelgreatagain #health #cbd

[we-nothing-but-hemp]

Buy CBD Oil Pills Online - Nothingbuthemp

If you are searching for CBD oil pills? Once CBD has been extracted from cannabis plants, it can be added to different products for consumption. CBD product retailers such as Nothing But Hemp sell CBD oil tinctures, CBD capsules, CBD gummies, and CBD hemp oil vape products. For more detail contact us Now: at [phone] or visit the website.

#hemp oil cbd capsules #cbd pure hemp oil #cbd hemp oil and als

[thcguide]

INDICA: Ein Blick auf die neue Datenbank zum Medizinalhanf

INDICA: Ein Blick auf die neue Datenbank zum Medizinalhanf #Hanf #Daten #Indica

View On WordPress

#cannabis als medizin #cannabis forschung #cannabis konsum #cbd #thc

[simplycbdnet]

Full Spectrum CBD Topical Salve Atlanta  | Full Spectrum Edibles New Orleans

We provide premium quality CBD Topicals products at an affordable price. Our full-spectrum CBD salve contains cannabinoids, terpenes, and other plants. Full-spectrum CBD Topical in Salve Atlanta is extracted from the hemp and includes several cannabinoids beyond CBD.

Read More:- https://www.simply-cbd.net/?utm_source=PDF+Submission&utm_medium=Mediatrenz&utm_campaign=Mediatrenz&utm_id=home

#Full Spectrum CBD Topical Salve Atlanta #Full Spectrum Edibles New Orleans #Full Spectrum CBD product Birmingham #Buy cbd Edibles in Daphne AL

[infozonepk]

CBD Punjab assists Al Qaim Foundation to combat Thalassemia

CBD Punjab assists Al Qaim Foundation to combat Thalassemia

Lahore Central Business District Development Authority (LCBDDA)also known as Central Business District Punjab (CBD Punjab) arranged a blood donation drive at CBD Punjab house, to assist Al Qaim Foundation in combating Thalassemia. This initiative is a testament to CBD’s corporate social responsibility agenda. Al Qaim Foundation has been doing remarkable work for the treatment of patients…

View On WordPress

#Al Qaim Foundation #CBD Punjab #Thalassemia

[hole34]

“pull yourself up by your bootstraps” is a sham.

nearly 80% of all owned american wealth is generational. prices rise while the working class’ salaries are cut, and you can’t make any profit if you’re not at the top, which you can’t do without radical exploitation of others.

I was born into a middle class life. my mom went though a lot of different jobs, most that she really liked, and we lived with my grandmother who was still working at the time. My dad was around a lot, he hadn’t become a fucking nazi yet, he had a good job and was supportive.

It slowly went downhill from there.

As my dad was treading down the conservative-to-nazi pipeline and become more paranoid, less supportive, my mom wasn’t always making enough money because her jobs became unnecessary to newer society and it was harder to find sustainable jobs, and my grandmother had to quit working because she started developing dementia. my mom worked at a UPS factory for some time before quitting because of the unworkable conditions and treatment, and her last option at that point in time was to work at the Amazon factory. she worked 7-9, one of my friends’ parents took care of me mosts nights. my mom was constantly overworked, often injured, and paid barely enough to keep us living. when covid-19 hit she was one of the first to get laid off, so all of our income came from my half-assing dad and the bare minimum from the government.

i starting developing depression around this time but we couldn’t afford or access actual mental health care, so my mom treated me with CBD oil and pot (which was still illegal in our state) she got from the only friend that continued to support our family. more and more.

i don’t remember most of 2021, it was all a blur but the one thing that will always replay in my mind is the day in november of 2021 when my mom kneeled down to me, looked me in the eyes and said

“lila, we don’t have enough money to live right now.”

i could tell things were getting weirder as time went on, but it was at this moment i realised nothing would ever be the same again. i broke down crying knowing the last years of my life at home would be spent struggling, unsupported and alone.

all the years since my mom and i have been living off of whatever money my mom can vet my father to give us, but it’s almost always a fight and almost always a no, he’s lost care for our wellbeing, and any other money has come from stuff my mom tries to sell to pawn shops. we’re on food stamps now, as fucking hard as they were to get, and we don’t really go anywhere anymore because we can’t afford it; at first it wad covid, then financially, than our home life.

my grandmother’s dementia got far worse, my mom (and myself to a lesser degree) has to take care of her full-time now, but she doesn’t get any government support for it because she obtaine power of attorney over my grama so we can still live in our house. my grandmother now is in post-awareness dementia which mentally and physically deprecating for my mom, a single mother with BPD, to take care of and it’s hell just to be in this house. fuck if you thought this was all though!

my mom was a child of 8, and she was the only one who took care of both her father, who died from ALS before my lifetime, and her crappy mother, so she still lived in her mother’s home and raised me in it. in her parents’ will however, it’s said once they both die the house will be sold and a portion of the money will be distributed to all 8 kids. that’s not enough money for my mom to live off of.

SO, my mom talked to her siblings in May of 2022 and discussed our living situation, asking for legal right to the house once their mother is gone because she’ll have no where else to live and she’s been the unpaid caretaker of both of her disabled parents since they day they needed care. but, her siblings, all of which have sustainable lives, homes and jobs, said no because they don’t care about my mom or grandma, just the shitty money they’ll inherit. there was no way of knowing when my grandma was going to pass and we wouldn’t be able to move either (my dad wouldn’t financially support it), so my mom filed a civil lawsuit on all of her siblings.

exactly two years later and we’re still in the lawsuit. nothing has changed.

aside from all the mental torture and stress the lawsuit has caused - my mom has PTSD from being abused and r*ped by the brother that’s head of the apposing side - nothing has gotten better no matter how much ANY of us do. i work now, for barely anything, and we’ve gotten a little bit more bottom-of-the-barrel government support, but it still manages to get worse. no familial support, barely any from my dad, whom of which has become mildly abusive, but can’t risk to cut ties with or else we will have absolutely no one. my mom’s sold everything valuable she had, she’s even begged for money. we don’t always have heating, we don’t always have electricity, we don’t always have food, and god fucking forbid any day we come across the police. i get by stealing energy drinks and period products, dirt money when i can, and just trying to keep my mom going and not killing herself

we can’t fucking pull ourselves up by our bootstraps, we’re already treated as barely human now being in the low class.

#capitalism #america #leftism #conservatism #low class #poverty #fuck america #fuck amazon #fuck capitalism #open your fucking eyes

[heimat-hanf-hort]

Der Einsatz von Cannabis in der medizinischen Forschung: Aktuelle Studien und Entwicklungen

Zusammenfassung:

Die Verwendung von Cannabis in der medizinischen Forschung hat in den letzten Jahren stark zugenommen, da immer mehr Studien die potenziellen therapeutischen Anwendungen von Cannabinoiden erforschen. Dieser Artikel beleuchtet die neuesten Erkenntnisse und Entwicklungen in diesem Bereich und diskutiert die Auswirkungen auf Cannabisanbauer und -konsumenten.

Einleitung:

Die medizinische Verwendung von Cannabis ist ein hochaktuelles Thema, das sowohl die Forschungsgemeinschaft als auch die Öffentlichkeit gleichermaßen beschäftigt. In diesem Artikel werfen wir einen Blick auf die aktuellen Studien und Entwicklungen im Bereich der medizinischen Forschung zu Cannabis und diskutieren deren Bedeutung für Cannabisanbauer und -konsumenten.

Die Wirkung von Cannabis in der medizinischen Forschung:

Studien haben gezeigt, dass Cannabinoide wie THC und CBD eine Vielzahl von potenziellen medizinischen Anwendungen haben können. Von der Schmerzlinderung über die Behandlung von Angstzuständen bis hin zur Unterstützung bei neurologischen Erkrankungen gibt es eine wachsende Liste von Krankheiten und Symptomen, bei denen Cannabis eine Rolle spielen könnte.

Aktuelle Studien und Entwicklungen:

Neue Forschungen untersuchen auch die Rolle von Cannabinoiden bei der Behandlung von Krebs, Epilepsie, PTSD und anderen schwerwiegenden Erkrankungen. Einige vielversprechende Studien deuten darauf hin, dass Cannabis eine wirksame Ergänzung oder Alternative zu herkömmlichen Medikamenten sein könnte.

Bedeutung für Cannabisanbauer und -konsumenten:

Für Cannabisanbauer bedeutet die zunehmende medizinische Verwendung von Cannabis ein wachsendes Interesse an spezifischen Cannabinoidprofilen und Qualitätsstandards. Für Konsumenten eröffnet sich die Möglichkeit, Cannabis nicht nur zur Freizeitnutzung, sondern auch zur Linderung von gesundheitlichen Beschwerden einzusetzen.

Expertenmeinungen:

Dr. Anna Schmidt, eine renommierte Cannabisforscherin, betont die Bedeutung von weiterer Forschung in diesem Bereich. Sie erklärt: "Die medizinische Verwendung von Cannabis hat das Potenzial, das Leben vieler Menschen zu verbessern. Es ist jedoch wichtig, dass wir weitere Studien durchführen, um die Wirksamkeit und Sicherheit von Cannabis als Medizin zu verstehen."

Real-Life-Beispiel:

Markus, ein langjähriger Cannabisanbauer, hat seine Anbaupraktiken angepasst, um den steigenden Bedarf an medizinisch wirksamen Cannabissorten zu erfüllen. Durch die Auswahl von spezifischen Genetiken und Anbaumethoden konnte er Cannabis mit einem ausgewogenen Cannabinoidprofil produzieren, das sowohl für Freizeit- als auch für medizinische Anwendungen geeignet ist.

Fazit:

Die medizinische Forschung zu Cannabis ist ein sich ständig weiterentwickelndes Gebiet, das große Chancen für die Zukunft bietet. Durch die fortlaufende Erforschung der therapeutischen Anwendungen von Cannabinoiden können wir hoffentlich neue Behandlungsmöglichkeiten für eine Vielzahl von Krankheiten und Beschwerden entdecken.

FAQs:

Ist Cannabis als Medizin legal?

In vielen Ländern ist die medizinische Verwendung von Cannabis legalisiert oder decriminalisiert. Es gibt jedoch unterschiedliche Gesetze und Vorschriften, die je nach Land oder Region variieren können.

Gibt es Nebenwirkungen bei der medizinischen Verwendung von Cannabis?

Wie bei allen Medikamenten kann die medizinische Verwendung von Cannabis Nebenwirkungen haben, darunter Müdigkeit, Schwindel und trockener Mund. Es ist wichtig, die Verwendung von Cannabis als Medizin mit einem Arzt zu besprechen.

Wie können Cannabisanbauer von der medizinischen Forschung profitieren?

Cannabisanbauer können von der medizinischen Forschung profitieren, indem sie hochwertige Cannabissorten mit spezifischen Cannabinoidprofilen anbauen, die den Bedürfnissen von medizinischen Anwendern entsprechen.

#hempflower #plantbased #smoke weed everyday #tw weed #420buds #weed life #girls who smoke weed #weedsociety #420culture #weed queen #weed intox #420daily #420deals #420girl #420life #cannagirl #cannacommunity #thc #smoke a joint #weedlife #smoke blunts #green girl #smoke ganja #stoned girls

[formulaonedirection]

hiiii, I am travelling to Singapore for the Grand Prix this year and was wondering if you had any recs of things I should do while I’m there? 🩷

helloooooo omg how fun!! I love the Singapore GP it's really fun and it's such an accessible circuit. Tbh I'm the worst person to ask because a) i love niche boring stuff b) the only things my friends and I do in Singapore is eat and hang out because that IS the national past time but let me see hmmmm

I'll just recommend some stuff that's not like. Gardens by the Bay. Sentosa. Universal Studios. The Zoo. All VERY nice places tbh and highly recommend but these are just some tiny Nadia-based reccs that you might not get from a google-able list I guess?? If you're here for a short time and you're only at the Marina Bay Sands/CBD area that's totally fine but just know that that IS the most expensive area of Singapore.

Well if you're here for a while and you're a history person I'd recommend going to the National Museum and then right down the road from there is Peranakan Museum which is tiny but fun. The National Museum is one of my favourite buildings in Singapore I just think it's so beautiful. And if you REALLY like history and museums I'd super recommend the Asian Civilisations Museum which is criminally underrated imo. If you're staying near the circuit the National Gallery is literally right there you can even pop in in the morning before the race, there's some really good local and southeast asian art in there if that's your thing.

My personal favourite place to have a wander is the Botanic Gardens. If you're a picnic person just grab some bits and bobs from Cluny Court (Plain Vanilla cupcakes are soooo good. And there's another really good bakery on the second floor) and have a nice picnic and stroll in the garden. It's pretty massive so make sure you know what you're getting into. Do NOT go on a weekend. That's crucial.

The whole Kampong Glame/Arab Street/Haji Lane is a vibe 100%. Get some boba from PlayMade, get some teh sarbat from the old man that's been serving tea there forever. There's this really good burger place like right near the mosque it's called Mahmud's Tandoor I'm obsessed with it. DO NOT let the Turkish restaurants hassle you be strong! There's some thrift stores there too but it's mostly like really good food, really nice art. The Malay Cultural Centre is like a really nice space too if you need a break.

If you want local food I'd rather you go to Maxwell's then Lau Pa Sat I actually HATE Lau Pa Sat it's theeee definition of a tourist trap. Newton Food Centre which is where they filmed that scene in Crazy Rich Asians is like fine too if you're looking for local food. If you want LOCAL LOCAL come to Al Azhar at Bukit Timah because I'm literally telling people that the steamboat fish that's there is Michellin star good. That's also a good frog porridge place down the road if you're feeling adventurous.

And my last recc is the Tiong Bahru area which is the area I used to work at. If you want cute little souvenirs or local bits and bobs there's a very cute store called Cat Socrates that I buy everything from. The Plain Vanilla there is also BEAUTIFUL it's my favourite cafe to work at. There's also like beautiful street art all along the whole area so it's just nice to walk around cause it's all just nice shophouses and art. And then there's Tiong Bahru Market which has some of the best local food. Go in the morning for this.

If you want like fancy food recs that aren't local food but are like actually good and not a scam, my personal favs are Miznon on Stanley Street, Ms Maria and Mr Singh, Five Oars Coffee Roasters on Upper East Coast. Oooh if you go to Neptune on East Coast Road you can see the pretty Peranakan buildings.

UHM YEAH! Singapore is really beautiful but VERY warm please bring sunscreen. PLEASEEEE venture outside the circuit area if you have the time because while that area is gorgeous I just think places like Haji Lane, or Tiong Bahru, or Bukit Timah, or East Coast Road are just so much more local. (Any Singaporeans reading this you know what I mean la. Nice Local. I'm not gonna recommend them to go to the coffee shop downstairs your house k)

#and don't eat rice with a fork that's really strange #I hope this is at all helpful??? if you want like more specific things/areas let me know or you can DM or whatever hahaha #ALSO BAUKE IF YOU SEE THIS I NEED TO REPLY YOUR INSTAGRAM MESSAGE BUT THESE ARE GOOD RECCS TOO #love singapore it's very safe feel free to walk the streets at 3am. 24h Fairprice Finest at 3am is the place to be #asks

[cbd-nimes-anonymseeds]

Cbd Nîmes ANONYM seeds vous propose ces huiles sublingual de CBD BIO

#cbd #anonymseeds #cbd nimes #cbd flowers #cbdcoconutoil #cannabiscommunity #cbd ales #cbd products #hemp #saveoncannabis #best cbd e liquid uk #best cbd capsules for pain relief uk #cbdproducts #delta8 #cbd capsules for sale #cbdisolate #thc #cbd capsules 1000mg #cbd capsules 50mg uk #cbd oil #magasin CBDNimes #boutiquecbdnimes #boutique bio Nimes #magasin bio îmes

[phil7281]

Discover My personal take on movies while high

My name is Phil. I’m 42 and have ALS. I am paralyzed from the neck down. Not many things make me happy or entertain me these days. I drink these water’s infused with THC or CBD, one or the other. I don’t care enough to learn the difference.  Whatever it is, this shit makes me feel goooood. I’ve noticed while I watch movies high I get a different experience. I’d like to share my personal thoughts and experiences with you. Oh, Please don’t mind the grammar 

#movies #d9 #420life #movie review #terminally ill

[we-nothing-but-hemp]

CBD Massage Oil - Nothingbuthemp

If you are searching for a CBD massage oil online in Minnesota then contact us today at Nothingbuthemp to buy this product. Pain associated with cancer itself and its treatment often occurs due to inflammation of internal organs or nerve injuries. CBD hemp oil can act as a powerful pain reliever when taken orally, by inhalation using vape pens, and even when applied topically using massage oils. For more detail call [phone] or shop for products from our website.

#cbd massage oil benefits #cbd hemp oil and als #cbd massage oil for sale

[thcguide]

Restless-Legs-Syndrom: Studie untersucht Wirksamkeit von CBD Cannabis

Restless-Legs-Syndrom: Studie untersucht Wirksamkeit von CBD Cannabis #RestlessLegs #Studie #CBD #Cannabis

Beim Restless-Legs-Syndrom zeigt das nicht psychoaktive CBD Cannabis laut einer neuen Studie keine messbare Verbesserung der Beschwerden. (Bild von Oberholster Venita auf Pixabay). Kribbeln und Zucken in den Beinen kann chronisch sein und werden und ist für Betroffene eine enorme Belastung. Eignet sich für solche Beschwerden eigentlich der Allrounder Hanf als Heilmittel? Eine neue Studie aus…

View On WordPress

#cannabis als medizin #cannabis auf rezept #cannabis forschung #cannabis studie #cbd

[simplycbdnet]

THC vs CBD for sleep aid New Orleans Tablet is meant to help enter your body system faster. The dose of CBD you use depends on several factors. Your frame weight, non-public frame chemistry, and additionally the character of your sleep problems will all affect the way CBD works.

#cbd sleep aid Atlanta #buy cbd gummies Daphne AL

[fishthegenderwitch-lurking]

This morning, after sleeping for 3 hours following my 5 hour Baldur's Gate 3 stint (which legit felt like an hour wtf TIME), secure in the Assumption* that my t-kit was in my backpack, and thus I could stay in a bed a bit longer, resulted in

Being sweaty

Being panicked

T-kit NOT in backpack oh gods where is it

Dog needs to eat, and pee

Stick dog on grass for 32 seconds

Ransack own bedroom and every conceivable place the kit could be

so sweaty, smell so bad, panic sweat is gross

shower, put clothes on that are clean

oh god I have to leave for work RIGHT NOW or suffer BEING LATE (for a boss who does not give any shape of a fuck if I'm 10minutes late)

no breakfast for me, no breakfast for my cow dog, lunch left in the fridge, no T-shot at 1pm for me

Turns out, it was in my roommate's home office, because he mistook my case for his sunglasses case (they're both black, same general shape), and it was found! Only a couple hours late for the shot but holy beans, did I deserve to use my CBD pen in the parking lot and have a great day introducing teens to Weird Al music

*This was so incorrect. So so incorrect. I'll never again make the mistake of Having Fun™ before I establish that all the pieces I need for a smooth morning are already in place.

#today #work #run around and panic #gets nothing but sweat #so gross #hella motivation to clean and sort my room though #I'll be doing that tonight lol #testosterone #tuskosterone #orc powers #hormones #trans #queer

[cruella-devegan]

Cheesecake al cioccolato - A rich and smooth chocolate layer on a crunchy hazelnut and cookie base, strawberry and whipped cream 🍰

Funghi e Tartufo

Melbourne CBD - Australia

#vegan #veganism #what vegans eat #vegan food #vegan eats #melbourne vegan #vegan melbourne #australia #melbourne #australian vegan #vegan travel #vegan australia #vegan friendly #vegan food porn #veganlife #vegans of melbourne #aussie vegan #cake #Funghi e Tartufo #vegan cake #cheesecake #vegan cheesecake #hazelnut #Melbourne cbd #vegan whipped cream #hazelnut cheesecake #strawberries #dessert #desserts #vegan dessert