Ok, idea for the PokeRus!AU...
Something happens to the timeline, and the pokerus affects only a select few. So while the villain team leaders are affected, the only one unaffected is Cyrus.
Or Red becomes hjs Mega Charizard and is terrified of hurting his cousin Blue.
Or even the chance of a fusion transformation, with Lusamine being a pheramosa and nihilego fusion, or Emmet being a galvantula with some features of gliscors and chandelures.
Just a neat thought.
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