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#NAFLD diagnosis
privatesono · 7 months
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(via Diagnosing Non-Alcoholic and Alcoholic Fatty Liver Disease Using Ultrasound Scans)
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arentiinpain · 2 years
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First post who dis
So this is where I’ll scream into the void about health issues. I have plenty.
Currently diagnosed with CPTSD, BPD, PCOS, endometriosis, hypothyroidism, NAFLD, gastritis, GERD, several vitamin deficiencies, and a temporary diagnosis of both orthostatic hypotension and some kind of autoimmune issue. The current theory is I have either dysautonomia and/or hypermobile ehlers danlos syndrome. I’ve been waiting to see a specialist for the eds idea for over a year now because there’s a single doctor in my region who specializes in it.
I’m also quite queer (genderfluid trans, they/he) and luckily on HRT (testosterone). I finally got a consultation with the single plastic surgeon in my region who does top surgery, but by they time our meeting comes around I’m not going to have health insurance that would cover it. So I’m trying to find a job with health insurance so that meeting that I’ve been waiting over a year for doesn’t end up being cancelled. Of course, I cannot personally fund this surgery because I’m unemployed in my mid-twenties in the US and am also chronically ill and disabled. I’m wanting to apply for disability in my state (at least to shove it to future employers) until I get further diagnoses to figure out why I’m fainting so often and I’m generally always in joint pain. So. That’s been fun.
So far I’ve had to leave 2 jobs (one of which was a dream job) because of my health, one of which (said dream job) I got fired for. Since I wasn’t legally disabled I couldn’t do anything about it. Yay USA.
So if listening to a man man’s ravings about being an afab disabled chronically ill queer in a red, mainly rural state in the US is your thing I’m sure I’ll be dropping occasional updates/vents/screamings. The main reason why I’m moving to tumblr to do this is because I no longer want to overshare and vent to my friends on our personal screaming chats. If you’re one of these friends, you’re free to follow me here btw.
Now I’m off to get my heating pad and an ice pack. Wahoo.
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mcatmemoranda · 2 years
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Definitions – Nonalcoholic fatty liver disease (NAFLD) refers to the presence of hepatic steatosis when no other causes for secondary hepatic fat accumulation (eg, heavy alcohol consumption (figure 1)) are present. NAFLD may progress to cirrhosis and is likely an important cause of cryptogenic cirrhosis. (See 'Definitions' above.)
NAFLD is subdivided into nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH). In NAFL, hepatic steatosis is present without evidence of significant inflammation, whereas in NASH, hepatic steatosis is associated with hepatic inflammation that may be histologically indistinguishable from alcohol-associated steatohepatitis.
●Clinical manifestations – Most patients with NAFLD are asymptomatic, although some patients with NASH may complain of fatigue, malaise, and vague right upper abdominal discomfort. Patients are more likely to come to attention because laboratory testing revealed elevated liver aminotransferases or hepatic steatosis was detected incidentally on abdominal imaging. (See 'Clinical manifestations' above.)
Patients with NAFLD may have mild or moderate elevations in the aspartate aminotransferase and alanine aminotransferase, although normal aminotransferase levels do not exclude NAFLD. (See 'Laboratory findings' above.)
Radiographic findings in patients with NAFLD include increased echogenicity on ultrasound, decreased hepatic attenuation on computed tomography, or an increased fat signal on magnetic resonance imaging. (See 'Radiographic findings' above.)
●Diagnosis – A definitive diagnosis of NAFLD requires all of the following (see 'Diagnosis' above):
•Demonstration of hepatic steatosis by imaging or biopsy
•Exclusion of significant alcohol consumption
•Exclusion of other causes of hepatic steatosis
•Absence of coexisting chronic liver disease
Radiologic findings are often sufficient to make a diagnosis of NAFLD, provided other causes of hepatic steatosis have been excluded. However, liver biopsy may be indicated if the diagnosis is not clear or to assess the degree of hepatic injury. (See 'Radiographic examinations' above and 'Role of liver biopsy' above.)
●Differential diagnosis – Other causes of hepatic steatosis include (see 'Differential diagnosis' above):
•Significant alcohol use
•Hepatitis C (particularly genotype 3)
•Wilson disease
•Lipodystrophy
•Starvation
•Parenteral nutrition
•Abetalipoproteinemia
•Medications
•Reye syndrome
•Acute fatty liver of pregnancy
•HELLP (hemolytic anemia, elevated liver enzymes, low platelet count) syndrome
•Inborn errors of metabolism
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drkumaragurubaran1 · 5 days
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Cirrhosis of the liver is a serious condition characterized by the scarring of the liver tissue. This scarring disrupts the normal functioning of the liver and can lead to various complications. Dr. Kumargurubaran, renowned for his expertise in gastroenterology and hepatology, sheds light on this critical medical issue.
What is Cirrhosis of the Liver?
Cirrhosis is the advanced stage of liver disease, where healthy liver tissue is replaced by scar tissue, affecting liver function. Over time, this scarring can impair liver function and even lead to liver failure.
Symptoms of Cirrhosis:
Early stages of cirrhosis may not exhibit noticeable symptoms. However, as the disease progresses, symptoms may include fatigue, weakness, easy bruising, swelling in the legs and abdomen, jaundice, itching, and confusion.
Causes of Cirrhosis:
Cirrhosis can be caused by various factors, including:
Alcohol Abuse: Excessive alcohol consumption over a prolonged period is a leading cause of cirrhosis. Chronic Viral Hepatitis: Hepatitis B and C infections can lead to chronic liver inflammation and cirrhosis. Nonalcoholic Fatty Liver Disease (NAFLD): Accumulation of fat in the liver, unrelated to alcohol consumption, can progress to cirrhosis. Autoimmune Hepatitis: The body's immune system attacks liver cells, leading to inflammation and cirrhosis. Genetic Disorders: Inherited liver diseases such as Wilson's disease and hemochromatosis can cause cirrhosis. Treatment Options:
While there's no cure for cirrhosis, treatment focuses on managing symptoms, slowing the progression of the disease, and preventing complications. Treatment may include lifestyle changes, medications, and in severe cases, liver transplant.
Preventing Cirrhosis:
Prevention is key in avoiding cirrhosis. This includes:
Limiting alcohol consumption Getting vaccinated against hepatitis Maintaining a healthy weight and diet Avoiding risky behaviors such as sharing needles Consulting the Best Gastroenterologist in Chennai:
For individuals in Chennai seeking expert care and guidance on cirrhosis of the liver, Dr. Kumargurubaran stands out as the top choice. With his extensive experience and commitment to patient care, Dr. Kumargurubaran offers comprehensive evaluation, diagnosis, and personalized treatment plans tailored to each patient's needs.
Conclusion:
Cirrhosis of the liver is a serious condition that requires prompt medical attention and expert care. By understanding the symptoms, causes, and treatment options, individuals can take proactive steps to manage the disease effectively. Trust Dr. Kumargurubaran, the best gastro doctor in Chennai, for expert guidance and compassionate care in dealing with cirrhosis and other gastrointestinal issues.
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The Ultimate Guide to Liver Cancer: Symptoms, Causes, and Treatment Options
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Introduction
Welcome to the ultimate guide to understanding liver cancer. In this comprehensive article, we'll delve deep into the symptoms, causes, and treatment options for this serious medical condition. Whether you're seeking information for yourself or a loved one, this guide aims to provide valuable insights to help you navigate through the complexities of liver cancer.
Understanding Liver Cancer
Liver cancer, also known as hepatic cancer, is a type of cancer that begins in the cells of the liver. The liver, a vital organ responsible for detoxification, protein synthesis, and digestion, can be affected by various types of cancer. The two primary forms of liver cancer are hepatocellular carcinoma (HCC) and cholangiocarcinoma, with HCC being the most common type.
Symptoms of Liver Cancer
Recognizing the symptoms of liver cancer is crucial for early detection and prompt treatment. Common symptoms may include:
Unexplained Weight Loss: Significant and unexplained weight loss may indicate an underlying health issue, including liver cancer.
Abdominal Pain: Persistent pain or discomfort in the abdomen, particularly in the upper right side, can be a warning sign of liver cancer.
Jaundice: Yellowing of the skin and eyes, known as jaundice, is often associated with liver diseases, including liver cancer.
Loss of Appetite: A sudden decrease in appetite or feeling full after eating small amounts could be indicative of liver cancer.
Fatigue: Persistent fatigue or weakness that doesn't improve with rest may signal liver cancer or other underlying conditions.
Causes of Liver Cancer
Several factors can contribute to the development of liver cancer. Causes may include:
Chronic Hepatitis Infections: Chronic infections with hepatitis B or hepatitis C viruses significantly increase the risk of liver cancer.
Alcohol Consumption: Excessive and prolonged alcohol consumption can lead to liver damage and increase the likelihood of developing liver cancer.
Non-Alcoholic Fatty Liver Disease (NAFLD): NAFLD, a condition characterized by the accumulation of fat in the liver, can progress to liver cancer in some cases.
Liver Cirrhosis: Cirrhosis, a late-stage scarring of the liver, is a significant risk factor for liver cancer.
Family History: A family history of liver cancer or certain genetic conditions can predispose individuals to the disease.
Diagnosis and Treatment Options
Diagnosing liver cancer typically involves a combination of medical history review, physical examination, imaging tests, and biopsy. Once diagnosed, treatment options may vary depending on the stage of the cancer and the patient's overall health. Treatment options may include:
Surgery: Surgical resection, where the tumor is removed along with a portion of healthy liver tissue, is often recommended for early-stage liver cancer.
Liver Transplant: In cases where the cancer has not spread beyond the liver and the patient meets specific criteria, a liver transplant may be considered.
Chemotherapy: Chemotherapy involves the use of drugs to destroy cancer cells and may be used before or after surgery, or in cases where surgery is not an option.
Radiation Therapy: Radiation therapy uses high-energy beams to target and kill cancer cells and may be used as a standalone treatment or in combination with other therapies.
Targeted Therapy: Targeted therapy drugs are designed to attack specific abnormalities within cancer cells and disrupt their growth and spread.
Conclusion
In conclusion, liver cancer is a serious condition that requires prompt diagnosis and comprehensive treatment. By understanding the symptoms, causes, and treatment options outlined in this guide, individuals can take proactive steps towards managing and treating liver cancer effectively. Remember, early detection and intervention play a crucial role in improving outcomes and quality of life for those affected by this disease. If you or a loved one experience any concerning symptoms associated with liver cancer, don't hesitate to consult with a healthcare professional for further evaluation and guidance. Stay informed, stay proactive, and prioritize your health and well-being.
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vimdrugs · 12 days
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Living with gastroparesis can be a challenging journey for patients, extending well beyond the realm of mealtime. This debilitating digestive disorder affects the stomach's ability to empty properly, leading to a host of physical and emotional symptoms. At VIM Drugs, we understand the emotional impact of gastroparesis and the importance of offering comprehensive support options to patients.
In this article, we explore the emotional toll that gastroparesis can take on those diagnosed with the condition. From feelings of frustration and isolation to anxiety and depression, we delve into the various emotional challenges that patients face on a daily basis.
What is Gastroparesis?
Gastroparesis is a chronic condition that affects the normal movement of the muscles in the stomach, leading to delayed emptying. This can cause a range of symptoms, including bloating, nausea, vomiting, and feelings of fullness. While the physical symptoms are challenging enough to deal with, the emotional impact of gastroparesis should not be underestimated.
Living with gastroparesis often means facing daily struggles and limitations that can take a toll on one's emotional well-being. The inability to eat a normal meal, constant discomfort, and uncertainty about when symptoms will flare up can lead to frustration, anxiety, and even depression. It's crucial to acknowledge and address these emotions to ensure a holistic approach to managing gastroparesis.Challenges FacedEffects on PatientsInability to eat normal mealsFrustration, anxietyConstant discomfortIsolationUncertainty of symptom flare-upsDepression
Coping with the Physical and Emotional Challenges
Coping with gastroparesis involves not only managing the physical symptoms but also addressing the emotional challenges that come along with the condition. It's important to recognize that you are not alone in this journey and that there are support options available to help you navigate the ups and downs.
One of the first steps in coping with the emotional challenges of gastroparesis is to educate yourself about the condition. Understanding the causes, symptoms, and treatment options can empower you to take control of your health and make informed decisions. Knowledge can also help alleviate some of the anxiety and uncertainty that often accompany living with a chronic condition.
Support Options for Gastroparesis Patients
While the emotional impact of gastroparesis can be overwhelming, there are support options available to help you cope and find solace in a community that understands. Here are some resources that can make a difference:
Online Support Communities and Forums
The internet has made it easier than ever to connect with others who are going through similar experiences. Online support communities and forums provide a platform for gastroparesis patients to share their stories, ask questions, and offer support to one another. 
These virtual communities can be a valuable source of encouragement and understanding, allowing you to connect with people who truly understand what you're going through.
Support Groups and Counseling Services
In addition to online communities, there are also support groups and counseling services specifically tailored for gastroparesis patients. These groups provide a safe space to share your thoughts and feelings, seek advice, and receive emotional support from others who can relate to your struggles. 
Counseling services, whether in-person or online, can also be beneficial in helping you navigate the emotional challenges of living with gastroparesis.
The Role of Family and Friends in Providing Emotional Support
While professional support is important, the role of family and friends should not be overlooked. Loved ones can play a crucial role in providing emotional support to gastroparesis patients. They can offer a listening ear, lend a helping hand, and provide the understanding and encouragement needed to navigate the emotional ups and downs. 
Open communication and education about the condition can help family and friends better understand the challenges you face and enable them to offer the support you need.
Tips for Caregivers of Gastroparesis Patients
Gastroparesis not only affects the patients themselves but also their caregivers. Taking care of someone with gastroparesis can be demanding both physically and emotionally. As a caregiver, it's important to prioritize your own well-being and seek support when needed. 
Joining caregiver support groups, seeking respite care, and practicing self-care are essential in ensuring that you can provide the best possible support to your loved one.
The Importance of Self-Care for Gastroparesis Patients
Self-care is crucial for gastroparesis patients to manage both the physical and emotional aspects of the condition. Taking care of yourself mentally, emotionally, and physically can help alleviate stress and improve overall well-being. This may include practicing relaxation techniques, engaging in activities that bring joy, seeking professional help when needed, and following a well-balanced diet that suits your specific needs.
NAFLD causes:
Diet and Lifestyle
Too Many Calories: If you consistently consume more calories than your body needs, especially from sugary drinks and unhealthy fats, your liver can become overloaded. It struggles to process and break down these nutrients efficiently, which can contribute to NAFLD.
Processed Food Overload: Foods packed with refined carbs, trans fats, and added sugars can trigger inflammation and stress in your liver. This can worsen symptoms of NAFLD.
Metabolic Connections
Several other health conditions are linked to NAFLD and can make it worse. These include:
Type 2 Diabetes: When your body struggles to use insulin effectively (insulin resistance), a key feature of type 2 diabetes, it raises your risk of NAFLD. These conditions often occur together, accelerating liver damage.
Metabolic Syndrome: This is a combination of several factors, including obesity, high blood pressure, high blood sugar, and unhealthy cholesterol levels. Having metabolic syndrome significantly increases your chances of developing NAFLD and serious complications.
Unbalanced Cholesterol: Abnormal cholesterol levels, especially high triglycerides and low HDL ("good") cholesterol, contribute to fat buildup and inflammation in the liver, worsening NAFLD.
Genes and Heredity
While lifestyle choices are important, your genes can also influence your risk of NAFLD. Here's how:
Family History: If NAFLD or related conditions run in your family, you may be more susceptible due to your genes.
Genetic Variations: Scientists have identified specific gene variations that increase the risk of NAFLD development and progression. These genes can affect how your body manages fat, inflammation, and insulin sensitivity, all of which play a role in NAFLD.
Can I prevent NAFLD?
Absolutely! There are steps you can take to significantly reduce your risk of developing NAFLD. Here's how a healthy lifestyle can help:
Get Moving Regularly: Aim for consistent physical activity.
Eat a Balanced Diet: Focus on nutritious foods and watch your portion sizes.
Maintain a Healthy Weight: Losing weight if needed and keeping it off can be very beneficial.
Also Read: Essential Cybersecurity Best Practices for Pharmacies in the US | VIM Drugs
Conclusion
Living with gastroparesis can be challenging, but it's important to remember that you are not alone. Understanding the emotional impact of the condition and seeking support from various resources can make a significant difference in your journey. 
Whether it's through online communities, support groups, counseling services, or the support of loved ones, finding solace in a community that understands can provide the understanding, encouragement, and resilience needed to navigate the ups and downs of living with gastroparesis.
At VIM Drugs, we are committed to providing not only effective treatment options but also support beyond the medication. We understand the unique struggles faced by gastroparesis patients and believe in fostering connection and empowerment. Together, we can overcome the emotional challenges of gastroparesis and find hope and support in the journey towards improved quality of life.
» » Reach out to us for any query: Contact us
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pacehospitalshyd · 13 days
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PACE Hospitals: Best Center for Advanced Hepatology Care in Hyderabad, India
Liver disease can be a complex and concerning issue. At PACE Hospitals, we understand the importance of early diagnosis, effective treatment, and compassionate care for patients with liver problems. Our dedicated team of hepatologists offers the latest advancements in hepatology to ensure the best possible outcomes for our patients.
A certified experienced medical hepatologist doctors in Hyderabad, with a good patient satisfaction feedback, could be the best hepatologist doctors. Hepatologist doctor at PACE hospitals are internationally and nationally accredits with deep exposure in assessing, diagnosing and treating several kinds of hepatic diseases with a high patient satisfaction rate.
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What is Hepatology?
Hepatology is a branch of medicine specializing in the diagnosis, treatment, and management of diseases affecting the liver, gallbladder, biliary system, and pancreas.
Our Expertise in Hepatology
PACE Hospitals boasts a team of highly qualified  hepatologists with extensive experience in treating a wide range of liver conditions, including:
Viral Hepatitis (A, B, C)
Fatty Liver Disease (Nonalcoholic Fatty Liver Disease - NAFLD)
 Autoimmune Hepatitis
 Cirrhosis
 Cholangitis (bile duct inflammation)
Pancreatitis
Department of Hepatology (Liver Care) and Pancreatology:
Dr. Govind Verma :
MD, DM (Gastroenterology)
Interventional Gastroenterologist, Transplant Hepatologist, Pancreatologist and Endosonologist
23 years of experience
Dr. Govind Verma, is a senior Interventional Gastroenterologist, Hepatologist and Endosonologist. He has a special interest in the treatment of Liver disorders: like Hepatitis B and C, cirrhosis of liver, Liver cancer (HCC); Pancreatic disorders: Pancreatitis, Pancreatic tumour (Cancer); Inflammatory bowel disease: like ulcerative colitis and crohns disease; Oesophageal and anorectal motility diseases: Like Achalasia cardia, Diffuse oesophageal spasm, Hirschsprungs; Functional bowel diseases.
Dr. M Sudhir:
MBBS, MD (Internal Medicine), DNB(Internal Medicine), DNB(Gastroenterology), FICP
Senior Gastroenterologist and Hepatologist
35+ years of experience
Dr. M Sudhir, is a Senior Gastroenterologist, having 35+ years of experience. He was award TWO GOLD MEDALS in MBBS and TWO GOLD MEDALS in MD (Internal Medicine). He has a special interest in the treatment of Inflammatory bowel diseases such as Ulcerative colitis and Crohn's disease, GI motility disorders such as achalasia cardia, Hirschsprungs, Diffuse oesophageal spasm, Pancreatico-biliary disorders such as chronic pancreatitis, CBD stones, Gall Stones, Malignancies, functional bowel disorders such as Irritable bowel syndrome and Liver diseases and their conditaions.
He has extensive experience in both diagnostic and therapeutic UGI endoscopy, colonoscopy and ERCP. He has special interest in advance and therapeutic endoscopic procedures like third space endoscopy, POEM, Endoscopic sleeve Gastroplasty (ESG) and Endoscopic ultrasound.
Dr. R Venkatesh Reddy:
MBBS, MD (Internal Medicine), DM (Medical Gastroenterology)Consultant Gastroenterologist and Hepatologist
Dr. R Venkatesh Reddy has extensive experience in the field of Gastroenterology, Hepatology and Endoscopy. He is expert in treating GI motility disorders, all types of Liver diseases, Acute and Chronic pancreatitis, Common bile duct stone (choledocholithiasis), Cholangitis, Inflammatory bowel diseases, Lemmel syndrome, Gastric cancer, Irritable bowel syndrome etc.
He specialises in performing ERCP, Diagnostic EUS and EUS-guided therapeutic interventions, Endoscopic pancreatic and bile duct stenting, Spiral enteroscopy, Oesophageal manometry, Upper and Lower GI Endoscopies, Endoscopic variceal ligation, Polypectomy, Argan plasma coagulation, Narrow-band imaging, Oesophageal bougie dilation, Colonic stricture dilation, Achalasia balloon dilation, Ano-rectal manometry, Spyglass cholangioscopy etc.
Advanced Technology and Treatment Options:
We are equipped with state-of-the-art technology for accurate diagnosis and advanced treatment modalities for liver disorders.  Our hepatologists utilize:
Non-invasive diagnostic tools like FibroScan and liver elastography
    Advanced endoscopic procedures (ERCP)
    Minimally invasive surgical techniques (laparoscopy)
    Liver transplant services (in collaboration with our Kidney and Liver Transplant Centre)
A Holistic Approach to Liver Care:
We believe in a comprehensive approach to hepatology care.  Our team works closely with patients to develop individualized treatment plans that address not just the disease but also the patient's overall well-being.  This may include:
    Dietary and lifestyle modifications
    Medication management
    Education and support groups
Why Choose PACE Hospitals for Hepatology Care?
Experienced and Renowned Team: Our hepatologists are leaders in their field, with a proven track record of success.
    Advanced Technology: We utilize cutting-edge technology for diagnosis and treatment.
    Comprehensive Care: We offer a holistic approach, addressing all aspects of your liver health.
    Patient-Centered Focus: We prioritize clear communication, respect, and empathy for all our patients.
Schedule a Consultation Today:
PACE Hospitals is a multi-super speciality hospital  in Hyderabad catering to a wide range of treatments with the help of top hepatologist in Hyderabad who are nationally and globally awarded, highly skilled and experienced in their respective departments and accustomed to treating patients based on evidence and the latest approaches and procedures.
If you are experiencing symptoms of liver disease or have concerns about your liver health, don't hesitate to contact PACE Hospitals.  Schedule a consultation with one of our hepatologists to discuss your individual needs and get on the path to optimal liver health.
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drmsskeerthi · 16 days
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Liver Cancer
Are you looking for the best liver cancer surgeon in Hyderabad? Dr. M.S.S. Keerthi is an excellent choice for liver cancer treatment by providing topnotch care for patients, she has treated more than 10000+ cancer patients and currently, Dr. M.S.S Keerthi is working as Sr. Consultant Surgical Oncologist and laparoscopic and robotic Surgeon at Tulasi Hospital, and Evoke Clinic at Securandarbad, Telangana.
With her exceptional expertise, patient-centric philosophy, and steadfast dedication to excellence, Dr. M.S. S Keerthi has firmly established herself as a leading liver cancer surgeon . Whether you seek advanced treatment for liver cancer or personalized care for related concerns, Dr. M.S. S Keerthi offers unparalleled services customized to your individual needs.
What is liver cancer ?
Liver cancer, also known as hepatocellular carcinoma (HCC), is a malignancy that originates in the liver cells. It is among the most prevalent cancers worldwide and a significant cause of cancer-related mortality. Liver cancer can manifest in various forms, including primary liver cancer, which originates within the liver, and secondary liver cancer, which spreads to the liver from other parts of the body.
Stages of the Liver Cancer:
Dr. M.S.S. Keerthi explains the stages of liver cancer and how far spread of cancer occurs:
Stage 0: Cancer is localized, hasn’t invaded deeper tissues.
Stage I: A single tumor up to 2 cm in diameter, confined to the liver.
Stage II: Single tumor larger than 2 cm or multiple tumors, none larger than 5 cm, still confined to the liver.
Stage III: Tumor( s) invade near blood vessels or organs but have not spread distantly.
Stage IV: spread to near lymph bumps or distant organs.
Causes of liver cancer:
Best cancer specialist in Hyderabad ,Dr MSS Keerthi says liver cancer can be caused by various factors that damage the liver cells and disrupt normal cell growth processes. Some of the primary causes and contributing factors to liver cancer include:
Chronic Liver Diseases, like Cirrhosis: One of the leading causes of liver cancer is chronic liver disease, especially cirrhosis. Cirrhosis is often the result of long-term damage to the liver caused by conditions like excessive alcohol consumption, hepatitis B or C infections, or non-alcoholic fatty liver disease (NAFLD).
Hepatitis B or C Infections: Chronic infections with hepatitis B or C viruses can significantly increase the risk of developing liver cancer over time.
Excessive Alcohol Consumption: Prolonged and excessive alcohol consumption can lead to liver damage and increase the risk of liver cancer.
Obesity: Obesity is a known risk factor for liver cancer, as it can lead to the accumulation of fat in the liver, inflammation, and scarring.
Family History: Individuals with a family history of liver cancer may be at a higher risk, as there can be genetic predispositions to the disease.
Symptoms of liver cancer:
The symptoms of liver cancer can vary and may not appear in the early stages. Common symptoms include:
Abdominal Pain or Discomfort: Pain or a feeling of fullness in the upper abdomen is a common symptom of liver cancer.
Jaundice: Yellowing of the skin and eyes (jaundice) can occur when the cancer affects the liver’s ability to process bilirubin.
Unexplained Weight Loss: Significant and unexplained weight loss can be a sign of liver cancer.
Fatigue: A general feeling of weakness and fatigue can result from the cancer’s impact on the liver’s functions.
Diagnosis and Treatment:
Diagnosis: Liver cancer is typically diagnosed through a combination of tests, including imaging tests , blood tests, and sometimes a liver biopsy to confirm the presence of cancer.
Blood tests: Blood Tests may be done to measure situations of certain substances in the blood that can indicate liver function and the presence of liver cancer, similar as alpha- fetoprotein( AFP) and liver function tests( LFTs).
Biopsy: If imaging tests suggest the presence of liver cancer, a biopsy may be performed to confirm the diagnosis. During a biopsy, a small sample of liver tissue is removed and examined under a microscope by a pathologist to look for cancer cells.
Imaging tests: Imaging tests for liver cancer include ultrasound, CT scans, MRI scans, and PET scans. These tests help visualize the liver and discover abnormalities. Ultrasound uses sound waves, CT scans combine X-rays for detailed images, MRI scans use glamorous fields and radio waves, and PET scans highlight cancerous areas using a radioactive tracer.
Treatment: Treatment options provided by Dr. M.S.S. Keerthi for liver cancer depend on the stage of the disease and the patient’s overall health. They can include:
Surgery: Surgical options may involve removing the tumor (partial hepatectomy) or a liver transplant in cases where the cancer is confined to the liver and the patient is a suitable candidate.
Chemotherapy: Chemotherapy drugs can be used to target and kill cancer cells.
Targeted Therapy: Targeted therapy drugs focus on specific molecules involved in the growth and spread of cancer cells.
Radiation Therapy: High-energy X-rays are used to kill cancer cells or slow their growth.
Ablation and Embolization: Procedures like radiofrequency ablation or transarterial chemoembolization can be used to treat liver tumors.
Prevention of Liver cancer:
According to the best liver cancer surgeon in Hyderabad Dr. M.S.S Keerthi, to prevent liver cancer, individuals can take several steps to reduce their risk:
Getting vaccinated against hepatitis B.
Avoiding needle sharing.
Limiting alcohol intake.
Maintaining a healthy weight.
Eating a nutritious diet.
Managing chronic liver diseases.
Why Choose Dr. MSS Keerthi for Liver Cancer Treatment in Hyderabad:
Expert Oncologist: Dr.M.S.S. Keerthi is described as an expert surgical oncologist with more than 15+ years of experience in performing various cancer surgeries. Having specialized in Surgical Oncology from the Cancer Institute, she’s likely to retain a deep understanding of liver cancer and its treatment.
State-of-the-Art Facility: The citation of a state- of- the- art facility suggests that the medical structure where Dr. M.S.S. Keerthi practices are equipped with improved technologies and ultra modern amenities. And other installations like wheelchair accessible, cleaned toilets and proper consulting rooms.
Clinic Location: Dr. M.S.S. Keerthi practices at Tulasi Hospital and Evoke Clinic in Secunderabad, Telangana. 
Diagnostic Services under one Roof: The availability of diagnostic services in the same facility can streamline the individual process for patients. Having all necessary experiments and services like stomach cancer treatment, lung cancer treatment, & targeted therapy in one position may conduct to a more effective and coordinated path to diagnosis and treatment planning.
Experienced & Trained Staff: Dr. M.S.S. Keerthi is supported by experienced and trained staff, which implies a collaborative and well-coordinated approach to patient care.
Personal Care, Every Time: Dr. M.S.S. Keerthi is noted for her compassionate and tailored approach to patient care, which includes listening to patients’ concerns and working closely with them to establish personalized treatment programs.
Book An Appointment:-
Dr. M.S.S Keerthi  provides the best treatment for various cancer diseases in Secunderabad and Hyderabad. For more information about our comprehensive treatment options, or to request an appointment with the best surgical oncologist in Secunderabad, Hyderabad call +91 9490808080 or Click on Book Appointment for online booking.
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phoenix-ultrasound · 28 days
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delveinsight12 · 30 days
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Understanding the Dynamics of the Siderosis Market: Drivers, Barriers, and Future Outlook
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Siderosis is a medical condition characterized by the accumulation of iron in the body, particularly in tissues and organs. This condition typically occurs as a result of prolonged exposure to iron-containing substances, such as iron dust or particles, which can enter the body through inhalation or ingestion.
Siderosis can affect various organs and tissues, including the lungs, liver, spleen, and bone marrow. In the lungs, the accumulation of iron particles can lead to pulmonary siderosis, which may cause respiratory symptoms such as coughing, shortness of breath, and chest pain. In severe cases, pulmonary siderosis can result in lung fibrosis and impairment of lung function.
Excessive iron accumulation in the liver can cause hepatic siderosis, which may lead to liver damage and dysfunction. Symptoms of hepatic siderosis can include abdominal pain, jaundice, fatigue, and swelling of the abdomen.
Diagnosis of siderosis typically involves a thorough medical history, physical examination, and laboratory tests to assess iron levels in the blood and tissues. Imaging studies, such as chest X-rays or MRI scans, may also be performed to evaluate the extent of iron accumulation in affected organs.
Siderosis treatment depends on the underlying cause and severity of the condition. In cases of occupational exposure to iron-containing substances, prevention measures such as wearing protective equipment and minimizing exposure to iron dust are essential. Treatment may also involve iron chelation therapy, which aims to remove excess iron from the body and prevent further tissue damage.
Overall, siderosis is a condition characterized by the abnormal accumulation of iron in the body, which can lead to various health problems depending on the organs affected and the extent of iron overload. Early diagnosis and appropriate management are crucial for preventing complications and improving outcomes in individuals with siderosis.
Siderosis Market Drivers
Increasing Prevalence of Iron Overload Disorders: The rising prevalence of conditions associated with iron overload, such as hereditary hemochromatosis, thalassemia, and transfusion-dependent anemias, drives the demand for siderosis treatments. As awareness of these disorders grows and diagnostic capabilities improve, more individuals are being diagnosed with iron overload, thereby expanding the market.
Advancements in Diagnostic Technologies: Technological advancements in diagnostic tools, such as serum ferritin testing, genetic testing, and imaging modalities like MRI, facilitate early detection and monitoring of iron overload conditions. Improved diagnostic accuracy and accessibility contribute to the identification of more patients with siderosis, driving demand for treatments and management strategies.
Rising Demand for Iron Chelation Therapies: Iron chelation therapies play a crucial role in managing iron overload by binding excess iron and facilitating its excretion from the body. With increasing recognition of the importance of controlling iron levels in patients with siderosis, there is a growing demand for iron chelators, both oral and intravenous, as well as newer, more effective formulations with improved safety profiles.
Expanding Patient Pool: The aging population and the growing prevalence of chronic diseases associated with iron overload contribute to an expanding patient pool for siderosis treatments. Conditions such as non-alcoholic fatty liver disease (NAFLD), chronic liver disease, and chronic kidney disease (CKD) are increasingly recognized as risk factors for iron overload, further driving the demand for siderosis management strategies.
Research and Development Initiatives: Ongoing research efforts aimed at developing novel therapies for siderosis, including iron chelators with enhanced efficacy and reduced side effects, drive innovation in the market. Collaborations between pharmaceutical companies, academic institutions, and research organizations contribute to the development of new treatment options, expanding the therapeutic armamentarium for siderosis.
Regulatory Support: Regulatory agencies play a crucial role in facilitating the development and approval of siderosis treatments. Expedited pathways for orphan drug designation and accelerated approval help streamline the regulatory process for promising therapies, encouraging investment in research and development for siderosis management.
Increasing Healthcare Expenditure: Rising healthcare expenditure globally, particularly in developed regions, supports greater access to siderosis diagnostics and treatments. Healthcare policies and reimbursement frameworks that cover the cost of siderosis management contribute to improved patient access and affordability of treatments, driving market growth.
Siderosis Market Barriers
Underdiagnosis and Misdiagnosis: Siderosis, particularly hereditary forms such as hereditary hemochromatosis, is often underdiagnosed or misdiagnosed due to its nonspecific symptoms and resemblance to other conditions. This can lead to delays in treatment initiation and missed opportunities for early intervention.
Limited Awareness among Healthcare Providers: Many healthcare providers may not be adequately trained to recognize the signs and symptoms of siderosis, leading to diagnostic errors or delays. Lack of awareness about the condition can also result in suboptimal management and treatment strategies.
Complex Diagnostic Process: Diagnosing siderosis typically requires a combination of clinical evaluation, laboratory tests (such as serum ferritin levels and transferrin saturation), and genetic testing. The complexity and cost of these diagnostic procedures can act as barriers to timely diagnosis and treatment initiation.
High Cost of Treatment: Iron chelation therapy, the primary treatment for siderosis, can be expensive, particularly for patients without adequate insurance coverage or access to healthcare services. The high cost of treatment may limit access to care and adherence to prescribed therapy regimens.
Adverse Effects of Treatment: Iron chelation therapy is associated with potential side effects and risks, including gastrointestinal symptoms, allergic reactions, and renal toxicity. Concerns about adverse effects may deter some patients from initiating or continuing treatment, impacting treatment outcomes.
Limited Treatment Options: While iron chelation therapy is effective in managing iron overload in many patients, there are limited alternative treatment options available for those who do not respond adequately or experience intolerable side effects. The lack of diverse treatment modalities can pose challenges for patients and healthcare providers seeking optimal management strategies.
Regulatory Challenges: The development and approval of new siderosis treatments can be hindered by regulatory hurdles, including stringent requirements for safety and efficacy data. Delays in regulatory approval processes may limit the availability of innovative therapies and slow down market growth.
Stigma and Psychosocial Impact: Siderosis, particularly hereditary forms, may be associated with stigma, genetic testing concerns, and psychosocial challenges related to chronic illness. Stigma and psychosocial factors can affect patients' willingness to seek diagnosis and treatment, as well as their overall well-being and quality of life.
Future Siderosis Market Analysis
The Siderosis market is poised for significant growth in the coming years, driven by ongoing research, technological advancements, and evolving treatment paradigms. Key trends and developments shaping the future of the market include:
Advancements in Diagnostic Technologies: Continued advancements in diagnostic technologies, such as genetic testing and imaging modalities, are expected to improve the early detection and monitoring of siderosis. Enhanced diagnostic accuracy and accessibility may lead to more timely diagnosis and treatment initiation, driving market growth.
Rising Awareness and Education: Increasing awareness among healthcare professionals and the general public about siderosis and its associated risks may lead to higher rates of diagnosis and treatment. Education campaigns and advocacy efforts aimed at raising awareness about iron overload disorders could contribute to market expansion.
Focus on Personalized Medicine: The emergence of personalized medicine approaches, including genetic testing and precision therapies, may revolutionize siderosis treatment. Tailoring treatment strategies based on individual patient characteristics and genetic profiles could optimize therapeutic outcomes and minimize side effects, driving demand for personalized therapies.
Development of Novel Therapies: Ongoing research efforts are likely to lead to the development of novel therapies for siderosis, including next-generation iron chelators, targeted therapies, and gene-based treatments. The introduction of innovative therapies with improved efficacy and safety profiles could significantly impact the siderosis market landscape.
Regulatory Support and Market Access: Streamlined regulatory pathways and favorable reimbursement policies may facilitate the development and commercialization of new siderosis treatments. Regulatory support and market access initiatives could accelerate the availability of innovative therapies and expand treatment options for patients.
Global Expansion and Market Penetration: The siderosis market may witness expansion into new geographic regions, driven by increasing disease awareness, improved healthcare infrastructure, and growing demand for effective treatments. Market penetration into emerging economies could present opportunities for market growth and expansion.
Patient-Centric Care and Support Services: There is likely to be a growing focus on patient-centric care and support services for individuals affected by siderosis. Comprehensive care models that address the holistic needs of patients, including psychosocial support, adherence management, and access to resources, may become increasingly prevalent.
Technological Innovations and Digital Health Solutions: Technological innovations, such as telemedicine, remote monitoring, and digital health platforms, could play a significant role in siderosis management. These solutions may improve patient engagement, facilitate remote consultations, and enhance disease monitoring and management, contributing to improved patient outcomes.
Evolving Siderosis Treatment Outlook
The treatment landscape for Siderosis is evolving rapidly, with a shift towards targeted therapies and personalized approaches. Key developments shaping the evolving treatment outlook include:
Early Diagnosis and Screening: There's a growing emphasis on early detection and screening for iron overload disorders, such as hereditary hemochromatosis and transfusion-dependent anemias. Improved understanding of genetic predisposition and more accessible diagnostic tests allow for earlier identification of at-risk individuals, enabling timely intervention to prevent complications.
Personalized Treatment Approaches: The evolving treatment landscape for siderosis emphasizes personalized approaches tailored to individual patient characteristics. Genetic testing enables identification of specific genetic mutations associated with iron overload disorders, guiding treatment decisions and optimizing therapy efficacy.
Iron Chelation Therapy Advancements: Iron chelation therapy remains a cornerstone of treatment for siderosis, aiming to reduce iron burden and prevent organ damage. Advancements in chelation agents, including novel oral formulations and targeted therapies, offer improved efficacy, tolerability, and patient convenience compared to traditional therapies.
Combination Therapies: Combination therapies involving multiple chelation agents or adjunctive treatments are being explored to enhance iron removal and address specific aspects of iron overload pathology. Combinations of chelators with antioxidants or anti-fibrotic agents, for example, may offer synergistic benefits in managing siderosis-related complications.
Gene Therapy and Gene Editing: Emerging gene therapy and gene editing technologies hold promise for treating hereditary forms of iron overload disorders at the genetic level. Strategies aimed at correcting or modulating the underlying genetic defects responsible for iron accumulation offer potential long-term therapeutic benefits, though they are still in early stages of development.
Improved Monitoring and Management: Advances in monitoring techniques, such as non-invasive imaging modalities and biomarker assays, enable more accurate assessment of iron burden and treatment response. Real-time monitoring facilitates proactive management of siderosis, allowing for timely adjustments to treatment regimens and optimization of patient outcomes.
Patient-Centered Care: There's a growing recognition of the importance of patient-centered care in siderosis management, addressing not only the physical aspects but also the psychosocial and quality-of-life considerations. Comprehensive care models encompassing patient education, psychosocial support, and lifestyle interventions are integral to optimizing treatment outcomes and patient well-being.
Clinical Research and Therapeutic Innovation: Ongoing clinical research efforts continue to drive therapeutic innovation in siderosis treatment. Investigational therapies targeting novel pathways involved in iron metabolism, as well as repurposed agents with potential iron-chelating properties, hold promise for expanding the therapeutic armamentarium and improving treatment options for patients with iron overload disorders.
Role of Companies in the Siderosis Market
In the Siderosis market, companies such as Novartis Pharmaceuticals Corporation, Apotex, Chiesi Group, Luitpold Pharmaceuticals, ApoPharma Inc., Teva Pharmaceutical Industries Ltd., Galen Limited, Cipla,  and others play a pivotal role in driving innovation, research, development, and the provision of treatments and therapies for individuals suffering from this chronic inflammatory skin condition. These companies encompass pharmaceutical giants, biotechnology firms, medical device manufacturers, and healthcare service providers, each contributing uniquely to the advancement of Siderosis management. Pharmaceutical companies lead the charge in developing novel drugs, ranging from topical corticosteroids to biologics targeting specific immune pathways implicated in Siderosis pathogenesis. 
Siderosis Market Outlook - Key Conclusion and Analysis
The Siderosis market is undergoing a transformative period, driven by advances in research, innovation in therapeutic approaches, and shifting treatment paradigms. While significant progress has been made in improving outcomes for patients with Siderosis, several barriers continue to challenge the market's expansion, including high treatment costs, safety concerns, and regulatory hurdles. Looking ahead, personalized medicine, novel therapeutic targets, and digital health solutions are poised to shape the future of Siderosis management, offering new hope for patients and caregivers alike. Efforts to address these challenges and capitalize on emerging opportunities will be critical in advancing the field and ultimately improving the lives of individuals living with Siderosis.
Get a more detailed overview, at: Siderosis Market Outlook and Forecast
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privatesono · 26 days
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bhushans · 1 month
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Beyond Diagnosis: Exploring Global hepatic markers Market
The global hepatic markers market is poised for significant growth in the coming years, with a projected valuation of US$4.2 billion by 2033, according to a recent market study by Future Market Insights (FMI). This substantial growth, reflecting a Compound Annual Growth Rate (CAGR) of 6.2%, underscores the critical role hepatic markers play in the fight against liver disease worldwide.
Early Detection, Personalized Care: Hepatic Markers Leading the Charge
Several key factors are propelling this exciting market expansion:
Rising Prevalence of Liver Disease: Liver diseases such as viral hepatitis, alcoholic liver disease, and Non-alcoholic Fatty Liver Disease (NAFLD) are on the rise globally. This growing burden fuels the demand for effective diagnostic tools like hepatic markers for early detection and disease monitoring.
Non-invasive Diagnostics Gain Favor: Patients increasingly prefer non-invasive methods like blood tests and imaging techniques over traditional, invasive liver biopsies. Hepatic markers offer a convenient, safe, and accurate alternative for liver health assessment.
Advancements in Technology: Continuous advancements in diagnostic technologies lead to the development of more precise and reliable hepatic markers.
Personalized Medicine Revolution: The growing emphasis on personalized medicine necessitates tailored treatment plans. Hepatic markers empower healthcare professionals to develop individualized treatment strategies based on a patient's specific needs.
Download Our Sample Report! https://www.futuremarketinsights.com/reports/sample/rep-gb-17659
A Market on the Rise: Factors Driving Growth
The hepatic markers market has witnessed significant growth in recent years, driven by several key trends:
Growing Demand for Non-invasive Tools: As mentioned earlier, the preference for non-invasive diagnostic methods is a major driver.
Focus on Early Detection & Prevention: Early diagnosis is crucial for successful liver disease management. Hepatic markers play a vital role in identifying the disease at its earliest stages.
Rising Healthcare Awareness: Increased public awareness about liver health is leading to more proactive testing and diagnosis.
Key Takeaways From The Hepatic Markers Market:
The hepatic markers industry in the United States is predicted to reach US$ 1.1 billion by 2033, increasing at a 3.7% CAGR.
The hepatic markers industry in the United Kingdom is estimated to reach a market value of US$ 180.2 million, expanding at a CAGR of 3.8% by 2033.
During the forecast period, the hepatic markers industry in China is expected to reach a market value of US$ 241.2 million, securing a 6.4% CAGR.
The hepatic markers industry in Japan is predicted to reach US$ 177.4 million by 2033, increasing at a 6.2% CAGR.
South Korea's hepatic markers industry is set to rise at a 6.0% CAGR during the forecast period.
With a CAGR of 5.6% from 2023 to 2033, Aspartate transaminase (AST) is expected to dominate the hepatic markers industry.
With a CAGR of 5.5% from 2023 to 2033, Viral hepatitis is expected to dominate the hepatic markers industry.
With a CAGR of 5.5% from 2023 to 2033, the hospitals is expected to dominate the hepatic markers industry.
Top Major Key Players and Their Effective Marketing Strategies:
The hepatic markers sector is a very competitive one, with many firms fighting for market share. Several significant participants in this industry comprise
Alpha Laboratories
Biobase Group
F. Hoffmann-La Roche Ltd
ELITechGroup
Horiba Medical
Laboratory Corporation of America Holdings
Randox Laboratories Ltd
Thermo Fisher Scientific Inc.
Abbott Laboratories
BD
Siemens Healthcare GmbH
Boston Scientific Corporation
PromoCell
Novus Biologicals
The major companies are heavily spending on research & development efforts to create innovative and inventive care with enhanced effectiveness, dependability, and affordability. They are also focusing on expanding their products related to hepatic markers and strengthening their distribution methods to fulfill shifting consumer expectations.
Tactical alliances and partnerships with other companies are becoming more common in the industry, allowing parties to leverage one another's strengths and expand their market influence.
Leading firms use consolidation and mergers to strengthen their market position and gain entry into new markets. The sector is expanding significantly in developing economies, particularly in India and China.
Major companies are expanding their distribution networks and building regional manufacturing sites to boost their presence in these regions. They are also concentrating on offering cost-effective tests to customers in these markets to get a competitive advantage.
Segmentation Analysis of the Hepatic Markers Market:
By Test:
Alkaline phosphatase (ALP)
Alanine transaminase (ALT)
Aspartate transaminase (AST)
Gamma-glutamyl transferase (GGT)
Others
By Indication:
Viral Hepatitis
Non-alcoholic Fatty Liver Disease (NAFLD)
Hemochromatosis
Others
By End User:
Hospitals
Laboratories
Others
By Region:
North America
Latin America
Europe
East Asia
South Asia
Oceania
The Middle East & Africa
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gionehospital · 1 month
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Don't Ignore Liver Problems! Find an Exceptional Specialist in Aurangabad
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Your liver is a powerhouse organ, silently operating away to detoxify your frame, produce critical proteins, and adjust severa important features. But when liver troubles get up, they are able to extensively effect your fitness and nicely-being. If you're experiencing symptoms that endorse a liver issue, do not ignore them! GI One Hospital, Aurangabad's main gastroenterology middle, has a team of incredible liver specialists equipped to help.  
Early Detection is Key:
Liver disease can often progress silently, with symptoms manifesting only in later stages. However, some common signs that might indicate a problem include:
Fatigue and tiredness
Loss of appetite or unexplained weight loss
Nausea and vomiting
Abdominal pain or swelling
Dark urine or pale stools
Yellowing of the skin and eyes (jaundice) 
Introducing GI One Hospital's Liver Specialists:
At GI One Hospital, we understand the importance of early diagnosis for ideal liver health. Our team of highly qualified and experienced hepatologists (liver specialists) is dedicated to providing comprehensive care for all your liver-related concerns. Our doctors have extensive training and expertise in diagnosing and treating a wide range of liver conditions, including:
Hepatitis (A, B, C)
Fatty liver disease (NAFLD and NASH)
Cirrhosis
Autoimmune hepatitis
Drug-induced liver injury
Hemochromatosis 
Advanced Diagnostics and Treatment Options:
We are equipped with advanced diagnostic tools to accurately identify the cause of your liver problem. These may include:
Blood tests
Liver function tests
Viral markers
Imaging studies (ultrasound, CT scan, MRI)
Liver biopsy (in some cases)
Once a diagnosis is established, our liver specialists will work with you to develop a personalized treatment plan. Treatment options may include:
Medications
Lifestyle modifications (diet, exercise)
Weight management
Minimally invasive procedures
Liver transplantation (in severe cases)
Why Choose GI One Hospital for Your Liver Care?
Experienced and Compassionate Team: Our team of hepatologists is dedicated to providing personalized care with a focus on patient comfort and well-being.
Advanced Technology: We utilize the latest diagnostic and treatment tools for accurate diagnosis and effective treatment of liver problems.
Comprehensive Care: We offer a complete spectrum of services under one roof, from diagnosis and treatment to follow-up care and management.
Focus on Patient Education: We empower patients with knowledge about their condition and treatment options.
Taking Care of Your Liver Health:
Your liver plays a critical role in maintaining overall health. If you're experiencing any concerning symptoms, don't hesitate to schedule an appointment with our expert liver specialists at GI One Hospital. Early detection and treatment can important improve results and ensure a healthier future for you.
Contact Us Today!
For more information or to schedule an appointment, visit our website at www.gionehospital.com
GI One Hospital - Your Partner in Exceptional Liver Care 
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Track 22: Liver Biopsy
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A liver biopsy is a medical procedure in which a small piece of liver tissue is removed for examination under a microscope. This procedure is typically performed to diagnose various liver conditions and diseases, assess the severity of liver damage, and determine the best course of treatment.
There are different methods of performing a liver biopsy:
Percutaneous biopsy: This is the most common method, where a thin needle is inserted through the skin and into the liver to collect a small sample of tissue. This procedure is usually done under local anesthesia, and the patient may be asked to hold their breath to reduce the risk of injury to surrounding organs.
Transvenous biopsy: In some cases, particularly when the liver tissue needs to be examined more closely or if there is ascites (fluid buildup in the abdomen), a biopsy may be performed through a vein in the neck or groin, using a special needle and imaging guidance.
Laparoscopic biopsy: In this method, a small incision is made in the abdomen, and a laparoscope (a thin, flexible tube with a camera) is inserted to guide the biopsy needle to the liver. This method may be used if other biopsy techniques are not possible or if a larger sample of liver tissue is needed.
After the biopsy, the liver tissue sample is sent to a laboratory for analysis by a pathologist. The pathologist examines the tissue under a microscope to look for signs of liver disease, inflammation, scarring (fibrosis), cirrhosis, infections, or tumors.
Understanding Liver Biopsy: Uses, and Risks
Liver biopsy is a diagnostic procedure used to assess liver health and diagnose various liver conditions. It involves the removal of a small sample of liver tissue for examination under a microscope. In this blog post, we will explore the liver biopsy procedure, its uses, and associated risks.
Uses:
Liver biopsy is used to diagnose a variety of liver conditions, including: Hepatitis (both viral and autoimmune) Cirrhosis Nonalcoholic fatty liver disease (NAFLD) Liver cancer Biliary tract diseases Genetic liver disorders
The results of a liver biopsy can help healthcare providers determine the severity of liver disease, guide treatment decisions, and monitor disease progression over time.
Risks:
While liver biopsy is generally considered safe, it does carry some risks, including:
Bleeding at the biopsy site Pain or discomfort Injury to nearby organs, such as the gallbladder or lungs In rare cases, infection or allergic reaction to anesthesia
Conclusion
In conclusion, liver biopsy serves as a crucial diagnostic tool in the assessment and management of liver diseases. Through the extraction of a small tissue sample, healthcare providers gain invaluable insights into the health of the liver, enabling accurate diagnosis, treatment planning, and disease monitoring.
Despite its importance, it's essential to acknowledge the potential risks associated with liver biopsy, including bleeding, pain, and the rare possibility of complications such as injury to nearby organs or infection. However, with proper preparation, skilled medical professionals, and diligent post-procedural care, these risks can be minimized.
Ultimately, the decision to undergo a liver biopsy should be made collaboratively between patients and their healthcare providers, taking into account individual medical history, the suspected condition, and the potential benefits and risks of the procedure.
By providing valuable diagnostic information, liver biopsy plays a vital role in the comprehensive care and management of liver diseases, contributing to improved patient outcomes and quality of life.
Important Information:
Conference Name: 14th World Gastroenterology, IBD & Hepatology Conference Short Name: 14GHUCG2024 Dates: December 17-19, 2024 Venue: Dubai, UAE Email:  [email protected] Visit: https://gastroenterology.universeconferences.com/ Call for Papers: https://gastroenterology.universeconferences.com/submit-abstract/ Register here: https://gastroenterology.universeconferences.com/registration/ Exhibitor/Sponsor: https://gastroenterology.universeconferences.com/exhibit-sponsor-opportunities/ Call Us: +12073070027 WhatsApp Us: +442033222718
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vijayanandsir · 2 months
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Understanding Liver Cancer: From Causes to Hope
Liver cancer, though not as widely discussed as other cancers, poses a significant health threat globally. It's crucial to break the silence and raise awareness about this complex disease. This blog aims to shed light on liver cancer, covering its types, causes, symptoms, treatment options, and available resources.
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What is Liver Cancer?
Liver cancer is the uncontrolled growth of abnormal cells in the liver. It can be primary, originating in the liver itself, or secondary, spreading from other organs. The most common type of primary liver cancer is hepatocellular carcinoma (HCC), accounting for around 80% of cases.
Causes and Risk Factors:
Several factors can increase your risk of developing liver cancer:
Chronic liver diseases: Hepatitis B and C infections, cirrhosis (scarring) due to alcohol abuse or nonalcoholic fatty liver disease (NAFLD).
Family history: Having close relatives with liver cancer increases your risk.
Aflatoxin exposure: A toxin produced by mold on certain foods can contribute to liver cancer risk.
Obesity and diabetes: These conditions are linked to an increased risk of NAFLD, which can progress to liver cancer.
Symptoms:
Early-stage liver cancer often shows no symptoms. However, as the cancer progresses, you might experience:
Abdominal pain or swelling
Loss of appetite and weight loss
Fatigue
Jaundice (yellowing of skin and eyes)
Easy bruising or bleeding
Nausea and vomiting
Diagnosis and Treatment:
Early diagnosis is crucial for better treatment outcomes in liver cancer. To ensure the most comprehensive and effective care, it is essential to consult with the Best Oncologist in Hyderabad. Doctors employ a range of diagnostic tests such as blood tests, imaging scans, and biopsies to accurately identify and assess the extent of liver cancer. The chosen treatment options are contingent on various factors, including the cancer stage, your overall health, and personal preferences. These may encompass surgical interventions, liver transplantation, ablation techniques (employing heat or other methods to destroy cancer cells), embolization (blocking the blood supply to the tumor), chemotherapy, and targeted therapy. Seeking guidance from the Best Cancer Specialist in India ensures that you receive personalized and state-of-the-art care tailored to your specific condition and needs.
Living with Liver Cancer:
A liver cancer diagnosis can be overwhelming, but remember you're not alone. Numerous support groups and resources are available to help you navigate your journey. These can provide emotional support, practical advice, and access to the latest treatment information.
Hope and the Future:
While liver cancer remains a serious illness, significant progress is being made in research and treatment. New therapies are emerging, offering hope for better outcomes and improved quality of life for patients.
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drpathikparikh · 3 months
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MASLD & Fibroscan (Liver Elastography) Demystified!!
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Fatty Liver is no longer an unheard term. The prevalence of fatty liver in India is approximately 30% and that means that nearly one in three person suffers from it. The disease is not as benign as the name and prevalence suggest. This disease is the most common liver disease worldwide. It is on path to become the number 1 reason for liver cirrhosis, liver cancer and liver transplant.
New Terminology
The disease has gone significant change in terminology and is now known as MASLD – Metabolic-Dysfunction Associated Steatotic Liver Disease and recently in 2023 the experts of the world met and proposed the following terminology for types of SLD (Steatotic Liver Disease) or Fatty Liver Disease
MASLD – Previously NAFLD or Fatty Liver
MASH – Previously NASH
MetALD – No previous terminology (Patients also take alcohol in addition).
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Risk Factors
MASLD and MASH is usually seen in patients who are obese, overweight and suffer from diabetes, hypertension, sedentary lifestyle, thyroid disease and is habituated to eating processed foods and high-fat high carbohydrate diet.
Progression
MASLD can progress over years to end stage liver disease and leads to complications similar to alcohol associated liver disease. It leads to cirrhosis and then ascites, pedal oedema, bleeding, jaundice, encephalopathy, liver cancer and may warrant liver transplant. In early stage when the disease is reversible, it has no symptoms and hence often ignored. When symptoms do develop, it is usually too late to reverse.
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Diagnosis
The diagnosis of fatty liver is based on a sonography or abdominal ultrasound where radiologist will let you know if you have fatty liver. Although, blood tests like liver function tests, lipid profile, HBA1c, CBC and others are often recommended to find out predisposing conditions and complications, it fails to give exact nature of underlying severity or stage of liver disease. For this, non-invasive tests are recommended. These tests are very important to understand the prognosis and treatment prescription. Following image is an idea about some of these tests.
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There is a lot of confusion currently in terminology of Fibroscan, Elastography and ARFI. I have created following flow chart to understand this difference.
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Fibroscan
It is Transient Elastography. It is the name of the machine which carries out the test of Transient Elastography. Unfortunately, since this is the first elastography technique and is accepted worldwide, the name is used synonymously for the technique. It is similar to XEROX and photocopy where XEROX is the name of the machine and the function is photo company. Fibroscan is produced by a French company called Echosens. This is the only approved and accepted modality worldwide.
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The currently available machines of Fibroscan (430,430 Mini, 502, 530, 630) provide following details
CAP – Controlled Attenuation Parameter – It tells the patient about the amount of fat in the liver. The ultrasound when gives Fatty liver Grade1,2 or 3, it is a subjective finding while CAP is an objective number which can be used to monitor treatment and risk stratification. A value above 230 is considered significant
LSM – Liver Stiffness Measurement– It tells you how stiff the liver has become. Stiffer the liver worse is the outcome. The vibration wave generated by the probe travels through the liver and the velocities then picked up to give a definite number. Usually, the number is less than 8 kPa. When the value crosses 14 kPa or above, the chances that the liver has irreversible damage are high. The risk of complications also increases when the value crosses 20 or above.
SSM – Splenic Stiffness Measurement – It is measured over the spleen and it gives risk of developing bleeding from the foodpipe and stomach secondary to liver cirrhosis. These values still require validation and widespread acceptance
The 402 version of the machine is outdated and no longer accepted. The machine has SMART EXAM to improve the efficiency, interoperability and accuracy.
Fibrotouch
Similar to Fibroscan, this machine is made in Asia and available also in India. It works exactly on the same principle as Fibroscan. Instead of CAP, the machine gives UAP. Although used frequently, a lot of Indian doctors, hepatologists and Gastroenterologists have raised questions about its accuracy.
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pSWE – Point Shear Wave Elastography
This is type of Elastography which radiologists carry out with the use of their sonography machine. The technique used is different from Fibroscan. Instead of Vibration, the machine uses Acoustic waves and the technique is known as ARFI. The machine provides an advantage of being able to do an ultrasound and elastography with the same machine but it cannot give CAP value and it requires validation to be used as a Fibroscan alternative as of now.
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MR Elastography
It is considered one of the best techniques. Availability although is a problem. Only few centres in India provide this facility. It is expensive.
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Treatment
The treatment of MASLD is lifestyle modification. If there is fibrosis on the above tests, your doctor might prescribe you medicines to protect the liver in addition. The control of predisposing factors is of paramount importance.
If you suffer from Fatty Liver – MASLD, please contact your Liver Specialist or Hepatologist
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