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Lenalid 5mg Capsule
lenalid | lenalid 5mg | lenalid 5mg capsule
Drug profile
lenalid 5mg
containing active substance known as Lenalidomide which is considered as thalidomide derivative and it is originated from Generic Revlimid.
Lenalidomide is a naturally established compound lenalid 5mg capsule
which plays important role in myeloma at first, later it is used for hematological disorders like myelodysplastic syndromes. lenalid is available in the strength of 5mg.
Trade name: Lenalid 5mg
Active ingredient: Lenalidomide
Strength: 5mg
Mfg: Natco pharma
Pack: 30 tablets in a container
Classified as: Anti-neoplastic drug
Prescribing information of Lenalid 5mg;
The most important therapeutic indication of Lenalidomide is given below as follows;
v In multiple myeloma
v In myelodysplastic syndrome
v In mantle cell lymphoma
Multiple myeloma:
lenalid 5mg
(Generic Revlimid) is used in myeloma condition by combining with dexamethasone
In myeloma patients with autologous hematopoietic stem cell transplantation, lenalid is used as a continuation therapy.
Myelodysplastic syndrome:
lenalid 5mg capsule
(Generic Revlimid), is also used in the therapy of patients with transfusion vulnerable anemia expected low or moderate exposure of myelodysplastic syndrome related to deletion 5q cytogenetic aberrant.
Mantle cell lymphoma:
lenalid 5mg (Generic Revlimid) is used in mantle cell lymphoma as a second line therapy. The patient’s disease conditions are reoccurred or advanced after prior two therapies like Bortezomib.
Mechanism of Lenalid 5mg;
lenalid 5mg capsule (Generic Revlimid), is a thalidomide analogue.
The pharmacological activity of Lenalid 5mg is;
Immuno modulatory
Anti-angiogenic activity
Anti-neoplastic activity
Immuno modulatory effect by;
Elevates the counts and activates the effect of T-cells and natural killer cells
Elevates the count of lenalid natural killer T cells
Prohibits the pro-inflammatory cytokines like TNF-alpha & IL-6 monocytes.
Anti-neoplastic activity by;
Prohibiting cell multiplication & activates https://pillsbag.com/ apoptosis of cancer cells in vitro and causes prohibition of cell growth in vivo, prominently to reduce in tumor strain.
Anti-angiogenesis;
Angiogenesis (cell development) is blocked by reducing the levels of VEGF, TNF-alpha & IL-6.
VEGF: Vascular Endothelial Growth Factor
Lenalidomide is expel its activity by inhibits the interpretation of cyclo oxygenase 2 (COX 2) in vitro, it may trigger the apoptosis directly lenalid 15mg by involving in prohibition of bone marrow stromal cell backing by anti-angiogenic and anti-osteoclastogenic activity & by Immuno modulatory effect
Absorption
After an oral administration of lenalid 5mg, the absorption occurs very quickly.
The peak plasma concentration time occurs between 0.5 to 6 hours after drug intake.
Distribution
Lenalid is bounds to human plasma protein at relatively 30%
Lenalidomide is occurs in semen after administration, at 2 hours & 24 hours after the dose of 25mg Lenalid 15mg.
Metabolism
The metabolism of Lenalidomide is occurs in limited range, mostly unchanged form of Lenalidomide is a major circulating substance present in the human body.
Excretion
The primary elimination https://pillsbag.com/ of Lenalidomide is occurs via renally.
Nearly 82% of radioactive dose is eliminated in urine within 24 hours; the two metabolites are excreted in 4.6% & 1.8%.
In myelodysplastic syndrome:The recommended dosage is 10mg of Lenalidomide should be taken as a single dose.
In renal damaged patients:In CrCl 30 to 60ml/min: 5mg https://pillsbag.com/ of Lenalidomide should be suggested for once a day.
In CrCl <30ml/min: 2.5mg PO as a single dose
In CrCl >60ml/min: No dosage adjustment is required.
Mantle cell lymphoma:The recommended dosage of Lenalid 15mg is 25mg should be administered orally as a single dose.
CrCl 30 to 60ml/min: 10mg PO single dose
CrCl <30ml/min: 5mg should be recommend as a single dose.
In ESRD: 5mg should be given.
Lenalid15mg caused side effectsThe major adverse effects;
Embryo fetal damage
Hematological toxicity
Venous & arterial thromboembolism
Elevation in mortality with CLL
Malignancies
Liver damage
Drug - drug interaction of Lenalid5mg
With digoxin:lenalid 5mg is combined used with digoxin causes increasing the plasma concentration of Lenalidomide lead to increase the adverse effects.
To avoid this problem, monitor the digoxin plasma concentration periodically during this concomitant.
Warfarin:There is no pharmacokinetic changes occurs during this concomitant of Lenalidomide with warfarin, but patients may get alteration lenalid in prothrombin time & INR. To avoid this condition, monitor the values frequently during this combinational therapy.
This type of concomitant treatment should be used cautiously to reduce the risk factors.Food drug interaction of Lenalid 5mg
Food should be avoided during chemotherapy of multiple myeloma;
Lenalid 5mg cause renal impairment;Food rich in https://pillsbag.com/ potassium
Avocados, bananas, spinach, citrus, tomatoes should be avoided
Whole grains, oats, bran cereals, sunflower seeds.
In tumor flare reaction:This condition may occurs in patients lenalid 5mg capsule who undergone Lenalidomide therapy, in CLL & lymphoma have chance of getting inflammation on lymph nodes, fever, pain, & rash
In liver toxicity:Constant hepatic function test should lenalid be done, before and during the therapies.
In this condition, treatment should be postponed and continue if required.
In tumor lysis syndrome:In this condition, patients must be monitored carefully and precaution should be provide.
In allergic conditions:lenalid 5mg treatment should be withheld or discontinue in case of angioedema, rash, bullous rashes.
In venous thromboembolism:In MDS, lenalid is used as a monotherapy, in this condition there is a chance of getting increased exposure of DVT & PE.
In hematological risk:Lenalid 15mg causes thrombocytopenia and lenalid neutropenia, patients receiving Lenalid 5mg for MDS should be completely examine by investigating blood counts weekly for first 8 weeks.
In MM patients should be monitored with counting blood cells for every 2 weeks for first 12 weeks and then monthly afterwards.
Storage and handling :Lenalid 5mg tablets should be stores lenalid 5mg at 20oC to 25oC; excursion between 15oC to 30oC.
Keep the container away from heat, moisture & light.
Missed doseThe missed dose of Lenalid 5mg should be avoided, and follow the regular dosing schedule.
Over dosage There is no special treatment for over dosage of Lenalidomide; In case of this condition patient must be provided with adjuvant therapy and lenalid 5mg capsule monitor the signs & symptoms frequently.
Contact Details :
Website :
https://pillsbag.com/
Address : Million Health Pharmaceuticals
Old.No.131,New.No.50,Pedariyar kovil street
Seven wells,Chennai-600001.Tamilnadu,India
Email : [email protected]
Phone Number : 9940472902
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Best Job Portal Development Services in Chennai - Apple Infoway
JOB PORTAL COMPANY IN CHENNAI
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Business Process Management in Chennai - Apple Infoway Pvt Ltd
BUSINESS PROCESS MANAGEMENT SYSTEM
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BUSINESS PROCESS MANAGEMENT
Business process management is controlling and looking at the processes present in an organization.this methodology is used in catastrophic situation to make sure processes are efficient & effective, that results in superior and more cost profitable organization.
HISTORY OF BPM
Business process management (BPM) originated from the domains of total quality management. Business process re-engineering is published in the 1980s. First Re-engineering is named as re-engine. Then re-engine using in the business process after then it is named as business process re-engineering. Life cycle management research started during 1990 and is still it is discussed a topic in IT fields. But in the 2000S The bpm services in chennai gets a strong position in the IT sector.
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How Business process management looks?Business process management is an activity; a practice - Business process management is something you do, not a thing you own or buy. It is characterized in many definitions as a practice. There was wide arrangement on this; well over 90% of the members expressed this view.
Business process management is about developing processes - It presumes the idea that you view business as a set of processes, and bpm company in chennai is the act of developing those processes. This is necessary: “skill” is different from “skill development”. This can be complicated. For example in competitive situations the two ideas are often intertwined - what is the act of playing cricket, if not also the act of trying to improve the way you play cricket? However, in other contexts it is easier to distinguish – the activity of driving is different than taking a driving course to improve the way you drive.
The indication is that Business process management is not about automating business process but about developing them. The same way that ‘reengineering’ a process is about not simply automating what is currently there. bpm company in chennai. However, auditing the process to find areas of advanced would still be an important part of business process management. bpm services in chennai is done by people distressed primarily with improvement of the process- A business process will associate many people, but how many of them are concerned with establishing it? Some will insist that advancement is everyone’s job.
Six way projection in BPMAnalyze
Re-design and model
Implement
Monitor
Manage
Automate
Types of Business ProcessICBPM
HCBPM
DCBPM
BPM TOOLSTop five main business process management tools are :Process Maker
Kiss Flow
Zoho Creator
Nintex
BizagiFirst conclusion of BPMCurrent trends in the business world are forcing organizations to focus on process if they want to remain successful. Many of these trends,
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such as the mobility of the workforce, rising customer expectations, and the speed at which business is conducted, are not likely to stop in the near future.
A good vision statement enables an organization to have a consistent view of what it wants the future to look like. It is impossible to reach the desired
bpm services in chennai
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Strategy maps can provide an excellent
bpm company in chennai
one-page communication vehicle to illustrate which processes are most critical in your organization, as well as the customer and financial results that developing these processes are expected to drive.
There are many reasons to adopt BPM which is greater efficiency, Process improvement, Standardized way of document process.Contact Details :Phone Number : +91 - 90872 99777
Address : Old.No. 131 , New.No.50, Pedariyar Koil Street,Seven Wells, Chennai-600001.
Tamilnadu, India.E-mail :
0 notes
Text
Best Web Portal Development Company in Chennai - Apple Infoway Pvt Ltd
Apple Infoway Pvt Ltd is a Best Web Portal Development Company & Expert in ERP Solutions , E commerce , Seo Services, Digital Marketing Training in Chennai.
0 notes
Text
Business Process Management in Chennai - Apple Infoway Pvt Ltd
BUSINESS PROCESS MANAGEMENT SYSTEM
bpm company in chennai|
bpm services in chennai
business process management in chennai
BUSINESS PROCESS MANAGEMENT
Business process management is controlling and looking at the processes present in an organization.
bpm company in chennai
this methodology is used in catastrophic situation to make sure processes are efficient & effective, that results in superior and more cost profitable organization.
HISTORY OF BPMBusiness process management (BPM) originated from the domains of total quality management. Business process re-engineering is published in the 1980s. First Re-engineering is named as re-engine. Then re-engine using in the business process after then it is named as business process re-engineering. Life cycle management research started during 1990 and is still it is discussed a topic in IT fields. But in the 2000S The
bpm services in chennai
gets a strong position in the IT sector.
BPM METHODOLOGYA Business Process Management methodology is the way to approaches our business process. Methodology
bpm company in chennai
means the business owner wants to select the right way of choosing the business or creating the business on its own.
How Business process management looks?Business process management is an activity; a practice - Business process management is something you do, not a thing you own or buy. It is characterized in many definitions as a practice. There was wide arrangement on this; well over 90% of the members expressed this view.
Business process management is about developing processes - It presumes the idea that you view business as a set of processes, and
bpm company in chennai
is the act of developing those processes. This is necessary: “skill” is different from “skill development”. This can be complicated. For example in competitive situations the two ideas are often intertwined - what is the act of playing cricket, if not also the act of trying to improve the way you play cricket? However, in other contexts it is easier to distinguish – the activity of driving is different than taking a driving course to improve the way you drive.
The indication is that Business process management is not about automating business process but about developing them. The same way that ‘reengineering’ a process is about not simply automating what is currently there.
bpm company in chennai
. However, auditing the process to find areas of advanced would still be an important part of business process management.
bpm services in chennai
is done by people distressed primarily with improvement of the process- A business process will associate many people, but how many of them are concerned with establishing it? Some will insist that advancement is everyone’s job. That is, the assistant should be thinking about how to improve the operations if possible.Business process management must be carefully defined as the activity done by people who actively and primarily look categorically at the business processes, and trying to improve them. Clearly those people must promote input from as many others as possible, but those others are not doing Business Process Management.
Six way projection in BPMAnalyze
Re-design and model
Implement
Monitor
Manage
Automate
Types of Business ProcessICBPM
HCBPM
DCBPM
How BPM works in live?BPM works in several criteria which include:Manufacturing – A product assembly process,
Finance – an invoicing process,
Health – a medical assessment
Banking – customer on-boarding,
Travel – trip booking,
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HR – a starters process, a leavers process, vacation request
Public Sector – application for a government service
Compliance – a safety audit, a legal check
BPM TOOLSTop five main business process management tools are :Process Maker
Kiss Flow
Zoho Creator
Nintex
BizagiFirst conclusion of BPMCurrent trends in the business world are forcing organizations to focus on process if they want to remain successful. Many of these trends,
bpm company in chennai
such as the mobility of the workforce, rising customer expectations, and the speed at which business is conducted, are not likely to stop in the near future.
A good vision statement enables an organization to have a consistent view of what it wants the future to look like. It is impossible to reach the desired
bpm services in chennai
future state if the management team cannot agree what the future state should be.Strategic assessment should have a large process component to it.
Strategy maps can provide an excellent
bpm company in chennai
one-page communication vehicle to illustrate which processes are most critical in your organization, as well as the customer and financial results that developing these processes are expected to drive.
There are many reasons to adopt BPM which is greater efficiency, Process improvement, Standardized way of document process.Contact Details :Phone Number : +91 - 90872 99777
Address : Old.No. 131 , New.No.50, Pedariyar Koil Street,Seven Wells, Chennai-600001.
Tamilnadu, India.E-mail :
0 notes
Text
Business Process Management in Chennai - Apple Infoway Pvt Ltd
Business Process Management is a discipline involving any combination of modeling,support of enterprise goals, execution, employees, spanning systems, computization and optimization of business.Business Process Management in chennai @ Apple Infoway Pvt Ltd
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SEM Services in Chennai | Google Promotion Company in Chennai
Apple Infoway is a one of the Best SEM Services Company in Chennai,Google Promotion Company in Chennai,Expert in PPC Services & Adwords Packages. Contact : +91 - 93800 37777
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Best Job Portal Development Services in Chennai - Apple Infoway
Apple Infoway is a Best Web Portal Development Company & Expert in ERP Solutions , E commerce , Seo Services, Digital Marketing Training in Chennai @ +91-9380037777.
0 notes
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Business Process Management in Chennai - Apple Infoway Pvt Ltd
Business Process Management is a discipline involving any combination of modeling,support of enterprise goals, execution, employees, spanning systems, computization and optimization of business.Business Process Management in chennai @ Apple Infoway Pvt Ltd
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SEM Services in Chennai | Google Promotion Company in Chennai
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SEARCH ENGINE MARKETING
A recent study has revealed that more 80% of people start their business in search engine marketing.sem services in chennai Search Engine Marketing is the process of getting website traffic by promoting through ads on Search engines.
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Address : Old.No. 131 , New.No.50,
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Seven Wells, Chennai-600001.
Tamilnadu, India.
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Best Job Portal Development Services in Chennai - Apple Infoway
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WEB PORTAL COMPANY IN CHENNAI
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Education portal
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Matrimonial portal
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Blog solution portal
Used cars portal
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Pedariyar Koil Street,
Seven Wells, Chennai-600001.
Tamilnadu, India.
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Best Job Portal Development Services in Chennai - Apple Infoway
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0 notes
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Best Web Portal Development Company in Chennai - Apple Infoway Pvt Ltd
Apple Infoway Pvt Ltd is a Best Web Portal Development Company & Expert in ERP Solutions , E commerce , Seo Services, Digital Marketing Training in Chennai.
0 notes
Text
Business Process Management in Chennai - Apple Infoway Pvt Ltd
Business Process Management is a discipline involving any combination of modeling,support of enterprise goals, execution, employees, spanning systems, computization and optimization of business.Business Process Management in chennai @ Apple Infoway Pvt Ltd
0 notes
Text
Best Web Portal Development Company in Chennai - Apple Infoway Pvt Ltd
Apple Infoway Pvt Ltd is a Best Web Portal Development Company & Expert in ERP Solutions , E commerce , Seo Services, Digital Marketing Training in Chennai @ +91-9380037777
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