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Immunity & minerals to boost our immune system
Immunity is a natural system in your body to prevent the assault of pathogens. Substances like viruses and bacteria are commonly known as pathogens. Every day we are in contact with these pathogens and some of them can be threatening. Our immune system can fail to fight them off.
Antigens are attached to the surface of these pathogens often stimulate an immune response.
Immune response is our body’s defence system to fight antigens and protect us. There are three types of immunity like passive immunity, innate immunity, and active or acquired immunity.
Passive Immunity: Refers to the capacity to resist pathogens by borrowing antibodies. For example, antibodies are transferred to a baby through breast milk from the mother. Another good example is immunoglobulin transfused from one person to another.
Innate Immunity: We are born with this immunity. These include body hair, skin, gastric acid, saliva. These often stand to respond quickly to defend against pathogens. This immune system doesn’t know the type of antigen.
Active/acquired Immunity: This type of immunity is developed from our immunological memory. When our body is exposed to a specific antigen, attached to a pathogen, the immune system develops antibodies for that specific antigen. If the same antigen attacks again, the body knows that specific antigen and has antibodies to fight off.
Essential Minerals to boost immune health:
Iron:
It is an important mineral required in our body to grow and develop. Hemoglobin, a protein in red blood cells is produced by iron. Hemoglobin carries oxygen from our lungs to all the parts of the body. Our body also needs iron to make some hormones.
Different types of Iron:
Ferrous Ascorbate
Ferrous Asparto Glycinate
Ferric Ammonium Citrate
Iron Polymaltose Complex
Ferric Pyrophosphate
Ferrous Bisglycinate
Zinc:
Zinc is an important nutrient that makes us healthy. It is found in cells in our body. Zinc is helpful in making our immune system stronger.
Different types of Zinc:
Zinc Citrate
Zinc Acetate
Zinc Aspartate
Zinc Bisglycinate
Magnesium:
Magnesium is required for multiple functioning in our body, including regular muscle and nerve function, blood sugar and blood pressure levels and even making protein, DNA, and bone density. Magnesium deficiency can indirectly or directly affect our immune health.
Different types of Magnesium:
Magnesium Acetate
Magnesium Citrate
Magnesium Aspartate
Magnesium Bisglycinate
These are the minerals that are used in boosting immune system. However, there are more minerals we will discuss in details in later blog posts.
Conclusion:
In this article we have seen the importance of immune system in our body and several minerals that are directly or indirectly involved in making this system healthy. These minerals can be found in our diet however sometimes we require them as supplements if the food doesn’t contain enough amount of that mineral.
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Nicorandil
Nicorandil a drug used to treat angina (chest pain or discomfort caused when your heart muscle doesn't get enough oxygen-rich blood). Nicorandil is a compound belong to the class of compounds commonly known as potassium channel activators.
There are multiple mechanisms causing the increased smooth muscle contraction involved in coronary vasospasm, including increased Rho-kinase activity.
Nicorandil is used in preventing & treating chest pain caused by angina (Angina, commonly known as angina pectoris, is often described as pressure, squeezing, heaviness, tightness or pain in our chest)
When other medications do not work or suitable for patient then in general Nicorandil is prescribe.
Nicorandil is only available on prescription and usually comes as tablets.
Nicorandil Facts
1. Nicorandil reduces the risk of having an angina attack by pumping the blood supply to our heart.
2. It's usual to take Nicorandil twice a day.
3. It is advisable to take Nicorandil twice a day (prescribed by your doctors)
4. Nicorandil if taken regularly can stop the deterioration of our heart conditions.
Who can take Nicorandil?
Nicorandil is not suitable for some patients. It is mostly prescribed to adults over 18 years old. But you should ask your doctor if you have the below issues:
• Have allergic reaction to Nicorandil or any other medicine even in the past.
• If you are suffering from Pulmonary Oedema (condition in which fluid build-up in our lungs)
• If you have low blood pressure aka hypotension.
· If you have a recent heart attack.
• If you have low blood potassium levels and if you are taking potassium supplements.
• Suffering from kidney problem.
• Suffering from glucose-6-phosphate dehydrogenase deficiency which is a genetic condition.
• Have a digestive condition affecting your large intestine also known as diverticular disease.
• If you are taking non-steroidal anti-inflammatory medicines regularly like corticosteroid or aspirin tablets.
When and how to take it?
Medical practitioners usually prescribe Nicorandil twice a day: once in morning and once in evening.
How much dose is safe to take?
Depending on how much Nicorandil works for the patient’s body.
If someone suffers from headaches, then he/she may be given a smaller starting dose of 5mg. This will increase from the next week.
How to take Nicorandil?
Patient can swallow the tablets whole with water. Nicorandil tablets ca also be taken with or without food.
What if you forget to take your tablets?
Whenever you miss your Nicorandil tablets, take them as soon as possible. However, if it is nearly time for your next dose then you must skip the missed dose. Never take a double dose together. It is recommended to set an alarm if you forget your doses often.
Side effects of Nicorandil
Like any other medications, Nicorandil also has some side effects. Not everyone experiences these side-effects. It is seen that one person in 100 suffers from side effects from Nicorandil tablets.
Usually the effects are mild and go away by themselves.
Consult with your doctor if the below side effects persist:
1. Headaches
2. Feeling weak or dizzy
3. Nausea & vomiting
4. Itchy red watery eye
5. Losing appetite or stomach pain.
Get Nicorandil powder from West Bengal Chemical Industries Ltd. A leading API chemical manufacturing company in India.
Grades Available:
BP: A white to off white crystalline powder.
IP: A white to off white powder
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Essential Mineral Copper
Copper helps maintaining our nerve cells and immune system. It also absorbs iron, form collagen, and helps producing energy.
Copper is a vital trace mineral needed for our survival. Mineral Copper is found in all of our body tissues and plays an important role in the making of red blood cells.
In our body, copper is found in our brain, heart, liver, kidneys, and skeletal muscle. Too much or too little amount of copper can adversely affect our brain functioning. However, the deficiency is rare but it can lead to cardiovascular disease and other problems.
Types of Copper:
1. Copper Propionate
Copper Propionate is available in different forms. It is used in different medicines. You can order Copper Propionate from West Bengal Chemical Industries, a limited company based in WB, India. It is available as API form. Appearance is green crystal powder with occasional friable lump.
2. Copper Bisglycinate
The molecular formula of Copper Bisglycinate is C4H8CuN2O4
Copper Bisglycinate, an optimally absorbed Albion mineral chelate supports blood vessel, bone, heart, nerve, and skin health.
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Multiple Zinc Types
It is found in cells in our body. Zinc is an essential nutrient that helps us stay healthy. Zinc is helpful in making our immune system stronger. During childhood, infancy, and pregnancy, our body requires zinc to grow and develop properly. We also require zinc to make proteins and DNA, the genetic material in all cells. Zinc also helps wounds heal.
Types of Zinc:
1. Zinc Citrate
The molecular formula of Zinc Citrate is C12H10O14Zn3
Zinc citrate is a zinc salt of citric acid. It is usually available as dietary supplements to treat zinc deficiency and source of zinc, an essential trace element. Get Zinc Citrate from WBCIL. Available in odourless, white to off white granular powder.
2. Zinc Acetate
The molecular formula of Zinc Acetate is C4H6O4Zn • 2H2O
Zinc acetate is used in medicines to treat and prevent zinc deficiency.
3. Zinc Aspartate
The molecular formula of Zinc Citrate is C8H14N2O8Zn. Zinc Aspartate is a chelated zinc supplement. It is a salt of zinc with the amino acid aspartic acid.
4. Zinc Bisglycinate
The molecular formula of Zinc Bisglycinate is C4H8N2O4Zn
Zinc Bisglycinate is used for the clinical dietary management of the metabolic processes of osteoarthritis (protective cartilage that cushions the ends of your bones wears down over time)
Order Zinc Bisglycinate as Active Pharmaceutical Ingredients (API) form from WBCIL Kolkata. It is available in white free-flowing powder.
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Essential Mineral Iron
Iron is an important element for our blood production. Around 70% of our body’s iron is found in the red blood cells of our blood called haemoglobin and in muscle cells called myoglobin.
Hemoglobin is helpful in transferring oxygen in our blood from lungs to all the tissues. Myoglobin on the other hand, accepts, stores, transports, and releases oxygen.
There are different sources from which we can get iron. Our main sources of iron are from food but if someone doesn’t get enough iron from food then supplement is used.
Different types of Iron:
1. Iron Isomaltoside
Patients suffering from chronic kidney disease (CKD) suffer from iron deficiency anaemia require treatment with intravenous iron. It has been proved that oral iron is not sufficient in these patients and that IV supplementation is more effective treatment.
The new IV iron, iron isomaltoside 1000, is composed of iron and chemically modified isomalto-oligosaccharides which have a mean molecular weight of 1000 Da and consist predominantly of 3–5 glucose units.
Order Iron Isomaltoside (available in API form) as API from West Bengal Chemical Ltd. The appearance is deep brown coloured free flowing powder.
2. Ferrous Asparto Glycinate
The molecular formula of Ferrous Asparto Glycinate is C2H5NO2.C4H7NO4.Fe.H. Ferrous Asparto Glycinate is used in multivitamin medicines and fatty acid product to prevent or treat vitamin deficiency before, during, and after pregnancy. Vitamins, minerals, and fatty acids play big roles in maintaining a good health.
Ferrous Asparto Glycinate is available as API form at West Bengal Chemical Industries Limited. The appearance is off white to light brown colour with occasional friable lumps.
3. Ferric Orthophosphate
Ferric Orthophosphate is widely used in food industry for making supplements. It is also used in farming as harmless pesticides (snail bait)
You can order Ferric Orthophosphate from West Bengal Chemical Industries Limited as API form.
4. Ferric Ammonium Citrate
The molecular formula of Ferric Ammonium Citrate is C6H5+4yFexNyO7
You can buy FAC from West Bengal Chemical Limited. The USP of Ferric Ammonium Citrate is thin, transparent, garnet red scales or granules or brownish-yellow red powder, deliquescent and affected by light.
5. Ferric Citrate
Ferric citrate contributes to the metabolism of iron by some organisms. Citrates, which are released by plant roots and by some microorganisms, can solubilize iron compounds in the soil. Like ferric hydroxide reacts with citrates to give form soluble complexes.
You can order Ferric Citrate from WBCIL as active pharmaceutical Ingredients form. It is available in greenish brown to brown hygroscopic powder. The molecular formula of Ferric Citrate is C6H6FeO7
6. Iron Polymaltose Complex
Iron (III) Hydroxide Polymaltose Complex in short Iron Polymaltose Complex is used to treat iron deficiency or iron deficiency anemia. It belongs to the group of oral iron preparations.
7. Ferric Pyrophosphate Citrate
Managing anemia is a big concern for patients with CKD undergoing hemodialysis. Iron-replacement agents is a strategy for anemia treatment for these patients.
Ferric pyrophosphate citrate, a novel iron-replacement agent, was approved by the US Food and Drug Administration in January 2015 for use in adult patients receiving chronic hemodialysis.
8. Ferrous Ascorbate
Ferrous Ascorbate with folic acid are combined as dietary supplements that replenish our body’s reserves of essential nutrients. The molecular formula of Ferrous Ascorbate is C12H14FeO12.2H2O
9. Ferrous Bisglycinate
Ferrous Bisglycinate an iron amino acid chelate. It is formed by the reaction of ferrous iron with 2 molecules of the amino acid glycine by a covalent bound in a process called chelation. Ferrous Bisglycinate has better patient compliance because of a fewer gastrointestinal tract side effects.
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Types of Calcium
Our human body requires multiple types of minerals aka essential minerals. Essential minerals are often divided up into major minerals (popularly called macro minerals) and trace minerals (called micro minerals).
Trace minerals are required in smaller amounts than major minerals. However, both of these two groups of minerals are equally important.
A balanced diet mostly provides all of the essential minerals to our body. One such mineral is Calcium.
Calcium is an important mineral found in our body. This mineral is found in many foods. Our body needs calcium to maintain strong bones and to carry out vital functions. All the calcium is stored in our bones and teeth. Calcium supports the structure & hardness.
The body also requires calcium for muscle movement and nerves to carry messages between our brain and each body part.
Types of Calcium:
1. Calcium Citrate
Calcium Citrate is the calcium salt of citric acid. It is usually used as a food addictive, preservative, even for flavor.
It is used in medicines for treating or preventing low blood calcium levels in those who do not get enough amount of calcium from diets. Low levels of Calcium Citrate can cause osteoporosis, rickets, hypoparathyroidism, and latent tetany.
2. Calcium Citrate Malate
Calcium Citrate Malate is a calcium supplement and is water-soluble. This is a calcium salt of citric acid (Citric acid is an organic compound) and malic acid with variable composition.
When Calcium Citrate Malate is dissolved, it releases calcium ions and a calcium citrate complex. Calcium ions are directly absorbed into intestinal cells. The citrate complex enters the body through the para-cellular absorption.
Calcium Citrate Malate is a little different from Calcium Malate and other calcium salts. The European Food Safety Authority has concluded that calcium citrate malate is slightly more bioavailable that other forms of supplements containing calcium.
3. Calcium Acetate
Calcium Acetate is a chemical compound that is a calcium salt of acetic acid (Acetic acid is the second simplest carboxylic acid).
Calcium Acetate has the formula Ca(C2H3O2)2. The systematic name of Calcium Acetate is Calcium ethanoate and its older name is acetate of lime.
Calcium Acetate is prepared by soaking calcium carbonate or hydrated lime in vinegar.
4. Calcium Aspartate
The molecular formula of Calcium Aspartate is C8H12CaN2O8
The API form of Calcium Aspartate is white crystalline powder. Calcium Aspartate has high absorption rate in comparison to other calcium. You can get Calcium Aspartate as API from West Bengal Chemical Industries Ltd.
5. Calcium Asparto Glycinate
Calcium Asparto Glycinate is an important calcium and is used in medicines to support the functioning of our body tissues. It is also used in supplements to support our nerves, muscles, and all connective tissues.
6. Calcium Propionate
It is an organic salt used as a food additive. Calcium propionate helps preserve foods, generally baked goods, by interfering with the growth and reproduction of microorganisms, such as bacteria, molds, and fungi.
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Buy Ferric Ammonium Citrate to produce medicine
Order Ferric Ammonium Citrate as API (Active Pharmaceutical Ingredient) from West Bengal Chemical Industries Ltd (WBCIL).
The USP grade available is thin, transparent, garnet red scales or granules or brownish-yellow powder, effected by light.
The BP grade available is transparent, dark red scales or granules or brownish red powder. Also odourless, become liquid in moist air and affected by light.
BPC grade available is green powder with granules, odourless, tends to become liquid in moist air, and is affected by light.
The injectable grade of Ferric Ammonium Citrate is also available.
Shelf Life: 36 Months
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Nicorandil benefits, uses, and side-effects
Nicorandil is a drug used in treating angina. Nicorandil, a compound belonging to the class of compounds known as potassium channel activators.
Angina disease is chest pain that results from episodes of transient myocardial ischemia (Ischemia is generally caused by problems with blood vessels, with resultant damage to or dysfunction of tissue i.e. hypoxia and microvascular dysfunction.).
This can be caused by diseases such as coronary, atherosclerosis, aortic stenosis. Angina commonly arises from vasospasm of the coronary arteries. There are multiple mechanisms causing the increased smooth muscle contraction involved in coronary vasospasm, including increased Rho-kinase activity.
Nicorandil is used in preventing and treating chest pain caused by angina (Angina, commonly known as angina pectoris, is often described as pressure, squeezing, heaviness, tightness or pain in our chest)
When other heart medicines do not work or suitable for patient then doctors in general prescribe Nicorandil.
Nicorandil is only available to us on prescription and usually comes as tablets.
Nicorandil Facts
1. Nicorandil is helpful in reducing the risk of having an angina attack by pumping the blood supply to our heart.
2. It's usual to take nicorandil twice a day.
3. Nicorandil if taken regularly can stop the deterioration of our heart conditions.
4. It is advisable to take Nicorandil twice a day (listen to your doctors)
Who can take Nicorandil?
Nicorandil may not be suitable for some people. It is usually prescribed to adults over 18 years old. But you should ask your doctor if you have the below issues:
· Have allergic reaction to Nicorandil or any other medicine even in the past.
· If you are suffering from Pulmonary Oedema (condition in which fluid build-up in our lungs)
· If you have a recent heart attack.
· If you have low blood pressure aka hypotension.
· If you have low blood potassium levels and if you are taking potassium supplements.
· Suffering from kidney problem.
· Suffering from glucose-6-phosphate dehydrogenase deficiency which is a genetic condition.
· Have a digestive condition which is affecting your large intestine also known as diverticular disease.
· If you are taking non-steroidal anti-inflammatory medicines regularly like corticosteroid or aspirin tablets.
When and how to take it?
Doctors usually prescribe Nicorandil twice a day: once in the morning and once in the evening.
How much dose is safe & you can take?
Depending on how much Nicorandil works for your body.
If you suffer from headaches, then you may be given a smaller starting dose of 5mg. This may increase from the next week.
How to take Nicorandil?
You can swallow the tablets whole with water. You can also take Nicorandil tablets with or without food.
What if you forget to take your tablets?
Whenever you miss your Nicorandil tablets, take them asap although if it is nearly time for your next dose then you should skip the missed dose. It is never advisable to take a double dose together. We recommend you to set an alarm if you forget your doses often.
Side effects of Nicorandil
Like any other medicine, Nicorandil also has some side effects. However not everyone experiences them. It is seen that one or more people in 100 suffer from side effects from Nicorandil tablets. Usually these effects are mild and go away by themselves.
You can consult with your pharmacist or doctor if the below side effects really bothering you:
1. Severe headaches
2. If feeling weak or dizzy
3. Feeling nausea and vomiting
4. Itchy or red watery eye
5. Loss of appetite or stomach pain.
Buy Nicorandil powder from West Bengal Chemical Industries Ltd. A chemical manufacturing company in India.
Grades Available:
BP: A white to off white crystalline powder.
IP: A white to off white powder
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Iron Isomaltoside in Treating Anaemia
Iron deficiency anemia commonly known as IDA is a common problem related with multiple chronic disorders also includes chronic kidney disease (CKD). The main cause of anemia in patients with CKD are erythropoietin and iron deficiencies and also a decreased responsiveness to the actions of erythropoietin.
Some of the reasons for which people suffer with anemia are bad quality of life, long time suffering from disease. According to WHO, Anaemia results from a lack of red blood cells or dysfunctional red blood cells in the body. Especially women from the third world countries suffer the most due to blood loss during menstruation.
Treatment is required for anemia patients. In general iron supplement is given to the patients. Treatment of oral iron is adequate for some patients but there are side effects like intolerance, inflammation, etc.
The International guidelines suggest IV iron preparations as the preferred option in the correction of Iron Deficiency Anemia in several of these circumstances especially when there is a high iron demand, since it is more effective, tolerated by patients, and improves the quality of life to a greater extent than oral iron supplements.
(Iron Infusions first came about in the early twentieth century)
Iron Isomaltoside was introduced in Europe in 2010. It consists of iron and a carbohydrate moiety in which the iron is tightly bound in a matrix structure.
This enables a controlled and slow release of iron to iron-binding proteins that avoids potential toxicity from release of labile iron.
The strongly bound iron within the Iron Isomaltoside formulation allows flexible dosing. You can use high dosing (single doses of 1–2 g) over a short time period without any harm. Compared to compounds in which iron is more loosely bound in the complex, the iron Isomaltoside complex potentially leads to generation of less oxidative stress and less immunological toxicity.
In the European Union, iron Isomaltoside is administered with a maximum single dosage of 20 mg/kg actual body weight.
The dose flexibility and possibility of providing full iron correction over a short time period in one visit make iron Isomaltoside highly convenient for both the patients and health-care professionals.
Several clinical trials, mainly short term, have been reported for Iron Isomaltoside where it has been shown to be well tolerated and to improve markers of IDA in patients receiving dialysis.
WBCIL is a leading manufacturer of iron Isomaltoside and also exports to countries like Egypt, UAE, US, etc. It is available in deep brown coloured free flowing powder. Packing size of iron Isomaltoside is 20 kg in sterile HDPE drum. The shelf life of Iron Isomaltoside is 36 months.
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Iron Isomaltoside
• Chronic Kidney Disease - functional iron deficiency should be corrected before ESA therapy, management of anaemia
• Antenatal and postpartum – haemorrhage, delayed wound healing, reduced quality and quantity of lactation
• Gastroenterology - Inflammatory (Crohn’s & colitis), acute/chronic blood loss
• Pre- and post-operative – rapid increase in Hb levels & alternate to blood transfusion
• Gynecology Oncology – improved response to erythropoietic proteins
• Chronic Heart Failure – reduced left ventricle ejection fraction, improved functional capacity, low side effect
• ITU, care of the elderly, palliative care – rapid increase in Hb levels & alternate to blood transfusion
In General:
Requirement of rapid iron replacement
Ongoing occult blood loss
May delay investigative procedures
Interactions with many common oral drugs
May be inadequate during ESA therapy
Accelerated erythropoiesis can increase demand for iron beyond the amount supplied orally
Gastrointestinal adverse events
Can affect over 50% of patients
Can adversely affect nutritional intake
Improved if iron tablets are taken with food, but this decreases absorption
Compliance
Pill burden: usually 2 or 3 tablets per day
Affected by gastrointestinal intolerance
Oxidative stress
High oral iron doses can saturate the iron transport system if the iron is rapidly released, resulting in oxidative stress
When parental iron
• Indicated for treatment of iron deficiency when oral iron preparations are ineffective or cannot be used
• Comparative clinical trials show a faster and more prolonged response with IV iron than with oral iron
• IV iron is more effective, better tolerated and improves quality of life to a greater extent than oral iron
• Concerns regarding allergic reactions
Why Iron Isomaltoside?
• very low immunogenic potential and a very low content of labile and free iron and therefore less oxidative stress and potentially better long-term safety
• enables to be administered as a rapid high dose infusion in doses exceeding 1000 mg without the application of a test dose
• offers considerable dose flexibility, including the possibility of providing full iron repletion in a single infusion (one-dose iron repletion)
• consists of iron and a carbohydrate moiety where the iron is tightly bound in a matrix structure
• enables a controlled slow release of bioavailable iron to the iron-binding proteins, with potentially a reduced risk of free iron toxicity
Pharmacodynamic properties
• Iron Isomaltoside solution for injection is a colloid with strongly bound iron in spheroidal iron-carbohydrate particles
• The formulation contains iron in a complex that enables a controlled and slow release of bioavailable iron to iron-binding proteins with little risk of free iron
• Each particle consists of a matrix of iron(III) atoms and isomaltoside pentamers – the chelation of iron(III) with carbohydrate confers to the particles a structure resembling ferritin that is suggested to protect against the toxicity of unbound inorganic iron(III)
• The iron is available in a non-ionic water-soluble form in an aqueous solution with pH between 5.0 and 7.0
• Evidence of a therapeutic response can be seen within a few days of administration as an increase in the reticulocyte count. Due to the slow release of bioavailable iron serum ferritin peaks within days after an intravenous dose and slowly returns to baseline after weeks
Pharmacodynamic properties (cont.)
• Following IV administration, Iron Isomaltoside 1000 is rapidly taken up by the cells in the reticuloendothelial system (RES), particularly in the liver and spleen, from where iron is slowly released
• The plasma half-life is 5 hr for unbound circulating iron and 20 hr for total iron (bound and circulating)
• Circulating iron is removed from the plasma by cells of the reticuloendothelial system which split the complex into its components of iron and isomaltoside 1000
• The iron is immediately bound to the available protein moieties to form haemosiderin or ferritin, the physiological storage forms of iron, or to a lesser extent, to the transport molecule transferrin
• Due to the size of the carbohydrate–iron complex, intact Iron Isomaltoside 1000 is not eliminated via the kidneys
• Small quantities of iron are eliminated in urine and faeces
• The carbohydrate component, isomaltoside 1000, is either metabolized or excreted
Why Ideal IV..?
• Capable of delivering a wide dosing range to allow a single visit iron correction dose
• Test dose not necessary
• Controlled slow release of bioavailable iron to the iron-binding proteins, with potentially a reduced risk of free iron toxicity
• A fast infusion, and minimal potential side effects including low catalytic/labile iron release and negligible risk of anaphylaxis
• They should be convenient for the patient and the health care professional
• Cost effective for the health care system
• Each 1 ml contains 100 mg iron
Snapshot
• Tightly bind iron – more doses in one shot
• Each 1 ml contains 100 mg iron
• Test dose not necessary
• One dose Iron Repletion
• No ceiling in dose (upto 2000 mg can be given in 1 shot and 3000 mg in cumulative dose)
• Can be administered as a single infusion in 30-60 minutes for doses upto 20mg iron/kg body weight
• Negligible Hypophosphatemia Episode
• An important component of the strategy as an alternative to blood transfusion
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Common Uses of Ferric Orthophosphate
Ferric Orthophosphate is usually known as Iron Phosphate (In science, a phosphate is an anion, salt, useful gathering or ester got from a phosphoric corrosive. It most regularly implies orthophosphate, a subordinate of Orthophosphoric corrosive H. 3PO. 4.).
Ferric Orthophosphate is a vital mineral used in different industries like food, pharma, farming, etc. It is added to nutritional supplements for treating anaemia commonly known as iron deficiency.
Ferric Orthophosphate is also used in sports industry as performance enhancers (It helps boosting the stamina of a sportsman/athlete)
Ferric Orthophosphate in treating Anaemia
Anaemia is very common among the women population due to their menstruation cycle. So they have to get iron supplement from external sources.
Iron is an important mineral in human body. It is one of the most important minerals in a human body. Iron in the form of haemoglobin helps red blood cells in carrying oxygen from your lungs to the cells and remove carbon dioxide from human body.
Someone with deficiency of iron most probably can also suffer from anaemia. Patients who are suffering from anaemia often feel fatigue because not enough amount of oxygen is supplied to their cells.
People who are suffering from anaemia if do not get enough iron in their diet must need to consume iron from supplements to get the mineral to their body. Ferric Orthophosphate is a very crucial iron supplement that is consumed to treat iron-deficiency anaemia.
It is often seen that those who are vegetarians do not get enough iron because iron is mostly available in non-vegetarian food items.
Ferric Orthophosphate & Performance
To enhance the blood flow of a human body, Ferric Orthophosphate is usually added to supplements. These sport enhancers improve the oxygen movement during heavy exercise like weight lifting, running, etc.
It is also used in treating certain types of memory loss and learning issues in children suffering from low iron levels. There is no solid proof that Ferric Orthophosphate is useful in treating problems that are related to non-iron like ADHD (Attention Deficit Hyperactivity Disorder)
Other Uses of Ferric Orthophosphate
Ferric Orthophosphate is a vital substance in farming because it is used to kill slugs and snails that are responsible for destroying crops.
It has already been approved to use on organic crops because it is not harmful to pets, wildlife, and humans.
In 2005, US Department of Agriculture added Ferric Orthophosphate to the National list of approved substances and to be used in the organic farming.
Where to get Ferric Orthophosphate?
West Bengal Chemical Industries Ltd is a leading supplier of Ferric Orthophosphate in India and also exports to countries like Egypt, US, UAE, Bangladesh, etc.
Buy Ferric Orthophosphate from WBCIL. The shelf life is 36 Months. Packing size: 25 kg in HDPE bag/drum.
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Study of Ferrous Asparto Glycinate
Iron Deficiency Anaemia in short known as IDA is a very common nutritional disorders worldwide. It is recorded that it is almost one-half of anaemia cases.
According to the World Health Organization (WHO), Iron Deficiency Anaemia with haemoglobin levels <11 g/dl, is one of the main causes of disability (UNU/UNICEF/WHO 2001).
There was a study in which it was noted how safe oral Ferrous Asparto Glycinate and Ferrous Ascorbate among pregnant women who are suffering with iron deficiency anaemia (IDA). In the study, researchers gathered 73 pregnant women at 12 to 26 weeks’ gestation. The group of women were divided into two arms. Women in one group was given Ferrous Ascorbate whereas another group was treated with Ferrous Asparto Glycinate for a period of 28 days.
On day 14 and 28, the mean rise in haemoglobin & Ferritin levels was evaluated. The study found that a significant higher levels of Ferritin and haemoglobin were found in the group who were treated with Ferrous Asparto Glycinate as compared to those treated with Ferrous Ascorbate. So it was concluded that Ferrous Asparto Glycinate is an effective iron amino acid chelate in managing IDA in pregnant women as compared with Ferrous Ascorbate. In spite of these findings, we need a large scale clinical trials are required to confirm the findings.
Ferrous Asparto Glycinate is Off white to light brown colour free flowing powder with occasional friable lumps. If you want to buy Ferrous Asparto Glycinate in a large quantity, then contact West Bengal Chemical Industries Ltd. WBCIL is leading supplier of chemicals in India and exports to other countries.
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Ferric Ammonium Citrate
Ferric ammonium citrate is a chemical having yellowish brown to solid red with a faint-odor of ammonia. FAC chemical is soluble in water.
Uses of Ferric Ammonium Citrate
Ferric Ammonium Citrate is widely used in medicine, to make blueprints, and as food-addictive.
Ferric Ammonium Citrate is used to prevent
Ferric Ammonium Citrate prevents iron-deficiency, and anaemia. There may be other uses of this medication. You must ask your doctor or pharmacist for more information.
You can buy Ferric ammonium citrate from WBCIL (West Bengal Chemical Industries Ltd) in the form of spray dried homogeneous powder. WBCIL is a leading manufacturer of Ferric ammonium citrate in India.
Ferric Ammonium Citrate in treatment
Ferric Ammonium Citrate is used in treating anemia (a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your body's tissues), complication during pregnancy, hypochromic, and hematologic (Hematologic diseases are disorders which primarily affect the blood & blood-forming organs)
Hazards:
The hazard of FAC is the threat to the environment. This is a primary hazard. If it spreads in the environment, then the first and immediate step is to limit its spread.
USP: Transparent, thin, garnet red scales or brownish-yellow red powder, affected by light.
Packing Size – 25 kg in HDPE bag/drum
Precautions: Keep Well Closed, protected against light, dry and at room temperature.
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Calcium Propionate In Food Industries
Calcium Propionate is an organic salt (naturally occurring) which is formed by a reaction between Propionic Acid and Calcium Hydroxide.
It is a generally used as a food addictive – Popularly known as E282 for preserving multiple food products. The list of those food products given below:
Dairy Products: powdered milk, cheese products, yogurt, whey, and many more.
Beverages: fruit drinks, soft drinks, etc.
Baked goods: pastries, breads, muffins, etc.
Alcoholic drinks: malt beverages, beers, cider, wine, etc.
Processed meats: hot dogs, lunch meats, ham, etc.
Calcium Propionate is used to extend the shelf life of many goods by stopping/slowing-down the growth and reproduction of molds and many other microorganisms that destroy the food products.
Mold and bacteria are a big concern for the baking industry mainly because baking provides conditions that are ideal for the growth of mold and bacteria.
Calcium propionate has been approved for use by World Health Organization (WHO), Food & Drug Administration (FDA), and Food and Agriculture Organization of the United Nations (FAO).
How safe is it to consume?
Calcium Propionate was studied extensively by the Food & Drug Administration before it was considered safe to be used in the food industry.
There was a study on animals that showed that feeding rats (1-3 grams) of Calcium Propionate daily over 4 to 5 weeks had no impact on their growth.
There was a one-year study on rats which proved that taking a diet comprising 4% Calcium Propionate, a higher percentage than human would consume daily had no toxic effects.
Most of the studies in lab on Calcium Propionate and toxicity have proved that it is not that toxic, except a few when used exceptionally higher amounts.
In one instance, researchers injected a very high amount of Calcium Propionate into the yolk sacs of chicken embryos, resulting in abnormalities in the chicken.
Our body cannot store this Calcium Propionate which means it does not build up in our cells. The substance is broken down by our digestive tract and instantly absorbed, metabolized, and at last eliminated.
The Downsides
In general, Calcium Propionate is safe to consume with almost no side effects.
In some situations, it can cause adverse effects like migraines and headaches.
In one study on human, Calcium Propionate intake can lead to the increased production of insulin and glucagon (hormones that stimulates glucose release). This makes our body insulin resistance which is a condition in which our blood cannot use insulin properly, which may lead to Type-2 diabetes.
There was a study on 27 kids. It was found that some experienced restlessness, irritability, poor attention, and irregular sleep after consuming bread daily containing Calcium Propionate.
More studies are required in in this area before it is determined that Calcium Propionate possibly cause bad effects on our body.
It is not supposed to cause any harmful effects on our body so it is safe to be used in our food.
The Conclusion:
Calcium propionate is an organic salt that is not so harmful and is used as a food addictive. It is helpful in preserving foods (baked ones) by interfering growth of microorganisms like fungi, molds, and bacteria. Calcium propionate is safe to use with little to no side-effects for most people. WBCIL is a leading manufacturer of Calcium Propionate in India.
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Ferric Orthophosphate an Iron with many uses
Ferric Orthophosphate, is a popular mineral widely known as iron phosphate. This mineral is an inorganic chemical containing iron.
It is also added to performance enhancers for improving the athletic abilities and stamina. Ferric orthophosphate is the only white iron used in food products like Horlicks, Complan.
Iron Phosphate has many other food and medical uses as well as uses outside of food and medical treatments
Ferric orthophosphate is very important and for various functioning of the human body. It is also used as harmless pesticides snail baits but is not harmful for farming.
This mineral is used to treat anaemia or iron deficiency by adding to nutritional supplements.
The iron can be poisonous if taken in large dosages. This is a common mineral that leads to iron poisoning in kids who ingest large amounts of vitamins because the vitamins look or taste like candy which they love.
West Bengal Chemical Industries ltd in short WBCIL is a lead producer of Ferric Orthophosphate and supplies in India and export to other countries.
Call: +91 (33) 4025 1700 / +91 (33) 4025 1537
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