Considering their IRL counterparts, we think there's a very good chance that since Heart was Rad God's previous host, while she got transmitted to Mad Rat via bits of her in the heart tissue. There's not a whole lot else going on in that operation besides the heart transplant, after all, and we doubt that the doctor had any extra contamination around to potentially transmit her. We know that she says she lives in rats, specifically, but there's One Specific Protozoan she's based off of, and cats are the definitive host o f Toxoplasmosis Gondii.
Given the givens, it's entirely possible she simply doesn't present the same symptoms cross-species, and a symbiotic host that offers more benefits to her just... won't experience the same trip, especially since trying to feed your cat host to a cat doesn't really offer any benefit to either of you. With Heart, he's probably either asymptomatic or just only experiencing symptoms that don't particularly affect his day-to-day life, possibly in a way where he wouldn't have even known he was playing host to a parasite if it wasn't for the situation with Mad Rat.
Would it be weird for him to be... aware of that, postgame? To know that he's carrying a parasite with the potential to majorly fuck up any rats that might contract it? Is there a proper way to react to the knowledge that you're carrying a hallucinogenic parasite in you that'll cause major issues for any rat you might infect? Would he even, like... figure out the whole "asymptomic/mostly asymptomic carrier" thing before later? These are the questions we really need to ask.
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