#their personal image via either genuinely expressing their feelings on certain topics or simply using them for clout

[mwolf0epsilon]

"Star Wars isn't dead y'all are just haters" "Disney saved Star Wars" "It's the Woke Agenda that ruined Star Wars"

My mans, Disney single-handedly destroyed the Sequel Trilogy despite the Force Awakens being the gateway to something potentially fantastic; MCU'd the Mandalorian (a story which originally had nothing to do with the Prequel and OG Trilogy aside from sharing a universe and exploring a sect of a completely different culture/ideology); ego-boosted both Filoni and Favreau to the point where their OC Verse is not only canon but openly disregarding the Star Wars Universe Bible/Lore; gave us a snippet of what an extremely misunderstood indigenous culture is actually like (instead of portraying them as the savages one of the white leads mislabeled as animals that deserved to be slaughtered) only to then wipe out the tribe we got to know for no reason other than shock value thus alienating indigenous/poc viewers in the most disrespectful way possible; completely threw away the entire message of TCW (that being a clone does not make you incapable of being your own person who has their own thoughts, ideals, moral compass and overall identity) by making TBB (a show that does have it's strong points in set design, soundtrack orchestration and overall sound design, but is extremely weak on both characterization and storytelling because they either make the meaningful plot points stretch too thin or focus on the wrong character completely) their go to show marketed for kids instead of the actual kids programming that people shit on for being for, surprise, kids; constantly disregards valid critique from their consumers (to the point where infighting in the Fandom has gotten extremely ugly) that people either give up on interacting completely or simply vanish and take all their things with them (because no one seems to understand where these critiques come from, or how being unable to admit your special little show is imperfect is actually not a good thing for both you and others).

This isn't even accounting for the fact the Fandom seems to have doubled in it's overall toxicity since Disney took over. Which is par for the course when a mega corporation takes hold of something that started out extremely political in nature anyway. The Cash Cow machine needs feeding after all...

#Eps Talks About: #Funny enough this started as an argument between my sisters #One of which isn't a Star Wars fan and the other who is an OJ and Prequels fan #My mom (who was the one to introduce us to star wars mind you) and I watched from the sidelines #Mom didn't care because she doesn't like Modern Star Wars stuff but I ended up putting an end to the argument #My younger sister is right that Disney put too much emphasis on SELLING Star Wars to newer generations to a detrimental degree #but that doesn't mean they invalidate what came prior to their shitshow or the message SW was created to uphold #in fact Andor and SW Visions S2 made a point of being the best homages to the OJ trilogy thus far by being very political in their messages #But my older sister is also right that the state of Fandoms these days is very much a US vs THEM situation in terms of how people make #themselves heard and how meeting in the middle is virtually impossible which is very much a product of social media and how people conduct #their personal image via either genuinely expressing their feelings on certain topics or simply using them for clout #It is a case of locking yourself in a room with an 'adversary' and trying to see who can scream the loudest until someone loses their voice #I love star wars but that doesn't mean I'm blind to the fact star wars also kinda sucks lmao but oh well these are just my thoughts that #I'm letting loose because I'm already pissed off from something else going wrong today and have no patience for some of the rancid shit #that keeps cropping up in either tags or posts I find in and out of Tumblr Dot Com

[pluto-art]

- PINKY AND THE BRAIN - EXPERIMENTS -

Below the cut is a personal project on the much more morbid side. Animal lab experimentation is always something I’ve found equal parts horrible and fascinating. Once in a blue moon, I’ll do research on the subject out of curiosity and/or for storytelling purposes. Even as a kid, I found this of interest, and when watching Pinky and the Brain I was always a bit disappointed that we never saw more of what the characters actually went through in the lab during the day. Granted, there’s a reason as to why this was never shown, as a child audience had to be kept in mind, yet still I pondered about it....

Over the last few days, I’ve been churning out compositions based on internet findings -- old and new experiments that rats and mice are put through, many of them humane, some of them very much not. It was an eye-opening journey for me artistically and otherwise, discovering what I’m comfortable drawing and what I never want to sketch again, as well as learning more about this realm of the scientific world.

WARNING: SOME GRAPHIC CONTENT BELOW THE CUT. If needles, patients dealing with the effects of cancer, and general portrayals of pain bother you, I wouldn’t bother venturing onward. I not only drew out experiments that the characters might have gone through, but also describe all of my findings in detail and provide video footage to go along with it. While I didn’t go full-on vivisection or anything, some of this might still be disturbing, so I’m taking extra precaution.

All of the images below are “color-coded” and graded. The experiments start out fairly tame, then get worse... and worse... and worse. The backgrounds reflect this, going from fairly light to quite dark.

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Experiment #1 - Tail Flick Test

A fairly harmless experiment. The subject is mostly restrained, leaving only their tail exposed. An intense light beam is projected onto the exposed appendage, with the animal flicking their tail when the pain/heat becomes too much. This test is utilized in basic pain research and to measure analgesic effectiveness.

I wanted Brain to wear an expression of deep apathy -- he’s done this a million times and will probably do it a million times more. At this point, he doesn’t even care anymore.

For the background, I simply copied an environment in one of the videos I found.

Video example: https://www.youtube.com/watch?v=BzrA1tDTfkQ

Experiment #2 - Rotarod Performance Test

Another experiment that’s generally harmless. One or multiple subjects are placed on elevated rotating rods so as to measure such things as endurance, balance, grip strength, and more.

I imagine Pinky would enjoy this test, as he’s familiar with running on a wheel and actually enjoys more strenuous activities. Brain, on the other hand, would only participate via sheer force. He’d also be more prone to fall after a shorter period of time, getting tired faster than his cage mate.

Video example: https://www.youtube.com/watch?v=v56MtrmWAs0

Experiment #3 - Shot (General)

Nothing special. Just Brain about to get shot.

This is all highly exaggerated, of course. A mouse would simply be held firmly, not strapped down, for a simple injection. Also, I can’t imagine why they’d be shot in the face, although Meg told me that scientists tend to draw blood samples from a mouse’s cheek. Need to look that up. I wasn’t at all going for accuracy here, but rather how it might feel -- how scary it would be.

Experiment #4 - Sciatic Nerve Constriction

An experiment in chronic neuropathic pain, due to the central or peripheral nervous system sustaining damage. Under anesthesia, the animal’s sciatic nerve is exposed via skin incision. The connective tissue between the biceps femoris muscles and the gluteus superficialis is cut. The nerve is then loosely tied with four chrome gut ligatures so to occlude, but not arrest, blood flow. The wound is sutured, the animal is given 24 hours to recover, and then both hindpaws are tested for pain sensitivity. Sounds terrible, but it’s certainly not the worst of the experiments I researched.

I have no idea what’s going on with the coloring in this. Again, going for feel more than accuracy, but the hues are way too calm.

Information link: https://www.ncbi.nlm.nih.gov/pubmed/22433911

Experiment #5 - Writhing Test

Particularly cruel test in which acetic acid is introduced into the system, inducing severe internal pain. The typical response includes writhing, abdominal retraction, and stretching of the hind limbs. Despite the test being withdrawn in 2004 for unethical reasons, it is still employed by some.

This was my favorite one to draw. Although the lighting and shading are not the greatest, it made for an interesting experiment. I did not intend for the lines to be so bold, but it kind of turned into an almost comic-style illustration. I ended up playing around with it a bit and like the result enough to post it.

I would not watch the video below if you are squeamish. It is difficult to swallow. On another note, you may find the “Empathetic Behavior: Emotional Contagion in Mice” section in the second link of interest. For cage mates in particular, if one or both mice were injected with the same acid, and allowed to observe one another, an injected mouse would writhe more if its partner was also in pain. I can’t help but imagine Brain and Pinky in this type of situation....

Information link #1: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543562/

Information link #2: https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/writhing-test

Video example: https://www.youtube.com/watch?v=Ib63O4F856w

Experiment #6 - Transgenic K5ras Mouse / Nude Mouse (Combination)

Experiment in which cancer is induced in the system. Nude mice are bred for a number of tests, and are used for this one, as well.

My least favorite to draw, but my favorite to color. One particular experiment I found showed a tumor in every follicle on a mouse’s muzzle. Was trying to go for this look, albeit exacerbated.

Information link #1: https://www.cell.com/current-biology/fulltext/S0960-9822(98)70203-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982298702039%3Fshowall%3Dtrue

Information link #2: https://www.motherjones.com/politics/2012/08/weirdest-lab-mice/

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Bonus:

This is based on a test that I found absolutely hilarious. There’s a certain chemical, called W-18, that’s been on the drug market for... some years. The potency of it is supposedly insanely high, although this has never been proven. It’s basically a research chemical (created at a university in the 80s) with analgesic properties that were shown to be “painkillers or blockers of the painkilling effect of morphine in mice”. Mice, not humans. To quote a specific article:

“... when they first injected some of these chemicals into the animals at a dose similar to aspirin, the mice stood up for about a minute and fell over unconscious. They remained unconscious – for five days. But they weren’t dead. They were still breathing. And when they woke, they seemed fine, other than being really hungry and thirsty.”

They literally keeled over from the supposed potency of it. From what I recall, they don’t even know exactly what it was doing to their system, other than the fact that it knocked them out. I just find it funny that they were completely fine after awakening days later.

Although the pure smell of it wouldn’t cause such a reaction, I liked the idea of it in picture form and so depicted Brain simply taking a whiff before passing out.

Information link: https://www.forbes.com/sites/davidkroll/2016/04/30/w-18-the-high-potency-research-chemical-making-news-what-it-is-and-what-it-isnt/#2c45a5dd4757

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Experiments researched, but not implemented:

- Tail dipped in ice cold water (mentioned here: cold water) - Morris water maze - Porton Down nerve agent test(s) (the worst; not even sure how I’d depict this)

The Porton Down tests sounded so indescribably cruel that I simply couldn’t bear to put Brain or Pinky through either of those, much less draw them out. It was the most horrific of the experiments I found, second only to a story about a French physiologist in the 1700s/1800s who performed, I believe, vivisection on live, six-week-old puppies. There’s a limit and that’s my limit. Even the cancer-based composition above was difficult to create. I legit felt dirty drawing it.

Researching these subjects was incredibly interesting, and I came across a few articles that touched on animal experimentation and the question of whether or not it’s ethical. Should such practices continue? It’s more complicated than a simple “yes” or no” answer. Some tests are fairly harmless, whilst others border on the inhumane, and some are downright cruel. Some people say that, without testing, there would be a lot less medicine on the shelves to assist in relieving and curing our ailments, whilst others argue that 90+% of the time the testing done is unnecessary, the results yielded by the subjects dissimilar to those that would be shown by humans and, henceforth, stating that the inaccuracies are numerous. This particular article offered up what I thought was a pretty genuine and interesting debate on the matter:

Pain in Lab Animals: How Much is Too Much?

In an interview with Dr. Jeffrey Mogil, a neuroscientist, he mentions that:

“You have complete control over everything in mice. Within limits, you can do whatever you want as long as you minimize pain and suffering of the subjects.“

Full interview: https://www.integrativepainscienceinstitute.com/latest_podcast/sex-differences-in-pain-and-pain-inhibition-with-dr-jeffrey-mogil/

While many establishments do follow the Animal Welfare Act, other laboratories still implement unethical practices. Also, the rules for what constitutes as acceptable in regards to tests that can only be performed without painkillers or anesthesia administered is... nebulous.

Thankfully, there is a number of lab testing equipment on the market specifically designed to be more humane and less stress-inducing to its subjects. These restrainers, for example, allow the animal to “walk in” without having to be physically forced backwards into a container:

Restrainers

Here is another example of testing that is relatively pain-free:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401362/

It’s simple and inexpensive while still allowing scientists to perform tests.

Below is a video showing how a type of rotarod works, one that doesn’t place the rods too high and provides a cushion underneath in case the subjects fall:

https://www.youtube.com/watch?v=T38fDS2i13k

This tail flick analgesia meter comes installed with a cut off timer to avoid damage to the animal:

https://www.youtube.com/watch?v=JgaStZt143o

So there are options. How often are such options utilized in the field? I have no idea, although there are laws that should be followed and, from the sound of it, generally are adhered to. Not everyone in this business is cruel. Though you do have your occasional psychopath who performs very morally questionable operations behind closed doors, I believe that this is a great exception to the rule, and that there are a lot of laboratory workers who genuinely want to inflict as little pain as possible upon the animal. Just an opinion. I don’t have tons of evidence, but it seems like most people are sane. Lol.

Most of the experiments I inflicted upon Brain because, I think, Pinky is so pure that I have a hard time imagining him sustaining any kind of extreme pain that would genuinely hurt him. Also, he borders on being freakin’ masochistic, finding pleasure in a lot of painful situations, whereas Brain does not. Brain has been through a lot, mentally and physically. It seemed more... “appropriate” to put him in these situations, as terrible as that sounds.

All of that having been said, I never want to do this kind of exercise again. While a lot of it was interesting, and some of it even fun, parts of it were legitimately painful. The cancer one.... I felt horrible....

#pinky and the brain #tw:pain #tw:experimentation #tw:needle #tw:needles #tw:cancer #fan art