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dmsden · 2 years

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Direct Currents - A bit of a news round-up and predictions

Hullo, Gentle Readers. Well, D&D dropped a few surprises our way this week, so I thought I might do another bit of a news round-up. There aren't so many to announce...yet...but there's about to be quite a bit it would seem. Let's jump right in.

First, news came this past week that Wizards of the Coast had purchased D&D Beyond. I'm super intrigued by this news, and I wonder what it will mean for the game's electronic toolset. A lot of people don't seem to have realized that D&D Beyond wasn't produced by WotC already, but it's true. Will this mean that buying a WotC book will give you access to it in D&D Beyond without having to purchase it again? I would love that, personally, but I guess we'll find out! And we might find out sooner than we realized because of the next item...

On April 21, at 12:00 PM Eastern time, Wizards will be hosting the first ever D&D Direct. This is scheduled to run for about 30 minutes, and it promises to reveal all kinds of news about the future of D&D. I've seen crazy amounts of speculation, but I figured I'd toss my two cents in, based on the little preview they put out (which you can watch at https://youtu.be/5A9KrjfUqT8) and thoughts of my own.

The first image we see combines a printed out character sheet (I think it might be the sample Cleric character from the original Starter Set) next to a tablet displaying the stats of an Ancient Red Dragon. I guess it's possible they'd announce a new Starter Set, perhaps incorporating the changes they've told us to expect, but given that version 5.5 isn't supposed to be here until 2024 for the 50th anniversary, I'd say that's unlikely. I suspect the tablet represents the fact that we'll likely get some news on how D&D Beyond will integrate with the rest of WotC's plans.

This is followed by a pan over a map with miniatures, including a Beholder. We see a chibi mind flayer, and then a dice tower with some rather nice looking dice rolling out of it. I believe I saw something about some new chibi D&D collectibles coming. Maybe there is more info to come on them. The red dice make me think about collectible dice, but the Ruby Anniversary would've been for the 40th year, so not sure there.

The next big item is a movie script for “Untitled D&D Movie” by Jonathan Goldstein & John Francis Daley. Given that they are both the writers and directors of the upcoming D&D movie slated for release in March 2023, I think it's safe to say we're going to hear something about this. We then see the Beholder and the Mind Flayer again. Given what iconic D&D monsters these are, and both so intrinsically tied to the Underdark, I suspect this means that either:

a. The movie will feature these monsters as major adversaries.

b. An upcoming adventure campaign or sourcebook will focus on the Underdark. After all, we had Rage of Demons and the Out of the Abyss module, but these were about the Demon Princes changing the Underdark more than they were about the Underdark as it normally is. I'd love to see an update/remake of the classic Night Below campaign.

The camera pans over what I'm fairly certain is an Xbox controller before pausing on a plush of a hamster holding a D20. Now, the controller is pretty easy. We know Baldur's Gate III is still in early release, and there's an untitled 3rd person game coming. I assume we'll get some news about one or both.

For the hamster, it's pretty obviously a nod to Boo, Miniature Giant Space Hamster companion of the ranger Minsc. This could be a Baldur's Gate reference as well, but...well...there are two things that make me wonder if it doesn't mean something else.

A few months back, an Unearthed Arcana article was released that included a number of Spelljammer-centric races. Then, on April 1, a small image of the same hamster plush spinning through space was put up on WotC's Twitter account with the phrase Spelljammer Confirmed. Most people assumed it was just a joke, but...what if it weren't? The Spelljammer Confirmed has become such an in-joke of WotC's Twitter feed, that this could be a kind of double-blind situation, where they're telling the truth, hiding it in plain sight. I hope that's what it is, because I'd love to see what a new generation of writers does with that material. I always had a huge fondness for it.

We pan briefly over a large mini of a red dragon, very similar to the illustration we saw on the tablet. I'm pretty sure this is one of WizKids' already released ones, so it seems likely it's just set decoration. Finally, we see the title card showing the date of the Direct.

So much potential for exciting stuff! We'll have to wait a bit to see what's coming, but not very long at all. And then you'll know if I'm clever or just utterly wrong and clueless. Until then, let's hope that the Eyes of the Beholder are turned the other way!

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dcmultiverse · 5 years

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Development for The Flash has long been stuck in slow-motion, but the Scarlet Speedster is once again at the starting block, and this time seems ready to catch-up to his fellow Justice Leaguers, courtesy of a new director and screenwriter. Today The Hollywood Reporter broke the news that It-helmer Andy Muschietti will direct The Flash, taking over for John Francis Daley and Jonathan Goldstein. Christina Hodson (Bumblebee, Birds of Prey) will write the new script, using neither Daley and Goldstein’s drafts nor the script Grant Morrison co-wrote with star Ezra Miller. Muschietti is now the fourth director to join the DC film from Warner Bros. and New Line’s successful stable of filmmakers. Like Aquaman's James Wan and Shazam!'s David Sandberg, and Black Adam's Jaume Collet-Sera, Muschietti has the unique opportunity to inject the skills acquired within the horror genre into the world of superheroes.

#m: the flash #the flash #movie #news

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superdorkcat · 5 years

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DCEU Movies in Development: A Master Post

Last Edited: May 01, 2019

Since Shazam! is coming out soon, I thought I’d make a master post of all the various DCEU movies in development. However, since there’s a huge amount of movies in development, I might miss one or two. Be sure to let me know if I do.

Also, as a side-note, I broke Birds of Prey and Wonder Woman 1984 into three segments of story, crew, and cast, but since things are less clear in regards to The Batman, The Suicide Squad, and Aquaman 2, I wasn’t able to do the same for them.

Confirmed Release Dates:

Birds of Prey (and the Fantabulous Emancipation of One Harley Quinn) - February 7, 2020

The Story: Since the events of Suicide Squad, Batman has disappeared, leaving Gotham City unprotected from crime, and Harley Quinn has left the Joker. When Cassandra Cain, a young girl, comes across a diamond belonging to crime lord Black Mask, Harley joins forces with Black Canary, Huntress, and Renee Montoya to help protect her.

The Crew: Cathy Yan (director), Margot Robbie, Sue Kroll, Bryan Unkeless (producers), Christina Hodson (screenwriter), Matthew Libatique (cinematographer)

The Cast: Margot Robbie (Harley Quinn), Jurnee Smollett-Bell (Black Canary), Mary Elizabeth Winstead (Huntress), Rosie Perez (Renee Montoya), Ella Jay Basco (Cassandra Cain), Ewan McGregor (Black Mask), Chris Messina (Victor Zsasz)

Wonder Woman 1984 - June 5, 2020

The Story: Diana Prince comes into conflict with the Soviet Union during the Cold War in the 1980s, and finds a formidable foe in the form of the Cheetah.

The Crew: Patty Jenkins (director), Charles Roven, Deborah Snyder, Patty Jenkins, Stephen Jones, Gal Gadot (producers), Patty Jenkins, Geoff Johns, David Callaham (screenwriters), Patty Jenkins, Geoff Johns (writers), Hans Zimmer (composer), Matthew Jensen (cinematographer), and Richard Pearson (editor)

The Cast: Gal Gadot (Wonder Woman), Chris Pine (Steve Trevor), Kristen Wiig (Cheetah), Pedro Pascal (TBA), Connie Nielsen (Hippolyta), Robin Wright (Antiope)

The Batman - June 25, 2021

In October 2014, a Batman standalone film was announced by Warner Bros. By 2016, Ben Affleck was set to star in, produce, direct, and write the project. Geoff Johns and Chris Terrio were hired as co-writers. After various drafts of the script had been completed the film was moving towards beginning shooting by 2017, until Affleck stepped down as director that January. Affleck initially cited his intentions being to more specifically focus on starring as Batman, later acknowledging that after various attempts to get the script where he wanted it, it simply became "time to let someone else have a shot at it". In July 2017, Matt Reeves confirmed that the script was being rewritten: the final draft was completed by January 2019. Reeves reworked the story to focus on Batman earlier on in his career as a vigilante; he said the film will be character-driven and stylistically noir, and will explore the detective aspect of the character to a greater extent than previous films. In January 2019, Affleck confirmed he will not reprise his role as Batman, but remains involved as a producer. Principal photography is expected to begin in November 2019.

The Suicide Squad - August 6, 2021

In March 2016, a Suicide Squad sequel was announced to be in development, with David Ayer returning to direct. Adam Cozad was hired to write the script by March 2017. By July 2017, a new story treatment was written by Zak Penn. In September, Gavin O'Connor was hired as director after Ayer dropped out, as well as co-screenwriter with Anthony Tambakis, David Bar Katz and Todd Stashwick. The final draft of the script was completed in October 2018, though production was delayed due to conflicts with Will Smith's production schedule, followed by O'Connor leaving the project. Production was placed on hold as Warner Bros. believed the script was too similar to Birds of Prey. Charles Roven, Michael De Luca, Peter Safran, Geoff Johns, Richard Suckle, Dan Lin and Andy Horwitz will produce the film. In January 2019, the film was retitled The Suicide Squad, with James Gunn directing, from a new script he wrote. Gunn chose the project over various other films Warner Bros. has in development, including the Man of Steel sequel. In March, Idris Elba joined the cast. He was initially going to replace Smith, who dropped out due to scheduling conflicts, as Deadshot, but it was later decided that Elba would play a new character so Smith could return in the future. Margot Robbie, Joel Kinnaman, Jai Courtney, and Viola Davis will reprise their roles as Harley Quinn, Rick Flag, Captain Boomerang, and Amanda Waller, respectively. David Dastmalchian and Daniela Melchior were cast to portray Polka-Dot Man and Ratcatcher, respectively. John Cena is in talks to portray an as-of-yet unnamed role. Other members of the titular team include King Shark and Peacemaker. Production will begin in September 2019

Aquaman 2 - December 16, 2022

By December 2018, a sequel to Aquaman was in development. In October 2018, James Wan stated the first film intentionally left room for a follow up. Jason Momoa later revealed that he had an idea for the sequel, and had written the first act. The actor pitched the story to Warner Bros. through Toby Emmerich and producer Peter Safran, who were receptive. By December, high pre-release ticket sales and positive reception for the film had convinced Warner Bros. to begin developing a sequel. In January 2019, Warner Bros. confirmed development, with intentions for Wan to return as director. The following month, David Leslie Johnson-McGoldrick, co-writer of the first film, signed on as screenwriter. In March, Safran announced the film will explore the other Seven Kingdoms of Atlantis.

Unknown Release Dates:

The Flash

By July 2013, Greg Berlanti was developing a film that centered around the Barry Allen incarnation of the Flash. In October 2014, The Flash was announced with a scheduled 2018 release date. The initial script was drafted by Berlanti, Chris Brancato, Michael Green and Marc Guggenheim. In April 2015, a story treatment was written by Phil Lord and Christopher Miller based on the previous draft, with the intention being that the duo would also direct the film. Over the next two years, Seth Grahame-Smith and Rick Famuyiwa, had individually dropped out as directors of the project due to creative differences with the studio. In January 2017, Joby Harold was hired to do a page-one rewrite of the script, which previously had drafts written by Grahame-Smith and Famuyiwa. In July 2017, the title for the film was changed to Flashpoint, based on the comic book story arc of the same name. In March 2018, John Francis Daley and Jonathan Goldstein were hired to co-direct. Zack Snyder, Alex Gartner, Geoff Johns, Dan Mazer, Richard Suckle, Deborah Snyder, Phil Lord, Chris Miller, Jon Berg, Denise Di Novi, and Michael Disco will serve as producers on the project. Dan Mazeau was brought on as co-writer, followed by Grahame-Smith and Brancato as additional screenwriters. The directors had initially announced the release of The Flash to be sometime during 2020, though production was delayed from April 2019 to later in the year for additional script work. By February 2019, Daley and Goldstein had contributed to the script with the film's star revealing that the plot will involve the Speed Force multiverse. Principal photography is scheduled take place in Atlanta, Georgia, and follow in Leavesden, Hertfordshire, England. In March, Ezra Miller was hired to co-write a new draft in a collaboration with Grant Morrison. The tone of the film is expected to be similar to Back to the Future. The Flash is on track to release in 2021.

Lobo

In September 2009, Warner Bros. announced that Guy Ritchie would direct a live-action adaptation. Variety described the premise: "Lobo is a seven-foot tall, blue-skinned, indestructible and heavily muscled antihero who drives a pimped out motorcycle, and lands on Earth in search of four fugitives who are bent on wreaking havoc. Lobo teams with a small town teenage girl to stop the creatures." Ritchie was scheduled to begin production of Lobo in early 2010 and bring an "irreverent, gruff tone" to the film as he did with previous films Lock, Stock and Two Smoking Barrels and Snatch, though the studio was reportedly aiming for a PG-13 rating from the Motion Picture Association of America. In early 2010, it was reported that Ritchie had left the project in order to pursue working on a sequel to his hit film Sherlock Holmes instead. The future of the movie was then put on hold. In 2012, Deadline reported that Brad Peyton would write and direct the film. In July 2012, Dwayne Johnson announced via Twitter that he was in talks with Joel Silver and Brad Peyton to portray Lobo, however on in February of the following year, Johnson left the project to play another villain from the DC Comics, Black Adam, in Shazam!. In March 2016, it was reported that Jason Fuchs will be writing the film's script. As of February 2018, DC Films is eying Michael Bay to direct the film inspired by the success of Tim Miller's Deadpool film. Fuchs is currently rewriting the script at Bay’s request so that the script can be lowered to under to under $200 million.

Justice League Dark

Rumors in November 2012 suggested that Guillermo del Toro was working on a Justice League Dark film titled Heaven Sent. It would feature Deadman, the Spectre, Swamp Thing, John Constantine, Phantom Stranger, Zatanna, Zatara, Sargon the Sorcerer, and Etrigan the Demon. Del Toro later confirmed in January 2013 that he was working on such a film, with the working title, Dark Universe, and was hiring a screenwriter. Del Toro revealed Swamp Thing, Constantine, The Spectre, Deadman, Zatanna and Zatara were characters in the story.

In March 2013, del Toro gave an update on the film at WonderCon 2013, while talking about his film Pacific Rim. He revealed that the story bible was complete and he hoped to start the screenplay soon. Production would begin after his next project, Crimson Peak. The film's story would center around John Constantine recruiting Swamp Thing, Etrigan the Demon, Deadman, Spectre, and Zatanna. The film would not be an origin story, with each character already established and elements of their backstory coming into play throughout the film. Del Toro also revealed that Floronic Man would be in the film. In May 2013, del Toro revealed that his script featured Constantine, Swamp Thing, Madame Xanadu, Deadman and Zatanna as the team, with others "in the mix". He also revealed that he was still waiting for the go-ahead from Warner Bros. Pictures. Del Toro revealed in July 2013 that he hoped that the DC Extended Universe, which started with Man of Steel, would become as cohesive as the Marvel Cinematic Universe, and he added that if there was any correlation to that universe and this film, he would honor it.

In October 2013, del Toro stated he felt his film would be able to coexist with the television series, Constantine and reiterated that the film was still active and in the writing process. In July 2014, del Toro once again stated he was working on the film, and stated it would be independent from the universe established with Man of Steel, saying, "DC and Warners have been very clear that they are trying to keep [this film and Sandman] separate so when the time comes they can unite them, once they know they’re quantifiable." Del Toro also added that his Constantine would not adhere to the continuity established in the television series, but he would consider incorporating elements from it, and even think about casting the same actor (Matt Ryan). In November 2014, del Toro confirmed that the script was complete and handed it in to Warner Bros. to be reviewed. In December 2014, he hinted that the film would be part of the DC Extended Universe.

In April 2015, del Toro said the script revision has been handed in and if there was availability in his schedule, he would direct it; if not, "somebody else will do it... [The film] needs to fall into the plan of the shared universe." In June 2015, the film was confirmed to still be in development at Warner Bros., with some of their other Vertigo Comics film adaptations moving to New Line Cinema. The Hollywood Reporter stated that del Toro was no longer attached to the project. In July 2016, Swamp Thing test footage was released directed by Joseph Kahn. In August 2016, it was announced that Doug Liman would direct the film with del Toro and Scott Rudin producing and Michael Gilio writing, with the film being titled Dark Universe. By May 2017, Liman left the film to focus on directing Chaos Walking. At the San Diego Comic-Con in July 2017, the film's title was announced to be Justice League Dark. By August 2017, Gerard Johnstone was hired to polish the script.

Black Adam

In September 2014, after being considered to play Shazam and Lobo, Dwayne Johnson was cast to play Black Adam in the DCEU. The character was intended to be introduced in Shazam!, but by January 2017 the film's production studios had chosen to divide the narrative to focus on Black Adam's origin. Johnson, who is also attached as producer, has stated the two characters will cross paths in a future film, while other DC characters will make appearances in Black Adam. In October, Adam Sztykiel was hired to write the script. Co-producer Hiram Garcia stated the film will be gritty and violent, similar to the comics. By February 2019, the script was nearly finished with Warner Bros. and Seven Bucks Productions searching for a director. The plot will involve the Carter Hall version of Hawkman, Atom Smasher, and Stargirl. Principal photography is scheduled to begin sometime between late 2019 and early 2020.

Justice League sequel

In October 2014, Justice League Part Two was announced, with Zack Snyder returning as director. In June 2016, Deborah Snyder revealed that Justice League would not be one film split in two, leaving the sequel untitled. The film was scheduled to be released on June 14, 2019, but production was pushed back to accommodate The Batman. In October 2017, J. K. Simmons stated that work on the script was in-progress, while in December, Variety reported that there were "no immediate plans" for Snyder to direct. By 2019, Warner Bros. had prioritized standalone films over the project, although Patty Jenkins noted she would be open to directing the next Justice League film. Though Ben Affleck will not play Batman in Matt Reeves' film, he is still signed on to reprise the role for the Justice League sequel.

Green Lantern Corps

A film based on the Green Lantern Corps was announced to be in development in October 2014. In January 2017, David S. Goyer and Justin Rhodes were hired to co-write the screenplay, based on a story by Goyer and Geoff Johns, with Goyer also serving as producer. Warner Bros. described the film as "Lethal Weapon in space". In January 2018, Goyer reaffirmed that despite the franchise's leadership shakeup the film was still in active development. By June 2018, Geoff Johns was hired to do a rewrite on the script, in addition to his role as producer. Johns stated that the script draws inspiration from his work on the New 52 Green Lantern comics. Green Lantern Corps was scheduled for release on July 24, 2020, but is believed to have been delayed.

Man of Steel sequel

In August 2016, The Wrap reported that Warner Bros. put the film in active development as a top priority. The news of a stand-alone Superman film were later confirmed by Dany Garcia, Henry Cavill's manager. While promoting Arrival, Amy Adams confirmed that work had begun on the screenplay. In March 2017, it was announced that Matthew Vaughn was being eyed by Warner Bros. to direct. In April 2018, it was reported that Christopher McQuarrie is considering directing the film but later dropped it. In June 2018, Cavill revealed that he is preparing to reprise the role.

Booster Gold

In September 2015, a film centered around Booster Gold and the Ted Kord Blue Beetle was announced to be in development with producer Greg Berlanti. The film's tone was described as a buddy cop film with connections to Justice League. By May 2016, Zak Penn had begun work on a script. Berlanti stated that the project had "no connective tissue" to other films at one point, but following a consideration for television series adaptation at Syfy, the project entered a script rewrite from Zack Stentz in May 2016. Berlanti was asked about his involvement with the DCEU as a whole, and indicated that he has interest in the Booster Gold film. After years of being involved in the project's development, Berlanti was reported to be in negotiations with the studio to serve as director. By March 2018, the script, co-written by Berlanti, had been completed. Berlanti stated production would begin once Warner Bros. decides where to place it within the slate of films.

Gotham City Sirens

A film based on the Gotham City Sirens, a team consisting of Harley Quinn, Catwoman, and Poison Ivy, was announced to be in development in December 2016. David Ayer signed on as director/co-producer from a script by Geneva Robertson-Dworet, Margot Robbie will reprise her role from Suicide Squad and take the role of an executive producer, while Geoff Johns and Jon Berg will produce. Production was originally scheduled to begin in mid-2017, but following the restructuring of DC Films leadership the film's development was placed on hold in favor of Birds of Prey. In August 2017, Jared Leto was confirmed to reprise his role as the Joker. Despite a busy production schedule on other projects, Ayer has continued to work on the film, meeting with Gotham City Sirens creator Paul Dini in August 2018.

Deadshot

In December 2016, The Hollywood Reporter noted that a film centered around Deadshot was in development. By September 2018, Will Smith confirmed he would reprise his role from Suicide Squad and that the story is in development.

Nightwing

On February 23, 2017, it was reported that Warner Bros. Pictures was developing a Nightwing live action movie centered on the character, set in the DC Extended Universe, with Bill Dubuque writing the script and The LEGO Batman Movie director Chris McKay signed on to direct the movie.

Discussing why he likes the character and signed on for the project, McKay cited the character's showman personality and background as an entertainer and expressed his excitement for depicting that in the film. He later stated that he wants to introduce a complete adaptation of the character, something that hasn't been done in previous film interpretations of him before. McKay continued to state that the director-driven approach is why he loves Warner Bros., and how the franchise is differentiating itself from other popular shared universes. In an interview with Cinemablend, McKay confirmed that the film would acknowledge the titular character's past from the source material, including his time as a part of Haly's Circus, and also reaffirmed that the film will be a straightforward action movie with minimal use of CGI special effects and grounded realism.

In February 2018, McKay stated the script was nearing its final draft.

Batgirl

In March 2017, it was announced that Joss Whedon was in talks to write, direct and produce a Batgirl film as part of the DC Extended Universe. The film will feature the Barbara Gordon incarnation of the character, with The New 52 comics by Gail Simone serving as "a starting point" for the film. In April 2017, Whedon stated that he was fascinated by a character that chooses to be a vigilante, even though she hadn't suffered any tragedies in her life like Batman, and that the damaged aspect of the character will be explored in the film. In July, Geoff Johns stated production on the film would begin in 2018. At San Diego Comic Con 2017, the title was announced to be Batgirl.

Whedon was to begin production on the film in 2018, but stepped down in February 2018. In April 2018, after impressing the studio with her work on Birds of Prey, Christina Hodson was hired as screenwriter for Batgirl as well. The studio is actively looking for a female director.

Deathstroke

In October 2017, TheWrap reported a film centered around Deathstroke was in development, with Gareth Evans attached as screenwriter and director and Joe Manganiello set to reprise his role from Justice League. Ben Affleck released test footage with Manganiello in costume in August 2016. Warner Bros. greenlit the film after Evans impressed executives with his story pitch, which he described as dark and unforgiving, similar to Korean noir films. However, in October 2018, Evans stated that he is yet to be attached to the project contractually.

New Gods

By March 2018, a film about the New Gods was confirmed to be in development, with Ava DuVernay signed on as director. Kario Salem was hired as screenwriter after working on a story treatment with DuVernay.

Supergirl

In August 2018, a film centered on Supergirl, was announced to be in development with Oren Uziel penning the script. Warner Bros. is seeking a female director, with Reed Morano—who has expressed interest in the project—being its top choice.

Blue Beetle

By November 2018, a film centered around the Jaime Reyes incarnation of Blue Beetle was in development. Gareth Dunnet-Alcocer and Zev Foreman are respectively attached as screenwriter and executive producer.

Plastic Man

By December 2018, a Plastic Man film was in development with Amanda Idoko hired to write the script. The plot is described as a comedy-action adventure.

Wonder Woman 1984 sequel

In January 2019, after principal photography on Wonder Woman 1984 was completed, director and co-writer Patty Jenkins stated the plot for a third Wonder Woman film had been mapped out. She revealed that the story arc for Wonder Woman had been planned over three films, with the third taking place in the present.

The Trench

In February 2019, Warner Bros. announced a horror spin-off from Aquaman focusing on the villainous Trench kingdom. Peter Safran and James Wan are set to produce, with Noah Gardner and Aidan Fitzgerald acting as screenwriters. The film is expected to have a lower production budget compared to other DC-based films. The following month, Safran said he expects the film to be released before Aquaman 2.

Blackhawk

In April 2018, it was announced that Steven Spielberg will produce/direct a film adaptation of Blackhawk for Warner Bros., with the screenplay being written by David Koepp. Spielberg will co-produce the film with Kristie Macosko Krieger and Sue Kroll.

Shazam! sequel

Following the success of Shazam!, in April 2019 a sequel was announced. Henry Gayden is returning as screenwriter, while David F. Sanberg and Peter Safran are expected to reprise their duties as director and producer, respectively. Mark Strong will reprise his role as Dr. Sivana. Michelle Borth confirmed she will reprise her role as Lady Shazam, as part of a five-picture Warner Bros. contract.

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angleonmovieon · 3 years

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Dungeons & Dragons Reboot Begins Filming – Dungeons & Dragons movie has officially begun filming. Based on the popular tabletop role-playing game of the same name, Dungeons & Dragons has been adapted several times before. The reboot was announced in 2013 by Warner Bros. – #DungeonsDragons cast Chris Pine in a lead role and it's only been uphill from there. A slew of big names have been revealed to be attached to the film, including Bridgerton breakout Regé Jean-Page, Fast & Furious franchise mainstay Michelle Rodriguez, and rising star Sophia Lillis. In addition, Hugh Grant is onboard as Dungeons & Dragons' villain. – Director Jonathan Goldstein announced on Twitter that production had begun on the film. The tweet is accompanied by a picture of a clapboard with the Dungeons & Dragons logo across the top. John Francis Daley, Goldstein's co-director, is also listed on the clapboard. Goldstein kept the caption simple, announcing The campaign begins. https://www.instagram.com/p/COZ9nCSnAcH/?igshid=1gwuebng9zm2q

#dungeonsdragons

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blackdieselcinema · 5 years

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Black Diesel CineFest VIII

Over the weekend, I hosted the eighth annual Black Diesel CineFest. Here’s the line-up in full, plus the playlist for my 15th anniversary DJ set on Saturday night (as per usual, all movies – and trailers - were kept a complete secret from the audience until the opening credits rolled):

Saturday

Trailers: Star Wars: The Rise of Skywalker, Brightburn, Godzilla: King of the Monsters.

Feature: THE HIDDEN (Jack Sholder, 1987)

Trailers: Her Smell, Dolor y Gloria, Once Upon a Time in Hollywood.

Feature: THE GIRL CAN’T HELP IT (Frank Tashlin, 1956)

Trailers: Ash is Purest White, The Art of Self Defense, Detective Pikachu.

Feature: MAD DETECTIVE (Johnnie To, Wai Ka-fai, 2007)

Trailers: Parasite, The Beach Bum, The Dead Don’t Die.

Feature: ONE CUT OF THE DEAD (Shinichirou Ueda, 2017)

Trailers: Someone Great, Booksmart.

Bonus: Connor4Real: “Fuck Off” (‘Popstar’ deleted scene)

Feature: GAME NIGHT (John Francis Daley, Jonathan Goldstein, 2018)

Sunday

Trailers: Ma, Starfish, Midsommar.

Feature: ROAD GAMES (Richard Franklin, 1981)

Trailers: Asako I & II, Long Day’s Journey Into Night, John Wick: Chapter 3 - Parabellum.

Feature: CHINA GIRL (Abel Ferrara, 1987)

Trailers: Eighth Grade, Spider-Man: Far From Home.

Feature: THE PRINCESS AND THE FROG (Ron Clements, John Musker, 2009)

Trailers: Joker, High Life, Avengers: Endgame.

Feature: UPGRADE (Leigh Whannell, 2018)

Trailers: Dragged Across Concrete, Little Woods, Too Old To Die Young.

Feature: BOUND (Lana Wachowski, Lilly Wachowski, 1996)

My 15th Anniversary DJ Set

A HUGE thank you to everyone that attended.

Cheers, Andrew

Follow me on Twitter @blackdieseluk

Check out last year’s line-up here.

#black diesel cinefest #film #movies #cinema #film festival

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badlands75 · 4 years

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Badlands75RT @JohnFDaley: Anybody gonna chime in on how we stop Trump from suppressing the vote?

Anybody gonna chime in on how we stop Trump from suppressing the vote?

— John Francis Daley (@JohnFDaley) August 13, 2020

from Twitter https://twitter.com/Badlands75 August 13, 2020 at 03:52PM via IFTTT

#IFTTT #Twitter

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biofunmy · 5 years

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Nobel Prize in Medicine Awarded for Research on How Cells Manage Oxygen

The Nobel Prize in Physiology or Medicine was jointly awarded to three scientists — William G. Kaelin Jr., Peter J. Ratcliffe and Gregg L. Semenza — for their work on how cells sense and adapt to oxygen availability.

The Nobel Assembly announced the prize at the Karolinska Institute in Stockholm on Monday.

Their work established the genetic mechanisms that allow cells to respond to changes in oxygen levels. The findings have implications for treating a variety of diseases, including cancer, anemia, heart attacks and strokes.

Why did they win?

“Oxygen is the lifeblood of living organisms,” said Dr. George Daley, dean of Harvard Medical School. “Without oxygen, cells can’t survive.” But too much or too little oxygen also can be deadly. The three researchers tried to answer this question: How do cells regulate their responses?

The investigators uncovered detailed genetic responses to changing oxygen levels that allow cells in the bodies of humans and other animals sense and respond to fluctuations, increasing and decreasing how much oxygen they receive.

Why is the work important?

The discoveries reveal the cellular mechanisms that control such things as adaptation to high altitudes and how cancer cells manage to hijack oxygen. Randall Johnson, a member of the Nobel Assembly, described the work as a “textbook discovery” and said it would be something students would start learning at the most basic levels of biology education.

“This is a basic aspect of how a cell works, and I think from that standpoint alone it’s a very exciting thing,” Mr. Johnson said.

The research also has implications for treating various diseases in which oxygen is in short supply — including anemia, heart attacks and strokes — as well as for treatment of cancers that are fed by and seek out oxygen.

Who are the winners?

William G. Kaelin Jr., professor of medicine at Dana-Farber Cancer Institute and Brigham & Women’s Hospital Harvard Medical School, was drawn to science for its objectivity.

“Like any scientist, I like solving puzzles,” he said in an interview this morning.

But he had an unprepossessing start. When he was a pre-med student hoping to become a physician researcher, a professor wrote, “Mr. Kaelin appears to be a bright young man whose future lies outside of the laboratory.”

Eventually he became intrigued by a rare, genetic cancer, von Hippel-Lindau disease, that is characterized by a profusion of extra blood vessels and overproduction of erythropoietin, or EPO, a hormone that stimulates production of the red blood cells that carry oxygen.

The cancer “was really fascinating,” Dr. Kaelin said. It had unusual features, like causing the body to make a substance, vegF, that stimulates the formation of blood vessels. And the cancer can cause the body to make too many red blood cells by increasing the production of EPO.

He had a hunch about what was going awry: “I thought it had something to do with oxygen sensing.”

As it turned out, he was right.

“It is one of the great stories of biomedical science,” Dr. Daley said. “Bill is the consummate physician-scientist. He took a clinical problem and through incredibly rigorous science figured it out.”

Dr. Kaelin said he knew, of course, that today the Nobel Prize would be awarded. But his chances were “so astronomically small” that he stuck with this usual routine and did not stay up last night.

He had a dream, though, that he had not gotten the 5 a.m. call from Sweden. He woke up and looked at the time; in fact, it was just 1:30 a.m.

He went back to sleep, and when it really was 5 a.m., his phone rang.

Gregg L. Semenza, professor of genetic medicine at Johns Hopkins, said his life was changed by a high school teacher, Rose Nelson, who taught biology at Sleepy Hollow High School in Sleepy Hollow, N.Y.

“She was unbelievable,” Dr. Semenza recalled in an interview. “She transmitted the wonder and joy of science and scientific discovery. She set me on a course to science.”

In college, at Harvard, he thought he would get a Ph.D. and do research in genetics. But then a family he was close to had a child with Down syndrome.

“That shifted me from being interested in genetics as kind of a scientific discipline to thinking about the impacts of genetics on people,” he said.

After attending medical school at the University of Pennsylvania, Dr. Semenza set out to understand what cancer cells are searching for when they spread into surrounding tissues, and then into blood vessels that carry them around the body.

His guess was that cancer cells are searching for oxygen.

Dr. Semenza turned his attention to the gene the guides production of EPO. Once it is activated, the body makes more oxygen carrying red blood cells. But how is that switch turned on when the body is deprived of oxygen?

As a geneticist, he was trained to study rare genetic diseases. But his work on cellular responses to oxygen led him to study such common diseases as heart disease and cancer.

At first, he divided his attention between the two conditions. More recently, Dr. Semenza said, he has focused on cancer, looking for ways to use what he has learned to find new ways to attack tumors.

Dr. Semenza was asleep when the call from Sweden came this morning, and did not get to his phone in time to answer it. The phone rang again a few minutes later.

“I heard this very distinguished gentleman tell me I was going to receive the Nobel Prize,” he said. “I was shocked, of course. And I was kind of in a daze. I’ve been in a daze ever since.”

But he added, “It’s been wonderful.”

Peter J. Ratcliffe, the third Nobelist, is the director of clinical research at the Francis Crick Institute in London and director of the Target Discovery Institute at Oxford.

He became a medical researcher almost by chance. “I was a tolerable schoolboy chemist and intent on a career in industrial chemistry,” he said in a speech in 2016. “The ethereal but formidable headmaster appeared one morning in the chemistry classroom. ‘Peter,’ he said with unnerving serenity, ‘I think you should study medicine’. And without further thought, my university application forms were changed.”

He became a kidney specialist, fascinated by the way the organs regulate production of EPO in response to the amount of oxygen available. Some colleagues, he said, felt this was not very important.

But he persisted, intrigued by the scientific puzzle. “We set about the problem of EPO regulation, which might have been seen, and some did see, as a niche area,” he said in a telephone interview posted by the Nobel Committee on Twitter.

“But I believed it was tractable, it could be solved by someone. The impact of that became evident later.”

The research is an illustration of the value of basic research, he added: “We make knowledge, That’s what I do as a publicly funded scientist. It is good knowledge. It is true. It is correct.”

But, he added, “We set out on a journey without a clear understanding of the value of that knowledge.”

When the call from Sweden came, Dr. Ratcliffe was writing a grant proposal. Today he will continue working on it.

“I’m happy about it,” he said of the Nobel Prize. But also was not enthusiastic about being thrust into the public eye.

“I’ll do my duty, I hope,” he said.

“It’s a tribute to the lab, to those who helped me set it up and worked with me on the project over the years, to many others in the field, and not least to my family for their forbearance of all the up and downs,” he said in a statement released by Oxford.

Who won the 2018 Nobel for medicine?

The prize last year went to James P. Allison of the United States and Tasuku Honjo of Japan for their work on immunotherapy, for unleashing the body’s immune system to attack cancer. This breakthrough has resulted in an entirely new class of drugs and brought lasting remissions to many patients who had run out of options.

Who else won a Nobel Prize this year?

The 2019 Nobel Prize in Physics was awarded to James Peebles, Michel Mayor and Didier Queloz for their contributions to the understanding of the evolution of the universe and Earth’s place in the cosmos.

The prize for chemistry was shared by John B. Goodenough, M. Stanley Whittingham and Akira Yoshino for their work on the development of lithium-ion batteries.

When will the other Nobel Prizes be announced?

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Michael Wolgelenter contributed reporting.

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