#Hypoparathyroidism Drug Market forecast

[healthcaremarketfmi]

Transformative Innovations and Competitive Landscape in the Hypoparathyroidism Treatment Market: Insights and Forecast for the Next Decade

Hypoparathyroidism is a rare endocrine disorder, which often results in levels of calcium and high levels of phosphate, which in turn results in the production of low or abnormal parathyroid (PTH) levels. According to a recent research report by Future Market Insights (FMI), the hypoparathyroidism treatment market is estimated to reach a valuation of US$ 717.7 Mn in 2021, and is projected to display a promising CAGR of approximately 8% through the end of the forecast period in 2031.

Hypothyroidism primarily arises from surgeries in the neck region. It is associated to accidental damage to the parathyroid gland. High prevalence of these surgeries is expected to boost the demand in the hypoparathyroidism treatment market. For instance, in the U.S., up to 115,000 people are diagnosed with the chronic hypoparathyroidism. The majority of the hypoparathyroidism cases are caused by anterior neck surgery, which accounts for up to 75% of the of all hypoparathyroidism cases. The remaining 25% cases are non-surgical or in very rare cases is linked to genetic disorders.

Furthermore, considering the rare occurrence of this medical condition, hypoparathyroidism has been designated as an orphan disease by the U.S. FDA and European Commission. This designation of orphan disease will help manufacturers to speed up their drug development processes, which leads to better availability of drugs for treatments of hypoparathyroidism.

However, the unprecedented nature of the COVID-19 pandemic has had a significant impact on the development of drugs for rare diseases including those associated with hypoparathyroidism.  Preference now is being given to the development of life-savings drugs with greater focus on development of COVID-19 drugs and vaccines, thus halting or suspending existing clinical trials other than live saving drugs.

Also, this has led to the delay or postponement of enrolment of the new participants for clinical studies. Thus, the lack of sufficient data availability on the safety and effectiveness of treatments from clinical trials, will hurt short-term prospects. Clinical trials will gradually resume through 2021, and is anticipated to pick up pace during the forecast period.

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Key Takeaways from Hypoparathyroidism Treatment Marker Study

Calcium supplements dominate the hypoparathyroidism treatment market growing 2x by 2031 owing to efficacy with hormonal therapy.

Parenteral route of administration is projected to grow at higher pace, driven by a rise in the number of clinical trials, and approval of new drugs which are influencing strong growth in this segment.

United States holds over 85% of the North America market for hypoparathyroidism treatments and will remain dominant owing to government incentives.

The U.K. will exhibit high demand, registering y-o-y growth at nearly 7% in 2021.

Germany and France will emerge as key markets within Europe.

China and India reflect high potential for growth on the back of a large subclinical patient pool for kidney disorders, diabetes, obesity, thyroid surgeries or head & neck surgery.

Growing cases of hypoparathyroidism and associated neck surgeries, coupled with an increase in patient awareness and screening, faster approvals and grants for product development, and favorable reimbursement scenarios, are major factors influencing market growth. Demand for biologics and the emergence of personalized medicine are some of the upcoming trends that are expected to generate significant growth opportunities for manufacturers operating in this space,” says the FMI Analyst

Product Approvals, and Expansion Strategies Gain the Focus of Drug Manufacturers

Prominent players in the hypoparathyroidism treatment market are focusing on receiving approvals and grants for the development of new drugs to cater to the growing cases of hypoparathyroidism, thus, enhancing their market presence. For instance,

In October 2020, Ascendis’s TransCon PTH was designated as orphan drug by the European commission (EC), which is approved for use to treat hypoparathyroidism in Europe.

In July 2020, ProLynx, received a Small Business Innovation Research (SIBR) grant from NIH to help fasten the development PTH (1, 34), a long acting parathyroid hormone that can be in a week to patients suffering from hypoparathyroidism.

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Hypoparathyroidism Drug Market - Industry Trends - Forecast to 2026

Global hypoparathyroidism drug market is expected to grow at a substantial growth of 8.1% CAGR in the forecast period of 2019-2026. The emergence of drugs used in thyroid diseases, increases number of   thyroid cancer, development of newer technologies and vulnerable hypoparathyroidism patients enhancing the market growth.

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#Hypoparathyroidism Drug Market #Hypoparathyroidism Drug Market share #Hypoparathyroidism Drug Market news #Hypoparathyroidism Drug Market report #Hypoparathyroidism Drug Market growth #Hypoparathyroidism Drug Market forecast

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Hypoparathyroidism Drug Market - Industry Trends - Forecast to 2026

Global hypoparathyroidism drug market is expected to grow at a substantial growth of 8.1% CAGR in the forecast period of 2019-2026.  The emergence of drugs used in thyroid diseases, increases number of   thyroid cancer, development of newer technologies and vulnerable hypoparathyroidism patients enhancing the market growth.

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U.S. Vitamin D Supplements Market Size to Grow at a CAGR of 6.4% During the Forecast Period 2020–2025

U.S. Vitamin D Supplements Market size is $297Million in 2019, growing at a CAGR of 6.4% during the forecast period 2020-2025. Vitamin D plays a multi-functional role in the human body. It is known as the sunshine vitamin, as it is produced by the human body when the skin is exposed to the sun's ultraviolet rays. It is required for normal bone and teeth growth and development, protection against muscle weakness, and heart control. Owing to its greater consistency, ease of handling and storage, and versatility of use in a wide variety of items, the dry form of vitamin D is favoured by manufacturers. Vitamin D facilitates the absorption of calcium in the gut and retains sufficient serum concentrations of calcium and phosphate to enable normal bone mineralization and to prevent tetanus hypocalcemia. One in two Americans has a musculoskeletal disease that is estimated to cost the US $213 billion per year in terms of care and missed income, according to a study released by the US Bone and Joint Health Initiative. This led to an increase in the country's sales of vitamin-D supplements. Owing to the hectic lifestyle, growing health awareness, shifting dietary habits, and increasing demand for vitamin supplements, the growth of the market is driven by emerging cases of micronutrient deficiencies.

U.S. Vitamin D Supplements Market Segment Analysis - By Analog Type

In 2019, Vitamin D3 segment dominated the U.S. Vitamin D Supplements Market in terms of revenue owing towards the wide application in animal feed industry. The primary circulating source of vitamin D is calcifediol, and its blood levels represent the body's nutrient stores. It is found in fatty animal-sourced foods, like fish oil and egg yolk. When the skin is exposed to ultraviolet (UVB) radiation in the sunlight, vitamin D3 is naturally produced by the body and is also absorbed from the skin of animals such as sheep and cows. According to Public Health England (PHE), adults and children over the age of should have 10 micrograms (µg) of vitamin D every day abetting towards the growth of the market. Vitamin D2 is estimated to record the fastest CAGR of 6.6% during the forecast period 2020-2025 as it helps to avoid osteomalacia, hypoparathyroidism and hypophosphatemia from rickets and treats.

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U.S. Vitamin D Supplements Market Segment Analysis - By Distribution Channel

In 2019, E-Commerce segment dominated the U.S. Vitamin D Supplements Market in terms of revenue and is also estimated to grow at the fastest CAGR of 6.9% owing towards the efforts of retailers, through better online education and targeted marketing, to enhance the online shopping experience. The growing interest of U.S. customers in health and wellness goods is another primary growth driver of online sales. It is anticipated that quick and convenient online access to these goods would help businesses exploit this opportunity for growth. Pharmacies are estimated to record the fastest growth rate during the forecast period 2020-2025 owing to its wide variety of usage in health supplements as capsules and injectable.

U.S. Vitamin D Supplements Market Drivers

Increasing Consumer Awareness Of Labeling Claims And Dietary Supplements

Growth in perception of vitamin D deficiency is driving the Vitamin D market. According to the Health and Diet Survey conducted by the Food and Drug Administration (FDA), purchasing decisions based on product labelling are made by US customers. Owing to the country demographic trend of a rising ageing population, increasing lifestyle-related diseases, and increasing healthcare costs, preferences for dietary supplements are growing tremendously. Growing sales of sports nutrition are estimated to have a major effect on the industry with new product releases owing to increasing fitness patterns and sports activity is aiding towards the market growth.

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U.S. Vitamin D Supplements Market Challenges

Side Effects With Regulatory Concerns

The toxicity of vitamin D leads to calcium or hypercalcemia, leading to nausea, vomiting, fatigue and frequent urination is restraining the market growth. Regulatory concerns regarding the usage of U.S. Vitamin D Supplements and growing stringent government policy and regulation is hindering the market’s growth.

U.S. Vitamin D Supplements Industry Outlook

Product Launches, Merger & Acquisition, joint ventures and R&D activities are key strategies adopted by the players in the U.S. Vitamin D Supplements Industry. U.S. Vitamin D Supplements top 10 companies include Otsuka Holdings Co. Ltd, Nordic Naturals, Nature's Bounty Co., Pfizer Inc., Amway, Abbott Laboratories, GNC Holdings Inc., Everidis Health Sciences LLC, Glanbia Plc and GlaxoSmithKline.

Acquisitions/Product Launches

In July 2019, Pfizer, Inc. has acquired Array BioPharma Inc., advancing groundbreaking research to discover, produce and sell targeted small molecule drugs for the treatment of cancer and other diseases of high unmet need.

In December 2020, Nature's Bounty Co launched Nature's Bounty®. It contains vitamin D and zinc, as well as herbal ingredients such as Elderberry and Echinacea, for added immune and antioxidant help.

Key Takeaways

Children are increasingly advised to take vitamin D supplements, especially owing to its deficiency, which is mainly found in children, and also as it performs a host of physiological functions which drives the growth of the market.

Rising veganism trend and favourable government initiatives to improve healthcare infrastructure is likely to be the major driving factor for the market’s growth.

Increasing health consciousness and evolving dietary patterns is projected to record the fastest growth rate during the forecast period 2020-2025

Related Reports :

A. Vitamins And Nutrition Supplements Market

https://www.industryarc.com/Report/231/Vitamins-and-Nutrition-supplements-Market-report.html

B. Vitamin D Ingredients Market

https://www.industryarc.com/Research/Vitamin-D-Ingredients-Market-Research-508105

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Hypercalcemia Treatment Market (COVID-19 Impact) Insights 2021, Size, Global Trends, Industry Share, Growth Rate, Top Players, Business Opportunities, Demand Forecast 2026 | FMI

The global hypoparathyroidism treatment landscape that only gained much significance post the FDA approval of Natpara in 2015, is projected grow at a rather robust CAGR of approximately 8% through 2026. As per a recent in-depth analysis by Future Market Insights (FMI), the valuation of global hypoparathyroidism treatment market is expected to stand at US$ 663.7 Million in 2019. Although the growth rate is expected to showcase similar trends, the global hypoparathyroidism treatment market is still in its infancy, with most of the treatment options in various phases of clinical programs.

"The global hypoparathyroidism treatment market holds the potential to exceed the US$ 1.1 Billion mark by 2026, in terms of revenue. The treatment landscape for hypoparathyroidism-a rare endocrine disorder, characterized by high phosphate and low calcium levels, during low or inappropriately normal PTH level-will mostly be driven by increasing incidences of thoracic surgeries and cancer combined with Rising screening rates of thyroid diseases. Moreover, considering the rarity, hypoparathyroidism was classified as an orphan disease in European Union and United States. Considering which, favorable government schemes relating to orphan drug combined with tax incentives such as tax credits for qualified clinical trials and market exclusivity upon regulatory approval are some expected to translate into high return on investment for companies innovating drugs in hypoparathyroidism treatment market", explains a senior analyst.

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A Comprehensive Analysis of the Pipeline Clinical Programs for Hypoparathyroidism Treatment by FMI, Reveals:

There are around 47 ongoing clinical programs, globally, at different stages of development, wherein, 43 are interventional studies and 19 involve API with high potential market equity.

Most of these clinical programs are aimed at evaluating the efficacy of different treatment lines for hypoparathyroidism treatment, involving Calcitriol, calcium supplements, and magnesium.

Moreover, since hypoparathyroidism is the state of decreased secretion or activity of parathyroid hormone (PTH), close to 12 such clinical trials are focused on parathyroid hormone.

Of the total active clinical programs, phase III and phase IV clinical trials, collectively account for approximately 37.3 percent.

FMI, in its market study on hypoparathyroidism treatment also indicates that nearly 7 percent clinical programs stand terminated, suspended or withdrawn given their side-effects and failed efficacy.

Although approximately 45 percent clinical trials stand completed, most of the trials do not meet or partially meet the hypoparathyroidism treatment guidelines set by regulatory authorities.

Of the 47 percent active clinical trials, Shire continues to remain the leader in Hypoparathyroidism treatment clinical space with over 7 such active programs, followed by Entera Bio Ltd.

North America, accounting for nearly 57 percent leads the clinical trials landscape for hypoparathyroidism treatment, followed by Europe at 29 percent, as in 2017.

Preview Analysis On : Hypoparathyroidism Treatment Market Segmentation By Drug Class - parathyroid hormone, vitamin D analogue and calcium supplements; Route of Administration - Oral, Parenteral; Distribution Channels - Retail pharmacy, Hospital pharmacy, Online sales: https://www.futuremarketinsights.com/reports/hypoparathyroidism-treatment-market

Natpara Holds Approximately $2 Billion Market Opportunity, Reveals FMI

Considering a significant patient pool for hypoparathyroidism treatment and extremely low competition, Natpara is projected to showcase maximum revenue opportunity, with its demand expanding at magnificent CAGR of 145.8 percent, in the last few years.

Ever since its approval in 2015, Natpara has demonstrated a year-on-year growth of 72.8 percent through 2017

Despite labeling restrictions (Natpara Risk Evaluation and Mitigation Strategy (REMS) Program), considering Natpara's side effects including possible bone cancer (osteosarcoma) and high blood calcium (hypercalcemia), the U.S. currently accounts for 99 % of the total Natpara sales. In EU, sales of Natpara reached US$ 109.8 Million, in H1 2018-both the regions representing substantial revenue growth opportunities.

The bioengineered replacement biologic is also projected to drive significnat adoption of drug titration based on individual cases, translating into personalized medicines.

Hypoparathyroidism Treatment Market Showcases a Fairly Consolidated Landscape

Largely dominated by branded drug manufacturers, the competition in Hypoparathyroidism Treatment Market is projected to remain low through the forecast period of 2018-2026. Key leaders including EnteraBio Ltd., Shire-NPS Pharmaceuticals, Inc., and Teva Pharmaceutical Industries Ltd. account for nearly 50 percent market share, with a key focus on developing novel treatment options for hypoparathyroidism. Apart from new product innovations, key players are also expected to take the 'strategic acquisitions to expand global presence combined with increasing distribution channel' route to reach untreated patient pool. In Asia, India accounts for the highest hypoparathyroidism-related mortality incidences, compared to any other region, arising from lack of sufficient screening and treatment lines. However, on the other hand, large unmet treatment needs combined with long clinical trials, will translate into patients opting for alternative medications available in the form of calcium and vitamin generics, thereby increasing the buyer advantage.

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Insights Drawn From Segmentation Analysis of Hypoparathyroidism Treatment Market

While US dominates the hypoparathyroidism treatment landscape with 86 percent market share considering reasons mentioned, Asia Pacific is also projected to witness strong growth.

In terms of drug class, calcium supplements will remain the most preferred, with 38 percent market share. PTH will also showcase substantial growth rate.

On the basis of route of administration, parenteral method will remain the fastest growth segment, compared to oral methods.

Sales of hypoparathyroidism treatment drugs through retail pharmacies will generate maximum revenue, followed by hospital pharmacies.

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#Hypercalcemia Treatment Market #Hypercalcemia Treatment Market Size #Hypercalcemia Treatment Market Value

[riddhiochani]

Hypoparathyroidism Treatment Market is estimated to value over USD xx billion by 2027 end and register a CAGR of 8% from the forecast period 2020-2027.

The report initiates from the outline of business surroundings and explains the commercial summary of chain structure. Moreover, it analyses forecast By Drug Class, By Route of Administration, By Region and Hypoparathyroidism Treatment market.

#Hypoparathyroidism Treatment Market Analysis #Hypoparathyroidism Treatment Market Forecast #Hypoparathyroidism Treatment Market Growth

[factmrresearch1]

Calcium Lactate Market Insight

The global calcium lactate market size is expected to witness potential gains in the future, and register a significant CAGR of 1.7% in terms of value over the forecast period (2019 - 2027).

Market Overview

Calcium lactate is a salt that contains two lactate anions for each calcium cation (Ca2+). Calcium lactate is used to prevent and to treat calcium deficiencies such osteoporosis, osteomalacia/rickets, hypoparathyroidism, and latent tetany. Calcium lactate is found in daily dietary supplements as a source of calcium. Lactic acid is neutralized with calcium carbonate or calcium hydroxide to commercially prepare calcium lactate. According to the U.S. Food and Drugs Administration (FDA), calcium lactate can be used in food, except in infant foods and infant formulas, at levels not to exceed current good manufacturing practice. It is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener.

Market Dynamics

Increasing prevalence of calcium deficiency and associated diseases is expected to boost growth of the calcium lactate market. According to the International Osteoporosis Foundation, over 200 million people worldwide suffer from osteoporosis. Increasing geriatric population is also expected to contribute to the market size over the forecast period. People above 65 years of age may suffer from calcium deficiency. Calcium supplements in the form of gluconate, lactate, or phosphate can be used to strengthen bones.

However, high consumption of calcium lactate or any calcium supplement may lead to some health risks such as kidney stones, increased risk of prostate cancer, constipation, calcium buildup in blood vessels, and difficulty absorbing iron and zinc. According to the paper ‘Calcium and Calcium Salts’, published in the Journal of The Association of Physicians of India in February 2017, Calcium supplements are generally well tolerated; however, some patients complain of gastrointestinal symptoms, including constipation ,gas, flatulence, and bloating. Such adverse effects of calcium intake can hinder consumption of calcium lactate and affect market growth over the forecast period.  

Antioxidant peptides eliminate free radicals in the human body without harmful effects. Calcium lactate, along with glucose and casein peptone can be used to prepare such antioxidant peptides. Calcium lactate along with urea can also be used as a self-healing agent for cementitious materials crack repair. For instance, a team of researchers from Korea Advanced Institute of Science and Technology used urea–calcium lactate medium to produce CaCO3, which was later used to develop ureolytic/non-ureolytic bacteria co-cultured self-healing agent for repairing cracks in cementitious materials. Such advancements related to calcium lactate can boost its application in the pharmaceuticals and construction industries. Therefore, key players in the market can focus on commercializing such developments to enhance their market share.

Market Outlook

Asia Pacific is the fastest growing market in the global calcium lactate market, with China and India poised as major growth engines. This is attributed to significant growth in the pharmaceutical and food processing industries in the region. North America is also expected to witness significant growth in the calcium lactate market due to presence of major pharmaceutical companies such as Pfizer and Johnson & Johnsons.

Key Players

Key players operating in the global calcium lactate market include, Alfa Chemical Corporation, Wego Chemicals & Minerals Corp., Haviland Enterprises, Inc., and Action Labs Inc.

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Hypercalcemia Treatment Market Analysis (2020-2027)

Hypercalcemia is characterized by increased level of calcium in the blood. The condition can be life-threatening and is associated with neoplastic diseases. Hypocalcemic drugs are used for the treatment of hypercalcemia.

The global hypercalcemia treatment market is estimated to account for US$ 10,696.6 Mn in terms of value in 2018 and is expected to reach US$ 28,060.0 Mn by the end of 2028.

Global Hypercalcemia Treatment Market: Drivers

High incidence of hypercalcemia is a major factor boosting growth of the global hypercalcemia treatment market. For instance, in the study, ‘Incidence of hypocalcemia and hypercalcemia in hospitalized patients: Is it changing?’, published in the Journal of Clinical and Translational Endocrinology, in September 2018, researchers found that 27.72% of the study patients suffered from hypocalcemia and 4.74% from hypercalcemia. Moreover, 585 cases of hypercalcemia were detected.

Moreover, increasing prevalence of cancer is also expected to aid in growth of the market. For instance, according to the World Health Organization, around 18.1 million new cases and 9.6 million deaths were registered due to cancer worldwide in 2018.

Moreover, favorable reimbursement scenario is also expected to aid in growth of the market. Reimbursements enable lesser out-of-pocket costs of treatment for patients, despite having a low income eligibility. For instance, Amgen has a reimbursement policy on its XGEVA (denosumab injection), in which the company pays the out-of-pocket amount in excess of US$ 25 per dose; up to US$ 10,000 in assistance per calendar year. Approximately 70% of XGEVA patients with commercial or Medicare coverage incurred US$ 0 out-of-pocket cost due to favorable reimbursement policy offered by Amgen, Inc.

North America region held dominant position in the global hypercalcemia treatment market in 2018, accounting for 45.5% share in terms of value, followed by Europe.

Global Hypercalcemia Treatment Market: Restraints

Companies face challenges with regard to locating patients for clinical trials and logistics issues related to institutes conducting trials. Such factors increase the costs incurred in R&D of hypercalcemia treatment, which is expected to hinder growth of the global hypercalcemia treatment market.

Moreover, it is challenging to distinguishing primary hyperparathyroidism from conditions that will not respond to parathyroidectomy, which is also expected to limit growth of the market.

Global Hypercalcemia Treatment Market: Opportunities

Product innovations in hypercalcemia drug types other than bisphosphonates is expected to offer lucrative growth opportunities for players in the global hypercalcemia treatment market. Bisphosphonate is the single largest product being utilized for hypercalcemia treatment. End users have recognized the bisphosphonate therapy as effective. Still, the global hypercalcemia treatment market is yet to witness major product innovations in the product types of calcitonin, calcimimetics, and glucocorticoids.

Improving systems for recognizing hypercalcemia can aid in addressing common causes for delayed diagnosis and treatment of the disease, thereby aiding in growth of the market. Educating patients and providers about the consequences of untreated disease can also help in this regard.

Bisphosphonates segment in the global hypercalcemia treatment market was valued at US$ 7,306.2 Mn in 2018 and is expected to reach US$ 19,798.3 Mn by 2027 at a CAGR of 11.7% during the forecast period.

Market Trends/Key Takeaways

R&D in the treatment of hypercalcemia is augmenting growth of the market. For instance, in July 2019, researchers from Ascendis Pharma A/S, in their study, ‘Design and Preclinical Development of TransCon PTH, an Investigational Sustained?Release PTH Replacement Therapy for Hypoparathyroidism,’ reported that TransCon PTH can be used to normalize blood levels of calcium and phosphate.

Sarcoidosis, a complex disease with no known cause, is linked with hypercalcemia. The study, “Hypercalcemic pancreatitis a rare presentation of sarcoidosis: A case report,” published in the journal Medicine in January 2018, reported a sarcoidosis patient with pancreatitis — inflammation of the pancreas — and hypercalcemia.

Global Hypercalcemia Treatment Market: Competitive Landscape

Major players operating in the global hypercalcemia treatment market include, Bayer Pharma AG, Sun Pharmaceutical Industries Ltd., Mylan N.V., Pfizer Inc., Amgen Inc., Novartis AG, Dr. Reddy’s Laboratories Ltd., Cipla Inc., and XOMA Corporation.

Global Hypercalcemia Treatment Market: Key Developments 

Players in the market are focused on attending various conferences to expand their customer base. For instance, in October 2019, XOMA Corporation presented at the 2019 Cantor Fitzgerald Global Healthcare Conference held in New York.

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Parathyroid Disorders Market Analysis By Key Players, Development Trend, By 2023

Parathyroid Disorders Market Size, Application And Trends Analysis By Type (Hyperparathyroidism, Parathyroid Cancer, Hypoparathyroidism), Diagnosis (Blood Test, Imaging, Urine Test), Treatment (Surgery, Radiation Therapy, Drugs), End User – Global Forecast Till 2023

Key Players

Some of the key players in the global parathyroid disorders market are Abbott Laboratories, Alcon Laboratories, Inc., Amgen Inc., Bayer Healthcare, Becton, Dickinson and Company, Eli Lilly, Ethicon, Inc., Genentech, Medtronic, Merck, Mylan Laboratories, Novartis, Novo Nordisk, Pfizer, Roche, Smith & Nephew plc, Stryker, Teva Pharmaceutical Industries Ltd., Zimmer Biomet Holdings, Inc., and others.

Market Highlights:

A number of factors such as growing geriatric population, rising prevalence of parathyroid disorders, increasing government assistance, rising healthcare expenditure, improving regulatory framework, and rising funding and reimbursements are propelling the growth of the global parathyroid disorders market.

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However, challenges in research and development, side-effects of treatment, the presence of misbranded and spurious drugs, expiration of patented drugs, and poor healthcare system in low and middle-income countries may hamper the growth of the market.

It is estimated that the parathyroid disorders market is expected to grow at a CAGR 6.5% during the forecast period of 2017-2023. Parathyroid hormone plays a significant role in regulating the metabolism of calcium, phosphate, and Vitamin D. The hyperparathyroidism, and hypoparathyroidism are the two most common parathyroid disorders.

Segmentation

The global parathyroid disorders market is segmented on the basis of type, diagnosis, treatment, and end user.

On the basis of the type, the market is classified as hyperparathyroidism (HPT), parathyroid cancer, and hypoparathyroidism. The hyperparathyroidism is further sub-segmented into primary hyperparathyroidism, secondary hyperparathyroidism, and tertiary hyperparathyroidism.

On the basis of the diagnosis, the market is classified as blood tests, imaging tests, and urine tests. The imaging tests is further sub-segmented into CT or CAT (computed axial tomography) scans, MRI (magnetic resonance imaging) scans, X-ray, ultrasound, bone density test, and sestamibi scan.

On the basis of the treatment, the market is classified as surgery, radiation therapy, drugs, and others. The drugs segment is further sub-segmented into calcimimetics, hormone replacement therapy, and bisphosphonates.

On the basis of the end user, the market is segmented into hospitals & clinics, diagnostic centers, drug stores, pharmacies, and others.

Regional Analysis:

The Americas dominate the global parathyroid disorders market owing to the rising prevalence of parathyroid disorders and high healthcare expenditure. According to the Centers for Disease Control and Prevention in 2015, the total healthcare expenditure in the United States was reported to be USD 3.2 trillion and hospital care accounted for a share of 32.3%.

Europe holds the second position in the parathyroid disorders market. It is expected that the support provided by the government bodies for research & development and improvement in the reimbursement policies in the healthcare is likely to drive the market of the European region.

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The Asia Pacific is the fastest growing parathyroid disorders market owing to a huge patient pool and developing healthcare technology. Healthcare expenditure is also improving in various Asia Pacific countries. According to the Australian Institute of Health and Welfare in the years 2015-2016, the total healthcare expenditure was USD 170.4 billion, which is 3.6% higher than the expenditure of 2014-2015.

The Middle East & Africa holds the least market share due to lack of technical knowledge and poor medical facilities.

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[medicalnewstoday]

Hypocalcaemia Treatment Market to Witness Stellar Growth Rate in the Next 10 Years

Hypocalcaemia is imbalance of electrolytes which is indicated by abnormally low level of calcium in the body. A healthy person has 8.5-10.2 mg/dL calcium level in his/her body, however, drop in this level could possibly led to hypocalcaemia disorder. Middle aged population needs to take 1000 mg of calcium while geriatrics population aged 65 and above should take 1500 mg of calcium per day. Hypocalcaemia is caused by hypoalbuminemia, hyperphosphatemia, surgical effects, medication effects, hypomagnesemia, heart failure, muscle cramps, vitamin D deficiency, alcoholism, magnesium deficiency, insufficient protein in the blood, in the blood and many more. Neuromuscular irritability is the most common sign of hypocalcaemia. Hypocalcaemia are mostly diagnosed by clinical suspicion and laboratory testing. Hypoparathyroidism has a major effect on hypocalcaemia and high recurrence rate.

The hypocalcaemia can be caused at any age but it is commonly observed in ill patients and patients with parathyroid surgery and with increase in the prevalence of heat related disorders in the older population witnessing the growth of hypocalcaemia treatment market is expected to expand at considerable CAGR during the forecasted period. Also, with increase in the awareness among the aging population and availability of treatment creates an opportunity for hypocalcaemia treatment market worldwide. However, the biochemical abnormality associated with hypocalcaemia carries risks in diagnosis and treatment.

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The Hypocalcaemia Treatment Market has been classified on the basis of product, application, end use and geography.

Hypocalcaemia Treatment Market by type:

Asymptomatic

Symptomatic

Prophylactic

Hypocalcaemia Treatment Market by Drug type:

Radiocontrast

Loop diuretics

Calcium supplements

Antibiotics

Antiepileptic drugs

Estrogen

Bisphosphonates

Cinacalcet

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Hypocalcaemia Treatment Market by dosage forms type:

Calcium supplements

Vitamin D supplements

Parenteral preparation

Oral preparation

Parenteral preparation

Oral preparation

Parenteral calcium supplements dosage are given to patients suffering from acute hypocalcaemia. Whereas, in case of chronic hypocalcaemia oral calcium supplements are administered. Medical supervision is given to avoid risk associated with parenteral administration. With increasing demand for effective treatment of hypocalcemia, companies need to capitalize on their resources to offer effective medications and in turn further expand their business footprint in developing regions.

Depending on geographic region, hypocalcaemia treatment market is segmented into seven key regions: North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. Incidence rate of hypocalcaemia is quite high in North America compared to other regions. North America dominates the global hypocalcaemia treatment market followed by Europe, Asia Pacific owing to high awareness about the treatments of hypocalcaemia in these regions. The developing regions such as Asia Pacific, Middle East & Africa hold huge potential and is a promising market for hypocalcaemia treatment due to significant increase in medical tourism industry.

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Key players of Hypocalcaemia Treatment Market are;

Hoffman La Roche

Novo Nordisk

Sanofi

GlaxoSmithKline (GSK)

Pfizer Inc.

Ranbaxy Pharmaceuticals Ltd.

The report covers exhaustive analysis on:

Hypocalcaemia Treatment Market Segments

Hypocalcaemia Treatment Market Dynamics

Historical Actual Market Size, 2013 – 2015

Hypocalcaemia Treatment Market Size & Forecast 2016 to 2022

Hypocalcaemia Treatment Market Current Trends/Issues/Challenges

Competition & Companies involved

Hypocalcaemia Treatment Market Drivers and Restraints

#Hypocalcaemia Treatment Market

[healthcaremarketresearch201-blog]

Parathyroid Disease Treatment Market Size Statistics, Facts and Figures

Parathyroid Disease Treatment Market: Introduction

Parathyroid disease is characterized with abnormalities of serum calcium. Hyperparathyroidism, hypoparathyroidism, and parathyroid cancer are the three types of parathyroid disease. Primary hyperparathyroidism is a condition, in which too much parathyroid hormone is produced by the parathyroid gland. Parathyroid cancer is a rare disease often caused due to high level of parathyroid hormone. A study published in BMC Endocrine Disorder stated that parathyroid cancer is a rare endocrine malignancy primarily diagnosed in patients with primary hyperparathyroidism.

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Key Drivers and Opportunities of Global Parathyroid Disease Treatment Market

Rise in prevalence of parathyroid diseases is anticipated to boost the growth of the global parathyroid disease treatment market. An article published in PLOS, a study between 2003 and 2017, estimated that 13,897 admissions corresponding to 12,903 patients registered with parathyroid gland disorder were reported in Spain. According to Informa UK Limited, primary hyperparathyroidism (pHPT) is the third most common endocrine disorder.

Parathyroid problems are more common in younger adults (30 to 40 years) and older people. Hence, increase in the geriatric population is likely fuel the growth of the global market. According to an article published in journal of the Endocrine Society, a retrospective survey was conducted during January 1997 to June 2018, which estimated that 462 patients were diagnosed with primary hyperparathyroidism and 212 of them were aged above 65.

Focus on research & development by key players is anticipated to drive the global parathyroid disease treatment market. In June 2017, Amgen, Inc. received positive opinion from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) for Marketing Authorization of a pediatric formulation, Mimpara (cinacalcet), for children aged three years and older with secondary hyperparathyroidism (HPT).

However, product recall by the Food and Drug Administration is likely hamper the growth of the global parathyroid disease treatment market. For instance, in September 2019, the Takeda Pharmaceutical Company Limited issued the U.S. recall of NATPARA.

Increase in awareness about advanced therapeutics owing to rise in prevalence of parathyroid diseases in developing countries presents lucrative opportunities in the global market. Moreover, governments in developing countries are making significant investments toward modernization of health care infrastructure, which is likely to increase access to health care. This is expected to drive demand for advanced technologies.

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North America to Capture Major Share of Global Parathyroid Disease Treatment Market

North America is likely to account for major share of the global parathyroid disease treatment market during the forecast period due to high prevalence of parathyroid diseases. Additionally, well-established health care infrastructure in developed countries is projected to boost the growth of the market in the region.

The parathyroid disease treatment market in Asia Pacific is expected to grow at a rapid pace during the forecast period owing to rise in awareness and surge in geriatric population. An article published in the Indian Journal of Endocrine Metabolism stated that the incidence of asymptomatic primary hyperparathyroidism has been rising in the West, including India.

Key Players Operating in Global Parathyroid Disease Treatment Market

The global parathyroid disease treatment market is highly consolidated due to the presence of small number of key players. Demand for parathyroid treatment products has increased in emerging as well as developed markets owing to rise in prevalence of parathyroid gland disorder. Growth strategies adopted by leading players are likely to drive the global market.

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Major players operating in the global parathyroid disease treatment market are:

Amgen Inc.

Novartis AG

Global Parathyroid Disease Treatment Market: Research Scope

Global Parathyroid Disease Treatment Market, by Treatment

SurgeryMinimally Invasive Parathyroidectomy

Standard Neck Exploration

Others

TherapeuticsCalcimimetics

Bisphosphonates

Plicamycin

Hormone Replacement Therapy

Others

Global Parathyroid Disease Treatment Market, by Application

Hyperparathyroidism

Parathyroid Cancer

Hypoparathyroidism

Global Parathyroid Disease Treatment Market, by Region

North AmericaU.S.

Canada

EuropeGermany

France

U.K.

Italy

Spain

Rest of Europe

Asia PacificChina

Japan

India

Australia & New Zealand

Rest of Asia Pacific

Latin AmericaBrazil

Mexico

Rest of Latin America

Middle East & AfricaGCC Countries

South Africa

Rest of Middle East & Africa

More Trending Reports by Transparency Market Research – 1. https://www.prnewswire.com/news-releases/global-radiation-therapy-market-to-reach-us-8-6-bn-by-2026–product-approvals-to-drive-growth-transparency-market-research-300998453.html

2. https://www.biospace.com/article/dna-test-kits-market-increase-in-demand-for-ancestry-testing-to-drive-market/

[researchtrendingmarket-blog]

Hypoparathyroidism Drug Market - Industry Trends - Forecast to 2026

Global hypoparathyroidism drug market is expected to grow at a substantial growth of 8.1% CAGR in the forecast period of 2019-2026.  The emergence of drugs used in thyroid diseases, increases number of   thyroid cancer, development of newer technologies and vulnerable hypoparathyroidism patients enhancing the market growth.

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#Hypoparathyroidism Drug Market #Hypoparathyroidism Drug Market share #Hypoparathyroidism Drug Market size #Hypoparathyroidism Drug Market trends #Hypoparathyroidism Drug Market news #Hypoparathyroidism Drug Market report #Hypoparathyroidism Drug Market growth

[batstrangecloudcollection-blog]

Hypocalcaemia Treatment Market Set to Surge Significantly During 2016 - 2022

Hypocalcaemia is imbalance of electrolytes which is indicated by abnormally low level of calcium in the body. A healthy person has 8.5-10.2 mg/dL calcium level in his/her body, however, drop in this level could possibly led to hypocalcaemia disorder.

Middle aged population needs to take 1000 mg of calcium while geriatrics population aged 65 and above should take 1500 mg of calcium per day. Hypocalcaemia is caused by hypoalbuminemia, hyperphosphatemia, surgical effects, medication effects, hypomagnesemia, heart failure, muscle cramps, vitamin D deficiency, alcoholism, magnesium deficiency, insufficient protein in the blood, in the blood and many more. Neuromuscular irritability is the most common sign of hypocalcaemia. Hypocalcaemia are mostly diagnosed by clinical suspicion and laboratory testing. Hypoparathyroidism has a major effect on hypocalcaemia and high recurrence rate.

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The hypocalcaemia can be caused at any age but it is commonly observed in ill patients and patients with parathyroid surgery and with increase in the prevalence of heat related disorders in the older population witnessing the growth of hypocalcaemia treatment market is expected to expand at considerable CAGR during the forecasted period.

Also, with increase in the awareness among the aging population and availability of treatment creates an opportunity for hypocalcaemia treatment market worldwide. However, the biochemical abnormality associated with hypocalcaemia carries risks in diagnosis and treatment.

The Hypocalcaemia Treatment Market has been classified on the basis of product, application, end use and geography.

Hypocalcaemia Treatment Market by type:

Asymptomatic Symptomatic Prophylactic

Hypocalcaemia Treatment Market by Drug type:

Radiocontrast Loop diuretics Calcium supplements Antibiotics Antiepileptic drugs Estrogen Bisphosphonates Cinacalcet

Hypocalcaemia Treatment Market by dosage forms type:

Calcium supplements Parenteral preparation Oral preparation Vitamin D supplements Parenteral preparation Oral preparation

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Parenteral calcium supplements dosage are given to patients suffering from acute hypocalcaemia. Whereas, in case of chronic hypocalcaemia oral calcium supplements are administered. Medical supervision is given to avoid risk associated with parenteral administration. With increasing demand for effective treatment of hypocalcemia, companies need to capitalize on their resources to offer effective medications and in turn further expand their business footprint in developing regions.

Depending on geographic region, hypocalcaemia treatment market is segmented into seven key regions: North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. Incidence rate of hypocalcaemia is quite high in North America compared to other regions. North America dominates the global hypocalcaemia treatment market followed by Europe, Asia Pacific owing to high awareness about the treatments of hypocalcaemia in these regions. The developing regions such as Asia Pacific, Middle East & Africa hold huge potential and is a promising market for hypocalcaemia treatment due to significant increase in medical tourism industry.

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Market Players

Key players of Hypocalcaemia Treatment Market are :

F. Hoffman La Roche, Novo Nordisk, Sanofi, GlaxoSmithKline (GSK), Pfizer Inc., Ranbaxy Pharmaceuticals Ltd.

#Hypocalcaemia #Hypocalcaemia Treatment #Healthcare

[market-insights-dbmr]

Global Orphan Drug Market 2019 Worldwide Robust Expansion by Top Key Manufactures, Overview, Size, Share, Trends, Segments, Demand and Forecast to 2025

Global orphan drug market is rise gradually to an estimated value of USD 326.25 billion by 2026 registering a CAGR of 8.5% in the forecast period of 2019-2026. Growing number of orphan diseases, accelerating novel therapies and orphan drug development programs and exclusive incentives from the government are the key factors for market growth.

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Few of the major competitors currently working in the global  orphan  disease market are F. Hoffmann-La Roche Ltd.,  Novartis AG, Pfizer Inc., AbbVie, AstraZeneca, Baxter, Eli Lilly and Company, Johnson & Johnson Services Inc., Merck KGaA, Novo Nordisk A/S, Bristol-Myers Squibb Company, Alexion Pharmaceuticals, Kyowa Hakko Kirin Co., Ltd., Amgen Inc., Biogen, Celldex Therapeutics, GlaxoSmithKline plc., Eisai Co., Ltd., Takeda Pharmaceutical Company Limited, Vertex Pharmaceuticals Incorporated (US)  and among others.

Key Developments in the Market:

In August 2018, Kyowa Hakko Kirin Co., Ltd received the FDA approval for Poteligeo (mogamulizumab-kpkc) injection, an Orphan Drug, for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sezary syndrome which are the types of non-Hodgkin lymphoma

In August 2018, Takeda Pharmaceutical Company Limited received FDA approval for Takhzyro (lanadelumab-flyo) injection for the treatment to hereditary angioedema (HAE) attack in patients 12 years of age and older

In June, 2018, Ascendis Pharma A/S received the FDA Orphan Drug Designation for TransCon PTH for the treatment of hypoparathyroidism. TransCon PTH is a long acting parathyroid hormone replacement therapy which helps in restoring the activity of parathyroid hormone

Competitive Analysis:

Global orphan drug market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of orphan drug market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

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Segmentation: Global Orphan Drug Market

By Disease Type

(Oncology disease, Metabolic Disease, Hepatology, Immunology, Infection, Neurology and Others),

Drug Type

(Biological, Non-Biological, and Others),

Indication Type

(Non-Hodgkin Lymphoma, Acute Myeloid Leukemia, Cystic Fibrosis, Glioma, Pancreatic Cancer, Ovarian Cancer, Multiple Myeloma, Duchenne Muscular Dystrophy, Renal Cell Carcinoma and Others),

Drug class

(Lenalidomide, Rituximab, Glatiramer Acetate, Nivolumab, Interferon Beta-1a, Ibrutinib, Cinacalcet Hydrochloride, Imatinib Mesylate, Bortezomib, Sodium Oxybate and Others),

Therapy Type

(Medication, Surgery and Others),

Route of Administration

(Oral, Intravenous and Others),

End- users

(Hospitals, Homecare, Specialty Clinics, Others),

Geography

(North America, South America, Europe, Asia-Pacific, Middle East and Africa)

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[ajjpatil]

Hypoparathyroidism Treatment Market 2019- Global Industry Details by Overview, Size, Top Manufacturers, Trends, Demand, Overview, Forecast to 2025

Hypoparathyroidism Treatment Market By Drug Class (Vitamin D Analogue, Parathyroid Hormone, Calcium Supplements) Route of Administration (Parenteral, Oral) Distribution Channels (Hospital Pharmacy, Retail Pharmacy, Online Sales) - Global Industry Analysis & Forecast to 2025

Industry Outlook and Trend Analysis

The Hypoparathyroidism Treatment Market has encountered significant development over the recent years and is anticipated to grow tremendously over the forecast period. The uncommon condition named hypoparathyroidism includes the decrease in the activity parathyroid organs. The most well-known way a patient can experience the ill effects of hypoparathyroidism is after the parathyroid organs get expelled or harmed amid medical procedure. It is a condition of low parathyroid hormone discharge and can cause an extreme drop in calcium levels in the blood and also elevated amounts of phosphorus in the blood. Side effects for hypoparathyroidism run from mellow shivering in fingers, hands, or the mouth, to more genuine and agonizing muscle cramps. Exceptionally uncommon indications displayed by patients incorporate spasms and outrageous muscle cramping of the entire body.

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Drivers and Restraints

The developing screening rates, expanding number of thoracic medical procedures and occurrence of disease are anticipated to be the prime elements driving the development of the hypoparathyroidism treatment market. Thyroid or neck surgery is related with hypoparathyroidism, inferable from harm to the parathyroid organs. The quantity of thyroidectomies in the U.S. reflects 39% expansion from 2007 to 2015. Expanding interests in the innovative work combined with the advancement of biologics is foreseen to produce energy and development opportunities for the hypoparathyroidism treatment market.

Regional Insights

North America will be the potential market for the players as there is major demand for the product, and the players are also coming with new product with proper FDA approval.

By Region

·         North America

o   U.S.

o   Canada

o   Mexico

·         Europe

o   Germany

o   UK

o   France

o   Russia

o   Italy

o   Rest of Europe

·         Asia-Pacific

o   China

o   Japan

o   South Korea

o   India

o   Southeast Asia

o   Rest of Asia-Pacific

·         South America

o   Brazil

o   Argentina

o   Columbia

o   Rest of South America

·         Middle East and Africa

o   Saudi Arabia

o   UAE

o   Egypt

o   Nigeria

o   South Africa

o   Rest of MEA

Competitive Analysis                         

The major players in the market are profiled in detail in view of qualities, for example, company portfolio, business strategies, financial overview, recent developments, and share of the overall industry.

F. Hoffmann-La Roche Ltd

WCCT GLOBAL INC

Novartis AG

Shire-NPS Pharmaceuticals, Inc

EnteraBio Ltd

Takeda Pharmaceutical Company Limited

GlaxoSmithKline plc

Some of the key questions answered by the report are:

What was the market size in 2014 and forecast from 2015 to 2025?

What will be the industry market growth from 2015 to 2025?

What are the major drivers, restraints, opportunities, challenges,     and industry trends and their impact on the market forecast?

What are the major segments leading the market growth and why?

Which are the leading players in the market and what are the major     strategies adopted by them to sustain the market competition?

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#Hypoparathyroidism Treatment Market