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NGC 6302, Butterfly

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Strawberries anyone?

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albertdrosphotography

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Well it was my birthday and I said I had something special in mind…

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A whale near a boat | Source

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New research led by the Doherty Institute has found the SARS-CoV-2 virus has the ability to momentarily accelerate its evolutionary pace, enabling variants to emerge more rapidly than other viruses.  

Recently published in Molecular Biology and Evolution, the team, led by University of Melbourne Dr. Sebastian Duchene, an Australian Research Council DECRA Research Fellow at the Doherty Institute and lead author on the paper, found the virus that causes the disease COVID-19 is actually undergoing short-lived mutational bursts and then returning to its ‘normal’ rate.

Dr. Duchene explained that usually all viruses mutate at a fairly constant rate, with most taking a year or more to develop a new variant. 

 "However, what we were seeing with the variants of SARS-CoV-2, particularly the variants of concern, is that they have undergone many more mutations than we would expect under the normal evolutionary pace of similar coronaviruses,“ Dr. Duchene said. 

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Baby elephant thought man was drowning and rushed to save him

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warp

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Hungry hungry hippos

(via)

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Children Use Both Brain Hemispheres to Understand Language, Unlike Adults

Infants and young children have brains with a superpower, of sorts, say Georgetown University Medical Center neuroscientists. Whereas adults process most discrete neural tasks in specific areas in one or the other of their brain’s two hemispheres, youngsters use both the right and left hemispheres to do the same task. The finding suggests a possible reason why children appear to recover from neural injury much easier than adults.

The study, published in PNAS, focuses on one task — language — and finds that to understand language (more specifically, processing spoken sentences), children use both hemispheres. This finding fits with previous and ongoing research led by Georgetown neurology professor Elissa L. Newport, PhD, a former postdoctoral fellow Olumide Olulade, MD, PhD, and neurology assistant professor Anna Greenwald, PhD.

“This is very good news for young children who experience a neural injury,” says Newport, director of the Center for Brain Plasticity and Recovery, a joint enterprise of Georgetown University and MedStar National Rehabilitation Network. “Use of both hemispheres provides a mechanism to compensate after a neural injury. For example, if the left hemisphere is damaged from a perinatal stroke — one that occurs right after birth — a child will learn language using the right hemisphere. A child born with cerebral palsy that damages only one hemisphere can develop needed cognitive abilities in the other hemisphere. Our study demonstrates how that is possible.”

Their study solves a mystery that has puzzled clinicians and neuroscientists for a long time, says Newport.

In almost all adults, sentence processing is possible only in the left hemisphere, according to both brain scanning research and clinical findings of language loss in patients who suffered a left hemisphere stroke.

But in very young children, damage to either hemisphere is unlikely to result in language deficits; language can be recovered in many patients even if the left hemisphere is severely damaged. These facts suggest that language is distributed to both hemispheres early in life, Newport says. However, traditional scanning had not revealed the details of these phenomena until now. “It was unclear whether strong left dominance for language is present at birth or appears gradually during development,” explains Newport.

Now, using functional magnetic resonance imaging (fMRI) analyzed in a more complex way, the researchers have shown that the adult lateralization pattern is not established in young children and that both hemispheres participate in language during early development.

Brain networks that localize specific tasks to one or the other hemisphere start during childhood but are not complete until a child is about 10 or 11, she says. “We now have a better platform upon which to understand brain injury and recovery.”

The study, originally run by collaborators William D. Gaillard, MD, and Madison M. Berl, PhD, of Children’s National Medical Center, enrolled 39 healthy children, ages 4 to 13; Newport’s lab added 14 adults, ages 18 to 29, and conducted a series of new analyses of both groups. The participants were given a well-studied sentence comprehension task. The analyses examined fMRI activation patterns in each hemisphere of the individual participants, rather than looking at overall lateralization in group averages. Investigators then compared the language activation maps for four age groups: 4 to 6, 7 to 9, 10 to 13, and 18 to 29. Penetrance maps revealed the percentage of subjects in each age group with significant language activation in each voxel of each hemisphere. (A voxel is a tiny point in the brain image, like a pixel on a television monitor.) Investigators also performed a whole-brain analysis across all participants to identify brain areas in which language activation was correlated with age.

Researchers found that, at the group level, even young children show left-lateralized language activation. However, a large proportion of the youngest children also show significant activation in the corresponding right-hemisphere areas. (In adults, the corresponding area in the right hemisphere is activated in quite different tasks, for example, processing emotions expressed with the voice. In young children, areas in both hemispheres are each engaged in comprehending the meaning of sentences, as well as recognizing the emotional affect.)

Newport believes that the “higher levels of right hemisphere activation in a sentence processing task and the slow decline in this activation over development are reflections of changes in the neural distribution of language functions and not merely developmental changes in sentence comprehension strategies.”

She also says that, if the team were able to do the same analysis in even younger children, “it is likely we would see even greater functional involvement of the right hemisphere in language processing than we see in our youngest participants (ages 4 to 6 years old).

“Our findings suggest that the normal involvement of the right hemisphere in language processing during very early childhood may permit the maintenance and enhancement of right hemisphere development if the left hemisphere is injured,” Newport says.

The investigators are now examining language activation in teenagers and young adults who have had a major left hemisphere stroke at birth.

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An Eden’s whale trap feeding in the Gulf of Thailand

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Skating on clear ice in Colorado | source                         

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Amazing Synchronism from Mayyas Dance Crew students of Lebanon.  

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