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#ischemic
ricisidro · 1 year
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U.S. #FDA, #CDC see early signal of #Pfizer #bivalent #COVID shot's link to #ischemic stroke to people 65 and older. #COVID19 #Omicron #COVID19Vaccine #CovidVaccine #Booster https://www.instagram.com/p/CnYde64rfrs/?igshid=NGJjMDIxMWI=
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reasonsforhope · 1 year
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A large trial investigating the effectiveness of a celery-seed-derived neuroprotectant drug for use in ischemic stroke cases has shown significant promise.
Patients given the medicine called butylphthalide had a 70% better chance of improved neurological and general living outcomes 90 days post-stroke, a finding generated from a little over 1,000 cases.
Butylphthalide is already approved for use in treating strokes in China. Currently though, the FDA has not approved it for any use.
How butylphthalide works isn’t clear, with animal studies suggesting various possible mechanisms. It may help protect brain tissue from damage when the supply of oxygenated blood is cut off and it works alongside existing clot-busting drugs or procedures to remove blood clots in ischemic stroke conditions.
The trial consisted of 1,216 patients who were admitted for stroke in China where the drug is approved for use, and given it alongside a tissue plasminogen activator (tPA) and/or a mechanical clot removal procedure—two primary means of dealing with ischemic, or clot strokes.
Every year, more than 795,000 people in the United States have a stroke, with 87% of these being ischemic ones. The burden of these events is large, and they are a leading cause of disability in the elderly.
“This is the first trial to show the benefit of using a medication that protects the brain from damage caused by a lack of oxygen to brain tissue...” said Baixue Jia, M.D., co-author of the study...
The results will soon be presented to the International Stroke Conference this week in Dallas, Texas.”
-via Good News Netwwork, 2/6/23
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scratchandplaster · 1 year
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Stack The Deck - PART 8
CW: toxic relationship, abuse of various kinds, misogyny, stalking, manipulation, injury, Carewhumper, reluctant Whumper
PART 7 ⇽ [Masterlist] ⇾ PART 9
・・・・・・・・・・・・・・・・・・・
[2 WEEKS AGO]
They didn't sleep a lot this night, an event Morris never complained about. Flitting across the room, Amber was busy to collect the few clothes she carried on her body the day before. Her hair seemed a bit more dull than usual, wild and sprinkled with the smell of cheap vodka. She jumped into her oversized jeans. Hopping on one leg, clearly trying to keep her balance, yesterday's excess still weighing her down. He adored her so much, his heart stopping its beat for just a second.
"Whatcha looking at?" She turned to face him, an eyebrow playfully raised. Teasing.
"Just you," he whispered, sleep sticking to his voice, making it sound rough and hungry, "do you need to leave already? I thought we could spend the day together?"
Sharing a knowing smile with Morris, she continued to dress herself haphazardly, throwing pieces of fabric over herself to fight the freezing cold outside. She appeared more hectic than usual.
In a few hours, this nervousness would turn into itches burrowed directly under her skin, crawling their way inside her bones. They would be together by then, Morris hoped, always ready to allay her pain. That's what he wanted, what he was here for.
"Can't," she finally revealed, "'m busy with work." You don't work.
"Oh, alright!", he retorted instead, forgiving her quick lie without thinking anything by it, ""What about tonight? We could watch a movie..."
"I'm busy."
"Well, how about-"
"Planned the whole week, sorry." She didn't, he checked thoroughly.
"What about yesterday? You had enough time for me there."
Something was wrong, he could feel it, they usually didn't take long breaks from each other. She called him whenever her stash ran short, knowing that she doesn't get anything better than what Morris has to offer. A little extra, just for you, Amber.
Her expression soured, emerald eyes pressing together to form thin slits: "What's that supposed to mean?"
Morris didn't mean to fight, honestly trying his best to mediate the rising tension between them. Nevertheless, Amber made it hard to stay calm. He sat himself up to get a better look at her, distracted by zipping up her boots. As if he wasn't even in the room.
"I just think we should spend more time together, that's all!"
She was fully dressed by now and ready to leave, more fidgety than normal, it couldn't be the beginning withdrawal that made her so on edge. Twitching uncomfortable, she continued to face him.
"And what do you want to do with all that?"
He usually found her jokes to be cute, but this was different. Malicious even.
"This!" he stated bewildered, not knowing how else to respond, "This is all I'd ever want. You, me...us."
"This?" Amber sounded agitated, no, offended, like he just insulted her mother. "This is nothing, everyday living. One day you wake up, and your whole life is spent in what? Routine?"
She probably was just irritated, he had to track her cycle again, to avoid conflict. Whatever hormones she was suffering under currently, it didn't give her the right to-
She interrupted his sympathetic line of reasoning, more than angry: "What exactly do you think we are, huh?"��
What a question.
"Amber, this is serious...We-we talked about this months ago!"
"When I feel like it is, sure. Once you got the 'yes' I hoped you would stop being so fucking clingy."
He was standing at last, his hair tousled in all directions, it gave his confusion an even more convincing look. 
"See, I need to go. I call you after work." He probably should have let it go by then, but that wasn't his manner.
"Yeah? After the work you quit six weeks ago because you don't have to finance your little habit anymore; you can just tap me any time of day, right?!"
In disgust, she stopped looking for her purse to scowl at Morris, caught in her own little scheme, still never going to admit it. He knew her better than anyone else could.
"Whatever you think to know about my business, you have no fucking idea what you're talking about. Pathetic."
None of them realized how quickly it escalated, him storming towards her and halting just inches apart. Tall enough to look down on her, he spoke with the most collected tone he could muster in this situation.
"I take care of you, give you everything you want and that's how you talk to me?"
"A lot of people do these days," she spat in his face, taking every sliver of kindness out of the air between them, "and I'll replace you in a second, if you force me to."
Morris clenched his teeth to the point of nearly bursting his enamel, planting himself in front of her to take as much space as possible.
She doesn't mean it, but that doesn't give her the right to treat me like that!
Convinced that he did nothing wrong, he remained in this sorry excuse of a threatening posture.
Amber wouldn't budge an inch. She knew exactly how to handle men like Morris, she met them often enough and every time, it turned out the same.
"I'm leaving," she spoke with an unknown malice to her self-proclaimed boyfriend, "don't expect me to come back."
With that, she turned towards the door, trying to get out of the bedroom and to the one separating them from the hallway, hopefully without any disturbance. Morris turned with her, blocking the exit. She couldn't just leave like this, he needed her to listen!
"I'll scream, Chris!" her voice now a few pitches higher, fright clawing its way up her spine, "one call and the police will drag you back where you belong."
With that, she quickly squeezed past him and leaped down the stairs, leaving the door to hang open.
His vision white with anger but too frozen to do anything about it, Morris tried to sort his racing thoughts. He had known her to be less than loyal, sure, having fun was nothing to be ashamed of. But nobody just lets him stand in the dark like an idiot. Whatever poor soul she replaced him with - he couldn't bear the idea of it, thinking about it more like a quick change in scenery - he would be ready to forgive that slip-up too. He was patient enough for that, for her. She would learn that soon enough.
He had nothing to worry about, her imprudence would work in his favor. A few days at best, and she lays right where she belongs.
"You will crawl back to me, begging for my forgiveness!“ he screamed down the abandoned stairway, "Just you wait!"
--------
Elliot wondered if he would know anything besides unconsciousness. It felt more familiar by now, not that it bothered him: he preferred the thoughtless drifting over the waking world.
He understood nothing while laying in the stinted niche, his whole arm pulsating in heat. It had spread from his last two digits towards his elbow and further to the back of his neck. Wet and shaky, the limb continued to lay uselessly on the towel, blood-soaked, like everything else around him.
Elliot didn't want to recognize the familiar pressure next to him, like a shadow waiting to be seen. His captor hadn't moved in quite a while, impossible to pass even when asleep. The door leading to the garage and outside probably wasn't locked, he was practically free to go. 
Yeah, sure. 
God knows what Morris would rip out of him, if he dared to even look in the wrong direction. So he didn't.
The empty can was placed neatly on the mattress. Deep inside, he hoped Morris would just drug him up, let him forget the heat, the deep pain, the fact he would never sit at a piano again... Maybe he should cut that thing off, make it all go away.
Don't think about that, don't...
Tiny sniffles made their way up his nose. He would wake him up, he would come to and just make everything worse, Elliot was sure. The quiet weeping made him unaware of the silhouette shifting beside him, only a little, to place its meaty paw onto his shoulder.
"Don't cry, it's alright." 
It patted along the giant jacket enclosing Elliot, making his nerves flare up in agony once again. Screaming and crying: not fun, so shut the fuck up, come on...
"I've torn a ligament in my knee once, physical therapy really did its wonders." He ought to curse Morris out by now, but couldn't find a single spark of anger anymore, he was drained. "Your insurance should cover that, I hope."
No response came to guarantee Morris his incapacitated playmate was still up for a round. Trying wouldn't kill him, though.
"You wanna go back to the living room while we wait? It's warmer anyway, but if you still need to throw up, I can stay here."
Nothing. Playing hard to get, Morris assumed, he could handle that.
"She must really hate me, huh?" Elliot whispered instead. 
Please don't hurt my family. He thought of Ginkgo too, and how she would only survive for a week without him, like he deserved it for being always so fucking useless to everyone...
Morris dug through his back pocket, pulling out the stack of cards, nicked and smeared with what had swept out of him hours ago. It was time again if he wanted to or not.
I bore him, Elliot grasped, wanting to burst out laughing, like a bad episode he just wants to skip.
Quickly shuffling through the stack, he dealt them out as before, not being satisfied with solitaire or building a simple house of cards. Morris had spent so much energy to not hate the unfamiliar man, someone who had no fault regarding his experience with Amber. It used to feel like it, in a way, but not anymore. They were the same.
"You can start whenever you like!", he offered friendly, shifting to face Elliot, who still laid on his side.
Am I going to lose a foot if I decline? Or will you beg for my attention again?
"I never know what's the matter with you..." Elliot said instead, way too loud and not even meant to leave his head.
"I just want to make this easy for us - for you. Like yesterday, it went so well, better than I had expected."
Proud of managing his first-ever job without any assistance, Morris forgot for a second how everything after their boozy session went downhill. He wanted to hear about Elliot again, his hobbies, his life. We should start on common ground.
So he asked about the only thing really catching his attention:
„How did you meet Amber? You seem like a killjoy to me, not somebody she would drag around the nightlife."
"Houseparty of a mutual friend, Sarah, you know her? Contralto."
Of course, Morris knew her, she gave him a displeased look or two during their time together. Because he didn't belong to them, without Kant and Doc Martens. So he pretended to, just like right now, planning to google that word later in the day.
Elliot was turning absent again, he just parroted back the small talk.
"What about you?" A little meet-cute at the crack house? Wait-
"I don't think you wanna hear this," Morris continued, a bit quieter than normal. He shoved a few loose cards towards him.
No, nononono-
Through the fevered heat that started to crawl up his nape, he could finally see clear. He paid with two of his fingers to get the answer he was searching for.
"We met online and had a few drinks, nothing special." LIAR.
"Before or after?" he asked, nearly impossible to snuff out painful laughter. Morris just looked back at him with confusion. "Did she fuck you before or after you sold her weed?"
No answer to that, not that Elliot was in need of one. Twice in a year, this man ruined his life, and it took him way longer than expected to realize it.
"She always told me about a pharmacist," Elliot spoke to the ceiling above, to anyone who would listen, "and about how he would treat her so much better than I do, how ungrateful I was."
Morris didn't say a word, back to his stoic self. A lot more crest-fallen, admittedly, collecting the playing cards again.
"She loves this, her little fairy tales. Needs it. And when you're not worth the attention anymore, you get replaced, rebranded."
Morris knew it was a cocktail of the spreading infection paired with an old wound ripped open, he just wished back the Elliot who treated him with respect, like an actual human being. 
"You don't just break up with her like that, Elliot."
"Fuck, I sure did. If she cheats, what else are you supposed to do? Be alone, Morris, better alone than trapped."
"I have to do this. I have to. That's the last chance I get," Morris tried to convince Elliot, or maybe just himself.
"Nobody's making you do this. It's just you, always has been... Crippling me because a girl ghosts you, do you even hear yourself?"
His fleeting politeness didn't linger to aid his survival. Morris sounded like a toddler by now, unbelievable that this would be the man to ultimately end his life. Killed by a butthurt man-child, what a way to go. Elliot took it personally, though, he had every right to.
Morris would lose his calm any second to jump on top of him: strangling, stabbing, slicing. It was just a matter of time.
"I need to change that," he murmured, pointing to the dirty gauze and letting his mind drift far away from the accusations Elliot threw at him.
If it's delivered, her phone's on. And when it's on, she uses it. There was no other explanation, right? 
"Don't! I don't want your help!" 
Still, Elliot had no strength to resist the force with which his hand was taken from him, gently turned to be inspected.
"Look away!" he was told, while the jacket draped over his head to obscure the sight.
Please, I need to see, I need to know how bad it is. 
No matter how much he had insulted him just moments prior, Morris was so careful with his limb. A limb that was still attached to the rest of the infection-stricken man.
He didn't cut them off, Elliot realized, he didn't cut them off because he likes me.
He was correct with that assumption. Morris found joy in his captive, making the sight even harder when he pulled down the bandages. The whole upper part of Elliot's fingers were tinted in a cold blue, dark and unnatural to the sight. Tissue around the cuts was soft, providing no resistance when held. Like Play-Doh.
Morris thought of the medical dramas Amber forced him to watch more than once, but this was different. Squirming in the grasp, it was apparent that Elliot tried his best to stay still. Further up the digits, another agitator fell into his gaze: What had been white bloodless spots evolved into blisters.
Not blisters really, wet and open circles of infection, beginning to turn black in the middle. Morris thought of the bogman they pulled out of his grandmother's moorland when he was just about five. A hiker, the police told the villagers. It also smelled like it, decay tainting the bathroom.
"Does it look alright?" a thin voice came forward. No, it didn't.
"Sure, just as I said. A few screws and you're good as new." Morris needed to get more pills into his system, anything to help him overcome this. Amber should call any minute now, he hoped, claiming her to be sick for leading them on for such a long time.
------
I'm sorry, please call back. We can make this work.
Why don't you answer? I just want to explain myself!
Did you get a new number? Don't ignore me.
Are you with him again?
I have ways of making you talk to me, I'll make you regret your stubbornness.
Don't force me to do this.
After that, he had sent the first picture. Elliot in the stuffy trunk, bound like a birthday present and smeared with blood all over his face, blissfully unaware of the days to come. She had to have witness that, at least. Morris imagined her sitting together with her friends, laughing about how desperately he tried to get anywhere with her. Pathetic fit him.
He should have accepted Elliot's advice, snatch up one of those shallow leeches to mistreat instead. Rhys, that annoying prick always trying to start shit about current politics or Liz, dumb as a rock and twice as bland. Or Sahra, always at the butt of the joke.
Why not, actually, she didn't seem to be one to enjoy Amber. Sometimes, at least. Rummaging through Elliot's contacts, he quickly found what he was looking for. He couldn't fuck this up even more, so what was left to lose?
"Hello?" a confused voice answered, probably annoyed about being disturbed on a Sunday morning.
"Hey, Sahra. It's Chris!" Don't you dare hang up, don't complicate this further! "I just wanted to ask how you're doing!"
Silence.
"If you're searching for Amber, she not with me right now."
Short and brutal, she explained what he already knew. After the standstill on her socials, Amber didn't even visit her favorite bars or clubs, not even Sahra. He checked that.
"And she's still pissed about your fight, so don't expect anything from me."
Morris tried to take her gossiping lightly, wanting to get more information.
"Yeah, I know. It didn't go as planned, I tried to make amends, but she just went AWOL everywhere. Can't blame her for avoiding me." Hoping she would take the bait, Morris waited a second to let his desperation seep through the speaker. "By the way, how is your practice going?"
"What do you care?"
Bitch. With a glimpse towards the bathroom door, Morris walked up and down the living room, keeping the chit-chat going. What was the word again?
"I wanted to get us both tickets, Amber and me, for the show. You perform this Christmas, don't you? Wanted to bring on the advent spirit, just a little." Come on.
"Oh yeah, that's true," she admitted, a bit more gentle now. "I didn't know you kept that in mind."
"Contralto, right? I just want to make it up to her, but she ignores me ever since. I guess that's what I deserve..."
A sigh could be heard at the end of the line, he could practically hear her chewing her lip.
"Listen, Chris, that's sweet of you. But I don't think she will be able to go, even if she wanted." A horrible accident was the only acceptable reason for her behavior. He could visit her, bring her flowers, tuck her back into bed...
"Oh my god," he gasped instead, "please don't tell me it's something bad. I always told her to drive slower, I couldn't-"
"No, no, don't worry," came the hectic answer, "Well, maybe worry a little. I don't know if you should-"
"I just want to know if she's hurt! Please, Sahra, I agonized over this for two weeks!" Swallow that whole, you fucking cunt.
"You didn't hear that from me, okay?"
"I didn't hear anything!" He was close, so close.
"Fuck, Chris, she's in rehab."
For a second, Morris thought of nothing, like every plan and problem he juggled for the past weeks had left him for good. Rehab? No, she doesn't need that. He could take care of her, he could make it better... She didn't need that!
"Bought impure stuff. Some bastard cut it with heroin."
"Oh," he said flatly, "fucking hell."
Her information was still wrong, Amber didn't buy it.
"Yeah, but the outcome is nice, I suppose. Vegan buffet, aquarobics and all that bullshit. I just hope she's doing fine. It's some alternative place her parents picked out, no Wi-Fi and all that, they don't even allow them phone calls. I tried to reach her too, but no chance. You know, I always suspected-"
He let her tell the stories of Ayurveda treatments and deep cleansing methods in between therapy sessions and how long that might take. Weeks, she suspected. Time neither Morris nor Elliot had left, especially not here.
She hadn't seen any of it, any of the things he did for her.
Why didn't he call earlier, why did he give into the fantasies of getting back at her through hurting a man - hurting Elliot? Silently, he called himself every insult in the book, his self-image being drowned in shame. Morris had never been idiotic, though, the truth was considerably more wearing. Jealous, that's all he was.
"Chris?" It's been him, it has always been him. "Why did you argue?"
"She hurt someone," he answered automatically, his mouth as dry as the now blood-stained grout, "Our mutual...friend. It's bad, Sahra, I don't know what to do."
"Well, that's nothing new with her, right?" she whispered, taking a deep breath before marking the end of the pleasantries, "Please don't call me again."
・・・・・・・・・・・・・・・・・・・
Thanks for reading 🤍 [Febuwhump 2023 Masterlist]
@febuwhump
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erjmokay · 11 months
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Can someone give me an extra giant pillow cave to crawl into for a couple months please? I’m so, utterly fatigued.
So I had some sort of … event, occur today. Likely either some kind of non-convulsive seizure or a TIA (‘mini stroke’) or some other neurological malfunction. As terrified as I know I should be, since I have never experienced anything like this before in my life… I just, don’t have the time to think about it.
I’m dog-sitting tonight and tomorrow, I’ve got a ton of work to finish, my yearly self-eval is due tomorrow, our storage unit price doubles next month so we have to clear it out because we can’t afford everything on my income alone, my partner has a bike race coming up and surgery two days after that. We just got over covid a couple weeks ago, my other chronic illnesses are flaring because of it, and I simply do not have time for a new goddamn symptom or phenomena or whateverthefuck. So it will either have to not happen again, or wait its fucking turn for me to give a shit.
And tbh I’m leaving out some of the bigger stuff going on in my life rn cause again, I don’t have the time or energy to type it out into this void.
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queer-anarchist-rat · 5 months
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I'm tired of people saying "if you have ADHD to make tasks easier turn it into a game" especially as someone with limited brain function I can't just 'turn something into a game' because I don't have the mental capacity, AKA my brain doesn't understand HOW to do that
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blooming-grove · 2 years
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Dragon A Day 2022
Day 19: Favorite Skin/Accent - Ischemic!!
When i first joined the site it was my GOAL to get my hands on the Tender Grasp accent, and i'm lucky enough to have achieved it lol. At the time it seemed so unobtainable
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d0nutzgg · 9 months
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Understanding IHD with Data Science
Ischemic Heart Disease (IHD), more commonly recognized as coronary artery disease, is a profound health concern that stems from a decreased blood supply to the heart. Such a decrease is typically due to fatty deposits or plaques narrowing the coronary arteries. These arteries, as vital conduits delivering oxygen-rich blood to the heart, play a paramount role in ensuring the heart's efficient functioning. An obstruction or reduced flow within these arteries can usher in adverse outcomes, with heart attacks being the most dire. Given the gravity of IHD, the global medical community emphasizes the essence of early detection and prompt intervention to manage its repercussions effectively.
A New Age in Healthcare: Embracing Data Science
As we stand on the cusp of the fourth industrial revolution, technology's intertwining with every domain is evident. The healthcare sector is no exception. The integration of data science in healthcare is not merely an augmentation; it's a paradigm shift. Data science, with its vast array of tools and methodologies, is fostering new avenues to understand, diagnose, and even predict various health conditions long before they manifest pronounced symptoms.
Machine Learning: The Vanguard of Modern Medical Research
Among the myriad of tools under the vast umbrella of data science, Machine Learning (ML) shines exceptionally bright. An essential offshoot of artificial intelligence, ML capitalizes on algorithms and statistical models, granting computers the capability to process vast amounts of data and discern patterns without being explicitly programmed.
In the healthcare realm, the applications of ML are manifold. From predicting potential disease outbreaks based on global health data trends to optimizing patient flow in bustling hospitals, ML is progressively becoming a linchpin in medical operations. One of its most lauded applications, however, is its prowess in early disease prediction, and IHD detection stands as a testament to this.
Drawn to the immense potential ML holds, I ventured into a research project aimed at harnessing the RandomForestClassifier model's capabilities. Within the medical research sphere, this model is celebrated for its robustness and adaptability, making it a prime choice for my endeavor.
Deep Dive into the Findings
The results from the ML model were heartening. With an accuracy rate of 90%, the model’s prowess in discerning the presence of IHD based on an array of parameters was evident. Such a high accuracy rate is pivotal, considering the stakes at hand – the very health of a human heart. 9 times out of 10 the model is correct at its predictions.
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Breaking down the data, some correlations with IHD stood out prominently:
Moderate COPD (Chronic Obstructive Pulmonary Disease) – 15%: COPD's inclusion is noteworthy. While primarily a lung condition, its linkage with heart health has been a topic of numerous studies. A compromised respiratory system can inadvertently strain the heart, underscoring the interconnectedness of our bodily systems.
Diabetes – 18%: The correlation between diabetes and heart health isn't novel. Elevated blood sugar levels over extended periods can damage blood vessels, including the coronary arteries.
Age (segmented in quarterlies) – 15%: Age, as an immutable factor, plays a significant role. With age, several bodily systems gradually wear down, rendering individuals more susceptible to a plethora of conditions, IHD included.
Smoking habits – 14%: The deleterious effects of smoking on lung health are well-documented. However, its impact extends to the cardiovascular system, with nicotine and other chemicals adversely affecting heart functions.
MWT1 and MWT2 (indicators of physical endurance) – 13% and 14% respectively: Physical endurance and heart health share an intimate bond. These metrics, gauging one's physical stamina, can be precursors to potential heart-related anomalies.
Redefining Patient Care in the Machine Learning Era
Armed with these insights, healthcare can transcend its conventional boundaries. A deeper understanding of IHD's contributors empowers medical professionals to devise comprehensive care strategies that are both preventive and curative.
Moreover, the revelations from this study underscore the potential for proactive medical interventions. Instead of being reactive, waiting for symptoms to manifest, healthcare providers can now adopt a preventive stance. Patients exhibiting the highlighted risk factors can be placed under more meticulous observation, ensuring that potential IHD developments are nipped in the bud.
With the infusion of machine learning, healthcare is on the cusp of a personalized revolution. Gone are the days of one-size-fits-all medical approaches. Recognizing the uniqueness of each patient's health profile, machine learning models like the one employed in this study can pave the way for hyper-personalized care regimens.
As machine learning continues to entrench itself in healthcare, a future where disease predictions are accurate, interventions are timely, and patient care is unparalleled isn't merely a vision; it's an impending reality.
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naomiknight-17 · 9 months
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Since I've been studying medical terminology, I sometimes sprinkle it into my regular speech both for practice and fun. Because I am a nerd
So usually, if my brain is tired and I can't make coherent sentences, I would say "I can't do words" or something similar
But now I say "I am experiencing an acute transient aphasia" which basically means the same thing, but makes me practice science words
The other day I was visiting Mom's place, as I do at least twice a day every day to care for her diabetic cat, and I was really stressed and tired and couldn't keep up conversation
So I tried to use my phrase, but I was so foggy I just kept going "I'm having an acute... a transient... uh... transient..."
And Mom, who works in medical administration, goes
"... ischemic attack?"
"NO I AM NOT HAVING A STROKE!!"
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imposter syndrome is extra real when your work involves being the only person doing research on health disparities for one of the LARGEST health systems in the state, and thus potentially influencing decisions that can affect millions 🥴
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wisguy4567 · 1 year
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MEA Ischemic Heart Diseasemarket is experiencing a surge in sales across the globe, and it has been considerably boosted by technological advancement.
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cruelsister-moved2 · 2 years
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very dystopian to witness the exvangelicals who are like ‘the BITE model applies to organised religion inherently’ or something despite the fact that the guy who coined it is an observant conservative jew, bc thats easier than confronting the fact that like the overwhelming majority of american christianity is cultlike organisations operating, at their core, almost solely for profit 👍 
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mcatmemoranda · 2 years
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ABCD2: age, blood pressure, clinical features, duration of symptoms, and diabetes; DAPT: dual antiplatelet therapy (eg, aspirin and clopidogrel, or aspirin and ticagrelor); BP: blood pressure; SBP: systolic blood pressure; DBP: diastolic blood pressure. * Indications for long-term oral anticoagulation include embolism prevention for patients with atrial fibrillation, ventricular thrombus, mechanical heart valve, and treatment of venous thromboembolism.
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OA: oral anticoagulants; IVT: intravenous thrombolysis; MT: mechanical thrombectomy; NIHSS: National Institutes of Health Stroke Scale; DAPT: dual antiplatelet therapy (eg, aspirin and clopidogrel, or aspirin and ticagrelor). * Refer to text and associated algorithm for details. ¶ Brain and large vessel imaging, cardiac evaluation, and (for select patients) other laboratory tests. Δ For severe systemic or symptomatic intracranial bleeding, withhold all anticoagulant and antiplatelet therapy for one to two weeks or until the patient is stable.
Tx of Acute Ischemic CVA from UpToDate:
Immediate treatment– All patients with acute ischemic stroke should be evaluated to determine eligibility for reperfusion therapy with intravenous thrombolysis and/or mechanical thrombectomy, and aspirin and other antithrombotic agents should not be given alone or in combination for the first 24 hours following treatment with intravenous thrombolysis.
Otherwise, antiplatelet agents should be started as soon as possible after the diagnosis of transient ischemic attack (TIA) or ischemic stroke is confirmed, even before the evaluation for ischemic mechanism is complete. For most patients with no indication for long-term oral anticoagulation who have TIA (algorithm 2 [first algorithm above]) or ischemic stroke (algorithm 3 [second algorithm above]), we start antiplatelet therapy as follows:
•Aspirin alone – For patients with a low-risk TIA, defined by an ABCD2 score <4 (table 2), or moderate to major ischemic stroke, defined by a National Institutes of Health Stroke Scale (NIHSS) score >5 (table 3), we start treatment with aspirin (162 to 325 mg daily) alone.
•DAPT – For patients with a high-risk TIA, defined by an ABCD2 score ≥4 (table 2), or minor ischemic stroke, defined by a NIHSS score ≤5 (table 3), we begin with dual antiplatelet therapy (DAPT) for 21 days using aspirin (160 to 325 mg loading dose, followed by 50 to 100 mg daily) plus clopidogrel (300 to 600 mg loading dose, followed by 75 mg daily) rather than aspirin alone.
●Treatment by ischemic mechanism – Once the evaluation for TIA or stroke is complete, early antithrombotic therapy can be modified if necessary (algorithm 4 and algorithm 5) according to the ischemic mechanism:
•Atrial fibrillation – For patients with TIA or ischemic stroke who have atrial fibrillation, oral anticoagulation with warfarin or a direct oral anticoagulant (DOAC) is recommended for secondary stroke prevention. Oral anticoagulation can be started immediately for patients with TIA, and soon after stroke onset for medically stable patients with a small- or moderate-sized infarct and no bleeding complications or uncontrolled hypertension. For patients with large infarctions, symptomatic hemorrhagic transformation, or poorly controlled hypertension, withholding oral anticoagulation for one to two weeks is generally recommended.
•Intracardiac thrombus – For patients with acute cardioembolic TIA or ischemic stroke who have intracardiac thrombus in the left ventricle or associated with mechanical or native heart valves, we suggest early parenteral anticoagulation rather than aspirin (Grade 2C). This approach is controversial.
•No indication for anticoagulation – For most patients without atrial fibrillation or another indication for long-term oral anticoagulation, the initial antiplatelet regimen can be continued; for patients with low-risk TIA or moderate to severe stroke, we recommend aspirin monotherapy (160 to 325 mg daily) (Grade 1A). For patients with high-risk TIA or minor ischemic stroke, we recommend DAPT using aspirin and clopidogrel for 21 days rather than aspirin alone (Grade 1A).
However, certain additional modifications may apply:
-Carotid revascularization – Aspirin monotherapy is preferred by some experts prior to carotid endarterectomy, while DAPT is preferred by others. DAPT is recommended prior to and continuing for 30 days after carotid artery stenting.
-Intracranial large artery atherosclerosis – For patients with TIA or ischemic stroke attributed to intracranial large artery atherosclerosis stenosis of 70 to 99 percent, we suggest DAPT for 90 days.
-Dissection – The antithrombotic treatment of TIA or ischemic stroke caused by large artery dissection is discussed in detail separately.
●Long-term antiplatelet therapy – Beyond the acute phase of TIA and ischemic stroke, and in the absence of an indication for oral anticoagulation, long-term single-agent antiplatelet therapy for secondary stroke prevention should be continued with aspirin, clopidogrel, or aspirin-extended-release dipyridamole. Long-term DAPT with aspirin and clopidogrel is not recommended.
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glenngould-blog · 2 years
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Hailey Bieber Had a Mini-Stroke
Hailey Bieber Had a Mini-Stroke
Hailey Bieber recently had a mini-stroke (TIA). Here’s what you need to know. DID YOU KNOW THAT STROKES AMONG YOUNG INDIVIDUALS are not uncommon? The recent health scare of Hailey Bieber (an American model, media personality, socialite, and wife of musician Justin Bieber) is raising awareness about strokes. Hailey Bieber opens up about her mini-stroke: “It was definitely an eye-opening thing…
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ricisidro · 11 days
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The latest data from the Philippine Statistics Authority (PSA) showed that most of the leading causes of death in the Philippines (Jan - Oct 2023), even in the previous year (Jan - Oct 2022), are considered noncommunicable diseases (NCDs).
And the top 3 causes of death were ischemic heart diseases, neoplasms (cancers) and cerebrovascular diseases.
https://psa.gov.ph/statistics/vital-statistics/node/1684062618
Dr. Tony Leachon
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pressnewsagencyllc · 16 days
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COVID-19 shatters decades of global health progress, slashing life expectancy
A recent study published in The Lancet presented the global burden of 288 mortality causes and life expectancy decomposition. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has been analyzing causes of human death for over three decades, which has been used to guide policies, monitor/assess health interventions, and reduce risk factors. Assessing cause-specific mortality…
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runawaywidow · 19 days
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18 Surprising Stroke Facts that I Didn't Know, Until Now
The lullaby music is playing again. So sweet. “Are they trying to make the patients fall asleep?” I smiled at the nurse as she entered the room. “No, that means a baby has just been born,” she replied as she turned off Pete’s call button. We returned to Sarasota Memorial Hospital exactly 5 days after being discharged from my husband’s neck surgery for a cervical spinal fusion. He had been…
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