#colorectal cancer

[mindblowingscience]

Mutating cells can prevent the spread of cancer by flipping themselves into a state of reduced activity called senescence. Cancer genes, however, can retaliate by reviving those cells so they can replicate again.

The mechanism for reviving senescent cells, sometimes called zombie cells, was only partially understood. Now, a new study in the journal Cell Genomics traces the process in colorectal cancer cells. Researchers believe the process is similar in other tumor types.

���Once a cell starts to become cancerous, it begins replicating very quickly, and that triggers senescence,” says lead author Ricardo Iván Martínez-Zamudio, assistant professor of pharmacology at the Robert Wood Johnson Medical School at Rutgers University. “Once the cell becomes senescent, however, it often begins making a particular protein that helps it emerge from senescence.

“The next stage in the research is to see if medications can target this protein. We want to find a substance that will bind to it and prevent it from binding with other proteins, so these cells stay in senescence and don’t reproduce.”

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#science #stem #health #medicine #cancer #colorectal cancer

[bpod-bpod]

Colon Cancer Colony

A distinct group of Fusobacterium nucleatum bacteria, microbiome resident of the mouth but uncommon in the normal lower gut, is predominant in human colorectal cancers

Read the published research article here

Image from work by Martha Zepeda-Rivera and colleagues

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature, March 2024

You can also follow BPoD on Instagram, Twitter and Facebook

#science #biomedicine #biology #microbiome #colorectal cancer

[cbirt]

There is a growing number of incidences of colorectal cancer in people under the age of 50 (EOCRC), but the intrinsic molecular mechanisms underpinning it are not very well understood. A recent study was conducted on 79 CRC patients of Chinese ancestry to understand the differences in the omics of EOCRC compared to general CRC. The study presents incredible findings and shows that EOCRC has many tumor mutations, increased DNA repair features, and upregulated immune infiltration. The authors also discovered a potential biomarker, LMTK3, that may functionally drive EOCRC development and immunotherapy. The study also provides crucial information for precision oncology in treating EOCRC.

Colorectal cancer is a type of cancer that affects the colon and rectum. It is the third most common cancer type and the second most deadly, and therefore significantly impacts global health. While developed countries have seen a decrease in colorectal cancer cases due to advancements in cancer screening/diagnosis technology, there has been a rise in early-onset colorectal cancer (EOCRC), particularly in China, making it an issue that must be addressed.

Various established risk factors for late-onset colorectal cancer (LOCRC) comprise consumption of a Western-style diet, obesity, physical inactivity, and molecular alterations in driver genes of APC, TP53, and KRAS. However, patients with EOCRC possess distinct features compared to those with LOCRC, including male predominance, less environmental exposure accumulation, a history of inflammatory bowel disease or a family history of colorectal cancer, and tumors on the left side with molecular and genetic heterogeneity.

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#bioinformatics #omics #colorectal cancer

[eazy-peazy54]

hey chat kinda serious post today but uh

along with it being women's history month, it is also colorectal cancer awareness month!

march is always very important to me, because my mom has had stage four colorectal cancer for about six years now.

back in 2018, they gave her 6 months to live, but through many surgeries, and many many rounds of chemo, she is still standing, and living her best life today!

so fuck cancer, and tell someone who has colorectal cancer, (or who has a relative/knows someone who has it) you love em!

also get a colonoscopy 💙

#colorectal cancer #cancer #cancer awareness #colorectal cancer awareness #colorectal cancer awareness month #awareness #💙 #colon cancer

[contentment-of-cats]

Labs day.

Let's spin the wheel on how many tubes of blood come out.

#cancer #cancer survivorship #remission #health #schrodinger's cancer #colorectal cancer #get your colonoscopy because years of fecal smears didn't catch mine

[gastroenterologist]

Uncover the causes, symptoms, and diagnosis of gastrointestinal bleeding. Learn about this critical medical condition for prompt intervention.

#abdominal pain #Anemia and GI Bleeding #Blood in Stool #Blood Tests for GI Bleeding #Capsule Endoscopy #Causes of Gastrointestinal Bleeding #colorectal cancer #Colorectal Polyps #Diagnosing Gastrointestinal Bleeding #Gastrointestinal #Diverticulosis #Dizziness or Fainting #endoscopy #gastroesophageal #Gastrointestinal Bleeding #GI Bleeding #Inflammatory Bowel Disease

[ciendoscopy]

Early on-set colorectal cancer is becoming more and more common in people who are too young to qualify for a colonoscopy. This kind of cancer can be difficult to detect without the appropriate screenings, especially since this topic can be embarrassing to talk about for many young people. Central Illinois Endoscopy Center wants to provide you with the resources to stay healthy and feel supported so these important topics can be discussed openly.

#centralilendoscopycenter #colonoscopy #colorectal cancer #ciecblog

[gastroenterologistpretoria]

Colon Cancer Awareness: Detecting the Signs and Taking Action

Colorectal cancer, often known as colon cancer, is a common and potentially fatal disease that affects the colon and the rectum. It is a form of cancer that starts in the colon (large intestine). Colon cancer most commonly affects older persons, although it can strike anyone at any age. The colon is the last section of the digestive tract. Polyps, which are tiny, noncancerous (benign) collections of cells that grow on the inside of the colon, are the most common starting point. Some of these polyps can develop into colon cancer over time. It is the third most frequent cancer in both men and women worldwide, emphasizing the importance of increasing awareness and early identification. However, if diagnosed early, colon cancer is extremely curable and generally prevented. 

#colorectal cancer #colorectal surgeon #colon cancer

[lexi-anastasia-astra-luna]

Warning; goes into what symptoms the cancer has so don’t read the red if you don’t want to know!! (Sorry this is so long. I waffled. Hope it makes sense).

In honor of Kevin Conroy who voiced the brilliant Batman and Chadwick Boseman who brought to life T’challa, the black panther, who both sadly passed away from Colorectal cancer. Please get yourselves checked. You are more likely to survive this fuckin disease if you catch it early enough.

So many others have died from this; the beautiful Audrey Hepburn and Bobby Moore the English football captain and 1966 World Cup winner. He even has a a fund; the Bobby Moore fund for Cancer Research UK. They are committed to beating bowel cancer in his memory.

Please if you believe you or someone you know have any issues or have some symptoms then please go to the doctors and get checked out. (Eg; bad constipation, blood in the stool, loss of appetite, loss of weight, nausea or vomiting, in someone over 50 years old). They say that half of individuals with colorectal cancer do not report any symptoms.

There are charities that want to help find a cure for any cancer, however there are ones who have specific cancers in mind. So if you have some money to spare, even a pound or a dollar etc than please think of donating it to these charities.

Seen as this is in particular for 2 wonderful heroes, find a charity that when you donate money to them, they are helping/working with people who have colorectal cancer. Whether it is money that goes towards funding to try and find a cure or going to homes or people who have the horrible disease and trying to help them live their life.

I hope Chadwick welcomed his fellow hero in the stars and now they can act out some great DC vs Marvel, Batman vs Black Panther for those in the stars with them. Hopefully one day this disease will be beaten. Enjoy the stars Kevin⭐️

#sorry if this doesn’t make sense #I haven’t slept in days #plus my pain meds aren’t working #fuck cancer #kevin conroy #tv show #batman #bruce wayne #batman the animated series #colorectal cancer #cancer #charity #charities #funds #chadwick boseman #the black panther #black panther #t’challa #rest in peace kevin conroy #in the stars #rip chadwick boseman #movies #superheroes #superhero #hero #heroes #celebrity deaths

[sumayarahman]

Chemo o’clock

Cycle 3

#chemotherapy #cancer #fuck cancer #chemo #fashion #peace #hospital #love #folfox #colorectal cancer #stage 3

[kaizenhospitals]

What is Colorectal Cancer?

Colorectal cancer is a neoplastic disease of the large intestine from Ileo-cecal junction till the rectum. Unregulated growth of their cell lining lead to polyps and cancers.

The exact cause of colorectal cancer is not known, but several factors can increase risk of developing colorectal cancer.

Age: Elderly people are at risk of colorectal cancer. It is most common in people over 50 years of age.

Family history: People with history of colorectal cancer in family (first degree relatives) are at increased risk. 

Genetic factors: They are associated with some hereditary syndromes like lynch syndrome, familial Adenomatous polyposis, etc.

Lifestyle factors: A diet rich in red and processed meats and low in fibres or lacking fruits and vegetables can increase risk of colon cancer. Obesity, reduced physical activity, alcohol consumption or smoking also increase risk of colorectal cancer.

Medical Conditions: Certain medical conditions like inflammatory bowel disease (Crohn’s disease and ulcerative colitis) can increase the risk of colorectal cancer.

It is important to note that having one or more risk factors does not mean that a person will develop cancer. Regular screening tests such as stool occult blood and colonoscopy, can help to detect as well as prevent it at the early stage. 

#Colorectal cancer #colon cancer #colorectal cancer #bowel cancer #sigmoid colon #rectal cancer #colorectal #stage 4 colon cancer #colon cancer treatment #adenocarcinoma colon #stage 4 bowel cancer #malignant neoplasm of colon #colon health #colorectal cancer treatment #bowel cancer treatment #the colon #colorectal carcinoma #rectal cancer treatment #rectal adenocarcinoma #sigmoid cancer #large intestine cancer #colonic neoplasm #rectal tumor #colon tumor #carcinoma colon #colorectal adenocarcinoma #large colon #cancer intestinal #colon rectum #sigmoid colon cancer

[falseandrealultravival]

The Life of a Blog (Poetry)

(This picture is the original picture of the icon of another blog I'm doing in Japan. The Black-yellow figure.)

I’m updated daily

the blog itself

there is someone who makes me write

he is immortal.

So when I stopped updating

Only the blog will die then.

day by day

The updated blog is--

How do you carry the shadow of the immortal

It would be interesting to ask yourself

it's like walking in life

Some blogs are loved to death.

ブログの一生（詩）

私日々更新される

ブログそのもの

私を書かせる者がいるが

その者は不死である。

だから、私が更新されなくなった時

その時はブログのみ死ぬのだ

日々一枚一枚と

更新されるブログは――

いかに不死の者の影を宿しているのか

自問しても面白いだろう

それは人生の歩みにも似ている

死んでも愛されるブログもある。

I wrote a poetry about the impermanence that I recently felt after being treated for colorectal cancer, which is surprisingly cool. In this poetry, I am writing as a blog ≒ blogger. "Sentences are people."

(2016.12.08)

#The Life of a Blog #blog #immortal #death #impermanence #colorectal cancer #blogger #Sentences are people. #poetry

[bpod-bpod]

Revelation Revolution

Whole-body positron emission tomography (PET) one hour after injection of radioactive glucose highlights rapidly metabolising tissue such as the liver metastases of a colorectal tumour seen here within the abdomen, along with normal accumulation of the tracer in the heart, bladder, kidneys and brain

Edward J Hoffman – born on this day, January 1st in 1942 – along with Michel Ter-Pogossian and Michael E. Phelps – developed the first human Positron Emission Tomography scanner in 1973

Movie adapted from PET scan GIF created by Jens Maus

Video in the Public Domain

You can also follow BPoD on Instagram, Twitter and Facebook

#science #biomedicine #biology #medical imaging #colorectal cancer #metastasis #liver #PET scan #positron emission tomography #born on this day

[mceproductions]

No words except a crappy photoshop job as a tribute. Billy Kametz it wont be the same without you. Shields Up to everyone going through this .

#billy kametz #naofumi iwatani #shields up #the rising of the shield hero #shield hero #naofumi x raphtalia #filo #colorectal cancer #rip #I am Ferdinand

[mypatchworkreflection]

Warning, there's pics of an endoscopy scans in the article. Worth reading though, this is huge!

#cancer #endoscopy #medicine #colorectal cancer

[lamajaoscura]

#ryan reynolds #colonoscopy #colorectal cancer #rob mcelhenney