The Component of cell undergoes a variety of changes responding to cell injury, and may or may not lead to cell death.
The Component of cell undergoes a variety of changes responding to cell injury, and may or may not lead to cell death.
Cell injury and death .pdfDownload
Injurious stimuli trigger the process of cellular adaptation, whereby cells respond to withstand the harmful changes in their environment.
Overwhelmed adaptive mechanisms lead to cell injury. Mild stimuli produce reversible injury. If the…
hot take, heavily penalizing teenagers for causing each other head injuries, even unintentionally, is good, actually, and the nhl could stand to take a page from the iihf book on the way that standard is upheld (for all ages).
“how are you gonna prepare them for the nhl if the rules are different?!” this is not an nhl run event. this is not the george parros department of player safety or the gary bettman league. this is not the ‘nhl prospect practice and preparation tournament’, this is the world junior hockey championship. it is its own entity unto itself and for its own ends, it is not just a stepping stone for your favourite budding superstars to gain prestige and fanfare before they move on to the only “big league” that north american hockey fans consider significant or meaningful. it plays a larger role in the development of not only players, but also of entire hockey training programs in countries where hockey, even men’s hockey, is an under-funded or less established sport.
not all of these kids are going to go on to be nhl players. ALL of them should get the chance to grow up to be adults who don’t have their quality of life degraded by lingering head injuries and cte.
If… If Fukuzawa dies here… What if he transfers his ability to Ranpo in his last minutes of life just like Kyoya’s mother did for her…?
bsd does love its thematic parallels after all…
Without Fukuzawa’s ability, the ADA would be severely disadvantaged. And Ranpo just so happens to be there within reach and doesn’t already have an ability himself.
Bonus points if Fukuchi and Fukuzawa end up simultaneously killing each other, and go out like Oda and Gide did.
Fukuchi and Fukuzawa can both deal each other a final killing blow. Fukuzawa collapses and Ranpo runs over to hold him as he dies, just like Dazai did for Oda. Fukuzawa transfers his ability to Ranpo, then dies.
Kunikida can finish this arc being the new leader of the ADA, while Ranpo has to deal with still needing to be the ADA’s main strategist all while dealing with his grief.
Oof! Papercut. When you damage your skin, you sever the dense network of nerve fibres in your biggest organ. These nerves sense pain, temperature, and itching, which helps keep you safe. When these fibres snap, your body breaks them down, producing cellular debris that must be cleared for new nerve fibres to grow. Despite the importance of this process, we haven't understood its mechanisms – until now. By plucking scales from zebrafish skin and following the repair process in living animals, scientists have uncovered the cellular details of this cleanup operation. Here, we see immune cells called Langerhans cells (blue) hoovering up nerve fibre debris (pink). This new role for Langerhans cells was completely unknown and has important clinical implications. Previous research has found that nerve damage disorders caused by diabetes and cancer chemotherapy are linked to changes in the number of skin Langerhans cells – targeting them could lead to new treatments.
Written by Henry Stennett
Video from work by Eric Peterman and colleagues
Department of Biology, University of Washington, Seattle, WA, USA
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in Disease Models & Mechanisms, April 2023
You can also follow BPoD on Instagram, Twitter and Facebook
If I have something akin to a special interest I think it must be radiation sickness and the incidents/accidents/disasters that cause it
The Goiana Incident. The Radium Girls. Three Mile Island. Chernobyl. The Demon Core. The SL-1. The Therac-25. I could go on
I don't know what it is but reading and watching everything I possibly can on the science behind, the causes of, and end results of radiation-related incidents is absolutely fascinating to me
I hate blood and gore and injury but if an article or video shows what radiation does to someone's skin or bone marrow? I am studying that shit
You had tried to count the days at first. It was hard but at the time, you still had hope that you wouldn’t be here for long. That hope was all but gone now but you still counted. It was pretty much the only thing that you could do.
Your cell was small, with just enough space for you to stretch out in the center and not touch any of the walls but that was it. The clear sides of it surrounded you and allowed you to have a 360° view of the larger room containing your cell. The large room was massive, so massive you couldn’t see the end in any direction you looked, and it was full of similar cells as yours. They came in all different shapes and sizes, each containing a single thing. You knew that there were other living creatures somewhere around you, you could hear them, but you couldn’t see any of them. There were just plants and artifacts around you, an interesting selection of things that seemed both alien and not. The strange glowing red flower across from you didn’t seem to be anything that was from earth — unless it was from under the ocean or from Australia — but the baseball right next to you was a signed Babe Ruth one.
It was incredibly boring, to be honest. You had only seen two people the entire time you’d been here — a strange purple alien came by occasionally to clean the outside of the cells but they never talked to you, or even made eye contact. The other was a very flamboyant man that liked to monologue at you. It used to fill you full of fury whenever he came by but it had been close to a year since you’d been taken.
You just wanted the company now.
He, The Collector, had started out trying to talk to you every day. You had injured yourself in those first days, screaming yourself hoarse in mad fury and throwing yourself physically at the cell wall nearest to him, blooding your fists against the clear material that held you captive. The Collector always left you alone for a couple of days in between those visits, allowing your fury to lessen and your injuries to heal, the food he had transported into your cell seemingly helping you heal faster.
You thought it took you a couple of months before you started to ignore him when he came by. You would sit pointly with your back to him, turning around to never face him. It didn’t stop him from talking but you could hear the annoyance in his voice when you did and those days tended to end with him stomping off in a huff.
It brought a smile to your face when he did so.
It was only in the last month or so that you started to talk, actually talk, back to The Collector. You had felt yourself going stir crazy and he was the only thing around you that changed — you grasped it like a lifeline.
He was an interesting character. He skipped around topics when he was talking, never staying on one for too long, and sometimes it was hard to follow his train of thought. But, since you started talking with him, The Collector could stay and talk for hours, the two of you bonding over the strangest topics. He seemed to like listening to you answer his many questions about earth and, as this gave you a chance to talk without sounding crazy, you strive to answer anything he asked.
Your days were monotonous and boring, a never ending realm of grey so The Collector tended to stand out.
You still counted the days since you’d been taken but you feared you were now counting for the wrong reasons. No longer keeping track of how long you’d been gone but how long it’d been since you’d had company.
@febuwhump
A/N — any blank blogs that follow me are going to be reported then blocked. Pick a different profile pic and get a witty header or something.
Thinking about Erik snapping at Charles with “well maybe you should have fought harder for them” and the pain in his eyes when Charles told him they didn’t want the same things.
The experiment involved little blobs of human brain stem cells tissue transplanted into rats. Then neurons integrated into the rat's brain so well the organoids started to respond to visual stimuli made of black and white images.
The experiment stopped after 3 months because of the rat rejecting human tissue despite the immunosuppressant medication.
The next experiment is to transplanting human brain tissue into adult rats with large cortical injuries, to see if they, too, can show functional integration
Brain organoids created from human pluripotent stem cells represent a promising approach for brain repair. They acquire many structural features of the brain and raise the possibility of patient-matched repair. Whether these entities can integrate with host brain networks in the context of the injured adult mammalian brain is not well established.