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#Molecular Biology
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Unlocking new avenues for curing cancer: Cell receptor neuropilin-1 could hold the key
Unlocking new avenues for curing cancer: Cell receptor neuropilin-1 could hold the key
Cancer is an insidious disease that, despite being around for centuries, is still very difficult to diagnose and treat. Thus, cancer has been the focus much research in the biomedical fields. Today, with research methods advancing rapidly and the base pool of researchers growing constantly, our fundamental understanding of the mechanisms of cancer formation and proliferation have increased, and…
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Wastewater surveillance to monitor COVID-19 starts in Osaka Prefecture
Wastewater surveillance to monitor COVID-19 starts in Osaka Prefecture
On April 15, 2021, Hokkaido University and Shionogi & Co., Ltd. will start to monitor COVID-19 in Osaka Prefecture based on wastewater-based epidemiology (WBE), with the cooperation of the Prefectural Government. The joint project aims to carry out quantification and genetic analysis (variant/mutation detection) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in wastewater for…
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TGen identifies gene that could help prevent or delay onset of Alzheimer's disease
TGen identifies gene that could help prevent or delay onset of Alzheimer’s disease
PHOENIX, Ariz. — April 13, 2021 — Findings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that increasing expression of a gene known as ABCC1 could not only reduce the deposition of a hard plaque in the brain that leads to Alzheimer’s disease, but might also prevent or delay this memory-robbing disease from developing. ABCC1, also known…
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New assay detects marker of metastatic cancers, infection, trauma and neurological disease
New assay detects marker of metastatic cancers, infection, trauma and neurological disease
Scientists at the Walter Reed Army Institute for Research demonstrated the potential of a novel blood test for cathepsin B, a well-studied protein important to brain development and function, as an indicator for a range of disease states. Cathepsin B plays an important role in the body, regulating the metabolism, immune responses, degradation of improperly produced proteins and other functions.…
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Scientists reveal COVID-19 news, next frontier in fighting substance abuse, more
Scientists reveal COVID-19 news, next frontier in fighting substance abuse, more
Contact: media@experimentalbiology.org Want to find out the latest insights into COVID-19, explore new medicines for fighting substance abuse or delve into cultural challenges facing the scientific community? The Experimental Biology (EB) 2021 meeting is your source for the latest research and discussion on today’s hot topics in science and medicine. EB 2021, to be held April 27-30, is the annual…
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bored-sixthformer · 3 days ago
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another post back-to-back
i didn't know if i wanted to put this in the introductory post so i'm making a separate post!
the title is derived from the atomic mass of sodium, as well as being the number after 22. the term 'catch-22' refers to a paradoxical or difficult problem that requires further thought, hence the theme of this blog to carry out debates from philosophical to purely scientific in nature!
so that's the title ig lolll
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Pain receptors linked to the generation of energy-burning brown fat cells
Pain receptors linked to the generation of energy-burning brown fat cells
BOSTON – (April 12, 2021) – A new source of energy expending brown fat cells has been uncovered by researchers at the Joslin Diabetes Center, which they say points towards potential new therapeutic options for obesity. According to the new report, published today by Nature Metabolism, the key lies in the expression of a receptor called Trpv1 (temperature-sensitive ion channel transient receptor…
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Activating the brain's immune system against cancer prevents it from spreading
Activating the brain’s immune system against cancer prevents it from spreading
Groundbreaking research from Tel Aviv University may lead to a significant breakthrough in the battle against deadly brain cancer. To begin with, the researchers identified a failure in the brain’s immune system, leading to the amplification of cell division and spread of Glioblastoma cancer cells. The failure results partially from the secretion of a protein called P-Selectin (SELP), which, when…
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Research shows cytonemes distribute Wnt proteins in vertebrate tissue
Research shows cytonemes distribute Wnt proteins in vertebrate tissue
Scientists have made a pivotal breakthrough in understanding the way in which cells communicate with each other. A team of international researchers, including experts from the University of Exeter’s Living Systems Institute, has identified how signalling pathways of Wnt proteins – which orchestrate and control many cell developmental processes – operate on both molecular and cellular…
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New study explains Mycobacterium tuberculosis high resistance to drugs and immunity
New study explains Mycobacterium tuberculosis high resistance to drugs and immunity
A consortium of researchers from Russia, Belarus, Japan, Germany and France led by a Skoltech scientist have uncovered the way in which Mycobacterium tuberculosis survives in iron-deficient conditions by utilizing rubredoxin B, a protein from a rubredoxin family that play an important role in adaptation to changing environmental conditions. The new study is part of an effort to study the role of…
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EcoR1 is an endonuclease restriction enzyme derived from E. coli; it's used to cut DNA helices at the recognition sequence G/AATTC for lab procudures such as cloning and in vitro DNA screening/deletion. It leaves a 5' overhang of 4 nucleotides (AATT) called a 'sticky end' which is useful for the binding of DNA during ligation reactions in plasmid reconstructions.
It's a 4 nucleotide overhang instead of 5 because the restriction site is palindromic: the restriction site G/AATTC and the complimentary strand CTTAA/G, when aligned, have 4 nucleotides in between the breaks.
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Inheriting acquired traits requires trailblazer modifications to unfertilized eggs
Inheriting acquired traits requires trailblazer modifications to unfertilized eggs
An epigenetic study at the RIKEN Center for Integrative Medical Sciences shows that in mouse egg cells, modifications to histone H2A at lysine 119 lay the groundwork for inherited DNA functional modifications from the mother. In books and the movies, a group of people on a special mission always sends out a scout to do reconnaissance before they proceed. Sometimes, the scouts leave signs or…
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fishystudies · 8 days ago
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playing around with image j and I made a cool animation from my z stack! this is a pectoral fin from a transgenic fli1a:eGFP double homozygous mutant. this transgene helps visualize vasculature. actinodin mutants such as this one have defects in their fin rays, and given that vasculature develops in conjunction with the fin rays, the vessels may exhibit defects as well. it looks like that’s what’s happening here! 
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biotechtimes · 10 days ago
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AIIMS Bathinda Jobs 2021 – Biotech / Biochem / Life Sciences Vacancy
New Post has been published on https://biotechtimes.org/2021/04/05/aiims-bathinda-jobs-2021-biotech-biochem-life-sciences-vacancy/
AIIMS Bathinda Jobs 2021 – Biotech / Biochem / Life Sciences Vacancy
AIIMS Bathinda Jobs 2021
AIIMS Bathinda Jobs 2021 – Biotech / Biochem / Life Sciences Vacancy. All India Institute of Medical Sciences, Bathinda has announced a JRF job notification. Interested candidates can check out the complete job details below:
Department of Biochemistry All India Institute of Medical Sciences, Bathinda
Applications are invited for one post of Junior Research Fellow in SERB-DST sponsored project entitled “To evoke Transplanted Stem cell Survival against Ischemic/Reperfusion injury through Pharmacological Preconditioning with Phosphodiesterase Inhibitors“, purely temporarily. The details of the post are as follows:
Name of Post: Junior Research Fellow (JRF)
Tenure of the Post: Up to one & a half-year
Fellowship Amount: Rs 31000/- per month + HRA (as per norms of funding agency)
Essential Qualification:
Post Graduate degree in Biochemistry / Biotechnology / Molecular Biology / Life Science
At least 60% marks or equivalent
Nation level exam (NET/JRF/GATE) qualification.
Desirable Qualification: Experience in Cell culture, Flow Cytometry & Real-time PCR.
How to apply: Soft copy of application/Covering Letter and CV (with photograph mentioning: full details of academic qualification, research experience, telephone/mobile number, e-mail address) and scanned copies of experience and educational qualification may be sent to the undersigned by 15 th April 2021 (till 5.00 PM) through e-mail (kumar.sanjay11@aiimsbathinda.edu.in / sanjayaiims@gmail.com) only.
After screening the applications, only the candidates found suitable to attend the interview will be intimated via email before 16 th April 2021. The PI/Screening Committee’s decision to call only the most suitable candidates will be final and no correspondence in this regard will be entertained.
Candidates may appear for the interview at the meeting room, Ayush Block, AIIMS Bathinda on 19th April 2021 at 09:00 AM. Information and further updates will also be available on the website www.aiimsbathinda.edu.in
Note:
The above post is purely temporary for sanctioned project and duration.
No T.A/D. A or any other allowances will be paid for attending the interview.
Fellowship may be cancelled at any time in case of any misconduct, unsatisfactory research work or if fellow is found ineligible later.
The rules and regulations of AIIMS and/or funding agency (DST) will be applicable on the selected candidate.
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Myositis-specific autoreactive T cells are pathogenic for dermatomyositis
Myositis-specific autoreactive T cells are pathogenic for dermatomyositis
Tsukuba, Japan – Dermatomyositis is an idiopathic inflammatory myopathy that has been regarded as an autoimmunity-based disorder, although its pathogenesis remains unclear. In this study, researchers from the University of Tsukuba used a mouse model to identify a mechanism by which dermatomyositis may develop in humans. The animal model and findings can be used to better understand the disease…
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Structural biology opens new perspectives for treating psychiatric disorders
Structural biology opens new perspectives for treating psychiatric disorders
(European Molecular Biology Laboratory) Employing innovative technologies for combining data from hundreds of crystals, scientists determined the molecular structure of Glycine Transporter 1, a protein that modulates neuronal activity in the brain. The revealed binding sites through which the transporter can be inhibited by drugs. This could open new avenues for developing psychiatric drugs. The…
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