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Unlocking new avenues for curing cancer: Cell receptor neuropilin-1 could hold the key
Unlocking new avenues for curing cancer: Cell receptor neuropilin-1 could hold the key
Cancer is an insidious disease that, despite being around for centuries, is still very difficult to diagnose and treat. Thus, cancer has been the focus much research in the biomedical fields. Today, with research methods advancing rapidly and the base pool of researchers growing constantly, our fundamental understanding of the mechanisms of cancer formation and proliferation have increased, and…
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New way of diagnostics detects 'undetectable' genetic defects
New way of diagnostics detects ‘undetectable’ genetic defects
Detecting hidden genetic defects by applying an existing method to an existing datasets. Researchers at Radboud university medical center have succeeded: they showed that the ‘Expansion Hunter’ method can detect errors in the DNA that lead to repeat expansion diseases, such as the movement disorder ataxia. This result provides guidance to fellow researchers worldwide on how to use this method to…
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lunarleigh · a day ago
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I am waking up with an extreme feeling of dread this morning. Maybe it’s because I wasted a valuable hour and a half of my time and money with a quack nutritionist.
Maybe it’s all the things she told me, that I could have additional hormonal issues that need to be balanced, that I could have heavy metal toxicity causing all my issues and pain, or I could have lymes that has been missed for years, maybe even my whole life.
She sunk the ship of my current plan of exercise, rest, water, vitamin d, stretching and resting when my body needs it and going to the doctor when something new feels off and said she will rescue me with her plan including nutrition, detoxification, diagnostics and supplements. She didn’t even do any tests and she is cookie cutter labeling me with so many issues.
I guess the consultation wasn’t a total waste. I have interesting news for my doctor at my next visit and I should probably stop vaping, (my dirty little secret) because if I have any issues with metals, smoking for many years in the past, and now vaping seem to be easy enough to blame.
Even though after checking with dr Google, metal toxicity is rare and the only thing I would do for it is some type of elimination detox. The other option mentioned is described as dangerous and possibly ineffective with a side effect of death.
I could also ask my dr at my next follow up to retest me for Lymes, see if he can test me for metals or know of someone who could and ask where I could go for more thorough hormone testing then my gynocologist has done in the past. I wonder what he will say.
Feeling of dread part 2. My son is starting in school instruction again so soon. I feel like I barely thought it through. He needs his teachers though, he has said that more than once in the past year. I just hope it was the right decision at the end of the day.
Maybe I could have looked harder for a tutor before going back into the building. I hope his anxiety doesn’t get the best of him when we start going back. My poor sweetie gets the worst worry stomach aches.
I feel like I’ve been stumbling through this whole week. I had a productive Monday and Tuesday at work followed by a day full of distraction and lack of focus. I’m toward the bottom of our team’s point board for the month, which never makes me feel good.
The loud construction and the aggravation of the damage to my car last week really threw off my game, and yesterday it was dealing with trying to make the school transportation and my work and PT schedule work together in a way that I might not feel like a zombie by July.
Thanks for reading my morning rant. ☕️
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Expert reviews discuss key topics in bone disorders and chronic kidney disease
Expert reviews discuss key topics in bone disorders and chronic kidney disease
Metabolic bone disease is a common complication of chronic kidney disease (CKD) and involves a broad spectrum of disorders of mineral metabolism that result in both skeletal and extra-skeletal consequences. A new special issue of Calcified Tissue International brings together a comprehensive series of state-of-the-art reviews which discuss key issues in CKD and mineral and bone disorders, known…
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sandlerresearch · 9 days ago
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Molecular Diagnostics Market by Product & Service (Reagents, Kits, PoC & Tabletop Instruments), Application (COVID-19, Hepatitis, HAI, HIV, Oncology, Genetic Tests), Technology (PCR, NGS, ISH), End User (Hospitals, Diagnostic Labs) - Global Forecast to 2026 published on
https://www.sandlerresearch.org/molecular-diagnostics-market-by-product-service-reagents-kits-poc-tabletop-instruments-application-covid-19-hepatitis-hai-hiv-oncology-genetic-tests-technology-pcr-ngs-ish-end-us.html
Molecular Diagnostics Market by Product & Service (Reagents, Kits, PoC & Tabletop Instruments), Application (COVID-19, Hepatitis, HAI, HIV, Oncology, Genetic Tests), Technology (PCR, NGS, ISH), End User (Hospitals, Diagnostic Labs) - Global Forecast to 2026
“Increasing prevalence of infectious diseases and cancer and the rising funding for R&D are driving the overall growth of the molecular diagnostics market”
The global molecular diagnostics market size is projected to reach USD 31.8 billion by 2026 from USD 17.8 billion in 2021, at a CAGR of 12.3% during the forecast period. Market growth is driven by factors such as the increasing prevalence of infectious diseases and cancer, the rising funding for R&D, the increase in PoC testing devices and technological advancements. On the other hand, an unfavorable reimbursement scenario and the high cost of instruments is expected to limit market growth to a certain extent in the coming years.
“The reagents & kits accounted for the highest growth rate in the molecular diagnostics market, by product & service, during the forecast period”
The molecular diagnostics market is segmented into reagents & kits, instruments and other products. The reagents & kits segment accounted for the highest growth rate in the molecular diagnostics market in 2020. The requirement reagents & kits in large numbers compared to instruments is the main factor contributing to this segment’s high growth rate. This segment’s market growth can also be attributed to repeat purchases of reagents & kits compared to instruments.
“Infectious Disease Diagnostics segment accounted for the highest CAGR”
Based on the application, the molecular diagnostics market is segmented into infectious disease diagnostics, oncology testing, genetic tests and other applications. In 2020, the oncology testing segment accounted for the highest growth rate. Increasing incidence of cancer, technological advancements, and development of personalized medicine and companion diagnostic assays are the major factors driving this segment’s growth.
“Diagnostic Laboratories segment accounted for the highest CAGR”
Based on end-users, the molecular diagnostics market is segmented into diagnostic laboratories, hospitals and clinics and other end users. In 2020, the diagnostic laboratories segment accounted for the highest growth rate. This can be attributed to increased test volume of infectious diseases and cancer and strengthening healthcare infrastructure for efficient disease diagnosis and treatment.
“Asia Pacific: The fastest-growing region molecular diagnostics market”
The global molecular diagnostics market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. The Asia Pacific region is projected to register the highest CAGR during the forecast period. Factors such as the government efforts to increase awareness about the early detection of diseases and regular health check-ups; continuously rising healthcare expenditure; increasing number of hospitals and diagnostic laboratories in India and China; and strengthening research base for diagnostic procedures across India, China, and Japan are driving the growth of the molecular diagnostics market in this region.
The primary interviews conducted for this report can be categorized as follows:
By Company Type: Tier 1 – 20%, Tier 2 – 45%, and Tier 3 – 35%
By Designation: C-level – 30%, D-level – 20%, and Others – 50%
By Region: North America – 36%, Europe – 25%, Asia Pacific – 27%, Latin America – 9% , and the Middle East & Africa – 3%
Lits of Companies Profiled in the Report:
F. Hoffmann-La Roche Ltd. (Switzerland)
Hologic, Inc. (US)
bioMérieux SA (France)
Abbott Laboratories (US)
QIAGEN (Netherlands)
Thermo Fisher Scientific Inc. (US)
Illumina Inc. (US)
Siemens Healthineers AG (Germany)
Danaher Corporation (US)
Myriad Genetics Inc. (US)
Agilent Technologies Inc. (US)
Becton, Dickinson and Company (US)
DiaSorin S.p.A (Italy)
Grifols S.A. (Spain)
Quidel Corporation(US)
Genetic Signatures (Australia)
MDxHealth, Inc. (US)
Exact Sciences Corporation (US)
Biocartis NV (Belgium)
TBG Diagnostics Ltd. (Australia)
GenMark Diagnostics Inc. (US)
Luminex Corporation (US)
HTG Molecular Diagnostics Inc. (US)
Vela Diagnostics (Singapore)
Amoy Diagnostics Co., Ltd. (China)
Molbio Diagnostics Pvt. Ltd. (India)
ELITechGroup (France)
Savyon Diagnostics Ltd. (Israel)
ABACUS Diagnostica Oy (Finland)
geneOmbio Technologies Pvt. Ltd. (India)
Research Coverage:
This report provides a detailed picture of the global molecular diagnostics market. It aims at estimating the size and future growth potential of the market across different segments, such as product & service, technology, application, end user, and region. The report also includes an in-depth competitive analysis of the key market players, along with their company profiles, recent developments, and key market strategies.
Key Benefits of Buying the Report:
The report will help market leaders/new entrants by providing them with the closest approximations of the revenue numbers for the overall molecular diagnostics market and its sub segments. It will also help stakeholders better understand the competitive landscape and gain more insights to better position their business and make suitable go-to-market strategies. This report will enable stakeholders to understand the market’s pulse and provide them with information on the key market drivers, restraints, challenges, and opportunities.
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nuadox · 3 days ago
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Chronic kidney disease in cats: RenalTech encourages vet visits and better preventive care
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- By Antech Diagnostics -
California-based Antech Diagnostics, part of Mars Veterinary Health, released new data today showing that all cats from a retrospective review of 730,000 veterinary visits received improved preventive care following a positive or negative “RenalTech”, which predicts chronic kidney disease (CKD) in cats 2 years before it occurs. 
Data show the predictive diagnostic tool increased veterinary visits by as much as 31%. Additionally, pet owners proactively sought CKD-related early interventions, including food and medications. The findings support RenalTech's value as a diagnostic tool for veterinarians seeking to improve overall feline wellness while also positively impacting the health of cats facing CKD.
"With appropriate medical management, cats with chronic kidney disease can survive for a significant amount of time with good quality of life," said Jonathan Elliott, MA, Vet MB, PhD, Cert SAC, Dip ECVPT, MRCVS, Professor of Veterinary Clinical Pharmacology at Royal Veterinary College in London. "However, the perennial issue with cats has always been getting them in the door, and for cats with CKD, diagnosing them early enough for early care strategies to make a difference. With recent developments in diagnostic tests and ways of utilizing the data we gather from routine geriatric health screens, we now have a very real opportunity to impact both access to preventive care for all cats and improve on the duration of good quality of life of cats facing and living with CKD."
One in 3 cats will develop CKD in their lifetime. Diagnostics that go beyond early diagnosis to disease prediction allow veterinarians to begin monitoring and treating CKD when it is identified early, leading to interventions that are most effective at this stage. As veterinary medicine's first predictive diagnostic tool, RenalTech combines artificial intelligence and machine learning with 20 years of data from over 150,000 cats to predict whether or not a cat will develop CKD within 2 years with 95% accuracy. In the one-year, retrospective analysis of RenalTech's impact on preventive care practices, researchers found that regardless of a cat's positive or negative status, RenalTech use alone created opportunities for the following:
Early interventions to delay CKD onset and progression—pet owners with RenalTech-positive cats proactively sought proven early care strategies for CKD: 31.5% purchased renal therapeutic diets vs. only 4.8% percent of all other cats, and 41% purchased CKD-related medications vs. only 26.3% of all other cats.  
Improved preventive care for all cats—all cats regardless of RenalTech status received improved, sustained veterinary care. Visits from RenalTech-negative cats increased 14% year-over-year while visits from RenalTech-positive cats increased 31%.
"Cats don't like visiting the vet, and this simple fact has limited their access to preventive care for decades," said Dr. Jennifer Ogeer, DVM, MSc., MBA, MA, VP Medical Affairs & Commercial Marketing. "Now, we know that an early warning of disease is an incredibly powerful motivator for owners, who naturally respond to the opportunity to treat CKD proactively. Perhaps more importantly though, we also know from the data that regardless of status, RenalTech use alone improved all cats' access to preventive care. In this sense, and like RenalTech itself, the data is another first for veterinary medicine."
Responding to the opportunity to treat CKD before it occurs, Antech also offers veterinary medicine's only complete solution for disease prediction, early diagnosis, staging and monitoring. The diagnostic portfolio includes RenalTech as well as SDMA™ (symmetric dimethylarginine), the renal biomarker for CKD. Combined, these advanced diagnostics offer veterinarians a unique opportunity to support the best possible outlook for cats facing disease.
"RenalTech has been a great additional value to our patients and clients," said John Faught, DVM, Chief Medical Officer for Firehouse Animal Health Centers of Austin, TX. "At Firehouse Animal Health Center, we have long utilized routine lab work to assess our patients' evolving function. By evaluating those trends and spot checks, we have hoped to make a difference earlier in disease or aging processes. Never before, though, have we been able to use those values to actually predict the future of our pets' health. RenalTech intersects Antech's advanced laboratory testing with innovative statistical data analysis to provide truly preventive medicine instead of reactionary."
--
Source: Antech Diagnostics
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Researchers awarded $3 million to study neural dynamics of mental disorders
Researchers awarded $3 million to study neural dynamics of mental disorders
ATLANTA–Georgia State University researchers have received a five-year, $3 million grant from the National Institute of Mental Health to develop new strategies to identify mood disorders using whole brain dynamics, which considers changes in the shape, size or location of brain networks, as well as changes in the connections between brain networks. The researchers will use the approaches they…
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Amazon gives out $12M under next phase of AWS diagnostics development initiative
Amazon gives out $12M under next phase of AWS diagnostics development initiative
Amazon said on Monday that it is launching the next phase of its Amazon Web Services Diagnostic Development Initiative, in which it plans to distribute $12 million this year to fund projects for COVID testing, as well as for other infectious disease diagnostics. The company first launched the initiative in March 2020 as a way to accelerate research, innovation, and development of diagnostics for…
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Spit samples uncover genetic risk factors for paediatric obsessive-compulsive disorder
Researchers at the University of Calgary and The Hospital for Sick Children (SickKids), in Toronto, have discovered genetic risk factors for OCD that could help pave the way for earlier diagnosis and improved treatment for children and youth. “Our group made the first finding of a genome-wide significant risk gene relevant to childhood OCD,” says Dr. Paul Arnold, MD, PhD, co-principal…
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joyfuleggrascaltrash · 5 days ago
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Pb really out here letting me bond and joke about with Tobias then make him the new leader
And expect ME TO CARE
Like I like Tobias now so haha
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abdulmontaqim · 7 days ago
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SICK launches ‘world’s first’ LiDAR multibeam scanner for small vehicles
SICK launches ‘world’s first’ LiDAR multibeam scanner for small vehicles
SICK Sensor Intelligence has launched what it describes as “the world’s first” LiDAR multibeam scanner with safe, solid-state technology for line-guided small vehicles. The scanGrid2 safe multibeam scanner from SICK is the first of its kind in the world. The compact sensor uses a novel and in-house developed solid-state LiDAR technology to increase the productivity of small autonomous and…
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M2D2 $200K Challenge names pitch contest winners
M2D2 $200K Challenge names pitch contest winners
LOWELL, Mass. – A biotech startup that aims to transform how intravenous medications are administered to patients is the top winner in the 2021 Massachusetts Medical Device Development Center (M2D2) $200K Challenge. Now in its 10th year, the annual pitch contest drives innovations in health care by showcasing the pioneering work of early-stage medical device, diagnostic and biotech companies.…
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Chronic sinus inflammation appears to alter brain activity
Chronic sinus inflammation appears to alter brain activity
The millions of people who have chronic sinusitis deal not only with stuffy noses and headaches, they also commonly struggle to focus, and experience depression and other symptoms that implicate the brain’s involvement in their illness. New research links sinus inflammation with alterations in brain activity, specifically with the neural networks that modulate cognition, introspection and…
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New test to study language development in youth with Down syndrome
New test to study language development in youth with Down syndrome
Expressive language sampling (ELS) is a useful tool for measuring communication development in youth with Down syndrome, a new multi-site study has found. The study, co-led by Angela Thurman and Leonard Abbeduto from the UC Davis MIND Institute and the Department of Psychiatry and Behavioral Sciences, focused on language as an outcome measure to detect meaningful changes in communication skills…
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New study explains Mycobacterium tuberculosis high resistance to drugs and immunity
New study explains Mycobacterium tuberculosis high resistance to drugs and immunity
A consortium of researchers from Russia, Belarus, Japan, Germany and France led by a Skoltech scientist have uncovered the way in which Mycobacterium tuberculosis survives in iron-deficient conditions by utilizing rubredoxin B, a protein from a rubredoxin family that play an important role in adaptation to changing environmental conditions. The new study is part of an effort to study the role of…
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