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#Biochemistry
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Unlocking new avenues for curing cancer: Cell receptor neuropilin-1 could hold the key
Unlocking new avenues for curing cancer: Cell receptor neuropilin-1 could hold the key
Cancer is an insidious disease that, despite being around for centuries, is still very difficult to diagnose and treat. Thus, cancer has been the focus much research in the biomedical fields. Today, with research methods advancing rapidly and the base pool of researchers growing constantly, our fundamental understanding of the mechanisms of cancer formation and proliferation have increased, and…
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littlechemistsblog · 7 hours ago
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Watch "FUNCTION - MATHEMATICS FOR CLASSICAL THERMODYNAMICS.#backtobasics" on YouTube
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goodvibesandchemnotes · 15 hours ago
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Cool science post!!! Please enjoy! And keep in mind just because something has a higher LD50 (more needed to kill you, less toxic) doesnt mean it's magically Better. Aspirin has a lower LD50 than hydrochloric acid, vitamin D has a lower LD50 than cocaine, and nicotine has a lower LD50 than heroin. Also, this chart doesn't take into account chronic health effects or sub-lethal toxicity. Just how much is needed to kill you in one dose.
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A few things that stood out to me (assuming a statistically average, 70kg adult):
>MSG is 5 times less toxic than table salt, per gram (it has 5 times less sodium per gram). And it tastes better, too! The long term health effects (other than specific allergies, which are immediate) are minimal, its a misconception that it's extremely unhealthy.
>Botox will kill at 0.000000002 grams. And we inject it into our faces to look younger. What the heck, guys.
>LSD is dosed in increments of 100μg, or at about 50-100x BELOW its acute toxic dose. This is known as a "therapeutic window", how far is the useful dose from the toxic dose. LSD has a fantastic therapeutic window compared to many medicines, but its still so small (similar EFFECTIVE dose to fentanyl, 5000% higher LD50) that extreme caution must be taken in dosing. A toxic but nonlethal dose of LSD is gonna leave some bad psychological damage.
>you can eat twice as much Magic Eraser as you can table salt before dying. I have no idea what to do with this information, but there you go.
>you'll die if you drink 10% of your body weight in water. This is pretty hard to do, but there are vanishingly rare cases where people drink so much water that their blood cells explode.
>CBD technically has a lower LD50 than THC? Both are pretty non-toxic, it'd take 70 GRAMS of CBD at once to kill you, and it's usually dosed in MILLIgrams. However, a quarter of the LD50 of THC would be a very very bad time (ever had too many edibles?) while a quarter of the LD50 of CBD would likely just feel drunken.
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Do I know metabolism? No
Can I try to make it look pretty? Yes
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'Diverse and Pioneering' research | EurekAlert! Science News
‘Diverse and Pioneering’ research | EurekAlert! Science News
When UC Santa Barbara neurology professor Kenneth S. Kosik was a newly minted graduate in 1972, with bachelor’s and master’s degrees in English literature from Case Western University, becoming one of the foremost authorities in the field of Alzheimer’s research was probably nowhere on his radar. But that would soon change. “Even as an undergrad, I learned that what seemed impossibly remote…
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biotechtimes · 6 days ago
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IIT Gandhinagar Recruitment 2021 – Biotech / Biochem / Life Sciences Job
New Post has been published on https://biotechtimes.org/2021/04/09/iit-gandhinagar-recruitment-2021-biotech-biochem-life-sciences-job/
IIT Gandhinagar Recruitment 2021 – Biotech / Biochem / Life Sciences Job
IIT Gandhinagar Recruitment 2021
IIT Gandhinagar Recruitment 2021 – Biotech / Biochem / Life Sciences Job. Indian Institute of Technology Gandhinagar is recruiting for Junior Research Fellow (JRF) position. Interested candidates can check out the complete details below:
Biotech / Biochem / Life Sciences Job
Indian Institute of Technology Gandhinagar (IITGN) invites applications for Junior Research Fellow (JRF) for a research project funded by the Department of Biotechnology, GoI.
Remuneration: 31,000 INR per month + 16% HRA
Eligibility: MSc/MS/MTech in Biotechnology, Chemical Biology, Biochemistry, Cell Biology, Life Sciences, and Nanotechnology, etc. or allied subject areas from reputed institutes with either GATE or CSIR-UGC-NET or equivalent national level exam qualified.
Duration: Initial appointment is for 1 year, extendable up to one more year based on performance.
Job Description: The candidate will be required to set up the experiments for developing physical and chemical biology protocols for developing organic and biological nanoparticles, conjugating multiple biological ligands to programmed DNA nanodevices for interface with cells and tissues.
He/she will also have the opportunity to develop advanced laboratory skills (HPLC and Mass-spec, 3D cell culture models, biochemical and molecular biology procedures, live-cell microscopy, visits to experts on collaborations). The candidate should be a highly motivated, continuous learner who is able to work independently.
Application Procedure: Candidates must send their applications via e-mail to Prof. Dhiraj Bhatia (dhiraj.bhatia@iitgn.ac.in). The following documents must be sent as a single pdf attachment to the email:
Current CV with a list of publications
A one-page summary of previous research/work experience and why you are interested in joining for this project (Statement of Purpose).
The applications will continue to be screened until the position is filled. However, applications received before 25th April 2021 will be screened and given priority.
Queries may be directed to Prof. Dhiraj Bhatia
DHIRAJ DEVIDAS BHATIA, PhD Assistant Professor & DST Ramanujan Fellow Biological Engineering Discipline, Indian Institute of Technology Gandhinagar, Near Palaj, Gandhinagar 382355, Gujarat, India Phone no: +91-79-2395-2537 E-mail: dhiraj.bhatia@iitgn.ac.in and dhirajbhatia1@gmail.com Website: https://www.iitgn.ac.in/faculty/biology/dhiraj.htm
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bitchingbiomed · a day ago
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13.4.21 | days to first exam:2 6
A pretty slow day today. As you can see, I started reading through the section on neurohormone secretion in my copy of Yost's Cellular Physiology, and updated my grades in my academic tracker/bujo.
I also booked a place on an open day about funding for master's degrees & master's funding and prepared a few Quizlet sets for tomorrow. It doesn't feel like enough, but what is university if not academic impostor syndrome persevering, I guess.
🎧: Personal Jesus by Depeche Mode
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Are chemical pollutants altering the behaviour of wildlife and humans?
Are chemical pollutants altering the behaviour of wildlife and humans?
International scientists from around the world are warning that chemical pollutants in the environment have the potential to alter animal and human behaviour. A scientific forum of 30 experts formed a united agreement of concern about chemical pollutants and set up a roadmap to help protect the environment from behaviour altering chemicals. The conclusions of their work have been published today…
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New Skoltech sensor tracks 'stress hormone' in real time
New Skoltech sensor tracks ‘stress hormone’ in real time
Skoltech researchers have developed a prototype of a fluorescence-based sensor for continuous detection of cortisol concentrations in real time, which can help monitor various health conditions. The paper was published in the journal Talanta. Cortisol, a steroid hormone commonly known as the “stress hormone,” plays a significant role in the regulation of a range of physiological processes from…
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bitchingbiomed · 2 days ago
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13.4.21 | days to first exam: 27
I got a later start than I'd hoped today. In the true nature of Murphy's law, Everything Went Wrong All At Once.
Still, I managed a full cycle of Pomodoro sessions (eight sessions in total) and did summary sheets on immunology, autosomal dominant & recessive genetic disorders and gene manipulation. I've started doing some background reading into angiotensin and kidney disease too.
🎧: Slow Dancing In A Burning Room by John Mayer
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angeljaystudies · 2 days ago
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Found this super cute website and it makes me feel like I’m studying in my favorite little cáfe! I miss going out and studying so much!
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Researchers streamline molecular assembly line to design, test drug compounds
Researchers streamline molecular assembly line to design, test drug compounds
Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis. The work could allow scientists to improve existing antibiotics as well as design new drug candidates quickly and efficiently. Bacteria – such as E. coli – harness biosynthesis to create molecules that are difficult to make…
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New research shows how immune response to TB differs in babies
New research shows how immune response to TB differs in babies
The immune response to tuberculosis (TB) differs in adults and newborn babies due to the way immune cells use energy to kick into gear in a bid to kill the bacteria. This fresh discovery – just published in leading journal, Frontiers in Immunology – offers hope for improving treatments for what remains a deadly disease. TB is still one of the biggest infectious killers in the world and babies are…
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forbetterscience · 3 days ago
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The intellectual leaps of Joe Shapiro
The intellectual leaps of Joe Shapiro
The simple solution to the COVID-19 pandemic is charcoal. The little black pills you take when you have a bit of a tummy ache. Medicinal charcoal is a kind of fluffy wood coal, it seems to bind toxins in the gut when consumed, facilitating their removal. Red colobus monkeys eat charcoal to deal with their phenolic-heavy leaf diet (Struhsacker et al 1997). Another primate species, homo sapiens,…
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Scientists reveal COVID-19 news, next frontier in fighting substance abuse, more
Scientists reveal COVID-19 news, next frontier in fighting substance abuse, more
Contact: media@experimentalbiology.org Want to find out the latest insights into COVID-19, explore new medicines for fighting substance abuse or delve into cultural challenges facing the scientific community? The Experimental Biology (EB) 2021 meeting is your source for the latest research and discussion on today’s hot topics in science and medicine. EB 2021, to be held April 27-30, is the annual…
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goodvibesandchemnotes · 3 days ago
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Tbh the two types of vax are so cool for different reasons. J&J is a frankenvirus vaccine, Pfizer and Moderna are Ikea vaccines.
Pfizer/Moderna is the ikea dresser of vaccines; it gives your body instructions on how to make the vaccine internally. But its pure mRNA in a little bit of fat, so its extremely difficult to store and transport, and the instructions have to be given twice to make sure the body fully recognized them
J&J is like a traditional vaccine, except its a totally different type of virus; it's an adenovirus, not a coronavirus, but they put the covid19 spike protein on an adenovirus for the body to fight. Idk why adenovirus specifically, but since it's closer to a traditional vaccine, it's cheaper, easier to store and transport, and only requires one dose. However, it's significantly less effective at total prevention (still 100% severe), its basically a flu shot for covid19
So while here in the first world nobody wants J&J, it's a total game-changer for places that don't have the necessary freezer transport at -90°C
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