#90 days

[picasso22]

Today is day 90 of season 2

Thats reason enough for a rewatch, not that i needed a reason 😅

Here have some swee Charlie 😋

#heartstopper #joe locke #kit connor #charlie spring #nick nelson #90 days

[wooataes]

90 Days mini update

Just a quick tiny update to let the current taglist know that I am back and 90 Days will continue to run in the near future! If any of you guys would still like to be tagged in the story, feel free to let me know, or send me a message if you’d like to be taken off!

- Taelor 🥰💜✨

Taglist under the cut

90 Days Taglist:

If your username isn’t highlighted, you weren’t able to be tagged.

@discoveringthyself @cryptoidsblog @elenaramos1 @lidda @deolly @forevermoremagcon @iloverubberduckiez-blog @sana-b @m0chilattae @namjoonsslutakakoreanmanswhore @littlewolfieposts @hoseokslefteyebrow @sharethelovebeauty @satantrashpanda @softescapism @peachyjoonieot7 @itskpopwow @anonymous2505 @hxsxxk-180294 @original-internetmonster @jikooksgirl19 @kpopmakessmiles @smallbaby-cat @hd-junglebook @alektopatronum @malayanghiwaga @ms-starlight @kimsopejikook @rynjacobs @realisticstratosphere @supertweetycherry @humminbirdie @mooniieix @mounak @missmoxxiesworld @insomniatears @arminwluv @samararose21 @vbmnl @scentedsope @fubukiluvr @arimsplayground @zer0spac3 @decaffeinateddelusionschees-blog1 @jinnieyoonie @ericanoona @cheychey-4788 @hoebii @bi-chai-tea @azail80 @poppywrites41 @himawari-haebalagi @eclivpses @biggiecheesewantsyoursoul @misshale21 @blancflms @catgirl12348765 @bunbuniverse

#taelor talks #bts ot7 x reader #90 days #bts fluff #bts angst #bts x reader

[kennyisntavaliable]

90 days.

#90 days #palestine #Youtube

[elwastudies]

I am starting a 90 days productivity challenge, this right here is going to be my accountability journal, except it's on tumblr and free for anybody to join in.

#90 days #productivity #academia #pre med #biology #chemistry #physics #healthblr #self love #self care

[the-witch-of-saturn]

90 days sober!!! Lots of emotions today. I want to treat myself to something but budgeting lol so I got a slice of cheesecake, gonna go home and enjoy my treat and watch some of my favorite movies :) (wish I could have gotten a Lego set but ya know lol)

#sobriety #90 days #life update #hi #cheesecake #enjoying the little things

[abri-chan]

unashamed that i still watch trash shows like 90 days fiancee but the recent nicole and mahmoud storyline made me wanted to comment on something. specifically on that episode where she is pressured to wear a muslim swimsuit, and she is asking him if she needs to have underwear underneath.

the way he reacted, not only brushing her off, but all indignant and uncomfortable, like she said something dirty or disgusting or asked about something unfathomable made me realize how this culture change is reverting her to a confused little girl. and what i mean by that is simple: how a girl is confused and scared and has no women around her to help. how a little girl can get her period and cannot ask her father bc if not angry, he will look uncomfortable. how the education system doesn’t even talk about the female body and how even mothers don’t tell their daughters these things. it’s so dehumanizing, like something is wrong with you, and you are disgusting and how dare you talk about it, bc boys and men are about to throw a tantrum.

it’s the same behavior with this guy who she married, that he somewhat thinks women will figure out how to act, when acting is the oppressive way, as though covering their bodies or serving men is something natural women do. and how even when she is trying to be understanding and cover herself, he doesn’t want to help her and teach her about the culture, and there’s no female member in this culture that she is close to to help her. but even if there were, how the men in her life, her own husband, would at worst get mad at her for not knowing, and at best delegate that task to female members of his family.

is it worth it men continue to treat you like that? why do you let them get away with it.

#anime manga rambles #90 days #90 days fiancee

[anotherfagontheinternet]

#sobreity #cw alcohol #cw drugs #90 days

[gothylizzie]

90 days!

#halloween countdown #halloween #goth aesthetic #angel wish font #angel rhapsody font #90 days #countdown #my edit

[kryss000]

90 seconds

An emotion only last 90 seconds.

Seems inaccurate, right? If the emotion only last 90 seconds then why does the feeling hang around for days, weeks, or maybe even months?

Well first, we have to remember that our brain catalogs those negative emotions and experiences better than positive ones because it is doing its best to help keep us alive and safe.

With this in mind we can infer that our negative experiences are going to linger in our thoughts a lot longer than the good ones. So, simply put, every time you think about what made you feel bad your brain runs through the rolodex of emotions and pulls the exact one that was present at the initial negative experience, and now your brain is sending your whole body messages telling it that you are back in that negative scene.

Although you consciously know that you are not back in that situation, your subconscious does not, and by constantly thinking about the bad things that happened to us we constantly replicate the feelings along with the experience and those feelings begin to manifest into a whole mood, and now, you just feel mean, nasty, and negative.

The best thing we can do for ourselves is to try and put those memories behind us. Easier said than done, I know. But, now at least we know why those stupid feelings are hanging around.

#mental health #90 days #brainthings #emotions #itsokay #mental heath support #positive thoughts #negative thoughts #improve

[veronicaisnotonline]

Green Day solicit donations for HIV/AIDS organization, 1994

#Green Day #billie joe armstrong #tre cool #mike dirnt #rock #punk #music #90s #rock music #greenday

[poprocklyrics]

I feel the space that's in between us, convince myself that this is real love

90 Days, Pink ft. Wrabel

#pink #wrabel #90 days #hurts 2b human #music #lyrics #pop

[jayhaden]

90 Days Sober Today!

Today marks 90 days free from alcohol and cocaine use. To say I feel better, both physically and mentally, would be an understatement. The motivation I have and the amount I've accomplished in such a small amount of time is truly eye-opening. I can only imagine the number of opportunities I missed out on, because of my addiction. But, that's not the point. Today, I celebrate the progress I've made and the great things in store for me if I stick to it.

With that being said, it wasn't that long ago that I was still awake from the night before, hearing the birds chirping, knowing damn well I had to work in a few hours. I will not fall victim to the pink cloud syndrome. I will not fool myself into thinking that I'm a finished product. I know the work that is recovery is constant, and I'm committed to the work. I will keep stacking the bricks.

I know it's cliche...but seriously: If I can do this, anyone can. And to everyone on here that has reached out to me during this process: I love you! Heres to 90 more

#sobriety #alcohlism #recovery #alcohol #cocaine #90 days #sober

[shanemcretro]

GAHT Blood Test Results February 2024

A few milestones have been achieved this month. I’ve reached my third month of gender affirming hormone therapy (GAHT) and was able to get an estradiol implant (200mg, compounded). I kicked pregabalin as it wasn’t helping with my anxiety symptoms – but was helping with sleep… I also ceased indometacin successfully. Hemicrania continua is not being so continua now.

My phosphates, calcium and ALT levels. Ahhh yes. Let’s start with the ALT. My ALT was easy to fix, cease indometacin. I also took some milk thistle to help keep the old liver in tip top shape – with interesting consequences. I’ll circle back to this one later!

Phosphates and calcium, I do wonder if this is actually a bad thing to have lower numbers on these. A ionised calcium test was ordered and found to be in range, but so were my other calcium stats – this time. I’d only changed my calcium vitamin to a non-plant-based formula as I don’t get much calcium from milk. i.e. I don’t drink milk. End result – calcium levels are OK for now.

Now phosphates are in everything, it should be difficult to ingest this in low amounts. Thankfully, I have a good history owing to low blood iron and phosphate levels were ordered as a complementary test most of the time. Using this data we can see that I tend to be on the lower side of things. But since starting GAHT, record new lows. Some potential answers could be here and here.

My theory is either my spirulina (cyanobacteria) infused multivitamin is causing lowered calcium and phosphate levels leading to improved bone density. This could perhaps explain the historically lower phosphate levels as I’ve taken this particular multivitamin for a few years now. Then we have this (potato) gem from the second article.

Estrogen therapy (ET) is associated with lower serum calcium and phosphorus concentrations and is known to increase bone mineral density (BMD).

Estrogen and progesterone are very good at not causing osteoporosis. Menopause is a great example of what happens when hormones are absent and why hormone replacement therapy exists for older assigned female at birth (AFAB) people. This puts my mind at ease and we’ll be rechecking in three months.

Oh iron, sweet, sweet iron. I mean each blood test takes five vials of blood? I’ve given up on blood donations so we can rule that one out and it’s nothing cancer-related so… diet? To keep my ferritin (iron stores) up I’ll be taking 210 mg of elemental iron every other morning one hour before food. This maximises absorption as hepcidin, the enzyme that tells the iron to stay or go, is still sleepy.

Of course vitamin C can override this too if daily dosing was needed. As my levels haven’t reached critical yet, and I don’t enjoy the undesirable GI side effects of iron therapy, every other day gives me roughly half the issues! 😅

Onto hormones! Errrrr… why did prolactin double and zip outside the reference range in the space of two months. The GP wasn’t sure why and the endocrinologist said it’s not an issue unless it’s triple that number. I had a peek into some literature and pregnant women can have this level between 1000 and 8000 mIU/L. Remembering that pregnant women are not going to have those levels forever.

So what caused mine to spike? I believe it might have been the milk thistle I was taking to fix that pesky liver up from the indometacin damage. Information here, here and here. This has been ceased now so it should drop back within the reference range next blood test. Hold up, I was just reading this again.

In animals, milk thistle has been shown to stimulate bone mineralization. However, how it affects humans is currently unknown.

Hmmm, I wonder if my calcium and phosphate levels will also increase on next blood test without milk thistle supplementation. Something to look forward to as I was only on milk thistle for two weeks.

Ahh yes traditional sex hormones. One of the more interesting to look analyse. Keep in mind that all my blood tests are done in the trough – which should indicate the lowest concentrations.

On 6 mg oral estradiol valerate (2 mg thrice daily) and estradiol gel (Sandrena brand estradiol 0.1% gel 1g sachets twice daily) I scored a lovely 764 pmol/L. Previously with pill therapy (6 mg) it came in at 364 pmol/L. So a decent jump for just a bit of gel. Good result, so good in fact, I now I have two pellet implants (100mg each) in my left buttock for 200 mg of estradiol. It will be interesting to see how that stabilises over the next three months as they can fluctuate a bit early on.

On the progesterone (P4) front, folks tend to take it after being on estradiol for around 12 months. My endocrinologist doesn’t see any issue with starting it earlier. In AFAB puberty, estradiol peaks before progesterone even appears on the scene. Then again I am not exactly AFAB, so past performance may not be indicative of future performance.

For me, I see progesterone a counterweight against what is intended to be high-dose estrogen. With progesterone in the mix my skin is less dry which was one of my biggest gripes about estrogen monotherapy.

At least one of the metabolites produced, allopregnanolone, is a neurosteroid that acts on the GABAnergic system when taken orally – in a good way, I think. Interestingly enough in a similar way to alcohol, benzodiazepines and even to a lesser degree, pregabalin. Lesser degree in that pregabalin doesn’t touch the GABA receptors themselves, and instead mess with other systems that have a flow on effect to the GABAnergic system.

Oh I could ramble on for days about this sort of thing. Let’s look at the level itself. 9.1 nmol/L. Alright, that’s in the trough still so that’s quite good. Last dose would have been 12 hours ago. It puts me somewhere between pre-ovulation and mid-cycle. I have since doubled the dose on my endocrinologists recommendation.

There are other routes of administration (ROA) for progesterone, butt (ha!), my current compounded powder (200mg twice daily) is not compatible. I would need to purchase the non-compounded version to do that, and it’s not on my radar at this point in time as it is quite expensive.

Converting my 9.1 nmol/L to a US-friendly unit of 2.6 ng/mL helps locate where I am on these charts, you can see where I fit in. You’ll also maybe note that progesterone via the rectal ROA results in markedly different levels of progesterone, allopregnanolone and pregnanolone.

Which leads us onto finasteride which is a 5-alpha reductase inhibitor (5ARI). It stops this particular enzyme (5-alpha reductase) from doing what it wants to do. This is primarily used to stop testosterone (T) conversion to Dihydrotestosterone (DHT).

For assigned male at birth (AMAB) people, DHT gives you the gift of male pattern baldness provided you have the correct set of genes. As a transgender woman, I don’t really want to be bald if I can avoid it. So I started taking finasteride early on. However progesterone and finasteride both inhibit the 5-alpha reductase enzyme. And the finasteride, as it turns out affects a little more than just the 5AR enzyme.

Remember our little friend allopregnanolone from earlier? Blocked. What about isopregnanolone. Blocked. Finasteride is really quite a dirty drug with lots of off-target activity.

I’ve deemed it as unnecessary for the same reason I don’t take any testosterone blockers, such as cyproterone acetate or spironolactone. We’re going for estrogen dominance here. Women do have testosterone, but it isn’t the dominant sex hormone.

It is unclear if there is any added benefit to taking one of these medicines once your testosterone levels have been reduced into the female range through the use of other blockers.

The science behind it all is always a work in progress. But for now let’s keep that key phrase – estrogen dominance; the female hormone range, at the front of our minds.

If the presence of DHT makes male pattern baldness progress… what happens once I cease finasteride, will it also resume? Well, that’s where the next set of blood results come in.

Oh there it is, estrogen dominance achieved! Testosterone levels in AFAB have a reference range of less than 2.0 nmol/L (pre-menopause). And there I am sitting pretty at 1.1 nmol/L. My sex hormone binding globulin (SHBG) is heading up and up. I can’t find the document I had, I am sure it said above 115 nmol/L can result in estrogens being bound. In lieu of that article, from Wikipedia.

The relative binding affinity of various sex steroids for SHBG is dihydrotestosterone (DHT) > testosterone > androstenediol > estradiol > estrone. DHT binds to SHBG with about 5 times the affinity of testosterone and about 20 times the affinity of estradiol.

So having a high SHBG level is a good thing, the higher the better. Bind all the sex hormones so they can’t be used – male ones are lost first, then the female ones. That means goodbye any DHT generated by the mere 1.1 nmol/L of T.

The calculated free testosterone being below 25 pmol/L is also a great sign things are heading in the right direction. This is why testosterone blocking isn’t required for me. I really do enjoy delving into this sort of data and getting a better understanding of what it all means. So that’s it for now. I look forward to my next set of results sometime in May. 🙃

https://mcretro.net/blood-test-results-february-2024/

#estrogen monotherapy #estradiol #GAHT #trans hrt #mtf #transgender #transfem #blood work #blood results #SHBG #pregabalin #milk thistle #DHT #90 days #finasteride #progesterone #spironolactone #cyproterone acetate #i spent too much time writing this up

[itaintfair]

#project pat #90 days #Youtube